Year |
Citation |
Score |
2022 |
Blaha CS, Ramakrishnan G, Jeon SM, Nogueira V, Rho H, Kang S, Bhaskar P, Terry AR, Aissa AF, Frolov MV, Patra KC, Brooks Robey R, Hay N. A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis. Nature Communications. 13: 899. PMID 35173161 DOI: 10.1038/s41467-022-28440-3 |
0.72 |
|
2015 |
Yu WN, Nogueira V, Sobhakumari A, Patra KC, Bhaskar PT, Hay N. Systemic Akt1 Deletion after Tumor Onset in p53(-/-) Mice Increases Lifespan and Regresses Thymic Lymphoma Emulating p53 Restoration. Cell Reports. 12: 610-21. PMID 26190111 DOI: 10.1016/J.Celrep.2015.06.057 |
0.698 |
|
2013 |
Patra KC, Wang Q, Bhaskar PT, Miller L, Wang Z, Wheaton W, Chandel N, Laakso M, Muller WJ, Allen EL, Jha AK, Smolen GA, Clasquin MF, Robey RB, Hay N. Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer. Cancer Cell. 24: 213-28. PMID 23911236 DOI: 10.1016/J.Ccr.2013.06.014 |
0.591 |
|
2013 |
Patra K, Wang Q, Bhaskar P, Miller L, Wang Z, Wheaton W, Chandel N, Laakso M, Muller W, Allen E, Jha A, Smolen G, Clasquin M, Robey R, Hay N. Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer Cancer Cell. 24: 399. DOI: 10.1016/J.Ccr.2013.08.029 |
0.552 |
|
2010 |
Chen CC, Jeon SM, Bhaskar PT, Nogueira V, Sundararajan D, Tonic I, Park Y, Hay N. FoxOs inhibit mTORC1 and activate Akt by inducing the expression of Sestrin3 and Rictor. Developmental Cell. 18: 592-604. PMID 20412774 DOI: 10.1016/J.Devcel.2010.03.008 |
0.748 |
|
2009 |
Bhaskar PT, Nogueira V, Patra KC, Jeon SM, Park Y, Robey RB, Hay N. mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition. Molecular and Cellular Biology. 29: 5136-47. PMID 19620286 DOI: 10.1128/Mcb.01946-08 |
0.748 |
|
2007 |
Bhaskar PT, Hay N. The two TORCs and Akt. Developmental Cell. 12: 487-502. PMID 17419990 DOI: 10.1016/J.Devcel.2007.03.020 |
0.602 |
|
2006 |
Skeen JE, Bhaskar PT, Chen CC, Chen WS, Peng XD, Nogueira V, Hahn-Windgassen A, Kiyokawa H, Hay N. Akt deficiency impairs normal cell proliferation and suppresses oncogenesis in a p53-independent and mTORC1-dependent manner. Cancer Cell. 10: 269-80. PMID 17045205 DOI: 10.1016/J.Ccr.2006.08.022 |
0.718 |
|
2004 |
Majewski N, Nogueira V, Bhaskar P, Coy PE, Skeen JE, Gottlob K, Chandel NS, Thompson CB, Robey RB, Hay N. Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Molecular Cell. 16: 819-30. PMID 15574336 DOI: 10.1016/J.Molcel.2004.11.014 |
0.559 |
|
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