| Year |
Citation |
Score |
| 2020 |
Hu X, Harvey SE, Zheng R, Lyu J, Grzeskowiak CL, Powell E, Piwnica-Worms H, Scott KL, Cheng C. The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing. Nature Communications. 11: 486. PMID 31980632 DOI: 10.1038/S41467-020-14304-1 |
0.353 |
|
| 2020 |
Cha J, Yang W, Xia W, Wei Y, Chan L, Lim S, Li C, Hsu J, Wang H, Kuo C, Chang W, Hadad S, Purdie C, McCoy A, Litton J, ... ... Piwnica-Worms H, et al. Abstract A16: Metformin is a potential nontoxic adjuvant to enhance the efficacy of non-PDL1/PD-1 targeting immune therapies Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-A16 |
0.301 |
|
| 2020 |
Echeverria GV, Xu M, Shao J, Zhang X, Jeter-Jones S, Zhou X, Moulder SL, Marszalek JR, Heffernan TP, Symmans FW, Chang JT, Piwnica-Worms H. Abstract GS4-02: Investigating genomic and phenotypic evolution of triple negative breast cancer chemoresistance and metastasis in patient-derived xenografts Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Gs4-02 |
0.325 |
|
| 2020 |
Sinha VC, Xu M, Rinkenbaugh AL, Zhou X, Zhang X, Piwnica-Worms H. Abstract 2822: Single-cell evaluation to identify tumor-stroma niches driving the transition from in situ to invasive breast cancer Cancer Research. 80: 2822-2822. DOI: 10.1158/1538-7445.Am2020-2822 |
0.327 |
|
| 2019 |
Yang H, Shu Z, Jiang Y, Mao W, Pang L, Redwood A, Jeter-Jones SL, Jennings NB, Ornelas A, Zhou J, Rodriguez-Aguayo C, Bartholomeusz G, Iles LR, Zacharias NM, Millward SW, ... ... Piwnica-Worms H, et al. 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31391192 DOI: 10.1158/1078-0432.Ccr-18-3448 |
0.371 |
|
| 2019 |
Acharya S, Yao J, Li P, Zhang C, Lowery FJ, Zhang Q, Guo H, Qu J, Yang F, Wistuba II, Piwnica-Worms H, Sahin AA, Yu D. Sphingosine-kinase-1 signaling promotes metastasis of triple-negative breast cancer. Cancer Research. PMID 31239273 DOI: 10.1158/0008-5472.Can-18-3803 |
0.372 |
|
| 2019 |
Li S, Lavagnino Z, Lemacon D, Kong L, Ustione A, Ng X, Zhang Y, Wang Y, Zheng B, Piwnica-Worms H, Vindigni A, Piston DW, You Z. Ca-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection. Molecular Cell. PMID 31053472 DOI: 10.1016/J.Molcel.2019.04.003 |
0.345 |
|
| 2019 |
Echeverria GV, Ge Z, Seth S, Zhang X, Jeter-Jones S, Zhou X, Cai S, Tu Y, McCoy A, Peoples M, Sun Y, Qiu H, Chang Q, Bristow C, Carugo A, ... ... Piwnica-Worms H, et al. Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state. Science Translational Medicine. 11. PMID 30996079 DOI: 10.1126/Scitranslmed.Aav0936 |
0.301 |
|
| 2019 |
Seth S, Huo L, Rauch G, Lau R, Gilcrease M, Adrada B, Piwnica-Worms H, Symmans W, Draetta G, Futreal A, Moulder S, Chang J. Abstract P3-07-01: Towards a therapeutically relevant subtyping scheme for triple-negative breast cancer (TNBC), profiling results from A Randomized, TNBC Enrolling trial to confirm Molecular profiling Improves Survival (ARTEMIS) Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P3-07-01 |
0.309 |
|
| 2019 |
Echeverria G, Ge Z, Seth S, Jeter-Jones S, Zhang X, Zhou X, Cai S, Tu Y, McCoy A, Peoples M, Lau R, Shao J, Sun Y, Bristow C, Carugo A, ... ... Piwnica-Worms H, et al. Abstract GS5-05: Resistance to neoadjuvant chemotherapy in triple negative breast cancer mediated by a reversible drug-tolerant state Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Gs5-05 |
0.326 |
|
| 2019 |
Rinkenbaugh AL, Sinha VC, Zhang X, Shao J, Piwnica-Worms H. Abstract 4708: Investigating triple negative breast cancer phenotypic heterogeneity of human and patient-derived xenograft samples using imaging mass cytometry Cancer Research. 79: 4708-4708. DOI: 10.1158/1538-7445.Am2019-4708 |
0.353 |
|
| 2019 |
Hollander Pd, Shah S, Zhou X, Redwood A, Cai S, Sobieski M, Brunell D, Stephan C, Davies P, Piwnica-Worms H, Moulder S, Symmans WF, Mani SA. Abstract 4669: Overcoming therapy resistance in stem cell-rich triple negative breast cancer through p38 MAP kinase inhibition Cancer Research. 79: 4669-4669. DOI: 10.1158/1538-7445.Am2019-4669 |
0.38 |
|
| 2019 |
Bonilla MdlC, Stemler KM, Jeter-Jones S, Fujimoto TN, Molkentine J, Torres GMA, Taniguchi CM, Piwnica-Worms H. Abstract 3746: Fasting in mice enables abdominal radiation dose escalation in the setting of pancreatic cancer by mitigating small intestinal toxicity Cancer Research. 79: 3746-3746. DOI: 10.1158/1538-7445.Am2019-3746 |
0.314 |
|
| 2018 |
Li AG, Murphy EC, Culhane AC, Powell E, Wang H, Bronson RT, Von T, Giobbie-Hurder A, Gelman RS, Briggs KJ, Piwnica-Worms H, Zhao JJ, Kung AL, Kaelin WG, Livingston DM. BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254159 DOI: 10.1073/Pnas.1807112115 |
0.363 |
|
| 2018 |
Ge Z, Leighton JS, Wang Y, Peng X, Chen Z, Chen H, Sun Y, Yao F, Li J, Zhang H, Liu J, Shriver CD, Hu H, Piwnica-Worms H, et al. Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Reports. 23: 213-226.e3. PMID 29617661 DOI: 10.1016/J.Celrep.2018.03.047 |
0.343 |
|
| 2018 |
Sinha VC, Yang F, Rinkenbaugh AL, Zhou X, Zhang X, Wistuba II, Piwnica-Worms H. Abstract B59: Multiparametric imaging to evaluate human and mouse breast carcinoma in situ Molecular Cancer Research. 16. DOI: 10.1158/1557-3125.Advbc17-B59 |
0.303 |
|
| 2018 |
Redwood A, Seth S, Cai S, Piwnica-Worms H. Abstract P6-06-01: Comprehensive analysis of the DNA damage repair and maintenance pathways that regulate TNBC sensitivity to replication stress Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P6-06-01 |
0.409 |
|
| 2018 |
Bonilla MdlC, Stemler KM, Fujimoto TN, Jeter-Jones S, Molkentine JM, Torres GMA, Taniguchi CM, Piwnica-Worms H. Abstract 4164: Fasting protects mice from lethal radiation by promoting small intestinal stem cell survival Cancer Research. 78: 4164-4164. DOI: 10.1158/1538-7445.Am2018-4164 |
0.315 |
|
| 2018 |
Marszalek JR, Seth S, Corti D, Zhang Q, Echeverria GV, Han L, Sun Y, Molina J, Gera S, Chang E, Khor TO, Mahendra M, Feng N, McAfoos T, Giuliani V, ... ... Piwnica-Worms H, et al. Abstract 2856: Targeting OXPHOS with IACS-010759 to eliminate standard of care resistant tumor cells Cancer Research. 78: 2856-2856. DOI: 10.1158/1538-7445.Am2018-2856 |
0.337 |
|
| 2018 |
Rinkenbaugh AL, Sinha VC, Zhang X, Piwnica-Worms H. Abstract 2181: Functionalizing intratumoral signaling heterogeneity in triple negative breast cancer Cancer Research. 78: 2181-2181. DOI: 10.1158/1538-7445.Am2018-2181 |
0.342 |
|
| 2018 |
Echeverria GV, Seth S, Ge Z, Carugo A, Bristow C, Mundi P, Jeter-Jones S, Zhang X, Zhou X, McCoy A, Cai S, Tu Y, Sun Y, Marszalek J, Califano A, ... ... Piwnica-Worms H, et al. Abstract 212: High-resolution barcoding in patient-derived xenografts of triple-negative breast cancer reveals reversible chemoresistance conferred by non-mutational mechanisms Cancer Research. 78: 212-212. DOI: 10.1158/1538-7445.Am2018-212 |
0.317 |
|
| 2018 |
Sen T, Chen L, Rodriguez BL, Li L, Li Y, Fan Y, Glisson B, Wang J, Piwnica-Worms H, Sage J, Heymach JV, Gibbons DL, Byers LA. Abstract A108: DNA damage repair targeting upregulates PD-L1 level and potentiates the effect of PD-L1 blockade in small cell lung cancer Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A108 |
0.339 |
|
| 2017 |
Gadhikar MA, Zhang J, Shen L, Rao X, Wang J, Zhao M, Kalu NN, Johnson FM, Byers LA, Heymach J, Hittelman WN, Udayakumar D, Pandita RK, Pandita TK, Pickering CR, ... ... Piwnica-Worms H, et al. CDKN2A/p16 deletion in head and neck cancer cells is associated with Cdk2 activation, replication stress, and vulnerability to Chk1 inhibition. Cancer Research. PMID 29229598 DOI: 10.1158/0008-5472.Can-17-2802 |
0.406 |
|
| 2017 |
Sen T, Tong P, Stewart CA, Cristea S, Valliani A, Shames DS, Redwood A, Fan Y, Li L, Glisson BS, Minna J, Sage J, Gibbons DL, Piwnica-Worms H, Heymach J, et al. CHK1 inhibition in small cell lung cancer produces single-agent activity in biomarker-defined disease subsets and combination activity with cisplatin or olaparib. Cancer Research. PMID 28490518 DOI: 10.1158/0008-5472.Can-16-3409 |
0.359 |
|
| 2017 |
Sen T, Chen L, Rodriguez BL, Yang Y, Fan YH, Stewart CA, Glisson B, Piwnica-Worms H, Sage J, Heymach JV, Gibbons DL, Byers LA. Abstract B72: Combining immune checkpoint inhibition and DNA damage repair (DDR) targeted therapy in small cell lung cancer (SCLC) Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-B72 |
0.323 |
|
| 2017 |
Powell E, Shao J, Picon H, Ge Z, Echeverria G, Peoples M, Bristow C, Cai S, Tu Y, McCoy A, Piwnica-Worms D, Draetta G, Edwards J, Moulder S, Symmans W, ... ... Piwnica-Worms H, et al. Abstract P6-01-08: Identifying metastatic drivers in patient derived xenograft models of triple negative breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs16-P6-01-08 |
0.308 |
|
| 2017 |
Redwood A, Cai S, Jeter-Jones S, Tu Y, Piwnica-Worms H. Abstract P5-06-06: Comprehensive analysis of the DNA damage repair and maintenance pathways that regulate TNBC sensitivity to replication stress Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P5-06-06 |
0.342 |
|
| 2017 |
Moulder S, Hess K, Rauch M, Astrada B, Litton J, Mittendorf E, Ueno N, Tripathy D, Lim B, Piwnica-Worms H, Thompson A, Symmans W. Abstract OT2-01-22: NCT02456857: A phase II trial of liposomal doxorubicin, bevacizumab and everolimus (DAE) in patients (pts) with localized triple-negative breast cancer (TNBC) with tumors predicted insensitive to standard neoadjuvant chemotherapy (NACT) Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Ot2-01-22 |
0.307 |
|
| 2016 |
Werden SJ, Sphyris N, Sarkar TR, Paranjape AN, LaBaff AM, Taube JH, Hollier BG, Ramirez-Peña EQ, Soundararajan R, den Hollander P, Powell E, Echeverria GV, Miura N, Chang JT, Piwnica-Worms H, et al. Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth. Oncogene. PMID 27292262 DOI: 10.1038/Onc.2016.203 |
0.405 |
|
| 2016 |
Powell E, Shao J, Yuan Y, Chen HC, Cai S, Echeverria GV, Mistry N, Decker KF, Schlosberg C, Do KA, Edwards JR, Liang H, Piwnica-Worms D, Piwnica-Worms H. p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer. Breast Cancer Research : Bcr. 18: 13. PMID 26818199 DOI: 10.1186/S13058-016-0673-9 |
0.331 |
|
| 2016 |
Redwood A, Cai S, Piwnica-Worms H. Abstract P4-07-02: Targeted therapies for TNBC: Exploiting vulnerabilities that arise from DNA damage repair pathway dependencies Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P4-07-02 |
0.427 |
|
| 2016 |
Echeverria G, Seth S, Moulder S, Symmans W, Chang J, Cai S, Heffernan T, Piwnica-Worms H. Abstract P3-06-04: Investigating clonal dynamics in triple negative breast cancer chemoresistance Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-06-04 |
0.343 |
|
| 2016 |
Echeverria GV, Seth S, Cai S, Moulder S, Symmans WF, Heffernan TP, Chang J, Piwnica-Worms H. Abstract 2406: Identifying and targeting chemoresistant subclones in triple negative breast cancer Cancer Research. 76: 2406-2406. DOI: 10.1158/1538-7445.Am2016-2406 |
0.334 |
|
| 2015 |
Tinkum KL, Stemler KM, White LS, Loza AJ, Jeter-Jones S, Michalski BM, Kuzmicki C, Pless R, Stappenbeck TS, Piwnica-Worms D, Piwnica-Worms H. Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival. Proceedings of the National Academy of Sciences of the United States of America. PMID 26644583 DOI: 10.1073/Pnas.1509249112 |
0.305 |
|
| 2015 |
Cheruiyot A, Paudyal SC, Kim IK, Sparks M, Ellenberger T, Piwnica-Worms H, You Z. Poly(ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities. Dna Repair. 35: 106-115. PMID 26519824 DOI: 10.1016/J.Dnarep.2015.09.021 |
0.392 |
|
| 2015 |
Teasley DC, Parajuli S, Nguyen M, Moore HR, Alspach E, Lock YJ, Honaker Y, Saharia A, Piwnica-Worms H, Stewart SA. Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand. The Journal of Biological Chemistry. 290: 15133-45. PMID 25922071 DOI: 10.1074/Jbc.M115.647388 |
0.764 |
|
| 2015 |
Chen X, Kim IK, Honaker Y, Paudyal SC, Koh WK, Sparks M, Li S, Piwnica-Worms H, Ellenberger T, You Z. 14-3-3 proteins restrain the Exo1 nuclease to prevent overresection. The Journal of Biological Chemistry. 290: 12300-12. PMID 25833945 DOI: 10.1074/Jbc.M115.644005 |
0.774 |
|
| 2015 |
Diamond MI, Cai S, Boudreau A, Carey CJ, Lyle N, Pappu RV, Swamidass SJ, Bissell M, Piwnica-Worms H, Shao J. Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1. The Journal of Biological Chemistry. 290: 9075-86. PMID 25681442 DOI: 10.1074/Jbc.M114.619874 |
0.417 |
|
| 2015 |
Valliani AA, Sen T, Masrorpour F, Diao L, Cardnell RJ, Wang J, Glisson BS, Piwnica-Worms H, Gibbons DL, Byers LA. Abstract 5316: Check point kinase 1 (Chk1) targeting as a novel therapeutic strategy in small cell lung cancer (SCLC) Cancer Research. 75: 5316-5316. DOI: 10.1158/1538-7445.Am2015-5316 |
0.407 |
|
| 2015 |
Tinkum KL, Stemler KM, White LS, Loza AJ, Jeter-Jones S, Michalski BM, Kuzmicki CE, Pless R, Stappenbeck T, Piwnica-Worms D, Piwnica-Worms H. Abstract 2316: Fasting protects mice from lethal DNA damage by promoting small intestinal stem cell survival and by inhibiting acute inflammation Cancer Research. 75: 2316-2316. DOI: 10.1158/1538-7445.Am2015-2316 |
0.335 |
|
| 2014 |
Powell E, Piwnica-Worms D, Piwnica-Worms H. Contribution of p53 to metastasis. Cancer Discovery. 4: 405-14. PMID 24658082 DOI: 10.1158/2159-8290.Cd-13-0136 |
0.354 |
|
| 2014 |
Lewandowski KT, Piwnica-Worms H. Phosphorylation of the E3 ubiquitin ligase RNF41 by the kinase Par-1b is required for epithelial cell polarity. Journal of Cell Science. 127: 315-27. PMID 24259665 DOI: 10.1242/Jcs.129148 |
0.414 |
|
| 2013 |
Ma CX, Ellis MJ, Petroni GR, Guo Z, Cai SR, Ryan CE, Craig Lockhart A, Naughton MJ, Pluard TJ, Brenin CM, Picus J, Creekmore AN, Mwandoro T, Yarde ER, Reed J, ... ... Piwnica-Worms H, et al. A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer. Breast Cancer Research and Treatment. 137: 483-92. PMID 23242585 DOI: 10.1007/S10549-012-2378-9 |
0.374 |
|
| 2013 |
Huh J, Piwnica-Worms H. CRL4(CDT2) targets CHK1 for PCNA-independent destruction. Molecular and Cellular Biology. 33: 213-26. PMID 23109433 DOI: 10.1128/Mcb.00847-12 |
0.661 |
|
| 2013 |
Origanti S, Cai SR, Munir AZ, White LS, Piwnica-Worms H. Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells Oncogene. 32: 577-588. PMID 22430210 DOI: 10.1038/Onc.2012.84 |
0.372 |
|
| 2012 |
Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, Ng S, Lin L, Crowder R, Snider J, Ballman K, ... ... Piwnica-Worms H, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 486: 353-60. PMID 22722193 DOI: 10.1038/Nature11143 |
0.326 |
|
| 2012 |
Duxin JP, Moore HR, Sidorova J, Karanja K, Honaker Y, Dao B, Piwnica-Worms H, Campbell JL, Monnat RJ, Stewart SA. Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication. The Journal of Biological Chemistry. 287: 21980-91. PMID 22570476 DOI: 10.1074/Jbc.M112.359018 |
0.788 |
|
| 2012 |
Ma CX, Cai S, Li S, Ryan CE, Guo Z, Schaiff WT, Lin L, Hoog J, Goiffon RJ, Prat A, Aft RL, Ellis MJ, Piwnica-Worms H. Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. The Journal of Clinical Investigation. 122: 1541-52. PMID 22446188 DOI: 10.1172/Jci58765 |
0.384 |
|
| 2012 |
Ma CX, Ellis MJ, Petroni GR, Lockhart AC, Naughton M, Pluard TJ, Brenin C, Picus J, Creekmore AN, Mwandoro TN, Guo Z, Cai S, Ryan C, Yarde E, Hoog J, ... ... Piwnica-Worms H, et al. Clinical and correlative science results in a phase II study of UCN-01in combination with irinotecan in recurrent triple-negative breast cancer (TNBC). Journal of Clinical Oncology. 30: 3047-3047. DOI: 10.1200/Jco.2012.30.15_Suppl.3047 |
0.334 |
|
| 2012 |
Ma CX, Cai S, Li S, Ryan CE, Guo Z, Schaiff WT, Lin L, Hoog J, Goiffon RJ, Prat A, Aft RL, Ellis MJ, Piwnica-Worms H. Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models (Journal of Clinical Investigation (2012) 122, 4 (1541-1552) DOI: 10.1172/JCI58765) Journal of Clinical Investigation. 122: 2702. DOI: 10.1172/Jci64256 |
0.312 |
|
| 2012 |
Powell E, Decker K, Cai S, Aft R, Edwards J, Piwnica-Worms D, Piwnica-Worms H. Abstract LB-114: Using molecular imaging to identify modulators of breast cancer metastasis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-114 |
0.339 |
|
| 2011 |
Tinkum KL, Marpegan L, White LS, Sun J, Herzog ED, Piwnica-Worms D, Piwnica-Worms H. Bioluminescence imaging captures the expression and dynamics of endogenous p21 promoter activity in living mice and intact cells. Molecular and Cellular Biology. 31: 3759-72. PMID 21791610 DOI: 10.1128/Mcb.05243-11 |
0.342 |
|
| 2011 |
Wang YV, Leblanc M, Fox N, Mao JH, Tinkum KL, Krummel K, Engle D, Piwnica-Worms D, Piwnica-Worms H, Balmain A, Kaushansky K, Wahl GM. Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes & Development. 25: 1426-38. PMID 21724834 DOI: 10.1101/Gad.2024411 |
0.382 |
|
| 2011 |
Lee G, Origanti S, White LS, Sun J, Stappenbeck TS, Piwnica-Worms H. Contributions made by CDC25 phosphatases to proliferation of intestinal epithelial stem and progenitor cells. Plos One. 6: e15561. PMID 21283624 DOI: 10.1371/Journal.Pone.0015561 |
0.705 |
|
| 2011 |
Ma CX, Janetka JW, Piwnica-Worms H. Death by releasing the breaks: CHK1 inhibitors as cancer therapeutics Trends in Molecular Medicine. 17: 88-96. PMID 21087899 DOI: 10.1016/J.Molmed.2010.10.009 |
0.435 |
|
| 2011 |
Fracasso PM, Williams KJ, Chen RC, Picus J, Ma CX, Ellis MJ, Tan BR, Pluard TJ, Adkins DR, Naughton MJ, Rader JS, Arquette MA, Fleshman JW, Creekmore AN, Goodner SA, ... ... Piwnica-Worms H, et al. A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies. Cancer Chemotherapy and Pharmacology. 67: 1225-37. PMID 20694727 DOI: 10.1007/S00280-010-1410-1 |
0.329 |
|
| 2010 |
Lennerz JK, Hurov JB, White LS, Lewandowski KT, Prior JL, Planer GJ, Gereau RW, Piwnica-Worms D, Schmidt RE, Piwnica-Worms H. Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis. Molecular and Cellular Biology. 30: 5043-56. PMID 20733003 DOI: 10.1128/Mcb.01472-09 |
0.74 |
|
| 2010 |
Honaker Y, Piwnica-Worms H. Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction Oncogene. 29: 3324-3334. PMID 20348946 DOI: 10.1038/Onc.2010.96 |
0.79 |
|
| 2010 |
Qian Z, Leung-Pineda V, Xuan B, Piwnica-Worms H, Yu D. Human cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis. Plos Pathogens. 6: e1000814. PMID 20333247 DOI: 10.1371/Journal.Ppat.1000814 |
0.364 |
|
| 2009 |
Granot Z, Swisa A, Magenheim J, Stolovich-Rain M, Fujimoto W, Manduchi E, Miki T, Lennerz JK, Stoeckert CJ, Meyuhas O, Seino S, Permutt MA, Piwnica-Worms H, Bardeesy N, Dor Y. LKB1 regulates pancreatic beta cell size, polarity, and function. Cell Metabolism. 10: 296-308. PMID 19808022 DOI: 10.1016/J.Cmet.2009.08.010 |
0.319 |
|
| 2009 |
Lin J, Hou KK, Piwnica-Worms H, Shaw AS. The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarization. Journal of Immunology (Baltimore, Md. : 1950). 183: 1215-21. PMID 19553522 DOI: 10.4049/Jimmunol.0803887 |
0.369 |
|
| 2009 |
Leung-Pineda V, Huh J, Piwnica-Worms H. DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress. Cancer Research. 69: 2630-7. PMID 19276361 DOI: 10.1158/0008-5472.Can-08-3382 |
0.69 |
|
| 2009 |
Lee G, White LS, Hurov KE, Stappenbeck TS, Piwnica-Worms H. Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion. Proceedings of the National Academy of Sciences of the United States of America. 106: 4701-6. PMID 19273838 DOI: 10.1073/Pnas.0900751106 |
0.704 |
|
| 2009 |
Ma C, Li S, Guo Z, Chris R, Hoog J, Lin L, Ellis M, Piwnica-Worms H. Targeted therapies for triple negative breast cancer based on TP53 status. Cancer Research. 69: 403. DOI: 10.1158/0008-5472.Sabcs-403 |
0.413 |
|
| 2008 |
Watkins JL, Lewandowski KT, Meek SE, Storz P, Toker A, Piwnica-Worms H. Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association. Proceedings of the National Academy of Sciences of the United States of America. 105: 18378-83. PMID 19011111 DOI: 10.1073/Pnas.0809661105 |
0.45 |
|
| 2008 |
Lovly CM, Yan L, Ryan CE, Takada S, Piwnica-Worms H. Regulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379. Molecular and Cellular Biology. 28: 5874-85. PMID 18644861 DOI: 10.1128/Mcb.00821-08 |
0.668 |
|
| 2008 |
Nakajima H, Yonemura S, Murata M, Nakamura N, Piwnica-Worms H, Nishida E. Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit. The Journal of Cell Biology. 181: 89-103. PMID 18378775 DOI: 10.1083/Jcb.200708176 |
0.415 |
|
| 2008 |
Kang T, Wei Y, Honaker Y, Yamaguchi H, Appella E, Hung MC, Piwnica-Worms H. GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers. Cancer Cell. 13: 36-47. PMID 18167338 DOI: 10.1016/J.Ccr.2007.12.002 |
0.772 |
|
| 2007 |
Tarakanova VL, Leung-Pineda V, Hwang S, Yang CW, Matatall K, Basson M, Sun R, Piwnica-Worms H, Sleckman BP, Virgin HW. Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. Cell Host & Microbe. 1: 275-86. PMID 18005708 DOI: 10.1016/J.Chom.2007.05.008 |
0.437 |
|
| 2007 |
King JB, Gross J, Lovly CM, Piwnica-Worms H, Townsend RR. Identification of protein phosphorylation sites within Ser/Thr-rich cluster domains using site-directed mutagenesis and hybrid linear quadrupole ion trap Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 21: 3443-51. PMID 17918214 DOI: 10.1002/Rcm.3223 |
0.576 |
|
| 2007 |
Hurov J, Piwnica-Worms H. The Par-1/MARK family of protein kinases: from polarity to metabolism. Cell Cycle (Georgetown, Tex.). 6: 1966-9. PMID 17721078 DOI: 10.4161/Cc.6.16.4576 |
0.77 |
|
| 2007 |
Hurov JB, Huang M, White LS, Lennerz J, Choi CS, Cho YR, Kim HJ, Prior JL, Piwnica-Worms D, Cantley LC, Kim JK, Shulman GI, Piwnica-Worms H. Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 5680-5. PMID 17372192 DOI: 10.1073/Pnas.0701179104 |
0.736 |
|
| 2006 |
Leung-Pineda V, Ryan CE, Piwnica-Worms H. Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit. Molecular and Cellular Biology. 26: 7529-38. PMID 17015476 DOI: 10.1128/Mcb.00447-06 |
0.467 |
|
| 2006 |
Chen YM, Wang QJ, Hu HS, Yu PC, Zhu J, Drewes G, Piwnica-Worms H, Luo ZG. Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity. Proceedings of the National Academy of Sciences of the United States of America. 103: 8534-9. PMID 16717194 DOI: 10.1073/Pnas.0509955103 |
0.326 |
|
| 2006 |
King JB, Gross J, Lovly CM, Rohrs H, Piwnica-Worms H, Townsend RR. Accurate mass-driven analysis for the characterization of protein phosphorylation. Study of the human Chk2 protein kinase. Analytical Chemistry. 78: 2171-81. PMID 16579595 DOI: 10.1021/Ac051520L |
0.564 |
|
| 2005 |
Ferguson AM, White LS, Donovan PJ, Piwnica-Worms H. Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. Molecular and Cellular Biology. 25: 2853-60. PMID 15767688 DOI: 10.1128/Mcb.25.7.2853-2860.2005 |
0.447 |
|
| 2005 |
Puc J, Keniry M, Li HS, Pandita TK, Choudhury AD, Memeo L, Mansukhani M, Murty VV, Gaciong Z, Meek SE, Piwnica-Worms H, Hibshoosh H, Parsons R. Lack of PTEN sequesters CHK1 and initiates genetic instability. Cancer Cell. 7: 193-204. PMID 15710331 DOI: 10.1016/J.Ccr.2005.01.009 |
0.456 |
|
| 2004 |
Murphy CI, Piwnica-Worms H, Grünwald S, Romanow WG, Francis N, Fan HY. Maintenance of insect cell cultures and generation of recombinant baculoviruses. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 16.10. PMID 18265340 DOI: 10.1002/0471142727.Mb1610S65 |
0.302 |
|
| 2004 |
Luker KE, Smith MC, Luker GD, Gammon ST, Piwnica-Worms H, Piwnica-Worms D. Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals. Proceedings of the National Academy of Sciences of the United States of America. 101: 12288-93. PMID 15284440 DOI: 10.1073/Pnas.0404041101 |
0.413 |
|
| 2004 |
Meek SE, Lane WS, Piwnica-Worms H. Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins. The Journal of Biological Chemistry. 279: 32046-54. PMID 15161933 DOI: 10.1074/Jbc.M403044200 |
0.376 |
|
| 2004 |
Hurov JB, Watkins JL, Piwnica-Worms H. Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity. Current Biology : Cb. 14: 736-41. PMID 15084291 DOI: 10.1016/J.Cub.2004.04.007 |
0.781 |
|
| 2003 |
Chen MS, Ryan CE, Piwnica-Worms H. Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding. Molecular and Cellular Biology. 23: 7488-97. PMID 14559997 DOI: 10.1128/Mcb.23.21.7488-7497.2003 |
0.473 |
|
| 2003 |
Schwarz JK, Lovly CM, Piwnica-Worms H. Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation. Molecular Cancer Research : McR. 1: 598-609. PMID 12805407 |
0.702 |
|
| 2003 |
Bulavin DV, Higashimoto Y, Demidenko ZN, Meek S, Graves P, Phillips C, Zhao H, Moody SA, Appella E, Piwnica-Worms H, Fornace AJ. Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nature Cell Biology. 5: 545-51. PMID 12766774 DOI: 10.1038/Ncb994 |
0.462 |
|
| 2002 |
Zhao H, Watkins JL, Piwnica-Worms H. Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proceedings of the National Academy of Sciences of the United States of America. 99: 14795-800. PMID 12399544 DOI: 10.1073/Pnas.182557299 |
0.504 |
|
| 2002 |
Luker GD, Sharma V, Pica CM, Dahlheimer JL, Li W, Ochesky J, Ryan CE, Piwnica-Worms H, Piwnica-Worms D. Noninvasive imaging of protein-protein interactions in living animals. Proceedings of the National Academy of Sciences of the United States of America. 99: 6961-6. PMID 11997447 DOI: 10.1073/Pnas.092022399 |
0.342 |
|
| 2002 |
Chen F, Zhang Z, Bower J, Lu Y, Leonard SS, Ding M, Castranova V, Piwnica-Worms H, Shi X. Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway. Proceedings of the National Academy of Sciences of the United States of America. 99: 1990-5. PMID 11842186 DOI: 10.1073/Pnas.032428899 |
0.398 |
|
| 2001 |
Rothblum-Oviatt CJ, Ryan CE, Piwnica-Worms H. 14-3-3 binding regulates catalytic activity of human Wee1 kinase. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 12: 581-9. PMID 11751453 |
0.337 |
|
| 2001 |
Müller J, Ory S, Copeland T, Piwnica-Worms H, Morrison DK. C-TAK1 Regulates Ras Signaling by Phosphorylating the MAPK Scaffold, KSR1 Molecular Cell. 8: 983-993. PMID 11741534 DOI: 10.1016/S1097-2765(01)00383-5 |
0.37 |
|
| 2001 |
Deming PB, Cistulli CA, Zhao H, Graves PR, Piwnica-Worms H, Paules RS, Downes CS, Kaufmann WK. The human decatenation checkpoint. Proceedings of the National Academy of Sciences of the United States of America. 98: 12044-9. PMID 11593014 DOI: 10.1073/Pnas.221430898 |
0.465 |
|
| 2001 |
Crawford DF, Piwnica-Worms H. The G2 DNA Damage Checkpoint Delays Expression of Genes Encoding Mitotic Regulators Journal of Biological Chemistry. 276: 37166-37177. PMID 11483598 DOI: 10.1074/Jbc.M103414200 |
0.372 |
|
| 2001 |
Zhao H, Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1 Molecular and Cellular Biology. 21: 4129-4139. PMID 11390642 DOI: 10.1128/Mcb.21.13.4129-4139.2001 |
0.486 |
|
| 2001 |
Chen MS, Hurov J, White LS, Woodford-Thomas T, Piwnica-Worms H. Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase Molecular and Cellular Biology. 21: 3853-3861. PMID 11359894 DOI: 10.1128/Mcb.21.12.3853-3861.2001 |
0.781 |
|
| 2001 |
Graves PR, Lovly CM, Uy GL, Piwnica-Worms H. Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding. Oncogene. 20: 1839-51. PMID 11313932 DOI: 10.1038/Sj.Onc.1204259 |
0.588 |
|
| 2001 |
Hurov JB, Stappenbeck TS, Zmasek CM, White LS, Ranganath SH, Russell JH, Chan AC, Murphy KM, Piwnica-Worms H. Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase. Molecular and Cellular Biology. 21: 3206-19. PMID 11287624 DOI: 10.1128/Mcb.21.9.3206-3219.2001 |
0.775 |
|
| 2000 |
Ahn JY, Schwarz JK, Piwnica-Worms H, Canman CE. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Research. 60: 5934-6. PMID 11085506 |
0.625 |
|
| 2000 |
Graves PR, Yu L, Schwarz JK, Gales J, Sausville EA, O'Connor PM, Piwnica-Worms H. The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. The Journal of Biological Chemistry. 275: 5600-5. PMID 10681541 DOI: 10.1074/Jbc.275.8.5600 |
0.677 |
|
| 1999 |
Piwnica-Worms H. Fools rush in Nature. 401: 535-537. PMID 10524615 DOI: 10.1038/44029 |
0.403 |
|
| 1999 |
Zeng Y, Piwnica-Worms H. DNA damage and replication checkpoints in fission yeast require nuclear exclusion of the Cdc25 phosphatase via 14-3-3 binding Molecular and Cellular Biology. 19: 7410-7419. PMID 10523629 DOI: 10.1128/Mcb.19.11.7410 |
0.41 |
|
| 1999 |
Liu F, Rothblum-Oviatt C, Ryan CE, Piwnica-Worms H. Overproduction of human Myt1 kinase induces a G2 cell cycle delay by interfering with the intracellular trafficking of Cdc2-cyclin B1 complexes. Molecular and Cellular Biology. 19: 5113-23. PMID 10373560 DOI: 10.1128/Mcb.19.7.5113 |
0.426 |
|
| 1999 |
Brown AL, Lee CH, Schwarz JK, Mitiku N, Piwnica-Worms H, Chung JH. A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 96: 3745-50. PMID 10097108 DOI: 10.1073/Pnas.96.7.3745 |
0.644 |
|
| 1998 |
Yu L, Orlandi L, Wang P, Orr MS, Senderowicz AM, Sausville EA, Silvestrini R, Watanabe N, Piwnica-Worms H, O'Connor PM. UCN-01 abrogates G2 arrest through a Cdc2-dependent pathway that is associated with inactivation of the Wee1Hu kinase and activation of the Cdc25C phosphatase Journal of Biological Chemistry. 273: 33455-33464. PMID 9837924 DOI: 10.1074/Jbc.273.50.33455 |
0.463 |
|
| 1998 |
Zeng Y, Forbes KC, Wu Z, Moreno S, Piwnica-Worms H, Enoch T. Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1. Nature. 395: 507-10. PMID 9774107 DOI: 10.1038/26766 |
0.496 |
|
| 1998 |
Thorson JA, Yu LW, Hsu AL, Shih NY, Graves PR, Tanner JW, Allen PM, Piwnica-Worms H, Shaw AS. 14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity. Molecular and Cellular Biology. 18: 5229-38. PMID 9710607 DOI: 10.1128/Mcb.18.9.5229 |
0.438 |
|
| 1998 |
Fauman EB, Cogswell JP, Lovejoy B, Rocque WJ, Holmes W, Montana VG, Piwnica-Worms H, Rink MJ, Saper MA. Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A. Cell. 93: 617-25. PMID 9604936 DOI: 10.1016/S0092-8674(00)81190-3 |
0.36 |
|
| 1998 |
Peng CY, Graves PR, Ogg S, Thoma RS, Byrnes MJ, Wu Z, Stephenson MT, Piwnica-Worms H. C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 9: 197-208. PMID 9543386 |
0.331 |
|
| 1998 |
Piwnica-Worms H. Mitonc- and g2 checkpoint-control Faseb Journal. 12. |
0.356 |
|
| 1997 |
Zhang SH, Kobayashi R, Graves PR, Piwnica-Worms H, Tonks NK. Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3β protein Journal of Biological Chemistry. 272: 27281-27287. PMID 9341175 DOI: 10.1074/Jbc.272.43.27281 |
0.344 |
|
| 1997 |
Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, Piwnica-Worms H. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science (New York, N.Y.). 277: 1501-5. PMID 9278512 DOI: 10.1126/Science.277.5331.1501 |
0.487 |
|
| 1997 |
Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ. Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25 Science. 277: 1497-1501. PMID 9278511 DOI: 10.1126/Science.277.5331.1497 |
0.498 |
|
| 1997 |
Liu F, Stanton JJ, Wu Z, Piwnica-Worms H. The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex Molecular and Cellular Biology. 17: 571-583. PMID 9001210 DOI: 10.1128/Mcb.17.2.571 |
0.436 |
|
| 1997 |
Peng CY, Gravesl PR, Thoma RS, Shaw AS, Piwnica-Worms H. Reversible phosphorylation and cell cycle control Faseb Journal. 11. |
0.356 |
|
| 1995 |
Parker LL, Sylvestre PJ, Byrnes MJ, Liu F, Piwnica-Worms H. Identification of a 95-kDa WEE1-like tyrosine kinase in HeLa cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9638-42. PMID 7568188 DOI: 10.1073/Pnas.92.21.9638 |
0.402 |
|
| 1994 |
Lee MS, Enoch T, Piwnica-Worms H. mik1+ encodes a tyrosine kinase that phosphorylates p34cdc2 on tyrosine 15. The Journal of Biological Chemistry. 269: 30530-7. PMID 7982971 |
0.31 |
|
| 1994 |
Ogg S, Gabrielli B, Piwnica-Worms H. Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216 Journal of Biological Chemistry. 269: 30461-30469. PMID 7982962 |
0.329 |
|
| 1994 |
Xu M, Sheppard KA, Peng CY, Yee AS, Piwnica-Worms H. Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Molecular and Cellular Biology. 14: 8420-31. PMID 7969176 DOI: 10.1128/mcb.14.12.8420-8431.1994 |
0.426 |
|
| 1994 |
Songyang Z, Blechner S, Hoagland N, Hoekstra MF, Piwnica-Worms H, Cantley LC. Use of an oriented peptide library to determine the optimal substrates of protein kinases Current Biology. 4: 973-982. PMID 7874496 DOI: 10.1016/S0960-9822(00)00221-9 |
0.414 |
|
| 1994 |
Atherton-Fessler S, Liu F, Gabrielli B, Lee MS, Peng CY, Piwnica-Worms H. Cell cycle regulation of the p34cdc2 inhibitory kinases. Molecular Biology of the Cell. 5: 989-1001. PMID 7841526 DOI: 10.1091/Mbc.5.9.989 |
0.459 |
|
| 1993 |
Parker LL, Walter SA, Young PG, Piwnica-Worms H. Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase. Nature. 363: 736-8. PMID 8515817 DOI: 10.1038/363736A0 |
0.446 |
|
| 1993 |
Atherton-Fessler S, Parker LL, Geahlen RL, Piwnica-Worms H. Mechanisms of p34cdc2 regulation. Molecular and Cellular Biology. 13: 1675-85. PMID 8441405 DOI: 10.1128/Mcb.13.3.1675 |
0.41 |
|
| 1993 |
Atherton-Fessler S, Hannig G, Piwnica-Worms H. Reversible tyrosine phosphorylation and cell cycle control Seminars in Cell and Developmental Biology. 4: 433-442. PMID 8305682 DOI: 10.1006/Scel.1993.1051 |
0.464 |
|
| 1993 |
Baumann K, Mandelkow EM, Biernat J, Piwnica-Worms H, Mandelkow E. Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5. Febs Letters. 336: 417-24. PMID 8282104 DOI: 10.1016/0014-5793(93)80849-P |
0.362 |
|
| 1992 |
Gabrielli BG, Lee MS, Walker DH, Piwnica-Worms H, Maller JL. Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex Journal of Biological Chemistry. 267: 18040-18046. PMID 1517236 |
0.362 |
|
| 1992 |
Parker LL, Piwnica-Worms H. Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science (New York, N.Y.). 257: 1955-7. PMID 1384126 DOI: 10.1126/Science.1384126 |
0.434 |
|
| 1992 |
Parker LL, Atherton-Fessler S, Piwnica-Worms H. p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15. Proceedings of the National Academy of Sciences of the United States of America. 89: 2917-21. PMID 1372994 DOI: 10.1073/Pnas.89.7.2917 |
0.427 |
|
| 1992 |
Auger KR, Carpenter CL, Shoelson SE, Piwnica-Worms H, Cantley LC. Polyoma virus middle T antigen-pp60c-src complex associates with purified phosphatidylinositol 3-kinase in vitro. The Journal of Biological Chemistry. 267: 5408-15. PMID 1372000 |
0.31 |
|
| 1992 |
Lee MS, Ogg S, Xu M, Parker LL, Donoghue DJ, Maller JL, Piwnica-Worms H. cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2. Molecular Biology of the Cell. 3: 73-84. PMID 1312880 DOI: 10.1091/Mbc.3.1.73 |
0.408 |
|
| 1991 |
Parker LL, Atherton-Fessler S, Lee MS, Ogg S, Falk JL, Swenson KI, Piwnica-Worms H. Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner. The Embo Journal. 10: 1255-63. PMID 1850698 DOI: 10.1002/J.1460-2075.1991.Tb08067.X |
0.437 |
|
| 1991 |
Piwnica-Worms H, Atherton-Fessler S, Lee MS, Ogg S, Swenson KI, Parker LL. p107wee1 is a serine/threonine and tyrosine kinase that promotes the tyrosine phosphorylation of the cyclin/p34cdc2 complex. Cold Spring Harbor Symposia On Quantitative Biology. 56: 567-76. PMID 1840265 DOI: 10.1101/Sqb.1991.056.01.064 |
0.391 |
|
| 1991 |
Roy LM, Swenson KI, Walker DH, Gabrielli BG, Li RS, Piwnica-Worms H, Maller JL. Activation of p34cdc2 kinase by cyclin A Journal of Cell Biology. 113: 507-514. PMID 1826688 DOI: 10.1083/Jcb.113.3.507 |
0.451 |
|
| 1991 |
Paris J, Swenson K, Piwnica-Worms H, Richter JD. Maturation-specific polyadenylation: In vitro activation by p34cdc2 and phosphorylation of a 58-kD CPE-binding protein Genes and Development. 5: 1697-1708. PMID 1653174 DOI: 10.1101/Gad.5.9.1697 |
0.394 |
|
| 1990 |
Furukawa Y, Piwnica-Worms H, Ernst TJ, Kanakura Y, Griffin JD. cdc2 gene expression at the G1 to S transition in human T lymphocytes Science. 250: 805-808. PMID 2237430 DOI: 10.1126/Science.2237430 |
0.35 |
|
| 1990 |
Piwnica-Worms H, Williams NG, Cheng SH, Roberts TM. Regulation of pp60c-src and its interaction with polyomavirus middle T antigen in insect cells Journal of Virology. 64: 61-68. PMID 2152834 DOI: 10.1128/Jvi.64.1.61-68.1990 |
0.457 |
|
| 1990 |
Swenson KI, Piwnica-Worms H, McNamee H, Paul DL. Tyrosine phosphorylation of the gap junction protein connexin43 is required for the pp60v-src-induced inhibition of communication Cell Regulation. 1: 989-1002. PMID 1966893 DOI: 10.1091/Mbc.1.13.989 |
0.356 |
|
| 1990 |
Cohen B, Yoakim M, Piwnica-Worms H, Roberts TM, Schaffhausen BS. Tyrosine phosphorylation is a signal for the trafficking of pp85, an 85-kDa phosphorylated polypeptide associated with phosphatidylinositol kinase activity Proceedings of the National Academy of Sciences of the United States of America. 87: 4458-4462. PMID 1693771 DOI: 10.1073/Pnas.87.12.4458 |
0.391 |
|
| 1989 |
DeCaprio JA, Ludlow JW, Lynch D, Furukawa Y, Griffin J, Piwnica-Worms H, Huang CM, Livingston DM. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element Cell. 58: 1085-1095. PMID 2673542 DOI: 10.1016/0092-8674(89)90507-2 |
0.387 |
|
| 1988 |
Murphy CI, Weiner B, Bikel I, Piwnica-Worms H, Bradley MK, Livingston DM. Purification and functional properties of simian virus 40 large and small T antigen overproduced in insect cells Journal of Virology. 62: 2951-2959. PMID 2969056 DOI: 10.1128/Jvi.62.8.2951-2959.1988 |
0.318 |
|
| 1988 |
Roberts TM, Kaplan D, Morgan W, Keller T, Mamon H, Piwnica-Worms H, Druker B, Cohen B, Schaffhausen B, Whitman M, Cantley L, Rapp U, Morrison D. Tyrosine phosphorylation in signal transduction Cold Spring Harbor Symposia On Quantitative Biology. 53: 161-171. PMID 2855480 DOI: 10.1101/Sqb.1988.053.01.022 |
0.336 |
|
| 1988 |
Draetta G, Piwnica-Worms H, Morrison D, Druker B, Roberts T, Beach D. Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate Nature. 336: 738-744. PMID 2462672 DOI: 10.1038/336738A0 |
0.463 |
|
| 1988 |
Cheng SH, Piwnica-Worms H, Harvey RW, Roberts TM, Smith AE. The carboxy terminus of pp60(c-src) is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus Molecular and Cellular Biology. 8: 1736-1747. PMID 2454396 DOI: 10.1128/Mcb.8.4.1736 |
0.406 |
|
| 1987 |
Piwnica-Worms H, Saunders KB, Roberts TM, Smith AE, Cheng SH. Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src Cell. 49: 75-82. PMID 3103926 DOI: 10.1016/0092-8674(87)90757-4 |
0.414 |
|
| 1986 |
Piwnica-Worms H, Kaplan DR, Whitman M, Roberts TM. Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivo Molecular and Cellular Biology. 6: 2033-2040. PMID 2431288 DOI: 10.1128/Mcb.6.6.2033 |
0.402 |
|
| 1986 |
Gee CE, Griffin J, Sastre L, Miller LJ, Springer TA, Piwnica-Worms H, Roberts TM. Differentiation of myeloid cells is accompanied by increased levels of pp60c-src protein and kinase activity. Proceedings of the National Academy of Sciences of the United States of America. 83: 5131-5. PMID 2425362 DOI: 10.1073/Pnas.83.14.5131 |
0.423 |
|
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