Vaughn Smider - Publications

Affiliations: 
2006- Scripps Research Institute 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Altman PX, Parren M, Sang H, Ozorowski G, Lee WH, Smider VV, Wilson IA, Ward AB, Mwangi W, Burton DR, Sok D. HIV envelope trimers and gp120 as immunogens to induce broadly neutralizing antibodies in cows. Biorxiv : the Preprint Server For Biology. PMID 38585787 DOI: 10.1101/2024.03.20.585065  0.305
2023 Huang R, Warner Jenkins G, Kim Y, Stanfield RL, Singh A, Martinez-Yamout M, Kroon GJ, Torres JL, Jackson AM, Kelley A, Shaabani N, Zeng B, Bacica M, Chen W, Warner C, ... ... Smider VV, et al. The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303455120. PMID 37722054 DOI: 10.1073/pnas.2303455120  0.407
2021 Pekar L, Klewinghaus D, Arras P, Carrara SC, Harwardt J, Krah S, Yanakieva D, Toleikis L, Smider VV, Kolmar H, Zielonka S. Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity. Frontiers in Immunology. 12: 742418. PMID 34759924 DOI: 10.3389/fimmu.2021.742418  0.408
2018 Haakenson JK, Huang R, Smider VV. Diversity in the Cow Ultralong CDR H3 Antibody Repertoire. Frontiers in Immunology. 9: 1262. PMID 29915599 DOI: 10.3389/fimmu.2018.01262  0.453
2018 Stanfield RL, Haakenson J, Deiss TC, Criscitiello MF, Wilson IA, Smider VV. The Unusual Genetics and Biochemistry of Bovine Immunoglobulins. Advances in Immunology. 137: 135-164. PMID 29455846 DOI: 10.1016/Bs.Ai.2017.12.004  0.432
2017 Deiss TC, Vadnais M, Wang F, Chen PL, Torkamani A, Mwangi W, Lefranc MP, Criscitiello MF, Smider VV. Immunogenetic factors driving formation of ultralong VH CDR3 in Bos taurus antibodies. Cellular & Molecular Immunology. PMID 29200193 DOI: 10.1038/Cmi.2017.117  0.427
2017 Sok D, Le KM, Vadnais M, Saye-Francisco K, Jardine JG, Torres J, Berndsen ZT, Kong L, Stanfield R, Ruiz J, Ramos A, Liang CH, Chen PL, Criscitiello MF, Mwangi W, ... ... Smider VV, et al. Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows. Nature. PMID 28726771 DOI: 10.1038/Nature23301  0.402
2016 Stanfield RL, Wilson IA, Smider VV. Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Science Immunology. 1: aaf7962. PMID 28783675 DOI: 10.1126/sciimmunol.aaf7962  0.355
2016 Stanfield RL, Wilson IA, Smider VV. Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies. Science Immunology. 1. PMID 27574710 DOI: 10.1126/Sciimmunol.Aaf7962  0.302
2016 Vadnais ML, Smider VV. Bos taurus ultralong CDR H3 antibodies. Current Opinion in Structural Biology. 38: 62-67. PMID 27295423 DOI: 10.1016/j.sbi.2016.05.004  0.352
2016 Wold ED, Smider VV, Felding BH. Antibody Therapeutics in Oncology. Immunotherapy (Los Angeles, Calif.). 2. PMID 27081677  0.409
2016 Muyldermans S, Smider VV. Distinct antibody species: structural differences creating therapeutic opportunities. Current Opinion in Immunology. 40: 7-13. PMID 26922135 DOI: 10.1016/j.coi.2016.02.003  0.404
2015 Wold ED, Axup JY, Felding BH, Smider VV. Fc-Small Molecule Antibody Mimetics. Bioconjugate Chemistry. 26: 2311-4. PMID 26536496 DOI: 10.1021/Acs.Bioconjchem.5B00530  0.469
2015 de los Rios M, Criscitiello MF, Smider VV. Structural and genetic diversity in antibody repertoires from diverse species. Current Opinion in Structural Biology. 33: 27-41. PMID 26188469 DOI: 10.1016/J.Sbi.2015.06.002  0.379
2015 Hallam TJ, Wold E, Wahl A, Smider VV. Antibody conjugates with unnatural amino acids. Molecular Pharmaceutics. 12: 1848-62. PMID 25898256 DOI: 10.1021/acs.molpharmaceut.5b00082  0.454
2015 Wold ED, McBride R, Axup JY, Kazane SA, Smider VV. Antibody microarrays utilizing site-specific antibody-oligonucleotide conjugates. Bioconjugate Chemistry. 26: 807-11. PMID 25884500 DOI: 10.1021/Acs.Bioconjchem.5B00111  0.359
2014 Hallam TJ, Smider VV. Unnatural amino acids in novel antibody conjugates. Future Medicinal Chemistry. 6: 1309-24. PMID 25163001 DOI: 10.4155/fmc.14.79  0.423
2014 Furman JL, Kang M, Choi S, Cao Y, Wold ED, Sun SB, Smider VV, Schultz PG, Kim CH. A genetically encoded aza-Michael acceptor for covalent cross-linking of protein-receptor complexes. Journal of the American Chemical Society. 136: 8411-7. PMID 24846839 DOI: 10.1021/Ja502851H  0.505
2014 Grover RK, Zhu X, Nieusma T, Jones T, Boero I, MacLeod AS, Mark A, Niessen S, Kim HJ, Kong L, Assad-Garcia N, Kwon K, Chesi M, Smider VV, Salomon DR, et al. A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science (New York, N.Y.). 343: 656-61. PMID 24503852 DOI: 10.1126/Science.1246135  0.398
2014 Stanfield R, Smider V, Wilson I. Bovine antibodies with ultra long H3 Complementarity Determining Regions Acta Crystallographica Section a Foundations and Advances. 70: C255-C255. DOI: 10.1107/S2053273314097447  0.405
2013 Kularatne SA, Deshmukh V, Gymnopoulos M, Biroc SL, Xia J, Srinagesh S, Sun Y, Zou N, Shimazu M, Pinkstaff J, Ensari S, Knudsen N, Manibusan A, Axup JY, Kim CH, ... Smider VV, et al. Recruiting cytotoxic T cells to folate-receptor-positive cancer cells. Angewandte Chemie (International Ed. in English). 52: 12101-4. PMID 24573789 DOI: 10.1002/Anie.201306866  0.432
2013 Kim CH, Axup JY, Lawson BR, Yun H, Tardif V, Choi SH, Zhou Q, Dubrovska A, Biroc SL, Marsden R, Pinstaff J, Smider VV, Schultz PG. Bispecific small molecule-antibody conjugate targeting prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 110: 17796-801. PMID 24127589 DOI: 10.1073/Pnas.1316026110  0.513
2013 Zhang Y, Wang D, de Lichtervelde L, Sun SB, Smider VV, Schultz PG, Wang F. Functional antibody CDR3 fusion proteins with enhanced pharmacological properties. Angewandte Chemie (International Ed. in English). 52: 8295-8. PMID 23794517 DOI: 10.1002/Anie.201303656  0.586
2013 Wang F, Ekiert DC, Ahmad I, Yu W, Zhang Y, Bazirgan O, Torkamani A, Raudsepp T, Mwangi W, Criscitiello MF, Wilson IA, Schultz PG, Smider VV. Reshaping antibody diversity. Cell. 153: 1379-93. PMID 23746848 DOI: 10.1016/J.Cell.2013.04.049  0.517
2013 Day JW, Kim CH, Smider VV, Schultz PG. Identification of metal ion binding peptides containing unnatural amino acids by phage display. Bioorganic & Medicinal Chemistry Letters. 23: 2598-600. PMID 23541674 DOI: 10.1016/J.Bmcl.2013.02.106  0.411
2013 Bentley CA, Bazirgan OA, Graziano JJ, Holmes EM, Smider VV. Arrayed antibody library technology for therapeutic biologic discovery. Methods (San Diego, Calif.). 60: 91-8. PMID 23485577 DOI: 10.1016/J.Ymeth.2013.02.003  0.404
2013 Wang F, Sen S, Zhang Y, Ahmad I, Zhu X, Wilson IA, Smider VV, Magliery TJ, Schultz PG. Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation. Proceedings of the National Academy of Sciences of the United States of America. 110: 4261-6. PMID 23440204 DOI: 10.1073/Pnas.1301810110  0.527
2013 Kazane SA, Axup JY, Kim CH, Ciobanu M, Wold ED, Barluenga S, Hutchins BA, Schultz PG, Winssinger N, Smider VV. Self-assembled antibody multimers through peptide nucleic acid conjugation. Journal of the American Chemical Society. 135: 340-6. PMID 23210862 DOI: 10.1021/Ja309505C  0.571
2012 Axup JY, Bajjuri KM, Ritland M, Hutchins BM, Kim CH, Kazane SA, Halder R, Forsyth JS, Santidrian AF, Stafin K, Lu Y, Tran H, Seller AJ, Biroc SL, Szydlik A, ... ... Smider VV, et al. Synthesis of site-specific antibody-drug conjugates using unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 109: 16101-6. PMID 22988081 DOI: 10.1073/Pnas.1211023109  0.551
2012 Tsai C, Smider V, Hwang BJ, Chu G. Electrophoretic mobility shift assays for protein-DNA complexes involved in DNA repair. Methods in Molecular Biology (Clifton, N.J.). 920: 53-78. PMID 22941596 DOI: 10.1007/978-1-61779-998-3_5  0.35
2012 Kim CH, Axup JY, Dubrovska A, Kazane SA, Hutchins BA, Wold ED, Smider VV, Schultz PG. Synthesis of bispecific antibodies using genetically encoded unnatural amino acids. Journal of the American Chemical Society. 134: 9918-21. PMID 22642368 DOI: 10.1021/Ja303904E  0.544
2012 Mao H, Graziano J, Smider VV. Arrayed protein library technology for therapeutic biologic discovery Biotechnology and Genetic Engineering Reviews. 28: 131-145. PMID 22616485 DOI: 10.5661/Bger-28-131  0.373
2012 Kazane SA, Sok D, Cho EH, Uson ML, Kuhn P, Schultz PG, Smider VV. Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR. Proceedings of the National Academy of Sciences of the United States of America. 109: 3731-6. PMID 22345566 DOI: 10.1073/Pnas.1120682109  0.54
2011 Hutchins BM, Kazane SA, Staflin K, Forsyth JS, Felding-Habermann B, Smider VV, Schultz PG. Selective formation of covalent protein heterodimers with an unnatural amino acid. Chemistry & Biology. 18: 299-303. PMID 21439474 DOI: 10.1016/J.Chembiol.2011.01.006  0.578
2011 Hutchins BM, Kazane SA, Staflin K, Forsyth JS, Felding-Habermann B, Schultz PG, Smider VV. Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids. Journal of Molecular Biology. 406: 595-603. PMID 21237172 DOI: 10.1016/J.Jmb.2011.01.011  0.579
2010 Mao H, Graziano JJ, Chase TM, Bentley CA, Bazirgan OA, Reddy NP, Song BD, Smider VV. Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization. Nature Biotechnology. 28: 1195-202. PMID 20972421 DOI: 10.1038/Nbt.1694  0.411
2009 Sharma V, Heriot W, Trisler K, Smider V. A human germ line antibody light chain with hydrolytic properties associated with multimerization status. The Journal of Biological Chemistry. 284: 33079-87. PMID 19801545 DOI: 10.1074/Jbc.M109.036087  0.396
2009 Liu CC, Choe H, Farzan M, Smider VV, Schultz PG. Mutagenesis and evolution of sulfated antibodies using an expanded genetic code. Biochemistry. 48: 8891-8. PMID 19715291 DOI: 10.1021/Bi9011429  0.523
2009 Liu CC, Mack AV, Brustad EM, Mills JH, Groff D, Smider VV, Schultz PG. Evolution of proteins with genetically encoded "chemical warheads". Journal of the American Chemical Society. 131: 9616-7. PMID 19555063 DOI: 10.1021/Ja902985E  0.512
2009 Grünewald J, Hunt GS, Dong L, Niessen F, Wen BG, Tsao ML, Perera R, Kang M, Laffitte BA, Azarian S, Ruf W, Nasoff M, Lerner RA, Schultz PG, Smider VV. Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America. 106: 4337-42. PMID 19246393 DOI: 10.1073/Pnas.0900507106  0.52
2008 Liu CC, Mack AV, Tsao ML, Mills JH, Lee HS, Choe H, Farzan M, Schultz PG, Smider VV. Protein evolution with an expanded genetic code. Proceedings of the National Academy of Sciences of the United States of America. 105: 17688-93. PMID 19004806 DOI: 10.1073/Pnas.0809543105  0.565
2008 Grünewald J, Tsao ML, Perera R, Dong L, Niessen F, Wen BG, Kubitz DM, Smider VV, Ruf W, Nasoff M, Lerner RA, Schultz PG. Immunochemical termination of self-tolerance. Proceedings of the National Academy of Sciences of the United States of America. 105: 11276-80. PMID 18685087 DOI: 10.1073/Pnas.0804157105  0.534
2007 Trisler K, Looger LL, Sharma V, Baker M, Benson DE, Trauger S, Schultz PG, Smider VV. A metalloantibody that irreversibly binds a protein antigen. The Journal of Biological Chemistry. 282: 26344-53. PMID 17617633 DOI: 10.1074/Jbc.M704675200  0.564
2006 Leonard B, Sharma V, Smider V. Co-expression of antibody fab heavy and light chain genes from separate evolved compatible replicons in E. coli. Journal of Immunological Methods. 317: 56-63. PMID 17049550 DOI: 10.1016/J.Jim.2006.09.006  0.465
2006 Smider V, Hwang BJ, Chu G. Electrophoretic mobility shift assays to study protein binding to damaged DNA. Methods in Molecular Biology (Clifton, N.J.). 314: 323-44. PMID 16673891 DOI: 10.1385/1-59259-973-7:323  0.367
1997 Smider V, Chu G. The end-joining reaction in V(D)J recombination. Seminars in Immunology. 9: 189-97. PMID 9200330 DOI: 10.1006/Smim.1997.0070  0.333
1996 Errami A, Smider V, Rathmell WK, He DM, Hendrickson EA, Zdzienicka MZ, Chu G. Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants. Molecular and Cellular Biology. 16: 1519-26. PMID 8657125 DOI: 10.1128/Mcb.16.4.1519  0.357
1994 Smider V, Rathmell WK, Lieber MR, Chu G. Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science (New York, N.Y.). 266: 288-91. PMID 7939667 DOI: 10.1126/Science.7939667  0.354
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