| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2015 | Frankel AE, Woo JH, Ahn C, Foss FM, Duvic M, Neville PH, Neville DM. Resimmune, an anti-CD3ε recombinant immunotoxin, induces durable remissions in patients with cutaneous T-cell lymphoma. Haematologica. 100: 794-800. PMID 25795722 DOI: 10.3324/Haematol.2015.123711 | 0.373 | |||
| 2013 | Peraino JS, Schenk M, Zhang H, Li G, Hermanrud CE, Neville DM, Sachs DH, Huang CA, Duran-Struuck R, Wang Z. A truncated diphtheria toxin based recombinant porcine CTLA-4 fusion toxin. Journal of Immunological Methods. 391: 103-11. PMID 23470981 DOI: 10.1016/j.jim.2013.02.015 | 0.393 | |||
| 2013 | Zhang F, Shan L, Liu Y, Neville D, Woo JH, Chen Y, Korotcov A, Lin S, Huang S, Sridhar R, Liang W, Wang PC. An anti-PSMA bivalent immunotoxin exhibits specificity and efficacy for prostate cancer imaging and therapy. Advanced Healthcare Materials. 2: 736-44. PMID 23184611 DOI: 10.1002/Adhm.201200254 | 0.292 | |||
| 2011 | Wang Z, Duran-Struuck R, Crepeau R, Matar A, Hanekamp I, Srinivasan S, Neville DM, Sachs DH, Huang CA. Development of a diphtheria toxin based antiporcine CD3 recombinant immunotoxin. Bioconjugate Chemistry. 22: 2014-20. PMID 21866954 DOI: 10.1021/Bc200230H | 0.433 | |||
| 2010 | Woo JH, Lee YJ, Neville DM, Frankel AE. Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials Methods in Molecular Biology (Clifton, N.J.). 651: 157-175. PMID 20686966 DOI: 10.1007/978-1-60761-786-0_10 | 0.464 | |||
| 2009 | Frankel AE, Woo J, Zuckero SL, Mankin AA, Grable M, Mitchell K, Lee Y, Neville DM. CD3 immunotoxin therapy of cutaneous T cell lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e19511. PMID 27960968 DOI: 10.1200/jco.2009.27.15_suppl.e19511 | 0.44 | |||
| 2009 | Frankel AE, Zuckero SL, Mankin AA, Grable M, Mitchell K, Lee YJ, Neville DM, Woo JH. Anti-CD3 recombinant diphtheria immunotoxin therapy of cutaneous T cell lymphoma. Current Drug Targets. 10: 104-9. PMID 19199905 DOI: 10.2174/138945009787354539 | 0.44 | |||
| 2008 | Thomas JM, Contreras JL, Wang PX, Eckhoff DE, Asiedu C, Hubbard WJ, Cartner S, Thomas FT, Robbin ML, Nadler S, Cook WJ, Sharff J, Neville DM, Shiloach J. Retraction: Peritransplant tolerance induction with anti-CD3-immunotoxin: a matter of proinflammatory cytokine control. Transplantation. 85: 920. PMID 18360278 DOI: 10.1097/TP.0b013e318172dbe0 | 0.321 | |||
| 2008 | Woo JH, Bour SH, Dang T, Lee YJ, Park SK, Andreas E, Kang SH, Liu JS, Neville DM, Frankel AE. Preclinical studies in rats and squirrel monkeys for safety evaluation of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1). Cancer Immunology, Immunotherapy : Cii. 57: 1225-39. PMID 18256829 DOI: 10.1007/s00262-008-0457-x | 0.433 | |||
| 2008 | Woo JH, Liu JS, Kang SH, Singh R, Park SK, Su Y, Ortiz J, Neville DM, Willingham MC, Frankel AE. GMP production and characterization of the bivalent anti-human T cell immunotoxin, A-dmDT390-bisFv(UCHT1) for phase I/II clinical trials Protein Expression and Purification. 58: 1-11. PMID 18160309 DOI: 10.1016/j.pep.2007.11.006 | 0.374 | |||
| 2007 | Kim GB, Wang Z, Liu YY, Stavrou S, Mathias A, Goodwin KJ, Thomas JM, Neville DM. A fold-back single-chain diabody format enhances the bioactivity of an anti-monkey CD3 recombinant diphtheria toxin-based immunotoxin. Protein Engineering, Design & Selection : Peds. 20: 425-32. PMID 17693455 DOI: 10.1093/protein/gzm040 | 0.418 | |||
| 2007 | Wang Z, Kim GB, Woo JH, Liu YY, Mathias A, Stavrou S, Neville DM. Improvement of a recombinant anti-monkey anti-CD3 diphtheria toxin based immunotoxin by yeast display affinity maturation of the scFv. Bioconjugate Chemistry. 18: 947-55. PMID 17352456 DOI: 10.1021/bc0603438 | 0.415 | |||
| 2007 | Liu YY, Wang Z, Thomas J, Goodwin KJ, Stavrou S, Neville DM. Polymorphisms of CD3epsilon in cynomolgus and rhesus monkeys and their relevance to anti-CD3 antibodies and immunotoxins. Immunology and Cell Biology. 85: 357-62. PMID 17325695 DOI: 10.1038/sj.icb.7100042 | 0.412 | |||
| 2006 | Thomas JM, Eckhoff DE, Contreras JL, Thomas FT, Neville DM, Lobashevsky A, Hubbard WJ, Cook WJ. Retraction: Durable donor-specific T and B cell tolerance in rhesus macaques induced with peritransplantation anti-CD3 immunotoxin and deoxyspergualin: absence of chronic allograft nephropathy. Transplantation. 82: 577. PMID 16926605 DOI: 10.1097/01.tp.0000239527.00075.60 | 0.45 | |||
| 2006 | Cina RA, Wikiel KJ, Lee PW, Cameron AM, Hettiarachy S, Rowland H, Goodrich J, Colby C, Spitzer TR, Neville DM, Huang CA. Stable multilineage chimerism without graft versus host disease following nonmyeloablative haploidentical hematopoietic cell transplantation. Transplantation. 81: 1677-85. PMID 16794534 DOI: 10.1097/01.tp.0000226061.59196.84 | 0.366 | |||
| 2006 | Woo JH, Liu YY, Neville DM. Minimization of aggregation of secreted bivalent anti-human T cell immunotoxin in Pichia pastoris bioreactor culture by optimizing culture conditions for protein secretion Journal of Biotechnology. 121: 75-85. PMID 16107287 DOI: 10.1016/j.jbiotec.2005.07.004 | 0.274 | |||
| 2005 | Asiedu CK, Goodwin KJ, Balgansuren G, Jenkins SM, Le Bas-Bernardet S, Jargal U, Neville DM, Thomas JM. Elevated T regulatory cells in long-term stable transplant tolerance in rhesus macaques induced by anti-CD3 immunotoxin and deoxyspergualin. Journal of Immunology (Baltimore, Md. : 1950). 175: 8060-8. PMID 16339543 | 0.358 | |||
| 2005 | Liu YY, Woo JH, Neville DM. Overexpression of an anti-CD3 immunotoxin increases expression and secretion of molecular chaperone BiP/Kar2p by Pichia pastoris Applied and Environmental Microbiology. 71: 5332-5340. PMID 16151122 DOI: 10.1128/AEM.71.9.5332-5340.2005 | 0.301 | |||
| 2004 | Woo JH, Liu YY, Stavrou S, Neville DM. Increasing secretion of a bivalent anti-T-cell immunotoxin by Pichia pastoris Applied and Environmental Microbiology. 70: 3370-3376. PMID 15184133 DOI: 10.1128/AEM.70.6.3370-3376.2004 | 0.357 | |||
| 2004 | Hutchings A, Wu J, Asiedu C, Hubbard W, Eckhoff D, Contreras J, Thomas FT, Neville D, Thomas JM. The immune decision toward allograft tolerance in non-human primates requires early inhibition of innate immunity and induction of immune regulation. Transplant Immunology. 11: 335-44. PMID 12967786 DOI: 10.1016/S0966-3274(03)00054-6 | 0.313 | |||
| 2003 | Woo JH, Neville DM. Separation of bivalent anti-T cell immunotoxin from Pichia pastoris glycoproteins by borate anion exchange Biotechniques. 35: 392-398. PMID 12951782 | 0.321 | |||
| 2003 | Frankel AE, Neville DM, Bugge TA, Kreitman RJ, Leppla SH. Immunotoxin therapy of hematologic malignancies. Seminars in Oncology. 30: 545-57. PMID 12939723 DOI: 10.1016/S0093-7754(03)00241-0 | 0.392 | |||
| 2003 | Liu YY, Woo JH, Neville DM. Targeted introduction of a diphtheria toxin resistant mutation into the chromosomal EF-2 locus of Pichia gastoris and expression of immunotoxin in the EF-2 mutants Protein Expression and Purification. 30: 262-274. PMID 12880776 DOI: 10.1016/S1046-5928(03)00129-3 | 0.269 | |||
| 2002 | Woo JH, Liu YY, Mathias A, Stavrou S, Wang Z, Thompson J, Neville DM. Gene optimization is necessary to express a bivalent anti-human anti-T cell immunotoxin in Pichia pastoris. Protein Expression and Purification. 25: 270-82. PMID 12135560 DOI: 10.1016/S1046-5928(02)00009-8 | 0.367 | |||
| 2002 | Weetall M, Digan ME, Hugo R, Mathew S, Hopf C, Tart-Risher N, Zhang J, Shi V, Fu F, Hammond-McKibben D, West S, Brack R, Brinkmann V, Bergman R, Neville D, et al. T-cell depletion and graft survival induced by anti-human CD3 immunotoxins in human CD3epsilon transgenic mice. Transplantation. 73: 1658-66. PMID 12042656 DOI: 10.1097/00007890-200205270-00023 | 0.45 | |||
| 2001 | Thompson J, Stavrou S, Weetall M, Hexham JM, Digan ME, Wang Z, Woo JH, Yu Y, Mathias A, Liu YY, Ma S, Gordienko I, Lake P, Neville DM. Improved binding of a bivalent single-chain immunotoxin results in increased efficacy for in vivo T-cell depletion. Protein Engineering. 14: 1035-41. PMID 11809934 DOI: 10.1093/PROTEIN/14.12.1035 | 0.442 | |||
| 2001 | Hexham JM, Dudas D, Hugo R, Thompson J, King V, Dowling C, Neville DM, Digan ME, Lake P. Influence of relative binding affinity on efficacy in a panel of anti-CD3 scFv immunotoxins. Molecular Immunology. 38: 397-408. PMID 11684296 DOI: 10.1016/S0161-5890(01)00070-0 | 0.405 | |||
| 2001 | Fechner JH, Dong Y, Hong X, Brunner KG, Tsuchida M, Neville D, Scharff J, Lee F, Oberley TD, Peters D, Schultz JM, Manthei ER, Hamawy MM, Knechtle SJ. Graft survival in a rhesus renal transplant model after immunotoxin-mediated T-cell depletion is enhanced by mycophenolate and steroids. Transplantation. 72: 581-7. PMID 11544415 DOI: 10.1097/00007890-200108270-00005 | 0.499 | |||
| 2001 | Thomas JM, Contreras JL, Smyth CA, Lobashevsky A, Jenkins S, Hubbard WJ, Eckhoff DE, Stavrou S, Neville DM, Thomas FT. Successful reversal of streptozotocin-induced diabetes with stable allogeneic islet function in a preclinical model of type 1 diabetes. Diabetes. 50: 1227-36. PMID 11375321 DOI: 10.2337/DIABETES.50.6.1227 | 0.39 | |||
| 2001 | Hubbard WJ, Moore JK, Contreras JL, Smyth CA, Chen ZW, Lobashevsky AL, Nagata K, Neville DM, Thomas JM. Phenotypic and functional analysis of T-cell recovery after anti-CD3 immunotoxin treatment for tolerance induction in rhesus macaques. Human Immunology. 62: 479-87. PMID 11334671 DOI: 10.1016/S0198-8859(01)00235-X | 0.475 | |||
| 2000 | Thomas JM, Eckhoff DE, Contreras JL, Lobashevsky AL, Hubbard WJ, Moore JK, Cook WJ, Thomas FT, Neville DM. Durable donor-specific T and B cell tolerance in rhesus macaques induced with peritransplantation anti-CD3 immunotoxin and deoxyspergualin: absence of chronic allograft nephropathy. Transplantation. 69: 2497-503. PMID 10910269 | 0.413 | |||
| 2000 | Liu YY, Gordienko I, Mathias A, Ma S, Thompson J, Woo JH, Neville DM. Expression of an anti-CD3 single-chain immunotoxin with a truncated diphtheria toxin in a mutant CHO cell line. Protein Expression and Purification. 19: 304-11. PMID 10873546 DOI: 10.1006/PREP.2000.1255 | 0.354 | |||
| 2000 | Contreras JL, Eckhoff DE, Cartner S, Bilbao G, Ricordi C, Neville DM, Thomas FT, Thomas JM. Long-term functional islet mass and metabolic function after xenoislet transplantation in primates. Transplantation. 69: 195-201. PMID 10670626 DOI: 10.1097/00007890-200001270-00001 | 0.293 | |||
| 2000 | Huang CA, Fuchimoto Y, Scheier-Dolberg R, Murphy MC, Neville DM, Sachs DH. Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model. The Journal of Clinical Investigation. 105: 173-81. PMID 10642595 DOI: 10.1172/JCI7913 | 0.417 | |||
| 2000 | Hubbard WJ, Contreras JL, Eckhoff DE, Thomas FT, Neville DM, Thomas JM. Immunotoxins and tolerance induction in primates Current Opinion in Organ Transplantation. 5: 29-34. DOI: 10.1097/00075200-200003000-00006 | 0.281 | |||
| 2000 | Contreras JL, Eckhoff DE, Smyth CA, Hubbard WJ, Lobashevsky A, Thomas FT, Neville DM, Thomas JM. LONG-TERM ISLET ALLOGRAFT SURVIVAL IN STZ-INDUCED DIABETIC NONHUMAN PRIMATES TREATED WITH ONLY PERITRANSPLANT F(ab)2-IMMUNOTOXIN AND DEOXYSPERGUALIN (DSG). Transplantation. 69: S417. DOI: 10.1097/00007890-200004271-01167 | 0.255 | |||
| 2000 | Eckhoff DE, Contreras JL, Lobashevsky AL, Hubbard WJ, Moore J, Cook WJ, Zinn K, Thomas FT, Neville D, Thomas JM. A PRECLINCIAL PARADIGM OF TOLERANCE WITHOUT CHRONIC ALLOGRAFT NEPHROPATHY (CAN) FOLLOWING PERITRANSPLANT T CELL ABLATION (TCA) WITH DENDRITIC CELL MATURATION ARREST (DCMA). Transplantation. 69: S147. DOI: 10.1097/00007890-200004271-00132 | 0.391 | |||
| 2000 | Thomas JM, Ma S, Contreras JL, Hubbard WJ, Smyth CA, Thomas FT, Neville DM. CONTRASTING IN VITRO AND IN VIVO ACTIVITY OF F(AB)2 AND IGG ANTI-CD3 IMMUNOTOXIN (IT) IN TOLERANCE INDUCTION. Transplantation. 69: S124. DOI: 10.1097/00007890-200004271-00050 | 0.346 | |||
| 1999 | Thomas JM, Contreras JL, Jiang XL, Eckhoff DE, Wang PX, Hubbard WJ, Lobashevsky AL, Wang W, Asiedu C, Stavrou S, Cook WJ, Robbin ML, Thomas FT, Neville DM. Peritransplant tolerance induction in macaques: early events reflecting the unique synergy between immunotoxin and deoxyspergualin. Transplantation. 68: 1660-73. PMID 10609942 DOI: 10.1097/00007890-199912150-00009 | 0.391 | |||
| 1999 | Huang CA, Yamada K, Murphy MC, Shimizu A, Colvin RB, Neville DM, Sachs DH. In vivo T cell depletion in miniature swine using the swine CD3 immunotoxin, pCD3-CRM9. Transplantation. 68: 855-60. PMID 10515387 DOI: 10.1097/00007890-199909270-00019 | 0.463 | |||
| 1999 | Contreras JL, Eckhoff DE, Cartner S, Frenette L, Thomas FT, Robbin ML, Neville DM, Thomas JM. Tolerability and side effects of anti-CD3-immunotoxin in preclinical testing in kidney and pancreatic islet transplant recipients. Transplantation. 68: 215-9. PMID 10440390 DOI: 10.1097/00007890-199907270-00009 | 0.384 | |||
| 1999 | Thomas FT, Ricordi C, Contreras JL, Hubbard WJ, Jiang XL, Eckhoff DE, Cartner S, Bilbao G, Neville DM, Thomas JM. Reversal of naturally occuring diabetes in primates by unmodified islet xenografts without chronic immunosuppression. Transplantation. 67: 846-54. PMID 10199733 DOI: 10.1097/00007890-199903270-00011 | 0.356 | |||
| 1999 | Contreras J, Thomas F, Eckhoff E, Neville D, Thomas J. Long-Term Stable Islet Function In Primates With Xenoislet Transplant Tolerance Off Suppression Transplantation. 67. DOI: 10.1097/00007890-199905150-00094 | 0.313 | |||
| 1999 | Eckhoff DE, Moore J, Hubbard WJ, Contreras JI, Thomas FT, Neville DM, Thomas JM. SYNERGY OF 15-DEOXYSPERGUALIN WITH ANTICD3 IMMUNOTOXIN IN TOLERANCE INDUCTION IN RHESUS MONKEYS Transplantation. 67: S557. DOI: 10.1097/00007890-199905150-00085 | 0.264 | |||
| 1999 | Knechtle SJ, Fechner JH, Dong Y, Hong X, Tsuchida M, Brunner K, Neville D, Hamawy M. Central Tolerance Is Nota Significant Mechanism For Prolonged Allograft Survival In Anti-Cd3 Immunotoxin Treated Monkeys Transplantation. 67. DOI: 10.1097/00007890-199905150-00084 | 0.446 | |||
| 1999 | Wu A, Yamada K, Awwad M, Shimizu A, Watts A, Gojo S, Neville D, Cooper DK, Sykes M, Sachs DH. PROLONGED XENOGENEIC SKIN GRAFT SURVIVAL AFTER XENOGENEIC PORCINE THYMIC TRANSPLANTATION IN A NON-HUMAN PRIMATE MODEL Transplantation. 67: S259. DOI: 10.1097/00007890-199904150-01035 | 0.323 | |||
| 1999 | Hubbard WJ, Ma S, Neville DM, Contreras J, Wang B, Moore J, Thomas JM. COMPARISON OF ANTI-CD3∊ IMMUNOTOXIN CONSTRUCTED WITH EITHER JNTACT MAB OR F(AB)2 FOR TOLERANCE INDUCTION IN A RHESUS TRANSPLANT MODEL Transplantation. 67: S226. DOI: 10.1097/00007890-199904150-00901 | 0.361 | |||
| 1999 | Thomas J, Jiang X, Wang W, Contreras J, Eckhoff D, Hubbard W, Thomas F, Neville D. Transient Arrest Of Dendritic Cell Maturation: A Window Of Opportunity For Primate Tolerance Induction? Transplantation. 67. DOI: 10.1097/00007890-199904150-00837 | 0.318 | |||
| 1999 | Knechtle S, Fechner J, Dong Y, Hong X, Tsuchida M, Neville D, Hamawy M. T Cell Loss And Recovery Is A Predictor Of Allograft Survival In Anti-Cd3 Immunotoxin Treated Monkeys Transplantation. 67. DOI: 10.1097/00007890-199904150-00142 | 0.496 | |||
| 1998 | Jonker M, Slingerland W, Ossevoort M, Kuhn E, Neville D, Friend P, Calne R. Induction of kidney graft acceptance by creating a window of opportunity for immunologic engagement (WOFIE) in rhesus monkeys Transplantation Proceedings. 30: 2441-2443. PMID 9723530 DOI: 10.1016/S0041-1345(98)00679-4 | 0.309 | |||
| 1998 | Knechtle SJ, Fechner JH, Stavrou S, Neville DM, Dong Y, Hong X, Tsuchida M, Hamawy MM. Reversal of acute allograft rejection using immunotoxin Transplantation Proceedings. 30: 2150-2151. PMID 9723422 DOI: 10.1016/S0041-1345(98)00569-7 | 0.289 | |||
| 1998 | Armstrong N, Buckley P, Oberley T, Fechner J, Dong Y, Hong X, Kirk A, Neville D, Knechtle S. Analysis of primate renal allografts after T-cell depletion with anti-CD3-CRM9. Transplantation. 66: 5-13. PMID 9679815 DOI: 10.1097/00007890-199807150-00002 | 0.463 | |||
| 1998 | Contreras JL, Wang PX, Eckhoff DE, Lobashevsky AL, Asiedu C, Frenette L, Robbin ML, Hubbard WJ, Cartner S, Nadler S, Cook WJ, Sharff J, Shiloach J, Thomas FT, Neville DM, et al. Peritransplant tolerance induction with anti-CD3-immunotoxin: a matter of proinflammatory cytokine control. Transplantation. 65: 1159-69. PMID 9603161 | 0.408 | |||
| 1998 | Wu A, Esnaola NF, Yamada K, Awwad M, Shimizu A, Huang C, Wain J, Zhao Y, Neville D, Cooper DK, Sykes M, Sachs DH. XENOGENEIC THYMIC TRANSPLANTATION IN A PIG-TO-NON-HUMAN-PRIMATE MODEL Transplantation. 65: 194. DOI: 10.1097/00007890-199805131-00462 | 0.324 | |||
| 1998 | Contreras J, Eckhoff D, Cartner S, Frenette L, Thomas F, Robbins M, Neville D, Thomas J. Tolerability and Side Effects of Anti-CD3 Immunotoxin (αCD3-IT) in Preclinical Testing in Kidney Allograft Recipients Transplantation. 65: 159. DOI: 10.1097/00007890-199805131-00320 | 0.373 | |||
| 1997 | Ma S, Hu H, Thompson J, Stavrou S, Scharff J, Neville DM. Genetic construction and characterization of an anti-monkey CD3 single-chain immunotoxin with a truncated diphtheria toxin Bioconjugate Chemistry. 8: 695-701. PMID 9327133 DOI: 10.1021/bc9701398 | 0.441 | |||
| 1997 | Thomas JM, Neville DM, Contreras JL, Eckhoff DE, Meng G, Lobashevsky AL, Wang PX, Huang ZQ, Verbanac KM, Haisch CE, Thomas FT. Preclinical studies of allograft tolerance in rhesus monkeys: a novel anti-CD3-immunotoxin given peritransplant with donor bone marrow induces operational tolerance to kidney allografts. Transplantation. 64: 124-35. PMID 9233712 DOI: 10.1097/00007890-199707150-00022 | 0.488 | |||
| 1997 | Fechner JH, Vargo DJ, Geissler EK, Graeb C, Wang J, Hanaway MJ, Watkins DI, Piekarczyk M, Neville DM, Knechtle SJ. Split tolerance induced by immunotoxin in a rhesus kidney allograft model. Transplantation. 63: 1339-45. PMID 9158030 DOI: 10.1097/00007890-199705150-00023 | 0.376 | |||
| 1997 | Hu H, Stavrou S, Cairns Baker B, Tornatore C, Scharff J, Okunieff P, Neville DM. Depletion of T lymphocytes with immunotoxin retards the progress of experimental allergic encephalomyelitis in rhesus monkeys Cellular Immunology. 177: 26-34. PMID 9140093 DOI: 10.1006/cimm.1997.1096 | 0.425 | |||
| 1997 | Fechner JH, Vargo DJ, Geissler EK, Wang J, Neville DM, Knechtle SJ. Mechanisms of tolerance induced by an immunotoxin against CD3 epsilon in a rhesus kidney allograft model. Transplantation Proceedings. 29: 1158. PMID 9123249 DOI: 10.1016/S0041-1345(96)00503-9 | 0.326 | |||
| 1997 | Knechtle SJ, Vargo D, Fechner J, Zhai Y, Wang J, Hanaway MJ, Scharff J, Hu H, Knapp L, Watkins D, Neville DM. FN18-CRM9 immunotoxin promotes tolerance in primate renal allografts. Transplantation. 63: 1-6. PMID 9000652 DOI: 10.1097/00007890-199701150-00002 | 0.439 | |||
| 1996 | Neville DM, Scharff J, Hu HZ, Rigaut K, Shiloach J, Slingerland W, Jonker M. A new reagent for the induction of T-cell depletion, anti-CD3-CRM9. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 19: 85-92. PMID 8732691 DOI: 10.1097/00002371-199603000-00001 | 0.45 | |||
| 1995 | Rigaut KD, Scharff JE, Neville DM. Selective killing of T cells by immunotoxins directed at distinct V beta epitopes of the T cell receptor. European Journal of Immunology. 25: 2077-82. PMID 7542605 DOI: 10.1002/eji.1830250741 | 0.39 | |||
| 1995 | Thompson J, Hu H, Scharff J, Neville DM. An anti-CD3 single-chain immunotoxin with a truncated diphtheria toxin avoids inhibition by pre-existing antibodies in human blood. The Journal of Biological Chemistry. 270: 28037-41. PMID 7499288 DOI: 10.1074/jbc.270.47.28037 | 0.415 | |||
| 1992 | Neville DM, Scharff J, Srinivasachar K. In vivo T-cell ablation by a holo-immunotoxin directed at human CD3. Proceedings of the National Academy of Sciences of the United States of America. 89: 2585-9. PMID 1372981 DOI: 10.1073/pnas.89.7.2585 | 0.441 | |||
| 1990 | Neville DM, Marsh JW. Methods for quantifying immunotoxin efficacy. Cancer Treatment and Research. 37: 393-404. PMID 2908635 DOI: 10.1007/978-1-4613-1083-9_21 | 0.2 | |||
| 1990 | Hudson TH, Neville DM. Enhancement of immunotoxin action: manipulation of the cellular routing of proteins. Cancer Treatment and Research. 37: 371-89. PMID 2908633 DOI: 10.1007/978-1-4613-1083-9_20 | 0.233 | |||
| 1990 | Marsh JW, Srinivasachar K, Neville DM. Antibody-toxin conjugation. Cancer Treatment and Research. 37: 213-37. PMID 2908626 DOI: 10.1007/978-1-4613-1083-9_13 | 0.337 | |||
| 1990 | Wellhöner HH, Bigalke H, Borcholte T, Erdmann G, Eschenhagen T, Jung KH, Marxen P, Peukert U, Neville DM, Srinivasachar K. Uptake of antitetanus F(ab')2 fragments into eukaryotic cells. Journal De Physiologie. 84: 206-10. PMID 2074544 | 0.272 | |||
| 1989 | Neville DM, Srinivasachar K, Stone R, Scharff J. Enhancement of immunotoxin efficacy by acid-cleavable cross-linking agents utilizing diphtheria toxin and toxin mutants. The Journal of Biological Chemistry. 264: 14653-61. PMID 2475487 | 0.391 | |||
| 1989 | Srinivasachar K, Neville DM. New protein cross-linking reagents that are cleaved by mild acid. Biochemistry. 28: 2501-9. PMID 2471550 DOI: 10.1021/BI00432A023 | 0.287 | |||
| 1989 | Neville DM, Srinivasachar K, Stone R, Scharff J. Enhancement of Immunotoxin Efficacy by Acid-cleavable Cross-linking Agents Utilizing Diphtheria Toxin and Toxin Mutants Journal of Biological Chemistry. 264: 14653-14661. DOI: 10.1016/s0021-9258(18)63747-0 | 0.25 | |||
| 1988 | Marsh JW, Neville DM. Development of an immunotoxin with in vivo efficacy for murine systems. Annals of the New York Academy of Sciences. 507: 165-71. PMID 3327410 DOI: 10.1111/j.1749-6632.1987.tb45799.x | 0.22 | |||
| 1988 | Marsh JW, Neville DM. A flexible peptide spacer increases the efficacy of holoricin anti-T cell immunotoxins. Journal of Immunology (Baltimore, Md. : 1950). 140: 3674-8. PMID 2896212 | 0.39 | |||
| 1988 | Neville DM. Immunotoxins for in vivo therapy: where are we? Annals of the New York Academy of Sciences. 507: 155-64. PMID 2831768 DOI: 10.1111/j.1749-6632.1987.tb45798.x | 0.211 | |||
| 1987 | Neville DM. Immunotoxins: current use and future prospects in bone marrow transplantation and cancer treatment. Critical Reviews in Therapeutic Drug Carrier Systems. 2: 329-52. PMID 3549005 | 0.385 | |||
| 1987 | Filipovich AH, Vallera DA, Youle RJ, Haake R, Blazar BR, Arthur D, Neville DM, Ramsay NK, McGlave P, Kersey JH. Graft-versus-host disease prevention in allogeneic bone marrow transplantation from histocompatible siblings. A pilot study using immunotoxins for T cell depletion of donor bone marrow. Transplantation. 44: 62-9. PMID 3299923 DOI: 10.1097/00007890-198707000-00015 | 0.611 | |||
| 1986 | Marsh JW, Neville DM. Kinetic comparison of ricin immunotoxins: biricin conjugate has potentiated cytotoxicity. Biochemistry. 25: 4461-7. PMID 3489484 DOI: 10.1021/BI00363A044 | 0.323 | |||
| 1985 | Kersey JH, Vallera D, Ramsay N, Filipovich A, Youle R, Neville D, Stong R, LeBien T. Monoclonal antibodies and immunotoxins in bone marrow transplantation: purging marrow of ALL or GVHD cells with preservation of stem cells. Haematology and Blood Transfusion. 29: 34-8. PMID 3896970 DOI: 10.1007/978-3-642-70385-0_6 | 0.413 | |||
| 1984 | Quinones RR, Youle RJ, Kersey JH, Zanjani ED, Azemove SM, Soderling CC, Lebien TW, Beverley PC, Neville DM, Vallera DA. Anti-T cell monoclonal antibodies conjugated to ricin as potential reagents for human GVHD prophylaxis: effect on the generation of cytotoxic T cells in both peripheral blood and bone marrow. Journal of Immunology (Baltimore, Md. : 1950). 132: 678-83. PMID 6606676 | 0.627 | |||
| 1984 | Filipovich AH, Vallera DA, Youle RJ, Quinones RR, Neville DM, Kersey JH. Ex-vivo treatment of donor bone marrow with anti-T-cell immunotoxins for prevention of graft-versus-host disease. Lancet (London, England). 1: 469-72. PMID 6142206 DOI: 10.1016/S0140-6736(84)92847-2 | 0.614 | |||
| 1984 | Vallera DA, Kersey JH, Neville DM, Youle RJ. Use of Monoclonal Antibody-Intact Ricin Conjugates in Experimental Allogeneic Bone Marrow Transplantation Protides of the Biological Fluids. 31: 769-774. DOI: 10.1016/B978-0-08-030764-0.50175-0 | 0.576 | |||
| 1983 | Vallera DA, Ash RC, Zanjani ED, Kersey JH, Lebien TW, Beverley PCL, Neville DM, Youle RJ. Anti-T-Cell reagents for human bone marrow transplantation: Ricin linked to three monoclonal antibodies Science. 222: 512-515. PMID 6353579 DOI: 10.1126/Science.6353579 | 0.633 | |||
| 1983 | Vallera DA, Youle RJ, Neville DM, Soderling CCB, Kersey JH. Monoclonal antibody toxin conjugates for experimental graft-versus-host disease prophylaxis: Reagents selectively reactive with t cells and not murine stem cells Transplantation. 36: 73-80. PMID 6346616 DOI: 10.1097/00007890-198307000-00015 | 0.65 | |||
| 1982 | Neville DM, Youle RJ. Monoclonal antibody-ricin or ricin A chain hybrids: kinetic analysis of cell killing for tumor therapy. Immunological Reviews. 62: 75-91. PMID 7042541 DOI: 10.1111/J.1600-065X.1982.Tb00390.X | 0.542 | |||
| 1982 | Volkman DJ, Ahmad A, Fauci AS, Neville DM. Selective abrogation of antigen-specific human B cell responses by antigen-ricin conjugates. The Journal of Experimental Medicine. 156: 634-9. PMID 6980259 DOI: 10.1084/JEM.156.2.634 | 0.304 | |||
| 1982 | Vallera DA, Youle RJ, Neville DM, Kersey JH. Bone marrow transplantation across major histocompatibility barriers. V. Protection of mice from lethal graft-vs.-host disease by pretreatment of donor cells with monoclonal anti-Thy-1.2 coupled to the toxin ricin Journal of Experimental Medicine. 155: 949-954. PMID 6120991 DOI: 10.1084/jem.155.3.949 | 0.64 | |||
| 1982 | Youle RJ, Neville DM. Kinetics of protein synthesis inactivation by ricin-anti-Thy 1.1 monoclonal antibody hybrids. Role of the ricin B subunit demonstrated by reconstitution. The Journal of Biological Chemistry. 257: 1598-601. PMID 6120167 | 0.55 | |||
| 1981 | Youle RJ, Murray GJ, Neville DM. Studies on the galactose-binding site of ricin and the hybrid toxin man6P-ricin Cell. 23: 551-559. PMID 7471212 DOI: 10.1016/0092-8674(81)90151-3 | 0.533 | |||
| 1981 | Youle RJ, Neville DM. Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin. Proceedings of the National Academy of Sciences of the United States of America. 77: 5483-6. PMID 6968914 DOI: 10.1073/Pnas.77.9.5483 | 0.613 | |||
| 1981 | Robbins AR, Myerowitz R, Youle RJ, Murray GJ, Neville DM. The mannose 6-phosphate receptor of Chinese hamster ovary cells. Isolation of mutants with altered receptors Journal of Biological Chemistry. 256: 10618-10622. PMID 6270122 | 0.52 | |||
| 1980 | Neville DM, Murray GJ, Youle RJ. Directed entry of hybrid proteins into cells via alternative receptors Biochemical Society Transactions. 8: 692-693. PMID 7461253 DOI: 10.1042/Bst0080692 | 0.527 | |||
| 1979 | Youle RJ, Neville DM. Receptor-mediated transport of the hybrid protein ricin-diphtheria toxin fragment A with subsequent ADP-ribosylation of intracellular elongation factor II. The Journal of Biological Chemistry. 254: 11089-96. PMID 500625 | 0.532 | |||
| 1979 | Youle RJ, Murray GJ, Neville DM. Ricin linked to monophosphopentamannose binds to fibroblast lysosomal hydrolase receptors, resulting in a cell-type-specific toxin Proceedings of the National Academy of Sciences of the United States of America. 76: 5559-5562. PMID 293662 DOI: 10.1073/Pnas.76.11.5559 | 0.551 | |||
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