Nancy J. Philp - Publications

Affiliations: 
Cell and Developmental Biology Thomas Jefferson University, Philadelphia, PA, United States 
Area:
Cell Biology

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Han JYS, Kinoshita J, Bisetto S, Bell BA, Nowak RA, Peachey NS, Philp NJ. Role of monocarboxylate transporters in regulating metabolic homeostasis in the outer retina: Insight gained from cell-specific Bsg deletion. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32112484 DOI: 10.1096/Fj.201902961R  0.454
2020 Lakkaraju A, Umapathy A, Tan LX, Daniele L, Philp NJ, Boesze-Battaglia K, Williams DS. The Cell Biology of the Retinal Pigment Epithelium. Progress in Retinal and Eye Research. 100846. PMID 32105772 DOI: 10.1016/J.Preteyeres.2020.100846  0.379
2019 Silagi ES, Novais EJ, Bisetto S, Telonis AG, Snuggs J, Le Maitre CL, Qiu Y, Kurland IJ, Shapiro IM, Philp NJ, Risbud MV. Lactate Efflux from Intervertebral Disc Cells is Required for Maintenance of Spine Health. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31692093 DOI: 10.1002/Jbmr.3908  0.336
2019 Daniele LL, Caughey J, Volland S, Sharp RC, Dhingra A, Williams DS, Philp NJ, Boesze-Battaglia K. Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B. American Journal of Physiology. Cell Physiology. PMID 31577510 DOI: 10.1152/Ajpcell.00185.2019  0.354
2019 Grenell A, Wang Y, Yam M, Swarup A, Dilan TL, Hauer A, Linton JD, Philp NJ, Gregor E, Zhu S, Shi Q, Murphy J, Guan T, Lohner D, Kolandaivelu S, et al. Loss of MPC1 reprograms retinal metabolism to impair visual function. Proceedings of the National Academy of Sciences of the United States of America. 116: 3530-3535. PMID 30808746 DOI: 10.1073/Pnas.1812941116  0.344
2019 Léveillard T, Philp NJ, Sennlaub F. Is Retinal Metabolic Dysfunction at the Center of the Pathogenesis of Age-related Macular Degeneration? International Journal of Molecular Sciences. 20. PMID 30754662 DOI: 10.3390/Ijms20030762  0.387
2018 Swarup A, Samuels IS, Bell BA, Han JYS, Du J, Massenzio E, Abel ED, Boesze-Battaglia K, Peachey NS, Philp NJ. Modulating GLUT1 expression in the RPE decreases glucose levels in the retina: Impact on photoreceptors and Müller glial cells. American Journal of Physiology. Cell Physiology. PMID 30462537 DOI: 10.1152/Ajpcell.00410.2018  0.402
2018 Dhingra A, Bell BA, Peachey NS, Daniele LL, Reyes-Reveles J, Sharp RC, Jun B, Bazan NG, Sparrow JR, Kim HJ, Philp NJ, Boesze-Battaglia K. Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium. Frontiers in Cellular Neuroscience. 12: 351. PMID 30349463 DOI: 10.3389/Fncel.2018.00351  0.382
2018 Bisetto S, Whitaker-Menezes D, Wilski NA, Tuluc M, Curry J, Zhan T, Snyder CM, Martinez-Outschoorn UE, Philp NJ. Monocarboxylate Transporter 4 (MCT4) Knockout Mice Have Attenuated 4NQO Induced Carcinogenesis; A Role for MCT4 in Driving Oral Squamous Cell Cancer. Frontiers in Oncology. 8: 324. PMID 30211114 DOI: 10.3389/Fonc.2018.00324  0.326
2018 Peachey NS, Yu M, Han JYS, Lengacher S, Magistretti PJ, Pellerin L, Philp NJ. Impact of MCT1 Haploinsufficiency on the Mouse Retina. Advances in Experimental Medicine and Biology. 1074: 375-380. PMID 29721966 DOI: 10.1007/978-3-319-75402-4_46  0.448
2018 Swarup A, Bell BA, Du J, Han JYS, Soto J, Abel ED, Bravo-Nuevo A, FitzGerald PG, Peachey NS, Philp NJ. Deletion of GLUT1 in mouse lens epithelium leads to cataract formation. Experimental Eye Research. PMID 29604281 DOI: 10.1016/J.Exer.2018.03.021  0.352
2017 Wilde L, Roche M, Domingo-Vidal M, Tanson K, Philp N, Curry J, Martinez-Outschoorn U. Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development. Seminars in Oncology. 44: 198-203. PMID 29248131 DOI: 10.1053/J.Seminoncol.2017.10.004  0.334
2017 Reyes-Reveles J, Dhingra A, Alexander D, Bragin A, Philp NJ, Boesze-Battaglia K. Phagocytosis Dependent Ketogenesis in Retinal Pigment Epithelium. The Journal of Biological Chemistry. PMID 28302729 DOI: 10.1074/Jbc.M116.770784  0.361
2014 Lehmann GL, Benedicto I, Philp NJ, Rodriguez-Boulan E. Plasma membrane protein polarity and trafficking in RPE cells: past, present and future. Experimental Eye Research. 126: 5-15. PMID 25152359 DOI: 10.1016/J.Exer.2014.04.021  0.439
2014 Pfeffer BA, Philp NJ. Cell culture of retinal pigment epithelium: Special Issue. Experimental Eye Research. 126: 1-4. PMID 25152358 DOI: 10.1016/J.Exer.2014.07.010  0.314
2014 Adijanto J, Du J, Moffat C, Seifert EL, Hurley JB, Philp NJ. The retinal pigment epithelium utilizes fatty acids for ketogenesis implications for metabolic coupling with the outer retina Journal of Biological Chemistry. 289: 20570-20582. PMID 24898254 DOI: 10.1074/Jbc.M114.565457  0.383
2014 Adijanto J, Philp NJ. Cultured primary human fetal retinal pigment epithelium (hfRPE) as a model for evaluating RPE metabolism. Experimental Eye Research. 126: 77-84. PMID 24485945 DOI: 10.1016/J.Exer.2014.01.015  0.38
2013 Abplanalp J, Laczko E, Philp NJ, Neidhardt J, Zuercher J, Braun P, Schorderet DF, Munier FL, Verrey F, Berger W, Camargo SM, Kloeckener-Gruissem B. The cataract and glucosuria associated monocarboxylate transporter MCT12 is a new creatine transporter. Human Molecular Genetics. 22: 3218-26. PMID 23578822 DOI: 10.1093/Hmg/Ddt175  0.407
2012 Adijanto J, Philp NJ. The SLC16A family of monocarboxylate transporters (MCTs)--physiology and function in cellular metabolism, pH homeostasis, and fluid transport. Current Topics in Membranes. 70: 275-311. PMID 23177990 DOI: 10.1016/B978-0-12-394316-3.00009-0  0.41
2011 Castorino JJ, Gallagher-Colombo SM, Levin AV, Fitzgerald PG, Polishook J, Kloeckener-Gruissem B, Ostertag E, Philp NJ. Juvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane. Investigative Ophthalmology & Visual Science. 52: 6774-84. PMID 21778275 DOI: 10.1167/Iovs.10-6579  0.673
2011 Vogt SD, Curcio CA, Wang L, Li CM, McGwin G, Medeiros NE, Philp NJ, Kimble JA, Read RW. Retinal pigment epithelial expression of complement regulator CD46 is altered early in the course of geographic atrophy. Experimental Eye Research. 93: 413-23. PMID 21684273 DOI: 10.1016/J.Exer.2011.06.002  0.355
2011 Whitaker-Menezes D, Martinez-Outschoorn UE, Lin Z, Ertel A, Flomenberg N, Witkiewicz AK, Birbe RC, Howell A, Pavlides S, Gandara R, Pestell RG, Sotgia F, Philp NJ, Lisanti MP. Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts. Cell Cycle (Georgetown, Tex.). 10: 1772-83. PMID 21558814 DOI: 10.4161/Cc.10.11.15659  0.309
2011 Castorino JJ, Deborde S, Deora A, Schreiner R, Gallagher-Colombo SM, Rodriguez-Boulan E, Philp NJ. Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia. Traffic (Copenhagen, Denmark). 12: 483-98. PMID 21199217 DOI: 10.1111/J.1600-0854.2010.01155.X  0.699
2010 Schreiner R, Frindt G, Diaz F, Carvajal-Gonzalez JM, Perez Bay AE, Palmer LG, Marshansky V, Brown D, Philp NJ, Rodriguez-Boulan E. The absence of a clathrin adapter confers unique polarity essential to proximal tubule function. Kidney International. 78: 382-8. PMID 20531453 DOI: 10.1038/Ki.2010.166  0.362
2010 Gallagher-Colombo S, Maminishkis A, Tate S, Grunwald GB, Philp NJ. Modulation of MCT3 expression during wound healing of the retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 51: 5343-50. PMID 20505202 DOI: 10.1167/Iovs.09-5028  0.709
2009 Visser WE, Philp NJ, van Dijk TB, Klootwijk W, Friesema EC, Jansen J, Beesley PW, Ianculescu AG, Visser TJ. Evidence for a homodimeric structure of human monocarboxylate transporter 8. Endocrinology. 150: 5163-70. PMID 19797118 DOI: 10.1210/En.2009-0699  0.396
2009 Gallagher SM, Castorino JJ, Philp NJ. Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration. American Journal of Physiology. Cell Physiology. 296: C414-21. PMID 19073896 DOI: 10.1152/Ajpcell.00430.2008  0.375
2008 Daniele LL, Sauer B, Gallagher SM, Pugh EN, Philp NJ. Altered visual function in monocarboxylate transporter 3 (Slc16a8) knockout mice. American Journal of Physiology. Cell Physiology. 295: C451-7. PMID 18524945 DOI: 10.1152/Ajpcell.00124.2008  0.448
2007 Daniele LL, Adams RH, Durante DE, Pugh EN, Philp NJ. Novel distribution of junctional adhesion molecule-C in the neural retina and retinal pigment epithelium. The Journal of Comparative Neurology. 505: 166-76. PMID 17853450 DOI: 10.1002/Cne.21489  0.421
2007 Gallagher SM, Castorino JJ, Wang D, Philp NJ. Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231. Cancer Research. 67: 4182-9. PMID 17483329 DOI: 10.1158/0008-5472.Can-06-3184  0.37
2005 Deora AA, Philp N, Hu J, Bok D, Rodriguez-Boulan E. Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia. Proceedings of the National Academy of Sciences of the United States of America. 102: 16245-50. PMID 16260747 DOI: 10.1073/Pnas.0504419102  0.398
2005 Daniele LL, Lillo C, Lyubarsky AL, Nikonov SS, Philp N, Mears AJ, Swaroop A, Williams DS, Pugh EN. Cone-like morphological, molecular, and electrophysiological features of the photoreceptors of the Nrl knockout mouse. Investigative Ophthalmology & Visual Science. 46: 2156-67. PMID 15914637 DOI: 10.1167/Iovs.04-1427  0.307
2005 Zhang F, Vannucci SJ, Philp NJ, Simpson IA. Monocarboxylate transporter expression in the spontaneous hypertensive rat: effect of stroke. Journal of Neuroscience Research. 79: 139-45. PMID 15578721 DOI: 10.1002/Jnr.20312  0.359
2003 Fanelli A, Grollman EF, Wang D, Philp NJ. MCT1 and its accessory protein CD147 are differentially regulated by TSH in rat thyroid cells. American Journal of Physiology. Endocrinology and Metabolism. 285: E1223-9. PMID 14607782 DOI: 10.1152/Ajpendo.00172.2003  0.363
2003 Philp NJ, Wang D, Yoon H, Hjelmeland LM. Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells. Investigative Ophthalmology & Visual Science. 44: 1716-21. PMID 12657613 DOI: 10.1167/Iovs.02-0287  0.459
2003 Philp NJ, Ochrietor JD, Rudoy C, Muramatsu T, Linser PJ. Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse. Investigative Ophthalmology & Visual Science. 44: 1305-11. PMID 12601063 DOI: 10.1167/Iovs.02-0552  0.406
2001 Philp NJ, Yoon H, Lombardi L. Mouse MCT3 gene is expressed preferentially in retinal pigment and choroid plexus epithelia. American Journal of Physiology. Cell Physiology. 280: C1319-26. PMID 11287345 DOI: 10.1152/Ajpcell.2001.280.5.C1319  0.445
2000 Grollman EF, Philp NJ, McPhie P, Ward RD, Sauer B. Determination of transport kinetics of chick MCT3 monocarboxylate transporter from retinal pigment epithelium by expression in genetically modified yeast. Biochemistry. 39: 9351-7. PMID 10924129 DOI: 10.1021/Bi000464+  0.453
1999 Yoon H, Donoso LA, Philp NJ. Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2. Genomics. 60: 366-70. PMID 10493836 DOI: 10.1006/Geno.1999.5926  0.303
1999 Yoon H, Philp NJ. Genomic structure and developmental expression of the chicken nonocarboxylate transporter MCT3 gene. Experimental Eye Research. 67: 417-24. PMID 9820789 DOI: 10.1006/Exer.1998.0533  0.354
1998 Philp NJ, Yoon H, Grollman EF. Monocarboxylate transporter MCT1 is located in the apical membrane and MCT3 in the basal membrane of rat RPE. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 274: R1824-R1828. PMID 29586699 DOI: 10.1152/Ajpregu.1998.274.6.R1824  0.47
1998 Menko S, Philp N, Veneziale B, Walker J. Integrins and development: how might these receptors regulate differentiation of the lens. Annals of the New York Academy of Sciences. 842: 36-41. PMID 9599291 DOI: 10.1111/J.1749-6632.1998.Tb09629.X  0.354
1997 Yoon H, Fanelli A, Grollman EF, Philp NJ. Identification of a unique monocarboxylate transporter (MCT3) in retinal pigment epithelium. Biochemical and Biophysical Research Communications. 234: 90-4. PMID 9168967 DOI: 10.1006/Bbrc.1997.6588  0.46
1995 Philp N, Chu P, Pan TC, Zhang RZ, Chu ML, Stark K, Boettiger D, Yoon H, Kieber-Emmons T. Developmental expression and molecular cloning of REMP, a novel retinal epithelial membrane protein. Experimental Cell Research. 219: 64-73. PMID 7628551 DOI: 10.1006/Excr.1995.1205  0.455
1994 Huang JC, Mieziewska K, Philp N, van Veen T, Aguirre GD. Diethylene glycol distearate (DGD): a versatile embedding medium for retinal cytochemistry. Journal of Neuroscience Methods. 47: 227-34. PMID 8271821 DOI: 10.1016/0165-0270(93)90085-6  0.326
1994 Mieziewska K, Szél A, Van Veen T, Aguirre GD, Philp N. Redistribution of insoluble interphotoreceptor matrix components during photoreceptor differentiation in the mouse retina. The Journal of Comparative Neurology. 345: 115-24. PMID 8089273 DOI: 10.1002/Cne.903450109  0.305
1990 Philp NJ, Yoon MY, Hock RS. Identification and localization of talin in chick retinal pigment epithelial cells Experimental Eye Research. 51: 191-198. PMID 2117547 DOI: 10.1016/0014-4835(90)90072-3  0.412
1988 Philp NJ, Nachmias VT, Lee D, Stramm L, Buzdygon B. Is rhodopsin the ligand for receptor-mediated phagocytosis of rod outer segments by retinal pigment epithelium? Experimental Eye Research. 46: 21-8. PMID 2830126 DOI: 10.1016/S0014-4835(88)80089-7  0.364
1988 Philp NJ, Chang W, Long K. Light-stimulated protein movement in rod photoreceptor cells of the rat retina. Febs Letters. 225: 127-32. PMID 2826235 DOI: 10.1016/0014-5793(87)81144-4  0.325
1984 Weiss SJ, Philp NJ, Grollman EF. Iodide transport in a continuous line of cultured cells from rat thyroid. Endocrinology. 114: 1090-8. PMID 6705729 DOI: 10.1210/Endo-114-4-1090  0.366
1984 Weiss SJ, Philp NJ, Ambesi-Impiombato FS, Grollman EF. Thyrotropin-stimulated iodide transport mediated by adenosine 3',5'-monophosphate and dependent on protein synthesis. Endocrinology. 114: 1099-107. PMID 6323129 DOI: 10.1210/Endo-114-4-1099  0.319
1981 Philp NJ, Bernstein MH. Phagocytosis by retinal pigment epithelium explants in culture. Experimental Eye Research. 33: 47-53. PMID 7250231 DOI: 10.1016/S0014-4835(81)80080-2  0.331
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