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Irwin J. Kopin - Publications

Affiliations: 
National Institute of Neurological Disorders and Stroke, Bethesda, MD, United States 
Area:
Dopamine, Parkinson's Disease
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351 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Goldstein DS, Holmes C, Sullivan P, Jinsmaa Y, Kopin IJ, Sharabi Y. Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies. Parkinsonism & Related Disorders. PMID 27474472 DOI: 10.1016/J.Parkreldis.2016.07.009  0.309
2016 Goldstein DS, Jinsmaa Y, Sullivan P, Holmes C, Kopin IJ, Sharabi Y. 3,4-Dihydroxyphenylethanol (Hydroxytyrosol) Mitigates the Increase in Spontaneous Oxidation of Dopamine During Monoamine Oxidase Inhibition in PC12 Cells. Neurochemical Research. PMID 27220335 DOI: 10.1007/S11064-016-1959-0  0.322
2015 Goldstein DS, Jinsmaa Y, Sullivan P, Holmes C, Kopin IJ, Sharabi Y. Comparison of monoamine oxidase inhibitors in decreasing production of the autotoxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL) in PC12 cells. The Journal of Pharmacology and Experimental Therapeutics. PMID 26574516 DOI: 10.1124/Jpet.115.230201  0.343
2015 Goldstein DS, Holmes C, Sullivan P, Mash DC, Sidransky E, Stefani A, Kopin IJ, Sharabi Y. Deficient vesicular storage: A common theme in catecholaminergic neurodegeneration. Parkinsonism & Related Disorders. 21: 1013-22. PMID 26255205 DOI: 10.1016/J.Parkreldis.2015.07.009  0.314
2015 Goldstein DS, Sullivan P, Cooney A, Jinsmaa Y, Kopin IJ, Sharabi Y. Rotenone decreases intracellular aldehyde dehydrogenase activity: implications for the pathogenesis of Parkinson's disease. Journal of Neurochemistry. 133: 14-25. PMID 25645689 DOI: 10.1111/Jnc.13042  0.348
2012 Goldstein DS, Sullivan P, Cooney A, Jinsmaa Y, Sullivan R, Gross DJ, Holmes C, Kopin IJ, Sharabi Y. Vesicular uptake blockade generates the toxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde in PC12 cells: relevance to the pathogenesis of Parkinson's disease. Journal of Neurochemistry. 123: 932-43. PMID 22906103 DOI: 10.1111/J.1471-4159.2012.07924.X  0.331
2009 Eisenhofer G, Goldstein D, Kopin I. Simultaneous liquid-chromatographic determination of plasma catecholamines and metabolites Clinical Chemistry. 55: 2223-2224. PMID 19833834 DOI: 10.1373/Clinchem.2009.134478  0.33
2004 Eisenhofer G, Kopin IJ, Goldstein DS. Catecholamine metabolism: a contemporary view with implications for physiology and medicine. Pharmacological Reviews. 56: 331-49. PMID 15317907 DOI: 10.1124/Pr.56.3.1  0.327
2004 Eisenhofer G, Kopin IJ, Goldstein DS. Leaky catecholamine stores: undue waste or a stress response coping mechanism? Annals of the New York Academy of Sciences. 1018: 224-30. PMID 15240373 DOI: 10.1196/Annals.1296.027  0.362
2004 Eldadah BA, Pacak K, Eisenhofer G, Holmes C, Kopin IJ, Goldstein DS. Cardiac uptake-1 inhibition by high circulating norepinephrine levels in patients with pheochromocytoma. Hypertension. 43: 1227-32. PMID 15078865 DOI: 10.1161/01.Hyp.0000127305.87552.D6  0.344
2004 Eldadah BA, Pacak K, Eisenhofer G, Holmes C, Kopin IJ, Goldstein DS. Inhibition of uptake-1 activity in the human heart in a hypernoradrenergic state Clinical Pharmacology & Therapeutics. 75: 54. DOI: 10.1016/J.Clpt.2003.11.206  0.333
2003 Eisenhofer G, Goldstein DS, Kopin IJ, Crout JR. Pheochromocytoma: rediscovery as a catecholamine-metabolizing tumor. Endocrine Pathology. 14: 193-212. PMID 14586065 DOI: 10.1007/S12022-003-0012-4  0.33
2003 Goldstein DS, Eisenhofer G, Kopin IJ. Sources and significance of plasma levels of catechols and their metabolites in humans. The Journal of Pharmacology and Experimental Therapeutics. 305: 800-11. PMID 12649306 DOI: 10.1124/Jpet.103.049270  0.363
2002 Kawamura M, Eisenhofer G, Kopin IJ, Kador PF, Lee YS, Fujisawa S, Sato S. Aldose reductase: an aldehyde scavenging enzyme in the intraneuronal metabolism of norepinephrine in human sympathetic ganglia. Autonomic Neuroscience : Basic & Clinical. 96: 131-9. PMID 11958479 DOI: 10.1016/S1566-0702(01)00385-X  0.314
2000 Yadid G, Harvey-White JD, Kopin IJ, Goldstein DS. Estimation of striatal dopamine spillover and metabolism in vivo. Neuroreport. 11: 3367-73. PMID 11059904 DOI: 10.1097/00001756-200010200-00021  0.383
2000 Lamensdorf I, Hrycyna C, He LP, Nechushtan A, Tjurmina O, Harvey-White J, Eisenhofer G, Rojas E, Kopin IJ. Acidic dopamine metabolites are actively extruded from PC12 cells by a novel sulfonylurea-sensitive transporter. Naunyn-Schmiedeberg's Archives of Pharmacology. 361: 654-64. PMID 10882041 DOI: 10.1007/S002100000246  0.311
2000 Lamensdorf I, Eisenhofer G, Harvey-White J, Nechustan A, Kirk K, Kopin IJ. 3,4-Dihydroxyphenylacetaldehyde potentiates the toxic effects of metabolic stress in PC12 cells. Brain Research. 868: 191-201. PMID 10854571 DOI: 10.1016/S0006-8993(00)02309-X  0.304
2000 Lamensdorf I, Eisenhofer G, Harvey-White J, Hayakawa Y, Kirk K, Kopin IJ. Metabolic stress in PC12 cells induces the formation of the endogenous dopaminergic neurotoxin, 3,4-dihydroxyphenylacetaldehyde. Journal of Neuroscience Research. 60: 552-8. PMID 10797558 DOI: 10.1002/(Sici)1097-4547(20000515)60:4<552::Aid-Jnr14>3.0.Co;2-U  0.304
2000 Lamensdorf I, He L, Nechushtan A, Harvey-White J, Eisenhofer G, Milan R, Rojas E, Kopin IJ. Effect of glipizide on dopamine synthesis, release and metabolism in PC12 cells. European Journal of Pharmacology. 388: 147-54. PMID 10666506 DOI: 10.1016/S0014-2999(99)00839-0  0.326
1999 Kawamura M, Eisenhofer G, Kopin IJ, Kador PF, Lee YS, Tsai JY, Fujisawa S, Lizak MJ, Sinz A, Sato S. Aldose reductase, a key enzyme in the oxidative deamination of norepinephrine in rats. Biochemical Pharmacology. 58: 517-24. PMID 10424772 DOI: 10.1016/S0006-2952(99)00121-5  0.377
1999 Sato S, Kawamura M, Eisenhofer G, Kopin IJ, Fujisawa S, Kador PF. Aldo-keto reductases in norepinephrine metabolism. Advances in Experimental Medicine and Biology. 463: 459-63. PMID 10352719 DOI: 10.1007/978-1-4615-4735-8_57  0.311
1999 Tjurmina OA, Goldstein DS, Palkovits M, Kopin IJ. Alpha2-adrenoceptor-mediated restraint of norepinephrine synthesis, release, and turnover during immobilization in rats. Brain Research. 826: 243-52. PMID 10224302 DOI: 10.1016/S0006-8993(99)01281-0  0.392
1999 Lamensdorf I, Meiri N, Harvey-White J, Jacobowitz DM, Kopin IJ. Kir6.2 oligoantisense administered into the globus pallidus reduces apomorphine-induced turning in 6-OHDA hemiparkinsonian rats. Brain Research. 818: 275-84. PMID 10082813 DOI: 10.1016/S0006-8993(98)01290-6  0.328
1999 Kawamura M, Schwartz JP, Nomura T, Kopin IJ, Goldstein DS, Huynh TT, Hooper DR, Harvey-White J, Eisenhofer G. Differential effects of chemical sympathectomy on expression and activity of tyrosine hydroxylase and levels of catecholamines and DOPA in peripheral tissues of rats. Neurochemical Research. 24: 25-32. PMID 9973233 DOI: 10.1023/A:1020919828028  0.319
1998 Kopin IJ, Rundqvist B, Friberg P, Lenders J, Goldstein DS, Eisenhofer G. Different relationships of spillover to release of norepinephrine in human heart, kidneys, and forearm. The American Journal of Physiology. 275: R165-73. PMID 9688975 DOI: 10.1152/Ajpregu.1998.275.1.R165  0.337
1998 Axelrod FB, Goldstein DS, Holmes C, Kopin IJ. Genotype and phenotype in familial dysautonomia. Advances in Pharmacology (San Diego, Calif.). 42: 925-8. PMID 9328049 DOI: 10.1016/S1054-3589(08)60898-4  0.363
1998 Kvetnanský R, Pacák K, Sabban EL, Kopin IJ, Goldstein DS. Stressor specificity of peripheral catecholaminergic activation. Advances in Pharmacology (San Diego, Calif.). 42: 556-60. PMID 9327962 DOI: 10.1016/S1054-3589(08)60811-X  0.354
1997 Kawamura M, Kopin IJ, Kador PF, Sato S, Tjurmina O, Eisenhofer G. Effects of aldehyde/aldose reductase inhibition on neuronal metabolism of norepinephrine. Journal of the Autonomic Nervous System. 66: 145-8. PMID 9406118 DOI: 10.1016/S0165-1838(97)00086-6  0.376
1996 WURTMAN RJ, KOPIN IJ, HORST D, FISCHER JE. EPINEPHRINE AND ORGAN BLOOD FLOW: EFFECTS OF HYPERTHYROIDISM, COCAINE, AND DENERVATION. The American Journal of Physiology. 207: 1247-50. PMID 14251927 DOI: 10.1152/Ajplegacy.1964.207.6.1247  0.348
1996 Fukuhara K, Kvetnansky R, Weise VK, Ohara H, Yoneda R, Goldstein DS, Kopin IJ. Effects of continuous and intermittent cold (SART) stress on sympathoadrenal system activity in rats. Journal of Neuroendocrinology. 8: 65-72. PMID 8932738 DOI: 10.1111/J.1365-2826.1996.Tb00687.X  0.335
1996 Axelrod FB, Goldstein DS, Holmes C, Berlin D, Kopin IJ. Pattern of plasma levels of catecholamines in familial dysautonomia. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society. 6: 205-9. PMID 8902316 DOI: 10.1007/Bf02291135  0.358
1996 Yamamoto T, Polinsky RJ, Goldstein DS, Baucom CE, Kopin IJ. Plasma sulfoconjugated dopamine levels are normal in patients with autonomic failure. The Journal of Laboratory and Clinical Medicine. 128: 488-91. PMID 8900291 DOI: 10.1016/S0022-2143(96)90045-1  0.345
1996 Eisenhofer G, Lenders JW, Harvey-White J, Ernst M, Zametkin A, Murphy DL, Kopin IJ. Differential inhibition of neuronal and extraneuronal monoamine oxidase. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 296-301. PMID 8873113 DOI: 10.1016/0893-133X(95)00233-4  0.325
1996 Al-Damluji S, Kopin IJ. Binding and competitive inhibition of amine uptake at postsynaptic neurones (transport-P) by tricyclic antidepressants. British Journal of Pharmacology. 117: 811-6. PMID 8851495 DOI: 10.1111/J.1476-5381.1996.Tb15265.X  0.311
1996 Pacak K, Palkovits M, Makino S, Kopin IJ, Goldstein DS. Brainstem hemisection decreases corticotropin-releasing hormone mRNA in the paraventricular nucleus but not in the central amygdaloid nucleus. Journal of Neuroendocrinology. 8: 543-51. PMID 8843023 DOI: 10.1046/J.1365-2826.1996.04888.X  0.33
1996 Fukuhara K, Kvetnansky R, Cizza G, Pacak K, Ohara H, Goldstein DS, Kopin IJ. Interrelations between sympathoadrenal system and hypothalamo-pituitary-adrenocortical/thyroid systems in rats exposed to cold stress. Journal of Neuroendocrinology. 8: 533-41. PMID 8843022 DOI: 10.1046/J.1365-2826.1996.04877.X  0.41
1996 Al-Damluji S, Kopin IJ. Functional properties of the uptake of amines in immortalised peptidergic neurones (transport-P). British Journal of Pharmacology. 117: 111-8. PMID 8825351 DOI: 10.1111/J.1476-5381.1996.Tb15162.X  0.307
1996 Eisenhofer G, Friberg P, Rundqvist B, Quyyumi AA, Lambert G, Kaye DM, Kopin IJ, Goldstein DS, Esler MD. Cardiac sympathetic nerve function in congestive heart failure. Circulation. 93: 1667-76. PMID 8653872 DOI: 10.1161/01.Cir.93.9.1667  0.314
1996 Kvetnanský R, Nankova B, Hiremagalur B, Viskupic E, Vietor I, Rusnak M, McMahon A, Kopin IJ, Sabban EL. Induction of adrenal tyrosine hydroxylase mRNA by single immobilization stress occurs even after splanchnic transection and in the presence of cholinergic antagonists. Journal of Neurochemistry. 66: 138-46. PMID 8522945 DOI: 10.1046/J.1471-4159.1996.66010138.X  0.307
1995 Chang PC, Grossman E, Kopin IJ, Goldstein DS, Folio CJ, Holmes C. On the existence of functional angiotensin II receptors on vascular sympathetic nerve terminals in the human forearm. Journal of Hypertension. 13: 1275-84. PMID 8984125 DOI: 10.1097/00004872-199511000-00009  0.335
1995 Kvetnanský R, Pacák K, Fukuhara K, Viskupic E, Hiremagalur B, Nankova B, Goldstein DS, Sabban EL, Kopin IJ. Sympathoadrenal system in stress. Interaction with the hypothalamic-pituitary-adrenocortical system. Annals of the New York Academy of Sciences. 771: 131-58. PMID 8597393 DOI: 10.1111/J.1749-6632.1995.Tb44676.X  0.386
1995 Pacák K, Palkovits M, Kvetnanský R, Yadid G, Kopin IJ, Goldstein DS. Effects of various stressors on in vivo norepinephrine release in the hypothalamic paraventricular nucleus and on the pituitary-adrenocortical axis. Annals of the New York Academy of Sciences. 771: 115-30. PMID 8597392 DOI: 10.1111/J.1749-6632.1995.Tb44675.X  0.379
1995 Pacak K, McCarty R, Palkovits M, Kopin IJ, Goldstein DS. Effects of immobilization on in vivo release of norepinephrine in the bed nucleus of the stria terminalis in conscious rats. Brain Research. 688: 242-6. PMID 8542318 DOI: 10.1016/0006-8993(95)00566-9  0.643
1995 Cizza G, Pacak K, Kvetnansky R, Palkovits M, Goldstein DS, Brady LS, Fukuhara K, Bergamini E, Kopin IJ, Blackman MR. Decreased stress responsivity of central and peripheral catecholaminergic systems in aged 344/N Fischer rats. The Journal of Clinical Investigation. 95: 1217-24. PMID 7883970 DOI: 10.1172/Jci117771  0.406
1995 Yadid G, Goldstein DS, Pacak K, Kopin IJ, Golomb E. Functional alpha 3-glycine receptors in rat adrenal. European Journal of Pharmacology. 288: 399-401. PMID 7774687 DOI: 10.1016/0922-4106(95)90056-X  0.306
1995 Pacak K, McCarty R, Palkovits M, Cizza G, Kopin IJ, Goldstein DS, Chrousos GP. Decreased central and peripheral catecholaminergic activation in obese Zucker rats. Endocrinology. 136: 4360-7. PMID 7664655 DOI: 10.1210/Endo.136.10.7664655  0.605
1995 Finberg JP, Wang J, Goldstein DS, Kopin IJ, Bankiewicz KS. Influence of selective inhibition of monoamine oxidase A or B on striatal metabolism of L-DOPA in hemiparkinsonian rats. Journal of Neurochemistry. 65: 1213-20. PMID 7643100 DOI: 10.1046/J.1471-4159.1995.65031213.X  0.366
1995 Pacak K, Palkovits M, Kopin IJ, Goldstein DS. Stress-induced norepinephrine release in the hypothalamic paraventricular nucleus and pituitary-adrenocortical and sympathoadrenal activity: in vivo microdialysis studies. Frontiers in Neuroendocrinology. 16: 89-150. PMID 7621982 DOI: 10.1006/Frne.1995.1004  0.387
1995 Pacak K, Palkovits M, Kvetnansky R, Matern P, Hart C, Kopin IJ, Goldstein DS. Catecholaminergic inhibition by hypercortisolemia in the paraventricular nucleus of conscious rats. Endocrinology. 136: 4814-9. PMID 7588211 DOI: 10.1210/Endo.136.11.7588211  0.441
1995 Eisenhofer G, Rundquist B, Aneman A, Friberg P, Dakak N, Kopin IJ, Jacobs MC, Lenders JW. Regional release and removal of catecholamines and extraneuronal metabolism to metanephrines. The Journal of Clinical Endocrinology and Metabolism. 80: 3009-17. PMID 7559889 DOI: 10.1210/Jcem.80.10.7559889  0.324
1995 Wolfovitz E, Pacak K, Abassi Z, Kopin IJ, Goldstein DS. Effects of hypercortisolemia or hyperinsulinemia on neurochemical indices of catecholamine release and synthesis in conscious rats. Journal of the Autonomic Nervous System. 54: 104-12. PMID 7499722 DOI: 10.1016/0165-1838(94)00192-M  0.382
1995 Schildkraut JJ, Kopin IJ, Schanberg SM, Durell J. Norepinephrine metabolism and psychoactive drugs in the endogenous depressions. 1968. Pharmacopsychiatry. 28: 24-37. PMID 7480108 DOI: 10.1055/S-2007-979616  0.674
1994 Kvetnansky R, Noskov VB, Blazicek P, Macho L, Grigoriev AI, Goldstein DS, Kopin IJ. New approaches to evaluate sympathoadrenal system activity in experiments on earth and in space. Acta Astronautica. 34: 243-54. PMID 11540743 DOI: 10.1016/0094-5765(94)90261-5  0.354
1994 Viskupic E, Kvetnansky R, Sabban EL, Fukuhara K, Weise VK, Kopin IJ, Schwartz JP. Increase in rat adrenal phenylethanolamine N-methyltransferase mRNA level caused by immobilization stress depends on intact pituitary-adrenocortical axis. Journal of Neurochemistry. 63: 808-14. PMID 8051564 DOI: 10.1046/J.1471-4159.1994.63030808.X  0.321
1994 Chang PC, Grossman E, Kopin IJ, Goldstein DS. On the existence of functional beta-adrenoceptors on vascular sympathetic nerve endings in the human forearm. Journal of Hypertension. 12: 681-90. PMID 7963493 DOI: 10.1097/00004872-199406000-00008  0.329
1994 Eisenhofer G, Pecorella W, Pacak K, Hooper D, Kopin IJ, Goldstein DS. The neuronal and extraneuronal origins of plasma 3-methoxy-4-hydroxyphenylglycol in rats. Journal of the Autonomic Nervous System. 50: 93-107. PMID 7844319 DOI: 10.1016/0165-1838(94)90127-9  0.38
1993 Wolfovitz E, Grossman E, Folio CJ, Keiser HR, Kopin IJ, Goldstein DS. Derivation of urinary dopamine from plasma dihydroxyphenylalanine in humans. Clinical Science (London, England : 1979). 84: 549-57. PMID 8504632 DOI: 10.1042/Cs0840549  0.366
1993 Pacák K, Yadid G, Jakab G, Lenders JW, Kopin IJ, Goldstein DS. In vivo hypothalamic release and synthesis of catecholamines in spontaneously hypertensive rats. Hypertension. 22: 467-78. PMID 8406651 DOI: 10.1161/01.Hyp.22.4.467  0.431
1993 Sheng JG, McShane LM, Plunkett RJ, Cummins AC, Oldfield EH, Kopin IJ, Palmatier MA. Dopaminergic neuronal sprouting and behavioral recovery in hemi-parkinsonian rats after implantation of amnion cells. Experimental Neurology. 123: 192-203. PMID 8405285 DOI: 10.1006/Exnr.1993.1152  0.326
1993 Kopin IJ. Parkinson's disease: past, present, and future. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 9: 1-12. PMID 8397719 DOI: 10.1038/Npp.1993.39  0.307
1993 Kvetnanský R, Fukuhara K, Pacák K, Cizza G, Goldstein DS, Kopin IJ. Endogenous glucocorticoids restrain catecholamine synthesis and release at rest and during immobilization stress in rats. Endocrinology. 133: 1411-9. PMID 8396019 DOI: 10.1210/Endo.133.3.8396019  0.44
1993 Pacák K, Kvetnanský R, Palkovits M, Fukuhara K, Yadid G, Kopin IJ, Goldstein DS. Adrenalectomy augments in vivo release of norepinephrine in the paraventricular nucleus during immobilization stress. Endocrinology. 133: 1404-10. PMID 8396018 DOI: 10.1210/Endo.133.3.8396018  0.42
1993 Finberg JP, Pacak K, Kopin IJ, Goldstein DS. Chronic inhibition of monoamine oxidase type A increases noradrenaline release in rat frontal cortex. Naunyn-Schmiedeberg's Archives of Pharmacology. 347: 500-5. PMID 8391652 DOI: 10.1007/Bf00166742  0.379
1993 Pacák K, Palkovits M, Kvetnanský R, Fukuhara K, Armando I, Kopin IJ, Goldstein DS. Effects of single or repeated immobilization on release of norepinephrine and its metabolites in the central nucleus of the amygdala in conscious rats. Neuroendocrinology. 57: 626-33. PMID 8367029 DOI: 10.1159/000126417  0.44
1993 Nankova B, Devlin D, Kvetnanský R, Kopin IJ, Sabban EL. Repeated immobilization stress increases the binding of c-Fos-like proteins to a rat dopamine beta-hydroxylase promoter enhancer sequence. Journal of Neurochemistry. 61: 776-9. PMID 8336155 DOI: 10.1111/J.1471-4159.1993.Tb02188.X  0.316
1993 Pacák K, Palkovits M, Kvetnansky R, Kopin IJ, Goldstein DS. Stress-induced norepinephrine release in the paraventricular nucleus of rats with brainstem hemisections: a microdialysis study. Neuroendocrinology. 58: 196-201. PMID 8264865 DOI: 10.1159/000126533  0.421
1993 Yadid G, Pacak K, Golomb E, Harvey-White JD, Lieberman DM, Kopin IJ, Goldstein DS. Glycine stimulates striatal dopamine release in conscious rats. British Journal of Pharmacology. 110: 50-3. PMID 8220914 DOI: 10.1111/J.1476-5381.1993.Tb13770.X  0.36
1993 Yadid G, Pacak K, Kopin IJ, Goldstein DS. Modified microdialysis probe for sampling extracellular fluid and administering drugs in vivo. The American Journal of Physiology. 265: R1205-11. PMID 7902019 DOI: 10.1152/Ajpregu.1993.265.5.R1205  0.319
1992 Kvetnanský R, Goldstein DS, Weise VK, Holmes C, Szemeredi K, Bagdy G, Kopin IJ. Effects of handling or immobilization on plasma levels of 3,4-dihydroxyphenylalanine, catecholamines, and metabolites in rats. Journal of Neurochemistry. 58: 2296-302. PMID 1573408 DOI: 10.1111/J.1471-4159.1992.Tb10977.X  0.417
1992 Pacak K, Armando I, Komoly S, Fukuhara K, Weise VK, Holmes C, Kopin IJ, Goldstein DS. Hypercortisolemia inhibits yohimbine-induced release of norepinephrine in the posterolateral hypothalamus of conscious rats. Endocrinology. 131: 1369-76. PMID 1505468 DOI: 10.1210/Endo.131.3.1505468  0.427
1992 Pacak K, Armando I, Fukuhara K, Kvetnansky R, Palkovits M, Kopin IJ, Goldstein DS. Noradrenergic activation in the paraventricular nucleus during acute and chronic immobilization stress in rats: an in vivo microdialysis study. Brain Research. 589: 91-6. PMID 1422825 DOI: 10.1016/0006-8993(92)91165-B  0.379
1992 McMahon A, Kvetnanský R, Fukuhara K, Weise VK, Kopin IJ, Sabban EL. Regulation of tyrosine hydroxylase and dopamine beta-hydroxylase mRNA levels in rat adrenals by a single and repeated immobilization stress. Journal of Neurochemistry. 58: 2124-30. PMID 1349344 DOI: 10.1111/J.1471-4159.1992.Tb10954.X  0.324
1992 Grossman E, Hoffman A, Armando I, Abassi Z, Kopin IJ, Goldstein DS. Sympathoadrenal contribution to plasma dopa (3,4-dihydroxyphenylalanine) in rats. Clinical Science (London, England : 1979). 83: 65-74. PMID 1325324 DOI: 10.1042/Cs0830065  0.382
1991 Szemeredi K, Komoly S, Kopin IJ, Bagdy G, Keiser HR, Goldstein DS. Simultaneous measurement of plasma and brain extracellular fluid concentrations of catechols after yohimbine administration in rats. Brain Research. 542: 8-14. PMID 2054662 DOI: 10.1016/0006-8993(91)90990-D  0.418
1991 Grossman E, Chang PC, Hoffman A, Tamrat M, Kopin IJ, Goldstein DS. Tracer norepinephrine kinetics: dependence on regional blood flow and the site of infusion. The American Journal of Physiology. 260: R946-52. PMID 2035707 DOI: 10.1152/Ajpregu.1991.260.5.R946  0.317
1991 Palombo E, Porrino LJ, Crane AM, Bankiewicz KS, Kopin IJ, Sokoloff L. Cerebral metabolic effects of monoamine oxidase inhibition in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine acutely treated monkeys. Journal of Neurochemistry. 56: 1639-46. PMID 2013759 DOI: 10.1111/J.1471-4159.1991.Tb02062.X  0.515
1991 Eisenhofer G, Esler MD, Goldstein DS, Kopin IJ. Neuronal uptake, metabolism, and release of tritium-labeled norepinephrine during assessment of its plasma kinetics. The American Journal of Physiology. 261: E505-15. PMID 1928342 DOI: 10.1152/Ajpendo.1991.261.4.E505  0.348
1991 Szemeredi K, Pacak K, Kopin IJ, Goldstein DS. Sympathoneural and skeletal muscle contributions to plasma dopa responses in pithed rats. Journal of the Autonomic Nervous System. 35: 169-74. PMID 1744376 DOI: 10.1016/0165-1838(91)90094-J  0.333
1991 Goldstein DS, Grossman E, Tamrat M, Chang PC, Eisenhofer G, Bacher J, Kirk KL, Bacharach S, Kopin IJ. Positron emission imaging of cardiac sympathetic innervation and function using 18F-6-fluorodopamine: effects of chemical sympathectomy by 6-hydroxydopamine. Journal of Hypertension. 9: 417-23. PMID 1649861 DOI: 10.1097/00004872-199105000-00005  0.308
1990 Palombo E, Porrino LJ, Bankiewicz KS, Crane AM, Sokoloff L, Kopin IJ. Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracarotid infusion of the neurotoxin MPTP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 860-9. PMID 2319306 DOI: 10.1523/Jneurosci.10-03-00860.1990  0.423
1990 Hovevey-Sion D, Eisenhofer G, Kopin IJ, Kirk KL, Chang PC, Szemeredi K, Goldstein DS. Metabolic fate of injected radiolabelled dopamine and 2-fluorodopamine in rats. Neuropharmacology. 29: 881-7. PMID 2255383 DOI: 10.1016/0028-3908(90)90137-G  0.387
1989 Eisenhofer G, Goldstein DS, Kopin IJ. Plasma dihydroxyphenylglycol for estimation of noradrenaline neuronal re-uptake in the sympathetic nervous system in vivo. Clinical Science (London, England : 1979). 76: 171-82. PMID 2924508 DOI: 10.1042/Cs0760171  0.363
1989 Deka-Starosta A, Garty M, Zukowska-Grojec Z, Keiser HR, Kopin IJ, Goldstein DS. Renal sympathetic nerve activity and norepinephrine release in rats. The American Journal of Physiology. 257: R229-36. PMID 2750962 DOI: 10.1152/Ajpregu.1989.257.1.R229  0.334
1989 Garty M, Deka-Starosta A, Stull R, Kopin IJ, Goldstein DS. Plasma levels of catechols after fasting in intact or adrenal-demedullated rats. Journal of the Autonomic Nervous System. 26: 181-4. PMID 2723338 DOI: 10.1016/0165-1838(89)90167-7  0.384
1989 Szemeredi K, Stull R, Kopin IJ, Goldstein DS. Effects of a peripherally acting alpha 2-adrenoceptor antagonist (L-659,066) on hemodynamics and plasma levels of catechols in conscious rats. European Journal of Pharmacology. 170: 53-9. PMID 2575527 DOI: 10.1016/0014-2999(89)90133-7  0.347
1989 Johannessen JN, Chiueh CC, Bacon JP, Garrick NA, Burns RS, Weise VK, Kopin IJ, Parisi JE, Markey SP. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the dog: effect of pargyline pretreatment. Journal of Neurochemistry. 53: 582-9. PMID 2568405 DOI: 10.1111/J.1471-4159.1989.Tb07373.X  0.339
1989 Szemeredi K, Zukowska-Grojec Z, Bagdy G, Fekete MI, Kopin IJ. Opposite effects of chronic cortisol treatment on pre- and postsynaptic actions of clonidine in pithed rats. Journal of Autonomic Pharmacology. 9: 35-43. PMID 2566614 DOI: 10.1111/J.1474-8673.1989.Tb00194.X  0.376
1989 Eisenhofer G, Brush JE, Cannon RO, Stull R, Kopin IJ, Goldstein DS. Plasma dihydroxyphenylalanine and total body and regional noradrenergic activity in humans. The Journal of Clinical Endocrinology and Metabolism. 68: 247-55. PMID 2563731 DOI: 10.1210/Jcem-68-2-247  0.333
1989 Goldstein DS, Polinsky RJ, Garty M, Robertson D, Brown RT, Biaggioni I, Stull R, Kopin IJ. Patterns of plasma levels of catechols in neurogenic orthostatic hypotension. Annals of Neurology. 26: 558-63. PMID 2510587 DOI: 10.1002/Ana.410260410  0.369
1989 Hovevey-Sion D, Kopin IJ, Stull RW, Goldstein DS. Effects of monoamine oxidase inhibitors on levels of catechols and homovanillic acid in striatum and plasma. Neuropharmacology. 28: 791-7. PMID 2506486 DOI: 10.1016/0028-3908(89)90169-X  0.357
1989 Garty M, Deka-Starosta A, Chang PC, Eisenhofer G, Zukowska-Grojec Z, Stull R, Kopin IJ, Goldstein DS. Plasma levels of catechols during reflexive changes in sympathetic nerve activity. Neurochemical Research. 14: 523-31. PMID 2503766 DOI: 10.1007/Bf00964913  0.326
1989 Goldstein DS, Eisenhofer G, Garty M, Folio CJ, Stull R, Brush JE, Sax FL, Keiser HR, Kopin IJ. Implications of plasma levels of catechols in the evaluation of sympathoadrenomedullary function. American Journal of Hypertension. 2: 133S-139S. PMID 2493793 DOI: 10.1093/Ajh/2.3.133S  0.351
1988 Szemeredi K, Zukowska-Grojec Z, Bagdy G, Hill J, Kopin IJ. Evidence for a direct peripheral effect of clonidine on the norepinephrine release in vivo in pithed rats. European Journal of Pharmacology. 145: 251-5. PMID 3350046 DOI: 10.1016/0014-2999(88)90426-8  0.389
1988 Goldstein DS, Eisenhofer G, Stull R, Folio CJ, Keiser HR, Kopin IJ. Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans. The Journal of Clinical Investigation. 81: 213-20. PMID 3335637 DOI: 10.1172/Jci113298  0.385
1988 Palombo E, Porrino LJ, Bankiewicz KS, Crane AM, Kopin IJ, Sokoloff L. Administration of MPTP acutely increases glucose utilization in the substantia nigra of primates. Brain Research. 453: 227-34. PMID 3261197 DOI: 10.1016/0006-8993(88)90162-X  0.428
1988 Kopin IJ, Bankiewicz K, Harvey-White J. Effect of MPTP-induced parkinsonism in monkeys on the urinary excretion of HVA and MHPG during debrisoquin administration. Life Sciences. 43: 133-41. PMID 3260652 DOI: 10.1016/0024-3205(88)90290-1  0.357
1988 Brücke T, Bankiewicz K, Harvey-White J, Kopin I. The partial dopamine receptor agonist terguride in the MPTP-induced hemiparkinsonian monkey model. European Journal of Pharmacology. 148: 445-448. PMID 3260191 DOI: 10.1016/0014-2999(88)90125-2  0.329
1988 Schinelli S, Zuddas A, Kopin IJ, Barker JL, di Porzio U. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism and 1-methyl-4-phenylpyridinium uptake in dissociated cell cultures from the embryonic mesencephalon. Journal of Neurochemistry. 50: 1900-7. PMID 3259619 DOI: 10.1111/J.1471-4159.1988.Tb02495.X  0.325
1988 Ho VW, Porrino LJ, Crane AM, Burns RS, Kopin IJ, Sokoloff L. Metabolic mapping of the oculomotor system in MPTP-induced parkinsonian monkeys. Annals of Neurology. 23: 86-9. PMID 3257855 DOI: 10.1002/Ana.410230114  0.464
1988 Eisenhofer G, Goldstein DS, Ropchak TG, Nguyen HQ, Keiser HR, Kopin IJ. Source and physiological significance of plasma 3,4-dihydroxyphenylglycol and 3-methoxy-4-hydroxyphenylglycol. Journal of the Autonomic Nervous System. 24: 1-14. PMID 3209794 DOI: 10.1016/0165-1838(88)90130-0  0.331
1988 Szemeredi K, Bagdy G, Stull R, Keiser HR, Kopin IJ, Goldstein DS. Sympathoadrenomedullary hyper-responsiveness to yohimbine in juvenile spontaneously hypertensive rats. Life Sciences. 43: 1063-8. PMID 3172973 DOI: 10.1016/0024-3205(88)90201-9  0.398
1988 Szemeredi K, Bagdy G, Stull R, Calogero AE, Kopin IJ, Goldstein DS. Sympathoadrenomedullary inhibition by chronic glucocorticoid treatment in conscious rats. Endocrinology. 123: 2585-90. PMID 3168935 DOI: 10.1210/Endo-123-5-2585  0.407
1988 Kopin IJ, White JH, Bankiewicz K. A new approach to biochemical evaluation of brain dopamine metabolism. Cellular and Molecular Neurobiology. 8: 171-9. PMID 3044592 DOI: 10.1007/Bf00711243  0.387
1988 Eisenhofer G, Goldstein DS, Ropchak TG, Kopin IJ. Source and physiological significance of plasma 3,4-dihydroxyphenylalanine in the rat. Journal of Neurochemistry. 51: 1204-13. PMID 2901461 DOI: 10.1111/J.1471-4159.1988.Tb03088.X  0.382
1987 Pohl R, Ettedgui E, Bridges M, Lycaki H, Jimerson D, Kopin I, Rainey JM. Plasma MHPG levels in lactate and isoproterenol anxiety states Biological Psychiatry. 22: 1127-1136. PMID 3651531 DOI: 10.1016/0006-3223(87)90054-0  0.318
1987 Porrino LJ, Burns RS, Crane AM, Palombo E, Kopin IJ, Sokoloff L. Local cerebral metabolic effects of L-dopa therapy in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in monkeys. Proceedings of the National Academy of Sciences of the United States of America. 84: 5995-9. PMID 3497401 DOI: 10.1073/Pnas.84.16.5995  0.497
1987 Porrino LJ, Burns RS, Crane AM, Palombo E, Kopin IJ, Sokoloff L. Changes in local cerebral glucose utilization associated with Parkinson's syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the primate. Life Sciences. 40: 1657-64. PMID 3494179 DOI: 10.1016/0024-3205(87)90014-2  0.415
1987 Goldstein DS, Udelsman R, Eisenhofer G, Stull R, Keiser HR, Kopin IJ. Neuronal source of plasma dihydroxyphenylalanine. The Journal of Clinical Endocrinology and Metabolism. 64: 856-61. PMID 3102548 DOI: 10.1210/Jcem-64-4-856  0.333
1987 Finberg JP, Kopin IJ. Chronic clonidine treatment produces desensitisation of post- but not presynaptic alpha 2-adrenoceptors. European Journal of Pharmacology. 138: 95-100. PMID 3040429 DOI: 10.1016/0014-2999(87)90342-6  0.333
1987 Goldstein DS, Eisenhofer G, Sax FL, Keiser HR, Kopin IJ. Plasma norepinephrine pharmacokinetics during mental challenge. Psychosomatic Medicine. 49: 591-605. PMID 2827219 DOI: 10.1097/00006842-198711000-00004  0.301
1987 Eisenhofer G, Goldstein DS, Stull RW, Gold PW, Keiser HR, Kopin IJ. Dissociation between corticotrophin and catecholamine responses to isoprenaline in humans. Clinical and Experimental Pharmacology & Physiology. 14: 337-41. PMID 2822312 DOI: 10.1111/J.1440-1681.1987.Tb00980.X  0.332
1987 Haass M, Zukowska-Grojec Z, Kopin IJ, Zamir N. Role of autonomic nervous system and vasoactive hormones in the release of atrial natriuretic peptides in conscious rats. Journal of Cardiovascular Pharmacology. 10: 424-32. PMID 2444795 DOI: 10.1097/00005344-198710000-00007  0.383
1986 Siever LJ, Uhde TW, Jimerson DC, Lake CR, Kopin IJ, Murphy DL. Indices of noradrenergic output in depression. Psychiatry Research. 19: 59-73. PMID 3786600 DOI: 10.1016/0165-1781(86)90093-4  0.327
1986 Finberg JP, Kopin IJ. Chronic clorgyline treatment enhances release of norepinephrine following sympathetic stimulation in the rat. Naunyn-Schmiedeberg's Archives of Pharmacology. 332: 236-42. PMID 3713870 DOI: 10.1007/Bf00504860  0.396
1986 Goldstein DS, Zimlichman R, Stull R, Keiser HR, Kopin IJ. Estimation of intrasynaptic norepinephrine concentrations in humans. Hypertension. 8: 471-5. PMID 3710555 DOI: 10.1161/01.Hyp.8.6.471  0.345
1986 Eisenhofer G, Goldstein DS, Stull R, Keiser HR, Sunderland T, Murphy DL, Kopin IJ. Simultaneous liquid-chromatographic determination of 3,4-dihydroxyphenylglycol, catecholamines, and 3,4-dihydroxyphenylalanine in plasma, and their responses to inhibition of monoamine oxidase. Clinical Chemistry. 32: 2030-3. PMID 3096593 DOI: 10.1093/Clinchem/32.11.2030  0.364
1986 Haass M, Zamir N, Goldstein DS, Kopin IJ, Zukowska-Grojec Z. Reduced Release of Atrial Natriuretic Peptides to Acute Volume Expansion in Conscious Young Spontaneously Hypertensive Rats Journal of Cardiovascular Pharmacology. 8: 1327. DOI: 10.1097/00005344-198611000-00198  0.316
1985 Weise VK, Palkovits M, Kopin IJ. Effect of ventral noradrenergic bundle transection and locus coeruleus lesions on urinary 3-methoxy-4-hydroxyphenylethyleneglycol (MHPG) excretion in the rat. Brain Research. 359: 239-45. PMID 4075147 DOI: 10.1016/0006-8993(85)91434-9  0.349
1985 Polinsky RJ, Goldstein DS, Brown RT, Keiser HR, Kopin IJ. Decreased sympathetic neuronal uptake in idiopathic orthostatic hypotension. Annals of Neurology. 18: 48-53. PMID 4037750 DOI: 10.1002/Ana.410180109  0.366
1985 Goldstein DS, Zimlichman R, Stull R, Folio J, Levinson PD, Keiser HR, Kopin IJ. Measurement of regional neuronal removal of norepinephrine in man. The Journal of Clinical Investigation. 76: 15-21. PMID 4019774 DOI: 10.1172/Jci111939  0.348
1985 Zukowska-Grojec Z, Bayorh MA, Kopin IJ, Feuerstein G. Overall and regional hemodynamic effects of leukotriene D4 in spontaneously hypertensive rats. Hypertension. 7: 507-13. PMID 4007988 DOI: 10.1161/01.Hyp.7.4.507  0.33
1985 Zukowska-Grojec Z, Zerbe RL, Jimerson DC, Bayorh MA, Palkovits M, Kopin IJ. Catecholaminergic activity of the baroreceptor areas of the brain in response to bilateral dorsolateral transection of medulla oblongata in rats. Brain Research. 325: 231-40. PMID 3978417 DOI: 10.1016/0006-8993(85)90319-1  0.372
1984 Kopin IJ, Zukowska-Grojec Z, Bayorh MA, Goldstein DS. Estimation of intrasynaptic norepinephrine concentrations at vascular neuroeffector junctions in vivo. Naunyn-Schmiedeberg's Archives of Pharmacology. 325: 298-305. PMID 6728040 DOI: 10.1007/Bf00504372  0.378
1984 Feuerstein G, Bayorh MA, Zerbe RL, Kopin IJ. Peripheral pressor effects of sympathetic stimulation, noradrenaline, angiotensin II and vasopressin in Brattleboro rats. Naunyn-Schmiedeberg's Archives of Pharmacology. 325: 247-50. PMID 6728038 DOI: 10.1007/Bf00495951  0.367
1984 Polinsky RJ, Jimerson DC, Kopin IJ. Chronic autonomic failure: CSF and plasma 3-methoxy-4-hydroxyphenylglycol. Neurology. 34: 979-83. PMID 6539879 DOI: 10.1212/Wnl.34.7.979  0.328
1984 Bayorh MA, Zukowska-Grojec Z, Palkovits M, Kopin IJ. Effect of phencyclidine (PCP) on blood pressure and catecholamine levels in discrete brain nuclei. Brain Research. 321: 315-8. PMID 6498520 DOI: 10.1016/0006-8993(84)90184-7  0.342
1984 Zavadil AP, Ross RJ, Calil HM, Linnoila M, Blombery P, Jimerson DC, Kopin IJ, Potter WZ. The effect of desmethylimipramine on the metabolism of norepinephrine. Life Sciences. 35: 1061-8. PMID 6482645 DOI: 10.1016/0024-3205(84)90070-5  0.327
1984 Martin PR, Ebert MH, Gordon EK, Weingartner H, Kopin IJ. Catecholamine metabolism during clonidine withdrawal. Psychopharmacology. 84: 58-63. PMID 6436892 DOI: 10.1007/Bf00432025  0.376
1984 Feuerstein G, Lozovsky D, Cohen LA, Labroo VM, Kirk KL, Kopin IJ, Faden AI. Differential effect of fluorinated analogs of TRH on the cardiovascular system and prolactin release. Neuropeptides. 4: 303-10. PMID 6433221 DOI: 10.1016/0143-4179(84)90004-0  0.337
1984 Kopin IJ. Avenues of investigation for the role of catecholamines in anxiety. Psychopathology. 17: 83-97. PMID 6369370 DOI: 10.1159/000284081  0.323
1984 Chiueh CC, Markey SP, Burns RS, Johannessen JN, Pert A, Kopin IJ. Neurochemical and behavioral effects of systemic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat. European Journal of Pharmacology. 100: 189-94. PMID 6203759 DOI: 10.1016/0014-2999(84)90221-8  0.38
1984 Martin PR, Weingartner H, Gordon EK, Burns RS, Linnoila M, Kopin IJ, Ebert MH. Central nervous system catecholamine metabolism in Korsakoff's psychosis. Annals of Neurology. 15: 184-7. PMID 6200058 DOI: 10.1002/Ana.410150212  0.33
1984 Martin PR, Ebert MH, Gordon EK, Linnoila M, Kopin IJ. Effects of clonidine on central and peripheral catecholamine metabolism. Clinical Pharmacology and Therapeutics. 35: 322-7. PMID 6199153 DOI: 10.1038/Clpt.1984.37  0.398
1983 Kopin IJ, Polinsky RJ, Oliver JA, Oddershede IR, Ebert MH. Urinary catecholamine metabolites distinguish different types of sympathetic neuronal dysfunction in patients with orthostatic hypotension. The Journal of Clinical Endocrinology and Metabolism. 57: 632-7. PMID 6874892 DOI: 10.1210/Jcem-57-3-632  0.348
1983 Lozovsky D, Saller CF, Bayorh MA, Chiueh CC, Rice KC, Burke TR, Kopin IJ. Effects of phencyclidine on rat prolactin, dopamine receptor and locomotor activity. Life Sciences. 32: 2725-31. PMID 6855468 DOI: 10.1016/0024-3205(83)90392-2  0.403
1983 Kopin IJ, Gordon EK, Jimerson DC, Polinsky RJ. Relation between plasma and cerebrospinal fluid levels of 3-methoxy-4-hydroxyphenylglycol. Science (New York, N.Y.). 219: 73-5. PMID 6849119 DOI: 10.1126/Science.6849119  0.303
1983 Goldstein DS, Lake CR, Chernow B, Ziegler MG, Coleman MD, Taylor AA, Mitchell JR, Kopin IJ, Keiser HR. Age-dependence of hypertensive-normotensive differences in plasma norepinephrine. Hypertension. 5: 100-4. PMID 6848457 DOI: 10.1161/01.Hyp.5.1.100  0.322
1983 Martin PR, Ebert MH, Gordon EK, Kopin IJ. Urinary catecholamine metabolites and effects of clonidine in patients with alcohol amnestic disorder. Clinical Pharmacology and Therapeutics. 33: 19-27. PMID 6848295 DOI: 10.1038/Clpt.1983.3  0.321
1983 Zerbe RL, Bayorh MA, Quirion R, Kopin IJ. The role of vasopressin suppression in phencyclidine-induced diuresis. Pharmacology. 26: 73-8. PMID 6844390 DOI: 10.1159/000137786  0.34
1983 Bayorh MA, Zukowska-Grojec Z, Kopin IJ. Effect of desipramine and cocaine on plasma norepinephrine and pressor responses to adrenergic stimulation in pithed rats. Journal of Clinical Pharmacology. 23: 24-31. PMID 6841657 DOI: 10.1002/J.1552-4604.1983.Tb02700.X  0.399
1983 Ross RJ, Zavadil AP, Calil HM, Linnoila M, Kitanaka I, Blombery P, Kopin IJ, Potter WZ. Effects of desmethylimipramine on plasma norepinephrine, pulse, and blood pressure. Clinical Pharmacology and Therapeutics. 33: 429-37. PMID 6831821 DOI: 10.1038/Clpt.1983.58  0.329
1983 Zukowska-Grojec Z, Bayorh MA, Zerbe RL, Palkovits M, Kopin IJ. Role of catecholamines and vasopressin in cardiovascular responses to bilateral dorsolateral transection of the medulla oblongata in the rat. Hypertension. 5: 908-15. PMID 6654453 DOI: 10.1161/01.Hyp.5.6.908  0.394
1983 Bayorh MA, Lozovsky D, Rice KC, Burke TR, Kopin IJ. Cardiovascular and plasma prolactin responses to stereoisomers of phencyclidine. Pharmacology, Biochemistry, and Behavior. 19: 365-7. PMID 6634885 DOI: 10.1016/0091-3057(83)90066-7  0.327
1983 Goldstein DS, Horwitz D, Keiser HR, Polinsky RJ, Kopin IJ. Plasma l-[3H]norepinephrine, d-[14C]norepinephrine, and d,l-[3H]isoproterenol kinetics in essential hypertension. The Journal of Clinical Investigation. 72: 1748-58. PMID 6630523 DOI: 10.1172/Jci111134  0.363
1983 Williford DJ, Zavadil AP, Walsh RA, Weise V, Kopin IJ, Gillis RA. Influence of vagotomy on changes in feline plasma catecholamine levels induced by occlusion of either the left or right coronary vessel. Cardiovascular Research. 17: 568-76. PMID 6627277 DOI: 10.1093/Cvr/17.9.568  0.356
1983 Feuerstein G, Zukowska-Grojec Z, Bayorh M, Kopin IJ, Faden AI. Leukotriene D4-induced hypotension is reversed by thyrotropin-releasing hormone. Prostaglandins. 26: 711-24. PMID 6422508 DOI: 10.1016/0090-6980(83)90056-4  0.383
1983 Ezra D, Bayorh MA, Zukowska-Grojec Z, Lazar JD, Kopin IJ, Feuerstein G. Effects of chronic arachidonate on blood pressure of spontaneously hypertensive rats. Clinical and Experimental Hypertension. Part a, Theory and Practice. 5: 1485-99. PMID 6416721 DOI: 10.3109/10641968309069506  0.375
1983 Bayorh MA, Zukowska-Grojec Z, Ezra D, Feuerstein GZ, Kopin IJ. Cardiovascular and sympathetic responses to chronic arachidonate in SHR and WKY rats. Hypertension. 5: 172-9. PMID 6402450 DOI: 10.1161/01.Hyp.5.2.172  0.418
1983 Goldstein DS, McCarty R, Polinsky RJ, Kopin IJ. Relationship between plasma norepinephrine and sympathetic neural activity. Hypertension. 5: 552-9. PMID 6345364 DOI: 10.1161/01.Hyp.5.4.552  0.605
1983 Zukowska-Grojec Z, Bayorh MA, Kopin IJ. Effect of desipramine on the effects of alpha-adrenoceptor inhibitors on pressor responses and release of norepinephrine into plasma of pithed rats. Journal of Cardiovascular Pharmacology. 5: 297-301. PMID 6188906 DOI: 10.1097/00005344-198303000-00022  0.331
1982 Saller CF, Zerbe RL, Bayorh MA, Lozovsky D, Kopin IJ. Phencyclidine suppresses plasma prolactin levels. European Journal of Pharmacology. 83: 309-11. PMID 7173312 DOI: 10.1016/0014-2999(82)90267-9  0.387
1982 Lewy AJ, Wehr TA, Rosenthal NE, Nurnberger JI, Siever LJ, Uhde TW, Newsome DA, Becker LE, Markey SP, Kopin IJ, Goodwin FK. Melatonin secretion as a neurobiological "marker" and effects of light in humans. Psychopharmacology Bulletin. 18: 127-9. PMID 7156273  0.357
1982 Bayorh MA, Kopin IJ. Effect of phencyclidine (PCP) on adrenergic responses to spinal cord stimulation in pithed rats. European Journal of Pharmacology. 85: 15-21. PMID 7151861 DOI: 10.1016/0014-2999(82)90419-8  0.432
1982 Feuerstein G, Zukowska-Grojec Z, Krausz MM, Blank ML, Snyder F, Kopin IJ. Cardiovascular and sympathetic effects of l-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine in conscious SHR and WKY rats. Clinical and Experimental Hypertension. Part a, Theory and Practice. 4: 1335-50. PMID 7116669 DOI: 10.3109/10641968209060793  0.408
1982 Zerbe RL, Feuerstein G, Meyer DK, Kopin IJ. Cardiovascular, sympathetic, and renin-angiotensin system responses to hemorrhage in vasopressin-deficient rats. Endocrinology. 111: 608-13. PMID 7047152 DOI: 10.1210/Endo-111-2-608  0.394
1982 Feuerstein G, Adelberg SA, Kopin IJ, Jacobowitz DM. Hypothalamic sites for cardiovascular and sympathetic modulation by prostaglandin E2. Brain Research. 231: 335-42. PMID 6948599 DOI: 10.1016/0006-8993(82)90370-5  0.366
1982 Pfeiffer A, Feuerstein G, Faden A, Kopin IJ. Evidence for an involvement of mu-, but not delta- or kappa-opiate receptors in sympathetically and parasympathetically mediated cardiovascular responses to opiates upon anterior hypothalamic injection. Life Sciences. 31: 1279-82. PMID 6292614 DOI: 10.1016/0024-3205(82)90361-7  0.319
1982 Cohen RM, Campbell IC, Yamaguchi I, Pickar D, Kopin IJ, Murphy DL. Cardiovascular changes in response to selective monoamine oxidase inhibition in the rat. European Journal of Pharmacology. 80: 155-60. PMID 6284529 DOI: 10.1016/0014-2999(82)90193-5  0.375
1982 Bybee DE, Wiesen M, Aronin N, Krieger DT, Frohman LA, Kopin IJ. Failure of bromocriptine to lower plasma catecholamines in normal men and women. The Journal of Clinical Endocrinology and Metabolism. 54: 648-50. PMID 6276434 DOI: 10.1210/Jcem-54-3-648  0.316
1982 Linnoila M, Karoum F, Calil HM, Kopin IJ, Potter WZ. Alteration of norepinephrine metabolism with desipramine and zimelidine in depressed patients. Archives of General Psychiatry. 39: 1025-8. PMID 6214234 DOI: 10.1001/Archpsyc.1982.04290090027006  0.34
1982 Feuerstein G, Zerbe RL, Meyer DK, Kopin IJ. Alteration of cardiovascular, neurogenic, and humoral responses to acute hypovolemic hypotension by administered prostacyclin. Journal of Cardiovascular Pharmacology. 4: 246-53. PMID 6175808 DOI: 10.1097/00005344-198203000-00013  0.404
1982 Feuerstein G, Helke CJ, Zerbe RL, Jacobowitz DM, Kopin IJ. Mechanisms involved in central cardiovascular effects of prostaglandin F2 alpha. The American Journal of Physiology. 242: R545-51. PMID 6123262 DOI: 10.1152/Ajpregu.1982.242.5.R545  0.354
1981 Lake CR, Polinsky RJ, Güllner HG, Ebert MH, Ziegler MG, Bartter FC, Kopin IJ. Dissociation between central and peripheral noradrenergic activity in essential hypertension. Clinical Science (London, England : 1979). 229s-233s. PMID 7449261 DOI: 10.1042/Cs059229S  0.313
1981 Kopin IJ, McCarty R, Yamaguchi I. Plasma catecholamines in human and experimental hypertension. Clinical and Experimental Hypertension. 2: 379-94. PMID 7428562 DOI: 10.3109/10641968009037120  0.65
1981 Feuerstein G, Zerbe RL, Ben-Ishay D, Kopin IJ, Jacobowitz DM. Catecholamines and vasopressin in forebrain nuclei of hypertension prone and resistant rats. Brain Research Bulletin. 7: 671-6. PMID 7326583 DOI: 10.1016/0361-9230(81)90116-7  0.395
1981 Goldstein DS, Feuerstein GZ, Kopin IJ, Keiser HR. Validity of liquid chromatography with electrochemical detection for measuring dopamine in human plasma. Clinica Chimica Acta; International Journal of Clinical Chemistry. 117: 113-20. PMID 7307273 DOI: 10.1016/0009-8981(81)90032-2  0.323
1981 Jimerson DC, Ballenger JC, Lake CR, Post RM, Goodwin FK, Kopin IJ. Plasma and CSF MHPG in normals [proceedings]. Psychopharmacology Bulletin. 17: 86-7. PMID 7232666  0.525
1981 Weinstock M, Zavadil AP, Kopin IJ. Peripheral catecholamines mediate certain responses to central cholinergic receptor stimulation by oxotremorine. Monographs in Neural Sciences. 7: 138-45. PMID 7231435 DOI: 10.1159/000388821  0.369
1981 Feuerstein G, Adelberg SA, Kopin IJ, Jacobowitz DM. Cardiovascular and sympathetic responses to PGF2α injection into hypothalamic nuclei Brain Research Bulletin. 6: 203-207. PMID 7225898 DOI: 10.1016/S0361-9230(81)80048-2  0.382
1981 Feuerstein G, Yamaguchi I, Kopin IJ. Effect of GABA agonist and antagonists on cardiovascular and sympathetic responses in SHR and WKY rats. Clinical and Experimental Hypertension. 3: 207-18. PMID 7215066 DOI: 10.3109/10641968109033661  0.405
1981 Feuerstein G, Jimerson DC, Kopin IJ. Prostaglandins, catecholamines, and cardiovascular responses to hemorrhage. The American Journal of Physiology. 240: R166-74. PMID 7212088 DOI: 10.1152/Ajpregu.1981.240.3.R166  0.385
1981 Saller CF, Kopin IJ. Glucose potentiates haloperidol-induced catalepsy. Life Sciences. 29: 2337-41. PMID 7198706 DOI: 10.1016/0024-3205(81)90568-3  0.31
1981 Jimerson DC, Nurnberger JI, Post RM, Gershon ES, Kopin IJ. Plasma MHPG in rapid cyclers and healthy twins. Archives of General Psychiatry. 38: 1287-90. PMID 7197905 DOI: 10.1001/Archpsyc.1981.01780360103012  0.47
1981 McCarty R, Kvetnansky R, Kopin IJ. Plasma catecholamines in rats: daily variations in basal levels and increments in response to stress. Physiology & Behavior. 26: 27-31. PMID 7195043 DOI: 10.1016/0031-9384(81)90074-3  0.632
1981 Feuerstein G, Adelberg S, Kopin IJ, Jacobowitz DM. Central cardiovascular effects of prostacyclin. Neuropharmacology. 20: 1085-90. PMID 7033813 DOI: 10.1016/0028-3908(81)90100-3  0.358
1981 Zerbe RL, Feurstein G, Kopin IJ. Effect of captopril on cardiovascular, sympathetic and vasopressin responses to hemorrhage. European Journal of Pharmacology. 72: 391-5. PMID 7023956 DOI: 10.1016/0014-2999(81)90583-5  0.346
1981 Feuerstein G, Kopin IJ. Effect of PGD2, PGE2 PGF2 alpha and PGI on blood pressure, heart rate and plasma catecholamine responses to spinal cord stimulation in the rat. Prostaglandins. 21: 189-206. PMID 7012933 DOI: 10.1016/0090-6980(81)90137-4  0.334
1981 Polinsky RJ, Kopin IJ, Ebert MH, Weise V. The adrenal medullary response to hypoglycemia in patients with orthostatic hypotension. The Journal of Clinical Endocrinology and Metabolism. 51: 1401-6. PMID 7002951 DOI: 10.1210/Jcem-51-6-1401  0.31
1981 Feuerstein G, Zukowska-Grojec Z, Kopin IJ. Cardiovascular effects of leukotriene D4 in SHR and WKY rats. European Journal of Pharmacology. 76: 107-10. PMID 6895625 DOI: 10.1016/0014-2999(81)90017-0  0.353
1981 Lozovsky D, Saller CF, Kopin IJ. Dopamine receptor binding is increased in diabetic rats. Science (New York, N.Y.). 214: 1031-3. PMID 6458088 DOI: 10.1126/Science.6458088  0.307
1981 Feuerstein G, Chiueh CC, Kopin IJ. Effect of naloxone on the cardiovascular and sympathetic response to hypovolemic hypotension in the rat. European Journal of Pharmacology. 75: 65-9. PMID 6274657 DOI: 10.1016/0014-2999(81)90347-2  0.378
1981 Torda T, Yamaguchi I, Hirata F, Kopin IJ, Axelrod J. Mepacrine treatment prevents immobilization-induced desensitization of beta-adrenergic receptors in rat hypothalamus and brain stem. Brain Research. 205: 441-4. PMID 6258719 DOI: 10.1016/0006-8993(81)90358-9  0.492
1981 Torda T, Yamaguchi I, Hirata F, Kopin IJ, Axelrod J. Quinacrine-blocked desensitization of adrenoceptors after immobilization stress or repeated injection of isoproterenol in rats. The Journal of Pharmacology and Experimental Therapeutics. 216: 334-8. PMID 6257888  0.373
1981 Yamaguchi I, Torda T, Hirata F, Kopin IJ. Adrenoceptor desensitization after immobilization stress or repeated injection of isoproterenol. The American Journal of Physiology. 240: H691-6. PMID 6112882 DOI: 10.1152/Ajpheart.1981.240.5.H691  0.344
1980 Lake CR, Ziegler MG, Coleman MD, Kopin IJ. Fenfluramine potentiation of antihypertensive effects of thiazides Clinical Pharmacology & Therapeutics. 28: 22-27. PMID 7389251 DOI: 10.1038/Clpt.1980.125  0.306
1980 Potter WZ, Zavadil AP, Kopin IJ, Goodwin FK. Single-dose kinetics predict steady-state concentrations on imipramine and desipramine. Archives of General Psychiatry. 37: 314-20. PMID 7362419 DOI: 10.1001/Archpsyc.1980.01780160084010  0.446
1980 Lake CR, Sternberg DE, van Kammen DP, Ballenger JC, Ziegler MG, Post RM, Kopin IJ, Bunney WE. Schizophrenia: elevated cerebrospinal fluid norepinephrine. Science (New York, N.Y.). 207: 331-3. PMID 7350667 DOI: 10.1126/Science.7350667  0.433
1980 Lewy AJ, Tetsuo M, Markey SP, Goodwin FK, Kopin IJ. Pinealectomy abolishes plasma melatonin in the rat. The Journal of Clinical Endocrinology and Metabolism. 50: 204-5. PMID 7350183 DOI: 10.1210/Jcem-50-1-204  0.537
1980 Weinstock M, Zavadil AP, Muth EA, Crowley WR, O'Donohue TL, Jacobowitz DM, Kopin IJ. Evidence that noradrenaline modulates the increase in striatal dopamine metabolism induced by muscarinic receptor stimulation. European Journal of Pharmacology. 68: 427-35. PMID 7202502 DOI: 10.1016/0014-2999(80)90417-3  0.358
1980 McCarty R, Chiueh CC, Kopin IJ. Differential behavioral responses of spontaneously hypertensive (SHR) and normotensive (WKY) rats to d-amphetamine. Pharmacology, Biochemistry, and Behavior. 12: 53-9. PMID 6445066 DOI: 10.1016/0091-3057(80)90415-3  0.608
1980 McCarty R, Kvetnansky R, Lake CR, Thoa NB, Kopin IJ. Sympatho-adrenal activity of SHR and WKY rats during recovery from forced immobilization. Physiology & Behavior. 21: 951-5. PMID 552087 DOI: 10.1016/0031-9384(78)90171-3  0.633
1980 Weinstock M, Zavadil AP, Kopin IJ. Differential effects of d- and l-propranolol on dopamine turnover stimulated by oxotremorine in striatal and mesolimbic areas of rat brain. European Journal of Pharmacology. 59: 187-93. PMID 527644 DOI: 10.1016/0014-2999(79)90281-4  0.345
1980 McCarty R, Kopin IJ. Stress-induced alterations in plasma catecholamines and behavior of rats: effects of chlorisondamine and bretylium. Behavioral and Neural Biology. 27: 249-65. PMID 518456 DOI: 10.1016/S0163-1047(79)92314-8  0.646
1980 Gross HA, Lake CR, Ebert MH, Ziegler MG, Kopin IJ. Catecholamine metabolism in primary anorexia nervosa. The Journal of Clinical Endocrinology and Metabolism. 49: 805-9. PMID 511970 DOI: 10.1210/Jcem-49-6-805  0.399
1980 Lake CR, Mikkelsen EJ, Rapoport JL, Zavadil AP, Kopin IJ. Effect of imipramine on norepinephrine and blood pressure in enuretic boys. Clinical Pharmacology and Therapeutics. 26: 647-53. PMID 387329 DOI: 10.1002/Cpt1979265647  0.319
1979 Saavedra JM, Kvetnansky R, Kopin IJ. Adrenaline, noradrenaline and dopamine levels in specific brain stem areas of acutely immobilized rats. Brain Research. 160: 271-280. PMID 761066 DOI: 10.1016/0006-8993(79)90424-4  0.356
1979 McCarty R, Kopin IJ. Changes in plasma catecholamines and behavior of rats during the anticipation of footshock. Hormones and Behavior. 11: 248-57. PMID 750353 DOI: 10.1016/0018-506X(78)90052-1  0.63
1979 Kvetnansky R, Sun CL, Lake CR, Thoa N, Torda T, Kopin IJ. Effect of handling and forced immobilization on rat plasma levels of epinephrine, norepinephrine, and dopamine-beta-hydroxylase. Endocrinology. 103: 1868-74. PMID 748021 DOI: 10.1210/Endo-103-5-1868  0.403
1979 McCarty R, Kopin IJ. Sympatho-adrenal medullary activity and behavior during exposure to footshock stress: a comparison of seven rat strains. Physiology & Behavior. 21: 567-72. PMID 740775 DOI: 10.1016/0031-9384(78)90132-4  0.615
1979 McCarty R, Kopin IJ. Patterns of behavioral development in spontaneously hypertensive rats and Wistar-Kyoto normotensive controls. Developmental Psychobiology. 12: 239-43. PMID 571375 DOI: 10.1002/Dev.420120307  0.603
1979 Kim YD, Lake CR, Lees DE, Schuette WH, Bull JM, Weise V, Kopin IJ. Hemodynamic and plasma catecholamine responses to hyperthermic cancer therapy in humans. The American Journal of Physiology. 237: H570-4. PMID 495763 DOI: 10.1152/Ajpheart.1979.237.5.H570  0.341
1979 Lake CR, Ziegler MG, Coleman MD, Kopin IJ. Hydrochlorothiazide-induced sympathetic hyperactivity in hypertensive patients. Clinical Pharmacology and Therapeutics. 26: 428-32. PMID 487689 DOI: 10.1002/Cpt1979264428  0.334
1979 Lake CR, Davis PB, Ziegler M, Kopin IJ. Electrolytes and norepinephrine levels in blood of patients with cystic fibrosis. Clinica Chimica Acta; International Journal of Clinical Chemistry. 92: 141-6. PMID 487568 DOI: 10.1016/0009-8981(79)90107-4  0.315
1979 Weinstock M, Zavadil AP, Chiueh CC, Kopin IJ. The effect of oxotremorine on blood pressure and plasma catecholamines in conscious and anesthetized rats. Life Sciences. 24: 301-9. PMID 431324 DOI: 10.1016/0024-3205(79)90326-6  0.419
1979 Kvetnansky R, McCarty R, Thoa NB, Lake CR, Kopin IJ. Sympatho-adrenal responses of spontaneously hypertensive rats to immobilization stress. The American Journal of Physiology. 236: H457-62. PMID 426081 DOI: 10.1152/Ajpheart.1979.236.3.H457  0.618
1979 Davis GC, Williams AC, Markey SP, Ebert MH, Caine ED, Reichert CM, Kopin IJ. Chronic parkinsonism secondary to intravenous injection of meperidine analogues Psychiatry Research. 1: 249-254. PMID 298352 DOI: 10.1016/0165-1781(79)90006-4  0.31
1979 Brown GL, Hunt RD, Ebert MH, Bunney WE, Kopin IJ. Plasma levels of d-amphetamine in hyperactive children. Serial behavior and motor responses. Psychopharmacology. 62: 133-40. PMID 111276 DOI: 10.1007/Bf00427126  0.322
1979 Elchisak MA, Polinsky RJ, Ebert MH, Powers KJ, Kopin IJ. Contribution of plasma homovanillic acid (HVA) to urine and cerebrospinal fluid HVA in the monkey and its pharmacokinetic disposition. Life Sciences. 23: 2339-47. PMID 104110 DOI: 10.1016/0024-3205(78)90200-X  0.324
1979 Gilad GM, McCarty R, Weise VK, Kopin IJ. Strain differences in the regulation of the sympatho-adrenal system. Brain Research. 176: 380-384. PMID 40669 DOI: 10.1016/0006-8993(79)90993-4  0.519
1979 McCarty R, Gilad GM, Weise VK, Kopin IJ. Strain differences in rat adrenal biosynthetic enzymes and stress-induced increases in plasma catecholamines. Life Sciences. 25: 747-54. PMID 40088 DOI: 10.1016/0024-3205(79)90518-6  0.64
1978 Lake CR, Ziegler MG, Coleman M, Kopin IJ. Lack of correlation of plasma norepinephrine and dopamine-beta-hydroxylase in hypertensive and normotensive subjects. Circulation Research. 41: 865-9. PMID 923037 DOI: 10.1161/01.Res.41.6.865  0.348
1978 McCarty R, Kopin IJ. Pregnancy: its effects on blood pressure, heart rate and sympatho-adrenal activity in spontaneously hypertensive rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 158: 242-4. PMID 674227 DOI: 10.3181/00379727-158-40180  0.578
1978 Kopin IJ, Lake RC, Ziegler M. Plasma levels of norepinephrine. Annals of Internal Medicine. 88: 671-80. PMID 646261 DOI: 10.7326/0003-4819-88-5-671  0.416
1978 McCarty R, Kopin IJ. Alterations in plasma catecholamines and behavior during acute stress in spontaneously hypertensive and Wistar-Kyoto normotensive rats. Life Sciences. 22: 997-1005. PMID 642710 DOI: 10.1016/0024-3205(78)90365-X  0.631
1978 Lake CR, Wood JH, Ziegler MG, Ebert MH, Kopin IJ. Probenecid-induced norepinephrine elevations in plasma and CSF. Archives of General Psychiatry. 35: 237-40. PMID 623510 DOI: 10.1001/Archpsyc.1978.01770260115014  0.361
1978 Grobecker H, Roizen MF, Jacobowitz DM, Kopin IJ. Effect of prolonged treatment with adrenergic neuron blocking drugs on sympathoadrenal reactivity in rats. European Journal of Pharmacology. 46: 125-33. PMID 590325 DOI: 10.1016/0014-2999(77)90248-5  0.391
1978 McCarty R, Chiueh CC, Kopin IJ. Spontaneously hypertensive rats: adrenergic hyperresponsivity to anticipation of electric shock. Behavioral Biology. 23: 180-8. PMID 567059 DOI: 10.1016/S0091-6773(78)91766-2  0.619
1978 McCarty R, Chiueh CC, Kopin IJ. Behavioral and cardiovascular responses of spontaneously hypertensive and normotensive rats to inescapable footshock. Behavioral Biology. 22: 405-10. PMID 564690 DOI: 10.1016/S0091-6773(78)92516-6  0.582
1977 Weise VK, Kopin IJ. Assay of cathecholamines in human plasma: studies of a single isotope radioenzymatic procedure. Life Sciences. 19: 1673-85. PMID 1004129 DOI: 10.1016/0024-3205(76)90073-4  0.321
1977 AL, Foppen FH, Saavfdra JM, Jacobowitz D, Kopin IJ. Effect Of Ngf And Dexamethasone On Phenyl-Ethanolamine-N-Methyl Transferase (Pnmt) Activity In Neonatal Rat Superior Cervical Ganglia Journal of Neurochemistry. 28: 1215-1220. PMID 874482 DOI: 10.1111/J.1471-4159.1977.Tb12312.X  0.315
1977 Grobecker H, Roizen MF, Kopin IJ. Effect of tyramine and guanethidine on dopamine-beta-hydroxylase activity and norepinephrine concentrations in vesicular fraction of the heart and plasma of rats. Life Sciences. 20: 1009-15. PMID 850457 DOI: 10.1016/0024-3205(77)90288-0  0.425
1977 Lake CR, Ziegler MG, Coleman MD, Kopin IJ. Age-adjusted plasma norepinephrine levels are similar in normotensive and hypertensive subjects. The New England Journal of Medicine. 296: 208-9. PMID 831092 DOI: 10.1056/Nejm197701272960408  0.308
1977 Liuzzi A, Foppen FH, Kopin IJ. Stimulation and maintenance by nerve growth factor of phenylethanolamine-N-methyltransferase in superior cervical ganglia of adult rats. Brain Research. 138: 309-315. PMID 589478 DOI: 10.1016/0006-8993(77)90748-X  0.332
1977 Lamprecht F, Richardson JS, Williams RB, Kopin IJ. 6-hydroxydopamine destruction of central adrenergic neurones prevents or reverses developing DOCA-salt hypertension in rats. Journal of Neural Transmission. 40: 149-58. PMID 323422 DOI: 10.1007/Bf01250565  0.346
1977 Wooten GF, Weise VK, Kopin IJ. Norepinephrine synthesis contributes to the accumulation of catecholamines after ligation of rat sciatic nerves. Brain Research. 136: 174-7. PMID 73401 DOI: 10.1016/0006-8993(77)90143-3  0.345
1976 Ziegler MG, Lake CR, Kopin IJ. Plasma noradrenaline increases with age. Nature. 261: 333-335. PMID 1272412 DOI: 10.1038/261333A0  0.341
1976 Kizer JS, Palkovits M, Kopin IJ, Saavedra JM, Brownstein MJ. Lack of effect of various endocrine manipulations on tryptophan hydroxylase activity of individual nuclei of the hypothalamus, limbic system, and midbrain of the rat. Endocrinology. 98: 743-7. PMID 1261494 DOI: 10.1210/Endo-98-3-743  0.366
1976 Ziegler MG, Lake CR, Kopin IJ. Deficient sympathetic nervous response in familial dysautonomia. The New England Journal of Medicine. 294: 630-3. PMID 1246255 DOI: 10.1056/Nejm197603182941202  0.364
1976 Roizen MF, Thoa NB, Moss J, Kopin IJ. Inhibition by cyclopropane of release od norepinephrine, but not dopamine-beta-hydroxylase, from the guinea-pig vas deferens. Anesthesiology. 44: 54-6. PMID 1244775 DOI: 10.1097/00000542-197601000-00012  0.322
1976 Lamprecht F, Jacobowitz DM, Richardson JS, Kopin IJ. Central adrenergic neurons in DOCA-salt hypertension. Journal of Neuroscience Research. 1: 227-34. PMID 1225988 DOI: 10.1002/Jnr.490010304  0.318
1976 Reid JL, Zivin JA, Kopin IJ. Central and peripheral adrenergic mechanisms in the development of deoxycorticosterone-saline hypertension in rats. Circulation Research. 37: 569-79. PMID 1192556 DOI: 10.1161/01.Res.37.5.569  0.432
1976 Palkovits M, Brownstein M, Kizer JS, Saavedra JM, Kopin IJ. Effect of stress on serotonin concentration and tryptophan hydroxylase activity of brain nuclei. Neuroendocrinology. 22: 298-304. PMID 1032978 DOI: 10.1159/000122638  0.315
1976 Roizen MF, Kopin IJ, Thoa NB, Zivin J, Muth EA, Jacobowitz DM. The effect of two anesthetic agents on norepinephrine and dopamine in discrete brain nuclei, fiber tracts, and terminal regions of the rat Brain Research. 110: 515-522. PMID 947471 DOI: 10.1016/0006-8993(76)90862-3  0.379
1976 Lake CR, Ziegler MG, Kopin IJ. Use of plasma norepinephrine for evaluation of sympathetic neuronal function in man. Life Sciences. 18: 1315-25. PMID 933720 DOI: 10.1016/0024-3205(76)90210-1  0.325
1976 Gordon EK, Markey SP, Sherman RL, Kopin IJ. Conjugated 3,4 dihydroxy phenyl acetic acid (DOPAC) in human and monkey cerebrospinal fluid and rat brain and the effects of probenecid treatment. Life Sciences. 18: 1285-92. PMID 819753 DOI: 10.1016/0024-3205(76)90206-X  0.341
1976 Kopin IJ, Kaufman S, Viveros H, Jacobowitz D, Lake CR, Ziegler MG, Lovenberg W, Goodwin FK. NIH conference. Dopamine- -hydroxylase. Basic and clinical studies. Annals of Internal Medicine. 85: 211-23. PMID 782312 DOI: 10.7326/0003-4819-85-2-211  0.536
1976 Grobecker H, Saavedra JM, Roizen MF, Weise V, Kopin IJ, Axelrod J. Peripheral and central catecholaminergic neurons in genetic and experimental hypertension in rats. Clinical Science and Molecular Medicine. Supplement. 3: 377s-380s. PMID 15756 DOI: 10.1042/Cs051377S  0.528
1975 Sattin A, Axelrod J, Kopin IJ, Nauta WJ. Ilya Glezer's Struggle. Science (New York, N.Y.). 187: 902. PMID 17745263 DOI: 10.1126/Science.187.4180.902  0.372
1975 Reid JL, Kopin IJ. Significance of plasma dopamine beta-hydroxylase activity as an index of sympathetic neuronal function. Proceedings of the National Academy of Sciences of the United States of America. 71: 4392-4. PMID 4530990 DOI: 10.1073/Pnas.71.11.4392  0.367
1975 Lamprecht F, Ebert MH, Turek I, Kopin IJ. Serum dopamine-beta-hydroxylase in depressed patients and the effect of electroconvulsive shock treatment. Psychopharmacologia. 40: 241-8. PMID 4445451 DOI: 10.1007/Bf00429418  0.371
1975 Hanbauer I, Jacobowitz DM, Kopin IJ. Effects of vinblastine on noradrenergic axons. British Journal of Pharmacology. 50: 219-25. PMID 4425760 DOI: 10.1111/J.1476-5381.1974.Tb08564.X  0.376
1975 Grobecker H, Roizen MF, Weise V, Saavedra JM, Kopin IJ. Sympathoadrenal medullary activity in young, spontaneously hypertensive rats Nature. 258: 267-267. PMID 1202361 DOI: 10.1038/258267A0  0.332
1975 Kizer JS, Zivin JA, Jacobowitz DM, Kopin IJ. The nyctohemeral rhythm of plasma prolactin: effects of ganglionectomy, pinealectomy, constant light, constant darkness or 6-OH-dopamine administration. Endocrinology. 96: 1230-40. PMID 1168130 DOI: 10.1210/Endo-96-5-1230  0.383
1975 Roizen MF, Weise V, Grobecker H, Kopin IJ. Plasma catechomamines and dopamine-β-hydroxylase activity in spontaneously hypertensive rats Life Sciences. 17: 283-288. PMID 1160501 DOI: 10.1016/0024-3205(75)90516-0  0.365
1975 Roizen MF, Thoa NB, Moss J, Kopin IJ. Inhibition by halothane of release of norepinephrine, but not of dopamine-beta-hydroxylase, from guinea-pig vas deferens. European Journal of Pharmacology. 31: 313-8. PMID 1149793 DOI: 10.1016/0014-2999(75)90054-0  0.335
1975 Roizen MF, Weise V, Moss J, Kopin IJ. Plasma catecholamines: arterial-venous difference and the influence of body temperature. Life Sciences. 16: 1133-43. PMID 1134187 DOI: 10.1016/0024-3205(75)90197-6  0.358
1975 Thoa NB, Wooten GF, Axelrod J, Kopin IJ. On the mechanism of release of norepinephrine from sympathetic nerves induced by depolarizing agents and sympathomimetic drugs. Molecular Pharmacology. 11: 10-8. PMID 1117862  0.376
1975 Palkovits M, Kobayashi RM, Kizer JS, Jacobowitz DM, Kopin IJ. Effects of stress on catecholamines and tyrosine hydroxylase activity of individual hypothalamic nuclei. Neuroendocrinology. 18: 144-53. PMID 241031 DOI: 10.1159/000122394  0.345
1975 Webb JG, Berv KR, Kopin IJ. Induction of dopamine-beta-hydroxylase in superior cervical ganglia in organ culture. Neuropharmacology. 14: 643-8. PMID 170558 DOI: 10.1016/0028-3908(75)90087-8  0.318
1975 Wooten GF, Kopin IJ, Axelrod J. Effects of colchicine and vinblastine on axonal transport and transmitter release in sympathetic nerves. Annals of the New York Academy of Sciences. 253: 528-34. PMID 50036 DOI: 10.1111/J.1749-6632.1975.Tb19226.X  0.434
1974 Kobayashi RM, Kopin IJ. The effects of stress and environmental lighting on histamine in the rat brain Brain Research. 74: 356-359. PMID 4836628 DOI: 10.1016/0006-8993(74)90591-5  0.317
1974 Moss J, Colburn RW, Kopin IJ. Scorpion toxin-induced catecholamine release from synaptosomes. Journal of Neurochemistry. 22: 217-21. PMID 4829948 DOI: 10.1111/J.1471-4159.1974.Tb11582.X  0.314
1974 Colburn RW, Ng LK, Lemberger L, Kopin IJ. Subcellular distribution of delta9-tetrahydrocannabinol in rat brain. Biochemical Pharmacology. 23: 873-7. PMID 4824510 DOI: 10.1016/0006-2952(74)90218-4  0.338
1974 Dubois A, Weise VK, Kopin IJ. Postoperative ileus in the rat: physiopathology, etiology and treatment. Annals of Surgery. 178: 781-6. PMID 4759410 DOI: 10.1097/00000658-197312000-00017  0.306
1974 Roizen MF, Moss J, Henry DP, Kopin IJ. Effects of halothane on plasma catecholamines Anesthesiology. 41: 432-439. PMID 4429212 DOI: 10.1097/00000542-197411000-00005  0.405
1974 Kopin IJ, Miklos P, Kobayashi RM, Jacobowitz DM. Quantitative relationship of catecholamine content and histofluorescence in brain of rats Brain Research. 80: 229-235. PMID 4424761 DOI: 10.1016/0006-8993(74)90687-8  0.314
1974 Thoa NB, Costa JL, Moss J, Kopin IJ. Mechanism of release of norepinephrine from peripheral adrenergic neurones by the calcium ionophores X 537A and A 23187. Life Sciences. 14: 1705-19. PMID 4407496 DOI: 10.1016/0024-3205(74)90272-0  0.305
1974 Kizer JS, Palkovits M, Zivin J, Brownstein M, Saavedra JM, Kopin IJ. The effect of endocrinological manipulations on tyrosine hydroxylase and dopamine-beta-hydroxylase activities in individual hypothalamic nuclei of the adult male rat. Endocrinology. 95: 799-812. PMID 4153111 DOI: 10.1210/Endo-95-3-799  0.353
1974 Kobayashi RM, Palkovits M, Kopin IJ, Jacobowitz DM. Biochemical mapping of noradrenergic nerves arising from the rat locus coeruleus Brain Research. 77: 269-279. PMID 4152793 DOI: 10.1016/0006-8993(74)90790-2  0.31
1974 Dubois A, Kopin IJ, Pettigrew KD, Jacobowitz DM. Chemical and Histochemical Studies of Postoperative Sympathetic Activity in the Digestive Tract in Rats Gastroenterology. 66: 403-407. DOI: 10.1016/S0016-5085(74)80140-X  0.363
1973 Thoa NB, Johnson DG, Kopin IJ. Selective release of newly synthesized norepinephrine in the guinea pig vas deferens during hypogastric nerve stimulation. European Journal of Pharmacology. 15: 29-35. PMID 5161337 DOI: 10.1016/0014-2999(71)90074-4  0.349
1973 Carpenter D, Breese G, Schanberg S, Kopin I. Serotonin and dopamine: distribution and accumulation in Aplysia nervous and non-nervous tissues. The International Journal of Neuroscience. 2: 49-56. PMID 5161303 DOI: 10.3109/00207457109146992  0.526
1973 Lamprecht F, Williams RB, Kopin IJ. Serum dopamine-beta-hydroxylase during development of immobilization-induced hypertension. Endocrinology. 92: 953-6. PMID 4701493 DOI: 10.1210/Endo-92-3-953  0.326
1973 Williams RB, Ng LK, Lamprecht F, Roth K, Kopin IJ. 9 -Tetrahydrocannabinol: a hypotensive effect in rats. Psychopharmacologia. 28: 269-74. PMID 4691001 DOI: 10.1007/Bf00429307  0.347
1973 Vogel SA, Silberstein SD, Berv KR, Kopin IJ. Stimulation-induced release of norepinephrine from rat superior cervical ganglia in vitro. European Journal of Pharmacology. 20: 308-11. PMID 4643453 DOI: 10.1016/0014-2999(72)90191-4  0.329
1973 Ng LK, Chase TN, Colburn RW, Kopin IJ. Release of ( 3 H)dopamine by L-5-hydroxytryptophan. Brain Research. 45: 499-505. PMID 4539008 DOI: 10.1016/0006-8993(72)90478-7  0.37
1973 Wooten GF, Thoa NB, Kopin IJ, Axelrod J. Enhanced release of dopamine -hydroxylase and norepinephrine from sympathetic nerves by dibutyryl cyclic adenosine 3', 5'-monophosphate and theophylline. Molecular Pharmacology. 9: 178-83. PMID 4351235  0.421
1973 Ng LK, Lamprecht F, Williams RB, Kopin IJ. Delta 9 -tetrahydrocannabinol and ethanol: differential effects on sympathetic activity in differing environmental setting. Science (New York, N.Y.). 180: 1368-9. PMID 4350929 DOI: 10.1126/Science.180.4093.1368  0.333
1973 Cramer H, Johnson DG, Hanbauer I, Silberstein SD, Kopin IJ. Accumulation of adenosine 3',5'-monophosphate induced by catecholamines in the rat superior cervical ganglion in vitro. Brain Research. 53: 97-104. PMID 4348905 DOI: 10.1016/0006-8993(73)90769-5  0.381
1973 Hanbauer I, Kopin IJ, Maengwyn-Davies GD, Thoa NB, Weise VK. Effects of vinblastine on catecholamine-biosynthetic enzymes in heart, sympathetic ganglion and adrenal glands of rats. British Journal of Pharmacology. 48: 106-12. PMID 4146761 DOI: 10.1111/J.1476-5381.1973.Tb08227.X  0.343
1973 Lamprecht F, Kvetnansky R, Ng LK, Williams RB, Kopin IJ. Effect of 9 -tetrahydrocannabinol on immobilization-induced changes in rat adrenal medullary enzymes. European Journal of Pharmacology. 21: 249-51. PMID 4144486 DOI: 10.1016/0014-2999(73)90235-5  0.329
1972 Silberstein SD, Johnson DG, Jacobowitz DM, Kopin IJ. Sympathetic reinnervation of the rat iris in organ culture. Proceedings of the National Academy of Sciences of the United States of America. 68: 1121-4. PMID 5288362 DOI: 10.1073/Pnas.68.6.1121  0.324
1972 Colburn RW, Kopin IJ. Effects of reserpine and tyramine on release of norepinephrine from synaptosomes. Biochemical Pharmacology. 21: 733-6. PMID 5021593 DOI: 10.1016/0006-2952(72)90065-2  0.33
1972 Lamprecht F, Eichelman B, Thoa NB, Williams RB, Kopin IJ. Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase. Science (New York, N.Y.). 177: 1214-5. PMID 4403515 DOI: 10.1126/Science.177.4055.1214  0.375
1972 Thoa NB, Wooten GF, Axelrod J, Kopin IJ. Inhibition of release of dopamine- -hydroxylase and norepinephrine from sympathetic nerves by colchicine, vinblastine, or cytochalasin-B (hypogastric nerve stimulation-exocytosis-microtubules-microfilaments-guinea pig). Proceedings of the National Academy of Sciences of the United States of America. 69: 520-2. PMID 4333989 DOI: 10.1073/Pnas.69.2.520  0.494
1972 Silberstein SD, Lemberger L, Klein DC, Axelrod J, Kopin IJ. Induction of adrenal tyrosine hydroxylase in organ culture. Neuropharmacology. 11: 721-6. PMID 4151251 DOI: 10.1016/0028-3908(72)90081-0  0.494
1971 Watanabe AM, Parks LC, Kopin IJ. Modification of the cardiovascular effects of L-dopa by decarboxylase inhibitors Journal of Clinical Investigation. 50: 1322-1328. PMID 5578236 DOI: 10.1172/Jci106611  0.337
1971 Kvetñanský R, Weise VK, Gewirtz GP, Kopin IJ. Synthesis of adrenal catecholamines in rats during and after immobilization stress. Endocrinology. 89: 46-9. PMID 5577135 DOI: 10.1210/Endo-89-1-46  0.377
1971 Kvetnanský R, Silbergeld S, Weise VK, Kopin IJ. Effects of restraint on rat adrenomedullary response to 2-deoxy-D-glucose. Psychopharmacologia. 20: 22-31. PMID 5565744 DOI: 10.1007/Bf00404055  0.322
1971 Kvetnanský R, Gewirtz GP, Weise VK, Kopin IJ. Catecholamine-synthesizing enzymes in the rat adrenal gland during exposure to cold. The American Journal of Physiology. 220: 928-31. PMID 5551148 DOI: 10.1152/Ajplegacy.1971.220.4.928  0.303
1971 Ng KY, Chase TN, Colburn RW, Kopin IJ. Dopamine: stimulation-induced release from central neurons. Science (New York, N.Y.). 172: 487-9. PMID 5550505 DOI: 10.1126/Science.172.3982.487  0.371
1971 Ng KY, Colburn RW, Kopin IJ. Effects of L-dopa on efflux of cerebral monoamines from synaptosomes. Nature. 230: 331-332. PMID 5549411 DOI: 10.1038/230331A0  0.354
1971 Kvetnansky R, Gewirtz GP, Weise VK, Kopin IJ. Effect of hypophysectomy on immobilization-induced elevation of tyrosine hydroxylase and phenylethanolamine-N-methyl transferase in the rat adrenal. Endocrinology. 87: 1323-9. PMID 5482708 DOI: 10.1210/Endo-87-6-1323  0.373
1971 Johnson DG, Thoa NB, Weinshilboum R, Axelrod J, Kopin IJ. Enhanced release of dopamine- -hydroxylase from sympathetic nerves by calcium and phenoxybenzamine and its reversal by prostaglandins. Proceedings of the National Academy of Sciences of the United States of America. 68: 2227-30. PMID 5289380 DOI: 10.1073/Pnas.68.9.2227  0.481
1971 Davis JM, Kopin IJ, Lemberger L, Axelrod J. Effects of urinary pH on amphetamine metabolism. Annals of the New York Academy of Sciences. 179: 493-501. PMID 5285389 DOI: 10.1111/J.1749-6632.1971.Tb46926.X  0.423
1971 Weinshilboum RM, Thoa NB, Johnson DG, Kopin IJ, Axelrod J. Proportional release of norepinephrine and dopamine- -hydroxylase from sympathetic nerves. Science (New York, N.Y.). 174: 1349-51. PMID 5135722 DOI: 10.1126/Science.174.4016.1349  0.494
1971 Chase TN, Breese GR, Gordon EK, Kopin IJ. Catecholamine metabolism in the dog: comparison of intravenously and intraventricularly administered [14C]dopamine and [3H]norepinephrine. Journal of Neurochemistry. 18: 135-40. PMID 5107962 DOI: 10.1111/J.1471-4159.1971.Tb00175.X  0.54
1971 Lemberger L, Tamarkin NR, Axelrod J, Kopin IJ. Delta-9-tetrahydrocannabinol: metabolism and disposition in long-term marihuana smokers. Science (New York, N.Y.). 173: 72-4. PMID 5087483 DOI: 10.1126/Science.173.3991.72  0.465
1971 Lemberger L, Axelrod J, Kopin IJ. Metabolism and disposition of delta-9-tetrahydrocannabinol in man. Pharmacological Reviews. 23: 371-80. PMID 4943951  0.345
1971 Weinshilboum RM, Kvetnansky R, Axelrod J, Kopin IJ. Elevation of serum dopamine-beta-hydroxylase activity with forced immobilization. Nature: New Biology. 230: 287-8. PMID 4930611 DOI: 10.1038/Newbio230287A0  0.509
1971 Lemberger L, Axelrod J, Kopin IJ. The disposition and metabolism of tryptamine and the in vivo formation of 6-hydroxytryptamine in the rabbit. The Journal of Pharmacology and Experimental Therapeutics. 177: 169-76. PMID 4398046  0.351
1971 Kvetñanský R, Gewirtz GP, Weise VK, Kopin IJ. Effect of dibutyryl cyclic-AMP on adrenal catecholamine-synthesizing enzymes in repeatedly immobilized hypophysectomized rats. Endocrinology. 89: 50-5. PMID 4325210 DOI: 10.1210/Endo-89-1-50  0.383
1971 Gewirtz GP, Kvetňanský R, Weise VK, Kopin IJ. Effect of ACTH and Dibutyryl Cyclic AMP on Catecholamine Synthesizing Enzymes in the Adrenals of Hypophysectomized Rats Nature. 230: 462-464. PMID 4324860 DOI: 10.1038/230462A0  0.359
1971 Paul MI, Kvetnanský R, Cramer H, Silbergeld S, Kopin IJ. Immobilization stress induced changes in adrenocortical and medullary cyclic AMP content in the rat. Endocrinology. 88: 338-44. PMID 4322047 DOI: 10.1210/Endo-88-2-338  0.324
1971 Lemberger L, Axelrod J, Kopin IJ. METABOLISM AND DISPOSITION OF TETRAHYDROCANNABINOLS IN NÄIVE SUBJECTS AND CHRONIC MARIJUANA USERS Annals of the New York Academy of Sciences. 191: 142-154. DOI: 10.1111/J.1749-6632.1971.Tb13994.X  0.404
1970 Lemberger L, Silberstein SD, Axelrod J, Kopin IJ. Marihuana: studies on the disposition and metabolism of delta-9-tetrahydrocannabinol in man. Science (New York, N.Y.). 170: 1320-2. PMID 5479011 DOI: 10.1126/Science.170.3964.1320  0.482
1970 Kvetnansky R, Weise VK, Kopin IJ. Elevation of adrenal tyrosine hydroxylase and phenylethanolamine-N-methyl transferase by repeated immobilization of rats. Endocrinology. 87: 744-9. PMID 5453289 DOI: 10.1210/Endo-87-4-744  0.35
1970 Ng KY, Chase TN, Colburn RW, Kopin IJ. L-Dopa-induced release of cerebral monoamines. Science (New York, N.Y.). 170: 76-7. PMID 5452893 DOI: 10.1126/Science.170.3953.76  0.348
1970 Chase TN, Katz RI, Kopin IJ. Effect of diazepam on fate of intracisternally injected serotonin-C14. Neuropharmacology. 9: 103-8. PMID 5441164 DOI: 10.1016/0028-3908(70)90053-5  0.304
1970 Gewirtz GP, Kopin IJ. Release of Dopamine-β-hydroxylase with Norepinephrine during Cat Splenic Nerve Stimulation Nature. 227: 406-407. PMID 4913714 DOI: 10.1038/227406A0  0.32
1970 Breese GR, Kopin IJ, Weise VK. Effects of amphetamine derivatives on brain dopamine and noradrenaline. British Journal of Pharmacology. 38: 537-45. PMID 4909707 DOI: 10.1111/J.1476-5381.1970.Tb10595.X  0.501
1970 Breese GR, Chase TN, Kopin IJ. Effect of monoamine oxidase inhibitors on the disposition of intracisternally administered metaraminol-3H. Biochemical Pharmacology. 19: 525-32. PMID 4396250 DOI: 10.1016/0006-2952(70)90209-1  0.54
1970 LOUIS WJ, KRAUSS KR, KOPIN IJ, SJOERDSMA A. Catecholamine Metabolism in Hypertensive Rats Circulation Research. 27: 589-594. DOI: 10.1161/01.Res.27.4.589  0.427
1969 Schildkraut JJ, Schanberg SM, Breese GR, Kopin IJ. Effects of psychoactive drugs on the metabolism of intracisternally administered serotonin in rat brain. Biochemical Pharmacology. 18: 1971-8. PMID 5811629 DOI: 10.1016/0006-2952(69)90293-7  0.746
1969 Katz RI, Kopin IJ. Release of norepinephrine-3H and serotonin-3H evoked from brain slices by electrical-field stimulation-calcium dependency and the effects of lithium, ouabain and tetrodotoxin. Biochemical Pharmacology. 18: 1835-9. PMID 5811621 DOI: 10.1016/0006-2952(69)90289-5  0.323
1969 Breese GR, Chase TN, Kopin IJ. Metabolism of some phenylethylamines and their beta-hydroxylated analogs in brain. The Journal of Pharmacology and Experimental Therapeutics. 165: 9-13. PMID 5782838  0.411
1969 Chase TN, Katz RI, Kopin IJ. Release of [3H]serotonin from brain slices. Journal of Neurochemistry. 16: 607-15. PMID 5768216 DOI: 10.1111/J.1471-4159.1969.Tb06860.X  0.318
1969 Axelrod J, Kopin IJ. The uptake, storage, release and metabolism of noradrenaline in sympathetic nerves. Progress in Brain Research. 31: 21-32. PMID 4900113 DOI: 10.1016/S0079-6123(08)63224-0  0.403
1969 Schildkraut JJ, Schanberg SM, Kopin IJ, Durell J. Affective disorders and norepinephrine pharmacology. International Psychiatry Clinics. 6: 83-141. PMID 4897536  0.594
1969 Breese GR, Chase TN, Kopin IJ. Metabolism of tyramine-3H and octopamine-3H by rat brain. Biochemical Pharmacology. 18: 863-9. PMID 4389230 DOI: 10.1016/0006-2952(69)90057-4  0.532
1969 Katz RI, Goodwin JS, Kopin IJ. Disposition of neurotransmitters in experimental mouse glioma Life Sciences. 8: 561-569. PMID 4308027 DOI: 10.1016/0024-3205(69)90017-4  0.339
1969 Goodwin JS, Katz RI, Kopin IJ. Effect of bromide on evoked release of monoamines from brain slices and intact atria Nature. 221: 556-557. PMID 4307045 DOI: 10.1038/221556A0  0.31
1969 Katz RI, Kopin IJ. Effect of D-LSD and related compounds on release of norepinephrine-H3 and serotonin-H3 evoked from brain slices by electrical stimulation Pharmacological Research Communications. 1: 54-62. DOI: 10.1016/S0031-6989(69)80024-X  0.33
1968 Schanberg SM, Schildkraut JJ, KrÄ­vánek J, Kopin IJ. Effect of cortical spreading depression on norepinephrine-H3 metabolism in brain stem. Experientia. 24: 909-10. PMID 5709032 DOI: 10.1007/Bf02138647  0.657
1968 Katz RI, Chase TN, Kopin IJ. Evoked release of norepinephrine and serotonin from brain slices: inhibitoon by lithium. Science (New York, N.Y.). 162: 466-7. PMID 5683056 DOI: 10.1126/Science.162.3852.466  0.357
1968 Kopin IJ, Weise VK. Effect of reserpine and metaraminol on excretion of homovanilic acid and 3-methoxy-4-hydroxyphenolglycol in the rat. Biochemical Pharmacology. 17: 1461-4. PMID 5659789 DOI: 10.1016/0006-2952(68)90083-X  0.334
1968 Kopin IJ, Breese GR, Krauss KR, Weise VK. Selective release of newly synthesized norepinephrine from the cat spleen during sympathetic nerve stimulation. The Journal of Pharmacology and Experimental Therapeutics. 161: 271-8. PMID 5650139  0.428
1968 Schanberg SM, Schildkraut JJ, Breese GR, Kopin IJ. Metabolism of normetanephrine-H3 in rat brain--identification of conjugated 3-methoxy-4-hydrophenylglycol as the major metabolite. Biochemical Pharmacology. 17: 247-54. PMID 5647052 DOI: 10.1016/0006-2952(68)90330-4  0.738
1968 Schanberg SM, Breese GR, Schildkraut KK, Gordon EK, Kopin IJ. 3-methoxy-4-hydroxyphenylglycol sulfate in brain and cerebrospinal fluid. Biochemical Pharmacology. 17: 2006-8. PMID 4972145 DOI: 10.1016/0006-2952(68)90119-6  0.465
1968 Chase TN, Breese GR, Carpenter DO, Schanberg SM, Kopin IJ. Stimulation-induced release of serotonin. Advances in Pharmacology. 6: 351-64. PMID 4298804 DOI: 10.1016/S1054-3589(08)61191-6  0.489
1968 Chase TN, Kopin IJ. Stimulus-induced release of substances from olfactory bulb using the push-pull cannula. Nature. 217: 466-467. PMID 4295972 DOI: 10.1038/217466A0  0.304
1967 Nybäck H, Sedvall G, Kopin IJ. Accelerated synthesis of dopamine-C14 from tyrosine-C14 in rat brain after chlorpromazine. Life Sciences. 6: 2307-12. PMID 6060277 DOI: 10.1016/0024-3205(67)90040-9  0.331
1967 Schanberg SM, Schildkraut JJ, Kopin IJ. The effects of pentobarbital on the fate of intracisternally administered norepinephrine-H3. The Journal of Pharmacology and Experimental Therapeutics. 157: 311-8. PMID 6039823  0.629
1967 Chase TN, Breese GR, Kopin IJ. Serotonin release from brain slices by electrical stimulation: regional differences and effect of LSD. Science (New York, N.Y.). 157: 1461-3. PMID 6037863 DOI: 10.1126/Science.157.3795.1461  0.527
1967 Sedvall GC, Kopin IJ. Acceleration of norepinephrine synthesis in the rat submaxillary gland in vivo during sympathetic nerve stimulation. Life Sciences. 6: 45-51. PMID 6030556 DOI: 10.1016/0024-3205(67)90360-8  0.368
1967 Schanberg SM, Schildkraut JJ, Kopin IJ. The effects of psychoactive drugs on norepinephrine-3-H metabolism in brain. Biochemical Pharmacology. 16: 393-9. PMID 6029920 DOI: 10.1016/0006-2952(67)90040-8  0.683
1967 Schildkraut JJ, Schanberg SM, Breese GR, Kopin IJ. Norepinephrine metabolism and drugs used in the affective disorders: a possible mechanism of action. The American Journal of Psychiatry. 124: 600-8. PMID 4383104 DOI: 10.1176/Ajp.124.5.600  0.717
1967 Sedvall GC, Kopin IJ. Influence of sympathetic denervation and nerve impulse activity of tyrosine hydroxylase in the rat submaxillary gland Biochemical Pharmacology. 16: 39-46. DOI: 10.1016/0006-2952(67)90183-9  0.354
1966 Schildkraut JJ, Schanberg SM, Kopin IJ. The effects of lithium ion on H3-norepinephrine metabolism in brain. Life Sciences. 5: 1479-83. PMID 5969204 DOI: 10.1016/0024-3205(66)90221-9  0.658
1966 Baldessarini RJ, Kopin IJ. Tritiated norepinephrine: release from brain slices by electrical stimulation. Science (New York, N.Y.). 152: 1630-1. PMID 4160809 DOI: 10.1126/Science.152.3729.1630  0.344
1965 GLOWINSKI J, KOPIN IJ, AXELROD J. METABOLISM OF (H3)NOREPINEPHRINE IN THE RAT BRAIN. Journal of Neurochemistry. 12: 25-30. PMID 14268510 DOI: 10.1111/J.1471-4159.1965.Tb10247.X  0.515
1965 FISCHER JE, KOPIN IJ, AXELROD J. EVIDENCE FOR EXTRANEURONAL BINDING OF NOREPINEPHRINE. The Journal of Pharmacology and Experimental Therapeutics. 147: 181-5. PMID 14259495  0.316
1964 GLOWINSKI J, AXELROD J, KOPIN IJ, WURTMAN RJ. PHYSIOLOGICAL DISPOSITION OF H3-NOREPINEPHRINE IN THE DEVELOPING RAT. The Journal of Pharmacology and Experimental Therapeutics. 146: 48-53. PMID 14221225  0.432
1964 FISCHER JE, MUSACCHIO J, KOPIN IJ, AXELROD J. EFFECTS OF DENERVATION ON THE UPTAKE AND BETA-HYDROXYLATION OF TYRAMINE IN THE RAT SALIVARY GLAND. Life Sciences. 3: 413-9. PMID 14198482 DOI: 10.1016/0024-3205(64)90201-2  0.473
1964 ROSELL S, AXELROD J, KOPIN IJ. RELEASE OF TRITIATED EPINEPHRINE FOLLOWING SYMPATHETIC NERVE STIMULATION. Nature. 201: 301. PMID 14110461 DOI: 10.1038/201301A0  0.472
1963 Kopin IJ, Gordon EK. Origin of Norepinephrine in the Heart Nature. 199: 1289-1289. PMID 14074596 DOI: 10.1038/1991289A0  0.363
1963 WURTMAN RJ, AXELROD J, KOPIN IJ. UTERINE EPINEPHRINE AND BLOOD FLOW IN PREGNANT AND POSTPARTURIENT RATS. Endocrinology. 73: 501-3. PMID 14068838 DOI: 10.1210/Endo-73-4-501  0.458
1963 ROSELL S, KOPIN IJ, AXELROD J. FATE OF H3-NORADRENALINE IN SKELETAL MUSCLE BEFORE AND FOLLOWING SYMPATHETIC STIMULATION. The American Journal of Physiology. 205: 317-21. PMID 14058108 DOI: 10.1152/Ajplegacy.1963.205.2.317  0.466
1963 KOPIN IJ, AXELROD J. The role of monoamine oxidase in the release and metabolism of norepinephrine. Annals of the New York Academy of Sciences. 107: 848-55. PMID 14034691 DOI: 10.1111/J.1749-6632.1963.Tb13328.X  0.469
1963 WURTMAN RJ, KOPIN IJ, AXELROD J. Thyroid function and the cardiac disposition of catecholamines. Endocrinology. 73: 63-74. PMID 14002085 DOI: 10.1210/Endo-73-1-63  0.506
1962 POTTER LT, AXELROD J, KOPIN IJ. Differential binding and release of norepinephrine and tachyphylaxis. Biochemical Pharmacology. 11: 254-6. PMID 14488294 DOI: 10.1016/0006-2952(62)90082-5  0.429
1962 AXELROD J, GORDON E, HERTTING G, KOPIN IJ, POTTER LT. On the mechanism of tachyphylaxis to tyramine in the isolated rat heart. British Journal of Pharmacology and Chemotherapy. 19: 56-63. PMID 13863453 DOI: 10.1111/J.1476-5381.1962.Tb01426.X  0.496
1961 KOPIN IJ, PARE CM, AXELROD J, WEISSBACH H. The fate of melatonin in animals. The Journal of Biological Chemistry. 236: 3072-5. PMID 14458327  0.326
1961 AXELROD J, KOPIN IJ. Estimation of O-methylated metabolites of catecholamines. Methods in Medical Research. 9: 153-8. PMID 13863456  0.319
1961 LABROSSE EH, AXELROD J, KOPIN IJ, KETY SS. Metabolism of 7-H3-epinephrine-d-bitartrate in normal young men. The Journal of Clinical Investigation. 40: 253-60. PMID 13758034 DOI: 10.1172/Jci104251  0.607
1961 KOPIN IJ, AXELROD J, GORDON E. The metabolic fate of H3-epinephrine and C14-metanephrine in the rat. The Journal of Biological Chemistry. 236: 2109-13. PMID 13753073  0.419
1961 HERTTING G, AXELROD J, KOPIN IJ, WHITBY LG. Lack of uptake of catecholamines after chronic denervation of sympathetic nerves. Nature. 189: 66. PMID 13713809 DOI: 10.1038/189066A0  0.467
1960 KOPIN IJ, PARE CM, AXELROD J, WEISSBACH H. 6-Hydroxylation, the major metabolic pathway for melatonin. Biochimica Et Biophysica Acta. 40: 377-8. PMID 14410952 DOI: 10.1016/0006-3002(60)91374-3  0.428
1960 KOPIN IJ, AXELROD J. Presence of 3-methoxy-4-hydroxy-phenylglycol and metanephrine in phaeochromocytoma tissues. Nature. 185: 788. PMID 14410951 DOI: 10.1038/185788A0  0.436
1960 KOPIN IJ, AXELROD J. 3,4-Dihydroxyphenylglycol, a metabolite of epinephrine. Archives of Biochemistry and Biophysics. 89: 148. PMID 14410950 DOI: 10.1016/0003-9861(60)90026-6  0.469
1959 AXELROD J, KOPIN IJ, MANN JD. 3-Methoxy-4-hydroxyphenylglycol sulfate, a new metabolite of epinephrine and norepinephrine. Biochimica Et Biophysica Acta. 36: 576-7. PMID 13795312  0.376
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