Philip W. Ingham, BA DPhil - Publications

Affiliations: 
2013- Lee Kong Chian School of Medicine Nanyang Technological University, Singapore, Singapore 
Area:
Hedgehog signalling

156 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Ingham PW, Nakano Y. Cell Patterning and Segment Polarity Genes in Drosophila: (pattern formation/Drosophila/Cell interacton/Signal transduction/Segment polarity genes). Development, Growth & Differentiation. 32: 563-574. PMID 37281696 DOI: 10.1111/j.1440-169X.1990.00563.x  0.576
2022 Zhang H, Huang Z, Lv L, Xin Y, Wang Q, Li F, Dong L, Wu C, Ingham PW, Zhao Z. A transgenic zebrafish for visualization of cilia. Open Biology. 12: 220104. PMID 35946311 DOI: 10.1098/rsob.220104  0.328
2022 Ingham PW. Hedgehog signaling. Current Topics in Developmental Biology. 149: 1-58. PMID 35606054 DOI: 10.1016/bs.ctdb.2022.04.003  0.358
2019 Saunders TE, Ingham PW. Open questions: how to get developmental biology into shape? Bmc Biology. 17: 17. PMID 30795745 DOI: 10.1186/s12915-019-0636-6  0.331
2018 Ingham PW. From segmentation to human cancer therapy. Development (Cambridge, England). 145. PMID 30413531 DOI: 10.1242/dev.168898  0.412
2018 Yin J, Lee R, Ono Y, Ingham PW, Saunders TE. Spatiotemporal Coordination of FGF and Shh Signaling Underlies the Specification of Myoblasts in the Zebrafish Embryo. Developmental Cell. 46: 735-750.e4. PMID 30253169 DOI: 10.1016/j.devcel.2018.08.024  0.396
2018 Ojeda Naharros I, Cristian FB, Zang J, Gesemann M, Ingham PW, Neuhauss SCF, Bachmann-Gagescu R. Publisher Correction: The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance. Scientific Reports. 8: 12534. PMID 30120317 DOI: 10.1038/s41598-018-30671-8  0.304
2018 Pusapati GV, Kong JH, Patel BB, Gouti M, Sagner A, Sircar R, Luchetti G, Ingham PW, Briscoe J, Rohatgi R. G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog. Science Signaling. 11. PMID 29438014 DOI: 10.1126/Scisignal.Aao5749  0.433
2018 Naharros IO, Cristian FB, Zang J, Gesemann M, Ingham PW, Neuhauss SCF, Bachmann-Gagescu R. The ciliopathy protein TALPID3/KIAA0586 acts upstream of Rab8 activation in zebrafish photoreceptor outer segment formation and maintenance. Scientific Reports. 8: 2211. PMID 29396404 DOI: 10.1038/s41598-018-20489-9  0.373
2017 Ahmed MU, Maurya AK, Cheng L, Jorge EC, Schubert FR, Maire P, Basson MA, Ingham PW, Dietrich S. Engrailed controls epaxial-hypaxial muscle innervation and the establishment of vertebrate three-dimensional mobility. Developmental Biology. PMID 28807781 DOI: 10.1016/j.ydbio.2017.08.011  0.355
2017 Yin J, Lee R, Ono Y, Ingham P, Saunders T. The non-autonomous role of FGF signaling in muscle pioneer determination Mechanisms of Development. 145: S160. DOI: 10.1016/j.mod.2017.04.456  0.302
2017 Eve A, Donnelly J, Wideman J, Richards T, Rentzsch F, Ingham P. Evolutionary origins of the Hedgehog signalling pathway Mechanisms of Development. 145: S106. DOI: 10.1016/J.Mod.2017.04.280  0.365
2017 Ingham P, Kallakuri S. Role of hedgehog signaling in developmental vascular integrity Mechanisms of Development. 145: S53. DOI: 10.1016/j.mod.2017.04.101  0.33
2016 Gurung R, Ono Y, Baxendale S, Lee SL, Moore S, Calvert M, Ingham PW. The Zebrafish frozen Mutant Is a Model for Human Myopathy Associated with Mutation of the Unconventional Myosin MYO18B. Genetics. PMID 27879346 DOI: 10.1534/genetics.116.192864  0.354
2016 Zhao Z, Lee RT, Pusapati GV, Iyu A, Rohatgi R, Ingham PW. An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. Embo Reports. PMID 27113758 DOI: 10.15252/Embr.201541532  0.399
2016 Ingham PW. Drosophila Segment Polarity Mutants and the Rediscovery of the Hedgehog Pathway Genes. Current Topics in Developmental Biology. 116: 477-88. PMID 26970635 DOI: 10.1016/bs.ctdb.2016.01.007  0.467
2016 Leow SC, Poschmann J, Too PG, Yin J, Joseph R, McFarlane C, Dogra S, Shabbir A, Ingham PW, Prabhakar S, Leow MK, Lee YS, Ng KL, Chong YS, Gluckman PD, et al. The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis. Development (Cambridge, England). PMID 26893351 DOI: 10.1242/dev.131573  0.344
2016 Ingham PW. Drosophila Segment Polarity Mutants and the Rediscovery of the Hedgehog Pathway Genes Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2016.01.007  0.302
2015 Ono Y, Yu W, Jackson HE, Parkin CA, Ingham PW. Adaxial cell migration in the zebrafish embryo is an active cell autonomous property that requires the Prdm1a transcription factor. Differentiation; Research in Biological Diversity. 89: 77-86. PMID 25861970 DOI: 10.1016/j.diff.2015.03.002  0.359
2014 Ingham P, Vicente C. An interview with Phil Ingham Development. 141: 2363-2365. PMID 24917495 DOI: 10.1242/Dev.110890  0.335
2014 Venkatesh B, Lee AP, Ravi V, Maurya AK, Korzh V, Lim ZW, Ingham PW, Boehm T, Brenner S, Warren WC. On the origin of SCPP genes. Evolution & Development. 16: 125-6. PMID 24798313 DOI: 10.1111/Ede.12072  0.345
2014 van Impel A, Zhao Z, Hermkens DM, Roukens MG, Fischer JC, Peterson-Maduro J, Duckers H, Ober EA, Ingham PW, Schulte-Merker S. Divergence of zebrafish and mouse lymphatic cell fate specification pathways. Development (Cambridge, England). 141: 1228-38. PMID 24523456 DOI: 10.1242/dev.105031  0.413
2014 Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, et al. Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution. Journal of Immunology (Baltimore, Md. : 1950). 192: 1796-805. PMID 24431232 DOI: 10.4049/jimmunol.1300087  0.312
2014 Wang X, Robertson AL, Li J, Chai RJ, Haishan W, Sadiku P, Ogryzko NV, Everett M, Yoganathan K, Luo HR, Renshaw SA, Ingham PW. Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library. Disease Models & Mechanisms. 7: 163-9. PMID 24291762 DOI: 10.1242/dmm.012047  0.301
2013 Maurya AK, Ben J, Zhao Z, Lee RT, Niah W, Ng AS, Iyu A, Yu W, Elworthy S, van Eeden FJ, Ingham PW. Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo. Plos Genetics. 9: e1003955. PMID 24339784 DOI: 10.1371/journal.pgen.1003955  0.474
2013 Wang X, Zhao Z, Muller J, Iyu A, Khng AJ, Guccione E, Ruan Y, Ingham PW. Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish. Biology Open. 2: 1203-13. PMID 24244857 DOI: 10.1242/bio.20136262  0.394
2013 Nachtergaele S, Whalen DM, Mydock LK, Zhao Z, Malinauskas T, Krishnan K, Ingham PW, Covey DF, Siebold C, Rohatgi R. Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling. Elife. 2: e01340. PMID 24171105 DOI: 10.7554/Elife.01340  0.378
2013 Hynes NE, Ingham PW, Lim WA, Marshall CJ, Massagué J, Pawson T. Signalling change: signal transduction through the decades. Nature Reviews. Molecular Cell Biology. 14: 393-8. PMID 23636498 DOI: 10.1038/Nrm3581  0.394
2013 Carney TJ, Ingham PW. Drugging Hedgehog: signaling the pathway to translation. Bmc Biology. 11: 37. PMID 23587183 DOI: 10.1186/1741-7007-11-37  0.346
2013 Hewamadduma CA, Grierson AJ, Ma TP, Pan L, Moens CB, Ingham PW, Ramesh T, Shaw PJ. Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish. Human Molecular Genetics. 22: 2376-86. PMID 23427147 DOI: 10.1093/Hmg/Ddt082  0.375
2013 Nachtergaele S, Whalen DM, Mydock LK, Zhao Z, Malinauskas T, Krishnan K, Ingham PW, Covey DF, Siebold C, Rohatgi R. Author response: Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling Elife. DOI: 10.7554/Elife.01340.020  0.327
2012 Ingham PW. Zebrafish genetics gets the Scube on Hedgehog secretion. Genes & Development. 26: 2468-70. PMID 23154980 DOI: 10.1101/gad.207126.112  0.354
2012 Baxendale S, Holdsworth CJ, Meza Santoscoy PL, Harrison MR, Fox J, Parkin CA, Ingham PW, Cunliffe VT. Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures. Disease Models & Mechanisms. 5: 773-84. PMID 22730455 DOI: 10.1242/Dmm.010090  0.327
2012 Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ. Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish. Blood. 120: 477-88. PMID 22668851 DOI: 10.1182/blood-2011-10-383729  0.344
2012 Hewamadduma C, Grierson A, Moens C, Pan L, Ma T, Ingham P, Ramesh T, Shaw P. A novel alternative splicing event rescues the mutant tardbp phenotype in a zebrafish model of TDP-43 related Amyotrophic Lateral Sclerosis (ALS) (P03.180) Neurology. 78: P03.180-P03.180. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P03.180  0.335
2011 Ben J, Elworthy S, Ng AS, van Eeden F, Ingham PW. Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates. Development (Cambridge, England). 138: 4969-78. PMID 22028029 DOI: 10.1242/dev.070862  0.487
2011 Seger C, Hargrave M, Wang X, Chai RJ, Elworthy S, Ingham PW. Analysis of Pax7 expressing myogenic cells in zebrafish muscle development, injury, and models of disease. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 2440-51. PMID 21954137 DOI: 10.1002/dvdy.22745  0.322
2011 Korzh S, Winata CL, Zheng W, Yang S, Yin A, Ingham P, Korzh V, Gong Z. The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development Developmental Biology. 359: 262-276. PMID 21925490 DOI: 10.1016/J.Ydbio.2011.08.024  0.307
2011 Wang X, Ono Y, Tan SC, Chai RJ, Parkin C, Ingham PW. Prdm1a and miR-499 act sequentially to restrict Sox6 activity to the fast-twitch muscle lineage in the zebrafish embryo. Development (Cambridge, England). 138: 4399-404. PMID 21880783 DOI: 10.1242/dev.070516  0.327
2011 Elks PM, van Eeden FJ, Dixon G, Wang X, Reyes-Aldasoro CC, Ingham PW, Whyte MK, Walmsley SR, Renshaw SA. Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model. Blood. 118: 712-22. PMID 21555741 DOI: 10.1182/blood-2010-12-324186  0.313
2011 Ingham PW, Nakano Y, Seger C. Mechanisms and functions of Hedgehog signalling across the metazoa. Nature Reviews. Genetics. 12: 393-406. PMID 21502959 DOI: 10.1038/Nrg2984  0.583
2011 Maurya AK, Tan H, Souren M, Wang X, Wittbrodt J, Ingham PW. Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome. Development (Cambridge, England). 138: 755-65. PMID 21266411 DOI: 10.1242/dev.062521  0.472
2011 Ingham PW. Evolutionary Divergence in the Hedgehog Pathway Developmental Cell. 21: e2. DOI: 10.1016/j.devcel.2011.06.032  0.416
2010 Kim HR, Richardson J, van Eeden F, Ingham PW. Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish. Bmc Biology. 8: 65. PMID 20487519 DOI: 10.1186/1741-7007-8-65  0.45
2010 Maurya A, Ingham PW. O6. Cell fate specification in the zebrafish myotome: A paradigm for cross-talk between the Hedgehog and BMP signalling pathways Differentiation. 80: S7-S8. DOI: 10.1016/J.DIFF.2010.09.149  0.461
2009 Ingham PW, McMahon AP. Hedgehog signalling: Kif7 is not that fishy after all. Current Biology : Cb. 19: R729-31. PMID 19906571 DOI: 10.1016/J.Cub.2009.07.060  0.397
2009 Packham IM, Gray C, Heath PR, Hellewell PG, Ingham PW, Crossman DC, Milo M, Chico TJ. Microarray profiling reveals CXCR4a is downregulated by blood flow in vivo and mediates collateral formation in zebrafish embryos. Physiological Genomics. 38: 319-27. PMID 19509081 DOI: 10.1152/physiolgenomics.00049.2009  0.335
2009 Ingham PW. The power of the zebrafish for disease analysis. Human Molecular Genetics. 18: R107-12. PMID 19297397 DOI: 10.1093/hmg/ddp091  0.301
2009 Hammond KL, Baxendale S, McCauley DW, Ingham PW, Whitfield TT. Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling. Evolution & Development. 11: 27-40. PMID 19196331 DOI: 10.1111/j.1525-142X.2008.00300.x  0.413
2009 Parkin CA, Allen CE, Ingham PW. Hedgehog signalling is required for cloacal development in the zebrafish embryo. The International Journal of Developmental Biology. 53: 45-57. PMID 19123126 DOI: 10.1387/ijdb.082669cp  0.426
2009 Kim HR, Ingham PW. The extracellular matrix protein TGFBI promotes myofibril bundling and muscle fibre growth in the zebrafish embryo. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 56-65. PMID 19097068 DOI: 10.1002/dvdy.21812  0.322
2009 Baxendale S, Chen CK, Tang H, Davison C, Hateren LV, Croning MD, Humphray SJ, Hubbard SJ, Ingham PW. Expression screening and annotation of a zebrafish myoblast cDNA library. Gene Expression Patterns : Gep. 9: 73-82. PMID 19007914 DOI: 10.1016/j.gep.2008.10.003  0.383
2009 Ingham P. S21-05. Hedgehog signalling and cell diversity in the zebrafish myotome Mechanisms of Development. 126: S23. DOI: 10.1016/j.mod.2009.06.1000  0.362
2008 Currie PD, Schilling TF, Ingham PW. Small-scale marker-based screening for mutations in zebrafish development. Methods in Molecular Biology (Clifton, N.J.). 461: 493-512. PMID 19030819 DOI: 10.1007/978-1-60327-483-8_34  0.435
2008 von Hofsten J, Elworthy S, Gilchrist MJ, Smith JC, Wardle FC, Ingham PW. Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo. Embo Reports. 9: 683-9. PMID 18535625 DOI: 10.1038/Embor.2008.73  0.417
2008 Elworthy S, Hargrave M, Knight R, Mebus K, Ingham PW. Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity. Development (Cambridge, England). 135: 2115-26. PMID 18480160 DOI: 10.1242/dev.015719  0.39
2008 Pagnon-Minot A, Malbouyres M, Haftek-Terreau Z, Kim HR, Sasaki T, Thisse C, Thisse B, Ingham PW, Ruggiero F, Le Guellec D. Collagen XV, a novel factor in zebrafish notochord differentiation and muscle development. Developmental Biology. 316: 21-35. PMID 18281032 DOI: 10.1016/j.ydbio.2007.12.033  0.391
2008 Parkin CA, Ingham PW. The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G363-7. PMID 18063705 DOI: 10.1152/ajpgi.00457.2007  0.396
2007 Brunk K, Vernay B, Griffith E, Reynolds NL, Strutt D, Ingham PW, Jackson AP. Microcephalin coordinates mitosis in the syncytial Drosophila embryo. Journal of Cell Science. 120: 3578-88. PMID 17895363 DOI: 10.1242/jcs.014290  0.39
2007 Moore CA, Parkin CA, Bidet Y, Ingham PW. A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion. Development (Cambridge, England). 134: 3145-53. PMID 17670792 DOI: 10.1242/dev.001214  0.443
2007 Svetic V, Hollway GE, Elworthy S, Chipperfield TR, Davison C, Adams RJ, Eisen JS, Ingham PW, Currie PD, Kelsh RN. Sdf1a patterns zebrafish melanophores and links the somite and melanophore pattern defects in choker mutants. Development (Cambridge, England). 134: 1011-22. PMID 17267445 DOI: 10.1242/dev.02789  0.594
2007 Ingham P. Micromanaging the response to Hedgehog Nature Genetics. 39: 145-146. PMID 17262026 DOI: 10.1038/ng0207-145  0.416
2006 Ingham PW, Placzek M. Orchestrating ontogenesis: variations on a theme by sonic hedgehog. Nature Reviews. Genetics. 7: 841-50. PMID 17047684 DOI: 10.1038/nrg1969  0.373
2005 Ingham PW, Kim HR. Hedgehog signalling and the specification of muscle cell identity in the zebrafish embryo. Experimental Cell Research. 306: 336-42. PMID 15925589 DOI: 10.1016/j.yexcr.2005.03.019  0.333
2005 Keegan BR, Feldman JL, Begemann G, Ingham PW, Yelon D. Retinoic acid signaling restricts the cardiac progenitor pool. Science (New York, N.Y.). 307: 247-9. PMID 15653502 DOI: 10.1126/Science.1101573  0.315
2005 Tay SY, Ingham PW, Roy S. A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo. Development (Cambridge, England). 132: 625-34. PMID 15647323 DOI: 10.1242/dev.01606  0.517
2004 Wolff C, Roy S, Lewis KE, Schauerte H, Joerg-Rauch G, Kirn A, Weiler C, Geisler R, Haffter P, Ingham PW. iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo. Genes & Development. 18: 1565-76. PMID 15198976 DOI: 10.1101/gad.296004  0.516
2004 Nakano Y, Nystedt S, Shivdasani AA, Strutt H, Thomas C, Ingham PW. Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila. Mechanisms of Development. 121: 507-18. PMID 15172682 DOI: 10.1016/J.Mod.2004.04.015  0.786
2004 Nakano Y, Kim HR, Kawakami A, Roy S, Schier AF, Ingham PW. Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo. Developmental Biology. 269: 381-92. PMID 15110707 DOI: 10.1016/j.ydbio.2004.01.022  0.605
2004 Baxendale S, Davison C, Muxworthy C, Wolff C, Ingham PW, Roy S. The B-cell maturation factor Blimp-1 specifies vertebrate slow-twitch muscle fiber identity in response to Hedgehog signaling. Nature Genetics. 36: 88-93. PMID 14702044 DOI: 10.1038/ng1280  0.329
2004 Ingham P. Q & A. Philip Ingham. Current Biology : Cb. 13: R583-4. PMID 12906803 DOI: 10.1016/S0960-9822(03)00516-5  0.373
2003 Thomas C, Ingham PW. Hedgehog signaling in the Drosophila eye and head: an analysis of the effects of different patched trans-heterozygotes. Genetics. 165: 1915-28. PMID 14704176  0.477
2003 Shivdasani AA, Ingham PW. Regulation of stem cell maintenance and transit amplifying cell proliferation by tgf-beta signaling in Drosophila spermatogenesis. Current Biology : Cb. 13: 2065-72. PMID 14653996 DOI: 10.1016/j.cub.2003.10.063  0.351
2003 Wolff C, Roy S, Ingham PW. Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo. Current Biology : Cb. 13: 1169-81. PMID 12867027 DOI: 10.1016/S0960-9822(03)00461-5  0.459
2003 Anderson KV, Ingham PW. The transformation of the model organism: a decade of developmental genetics. Nature Genetics. 33: 285-93. PMID 12610538 DOI: 10.1038/ng1105  0.401
2003 McMahon AP, Ingham PW, Tabin CJ. Developmental roles and clinical significance of hedgehog signaling. Current Topics in Developmental Biology. 53: 1-114. PMID 12509125 DOI: 10.1016/S0070-2153(03)53002-2  0.384
2002 Roy S, Ingham PW. Hedgehogs tryst with the cell cycle. Journal of Cell Science. 115: 4393-7. PMID 12414986 DOI: 10.1242/jcs.00158  0.399
2002 Glise B, Jones DL, Ingham PW. Notch and Wingless modulate the response of cells to Hedgehog signalling in the Drosophila wing. Developmental Biology. 248: 93-106. PMID 12142023 DOI: 10.1006/Dbio.2002.0720  0.79
2001 Ingham PW, McMahon AP. Hedgehog signaling in animal development: paradigms and principles. Genes & Development. 15: 3059-87. PMID 11731473 DOI: 10.1101/Gad.938601  0.478
2001 Ingham PW. Hedgehog signaling: a tale of two lipids. Science (New York, N.Y.). 294: 1879-81. PMID 11729305 DOI: 10.1126/science.1064115  0.415
2001 Roy S, Qiao T, Wolff C, Ingham PW. Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo. Current Biology : Cb. 11: 1358-63. PMID 11553330 DOI: 10.1016/S0960-9822(01)00402-X  0.501
2001 Roy S, Wolff C, Ingham PW. The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryo. Genes & Development. 15: 1563-76. PMID 11410536 DOI: 10.1101/gad.195801  0.355
2001 Strutt H, Thomas C, Nakano Y, Stark D, Neave B, Taylor AM, Ingham PW. Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation. Current Biology : Cb. 11: 608-13. PMID 11369206 DOI: 10.1016/S0960-9822(01)00179-8  0.792
2001 Schilling TF, Prince V, Ingham PW. Plasticity in zebrafish hox expression in the hindbrain and cranial neural crest. Developmental Biology. 231: 201-16. PMID 11180963 DOI: 10.1006/Dbio.2000.9997  0.352
2001 Currie PD, Ingham PW. 1. Induction and patterning of embryonic skeletal muscle cells in the zebrafish Fish Physiology. 18: 1-4,IN1-IN2,5-17. DOI: 10.1016/S1546-5098(01)18002-7  0.339
2000 Ingham PW, Nystedt S, Nakano Y, Brown W, Stark D, van den Heuvel M, Taylor AM. Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein. Current Biology : Cb. 10: 1315-8. PMID 11069117 DOI: 10.1016/S0960-9822(00)00755-7  0.623
2000 Ingham PW. How cholesterol modulates the signal. Current Biology : Cb. 10: R180-3. PMID 10712894 DOI: 10.1016/S0960-9822(00)00346-8  0.333
2000 Odenthal J, van Eeden FJ, Haffter P, Ingham PW, Nüsslein-Volhard C. Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Developmental Biology. 219: 350-63. PMID 10694427 DOI: 10.1006/dbio.1999.9589  0.433
2000 Begemann G, Ingham PW. Developmental regulation of Tbx5 in zebrafish embryogenesis. Mechanisms of Development. 90: 299-304. PMID 10640716 DOI: 10.1016/S0925-4773(99)00246-4  0.439
2000 Brown LA, Rodaway AR, Schilling TF, Jowett T, Ingham PW, Patient RK, Sharrocks AD. Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos. Mechanisms of Development. 90: 237-52. PMID 10640707 DOI: 10.1016/S0925-4773(99)00256-7  0.409
1999 Lewis KE, Currie PD, Roy S, Schauerte H, Haffter P, Ingham PW. Control of muscle cell-type specification in the zebrafish embryo by Hedgehog signalling. Developmental Biology. 216: 469-80. PMID 10642786 DOI: 10.1006/dbio.1999.9519  0.43
1999 Schilling TF, Concordet JP, Ingham PW. Regulation of left-right asymmetries in the zebrafish by Shh and BMP4. Developmental Biology. 210: 277-87. PMID 10357891 DOI: 10.1006/dbio.1999.9214  0.371
1999 Lewis KE, Drossopoulou G, Paton IR, Morrice DR, Robertson KE, Burt DW, Ingham PW, Tickle C. Expression of ptc and gli genes in talpid3 suggests bifurcation in Shh pathway. Development (Cambridge, England). 126: 2397-407. PMID 10225999  0.387
1999 Lewis KE, Concordet JP, Ingham PW. Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to Hedgehog signalling. Developmental Biology. 208: 14-29. PMID 10075838 DOI: 10.1006/dbio.1998.9169  0.5
1998 Ingham PW. Boning up on Hedgehog's movements. Nature. 394: 16-7. PMID 9665119 DOI: 10.1038/27764  0.381
1998 Ingham PW. trithorax and the regulation of homeotic gene expression in Drosophila: a historical perspective. The International Journal of Developmental Biology. 42: 423-9. PMID 9654027 DOI: 10.1387/Ijdb.9654027  0.44
1998 Ingham PW. Transducing Hedgehog: the story so far. The Embo Journal. 17: 3505-11. PMID 9649421 DOI: 10.1093/emboj/17.13.3505  0.414
1998 Currie PD, Ingham PW. The generation and interpretation of positional information within the vertebrate myotome. Mechanisms of Development. 73: 3-21. PMID 9545513 DOI: 10.1016/S0925-4773(98)00036-7  0.432
1998 Ingham PW. The patched gene in development and cancer. Current Opinion in Genetics & Development. 8: 88-94. PMID 9529611 DOI: 10.1016/S0959-437X(98)80067-1  0.464
1997 Rauch GJ, Hammerschmidt M, Blader P, Schauerte HE, Strähle U, Ingham PW, McMahon AP, Haffter P. Wnt5 is required for tail formation in the zebrafish embryo. Cold Spring Harbor Symposia On Quantitative Biology. 62: 227-34. PMID 9598355 DOI: 10.1101/Sqb.1997.062.01.028  0.475
1997 Quirk J, van den Heuvel M, Henrique D, Marigo V, Jones TA, Tabin C, Ingham PW. The smoothened gene and hedgehog signal transduction in Drosophila and vertebrate development. Cold Spring Harbor Symposia On Quantitative Biology. 62: 217-26. PMID 9598354 DOI: 10.1101/Sqb.1997.062.01.027  0.689
1997 Ingham PW. Zebrafish genetics and its implications for understanding vertebrate development. Human Molecular Genetics. 6: 1755-60. PMID 9300668 DOI: 10.1093/hmg/6.10.1755  0.365
1997 Chang BE, Blader P, Fischer N, Ingham PW, Strähle U. Axial (HNF3beta) and retinoic acid receptors are regulators of the zebrafish sonic hedgehog promoter. The Embo Journal. 16: 3955-64. PMID 9233805 DOI: 10.1093/Emboj/16.13.3955  0.428
1996 Blader P, Strähle U, Ingham PW. Three Wnt genes expressed in a wide variety of tissues during development of the zebrafish, Danio rerio: developmental and evolutionary perspectives. Development Genes and Evolution. 206: 3-13. PMID 24173392 DOI: 10.1007/S004270050025  0.479
1996 van den Heuvel M, Ingham PW. 'Smoothening' the path for hedgehogs. Trends in Cell Biology. 6: 451-3. PMID 15157500 DOI: 10.1016/0962-8924(96)84934-8  0.44
1996 Strähle U, Blader P, Ingham PW. Expression of axial and sonic hedgehog in wildtype and midline defective zebrafish embryos. The International Journal of Developmental Biology. 40: 929-40. PMID 8946241  0.303
1996 Forbes AJ, Spradling AC, Ingham PW, Lin H. The role of segment polarity genes during early oogenesis in Drosophila. Development (Cambridge, England). 122: 3283-94. PMID 8898240  0.344
1996 Concordet JP, Lewis KE, Moore JW, Goodrich LV, Johnson RL, Scott MP, Ingham PW. Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development (Cambridge, England). 122: 2835-46. PMID 8787757  0.397
1996 Alexandre C, Jacinto A, Ingham PW. Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. Genes & Development. 10: 2003-13. PMID 8769644 DOI: 10.1101/Gad.10.16.2003  0.761
1996 Van den Heuvel M, Ingham PW. Smoothened encodes a receptor-like serpentine protein required for hedgehog signalling Nature. 382: 547-551. PMID 8700230 DOI: 10.1038/382547a0  0.512
1996 Currie PD, Ingham PW. Induction of a specific muscle cell type by a hedgehog-like protein in zebrafish Nature. 382: 452-455. PMID 8684485 DOI: 10.1038/382452a0  0.308
1996 Forbes AJ, Lin H, Ingham PW, Spradling AC. hedgehog is required for the proliferation and specification of ovarian somatic cells prior to egg chamber formation in Drosophila. Development (Cambridge, England). 122: 1125-35. PMID 8620839  0.312
1996 Currie PD, Jacinto A, Ingham PW. Hedgehog signalling in Drosophila and vertebrate development Netherlands Journal of Zoology. 46: 97-114. DOI: 10.1163/156854295X00087  0.645
1995 Concordet JP, Ingham P. Developmental biology. Patterning goes sonic. Nature. 375: 279-80. PMID 7753187 DOI: 10.1038/375279A0  0.31
1995 Ingham PW, Fietz MJ. Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing Current Biology. 5: 432-440. PMID 7627558 DOI: 10.1016/S0960-9822(95)00084-4  0.497
1995 Ingham PW. Signalling by hedgehog family proteins in Drosophila and vertebrate development Current Opinion in Genetics and Development. 5: 492-498. PMID 7580142 DOI: 10.1016/0959-437X(95)90054-K  0.468
1995 Fietz MJ, Jacinto A, Taylor AM, Alexandre C, Ingham PW. Secretion of the amino-terminal fragment of the hedgehog protein is necessary and sufficient for hedgehog signalling in Drosophila. Current Biology : Cb. 5: 643-50. PMID 7552175 DOI: 10.1016/S0960-9822(95)00129-1  0.744
1994 Paroush Z, Finley RL, Kidd T, Wainwright SM, Ingham PW, Brent R, Ish-Horowicz D. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell. 79: 805-15. PMID 8001118 DOI: 10.1016/0092-8674(94)90070-1  0.773
1994 Ingham PW. Pattern Formation: Hedgehog points the way Current Biology. 4: 347-350. PMID 7922344 DOI: 10.1016/S0960-9822(00)00076-2  0.333
1994 Fietz MJ, Concordet JP, Barbosa R, Johnson R, Krauss S, McMahon AP, Tabin C, Ingham PW. The hedgehog gene family in Drosophila and vertebrate development. Development (Cambridge, England). Supplement. 43-51. PMID 7579523  0.374
1994 Ingham P. The development of Drosophila melanogaster Trends in Genetics. 10: 299. DOI: 10.1016/0168-9525(90)90017-Z  0.338
1993 Forbes AJ, Nakano Y, Taylor AM, Ingham PW. Genetic analysis of hedgehog signalling in the Drosophila embryo. Development (Cambridge, England). 119: 115-24. PMID 27002038  0.633
1993 Taylor AM, Nakano Y, Mohler J, Ingham PW. Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo. Mechanisms of Development. 42: 89-96. PMID 8369225 DOI: 10.1016/0925-4773(93)90101-3  0.668
1993 Krauss S, Concordet JP, Ingham PW. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos Cell. 75: 1431-1444. PMID 8269519 DOI: 10.1016/0092-8674(93)90628-4  0.49
1993 Ingham PW. Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo Nature. 366: 560-562. PMID 8255293 DOI: 10.1038/366560a0  0.529
1993 Ingham PW, Hidalgo A. Regulation of wingless transcription in the Drosophila embryo. Development (Cambridge, England). 117: 283-91. PMID 8223252  0.648
1993 Forbes AJ, Nakano Y, Taylor AM, Ingham PW. Genetic analysis of hedgehog signalling in the Drosophila embryo. Development (Cambridge, England). Supplement. 115-24. PMID 8049467  0.634
1993 Strähle U, Blader P, Henrique D, Ingham PW. Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos. Genes & Development. 7: 1436-46. PMID 7687227 DOI: 10.1101/Gad.7.7B.1436  0.679
1992 Eisenberg LM, Ingham PW, Brown AMC. Cloning and characterization of a novel Drosophila Wnt gene, Dwnt-5, a putative downstream target of the homeobox gene Distal-less Developmental Biology. 154: 73-83. PMID 1358729 DOI: 10.1016/0012-1606(92)90049-M  0.473
1991 Ingham PW. Segment polarity genes and cell patterning within the Drosophila body segment Current Opinion in Genetics and Development. 1: 261-267. PMID 1688007 DOI: 10.1016/S0959-437X(05)80080-2  0.405
1991 Ingham PW, Taylor AM, Nakano Y. Role of the Drosophila patched gene in positional signalling. Nature. 353: 184-7. PMID 1653906 DOI: 10.1038/353184a0  0.663
1990 Phillips RG, Roberts IJ, Ingham PW, Whittle JR. The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs. Development (Cambridge, England). 110: 105-14. PMID 2081453  0.583
1990 Ingham PW, Nakano Y. Cell patterning and segment polarity genes in Drosophila Development Growth and Differentiation. 32: 563-574. DOI: 10.1111/J.1440-169X.1990.00563.X  0.593
1989 Nakano Y, Guerrero I, Hidalgo A, Taylor A, Whittle JR, Ingham PW. A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature. 341: 508-13. PMID 2797178 DOI: 10.1038/341508A0  0.795
1989 Ish-Horowicz D, Pinchin SM, Ingham PW, Gyurkovics HG. Autocatalytic ftz activation and metameric instability induced by ectopic ftz expression. Cell. 57: 223-32. PMID 2495181 DOI: 10.1016/0092-8674(89)90960-4  0.663
1988 Arias AM, Baker NE, Ingham PW. Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo Development. 103: 157-170. PMID 3197626  0.344
1988 Ingham PW. The molecular genetics of embryonic pattern formation in Drosophila Nature. 335: 25-34. PMID 2901040 DOI: 10.1038/335025A0  0.415
1988 Ingham PW, Baker NE, Martinez-Arias A. Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even skipped. Nature. 331: 73-5. PMID 2893285 DOI: 10.1038/331073a0  0.707
1987 Martinez-Arias A, Ingham PW, Scott MP, Akam ME. The spatial and temporal deployment of Dfd and Scr transcripts throughout development of Drosophila. Development (Cambridge, England). 100: 673-83. PMID 2450726  0.633
1986 Martinez-Arias A, Ingham P. Pattern formation: Form and diffusion. Nature. 324: 510-511. PMID 29517744 DOI: 10.1038/324510b0  0.6
1986 Ingham PW, Ish-Horowicz D, Howard KR. Correlative changes in homoeotic and segmentation gene expression in Krüppel mutant embryos of Drosophila. The Embo Journal. 5: 1659-65. PMID 16453692 DOI: 10.1002/J.1460-2075.1986.Tb04409.X  0.68
1986 Howard K, Ingham P. Regulatory interactions between the segmentation genes fushi tarazu, hairy, and engrailed in the Drosophila blastoderm. Cell. 44: 949-957. PMID 3955654 DOI: 10.1016/0092-8674(86)90018-8  0.387
1986 Ingham PW, Martinez-Arias A. The correct activation of Antennapedia and bithorax complex genes requires the fushi tarazu gene. Nature. 324: 592-7. PMID 2878371 DOI: 10.1038/324592a0  0.697
1986 Martinez-Arias A, Ingham P. Pattern formation: Form and diffusion Nature. 324: 510-511. DOI: 10.1038/324510b0  0.566
1985 Ingham PW, Pinchin SM, Howard KR, Ish-Horowicz D. Genetic Analysis of the Hairy Locus in DROSOPHILA MELANOGASTER. Genetics. 111: 463-86. PMID 17246301  0.583
1985 Ingham PW. A clonal analysis of the requirement for the trithorax gene in the diversification of segments in Drosophila Journal of Embryology and Experimental Morphology. 349-365. PMID 4093752  0.332
1985 Martinez-Arias A, Ingham PW. The origin of pattern duplications in segment polarity mutants of Drosophila melanogaster. Journal of Embryology and Experimental Morphology. 87: 129-35. PMID 3928797  0.615
1985 Ish-Horowicz D, Howard KR, Pinchin SM, Ingham PW. Molecular and genetic analysis of the hairy locus in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 50: 135-44. PMID 3006986 DOI: 10.1101/Sqb.1985.050.01.019  0.572
1985 Ingham PW. Genetic control of the spatial pattern of selector gene expression in Drosophila Cold Spring Harbor Symposia On Quantitative Biology. 50: 201-208. PMID 2420511 DOI: 10.1101/Sqb.1985.050.01.026  0.367
1985 Ingham PW, Howard KR, Ish-Horowicz D. Transcription pattern of the Drosophila segmentation gene hairy Nature. 318: 439-445. DOI: 10.1038/318439a0  0.681
1985 Ingham P, Martinez-Arias A, Lawrence PA, Howard K. Expression of engrailed in the parasegment of Drosophila Nature. 317: 634-636. DOI: 10.1038/317634A0  0.648
1985 Ingham PW. Drosophila genetics: Patterns of differentiation Nature. 317: 202-203. DOI: 10.1038/317202a0  0.31
1985 Ingham P. The regulation of the bithorax complex Trends in Genetics. 1: 112-116. DOI: 10.1016/0168-9525(85)90043-5  0.377
1984 Ingham PW. A gene that regulates the bithorax complex differentially in larval and adult cells of Drosophila Cell. 37: 815-823. PMID 6430566 DOI: 10.1016/0092-8674(84)90416-1  0.409
1983 Ingham PW. Differential expression of bithorax complex genes in the absence of the extra sex combs and trithorax genes Nature. 306: 591-593. DOI: 10.1038/306591A0  0.423
1980 Ingham P, Whittle R. Trithorax: A new homoeotic mutation of Drosophila melanogaster causing transformations of abdominal and thoracic imaginal segments Molecular and General Genetics Mgg. 179: 607-614. DOI: 10.1007/BF00271751  0.366
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