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Changkyu Gu, Ph.D. - Publications

Affiliations: 
Massachusetts General Hospital, Boston, MA 
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14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhu K, Mukherjee K, Wei C, Hayek SS, Collins A, Gu C, Corapi K, Altintas MM, Wang Y, Waikar SS, Bianco AC, Koch A, Tacke F, Reiser J, Sever S. The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease. Science Translational Medicine. 15: eabq6492. PMID 37729431 DOI: 10.1126/scitranslmed.abq6492  0.568
2022 Mukherjee K, Gu C, Collins A, Mettlen M, Samelko B, Altintas MM, Sudhini YR, Wang X, Bouley R, Brown D, Pedro BP, Bane SL, Gupta V, Brinkkoetter PT, Hagmann H, et al. Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury. Nature Communications. 13: 2422. PMID 35504916 DOI: 10.1038/s41467-022-30101-4  0.606
2016 Lee H, Noh H, Mun J, Gu C, Sever S, Park S. Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis. Nature Communications. 7: 12799. PMID 27619642 DOI: 10.1038/Ncomms12799  0.61
2016 Gu C, Lee HW, Garborcauskas G, Reiser J, Gupta V, Sever S. Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation. Journal of the American Society of Nephrology : Jasn. PMID 27432739 DOI: 10.1681/Asn.2016010008  0.659
2015 Schiffer M, Teng B, Gu C, Shchedrina VA, Kasaikina M, Pham VA, Hanke N, Rong S, Gueler F, Schroder P, Tossidou I, Park JK, Staggs L, Haller H, Erschow S, et al. Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nature Medicine. 21: 601-9. PMID 25962121 DOI: 10.1038/Nm.3843  0.66
2014 Gu C, Chang J, Shchedrina VA, Pham VA, Hartwig JH, Suphamungmee W, Lehman W, Hyman BT, Bacskai BJ, Sever S. Regulation of dynamin oligomerization in cells: the role of dynamin-actin interactions and its GTPase activity. Traffic (Copenhagen, Denmark). 15: 819-38. PMID 24891099 DOI: 10.1111/Tra.12178  0.651
2013 Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, et al. Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease. The Journal of Biological Chemistry. 288: 36598-609. PMID 24194522 DOI: 10.1074/Jbc.M113.488122  0.624
2013 Sever S, Chang J, Gu C. Dynamin rings: not just for fission. Traffic (Copenhagen, Denmark). 14: 1194-9. PMID 23980695 DOI: 10.1111/Tra.12116  0.648
2012 Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, ... ... Gu C, et al. CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival (The Journal of Clinical Investigation (2011) 121, 10, (3965-3980) DOI: 10.1172/JCI58552) Journal of Clinical Investigation. 122: 780. DOI: 10.1172/Jci62812  0.588
2012 Rayego-Mateos S, Rodrigues-Díez R, Rodrigues-Díez RR, Lavoz-Barria C, Alique M, Mas S, Pato J, Keri G, Egido J, Ortiz A, Ruiz-Ortega M, Ying L, Tepel M, Frank E, Florian T, ... ... Gu C, et al. Mechanisms and targets of glomerular damage Nephrology Dialysis Transplantation. 27. DOI: 10.1093/Ndt/Gfs229  0.571
2011 Yaddanapudi S, Altintas MM, Kistler AD, Fernandez I, Möller CC, Wei C, Peev V, Flesche JB, Forst AL, Li J, Patrakka J, Xiao Z, Grahammer F, Schiffer M, Lohmüller T, ... ... Gu C, et al. CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival. The Journal of Clinical Investigation. 121: 3965-80. PMID 21911934 DOI: 10.1172/Jci58552  0.655
2010 Gu C, Yaddanapudi S, Weins A, Osborn T, Reiser J, Pollak M, Hartwig J, Sever S. Direct dynamin-actin interactions regulate the actin cytoskeleton. The Embo Journal. 29: 3593-606. PMID 20935625 DOI: 10.1038/Emboj.2010.249  0.643
2009 Adair BD, Altintas M, Möller CC, Flesche J, Wei C, Faul C, Campbell K, Gu C, Sever S, Shaw A, Mundel P, Reiser J. CD2AP Structure And Progression Of Renal Disease Biophysical Journal. 96: 132a-133a. DOI: 10.1016/J.Bpj.2008.12.601  0.627
2007 Shin J, Gu C, Park E, Park S. Identification of phosphotyrosine binding domain-containing proteins as novel downstream targets of the EphA8 signaling function. Molecular and Cellular Biology. 27: 8113-26. PMID 17875921 DOI: 10.1128/Mcb.00794-07  0.345
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