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Noah Zaitlen, Ph.D. - Publications

Affiliations: 
2009 Bioinformatics University of California, San Diego, La Jolla, CA 
Area:
Bioinformatics Biology, Genetics, Computer Science

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pazokitoroudi A, Dahl A, Zaitlen N, Rosset S, Sankararaman S. A scalable and robust variance components method reveals insights into the architecture of gene-environment interactions underlying complex traits. Biorxiv : the Preprint Server For Biology. PMID 38168200 DOI: 10.1101/2023.12.12.571316  0.37
2023 An U, Pazokitoroudi A, Alvarez M, Huang L, Bacanu S, Schork AJ, Kendler K, Pajukanta P, Flint J, Zaitlen N, Cai N, Dahl A, Sankararaman S. Deep learning-based phenotype imputation on population-scale biobank data increases genetic discoveries. Nature Genetics. PMID 37985819 DOI: 10.1038/s41588-023-01558-w  0.36
2023 Fu B, Pazokitoroudi A, Xue A, Anand A, Anand P, Zaitlen N, Sankararaman S. A biobank-scale test of marginal epistasis reveals genome-wide signals of polygenic epistasis. Biorxiv : the Preprint Server For Biology. PMID 37745394 DOI: 10.1101/2023.09.10.557084  0.394
2023 Kachuri L, Mak ACY, Hu D, Eng C, Huntsman S, Elhawary JR, Gupta N, Gabriel S, Xiao S, Keys KL, Oni-Orisan A, Rodríguez-Santana JR, LeNoir MA, Borrell LN, Zaitlen NA, et al. Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture. Nature Genetics. PMID 37231098 DOI: 10.1038/s41588-023-01377-z  0.304
2022 Johnson R, Ding Y, Venkateswaran V, Bhattacharya A, Boulier K, Chiu A, Knyazev S, Schwarz T, Freund M, Zhan L, Burch KS, Caggiano C, Hill B, Rakocz N, Balliu B, ... ... Zaitlen N, et al. Author Correction: Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative. Genome Medicine. 14: 128. PMID 36384576 DOI: 10.1186/s13073-022-01128-5  0.568
2022 Taraszka K, Zaitlen N, Eskin E. Leveraging pleiotropy for joint analysis of genome-wide association studies with per trait interpretations. Plos Genetics. 18: e1010447. PMID 36342933 DOI: 10.1371/journal.pgen.1010447  0.601
2022 Thompson M, Gordon MG, Lu A, Tandon A, Halperin E, Gusev A, Ye CJ, Balliu B, Zaitlen N. Multi-context genetic modeling of transcriptional regulation resolves novel disease loci. Nature Communications. 13: 5704. PMID 36171194 DOI: 10.1038/s41467-022-33212-0  0.584
2022 Johnson R, Ding Y, Venkateswaran V, Bhattacharya A, Boulier K, Chiu A, Knyazev S, Schwarz T, Freund M, Zhan L, Burch KS, Caggiano C, Hill B, Rakocz N, Balliu B, ... ... Zaitlen N, et al. Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative. Genome Medicine. 14: 104. PMID 36085083 DOI: 10.1186/s13073-022-01106-x  0.59
2022 Perez RK, Gordon MG, Subramaniam M, Kim MC, Hartoularos GC, Targ S, Sun Y, Ogorodnikov A, Bueno R, Lu A, Thompson M, Rappoport N, Dahl A, Lanata CM, Matloubian M, ... ... Zaitlen N, et al. Single-cell RNA-seq reveals cell type-specific molecular and genetic associations to lupus. Science (New York, N.Y.). 376: eabf1970. PMID 35389781 DOI: 10.1126/science.abf1970  0.498
2021 Lin M, Park DS, Zaitlen NA, Henn BM, Gignoux CR. Admixed Populations Improve Power for Variant Discovery and Portability in Genome-Wide Association Studies. Frontiers in Genetics. 12: 673167. PMID 34108994 DOI: 10.3389/fgene.2021.673167  0.301
2021 Sheppard B, Rappoport N, Loh PR, Sanders SJ, Zaitlen N, Dahl A. A model and test for coordinated polygenic epistasis in complex traits. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33833052 DOI: 10.1073/pnas.1922305118  0.305
2021 Stern AJ, Speidel L, Zaitlen NA, Nielsen R. Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies. American Journal of Human Genetics. PMID 33440170 DOI: 10.1016/j.ajhg.2020.12.005  0.308
2020 Rau CD, Gonzales NM, Bloom JS, Park D, Ayroles J, Palmer AA, Lusis AJ, Zaitlen N. Modeling epistasis in mice and yeast using the proportion of two or more distinct genetic backgrounds: Evidence for "polygenic epistasis". Plos Genetics. 16: e1009165. PMID 33104702 DOI: 10.1371/journal.pgen.1009165  0.326
2020 Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, et al. Author Correction: Multiplexed droplet single-cell RNA-sequencing using natural genetic variation. Nature Biotechnology. PMID 33057163 DOI: 10.1038/s41587-020-0715-9  0.489
2020 Mandric I, Rotman J, Yang HT, Strauli N, Montoya DJ, Van Der Wey W, Ronas JR, Statz B, Yao D, Petrova V, Zelikovsky A, Spreafico R, Shifman S, Zaitlen N, Rossetti M, et al. Author Correction: Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing. Nature Communications. 11: 4499. PMID 32887888 DOI: 10.1038/S41467-020-18509-2  0.504
2020 Dahl A, Zaitlen N. Genetic Influences on Disease Subtypes. Annual Review of Genomics and Human Genetics. 21: 413-435. PMID 32873077 DOI: 10.1146/Annurev-Genom-120319-095026  0.355
2020 Liu X, Mefford JA, Dahl A, He Y, Subramaniam M, Battle A, Price AL, Zaitlen N. GBAT: a gene-based association test for robust detection of trans-gene regulation. Genome Biology. 21: 211. PMID 32831138 DOI: 10.1186/S13059-020-02120-1  0.374
2020 Keys KL, Mak ACY, White MJ, Eckalbar WL, Dahl AW, Mefford J, Mikhaylova AV, Contreras MG, Elhawary JR, Eng C, Hu D, Huntsman S, Oh SS, Salazar S, Lenoir MA, ... ... Zaitlen N, et al. On the cross-population generalizability of gene expression prediction models. Plos Genetics. 16: e1008927. PMID 32797036 DOI: 10.1371/Journal.Pgen.1008927  0.338
2020 Mandric I, Rotman J, Yang HT, Strauli N, Montoya DJ, Van Der Wey W, Ronas JR, Statz B, Yao D, Petrova V, Zelikovsky A, Spreafico R, Shifman S, Zaitlen N, Rossetti M, et al. Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing. Nature Communications. 11: 3126. PMID 32561710 DOI: 10.1038/S41467-020-16857-7  0.515
2020 Mefford J, Park D, Zheng Z, Ko A, Ala-Korpela M, Laakso M, Pajukanta P, Yang J, Witte J, Zaitlen N. Efficient Estimation and Applications of Cross-Validated Genetic Predictions to Polygenic Risk Scores and Linear Mixed Models. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. PMID 32077750 DOI: 10.1089/Cmb.2019.0325  0.305
2020 Dahl A, Nguyen K, Cai N, Gandal MJ, Flint J, Zaitlen N. A Robust Method Uncovers Significant Context-Specific Heritability in Diverse Complex Traits. American Journal of Human Genetics. 106: 71-91. PMID 31901249 DOI: 10.1016/J.Ajhg.2019.11.015  0.428
2019 Gallois A, Mefford J, Ko A, Vaysse A, Julienne H, Ala-Korpela M, Laakso M, Zaitlen N, Pajukanta P, Aschard H. A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context. Nature Communications. 10: 4788. PMID 31636271 DOI: 10.1038/S41467-019-12703-7  0.399
2019 Hernandez RD, Uricchio LH, Hartman K, Ye C, Dahl A, Zaitlen N. Ultrarare variants drive substantial cis heritability of human gene expression. Nature Genetics. 51: 1349-1355. PMID 31477931 DOI: 10.1038/S41588-019-0487-7  0.592
2019 Dahl A, Cai N, Ko A, Laakso M, Pajukanta P, Flint J, Zaitlen N. Reverse GWAS: Using genetics to identify and model phenotypic subtypes. Plos Genetics. 15: e1008009. PMID 30951530 DOI: 10.1371/Journal.Pgen.1008009  0.443
2019 Aschard H, Laville V, Tchetgen ET, Knights D, Imhann F, Seksik P, Zaitlen N, Silverberg MS, Cosnes J, Weersma RK, Xavier R, Beaugerie L, Skurnik D, Sokol H. Genetic effects on the commensal microbiota in inflammatory bowel disease patients. Plos Genetics. 15: e1008018. PMID 30849075 DOI: 10.1371/Journal.Pgen.1008018  0.425
2019 Lea A, Subramaniam M, Ko A, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Mononen N, Raitakari OT, Ala-Korpela M, Pajukanta P, Zaitlen N, Ayroles JF. Genetic and environmental perturbations lead to regulatory decoherence. Elife. 8. PMID 30834892 DOI: 10.7554/Elife.40538  0.405
2019 Dahl A, Guillemot V, Mefford J, Aschard H, Zaitlen N. Adjusting for Principal Components of Molecular Phenotypes Induces Replicating False Positives. Genetics. PMID 30692194 DOI: 10.1534/Genetics.118.301768  0.434
2019 Lea A, Subramaniam M, Ko A, Lehtimäki T, Raitoharju E, Kähönen M, Seppälä I, Mononen N, Raitakari OT, Ala-Korpela M, Pajukanta P, Zaitlen N, Ayroles JF. Author response: Genetic and environmental perturbations lead to regulatory decoherence Elife. DOI: 10.7554/Elife.40538.030  0.337
2018 Galinsky KJ, Reshef YA, Finucane HK, Loh PR, Zaitlen N, Patterson NJ, Brown BC, Price AL. Estimating cross-population genetic correlations of causal effect sizes. Genetic Epidemiology. PMID 30474154 DOI: 10.1002/Gepi.22173  0.412
2018 Kang EY, Lee CH, Furlotte NA, Joo JWJ, Kostem E, Zaitlen N, Eskin E, Han B. An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures. Genetics. PMID 29752291 DOI: 10.1534/Genetics.117.300501  0.715
2018 Mangul S, Yang HT, Strauli N, Gruhl F, Porath HT, Hsieh K, Chen L, Daley T, Christenson S, Wesolowska-Andersen A, Spreafico R, Rios C, Eng C, Smith AD, Hernandez RD, ... ... Zaitlen N, et al. ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues. Genome Biology. 19: 36. PMID 29548336 DOI: 10.1186/S13059-018-1403-7  0.519
2018 Mak AC, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, ... ... Zaitlen N, et al. Whole Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. American Journal of Respiratory and Critical Care Medicine. PMID 29509491 DOI: 10.1164/Rccm.201712-2529Oc  0.426
2018 Peterson RE, Cai N, Dahl AW, Bigdeli TB, Edwards AC, Webb BT, Bacanu SA, Zaitlen N, Flint J, Kendler KS. Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression. The American Journal of Psychiatry. appiajp201717060621. PMID 29495898 DOI: 10.1016/J.Euroneuro.2017.08.023  0.306
2018 Boettcher M, Tian R, Blau JA, Markegard E, Wagner RT, Wu D, Mo X, Biton A, Zaitlen N, Fu H, McCormick F, Kampmann M, McManus MT. Dual gene activation and knockout screen reveals directional dependencies in genetic networks. Nature Biotechnology. PMID 29334369 DOI: 10.1038/Nbt.4062  0.35
2018 Gianfrancesco MA, Glicksberg BS, Dahl A, Lanata C, Kay J, Nititham J, Taylor K, Paranjpe I, Zaitlen N, Sirota M, Criswell L, Schmajuk G, Yazdany J. BD-06 Identification of systemic lupus erythematosus subgroups using electronic health record and genetic databases Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Lsm.30  0.402
2017 Kang HM, Subramaniam M, Targ S, Nguyen M, Maliskova L, McCarthy E, Wan E, Wong S, Byrnes L, Lanata CM, Gate RE, Mostafavi S, Marson A, Zaitlen N, Criswell LA, et al. Multiplexed droplet single-cell RNA-sequencing using natural genetic variation. Nature Biotechnology. PMID 29227470 DOI: 10.1038/Nbt.4042  0.565
2017 Park DS, Eskin I, Kang EY, Gamazon ER, Eng C, Gignoux CR, Galanter JM, Burchard E, Ye CJ, Aschard H, Eskin E, Halperin E, Zaitlen N. An ancestry-based approach for detecting interactions. Genetic Epidemiology. PMID 29114909 DOI: 10.1002/Gepi.22087  0.722
2017 Aschard H, Guillemot V, Vilhjalmsson B, Patel CJ, Skurnik D, Ye CJ, Wolpin B, Kraft P, Zaitlen N. Covariate selection for association screening in multiphenotype genetic studies. Nature Genetics. PMID 29038595 DOI: 10.1038/Ng.3975  0.61
2017 Wagle M, Nguyen J, Lee S, Zaitlen N, Guo S. Heritable natural variation of an anxiety-like behavior in larval zebrafish. Journal of Neurogenetics. 1-11. PMID 28678579 DOI: 10.1080/01677063.2017.1343827  0.318
2017 Hoffman JD, Graff RE, Emami NC, Tai CG, Passarelli MN, Hu D, Huntsman S, Hadley D, Leong L, Majumdar A, Zaitlen N, Ziv E, Witte JS. Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk. Plos Genetics. 13: e1006690. PMID 28362817 DOI: 10.1371/Journal.Pgen.1006690  0.331
2017 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation. Nature Methods. 14: 218-219. PMID 28245214 DOI: 10.1038/Nmeth.4190  0.478
2017 Rahmani E, Yedidim R, Shenhav L, Schweiger R, Weissbrod O, Zaitlen N, Halperin E. GLINT: a user-friendly toolset for the analysis of high-throughput DNA-methylation array data. Bioinformatics (Oxford, England). PMID 28177067 DOI: 10.1093/Bioinformatics/Btx059  0.304
2017 Rahmani E, Shenhav L, Schweiger R, Yousefi P, Huen K, Eskenazi B, Eng C, Huntsman S, Hu D, Galanter J, Oh SS, Waldenberger M, Strauch K, Grallert H, Meitinger T, ... ... Zaitlen N, et al. Genome-wide methylation data mirror ancestry information. Epigenetics & Chromatin. 10: 1. PMID 28149326 DOI: 10.1186/S13072-016-0108-Y  0.38
2017 Galanter JM, Gignoux CR, Oh SS, Torgerson D, Pino-Yanes M, Thakur N, Eng C, Hu D, Huntsman S, Farber HJ, Avila PC, Brigino-Buenaventura E, LeNoir MA, Meade K, Serebrisky D, ... ... Zaitlen N, et al. Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures. Elife. 6. PMID 28044981 DOI: 10.7554/Elife.20532  0.39
2016 Traglia M, Bseiso D, Gusev A, Adviento B, Park DS, Mefford JA, Zaitlen N, Weiss LA. Genetic Mechanisms Leading to Sex Differences Across Common Diseases and Anthropometric Traits. Genetics. PMID 27974502 DOI: 10.1534/Genetics.116.193623  0.433
2016 Zaitlen N, Huntsman S, Hu D, Spear M, Eng C, Oh SS, White MJ, Mak A, Davis A, Meade K, Brigino-Buenaventura E, LeNoir MA, Bibbins-Domingo K, Burchard EG, Halperin E. The Effects of Migration and Assortative Mating on Admixture Linkage Disequilibrium. Genetics. PMID 27879348 DOI: 10.1534/Genetics.116.192138  0.343
2016 Mitra I, Tsang K, Ladd-Acosta C, Croen LA, Aldinger KA, Hendren RL, Traglia M, Lavillaureix A, Zaitlen N, Oldham MC, Levitt P, Nelson S, Amaral DG, Herz-Picciotto I, Fallin MD, et al. Pleiotropic Mechanisms Indicated for Sex Differences in Autism. Plos Genetics. 12: e1006425. PMID 27846226 DOI: 10.1371/Journal.Pgen.1006425  0.383
2016 Joshi RS, Garg P, Zaitlen N, Lappalainen T, Watson CT, Azam N, Ho D, Li X, Antonarakis SE, Brunner HG, Buiting K, Cheung SW, Coffee B, Eggermann T, Francis D, et al. DNA Methylation Profiling of Uniparental Disomy Subjects Provides a Map of Parental Epigenetic Bias in the Human Genome. American Journal of Human Genetics. PMID 27569549 DOI: 10.1016/J.Ajhg.2016.06.032  0.327
2016 Brown BC, Ye CJ, Price AL, Zaitlen N. Transethnic Genetic-Correlation Estimates from Summary Statistics. American Journal of Human Genetics. PMID 27321947 DOI: 10.1016/J.Ajhg.2016.05.001  0.632
2016 Uricchio LH, Zaitlen NA, Ye CJ, Witte JS, Hernandez RD. Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants. Genome Research. PMID 27197206 DOI: 10.1101/Gr.202440.115  0.559
2016 Brown BC, Price AL, Patsopoulos NA, Zaitlen N. Local Joint Testing Improves Power and Identifies Hidden Heritability in Association Studies. Genetics. PMID 27182951 DOI: 10.1534/Genetics.116.188292  0.483
2016 Rahmani E, Zaitlen N, Baran Y, Eng C, Hu D, Galanter J, Oh S, Burchard EG, Eskin E, Zou J, Halperin E. Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies. Nature Methods. PMID 27018579 DOI: 10.1038/Nmeth.3809  0.54
2016 Balliu B, Zaitlen N. A Novel Test for Detecting SNP-SNP Interactions in Case-Only Trio Studies. Genetics. PMID 26865367 DOI: 10.1534/Genetics.115.179846  0.362
2015 Zou JY, Park DS, Burchard EG, Torgerson DG, Pino-Yanes M, Song YS, Sankararaman S, Halperin E, Zaitlen N. Genetic and socioeconomic study of mate choice in Latinos reveals novel assortment patterns. Proceedings of the National Academy of Sciences of the United States of America. 112: 13621-6. PMID 26483472 DOI: 10.1073/Pnas.1501741112  0.464
2015 Caswell JL, Camarda R, Zhou AY, Huntsman S, Hu D, Brenner SE, Zaitlen N, Goga A, Ziv E. Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors. Human Molecular Genetics. PMID 26472073 DOI: 10.1093/Hmg/Ddv432  0.364
2015 Vilhjálmsson BJ, Yang J, Finucane HK, Gusev A, Lindström S, Ripke S, Genovese G, Loh PR, Bhatia G, Do R, Hayeck T, Won HH, Kathiresan S, ... ... Zaitlen N, et al. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American Journal of Human Genetics. 97: 576-592. PMID 26430803 DOI: 10.1016/J.Ajhg.2015.09.001  0.312
2015 Park DS, Brown B, Eng C, Huntsman S, Hu D, Torgerson DG, Burchard EG, Zaitlen N. Adapt-Mix: learning local genetic correlation structure improves summary statistics-based analyses. Bioinformatics (Oxford, England). 31: i181-i189. PMID 26072481 DOI: 10.1093/Bioinformatics/Btv230  0.448
2015 Park DS, Baran Y, Hormozdiari F, Eng C, Torgerson DG, Burchard EG, Zaitlen N. PIGS: improved estimates of identity-by-descent probabilities by probabilistic IBD graph sampling. Bmc Bioinformatics. 16: S9. PMID 25860540 DOI: 10.1186/1471-2105-16-S5-S9  0.384
2015 Cornelis MC, Zaitlen N, Hu FB, Kraft P, Price AL. Genetic and environmental components of family history in type 2 diabetes. Human Genetics. 134: 259-67. PMID 25543539 DOI: 10.1007/S00439-014-1519-0  0.361
2015 Aschard H, Zaitlen N, Lindström S, Kraft P. Variation in predictive ability of common genetic variants by established strata: the example of breast cancer and age. Epidemiology (Cambridge, Mass.). 26: 51-8. PMID 25380502 DOI: 10.1097/Ede.0000000000000195  0.318
2014 Ye CJ, Feng T, Kwon HK, Raj T, Wilson MT, Asinovski N, McCabe C, Lee MH, Frohlich I, Paik HI, Zaitlen N, Hacohen N, Stranger B, De Jager P, Mathis D, et al. Intersection of population variation and autoimmunity genetics in human T cell activation. Science (New York, N.Y.). 345: 1254665. PMID 25214635 DOI: 10.1126/Science.1254665  0.519
2014 Pasaniuc B, Zaitlen N, Shi H, Bhatia G, Gusev A, Pickrell J, Hirschhorn J, Strachan DP, Patterson N, Price AL. Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics (Oxford, England). 30: 2906-14. PMID 24990607 DOI: 10.1093/Bioinformatics/Btu416  0.448
2014 Zhao W, Pollack JL, Blagev DP, Zaitlen N, McManus MT, Erle DJ. Massively parallel functional annotation of 3' untranslated regions. Nature Biotechnology. 32: 387-91. PMID 24633241 DOI: 10.1038/Nbt.2851  0.35
2014 Chimusa ER, Zaitlen N, Daya M, Möller M, van Helden PD, Mulder NJ, Price AL, Hoal EG. Genome-wide association study of ancestry-specific TB risk in the South African Coloured population. Human Molecular Genetics. 23: 796-809. PMID 24057671 DOI: 10.1093/Hmg/Ddt462  0.403
2013 Gusev A, Bhatia G, Zaitlen N, Vilhjalmsson BJ, Diogo D, Stahl EA, Gregersen PK, Worthington J, Klareskog L, Raychaudhuri S, Plenge RM, Pasaniuc B, Price AL. Quantifying missing heritability at known GWAS loci. Plos Genetics. 9: e1003993. PMID 24385918 DOI: 10.1371/Journal.Pgen.1003993  0.406
2013 Zaitlen N, Kraft P, Patterson N, Pasaniuc B, Bhatia G, Pollack S, Price AL. Using extended genealogy to estimate components of heritability for 23 quantitative and dichotomous traits. Plos Genetics. 9: e1003520. PMID 23737753 DOI: 10.1371/Journal.Pgen.1003520  0.45
2013 Pasaniuc B, Sankararaman S, Torgerson DG, Gignoux C, Zaitlen N, Eng C, Rodriguez-Cintron W, Chapela R, Ford JG, Avila PC, Rodriguez-Santana J, Chen GK, Le Marchand L, Henderson B, Reich D, et al. Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics (Oxford, England). 29: 1407-15. PMID 23572411 DOI: 10.1093/Bioinformatics/Btt166  0.365
2013 Aschard H, Zaitlen N, Tamimi RM, Lindström S, Kraft P. A nonparametric test to detect quantitative trait loci where the phenotypic distribution differs by genotypes. Genetic Epidemiology. 37: 323-33. PMID 23512279 DOI: 10.1002/Gepi.21716  0.484
2012 Zaitlen N, Lindström S, Pasaniuc B, Cornelis M, Genovese G, Pollack S, Barton A, Bickeböller H, Bowden DW, Eyre S, Freedman BI, Friedman DJ, Field JK, Groop L, Haugen A, et al. Informed conditioning on clinical covariates increases power in case-control association studies. Plos Genetics. 8: e1003032. PMID 23144628 DOI: 10.1371/Journal.Pgen.1003032  0.357
2012 Zaitlen N, Kraft P. Heritability in the genome-wide association era. Human Genetics. 131: 1655-64. PMID 22821350 DOI: 10.1007/S00439-012-1199-6  0.462
2012 Pasaniuc B, Rohland N, McLaren PJ, Garimella K, Zaitlen N, Li H, Gupta N, Neale BM, Daly MJ, Sklar P, Sullivan PF, Bergen S, Moran JL, Hultman CM, Lichtenstein P, et al. Extremely low-coverage sequencing and imputation increases power for genome-wide association studies. Nature Genetics. 44: 631-5. PMID 22610117 DOI: 10.1038/Ng.2283  0.454
2012 Zaitlen N, Pasaniuc B, Patterson N, Pollack S, Voight B, Groop L, Altshuler D, Henderson BE, Kolonel LN, Le Marchand L, Waters K, Haiman CA, Stranger BE, Dermitzakis ET, Kraft P, et al. Analysis of case-control association studies with known risk variants. Bioinformatics (Oxford, England). 28: 1729-37. PMID 22556366 DOI: 10.1093/Bioinformatics/Bts259  0.42
2011 Aschard H, Qiu W, Pasaniuc B, Zaitlen N, Cho MH, Carey V. Combining effects from rare and common genetic variants in an exome-wide association study of sequence data. Bmc Proceedings. 5: S44. PMID 22373328 DOI: 10.1186/1753-6561-5-S9-S44  0.484
2011 He D, Zaitlen N, Pasaniuc B, Eskin E, Halperin E. Genotyping common and rare variation using overlapping pool sequencing. Bmc Bioinformatics. 12: S2. PMID 21989232 DOI: 10.1186/1471-2105-12-S6-S2  0.638
2011 Bhatia G, Patterson N, Pasaniuc B, Zaitlen N, Genovese G, Pollack S, Mallick S, Myers S, Tandon A, Spencer C, Palmer CD, Adeyemo AA, Akylbekova EL, Cupples LA, Divers J, et al. Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection. American Journal of Human Genetics. 89: 368-81. PMID 21907010 DOI: 10.1016/J.Ajhg.2011.07.025  0.386
2011 Pasaniuc B, Zaitlen N, Lettre G, Chen GK, Tandon A, Kao WH, Ruczinski I, Fornage M, Siscovick DS, Zhu X, Larkin E, Lange LA, Cupples LA, Yang Q, Akylbekova EL, et al. Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. Plos Genetics. 7: e1001371. PMID 21541012 DOI: 10.1371/Journal.Pgen.1001371  0.428
2011 Paşaniuc B, Zaitlen N, Halperin E. Accurate estimation of expression levels of homologous genes in RNA-seq experiments. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 18: 459-68. PMID 21385047 DOI: 10.1089/Cmb.2010.0259  0.329
2010 Zaitlen N, Eskin E. Imputation aware meta-analysis of genome-wide association studies. Genetic Epidemiology. 34: 537-42. PMID 20717975 DOI: 10.1002/Gepi.20507  0.635
2010 Santana R, Mendiburu A, Zaitlen N, Eskin E, Lozano JA. Multi-marker tagging single nucleotide polymorphism selection using estimation of distribution algorithms. Artificial Intelligence in Medicine. 50: 193-201. PMID 20650616 DOI: 10.1016/J.Artmed.2010.05.010  0.561
2010 Price AL, Zaitlen NA, Reich D, Patterson N. New approaches to population stratification in genome-wide association studies. Nature Reviews. Genetics. 11: 459-63. PMID 20548291 DOI: 10.1038/Nrg2813  0.363
2010 Kang HM, Zaitlen NA, Eskin E. EMINIM: an adaptive and memory-efficient algorithm for genotype imputation. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 17: 547-60. PMID 20377463 DOI: 10.1089/Cmb.2009.0199  0.596
2010 Kang HM, Sul JH, Service SK, Zaitlen NA, Kong SY, Freimer NB, Sabatti C, Eskin E. Variance component model to account for sample structure in genome-wide association studies. Nature Genetics. 42: 348-54. PMID 20208533 DOI: 10.1038/Ng.548  0.737
2010 Zaitlen N, Paşaniuc B, Gur T, Ziv E, Halperin E. Leveraging genetic variability across populations for the identification of causal variants. American Journal of Human Genetics. 86: 23-33. PMID 20085711 DOI: 10.1016/J.Ajhg.2009.11.016  0.473
2009 Smith EN, Bloss CS, Badner JA, Barrett T, Belmonte PL, Berrettini W, Byerley W, Coryell W, Craig D, Edenberg HJ, Eskin E, Foroud T, Gershon E, Greenwood TA, Hipolito M, ... ... Zaitlen N, et al. Genome-wide association study of bipolar disorder in European American and African American individuals. Molecular Psychiatry. 14: 755-63. PMID 19488044 DOI: 10.1038/Mp.2009.43  0.577
2009 Zaitlen N, Kang HM, Eskin E. Linkage effects and analysis of finite sample errors in the HapMap. Human Heredity. 68: 73-86. PMID 19365134 DOI: 10.1159/000212500  0.615
2009 Kang HM, Zaitlen NA, Han B, Eskin E. An adaptive and memory efficient algorithm for genotype imputation Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5541: 482-495. DOI: 10.1007/978-3-642-02008-7_34  0.598
2008 Han B, Kang HM, Seo MS, Zaitlen N, Eskin E. Efficient association study design via power-optimized tag SNP selection Annals of Human Genetics. 72: 834-847. PMID 18702637 DOI: 10.1111/J.1469-1809.2008.00469.X  0.704
2008 Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, Daly MJ, Eskin E. Efficient control of population structure in model organism association mapping. Genetics. 178: 1709-23. PMID 18385116 DOI: 10.1534/Genetics.107.080101  0.581
2008 Choi A, Zaitlen N, Han B, Pipatsrisawat K, Darwiche A, Eskin E. Efficient genome wide tagging by reduction to SAT Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5251: 135-147. DOI: 10.1007/978-3-540-87361-7_12  0.641
2007 Zaitlen N, Kang HM, Eskin E, Halperin E. Leveraging the HapMap correlation structure in association studies. American Journal of Human Genetics. 80: 683-91. PMID 17357074 DOI: 10.1086/513109  0.594
2007 O'Rourke S, Zaitlen N, Jojic N, Eskin E. Reconstructing the phylogeny of mobile elements Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4453: 196-210.  0.448
2005 Zaitlen NA, Kang HM, Feolo ML, Sherry ST, Halperin E, Eskin E. Inference and analysis of haplotypes from combined genotyping studies deposited in dbSNP. Genome Research. 15: 1594-600. PMID 16251470 DOI: 10.1101/Gr.4297805  0.555
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