| Year |
Citation |
Score |
| 2023 |
Ballard CJ, Paserba MR, Daniel EJP, Hurtado-Guerrero R, Gerken TA. GalNAc-T isozyme surface charge governs charge substrate preferences to modulate mucin type O-glycosylation. Glycobiology. PMID 37555669 DOI: 10.1093/glycob/cwad066 |
0.325 |
|
| 2020 |
Mohl JE, Gerken T, Leung MY. Predicting mucin-type O-Glycosylation using enhancement value products from derived protein features. Journal of Theoretical & Computational Chemistry. 19. PMID 33208985 DOI: 10.1142/S0219633620400039 |
0.422 |
|
| 2020 |
Mohl JE, Gerken TA, Leung MY. ISOGlyP: de novo prediction of isoform specific mucin-type O-glycosylation. Glycobiology. PMID 32681163 DOI: 10.1093/Glycob/Cwaa067 |
0.409 |
|
| 2020 |
May C, Ji S, Syed ZA, Revoredo L, Daniel EJP, Gerken TA, Tabak LA, Samara NL, Ten Hagen KG. Differential splicing of the lectin domain of an O-glycosyltransferase modulates both peptide and glycopeptide preferences. The Journal of Biological Chemistry. PMID 32669364 DOI: 10.1074/Jbc.Ra120.014700 |
0.435 |
|
| 2020 |
Daniel EJP, Las Rivas M, Lira-Navarrete E, García-García A, Hurtado-Guerrero R, Clausen H, Gerken TA. Ser and Thr Acceptor Preferences of the GalNAc-Ts Vary Among Isoenzymes to Modulate Mucin Type O-Glycosylation. Glycobiology. PMID 32304323 DOI: 10.1093/Glycob/Cwaa036 |
0.446 |
|
| 2019 |
Fernandez AJ, Daniel EJP, Mahajan SP, Gray JJ, Gerken TA, Tabak LA, Samara NL. The structure of the colorectal cancer-associated enzyme GalNAc-T12 reveals how nonconserved residues dictate its function. Proceedings of the National Academy of Sciences of the United States of America. PMID 31548401 DOI: 10.1073/Pnas.1902211116 |
0.412 |
|
| 2019 |
Salom D, Jin H, Gerken TA, Yu C, Huang L, Palczewski K. Human red and green cone opsins are O-glycosylated at an N-terminal Ser/Thr-rich domain conserved in vertebrates. The Journal of Biological Chemistry. PMID 30948514 DOI: 10.1074/Jbc.Ra118.006835 |
0.378 |
|
| 2019 |
Rivas Mdl, Lira-Navarrete E, Gerken TA, Hurtado-Guerrero R. Polypeptide GalNAc-Ts: from redundancy to specificity. Current Opinion in Structural Biology. 56: 87-96. PMID 30703750 DOI: 10.1016/J.Sbi.2018.12.007 |
0.409 |
|
| 2019 |
Rivas MdL, Daniel EJP, Narimatsu Y, Companon I, Kato K, Hermosilla P, Thureau A, Ceballos-Laita L, Coelho H, Bernado P, Marcelo F, Hansen L, Maeda R, Lostao A, Corzana F, ... ... Gerken TA, et al. Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3. Nature Chemical Biology. 16: 351-360. DOI: 10.2210/Pdb6S24/Pdb |
0.39 |
|
| 2018 |
de Las Rivas M, Paul Daniel EJ, Coelho H, Lira-Navarrete E, Raich L, Compañón I, Diniz A, Lagartera L, Jiménez-Barbero J, Clausen H, Rovira C, Marcelo F, Corzana F, Gerken TA, Hurtado-Guerrero R. Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4. Acs Central Science. 4: 1274-1290. PMID 30276263 DOI: 10.1021/Acscentsci.8B00488 |
0.407 |
|
| 2018 |
Sletmoen M, Gerken TA, Stokke BT, Burchell J, Brewer CF. Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate-carbohydrate interactions. Glycobiology. 28: 437-442. PMID 29618060 DOI: 10.1093/Glycob/Cwy032 |
0.346 |
|
| 2017 |
Rivas ML, Lira-Navarrete E, Daniel EJP, Compañón I, Coelho H, Diniz A, Jiménez-Barbero J, Peregrina JM, Clausen H, Corzana F, Marcelo F, Jiménez-Osés G, Gerken TA, Hurtado-Guerrero R. The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences. Nature Communications. 8: 1959. PMID 29208955 DOI: 10.1038/S41467-017-02006-0 |
0.434 |
|
| 2016 |
Festari MF, Trajtenberg F, Berois N, Pantano S, Revoredo L, Kong Y, Solari-Saquieres P, Narimatsu Y, Freire T, Bay S, Robello C, Bénard J, Gerken TA, Clausen H, Osinaga E. Revisiting the human polypeptide GalNAc-T1 and T13 paralogs. Glycobiology. PMID 27913570 DOI: 10.1093/Glycob/Cww111 |
0.396 |
|
| 2016 |
Haugstad KE, Hadjialirezaei S, Stokke BT, Brewer CF, Gerken TA, Burchell J, Picco G, Sletmoen M. Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions. Glycobiology. PMID 27282157 DOI: 10.1093/Glycob/Cww065 |
0.312 |
|
| 2016 |
Mohl J, Gerken T, Leung M. Constructing an iterative method for predicting protein O-glycosylation sites glycosylated by different GalNAc-transferase isoforms F1000research. 5. DOI: 10.7490/F1000Research.1112732.1 |
0.339 |
|
| 2015 |
Revoredo L, Wang S, Bennett EP, Clausen H, Moremen KW, Jarvis DL, Ten Hagen KG, Tabak LA, Gerken TA. Mucin Type O-Glycosylation is Controlled by Short and Long Range Glycopeptide Substrate Recognition that Varies Among Members of the Polypeptide GalNAc Transferase (ppGalNAc-T) Family. Glycobiology. PMID 26610890 DOI: 10.1093/Glycob/Cwv108 |
0.482 |
|
| 2015 |
Haugstad KE, Stokke BT, Brewer CF, Gerken TA, Sletmoen M. Single molecule study of heterotypic interactions between mucins possessing the Tn cancer antigen. Glycobiology. 25: 524-34. PMID 25527429 DOI: 10.1093/Glycob/Cwu183 |
0.356 |
|
| 2015 |
Kong Y, Joshi HJ, Schjoldager KT, Madsen TD, Gerken TA, Vester-Christensen MB, Wandall HH, Bennett EP, Levery SB, Vakhrushev SY, Clausen H. Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis. Glycobiology. 25: 55-65. PMID 25155433 DOI: 10.1093/Glycob/Cwu089 |
0.466 |
|
| 2013 |
Gerken TA, Revoredo L, Thome JJ, Tabak LA, Vester-Christensen MB, Clausen H, Gahlay GK, Jarvis DL, Johnson RW, Moniz HA, Moremen K. The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation. The Journal of Biological Chemistry. 288: 19900-14. PMID 23689369 DOI: 10.1074/Jbc.M113.477877 |
0.475 |
|
| 2012 |
Haugstad KE, Gerken TA, Stokke BT, Dam TK, Brewer CF, Sletmoen M. Enhanced self-association of mucins possessing the T and Tn carbohydrate cancer antigens at the single-molecule level. Biomacromolecules. 13: 1400-1409. PMID 22428527 DOI: 10.1021/Bm300135H |
0.319 |
|
| 2012 |
Gerken TA. O-glycoprotein biosynthesis: site localization by Edman degradation and site prediction based on random peptide substrates. Methods of Molecular Biology. 842: 81-108. PMID 22259131 DOI: 10.1007/978-1-61779-513-8_5 |
0.442 |
|
| 2012 |
Raman J, Guan Y, Perrine CL, Gerken TA, Tabak LA. UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. Glycobiology. 22: 768-77. PMID 22186971 DOI: 10.1093/Glycob/Cwr183 |
0.413 |
|
| 2012 |
Bennett EP, Mandel U, Clausen H, Gerken TA, Fritz TA, Tabak LA. Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family. Glycobiology. 22: 736-56. PMID 22183981 DOI: 10.1093/Glycob/Cwr182 |
0.396 |
|
| 2011 |
Gerken TA, Jamison O, Perrine CL, Collette JC, Moinova H, Ravi L, Markowitz SD, Shen W, Patel H, Tabak LA. Emerging paradigms for the initiation of mucin-type protein O-glycosylation by the polypeptide GalNAc transferase family of glycosyltransferases. The Journal of Biological Chemistry. 286: 14493-507. PMID 21349845 DOI: 10.1074/Jbc.M111.218701 |
0.475 |
|
| 2010 |
Miwa HE, Gerken TA, Jamison O, Tabak LA. Isoform-specific O-glycosylation of osteopontin and bone sialoprotein by polypeptide N-acetylgalactosaminyltransferase-1. The Journal of Biological Chemistry. 285: 1208-19. PMID 19880513 DOI: 10.1074/Jbc.M109.035436 |
0.426 |
|
| 2009 |
Perrine CL, Ganguli A, Wu P, Bertozzi CR, Fritz TA, Raman J, Tabak LA, Gerken TA. Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2. The Journal of Biological Chemistry. 284: 20387-97. PMID 19460755 DOI: 10.1074/Jbc.M109.017236 |
0.443 |
|
| 2009 |
Sletmoen M, Dam TK, Gerken TA, Stokke BT, Brewer CF. Single-molecule pair studies of the interactions of the α-GalNAc (Tn-antigen) form of porcine submaxillary mucin with soybean agglutinin Biopolymers. 91: 719-728. PMID 19384982 DOI: 10.1002/Bip.21213 |
0.369 |
|
| 2009 |
Dam TK, Gerken TA, Brewer CF. Thermodynamics of multivalent carbohydrate-lectin cross-linking interactions: importance of entropy in the bind and jump mechanism. Biochemistry. 48: 3822-3827. PMID 19292456 DOI: 10.1021/Bi9002919 |
0.367 |
|
| 2009 |
Miwa HE, Gerken TA, Huynh TD, Duesler LR, Cotter M, Hering TM. Conserved sequence in the aggrecan interglobular domain modulates cleavage by ADAMTS-4 and ADAMTS-5. Biochimica Et Biophysica Acta. 1790: 161-72. PMID 19101611 DOI: 10.1016/J.Bbagen.2008.11.008 |
0.338 |
|
| 2009 |
Perrine C, Ju T, Cummings RD, Gerken TA. Systematic determination of the peptide acceptor preferences for the human UDP-Gal:glycoprotein-alpha-GalNAc beta 3 galactosyltransferase (T-synthase). Glycobiology. 19: 321-8. PMID 19073881 DOI: 10.1093/Glycob/Cwn143 |
0.457 |
|
| 2008 |
Gerken TA, Hagen KGT, Jamison O. Conservation of peptide acceptor preferences between Drosophila and mammalian polypeptide-GalNAc transferase ortholog pairs. Glycobiology. 18: 861-870. PMID 18669915 DOI: 10.1093/Glycob/Cwn073 |
0.442 |
|
| 2008 |
Raman J, Fritz TA, Gerken TA, Jamison O, Live D, Liu M, Tabak LA. The catalytic and lectin domains of UDP-GalNAc:polypeptide alpha-N-Acetylgalactosaminyltransferase function in concert to direct glycosylation site selection. The Journal of Biological Chemistry. 283: 22942-51. PMID 18562306 DOI: 10.1074/Jbc.M803387200 |
0.365 |
|
| 2007 |
Dam TK, Gerken TA, Cavada BS, Nascimento KS, Moura TR, Brewer CF. Binding Studies of α-GalNAc-specific Lectins to the α-GalNAc (Tn-antigen) Form of Porcine Submaxillary Mucin and Its Smaller Fragments Journal of Biological Chemistry. 282: 28256-28263. PMID 17652089 DOI: 10.1074/Jbc.M704677200 |
0.407 |
|
| 2006 |
Gerken TA, Raman J, Fritz TA, Jamison O. Identification of common and unique peptide substrate preferences for the UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferases T1 and T2 derived from oriented random peptide substrates. The Journal of Biological Chemistry. 281: 32403-16. PMID 16912039 DOI: 10.1074/Jbc.M605149200 |
0.461 |
|
| 2006 |
Miwa HE, Gerken TA, Huynh TD, Flory DM, Hering TM. Mammalian expression of full-length bovine aggrecan and link protein: formation of recombinant proteoglycan aggregates and analysis of proteolytic cleavage by ADAMTS-4 and MMP-13. Biochimica Et Biophysica Acta. 1760: 472-86. PMID 16427204 DOI: 10.1016/J.Bbagen.2005.12.003 |
0.357 |
|
| 2004 |
Gerken TA, Tep C, Rarick J. Role of Peptide Sequence and Neighboring Residue Glycosylation on the Substrate Specificity of the Uridine 5'-Diphosphate−α-N-acetylgalactosamine:Polypeptide N-acetylgalactosaminyl Transferases T1 and T2: Kinetic Modeling of the Porcine and Canine Submaxillary Gland Mucin Tandem Repeats† Biochemistry. 43: 9888-9900. PMID 15274643 DOI: 10.1021/Bi049178E |
0.466 |
|
| 2004 |
Pratt MR, Hang HC, Ten Hagen KG, Rarick J, Gerken TA, Tabak LA, Bertozzi CR. Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chemistry & Biology. 11: 1009-16. PMID 15271359 DOI: 10.1016/J.Chembiol.2004.05.009 |
0.384 |
|
| 2004 |
Gerken TA. Kinetic modeling confirms the biosynthesis of mucin core 1 (beta-Gal(1-3) alpha-GalNAc-O-Ser/Thr) O-glycan structures are modulated by neighboring glycosylation effects. Biochemistry. 43: 4137-4142. PMID 15065856 DOI: 10.1021/Bi036306A |
0.436 |
|
| 2003 |
Ten Hagen KG, Tran DT, Gerken TA, Stein DS, Zhang Z. Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster. The Journal of Biological Chemistry. 278: 35039-48. PMID 12829714 DOI: 10.1074/Jbc.M303836200 |
0.354 |
|
| 2002 |
Gerken TA, Zhang J, Levine J, Elhammer Å. Mucin core O-glycosylation is modulated by neighboring residue glycosylation status. Kinetic modeling of the site-specific glycosylation of the apo-porcine submaxillary mucin tandem repeat by UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases T1 and T2. Journal of Biological Chemistry. 277: 49850-49862. PMID 12397077 DOI: 10.1074/Jbc.M205851200 |
0.468 |
|
| 2002 |
Gerken TA, Gilmore M, Zhang J. Determination of the site-specific oligosaccharide distribution of the O-glycans attached to the porcine submaxillary mucin tandem repeat: Further evidence for the modulation of O-glycan side chain structures by peptide sequence. Journal of Biological Chemistry. 277: 7736-7751. PMID 11777921 DOI: 10.1074/Jbc.M111690200 |
0.441 |
|
| 1998 |
Gerken TA, Owens CL, Pasumarthy M. Site-specific core 1 O-glycosylation pattern of the porcine submaxillary gland mucin tandem repeat. Evidence for the modulation of glycan length by peptide sequence Journal of Biological Chemistry. 273: 26580-26588. PMID 9756896 DOI: 10.1074/Jbc.273.41.26580 |
0.448 |
|
| 1997 |
Ziady AG, Perales JC, Ferkol T, Gerken T, Beegen H, Perlmutter DH, Davis PB. Gene transfer into hepatoma cell lines via the serpin enzyme complex receptor. The American Journal of Physiology. 273: G545-52. PMID 9277436 DOI: 10.1152/Ajpgi.1997.273.2.G545 |
0.31 |
|
| 1997 |
Gerken TA, Owens CL, Pasumarthy M. Determination of the site-specific O-glycosylation pattern of the porcine submaxillary mucin tandem repeat glycopeptide. Model proposed for the polypeptide:GalNAc transferase peptide binding site Journal of Biological Chemistry. 272: 9709-9719. PMID 9092502 DOI: 10.1074/Jbc.272.15.9709 |
0.451 |
|
| 1996 |
Yike I, Ye J, Zhang Y, Manavalan P, Gerken TA, Dearborn DG. A recombinant peptide model of the first nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator: comparison of wild-type and delta F508 mutant forms. Protein Science. 5: 89-97. PMID 8771200 DOI: 10.1002/Pro.5560050111 |
0.381 |
|
| 1993 |
Butenhof KJ, Gerken TA. Structure and dynamics of mucin-like glycopeptides. Examination of peptide chain expansion and peptide-carbohydrate interactions by stochastic dynamics simulations. Biochemistry. 32: 2650-2663. PMID 8448122 DOI: 10.1021/Bi00061A025 |
0.422 |
|
| 1992 |
Gerken TA, Gupta R, Jentoft N. A novel approach for chemically deglycosylating O-linked glycoproteins. The deglycosylation of submaxillary and respiratory mucins. Biochemistry. 31: 639-648. PMID 1310044 DOI: 10.1021/Bi00118A002 |
0.395 |
|
| 1989 |
Gerken TA, Butenhof KJ, Shogren R. Effects of glycosylation on the conformation and dynamics of O-linked glycoproteins: carbon-13 NMR studies of ovine submaxillary mucin Biochemistry. 28: 5536-5543. PMID 2775722 DOI: 10.1021/Bi00439A030 |
0.434 |
|
| 1989 |
Shogren R, Gerken TA, Jentoft N. Role of glycosylation on the conformation and chain dimensions of O-linked glycoproteins: light-scattering studies of ovine submaxillary mucin Biochemistry. 28: 5525-5536. PMID 2775721 DOI: 10.1021/Bi00439A029 |
0.413 |
|
| 1987 |
Gerken TA, Jentoft N. Structure and dynamics of porcine submaxillary mucin as determined by natural abundance carbon-13 NMR spectroscopy Biochemistry. 26: 4689-4699. PMID 3663619 DOI: 10.1021/Bi00389A015 |
0.377 |
|
| 1986 |
Gerken TA. The solution structure of mucous glycoproteins: Proton NMR studies of native and modified ovine submaxillary mucin Archives of Biochemistry and Biophysics. 247: 239-253. PMID 3013090 DOI: 10.1016/0003-9861(86)90581-3 |
0.39 |
|
| 1984 |
Gerken TA, Dearborn DG. Carbon-13 NMR studies of native and modified ovine submaxillary mucin. Biochemistry. 23: 1485-1497. PMID 6722102 DOI: 10.1021/Bi00302A023 |
0.337 |
|
| 1984 |
Gerken TA. Amino group environments and metal binding properties of carbon-13 reductively methylated bovine alpha-lactalbumin. Biochemistry. 23: 4688-4697. PMID 6437440 DOI: 10.1021/Bi00315A026 |
0.342 |
|
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