Karen L. Edelblum, Ph.D. - Publications

Affiliations: 
2008 Vanderbilt University, Nashville, TN 
Area:
Cell Biology

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lei X, Ketelut-Carneiro N, Shmuel-Galia L, Xu W, Wilson R, Vierbuchen T, Chen Y, Reboldi A, Kang J, Edelblum KL, Ward D, Fitzgerald KA. Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules. The Journal of Experimental Medicine. 219. PMID 35792863 DOI: 10.1084/jem.20212563  0.3
2020 Fischer MA, Golovchenko NB, Edelblum KL. γδ T cell migration: Separating trafficking from surveillance behaviors at barrier surfaces. Immunological Reviews. PMID 32845516 DOI: 10.1111/Imr.12915  0.364
2019 Edelblum K, Gustafsson K, Pennington DJ, Willcox BE, Ribot JC. Bordeaux 2018: Wine, Cheese, and γδ T Cells. Frontiers in Immunology. 10: 2544. PMID 31708934 DOI: 10.3389/Fimmu.2019.02544  0.33
2019 Kuo WT, Shen L, Zuo L, Shashikanth N, Ong MLDM, Wu L, Zha J, Edelblum KL, Wang Y, Wang Y, Nilsen SP, Turner JR. Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression. Gastroenterology. PMID 31401143 DOI: 10.1053/J.Gastro.2019.07.058  0.323
2019 Jia L, Edelblum KL. Intravital Imaging of Intraepithelial Lymphocytes in Murine Small Intestine. Journal of Visualized Experiments : Jove. PMID 31282900 DOI: 10.3791/59853  0.4
2019 Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR. Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability. The Journal of Clinical Investigation. PMID 30667372 DOI: 10.1172/Jci98554  0.387
2019 Hu MD, Patterson AM, Kelly TJ, Watson A, Edelblum KL. 88 – A Novel Role for ΓH Intraepithelial Lymphocytes in the Regulation of Pathological Epithelial Cell Shedding Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)36822-2  0.377
2018 Hu MD, Ethridge AD, Lipstein R, Kumar S, Wang Y, Jabri B, Turner JR, Edelblum KL. Epithelial IL-15 Is a Critical Regulator of γδ Intraepithelial Lymphocyte Motility within the Intestinal Mucosa. Journal of Immunology (Baltimore, Md. : 1950). PMID 29884699 DOI: 10.4049/Jimmunol.1701603  0.34
2018 Pearce SC, Al-Jawadi A, Kishida K, Yu S, Hu M, Fritzky LF, Edelblum KL, Gao N, Ferraris RP. Marked differences in tight junction composition and macromolecular permeability among different intestinal cell types. Bmc Biology. 16: 19. PMID 29391007 DOI: 10.1186/S12915-018-0481-Z  0.362
2017 Hu MD, Edelblum KL. Sentinels at the frontline: the role of intraepithelial lymphocytes in inflammatory bowel disease. Current Pharmacology Reports. 3: 321-334. PMID 29242771 DOI: 10.1007/S40495-017-0105-2  0.377
2017 Edelblum KL, Sharon G, Singh G, Odenwald MA, Sailer A, Cao S, Ravens S, Thomsen I, El Bissati K, McLeod R, Dong C, Gurbuxani S, Prinz I, Mazmanian SK, Turner JR. The Microbiome Activates CD4 T-cell-mediated Immunity to Compensate for Increased Intestinal Permeability. Cellular and Molecular Gastroenterology and Hepatology. 4: 285-297. PMID 28795125 DOI: 10.1016/J.Jcmgh.2017.06.001  0.386
2017 Hu M, Ethridge AD, Jabri B, Edelblum KL. Epithelial Interleukin-15 Promotes Î"Î" T Cell Migration and Epithelial Surveillance Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)30453-5  0.38
2016 Edelblum KL. Dissecting the Requirement for Secondary Lymphoid Organs in Peripheral Regulatory T-Cell Development. Cellular and Molecular Gastroenterology and Hepatology. 2: 253-254. PMID 28174714 DOI: 10.1016/J.Jcmgh.2016.02.004  0.327
2015 Edelblum KL, Singh G, Odenwald MA, Lingaraju A, El Bissati K, McLeod R, Sperling AI, Turner JR. γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice. Gastroenterology. 148: 1417-26. PMID 25747597 DOI: 10.1053/J.Gastro.2015.02.053  0.417
2014 Nalle SC, Kwak HA, Edelblum KL, Joseph NE, Singh G, Khramtsova GF, Mortenson ED, Savage PA, Turner JR. Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease. Science Translational Medicine. 6: 243ra87. PMID 24990882 DOI: 10.1126/Scitranslmed.3008941  0.387
2012 Edelblum KL, Shen L, Weber CR, Marchiando AM, Clay BS, Wang Y, Prinz I, Malissen B, Sperling AI, Turner JR. Dynamic migration of γδ intraepithelial lymphocytes requires occludin. Proceedings of the National Academy of Sciences of the United States of America. 109: 7097-102. PMID 22511722 DOI: 10.1073/Pnas.1112519109  0.426
2011 Hobbs SS, Goettel JA, Liang D, Yan F, Edelblum KL, Frey MR, Mullane MT, Polk DB. TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G220-9. PMID 21566012 DOI: 10.1152/Ajpgi.00383.2010  0.502
2011 Marchiando AM, Shen L, Graham WV, Edelblum KL, Duckworth CA, Guan Y, Montrose MH, Turner JR, Watson AJ. The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology. 140: 1208-1218.e1-2. PMID 21237166 DOI: 10.1053/J.Gastro.2011.01.004  0.397
2011 Goettel JA, Liang D, Hilliard VC, Edelblum KL, Broadus MR, Gould KL, Hanks SK, Polk DB. KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1. Experimental Cell Research. 317: 452-63. PMID 21144847 DOI: 10.1016/J.Yexcr.2010.11.018  0.412
2011 Edelblum KL, Shen L, Marchiando AM, Wang Y, Sperling AI, Turner JR. Occludin Regulates γδ Intraepithelial Lymphocyte Migration In Vivo Gastroenterology. 140: S-132. DOI: 10.1016/S0016-5085(11)60540-4  0.331
2010 Edelblum KL, Marchiando AM, Shen L, Wang Y, Sperling AI, Turner JR. 578 Tight Junction Protein Expression by γδ IELs Regulates Gastrointestinal Lymphocyte-Epithelial Interactions Gastroenterology. 138: S-82. DOI: 10.1016/S0016-5085(10)60373-3  0.309
2009 Frey MR, Edelblum KL, Mullane MT, Liang D, Polk DB. The ErbB4 growth factor receptor is required for colon epithelial cell survival in the presence of TNF. Gastroenterology. 136: 217-26. PMID 18973758 DOI: 10.1053/J.Gastro.2008.09.023  0.452
2008 Edelblum KL, Goettel JA, Koyama T, McElroy SJ, Yan F, Polk DB. TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB. The Journal of Biological Chemistry. 283: 29485-94. PMID 18713739 DOI: 10.1074/Jbc.M801269200  0.432
2008 Edelblum KL, Washington MK, Koyama T, Robine S, Baccarini M, Polk DB. Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB. Gastroenterology. 135: 539-51. PMID 18598699 DOI: 10.1053/J.Gastro.2008.04.025  0.473
2008 McElroy SJ, Frey MR, Yan F, Edelblum KL, Goettel JA, John S, Polk DB. Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 295: G285-93. PMID 18467504 DOI: 10.1152/Ajpgi.00425.2007  0.52
2008 Frey MR, Edelblum KL, Liang D, Polk DB. T1846 ErbB-4 Promotes Intestinal Cell Survival in Response to Tumor Necrosis Factor Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)62687-6  0.365
2008 Edelblum KL, Washington MK, Polk DB. 914 Raf-1 Kinase Suppresses Inflammation-Associated Colon Carcinogenesis Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)60614-9  0.374
2006 Frey MR, Dise RS, Edelblum KL, Polk DB. p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration. The Embo Journal. 25: 5683-92. PMID 17139251 DOI: 10.1038/Sj.Emboj.7601457  0.54
2006 Edelblum KL, Yan F, Yamaoka T, Polk DB. Regulation of apoptosis during homeostasis and disease in the intestinal epithelium. Inflammatory Bowel Diseases. 12: 413-24. PMID 16670531 DOI: 10.1097/01.Mib.0000217334.30689.3E  0.381
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