Leslie A. Lange, Ph.D. - Publications

Affiliations: 
2000 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Public Health, Epidemiology

230 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hasbani NR, Westerman KE, Heon Kwak S, Chen H, Li X, Dicorpo D, Wessel J, Bis JC, Sarnowski C, Wu P, Bielak LF, Guo X, Heard-Costa N, Kinney G, Mahaney MC, ... ... Lange LA, et al. Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis. Circulation. Genomic and Precision Medicine. e004176. PMID 38014529 DOI: 10.1161/CIRCGEN.123.004176  0.526
2023 Kavousi M, Bos MM, Barnes HJ, Cardenas CLL, Wong D, Lu H, Hodonsky CJ, Landsmeer LPL, Turner AW, Kho M, Hasbani NR, de Vries PS, Bowden DW, Chopade S, Deelen J, ... ... Lange LA, et al. Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification. Nature Genetics. PMID 37770635 DOI: 10.1038/s41588-023-01518-4  0.578
2023 Zhang X, Brody JA, Graff M, Highland HM, Chami N, Xu H, Wang Z, Ferrier K, Chittoor G, Josyula NS, Li X, Li Z, Allison MA, Becker DM, Bielak LF, ... ... Lange LA, et al. WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE. Medrxiv : the Preprint Server For Health Sciences. PMID 37662265 DOI: 10.1101/2023.08.21.23293271  0.378
2023 van de Vegte YJ, Eppinga RN, van der Ende MY, Hagemeijer YP, Mahendran Y, Salfati E, Smith AV, Tan VY, Arking DE, Ntalla I, Appel EV, Schurmann C, Brody JA, Rueedi R, Polasek O, ... ... Lange L, et al. Genetic insights into resting heart rate and its role in cardiovascular disease. Nature Communications. 14: 4646. PMID 37532724 DOI: 10.1038/s41467-023-39521-2  0.565
2023 Huffman JE, Nicolas J, Hahn J, Heath AS, Raffield LM, Yanek LR, Brody JA, Thibord F, Almasy L, Bartz TM, Bielak LF, Bowler RP, Carrasquilla GD, Chasman DI, Chen MH, ... ... Lange LA, et al. Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles. Medrxiv : the Preprint Server For Health Sciences. PMID 37398003 DOI: 10.1101/2023.06.07.23291095  0.391
2023 Suzuki K, Hatzikotoulas K, Southam L, Taylor HJ, Yin X, Lorenz KM, Mandla R, Huerta-Chagoya A, Rayner NW, Bocher O, Ana Luiza de SVA, Sonehara K, Namba S, Lee SSK, Preuss MH, ... ... Lange LA, et al. Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications. Medrxiv : the Preprint Server For Health Sciences. PMID 37034649 DOI: 10.1101/2023.03.31.23287839  0.582
2023 Westerman KE, Walker ME, Gaynor SM, Wesse J, DiCorpo D, Ma J, Alonso A, Aslibekyan S, Baldridge AS, Bertoni AG, Biggs ML, Brody JA, Chen YI, Dupuis J, Goodarzi MO, ... ... Lange L, et al. Investigating gene-diet interactions impacting the association between macronutrient intake and glycemic traits. Diabetes. PMID 36791419 DOI: 10.2337/db22-0851  0.357
2022 Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, ... ... Lange LA, et al. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis. Genome Biology. 23: 268. PMID 36575460 DOI: 10.1186/s13059-022-02837-1  0.558
2022 Li X, Quick C, Zhou H, Gaynor SM, Liu Y, Chen H, Selvaraj MS, Sun R, Dey R, Arnett DK, Bielak LF, Bis JC, Blangero J, Boerwinkle E, Bowden DW, ... ... Lange LA, et al. Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies. Nature Genetics. PMID 36564505 DOI: 10.1038/s41588-022-01225-6  0.577
2022 Pan Y, Sun X, Mi X, Huang Z, Hsu Y, Hixson JE, Munzy D, Metcalf G, Franceschini N, Tin A, Köttgen A, Francis M, Brody JA, Kestenbaum B, Sitlani CM, ... ... Lange LA, et al. Whole-Exome Sequencing Study Identifies Four Novel Gene Loci Associated with Diabetic Kidney Disease. Human Molecular Genetics. PMID 36444934 DOI: 10.1093/hmg/ddac290  0.609
2022 Durda P, Raffield LM, Lange EM, Olson NC, Jenny NS, Cushman M, Deichgraeber P, Grarup N, Jonsson A, Hansen T, Mychaleckyj JC, Psaty BM, Reiner AP, Tracy RP, Lange LA. Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study. Journal of the American Heart Association. e024374. PMID 36314488 DOI: 10.1161/JAHA.121.024374  0.331
2022 Li Z, Li X, Zhou H, Gaynor SM, Selvaraj MS, Arapoglou T, Quick C, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Auer PL, Bielak LF, Bis JC, ... ... Lange LA, et al. A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies. Nature Methods. PMID 36303018 DOI: 10.1038/s41592-022-01640-x  0.599
2022 Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, ... ... Lange LA, et al. A saturated map of common genetic variants associated with human height. Nature. PMID 36224396 DOI: 10.1038/s41586-022-05275-y  0.631
2022 Selvaraj MS, Li X, Li Z, Pampana A, Zhang DY, Park J, Aslibekyan S, Bis JC, Brody JA, Cade BE, Chuang LM, Chung RH, Curran JE, de Las Fuentes L, de Vries PS, ... ... Lange L, et al. Whole genome sequence analysis of blood lipid levels in >66,000 individuals. Nature Communications. 13: 5995. PMID 36220816 DOI: 10.1038/s41467-022-33510-7  0.588
2022 Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, ... ... Lange LA, et al. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. American Journal of Human Genetics. 109: 1366-1387. PMID 35931049 DOI: 10.1016/j.ajhg.2022.06.012  0.583
2022 Tcheandjieu C, Zhu X, Hilliard AT, Clarke SL, Napolioni V, Ma S, Lee KM, Fang H, Chen F, Lu Y, Tsao NL, Raghavan S, Koyama S, Gorman BR, Vujkovic M, ... ... Lange LA, et al. Large-scale genome-wide association study of coronary artery disease in genetically diverse populations. Nature Medicine. PMID 35915156 DOI: 10.1038/s41591-022-01891-3  0.365
2022 DiCorpo D, Gaynor SM, Russell EM, Westerman KE, Raffield LM, Majarian TD, Wu P, Sarnowski C, Highland HM, Jackson A, Hasbani NR, de Vries PS, Brody JA, Hidalgo B, Guo X, ... ... Lange L, et al. Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program. Communications Biology. 5: 756. PMID 35902682 DOI: 10.1038/s42003-022-03702-4  0.591
2022 Raghavan S, Huang J, Tcheandjieu C, Huffman JE, Litkowski E, Liu C, Ho YA, Hunter-Zinck H, Zhao H, Marouli E, North KE, Lange E, Lange LA, Voight BF, Gaziano JM, et al. A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program. Plos Genetics. 18: e1010193. PMID 35653334 DOI: 10.1371/journal.pgen.1010193  0.304
2022 Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, ... ... Lange LA, et al. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nature Genetics. PMID 35551307 DOI: 10.1038/s41588-022-01058-3  0.602
2022 Wainschtein P, Jain D, Zheng Z, Cupples LA, Shadyab AH, McKnight B, Shoemaker BM, Mitchell BD, Psaty BM, Kooperberg C, Liu CT, Albert CM, Roden D, Chasman DI, Darbar D, ... ... Lange LA, et al. Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data. Nature Genetics. PMID 35256806 DOI: 10.1038/s41588-021-00997-7  0.352
2021 Hindy G, Dornbos P, Chaffin MD, Liu DJ, Wang M, Selvaraj MS, Zhang D, Park J, Aguilar-Salinas CA, Antonacci-Fulton L, Ardissino D, Arnett DK, Aslibekyan S, Atzmon G, Ballantyne CM, ... ... Lange LA, et al. Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. American Journal of Human Genetics. PMID 34932938 DOI: 10.1016/j.ajhg.2021.11.021  0.594
2021 Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, ... ... Lange LA, et al. The power of genetic diversity in genome-wide association studies of lipids. Nature. PMID 34887591 DOI: 10.1038/s41586-021-04064-3  0.362
2021 Mikhaylova AV, McHugh CP, Polfus LM, Raffield LM, Boorgula MP, Blackwell TW, Brody JA, Broome J, Chami N, Chen MH, Conomos MP, Cox C, Curran JE, Daya M, Ekunwe L, ... ... Lange LA, et al. Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program. American Journal of Human Genetics. PMID 34582791 DOI: 10.1016/j.ajhg.2021.08.007  0.372
2021 Lu Y, Dimitrov L, Chen SH, Bielak LF, Bis JC, Feitosa MF, Lu L, Kavousi M, Raffield LM, Smith AV, Wang L, Weiss S, Yao J, Zhu J, Gudmundsson EF, ... ... Lange LA, et al. Multiethnic Genome-wide Association Study of Subclinical Atherosclerosis in Individuals with Type 2 Diabetes. Circulation. Genomic and Precision Medicine. PMID 34241534 DOI: 10.1161/CIRCGEN.120.003258  0.613
2021 Lu Y, Dimitrov L, Chen SH, Bielak LF, Bis JC, Feitosa MF, Lu L, Kavousi M, Raffield LM, Smith AV, Wang L, Weiss S, Yao J, Zhu J, Gudmundsson EF, ... ... Lange LA, et al. Multiethnic Genome-wide Association Study of Subclinical Atherosclerosis in Individuals with Type 2 Diabetes. Circulation. Genomic and Precision Medicine. PMID 34241534 DOI: 10.1161/CIRCGEN.120.003258  0.613
2021 Goodrich JK, Singer-Berk M, Son R, Sveden A, Wood J, England E, Cole JB, Weisburd B, Watts N, Caulkins L, Dornbos P, Koesterer R, Zappala Z, Zhang H, Maloney KA, ... ... Lange L, et al. Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes. Nature Communications. 12: 3505. PMID 34108472 DOI: 10.1038/s41467-021-23556-4  0.306
2021 Chen J, Spracklen CN, Marenne G, Varshney A, Corbin LJ, Luan J, Willems SM, Wu Y, Zhang X, Horikoshi M, Boutin TS, Mägi R, Waage J, Li-Gao R, Chan KHK, ... ... Lange LA, et al. The trans-ancestral genomic architecture of glycemic traits. Nature Genetics. PMID 34059833 DOI: 10.1038/s41588-021-00852-9  0.583
2021 Sarnowski C, Cousminer DL, Franceschini N, Raffield LM, Jia G, Fernández-Rhodes L, Grant SFA, Hakonarson H, Lange LA, Long J, Sofer T, Tao R, Wallace RB, Wong Q, Zirpoli G, et al. Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche. Human Reproduction (Oxford, England). PMID 34021356 DOI: 10.1093/humrep/deab086  0.321
2021 Stanislawski MA, Lange LA, Raffield LM, Zakai NA, Meyer M, Ferrier K, Szeto M, Leavitt C, Shortt JA, Thornton TA, Tracy RP, Auer PL, Reiner AP, Lange EM, Olson NC. Soluble CD14 Levels in the Jackson Heart Study: Associations With Cardiovascular Disease Risk and Genetic Variants. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA121316035. PMID 33910371 DOI: 10.1161/ATVBAHA.121.316035  0.324
2021 Hu Y, Stilp AM, McHugh CP, Rao S, Jai D, Zheng X, Lane J, Méric de Bellefon S, Raffield LM, Chen MH, Yanek LR, Wheeler M, Yao Y, Ren C, Broome J, ... ... Lange LA, et al. Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. American Journal of Human Genetics. PMID 33887194 DOI: 10.1016/j.ajhg.2021.04.003  0.382
2021 Natarajan P, Pampana A, Graham SE, Ruotsalainen SE, Perry JA, de Vries PS, Broome JG, Pirruccello JP, Honigberg MC, Aragam K, Wolford B, Brody JA, Antonacci-Fulton L, Arden M, Aslibekyan S, ... ... Lange L, et al. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. Nature Communications. 12: 2182. PMID 33846329 DOI: 10.1038/s41467-021-22339-1  0.575
2021 Graff M, Justice AE, Young KL, Marouli E, Zhang X, Fine RS, Lim E, Buchanan V, Rand K, Feitosa MF, Wojczynski MK, Yanek LR, Shao Y, Rohde R, Adeyemo AA, ... ... Lange L, et al. Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. American Journal of Human Genetics. PMID 33713608 DOI: 10.1016/j.ajhg.2021.02.011  0.617
2021 Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Niroula A, ... ... Lange L, et al. Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. PMID 33707633 DOI: 10.1038/s41586-021-03280-1  0.517
2021 Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, ... ... Lange LA, et al. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 590: 290-299. PMID 33568819 DOI: 10.1038/s41586-021-03205-y  0.593
2020 Gorski M, Jung B, Li Y, Matias-Garcia PR, Wuttke M, Coassin S, Thio CHL, Kleber ME, Winkler TW, Wanner V, Chai JF, Chu AY, Cocca M, Feitosa MF, Ghasemi S, ... ... Lange LA, et al. Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. Kidney International. PMID 33137338 DOI: 10.1016/j.kint.2020.09.030  0.347
2020 Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM, Szeto MD, Liao X, Leventhal MJ, Nasser J, Chang K, Laurie C, Burugula BB, Gibson CJ, Lin AE, ... ... Lange L, et al. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. PMID 33057201 DOI: 10.1038/s41586-020-2819-2  0.601
2020 Yaghootkar H, Zhang Y, Spracklen CN, Karaderi T, Huang LO, Bradfield J, Schurmann C, Fine RS, Preuss MH, Kutalik Z, Wittemans LB, Lu Y, Metz S, Willems SM, Li-Gao R, ... ... Lange LA, et al. Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity. Diabetes. PMID 32917775 DOI: 10.2337/Db20-0070  0.419
2020 Vuckovic D, Bao EL, Akbari P, Lareau CA, Mousas A, Jiang T, Chen MH, Raffield LM, Tardaguila M, Huffman JE, Ritchie SC, Megy K, Ponstingl H, Penkett CJ, Albers PK, ... ... Lange LA, et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell. 182: 1214-1231.e11. PMID 32888494 DOI: 10.1016/J.Cell.2020.08.008  0.392
2020 Chen MH, Raffield LM, Mousas A, Sakaue S, Huffman JE, Moscati A, Trivedi B, Jiang T, Akbari P, Vuckovic D, Bao EL, Zhong X, Manansala R, Laplante V, Chen M, ... ... Lange LA, et al. Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations. Cell. 182: 1198-1213.e14. PMID 32888493 DOI: 10.1016/J.Cell.2020.06.045  0.426
2020 Keene KL, Hyacinth HI, Bis JC, Kittner SJ, Mitchell BD, Cheng YC, Pare G, Chong M, O'Donnell M, Meschia JF, Chen WM, Sale MM, Rich SS, Nalls MA, Zonderman AB, ... ... Lange LA, et al. Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke. Stroke. STROKEAHA120029123. PMID 32693751 DOI: 10.1161/Strokeaha.120.029123  0.311
2020 Leavitt C, Zakai NA, Auer P, Cushman M, Lange EM, Levitan EB, Olson N, Thornton TA, Tracy RP, Wilson JG, Lange LA, Reiner AP, Raffield LM. Interferon gamma-induced protein 10 (IP-10) and cardiovascular disease in African Americans. Plos One. 15: e0231013. PMID 32240245 DOI: 10.1371/Journal.Pone.0231013  0.343
2020 Stanislawski MA, Shaw J, Litkowski E, Lange EM, Perng W, Dabelea D, Lange LA. Genetic Risk for Hepatic Fat among an Ethnically Diverse Cohort of Youth: The Exploring Perinatal Outcomes among Children Study. The Journal of Pediatrics. PMID 32143931 DOI: 10.1016/J.Jpeds.2020.01.031  0.327
2020 Van Tassell JC, Shimbo D, Hess R, Kittles R, Wilson JG, Jorde LB, Li M, Lange LA, Lange EM, Muntner P, Bress AP. Association of West African ancestry and blood pressure control among African Americans taking antihypertensive medication in the Jackson Heart Study. Journal of Clinical Hypertension (Greenwich, Conn.). PMID 32049421 DOI: 10.1111/Jch.13824  0.301
2020 Raffield LM, Lu AT, Szeto MD, Little A, Grinde KE, Shaw J, Auer PL, Cushman M, Horvath S, Irvin MR, Lange EM, Lange LA, Nickerson DA, Thornton TA, Wilson JG, et al. Coagulation factor VIII: Relationship to Cardiovascular Disease Risk and Whole Genome Sequence and Epigenome-Wide Analysis in African Americans. Journal of Thrombosis and Haemostasis : Jth. PMID 31985870 DOI: 10.1111/Jth.14741  0.378
2020 Vince N, Limou S, Daya M, Morii W, Rafaels N, Geffard E, Douillard V, Walencik A, Boorgula MP, Chavan S, Vergara C, Ortega VE, Wilson JG, Lange LA, Watson H, et al. Association of HLA-DRB1*09:01 with tIgE levels among African ancestry individuals with asthma. The Journal of Allergy and Clinical Immunology. PMID 31981624 DOI: 10.1016/J.Jaci.2020.01.011  0.336
2020 Tobias DK, Raghavan S, Bick A, Raffield L, Wu P, Dicorpo DA, Dupuis J, Lange L, Rotter JI, Kooperberg CL, Meigs JB, Manson JE. 2256-PUB: Clonal Hematopoiesis of Indeterminate Potential (CHIP), Glycemic Traits, and Type 2 Diabetes (T2D) Risk Diabetes. 69. DOI: 10.2337/Db20-2256-Pub  0.402
2020 Onengut-Gumuscu S, Paila UD, Chen W, Ratan A, Zhu Z, Steck A, Frohnert BI, Waugh K, Webb-Robertson B, Norris JM, Lange L, Rewers M, Rich SS. 107-OR: Novel Genetic Risk Factors Influence Islet Autoimmunity Progression Diabetes. 69. DOI: 10.2337/Db20-107-Or  0.458
2020 Szeto MD, Raffield LM, Nickerson DA, Zakai NA, Klemm DJ, Taylor MR, Yang IV, Correa A, Reiner AP, Lange EM, Lange LA. Abstract 25: Epigenome-Wide DNA Methylation Analysis Reveals Novel Hematologic Trait Associations for African Americans in The Jackson Heart Study Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.25  0.345
2019 Raffield LM, Iyengar AK, Wang B, Gaynor SM, Spracklen CN, Zhong X, Kowalski MH, Salimi S, Polfus LM, Benjamin EJ, Bis JC, Bowler R, Cade BE, Choi WJ, Comellas AP, ... ... Lange LA, et al. Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts. American Journal of Human Genetics. PMID 31883642 DOI: 10.1016/J.Ajhg.2019.12.002  0.477
2019 de Las Fuentes L, Sung YJ, Sitlani CM, Avery CL, Bartz TM, Keyser C, Evans DS, Li X, Musani SK, Ruiter R, Smith AV, Sun F, Trompet S, Xu H, Arnett DK, ... ... Lange L, et al. Genome-wide meta-analysis of variant-by-diuretic interactions as modulators of lipid traits in persons of European and African ancestry. The Pharmacogenomics Journal. PMID 31806883 DOI: 10.1038/S41397-019-0132-Y  0.455
2019 Chaudhary NS, Moore JX, Zakai NA, Judd SE, Naik RP, Limou S, Cushman M, Lange LA, Wang HE, Winkler CA, Irvin MR, Kopp JB, Gutiérrez OM. Nephropathy Risk Alleles and Risk of Sepsis in Blacks. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 31704668 DOI: 10.2215/Cjn.04490419  0.337
2019 Schmidt AF, Holmes MV, Preiss D, Swerdlow DI, Denaxas S, Fatemifar G, Faraway R, Finan C, Valentine D, Fairhurst-Hunter Z, Hartwig FP, Horta BL, Hypponen E, Power C, Moldovan M, ... ... Lange LA, et al. Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9. Bmc Cardiovascular Disorders. 19: 240. PMID 31664920 DOI: 10.1186/S12872-019-1187-Z  0.402
2019 Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, Sieber KB, Qiu C, Gorski M, Yu Z, Giri A, Sveinbjornsson G, Li M, Chu AY, Hoppmann A, ... ... Lange LA, et al. Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nature Genetics. PMID 31578528 DOI: 10.1038/S41588-019-0504-X  0.411
2019 Irvin MR, Sitlani CM, Floyd JS, Psaty BM, Bis JC, Wiggins KL, Whitsel EA, Sturmer T, Stewart J, Raffield L, Sun F, Liu CT, Xu H, Cupples AL, Tanner RM, ... ... Lange L, et al. Genome wide association study of apparent treatment resistant hypertension in the CHARGE consortium: The CHARGE Pharmacogenetics Working Group. American Journal of Hypertension. PMID 31545351 DOI: 10.1093/Ajh/Hpz150  0.304
2019 Teumer A, Li Y, Ghasemi S, Prins BP, Wuttke M, Hermle T, Giri A, Sieber KB, Qiu C, Kirsten H, Tin A, Chu AY, Bansal N, Feitosa MF, Wang L, ... ... Lange LA, et al. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nature Communications. 10: 4130. PMID 31511532 DOI: 10.1038/S41467-019-11576-0  0.452
2019 Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N, Auer PL, Bartz TM, Blüher M, ... ... Lange LA, et al. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. American Journal of Human Genetics. 105: 670-671. PMID 31491410 DOI: 10.1016/J.Ajhg.2019.08.001  0.349
2019 Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, ... ... Lange LA, et al. Author Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nature Communications. 10: 4082. PMID 31484942 DOI: 10.1038/S41467-019-12158-W  0.314
2019 Do AN, Zhao W, Baldridge AS, Raffield LM, Wiggins KL, Shah SJ, Aslibekyan S, Tiwari HK, Limdi N, Zhi D, Sitlani CM, Taylor KD, Psaty BM, Sotoodehnia N, Brody JA, ... ... Lange LA, et al. Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans. Molecular Genetics & Genomic Medicine. e788. PMID 31407531 DOI: 10.1002/Mgg3.788  0.385
2019 Sofer T, Emery L, Jain D, Ellis AM, Laurie CC, Allison MA, Lee J, Kurniansyah N, Kerr KF, González HM, Tarraf W, Criqui MH, Lange LA, Palmas WR, Franceschini N, et al. Variants Associated with the Ankle Brachial Index Differ by Hispanic/Latino Ethnic Group: a genome-wide association study in the Hispanic Community Health Study/Study of Latinos. Scientific Reports. 9: 11410. PMID 31388106 DOI: 10.1038/S41598-019-47928-5  0.467
2019 Spracklen CN, Karaderi T, Yaghootkar H, Schurmann C, Fine RS, Kutalik Z, Preuss MH, Lu Y, Wittemans LBL, Adair LS, Allison M, Amin N, Auer PL, Bartz TM, Blüher M, ... ... Lange LA, et al. Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology. American Journal of Human Genetics. PMID 31178129 DOI: 10.1016/J.Ajhg.2019.05.002  0.47
2019 Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, ... ... Lange LA, et al. Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Nature Genetics. PMID 31160810 DOI: 10.1038/S41588-019-0449-0  0.323
2019 Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, ... ... Lange LA, et al. Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics. PMID 31160809 DOI: 10.1038/s41588-019-0447-2  0.507
2019 Flannick J, Mercader JM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, Teslovich TM, Caulkins L, Koesterer R, Barajas-Olmos F, Blackwell TW, Boerwinkle E, Brody JA, Centeno-Cruz F, Chen L, ... ... Lange L, et al. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. PMID 31118516 DOI: 10.1038/s41586-019-1231-2  0.33
2019 Douce DR, Soliman EZ, Naik R, Hyacinth HI, Cushman M, Winkler CA, Howard G, Lange EM, Lange LA, Irvin MR, Zakai NA. Association of sickle cell trait with atrial fibrillation: The REGARDS cohort. Journal of Electrocardiology. 55: 1-5. PMID 31028976 DOI: 10.1016/J.Jelectrocard.2019.04.010  0.317
2019 Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, ... ... Lange LA, et al. Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nature Communications. 10: 880. PMID 30787307 DOI: 10.1038/S41467-019-08469-7  0.348
2019 Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL, Fine RS, Guo X, Schurmann C, Lempradl A, Marouli E, Mahajan A, Winkler TW, ... ... Lange LA, et al. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics. PMID 30778226 DOI: 10.1038/S41588-018-0334-2  0.399
2019 Zhao X, Geng X, Srinivasasainagendra V, Chaudhary N, Judd S, Wadley V, Gutiérrez OM, Wang H, Lange EM, Lange LA, Woo D, Unverzagt FW, Safford M, Cushman M, Limdi N, et al. A PheWAS study of a large observational epidemiological cohort of African Americans from the REGARDS study. Bmc Medical Genomics. 12: 26. PMID 30704471 DOI: 10.1186/S12920-018-0462-7  0.32
2019 Sofer T, Zheng X, Gogarten SM, Laurie CA, Grinde K, Shaffer JR, Shungin D, O'Connell JR, Durazo-Arvizo RA, Raffield L, Lange L, Musani S, Vasan RS, Cupples LA, Reiner AP, et al. A fully adjusted two-stage procedure for rank-normalization in genetic association studies. Genetic Epidemiology. PMID 30653739 DOI: 10.1002/Gepi.22188  0.398
2019 CHEN L, SRINIVASAN S, SANTORO N, TODD J, DIVERS J, SHAH AS, GIDDING S, BURKE BK, HAYMOND MW, LANGE L, MARCOVINA SM, CHAIT A, FLANNICK J, CAPRIO S, FLOREZ JC. 177-OR: Genome-Wide Association Study of Lipid Traits in Youth with Type 2 Diabetes: The ProDiGY (Progress in Diabetes Genetics in Youth) Consortium Diabetes. 68: 177-OR. DOI: 10.2337/Db19-177-Or  0.451
2019 Ruhl AP, Jeffries N, Yang Y, Naik RP, Pecker LH, Mott BT, Zakai NA, Winkler CA, Kopp JB, Lange LA, Irvin MR, Gutierrez OM, Cushman M, Ackerman HC. Alpha Globin Gene Copy Number Is Associated with Kidney Disease Among Black Individuals Blood. 134: 2248-2248. DOI: 10.1182/Blood-2019-121493  0.349
2018 Sherman RM, Forman J, Antonescu V, Puiu D, Daya M, Rafaels N, Boorgula MP, Chavan S, Vergara C, Ortega VE, Levin AM, Eng C, Yazdanbakhsh M, Wilson JG, Marrugo J, ... Lange LA, et al. Assembly of a pan-genome from deep sequencing of 910 humans of African descent. Nature Genetics. PMID 30455414 DOI: 10.1038/S41588-018-0273-Y  0.337
2018 Polfus LM, Raffield LM, Wheeler MM, Tracy RP, Lange LA, Lettre G, Miller A, Correa A, Bowler RP, Bis JC, Salimi S, Jenny NS, Pankratz N, Wang B, Preuss MH, et al. Whole genome sequence association with E-selectin levels reveals Loss-of-function variant in African Americans. Human Molecular Genetics. PMID 30307499 DOI: 10.1093/Hmg/Ddy360  0.45
2018 Chatterjee R, Davenport CA, Raffield LM, Maruthur N, Lange L, Selvin E, Butler K, Yeh HC, Wilson JG, Correa A, Edelman D, Hauser E. KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts. Plos One. 13: e0203213. PMID 30169531 DOI: 10.1371/Journal.Pone.0203213  0.323
2018 Wyss AB, Sofer T, Lee MK, Terzikhan N, Nguyen JN, Lahousse L, Latourelle JC, Smith AV, Bartz TM, Feitosa MF, Gao W, Ahluwalia TS, Tang W, Oldmeadow C, Duan Q, ... ... Lange L, et al. Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Nature Communications. 9: 2976. PMID 30061609 DOI: 10.1038/S41467-018-05369-0  0.431
2018 Oelsner EC, Balte PP, Cassano P, Couper D, Enright PL, Folsom AR, Hankinson J, Jacobs DR, Kalhan R, Kaplan R, Kronmal R, Lange L, Loehr LR, London SJ, Acien AN, et al. Harmonization of Respiratory Data From Nine US Population-Based Cohorts: The NHLBI Pooled Cohorts Study. American Journal of Epidemiology. PMID 29982273 DOI: 10.1093/Aje/Kwy139  0.309
2018 Irvin MR, Sitlani CM, Noordam R, Avery CL, Bis JC, Floyd JS, Li J, Limdi NA, Srinivasasainagendra V, Stewart J, de Mutsert R, Mook-Kanamori DO, Lipovich L, Kleinbrink EL, Smith A, ... ... Lange LA, et al. Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry. The Pharmacogenomics Journal. PMID 29855607 DOI: 10.1038/S41397-018-0021-9  0.416
2018 Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H, Taliun D, Rayner NW, Guo X, Lu Y, Li M, Jensen RA, Hu Y, ... ... Lange LA, et al. Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nature Genetics. 50: 559-571. PMID 29632382 DOI: 10.1038/S41588-018-0084-1  0.621
2018 Spracklen CN, Shi J, Vadlamudi S, Wu Y, Zou M, Raulerson CK, Davis JP, Zeynalzadeh M, Jackson K, Yuan W, Wang H, Shou W, Wang Y, Luo J, Lange LA, et al. Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey. Plos Genetics. 14: e1007275. PMID 29621232 DOI: 10.1371/Journal.Pgen.1007275  0.433
2018 Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, ... ... Lange LA, et al. Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics. PMID 29549330 DOI: 10.1038/s41588-018-0082-3  0.485
2018 Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, ... ... Lange LA, et al. Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics. PMID 29549329 DOI: 10.1038/S41588-018-0050-Y  0.55
2018 Booth JN, Li M, Shimbo D, Hess R, Irvin MR, Kittles R, Wilson JG, Jorde LB, Cheung AK, Lange LA, Lange EM, Yano Y, Muntner P, Bress AP. West African ancestry and nocturnal blood pressure in African Americans: the Jackson Heart Study. American Journal of Hypertension. PMID 29528363 DOI: 10.1093/Ajh/Hpy038  0.301
2018 Raffield LM, Ellis J, Olson NC, Duan Q, Li J, Durda P, Pankratz N, Keating BJ, Wassel CL, Cushman M, Wilson JG, Gross MD, Tracy RP, Rich SS, Reiner AP, ... ... Lange LA, et al. Genome-wide association study of homocysteine in African Americans from the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Coronary Artery Risk in Young Adults study. Journal of Human Genetics. PMID 29321517 DOI: 10.1038/S10038-017-0384-9  0.489
2018 Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, ... ... Lange LA, et al. Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics. 50: 26-41. PMID 29273807 DOI: 10.1038/S41588-017-0011-X  0.636
2017 Olson NC, Raffield LM, Lange LA, Lange EM, Longstreth WT, Chauhan G, Debette S, Seshadri S, Reiner AP, Tracy RP. Associations of activated coagulation factor VII and factor VIIa-antithrombin levels with genome-wide polymorphisms and cardiovascular disease risk. Journal of Thrombosis and Haemostasis : Jth. PMID 29112333 DOI: 10.1111/Jth.13899  0.36
2017 Raghavan S, Zhang W, Yang IV, Lange LA, Lange EM, Fingerlin TE, Dabelea D. Association between gestational diabetes mellitus exposure and childhood adiposity is not substantially explained by offspring genetic risk of obesity. Diabetic Medicine : a Journal of the British Diabetic Association. PMID 29048747 DOI: 10.1111/Dme.13529  0.354
2017 Joshi PK, Pirastu N, Kentistou KA, Fischer K, Hofer E, Schraut KE, Clark DW, Nutile T, Barnes CLK, Timmers PRHJ, Shen X, Gandin I, McDaid AF, Hansen TF, Gordon SD, ... ... Lange LA, et al. Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity. Nature Communications. 8: 910. PMID 29030599 DOI: 10.1038/S41467-017-00934-5  0.613
2017 Raffield LM, Zakai NA, Duan Q, Laurie C, Smith JD, Irvin MR, Doyle MF, Naik RP, Song C, Manichaikul AW, Liu Y, Durda P, Rotter JI, Jenny NS, Rich SS, ... ... Lange LA, et al. D-Dimer in African Americans: Whole Genome Sequence Analysis and Relationship to Cardiovascular Disease Risk in the Jackson Heart Study. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28912365 DOI: 10.1161/Atvbaha.117.310073  0.325
2017 Sofer T, Wong Q, Hartwig FP, Taylor K, Warren HR, Evangelou E, Cabrera CP, Levy D, Kramer H, Lange LA, Horta BL, Kerr KF, Reiner AP, Franceschini N. Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos. Scientific Reports. 7: 10348. PMID 28871152 DOI: 10.1038/S41598-017-09019-1  0.45
2017 Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A, Dale C, Dudek S, Furlong CE, Gaunt TR, Kim DS, ... ... Lange LA, et al. Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals. Biodata Mining. 10: 25. PMID 28770004 DOI: 10.1186/S13040-017-0145-5  0.345
2017 Kent ST, Rosenson RS, Avery CL, Chen YI, Correa A, Cummings SR, Cupples LA, Cushman M, Evans DS, Gudnason V, Harris TB, Howard G, Irvin MR, Judd SE, Jukema JW, ... Lange L, et al. PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites. Circulation. Cardiovascular Genetics. 10: e001632. PMID 28768753 DOI: 10.1161/Circgenetics.116.001632  0.339
2017 Seyerle AA, Sitlani CM, Noordam R, Gogarten SM, Li J, Li X, Evans DS, Sun F, Laaksonen MA, Isaacs A, Kristiansson K, Highland HM, Stewart JD, Harris TB, Trompet S, ... ... Lange LA, et al. Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology. The Pharmacogenomics Journal. PMID 28719597 DOI: 10.1038/Tpj.2017.10  0.469
2017 Kerr KF, Avery CL, Lin HJ, Raffield LM, Zhang QS, Browning BL, Browning SR, Conomos MP, Gogarten SM, Laurie CC, Sofer T, Thornton TA, Hohensee C, Jackson RD, Kooperberg C, ... ... Lange LA, et al. Genome-wide Association Study of Heart Rate and Its Variability in Hispanic/Latino Cohorts. Heart Rhythm. PMID 28610988 DOI: 10.1016/J.Hrthm.2017.06.018  0.355
2017 Ng MCY, Graff M, Lu Y, Justice AE, Mudgal P, Liu CT, Young K, Yanek LR, Feitosa MF, Wojczynski MK, Rand K, Brody JA, Cade BE, Dimitrov L, Duan Q, ... ... Lange LA, et al. Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African ancestry anthropometry genetics consortium. Plos Genetics. 13: e1006719. PMID 28430825 DOI: 10.1371/Journal.Pgen.1006719  0.493
2017 Raffield LM, Louie T, Sofer T, Jain D, Ipp E, Taylor KD, Papanicolaou GJ, Avilés-Santa L, Lange LA, Laurie CC, Conomos MP, Thornton TA, Ida Chen YD, Qi Q, Cotler S, et al. Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): Potential genomic intersection of iron and glucose regulation? Human Molecular Genetics. PMID 28334935 DOI: 10.1093/Hmg/Ddx082  0.344
2017 Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM, Rüeger S, Thorleifsson G, Justice AE, Lamparter D, Stirrups KE, ... ... Lange LA, et al. Rare and low-frequency coding variants alter human adult height. Nature. PMID 28146470 DOI: 10.1038/Nature21039  0.446
2016 Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR, Sun F, Evans DS, Li X, Li J, Smith AV, Bis JC, Brody JA, ... ... Lange LA, et al. A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Journal of Medical Genetics. PMID 28039329 DOI: 10.1136/Jmedgenet-2016-104112  0.391
2016 Graff M, North KE, Richardson AS, Young KL, Mazul AL, Highland HM, Mohlke KL, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. BMI loci and longitudinal BMI from adolescence to young adulthood in an ethnically diverse cohort. International Journal of Obesity (2005). PMID 28025578 DOI: 10.1038/Ijo.2016.233  0.323
2016 van Rooij FJ, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang LC, Schmidt H, Yang ML, Chen MH, Hayes J, Johnson AD, Yanek LR, Mueller C, ... Lange L, et al. Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. American Journal of Human Genetics. PMID 28017375 DOI: 10.1016/J.Ajhg.2016.11.016  0.462
2016 Floyd JS, Sitlani CM, Avery CL, Noordam R, Li X, Smith AV, Gogarten SM, Li J, Broer L, Evans DS, Trompet S, Brody JA, Stewart JD, Eicher JD, Seyerle AA, ... ... Lange LA, et al. Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group. The Pharmacogenomics Journal. PMID 27958378 DOI: 10.1038/Tpj.2016.90  0.456
2016 Chu AY, Deng X, Fisher VA, Drong A, Zhang Y, Feitosa MF, Liu CT, Weeks O, Choh AC, Duan Q, Dyer TD, Eicher JD, Guo X, Heard-Costa NL, Kacprowski T, ... ... Lange LA, et al. Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Nature Genetics. PMID 27918534 DOI: 10.1038/Ng.3738  0.636
2016 Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, Hartwig FP, Horta BL, Hyppönen E, Power C, Moldovan M, van Iperen E, Hovingh GK, Demuth I, Norman K, ... ... Lange LA, et al. PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study. The Lancet. Diabetes & Endocrinology. PMID 27908689 DOI: 10.1016/S2213-8587(16)30396-5  0.363
2016 De R, Verma SS, Holzinger E, Hall M, Burt A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ, Lange LA, Lanktree MB, Larson EB, North KE, Reiner AP, et al. Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts. Human Genetics. PMID 27848076 DOI: 10.1007/S00439-016-1738-7  0.429
2016 Graff M, Richardson AS, Young KL, Mazul AL, Highland H, North KE, Mohlke KL, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. The interaction between physical activity and obesity gene variants in association with BMI: Does the obesogenic environment matter? Health & Place. 42: 159-165. PMID 27771443 DOI: 10.1016/J.Healthplace.2016.09.003  0.351
2016 Mathias RA, Taub MA, Gignoux CR, Fu W, Musharoff S, O'Connor TD, Vergara C, Torgerson DG, Pino-Yanes M, Shringarpure SS, Huang L, Rafaels N, Boorgula MP, Johnston HR, Ortega VE, ... ... Lange LA, et al. A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications. 7: 12522. PMID 27725671 DOI: 10.1038/Ncomms12522  0.399
2016 Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 785. PMID 27588453 DOI: 10.1016/J.Ajhg.2016.08.002  0.387
2016 Lange LA, Graff M, Lange EM, Young KL, Richardson AS, Mohlke KL, North KE, Harris KM, Gordon-Larsen P. Evidence for Association between SH2B1 Gene Variants and Glycated Hemoglobin in Nondiabetic European American Young Adults: The Add Health Study. Annals of Human Genetics. 80: 294-305. PMID 27530450 DOI: 10.1111/Ahg.12165  0.424
2016 Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen MH, Auer PL, Floyd JS, Huang J, Lange L, van Rooij FJ, Gibbs RA, Metcalf G, Muzny D, et al. Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. American Journal of Human Genetics. 99: 481-488. PMID 27486782 DOI: 10.1016/J.Ajhg.2016.06.016  0.42
2016 Peloso GM, Lange LA, Varga TV, Nickerson DA, Smith JD, Griswold ME, Musani S, Polfus LM, Mei H, Gabriel S, Quarells RC, Altshuler D, Boerwinkle E, Daly MJ, Neale B, et al. Association of Exome Sequences with Cardiovascular Traits among African Americans in the Jackson Heart Study. Circulation. Cardiovascular Genetics. PMID 27422940 DOI: 10.1161/Circgenetics.116.001410  0.448
2016 Tajuddin SM, Schick UM, Eicher JD, Chami N, Giri A, Brody JA, Hill WD, Kacprowski T, Li J, Lyytikäinen LP, Manichaikul A, Mihailov E, O'Donoghue ML, Pankratz N, Pazoki R, ... ... Lange LA, et al. Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. American Journal of Human Genetics. PMID 27346689 DOI: 10.1016/J.Ajhg.2016.05.003  0.417
2016 Eicher JD, Chami N, Kacprowski T, Nomura A, Chen MH, Yanek LR, Tajuddin SM, Schick UM, Slater AJ, Pankratz N, Polfus L, Schurmann C, Giri A, Brody JA, Lange LA, et al. Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. American Journal of Human Genetics. PMID 27346686 DOI: 10.1016/J.Ajhg.2016.05.005  0.394
2016 Chami N, Chen MH, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A, Giri A, Lessard S, Brody JA, Schurmann C, Pankratz N, ... ... Lange LA, et al. Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. American Journal of Human Genetics. PMID 27346685 DOI: 10.1016/J.Ajhg.2016.05.007  0.479
2016 Liu CT, Raghavan S, Maruthur N, Kabagambe EK, Hong J, Ng MC, Hivert MF, Lu Y, An P, Bentley AR, Drolet AM, Gaulton KJ, Guo X, Armstrong LL, Irvin MR, ... ... Lange LA, et al. Trans-ethnic Meta-Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. American Journal of Human Genetics. PMID 27321945 DOI: 10.1016/J.Ajhg.2016.05.006  0.641
2016 Sajuthi SP, Sharma NK, Chou JW, Palmer ND, McWilliams DR, Beal J, Comeau ME, Ma L, Calles-Escandon J, Demons J, Rogers S, Cherry K, Menon L, Kouba E, Davis D, ... ... Lange LA, et al. Mapping adipose and muscle tissue expression quantitative trait loci in African Americans to identify genes for type 2 diabetes and obesity. Human Genetics. PMID 27193597 DOI: 10.1007/S00439-016-1680-8  0.402
2016 Leusink M, Maitland-van der Zee AH, Ding B, Drenos F, van Iperen EP, Warren HR, Caulfield MJ, Cupples LA, Cushman M, Hingorani AD, Hoogeveen RC, Hovingh GK, Kumari M, Lange LA, Munroe PB, et al. A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering. Pharmacogenomics. PMID 27045730 DOI: 10.2217/Pgs.16.8  0.397
2016 van Leeuwen EM, Sabo A, Bis JC, Huffman JE, Manichaikul A, Smith AV, Feitosa MF, Demissie S, Joshi PK, Duan Q, Marten J, van Klinken JB, Surakka I, Nolte IM, Zhang W, ... ... Lange LA, et al. Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. Journal of Medical Genetics. PMID 27036123 DOI: 10.1136/Jmedgenet-2015-103439  0.462
2016 Kan M, Auer PL, Wang GT, Bucasas KL, Hooker S, Rodriguez A, Li B, Ellis J, Adrienne Cupples L, Ida Chen YD, Dupuis J, Fox CS, Gross MD, Smith JD, Heard-Costa N, ... ... Lange LA, et al. Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project. European Journal of Human Genetics : Ejhg. PMID 26757982 DOI: 10.1038/Ejhg.2015.272  0.484
2015 Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, ... ... Lange LA, et al. Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. Nature Communications. 6: 10257. PMID 26674845 DOI: 10.1038/Ncomms10257  0.338
2015 Young KL, Graff M, North KE, Richardson AS, Mohlke KL, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. Interaction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult Health. Bmc Genetics. 16: 131. PMID 26537541 DOI: 10.1186/S12863-015-0289-6  0.35
2015 Bis JC, Sitlani C, Irvin R, Avery CL, Smith AV, Sun F, Evans DS, Musani SK, Li X, Trompet S, Krijthe BP, Harris TB, Quibrera PM, Brody JA, Demissie S, ... ... Lange LA, et al. Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium. Plos One. 10: e0140496. PMID 26516778 DOI: 10.1371/Journal.Pone.0140496  0.437
2015 Li J, Lange LA, Sabourin J, Duan Q, Valdar W, Willis MS, Li Y, Wilson JG, Lange EM. Genome- and exome-wide association study of serum lipoprotein (a) in the Jackson Heart Study. Journal of Human Genetics. PMID 26377243 DOI: 10.1038/Jhg.2015.107  0.444
2015 Durda P, Sabourin J, Lange EM, Nalls MA, Mychaleckyj JC, Jenny NS, Li J, Walston J, Harris TB, Psaty BM, Valdar W, Liu Y, Cushman M, Reiner AP, Tracy RP, ... Lange LA, et al. Plasma Levels of Soluble IL-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 26293465 DOI: 10.1161/Atvbaha.115.305289  0.318
2015 Olson NC, Butenas S, Lange LA, Lange EM, Cushman M, Jenny NS, Walston J, Souto JC, Soria JM, Chauhan G, Debette S, Longstreth WT, Seshadri S, Reiner AP, Tracy RP. Coagulation factor XII genetic variation, ex vivo thrombin generation, and stroke risk in the elderly: results from the Cardiovascular Health Study. Journal of Thrombosis and Haemostasis : Jth. 13: 1867-77. PMID 26286125 DOI: 10.1111/Jth.13111  0.325
2015 Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, ... ... Lange LA, et al. Rare coding variants and X-linked loci associated with age at menarche. Nature Communications. 6: 7756. PMID 26239645 DOI: 10.1038/Ncomms8756  0.456
2015 Lanktree MB, Elbers CC, Li Y, Zhang G, Duan Q, Karczewski KJ, Guo Y, Tragante V, North KE, Cushman M, Asselbergs FW, Wilson JG, Lange LA, Drenos F, Reiner AP, et al. Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration. Journal of Lipid Research. PMID 26199122 DOI: 10.1194/Jlr.P059477  0.478
2015 Auer PL, Nalls M, Meschia JF, Worrall BB, Longstreth WT, Seshadri S, Kooperberg C, Burger KM, Carlson CS, Carty CL, Chen WM, Cupples LA, DeStefano AL, Fornage M, Hardy J, ... ... Lange LA, et al. Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project. Jama Neurology. 72: 781-8. PMID 25961151 DOI: 10.1001/Jamaneurol.2015.0582  0.354
2015 Rodriguez S, Gaunt TR, Guo Y, Zheng J, Barnes MR, Tang W, Danish F, Johnson A, Castillo BA, Li YR, Hakonarson H, Buxbaum SG, Palmer T, Tsai MY, Lange LA, et al. Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array. European Journal of Human Genetics : Ejhg. PMID 25920552 DOI: 10.1038/Ejhg.2015.63  0.45
2015 Young KL, Graff M, North KE, Richardson AS, Bradfield JP, Grant SF, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. Influence of SNP*SNP interaction on BMI in European American adolescents: findings from the National Longitudinal Study of Adolescent Health. Pediatric Obesity. PMID 25893265 DOI: 10.1111/Ijpo.12026  0.358
2015 Tang W, Cushman M, Green D, Rich SS, Lange LA, Yang Q, Tracy RP, Tofler GH, Basu S, Wilson JG, Keating BJ, Weng LC, Taylor HA, Jacobs DR, Delaney JA, et al. Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans. American Journal of Hematology. 90: 534-40. PMID 25779970 DOI: 10.1002/Ajh.24005  0.439
2015 van Leeuwen EM, Karssen LC, Deelen J, Isaacs A, Medina-Gomez C, Mbarek H, Kanterakis A, Trompet S, Postmus I, Verweij N, van Enckevort DJ, Huffman JE, White CC, Feitosa MF, Bartz TM, ... ... Lange LA, et al. Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications. 6: 6065. PMID 25751400 DOI: 10.1038/Ncomms7065  0.341
2015 Lange LA, Willer CJ, Rich SS. Recent developments in genome and exome-wide analyses of plasma lipids. Current Opinion in Lipidology. 26: 96-102. PMID 25692345 DOI: 10.1097/Mol.0000000000000159  0.467
2015 Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, ... ... Lange LA, et al. Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications. 6: 5897. PMID 25631608 DOI: 10.1038/Ncomms6897  0.377
2015 Li J, Shi J, Huang W, Sun J, Wu Y, Duan Q, Luo J, Lange LA, Gordon-Larsen P, Zheng SL, Yuan W, Wang Y, Popkin BM, Mo Z, Xu J, et al. Variant Near FGF5 Has Stronger Effects on Blood Pressure in Chinese With a Higher Body Mass Index. American Journal of Hypertension. 28: 1031-7. PMID 25618516 DOI: 10.1093/Ajh/Hpu263  0.337
2015 Do R, Stitziel NO, Won HH, Jørgensen AB, Duga S, Angelica Merlini P, Kiezun A, Farrall M, Goel A, Zuk O, Guella I, Asselta R, Lange LA, Peloso GM, Auer PL, et al. Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction. Nature. 518: 102-6. PMID 25487149 DOI: 10.1038/Nature13917  0.34
2015 Swerdlow DI, Preiss D, Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T, Sofat R, Stender S, Johnson PC, Scott RA, Leusink M, Verweij N, Sharp SJ, Guo Y, Giambartolomei C, ... ... Lange LA, et al. HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet (London, England). 385: 351-61. PMID 25262344 DOI: 10.1016/S0140-6736(14)61183-1  0.379
2015 Li J, Lange LA, Duan Q, Lu Y, Singleton AB, Zonderman AB, Evans MK, Li Y, Taylor HA, Willis MS, Nalls M, Wilson JG, Lange EM. Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans. Human Molecular Genetics. 24: 572-81. PMID 25224454 DOI: 10.1093/Hmg/Ddu454  0.394
2015 Schick UM, Auer PL, Bis JC, Lin H, Wei P, Pankratz N, Lange LA, Brody J, Stitziel NO, Kim DS, Carlson CS, Fornage M, Haessler J, Hsu L, Jackson RD, et al. Association of exome sequences with plasma C-reactive protein levels in >9000 participants. Human Molecular Genetics. 24: 559-71. PMID 25187575 DOI: 10.1093/Hmg/Ddu450  0.487
2015 Holmes MV, Asselbergs FW, Palmer TM, Drenos F, Lanktree MB, Nelson CP, Dale CE, Padmanabhan S, Finan C, Swerdlow DI, Tragante V, van Iperen EP, Sivapalaratnam S, Shah S, Elbers CC, ... ... Lange LA, et al. Mendelian randomization of blood lipids for coronary heart disease. European Heart Journal. 36: 539-50. PMID 24474739 DOI: 10.1093/Eurheartj/Eht571  0.412
2015 Freitag D, Butterworth AS, Willeit P, Howson JMM, Burgess S, Kaptoge S, Young R, Ho WK, Wood AM, Sweeting M, Spackman S, Staley JR, Ramond A, Harshfield E, Nielsen SF, ... ... Lange LA, et al. Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A Mendelian randomisation analysis The Lancet Diabetes and Endocrinology. 3: 243-253. DOI: 10.1016/S2213-8587(15)00034-0  0.359
2014 Huang KC, Sun W, Wu Y, Chen M, Mohlke KL, Lange LA, Li Y. Association studies with imputed variants using expectation-maximization likelihood-ratio tests. Plos One. 9: e110679. PMID 25383782 DOI: 10.1371/Journal.Pone.0110679  0.341
2014 Barrie ES, Weinshenker D, Verma A, Pendergrass SA, Lange LA, Ritchie MD, Wilson JG, Kuivaniemi H, Tromp G, Carey DJ, Gerhard GS, Brilliant MH, Hebbring SJ, Cubells JF, Pinsonneault JK, et al. Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity. Circulation Research. 115: 1017-25. PMID 25326128 DOI: 10.1161/Circresaha.116.304398  0.301
2014 Du M, Auer PL, Jiao S, Haessler J, Altshuler D, Boerwinkle E, Carlson CS, Carty CL, Chen YD, Curtis K, Franceschini N, Hsu L, Jackson R, Lange LA, Lettre G, et al. Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans. Human Molecular Genetics. 23: 6607-15. PMID 25027330 DOI: 10.1093/Hmg/Ddu361  0.464
2014 Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A, Cavadino A, Drogan D, Padmanabhan S, Li S, Yesupriya A, ... ... Lange LA, et al. Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. Bmj (Clinical Research Ed.). 349: g4164. PMID 25011450 DOI: 10.1136/Bmj.G4164  0.388
2014 Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD, Feitosa MF, Tekola-Ayele F, Chu AY, Nolte IM, Dastani Z, ... ... Lange L, et al. Pleiotropic genes for metabolic syndrome and inflammation. Molecular Genetics and Metabolism. 112: 317-38. PMID 24981077 DOI: 10.1016/J.Ymgme.2014.04.007  0.432
2014 Magnani JW, Brody JA, Prins BP, Arking DE, Lin H, Yin X, Liu CT, Morrison AC, Zhang F, Spector TD, Alonso A, Bis JC, Heckbert SR, Lumley T, Sitlani CM, ... ... Lange LA, et al. Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Circulation. Cardiovascular Genetics. 7: 365-73. PMID 24951663 DOI: 10.1161/Circgenetics.113.000098  0.373
2014 Crosby J, Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y, Tang ZZ, Zhang H, Hindy G, Masca N, Stirrups K, Kanoni S, Do R, et al. Loss-of-function mutations in APOC3, triglycerides, and coronary disease. The New England Journal of Medicine. 371: 22-31. PMID 24941081 DOI: 10.1056/Nejmoa1307095  0.332
2014 Loth DW, Artigas MS, Gharib SA, Wain LV, Franceschini N, Koch B, Pottinger TD, Smith AV, Duan Q, Oldmeadow C, Lee MK, Strachan DP, James AL, Huffman JE, Vitart V, ... ... Lange LA, et al. Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature Genetics. 46: 669-77. PMID 24929828 DOI: 10.1038/Ng.3011  0.388
2014 Ellis J, Lange EM, Li J, Dupuis J, Baumert J, Walston JD, Keating BJ, Durda P, Fox ER, Palmer CD, Meng YA, Young T, Farlow DN, Schnabel RB, Marzi CS, ... ... Lange LA, et al. Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans. Human Genetics. 133: 985-95. PMID 24643644 DOI: 10.1007/S00439-014-1439-Z  0.453
2014 Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang ZZ, Bizon C, Lange EM, Smith JD, Turner EH, Jun G, Kang HM, Peloso G, Auer P, Li KP, et al. Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. American Journal of Human Genetics. 94: 233-45. PMID 24507775 DOI: 10.1016/J.Ajhg.2014.01.010  0.433
2014 Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M, Isaacs A, Jakobsdottir J, Feitosa MF, Davies G, Huffman JE, ... ... Lange LA, et al. Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. American Journal of Human Genetics. 94: 223-32. PMID 24507774 DOI: 10.1016/J.Ajhg.2014.01.009  0.394
2014 Logsdon BA, Dai JY, Auer PL, Johnsen JM, Ganesh SK, Smith NL, Wilson JG, Tracy RP, Lange LA, Jiao S, Rich SS, Lettre G, Carlson CS, Jackson RD, O'Donnell CJ, et al. A variational Bayes discrete mixture test for rare variant association. Genetic Epidemiology. 38: 21-30. PMID 24482836 DOI: 10.1002/Gepi.21772  0.424
2014 Holmes MV, Lange LA, Palmer T, Lanktree MB, North KE, Almoguera B, Buxbaum S, Chandrupatla HR, Elbers CC, Guo Y, Hoogeveen RC, Li J, Li YR, Swerdlow DI, Cushman M, et al. Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis. American Journal of Human Genetics. 94: 198-208. PMID 24462370 DOI: 10.1016/J.Ajhg.2013.12.014  0.383
2014 Yoneyama S, Guo Y, Lanktree MB, Barnes MR, Elbers CC, Karczewski KJ, Padmanabhan S, Bauer F, Baumert J, Beitelshees A, Berenson GS, Boer JM, Burke G, Cade B, Chen W, ... ... Lange LA, et al. Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations. Human Molecular Genetics. 23: 2498-510. PMID 24345515 DOI: 10.1093/Hmg/Ddt626  0.434
2014 Matteini AM, Li J, Lange EM, Tanaka T, Lange LA, Tracy RP, Wang Y, Biggs ML, Arking DE, Fallin MD, Chakravarti A, Psaty BM, Bandinelli S, Ferrucci L, Reiner AP, et al. Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults. Cytokine. 65: 10-6. PMID 24182552 DOI: 10.1016/J.Cyto.2013.10.002  0.343
2014 Richardson AS, North KE, Graff M, Young KM, Mohlke KL, Lange LA, Lange EM, Harris KM, Gordon-Larsen P. Moderate to vigorous physical activity interactions with genetic variants and body mass index in a large US ethnically diverse cohort. Pediatric Obesity. 9: e35-46. PMID 23529959 DOI: 10.1111/J.2047-6310.2013.00152.X  0.389
2013 Liu CT, Monda KL, Taylor KC, Lange L, Demerath EW, Palmas W, Wojczynski MK, Ellis JC, Vitolins MZ, Liu S, Papanicolaou GJ, Irvin MR, Xue L, Griffin PJ, Nalls MA, et al. Genome-wide association of body fat distribution in African ancestry populations suggests new loci. Plos Genetics. 9: e1003681. PMID 23966867 DOI: 10.1371/Journal.Pgen.1003681  0.658
2013 Duan Q, Liu EY, Auer PL, Zhang G, Lange EM, Jun G, Bizon C, Jiao S, Buyske S, Franceschini N, Carlson CS, Hsu L, Reiner AP, Peters U, Haessler J, ... ... Lange LA, et al. Imputation of coding variants in African Americans: better performance using data from the exome sequencing project. Bioinformatics (Oxford, England). 29: 2744-9. PMID 23956302 DOI: 10.1093/Bioinformatics/Btt477  0.337
2013 Wojczynski MK, Li M, Bielak LF, Kerr KF, Reiner AP, Wong ND, Yanek LR, Qu L, White CC, Lange LA, Ferguson JF, He J, Young T, Mosley TH, Smith JA, et al. Genetics of coronary artery calcification among African Americans, a meta-analysis. Bmc Medical Genetics. 14: 75. PMID 23870195 DOI: 10.1186/1471-2350-14-75  0.66
2013 Croteau-Chonka DC, Lange LA, Lee NR, Adair LS, Mohlke KL. Replication of LIN28B SNP association with age of menarche in young Filipino women. Pediatric Obesity. 8: e50-3. PMID 23740805 DOI: 10.1111/J.2047-6310.2013.00178.X  0.41
2013 Reiner AP, Hartiala J, Zeller T, Bis JC, Dupuis J, Fornage M, Baumert J, Kleber ME, Wild PS, Baldus S, Bielinski SJ, Fontes JD, Illig T, Keating BJ, Lange LA, et al. Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia. Human Molecular Genetics. 22: 3381-93. PMID 23620142 DOI: 10.1093/Hmg/Ddt189  0.472
2013 Monda KL, Chen GK, Taylor KC, Palmer C, Edwards TL, Lange LA, Ng MC, Adeyemo AA, Allison MA, Bielak LF, Chen G, Graff M, Irvin MR, Rhie SK, Li G, et al. A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nature Genetics. 45: 690-6. PMID 23583978 DOI: 10.1038/Ng.2608  0.738
2013 Chen Z, Tang H, Qayyum R, Schick UM, Nalls MA, Handsaker R, Li J, Lu Y, Yanek LR, Keating B, Meng Y, van Rooij FJ, Okada Y, Kubo M, Rasmussen-Torvik L, ... ... Lange L, et al. Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. Human Molecular Genetics. 22: 2529-38. PMID 23446634 DOI: 10.1093/Hmg/Ddt087  0.494
2013 Mao X, Li Y, Liu Y, Lange L, Li M. Testing genetic association with rare variants in admixed populations. Genetic Epidemiology. 37: 38-47. PMID 23032398 DOI: 10.1002/Gepi.21687  0.395
2013 Guo Y, Lanktree MB, Taylor KC, Hakonarson H, Lange LA, Keating BJ, Fairfax BP, Elbers CC, Barnard J, Farrall M, Padmanabhan S, Baumert J, Castillo BA, Gaunt TR, Gong Y, et al. Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals Human Molecular Genetics. 22: 184-201. PMID 23001569 DOI: 10.1093/Hmg/Dds396  0.454
2012 Graff M, North KE, Mohlke KL, Lange LA, Luo J, Harris KM, Young KL, Richardson AS, Lange EM, Gordon-Larsen P. Estimation of genetic effects on BMI during adolescence in an ethnically diverse cohort: The National Longitudinal Study of Adolescent Health. Nutrition & Diabetes. 2: e47. PMID 23168566 DOI: 10.1038/Nutd.2012.20  0.327
2012 Auer PL, Johnsen JM, Johnson AD, Logsdon BA, Lange LA, Nalls MA, Zhang G, Franceschini N, Fox K, Lange EM, Rich SS, O'Donnell CJ, Jackson RD, Wallace RB, Chen Z, et al. Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project. American Journal of Human Genetics. 91: 794-808. PMID 23103231 DOI: 10.1016/J.Ajhg.2012.08.031  0.457
2012 Asselbergs FW, Guo Y, van Iperen EP, Sivapalaratnam S, Tragante V, Lanktree MB, Lange LA, Almoguera B, Appelman YE, Barnard J, Baumert J, Beitelshees AL, Bhangale TR, Chen YD, Gaunt TR, et al. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Journal of Human Genetics. 91: 823-38. PMID 23063622 DOI: 10.1016/J.Ajhg.2012.08.032  0.411
2012 Chiang CW, Liu CT, Lettre G, Lange LA, Jorgensen NW, Keating BJ, Vedantam S, Nock NL, Franceschini N, Reiner AP, Demerath EW, Boerwinkle E, Rotter JI, Wilson JG, North KE, et al. Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms. Genetics. 192: 253-66. PMID 22714408 DOI: 10.1534/Genetics.112.141945  0.477
2012 Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, ... ... Lange LA, et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. Plos Genetics. 8: e1002607. PMID 22479202 DOI: 10.1371/Journal.Pgen.1002607  0.411
2012 Qayyum R, Snively BM, Ziv E, Nalls MA, Liu Y, Tang W, Yanek LR, Lange L, Evans MK, Ganesh S, Austin MA, Lettre G, Becker DM, Zonderman AB, Singleton AB, et al. A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans. Plos Genetics. 8: e1002491. PMID 22423221 DOI: 10.1371/Journal.Pgen.1002491  0.377
2012 Croteau-Chonka DC, Wu Y, Li Y, Fogarty MP, Lange LA, Kuzawa CW, McDade TW, Borja JB, Luo J, AbdelBaky O, Combs TP, Adair LS, Lange EM, Mohlke KL. Population-specific coding variant underlies genome-wide association with adiponectin level. Human Molecular Genetics. 21: 463-71. PMID 22010046 DOI: 10.1093/Hmg/Ddr480  0.438
2012 Wu Y, McDade TW, Kuzawa CW, Borja J, Li Y, Adair LS, Mohlke KL, Lange LA. Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment. Inflammation. 35: 574-83. PMID 21647738 DOI: 10.1007/S10753-011-9348-Y  0.468
2012 Lanktree M, Guo Y, Murtaza M, Glessner J, Bailey S, Onland-Moret N, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson C, Klopp N, Baumert J, Padmanabhan S, ... ... Lange L, et al. Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height The American Journal of Human Genetics. 90: 1116-1117. DOI: 10.1016/J.Ajhg.2012.05.017  0.428
2011 Curocichin G, Wu Y, McDade TW, Kuzawa CW, Borja JB, Qin L, Lange EM, Adair LS, Lange LA, Mohlke KL. Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults. Journal of Human Genetics. 56: 823-7. PMID 21937998 DOI: 10.1038/Jhg.2011.106  0.467
2011 Bhatia G, Patterson N, Pasaniuc B, Zaitlen N, Genovese G, Pollack S, Mallick S, Myers S, Tandon A, Spencer C, Palmer CD, Adeyemo AA, Akylbekova EL, Cupples LA, Divers J, ... ... Lange L, et al. Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. American Journal of Human Genetics. 89: 368-81. PMID 21907010 DOI: 10.1016/J.Ajhg.2011.07.025  0.377
2011 Reiner AP, Lettre G, Nalls MA, Ganesh SK, Mathias R, Austin MA, Dean E, Arepalli S, Britton A, Chen Z, Couper D, Curb JD, Eaton CB, Fornage M, Grant SF, ... ... Lange LA, et al. Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). Plos Genetics. 7: e1002108. PMID 21738479 DOI: 10.1371/Journal.Pgen.1002108  0.395
2011 Taylor KC, Lange LA, Zabaneh D, Lange E, Keating BJ, Tang W, Smith NL, Delaney JA, Kumari M, Hingorani A, North KE, Kivimaki M, Tracy RP, O'Donnell CJ, Folsom AR, et al. A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium. Human Molecular Genetics. 20: 3525-34. PMID 21676895 DOI: 10.1093/Hmg/Ddr264  0.476
2011 Pasaniuc B, Zaitlen N, Lettre G, Chen GK, Tandon A, Kao WH, Ruczinski I, Fornage M, Siscovick DS, Zhu X, Larkin E, Lange LA, Cupples LA, Yang Q, Akylbekova EL, et al. Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. Plos Genetics. 7: e1001371. PMID 21541012 DOI: 10.1371/Journal.Pgen.1001371  0.41
2011 Bielinski SJ, Reiner AP, Nickerson D, Carlson C, Bailey KR, Thyagarajan B, Lange LA, Boerwinkle EA, Jacobs DR, Gross MD. Polymorphisms in the ICAM1 gene predict circulating soluble intercellular adhesion molecule-1(sICAM-1). Atherosclerosis. 216: 390-4. PMID 21392767 DOI: 10.1016/J.Atherosclerosis.2011.02.018  0.355
2011 Graff M, North KE, Monda KL, Lange EM, Lange LA, Guo G, Gordon-Larsen P. The combined influence of genetic factors and sedentary activity on body mass changes from adolescence to young adulthood: the National Longitudinal Adolescent Health Study. Diabetes/Metabolism Research and Reviews. 27: 63-9. PMID 21218509 DOI: 10.1002/Dmrr.1147  0.305
2011 Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, ... ... Lange LA, et al. Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. American Journal of Human Genetics. 88: 6-18. PMID 21194676 DOI: 10.1016/J.Ajhg.2010.11.007  0.511
2011 Lo KS, Wilson JG, Lange LA, Folsom AR, Galarneau G, Ganesh SK, Grant SF, Keating BJ, McCarroll SA, Mohler ER, O'Donnell CJ, Palmas W, Tang W, Tracy RP, Reiner AP, et al. Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans. Human Genetics. 129: 307-17. PMID 21153663 DOI: 10.1007/S00439-010-0925-1  0.458
2011 Wassel CL, Lange LA, Keating BJ, Taylor KC, Johnson AD, Palmer C, Ho LA, Smith NL, Lange EM, Li Y, Yang Q, Delaney JA, Tang W, Tofler G, Redline S, et al. Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe). Blood. 117: 268-75. PMID 20978265 DOI: 10.1182/Blood-2010-06-289546  0.499
2011 Croteau-Chonka DC, Marvelle AF, Lange EM, Lee NR, Adair LS, Lange LA, Mohlke KL. Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women. Obesity (Silver Spring, Md.). 19: 1019-27. PMID 20966902 DOI: 10.1038/Oby.2010.256  0.488
2010 Wu Y, Li Y, Lange EM, Croteau-Chonka DC, Kuzawa CW, McDade TW, Qin L, Curocichin G, Borja JB, Lange LA, Adair LS, Mohlke KL. Genome-wide association study for adiponectin levels in Filipino women identifies CDH13 and a novel uncommon haplotype at KNG1-ADIPOQ. Human Molecular Genetics. 19: 4955-64. PMID 20876611 DOI: 10.1093/Hmg/Ddq423  0.471
2010 Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, ... ... Lange LA, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 466: 707-13. PMID 20686565 DOI: 10.1038/Nature09270  0.433
2010 Burgess S, Thompson SG, Burgess S, Thompson SG, Andrews G, Samani NJ, Hall A, Whincup P, Morris R, Lawlor DA, Davey Smith G, Timpson N, Ebrahim S, Ben-Shlomo Y, ... ... Lange L, et al. Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables. Statistics in Medicine. 29: 1298-311. PMID 20209660 DOI: 10.1002/Sim.3843  0.354
2010 Lange LA, Croteau-Chonka DC, Marvelle AF, Qin L, Gaulton KJ, Kuzawa CW, McDade TW, Wang Y, Li Y, Levy S, Borja JB, Lange EM, Adair LS, Mohlke KL. Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults. Human Molecular Genetics. 19: 2050-8. PMID 20154341 DOI: 10.1093/Hmg/Ddq062  0.449
2010 Carty CL, Heagerty P, Heckbert SR, Jarvik GP, Lange LA, Cushman M, Tracy RP, Reiner AP. Interaction between fibrinogen and IL-6 genetic variants and associations with cardiovascular disease risk in the Cardiovascular Health Study. Annals of Human Genetics. 74: 1-10. PMID 20059469 DOI: 10.1111/J.1469-1809.2009.00551.X  0.375
2010 North KE, Graff M, Adair LS, Lange EM, Lange LA, Guo G, Gordon-Larsen P. Genetic epidemiology of BMI and body mass change from adolescence to young adulthood. Obesity (Silver Spring, Md.). 18: 1474-6. PMID 19851309 DOI: 10.1038/Oby.2009.350  0.328
2010 Tang W, Cushman M, Basu S, Green D, Reiner AP, Delaney JA, Lange LA, Smith NL, Tracy RP, Wilson JG, Tofler G, Yang Q, Keating BJ, Taylor H, Jacobs D, et al. Gene-Centric Approach Identifies New and Known Loci for Factor VIII Activity and Von Willebrand Factor Antigen In the Candidate Gene Association Resource (CARe) Consortium Blood. 116: 806-806. DOI: 10.1182/Blood.V116.21.806.806  0.442
2009 Reiner AP, Gross MD, Carlson CS, Bielinski SJ, Lange LA, Fornage M, Jenny NS, Walston J, Tracy RP, Williams OD, Jacobs DR, Nickerson DA. Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiovascular Health Study. Circulation. Cardiovascular Genetics. 2: 244-54. PMID 20031592 DOI: 10.1161/Circgenetics.108.839506  0.366
2009 Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, ... ... Lange LA, et al. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? Plos Genetics. 5: e1000694. PMID 19851442 DOI: 10.1371/Journal.Pgen.1000694  0.39
2009 Smith NL, Wiggins KL, Reiner AP, Lange LA, Cushman M, Heckbert SR, Lumley T, Rice KM, Folsom AR, Psaty BM. Replication of findings on the association of genetic variation in 24 hemostasis genes and risk of incident venous thrombosis. Journal of Thrombosis and Haemostasis : Jth. 7: 1743-6. PMID 19682239 DOI: 10.1111/J.1538-7836.2009.03567.X  0.441
2009 Reiner AP, Lange LA, Smith NL, Zakai NA, Cushman M, Folsom AR. Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study Journal of Thrombosis and Haemostasis. 7: 1499-1505. PMID 19552680 DOI: 10.1111/J.1538-7836.2009.03522.X  0.437
2009 Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR, Kooperberg C, LaCroix A, Tracy RP, Atzmon G, Lange EM, et al. Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults. Experimental Gerontology. 44: 350-5. PMID 19249341 DOI: 10.1016/J.Exger.2009.02.004  0.407
2008 Smith AK, Lange LA, Ampleford EJ, Meyers DA, Bleecker ER, Howard TD. Association of polymorphisms in CASP10 and CASP8 with FEV(1)/FVC and bronchial hyperresponsiveness in ethnically diverse asthmatics. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 38: 1738-44. PMID 18823309 DOI: 10.1111/J.1365-2222.2008.03095.X  0.386
2008 Lange EM, Sun J, Lange LA, Zheng SL, Duggan D, Carpten JD, Gronberg H, Isaacs WB, Xu J, Chang BL. Family-based samples can play an important role in genetic association studies. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 17: 2208-14. PMID 18768484 DOI: 10.1158/1055-9965.Epi-08-0183  0.45
2008 Reiner AP, Carty CL, Jenny NS, Nievergelt C, Cushman M, Stearns-Kurosawa DJ, Kurosawa S, Kuller LH, Lange LA. PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study. Journal of Thrombosis and Haemostasis. 6: 1625-1632. PMID 18680534 DOI: 10.1111/J.1538-7836.2008.03118.X  0.411
2008 Reiner AP, Wurfel MM, Lange LA, Carlson CS, Nord AS, Carty CL, Rieder MJ, Desmarais C, Jenny NS, Iribarren C, Walston JD, Williams OD, Nickerson DA, Jarvik GP. Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1407-12. PMID 18451331 DOI: 10.1161/Atvbaha.108.167437  0.307
2008 Reiner AP, Barber MJ, Guan Y, Ridker PM, Lange LA, Chasman DI, Walston JD, Cooper GM, Jenny NS, Rieder MJ, Durda JP, Smith JD, Novembre J, Tracy RP, Rotter JI, et al. Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein. American Journal of Human Genetics. 82: 1193-201. PMID 18439552 DOI: 10.1016/J.Ajhg.2008.03.017  0.414
2008 Marvelle AF, Lange LA, Qin L, Adair LS, Mohlke KL. Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. Diabetes. 57: 1987-91. PMID 18426866 DOI: 10.2337/Db07-1700  0.38
2008 Carty CL, Cushman M, Jones D, Lange LA, Hindorff LA, Rice K, Jenny NS, Durda JP, Walston J, Carlson CS, Nickerson D, Tracy RP, Reiner AP. Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study. Thrombosis and Haemostasis. 99: 388-95. PMID 18278190 DOI: 10.1160/Th07-08-0523  0.447
2008 Campbell DB, Lange LA, Skelly T, Lieberman J, Levitt P, Sullivan PF. Association of RGS2 and RGS5 variants with schizophrenia symptom severity. Schizophrenia Research. 101: 67-75. PMID 18262772 DOI: 10.1016/J.Schres.2008.01.006  0.35
2008 Lange LA, Reiner AP, Carty CL, Jenny NS, Cushman M, Lange EM. Common genetic variants associated with plasma fibrin D-dimer concentration in older European- and African-American adults. Journal of Thrombosis and Haemostasis : Jth. 6: 654-9. PMID 18208536 DOI: 10.1111/J.1538-7836.2008.02906.X  0.334
2008 Sarma AV, Dunn RL, Lange LA, Ray A, Wang Y, Lange EM, Cooney KA. Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study. The Prostate. 68: 296-305. PMID 18163429 DOI: 10.1002/Pros.20696  0.314
2008 Hindorff LA, Rice KM, Lange LA, Diehr P, Halder I, Walston J, Kwok P, Ziv E, Nievergelt C, Cummings SR, Newman AB, Tracy RP, Psaty BM, Reiner AP. Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study. Atherosclerosis. 197: 922-30. PMID 17888441 DOI: 10.1016/J.Atherosclerosis.2007.08.012  0.387
2007 Walston JD, Fallin MD, Cushman M, Lange L, Psaty B, Jenny N, Browner W, Tracy R, Durda P, Reiner A. IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study. Human Genetics. 122: 485-94. PMID 17851695 DOI: 10.1007/S00439-007-0428-X  0.36
2007 Marvelle AF, Lange LA, Qin L, Wang Y, Lange EM, Adair LS, Mohlke KL. Comparison of ENCODE region SNPs between Cebu Filipino and Asian HapMap samples. Journal of Human Genetics. 52: 729-37. PMID 17636361 DOI: 10.1007/S10038-007-0175-9  0.407
2007 Skelly T, Pinheiro AP, Lange LA, Sullivan PF. Is rs7566605, a SNP near INSIG2, associated with body mass in a randomized clinical trial of antipsychotics in schizophrenia? Molecular Psychiatry. 12: 321-2. PMID 17389899 DOI: 10.1038/Sj.Mp.4001956  0.318
2007 Guo G, Tong Y, Xie CW, Lange LA. Dopamine transporter, gender, and number of sexual partners among young adults. European Journal of Human Genetics : Ejhg. 15: 279-87. PMID 17245411 DOI: 10.1038/Sj.Ejhg.5201763  0.319
2007 Sullivan PF, Keefe RS, Lange LA, Lange EM, Stroup TS, Lieberman J, Maness PF. NCAM1 and neurocognition in schizophrenia. Biological Psychiatry. 61: 902-10. PMID 17161382 DOI: 10.1016/J.Biopsych.2006.07.036  0.367
2007 Sarma AV, Lange L, Ray A, Lange E, Dunn RL, Cooney KA. 456: Genetic Polymorphisms in CYP17, CYPJA4, CYP19 and SRD5A2 and Prostate Cancer Risk in African American Men: the Flint Men's Health Study Journal of Urology. 177: 153-153. DOI: 10.1016/S0022-5347(18)30709-2  0.309
2007 Lange LA, Lange EM, Tracy RP, Reine AP. Polymorphisms in the Jama. 297: 1317. DOI: 10.1001/Jama.297.12.1317-B  0.339
2006 Lange LA, Carlson CS, Hindorff LA, Lange EM, Walston J, Durda JP, Cushman M, Bis JC, Zeng D, Lin D, Kuller LH, Nickerson DA, Psaty BM, Tracy RP, Reiner AP. Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events. Jama. 296: 2703-11. PMID 17164456 DOI: 10.1001/Jama.296.22.2703  0.313
2006 Lange LA, Burdon K, Langefeld CD, Liu Y, Beck SR, Rich SS, Freedman BI, Brosnihan KB, Herrington DM, Wagenknecht LE, Bowden DW. Heritability and expression of C-reactive protein in type 2 diabetes in the Diabetes Heart Study. Annals of Human Genetics. 70: 717-25. PMID 17044846 DOI: 10.1111/J.1469-1809.2006.00280.X  0.414
2006 Li T, Lange LA, Li X, Susswein L, Bryant B, Malone R, Lange EM, Huang TY, Stafford DW, Evans JP. Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation. Journal of Medical Genetics. 43: 740-4. PMID 16611750 DOI: 10.1136/Jmg.2005.040410  0.372
2006 Kardia SL, Bielak LF, Lange LA, Cheverud JM, Boerwinkle E, Turner ST, Sheedy PF, Peyser PA. Epistatic effects between two genes in the renin-angiotensin system and systolic blood pressure and coronary artery calcification. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 12: CR150-8. PMID 16572049  0.527
2006 Dijkstra A, Howard TD, Vonk JM, Ampleford EJ, Lange LA, Bleecker ER, Meyers DA, Postma DS. Estrogen receptor 1 polymorphisms are associated with airway hyperresponsiveness and lung function decline, particularly in female subjects with asthma. The Journal of Allergy and Clinical Immunology. 117: 604-11. PMID 16522460 DOI: 10.1016/J.Jaci.2005.11.023  0.344
2006 Lange EM, Ho LA, Beebe-Dimmer JL, Wang Y, Gillanders EM, Trent JM, Lange LA, Wood DP, Cooney KA. Genome-wide linkage scan for prostate cancer susceptibility genes in men with aggressive disease: significant evidence for linkage at chromosome 15q12. Human Genetics. 119: 400-7. PMID 16508751 DOI: 10.1007/S00439-006-0149-6  0.375
2006 Chang BL, Lange EM, Dimitrov L, Valis CJ, Gillanders EM, Lange LA, Wiley KE, Isaacs SD, Wiklund F, Baffoe-Bonnie A, Langefeld CD, Zheng SL, Matikainen MP, Ikonen T, Fredriksson H, et al. Two-locus genome-wide linkage scan for prostate cancer susceptibility genes with an interaction effect. Human Genetics. 118: 716-24. PMID 16328469 DOI: 10.1007/S00439-005-0099-4  0.323
2006 Beebe-Dimmer JL, Lange LA, Cain JE, Lewis RC, Ray AM, Sarma AV, Lange EM, Cooney KA. Polymorphisms in the prostate-specific antigen gene promoter do not predict serum prostate-specific antigen levels in African-American men. Prostate Cancer and Prostatic Diseases. 9: 50-5. PMID 16247489 DOI: 10.1038/Sj.Pcan.4500840  0.316
2006 Bell TA, de la Casa-Esperón E, Doherty HE, Ideraabdullah F, Kim K, Wang Y, Lange LA, Wilhemsen K, Lange EM, Sapienza C, de Villena FP. The paternal gene of the DDK syndrome maps to the Schlafen gene cluster on mouse chromosome 11. Genetics. 172: 411-23. PMID 16172501 DOI: 10.1534/Genetics.105.047118  0.338
2005 Schuckit MA, Wilhelmsen K, Smith TL, Feiler HS, Lind P, Lange LA, Kalmijn J. Autosomal linkage analysis for the level of response to alcohol. Alcoholism, Clinical and Experimental Research. 29: 1976-82. PMID 16340454 DOI: 10.1097/01.Alc.0000187598.82921.27  0.304
2005 Howard TD, Giles WH, Xu J, Wozniak MA, Malarcher AM, Lange LA, Macko RF, Basehore MJ, Meyers DA, Cole JW, Kittner SJ. Promoter polymorphisms in the nitric oxide synthase 3 gene are associated with ischemic stroke susceptibility in young black women. Stroke; a Journal of Cerebral Circulation. 36: 1848-51. PMID 16100023 DOI: 10.1161/01.Str.0000177978.97428.53  0.356
2005 Lange LA, Norris JM, Langefeld CD, Nicklas BJ, Wagenknecht LE, Saad MF, Bowden DW. Association of adipose tissue deposition and beta-2 adrenergic receptor variants: The IRAS family study International Journal of Obesity. 29: 449-457. PMID 15672110 DOI: 10.1038/Sj.Ijo.0802883  0.332
2004 Bento JL, Palmer ND, Mychaleckyj JC, Lange LA, Langefeld CD, Rich SS, Freedman BI, Bowden DW. Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes. Diabetes. 53: 3007-12. PMID 15504984 DOI: 10.2337/Diabetes.53.11.3007  0.425
2004 Basehore MJ, Howard TD, Lange LA, Moore WC, Hawkins GA, Marshik PL, Harkins MS, Meyers DA, Bleecker ER. A comprehensive evaluation of IL4 variants in ethnically diverse populations: association of total serum IgE levels and asthma in white subjects. The Journal of Allergy and Clinical Immunology. 114: 80-7. PMID 15241348 DOI: 10.1016/J.Jaci.2004.05.035  0.404
2003 Bensen JT, Lange LA, Langefeld CD, Chang BL, Bleecker ER, Meyers DA, Xu J. Exploring pleiotropy using principal components. Bmc Genetics. 4: S53. PMID 14975121 DOI: 10.1186/1471-2156-4-S1-S53  0.368
2002 Lange LA, Bowden DW, Langefeld CD, Wagenknecht LE, Carr JJ, Rich SS, Riley WA, Freedman BI. Heritability of carotid artery intima-medial thickness in type 2 diabetes. Stroke; a Journal of Cerebral Circulation. 33: 1876-81. PMID 12105369 DOI: 10.1161/01.Str.0000019909.71547.Aa  0.325
2002 Lange LA, Lange EM, Bielak LF, Langefeld CD, Kardia SL, Royston P, Turner ST, Sheedy PF, Boerwinkle E, Peyser PA. Autosomal genome-wide scan for coronary artery calcification loci in sibships at high risk for hypertension. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 418-23. PMID 11884284 DOI: 10.1161/Hq0302.105721  0.584
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