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Shahid M. Nimjee, Ph.D. - Publications

Affiliations: 
2005 Duke University, Durham, NC 
Area:
Molecular Biology, Genetics, Pharmaceutical Chemistry
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gray BP, Kelly L, Steen-Burrell KA, Layzer JM, Rempel RE, Nimjee SM, Cooley BC, Tarantal AF, Sullenger BA. Rapid molecular imaging of active thrombi using aptamer-antidote probes. Molecular Therapy. Nucleic Acids. 31: 440-451. PMID 36817726 DOI: 10.1016/j.omtn.2023.01.009  0.512
2022 Shea SM, Thomas KA, Rassam RMG, Mihalko EP, Daniel C, Sullenger BA, Spinella PC, Nimjee SM. Dose-Dependent Von Willebrand Factor Inhibition by Aptamer BB-031 Correlates with Thrombolysis in a Microfluidic Model of Arterial Occlusion. Pharmaceuticals (Basel, Switzerland). 15. PMID 36558901 DOI: 10.3390/ph15121450  0.528
2022 Corey KM, Olson LB, Naqvi IA, Morrison SA, Davis C, Nimjee SM, Que LG, Bachelder RE, Kraft BD, Chen L, Nair SK, Levy JH, Sullenger BA. Exposure and Outcome in practice: a retrospective cohort study between fibrinolytic suppression and hypercoagulability, the severity of hypoxemia, and mortality in COVID-19 patients. Anesthesiology. PMID 35412597 DOI: 10.1097/ALN.0000000000004239  0.462
2020 Zakeri A, Jadhav AP, Sullenger BA, Nimjee SM. Ischemic stroke in COVID-19-positive patients: an overview of SARS-CoV-2 and thrombotic mechanisms for the neurointerventionalist. Journal of Neurointerventional Surgery. PMID 33298508 DOI: 10.1136/neurintsurg-2020-016794  0.495
2020 Wang B, Zhang M, Urabe G, Huang Y, Chen G, Wheeler D, Dornbos DJ, Huttinger A, Nimjee SM, Gong S, Guo LW, Kent KC. PERK Inhibition Mitigates Restenosis and Thrombosis: A Potential Low-Thrombogenic Antirestenotic Paradigm. Jacc. Basic to Translational Science. 5: 245-263. PMID 32215348 DOI: 10.1016/J.Jacbts.2019.12.005  0.326
2019 Nimjee SM, Sullenger BA. Therapeutic Aptamers: Evolving to Find Their Clinical Niche. Current Medicinal Chemistry. PMID 31573879 DOI: 10.2174/0929867326666191001125101  0.593
2019 Schunemann V, Wang JL, Dornbos D, Youssef PP, Sribnick E, Leonard J, Nimjee SM. One and Done: Multimodal treatment of pediatric cerebral arteriovenous malformations in a single anesthesia event. World Neurosurgery. PMID 31279921 DOI: 10.1016/J.Wneu.2019.06.200  0.306
2019 Nimjee SM, Dornbos D, Pitoc GA, Wheeler DG, Layzer JM, Venetos N, Huttinger A, Talentino SE, Musgrave NJ, Moody H, Rempel RE, Jones C, Carlisle K, Wilson J, Bratton C, et al. Preclinical Development of a vWF Aptamer to Limit Thrombosis and Engender Arterial Recanalization of Occluded Vessels. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30987839 DOI: 10.1016/J.Ymthe.2019.03.016  0.622
2018 Huttinger AL, Wheeler DG, Gnyawali S, Dornbos D, Layzer JM, Venetos N, Talentino S, Musgrave NJ, Jones C, Bratton C, Joseph ME, Sen C, Sullenger BA, Nimjee SM. Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury. Journal of Visualized Experiments : Jove. PMID 30247470 DOI: 10.3791/57981  0.546
2018 Dornbos D, Nimjee SM. Reversal of Systemic Anticoagulants and Antiplatelet Therapeutics. Neurosurgery Clinics of North America. 29: 537-545. PMID 30223966 DOI: 10.1016/J.Nec.2018.06.005  0.351
2018 Zakeri AS, Nimjee SM. Use of Antiplatelet Agents in the Neurosurgical Patient. Neurosurgery Clinics of North America. 29: 517-527. PMID 30223964 DOI: 10.1016/J.Nec.2018.06.004  0.372
2018 Talentino SE, Joseph ME, Byington CM, Bratton CF, Hatten CM, Shimmin GS, Anderson CP, Wilson JL, Huttinger AL, Wheeler DG, Nimjee SM. Abstract 228: RNA Aptamer 9.14T79VRT7 Modifies Canine Ex vivo Platelet Reactivity Circulation Research. 123. DOI: 10.1161/Res.123.Suppl_1.228  0.316
2018 Wilson J, Wheeler D, Huttinger A, Anderson C, Talentino S, Balch M, Rink C, Nimjee S. Abstract 522: VWF Inhibition by an RNA Aptamer Improves Functional Outcome Compared to rTPA in Ferric Chloride-induced Carotid Artery Thrombosis in Mice Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.522  0.314
2017 Dornbos D, Karras CL, Wenger N, Priddy B, Youssef P, Nimjee SM, Powers CJ. Pipeline embolization device for recurrence of previously treated aneurysms. Neurosurgical Focus. 42: E8. PMID 28565989 DOI: 10.3171/2017.3.Focus1744  0.302
2017 Dornbos D, Katz JS, Youssef P, Powers CJ, Nimjee SM. Glycoprotein IIb/IIIa Inhibitors in Prevention and Rescue Treatment of Thromboembolic Complications During Endovascular Embolization of Intracranial Aneurysms. Neurosurgery. PMID 28472526 DOI: 10.1093/Neuros/Nyx170  0.368
2017 Nimjee SM, White RR, Becker RC, Sullenger BA. Aptamers as Therapeutics. Annual Review of Pharmacology and Toxicology. 57: 61-79. PMID 28061688 DOI: 10.1146/Annurev-Pharmtox-010716-104558  0.604
2016 Nimjee SM, Povsic TJ, Sullenger BA, Becker RC. Translation and Clinical Development of Antithrombotic Aptamers. Nucleic Acid Therapeutics. PMID 26882082 DOI: 10.1089/Nat.2015.0581  0.606
2015 Britz GW, Agarwal V, Mihlon F, Ramanathan D, Agrawal A, Nimjee SM, Kaylie D. Radial Artery Bypass for Intractable Vertebrobasilar Insufficiency: Case Series and Review of the Literature. World Neurosurgery. PMID 26284960 DOI: 10.1016/J.Wneu.2015.08.004  0.318
2015 Nimjee SM. Endovascular Intracranial Micro-Catheter Placement to Treat Cavernous Sinus Thrombosis Journal of Neurology & Neurophysiology. 6. DOI: 10.4172/2155-9562.1000309  0.326
2014 Agarwal A, Gokhale S, Gupta J, Raju R, Nimjee S, Smith T, Britz GW. Use of pipeline flow diverting stents for wide neck intracranial aneurysms: A retrospective institutional review. Asian Journal of Neurosurgery. 9: 3-6. PMID 24891883 DOI: 10.4103/1793-5482.131057  0.304
2014 Lewis DA, Nimjee SM, Pitoc GA, Khan S, Becker RC, Sullenger BA, Ortel TL. Laboratory Assessment of Anti-Coagulant Properties of a Von Willebrand Factor Targeted Aptamer Blood. 124: 4279-4279. DOI: 10.1182/Blood.V124.21.4279.4279  0.574
2013 Caputo AM, Gottfried ON, Nimjee SM, Brown CR, Michael KW, Richardson WJ. Spinal Epidural Hematoma Following Epidural Steroid Injection in a Patient Treated with Dabigatran: A Case Report. Jbjs Case Connector. 3: e64. PMID 29252220 DOI: 10.2106/Jbjs.Cc.M.00011  0.31
2012 Bompiani KM, Woodruff RS, Becker RC, Nimjee SM, Sullenger BA. Antidote control of aptamer therapeutics: the road to a safer class of drug agents. Current Pharmaceutical Biotechnology. 13: 1924-34. PMID 22352726 DOI: 10.2174/138920112802273137  0.757
2012 Nimjee SM, Lohrmann JD, Wang H, Snyder DJ, Cummings TJ, Becker RC, Oney S, Sullenger BA. Rapidly regulating platelet activity in vivo with an antidote controlled platelet inhibitor. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 391-7. PMID 22086230 DOI: 10.1038/Mt.2011.226  0.761
2011 Burnette AD, Nimjee SM, Batchvarova M, Zennadi R, Telen MJ, Nishimura J, Sullenger BA. RNA aptamer therapy for vaso-occlusion in sickle cell disease. Nucleic Acid Therapeutics. 21: 275-83. PMID 21793788 DOI: 10.1089/Nat.2010.0270  0.554
2009 Nimjee SM, Oney S, Volovyk Z, Bompiani KM, Long SB, Hoffman M, Sullenger BA. Synergistic effect of aptamers that inhibit exosites 1 and 2 on thrombin. Rna (New York, N.Y.). 15: 2105-11. PMID 19846574 DOI: 10.1261/Rna.1240109  0.727
2009 Nimjee S, Sullenger B. Aptamers in the clinic Drugs of the Future. 34: 897. DOI: 10.1358/Dof.2009.034.11.1445907  0.518
2008 Blake CM, Oney S, Nimjee SM, Sullenger BA. Aptamers and siRNAs in cardiovascular disease Rna Technologies in Cardiovascular Medicine and Research. 255-287. DOI: 10.1007/978-3-540-78709-9_13  0.728
2007 Oney S, Nimjee SM, Layzer J, Que-Gewirth N, Ginsburg D, Becker RC, Arepally G, Sullenger BA. Antidote-controlled platelet inhibition targeting von Willebrand factor with aptamers. Oligonucleotides. 17: 265-74. PMID 17854267 DOI: 10.1089/Oli.2007.0089  0.763
2006 McGirt MJ, Blessing R, Alexander MJ, Nimjee SM, Woodworth GF, Friedman AH, Graffagnino C, Laskowitz DT, Lynch JR. Risk of cerebral vasopasm after subarachnoid hemorrhage reduced by statin therapy: A multivariate analysis of an institutional experience. Journal of Neurosurgery. 105: 671-4. PMID 17121126 DOI: 10.3171/Jns.2006.105.5.671  0.326
2006 Nimjee SM, Keys JR, Pitoc GA, Quick G, Rusconi CP, Sullenger BA. A novel antidote-controlled anticoagulant reduces thrombin generation and inflammation and improves cardiac function in cardiopulmonary bypass surgery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 408-15. PMID 16765093 DOI: 10.1016/J.Ymthe.2006.04.006  0.575
2006 Nishimura J, Burnette AD, Batchvarova M, Nimjee SM, Zennadi R, Sullenger BA, Telen MJ. Blocking Adhesion of Sickle Erythrocytes to Endothelial αVβ3 Using RNA Aptamer. Blood. 108: 688-688. DOI: 10.1182/Blood.V108.11.688.688  0.594
2006 Nimjee SM, Rusconi CP, Sullenger BA. Aptamers to Proteins The Aptamer Handbook: Functional Oligonucleotides and Their Applications. 131-166. DOI: 10.1002/3527608192.ch6  0.434
2005 Mi J, Zhang X, Giangrande PH, McNamara JO, Nimjee SM, Sarraf-Yazdi S, Sullenger BA, Clary BM. Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival. Biochemical and Biophysical Research Communications. 338: 956-63. PMID 16256939 DOI: 10.1016/J.Bbrc.2005.10.043  0.565
2005 Nimjee SM, Rusconi CP, Harrington RA, Sullenger BA. The potential of aptamers as anticoagulants. Trends in Cardiovascular Medicine. 15: 41-5. PMID 15795162 DOI: 10.1016/J.Tcm.2005.01.002  0.581
2005 Nimjee SM, Rusconi CP, Sullenger BA. Aptamers: an emerging class of therapeutics. Annual Review of Medicine. 56: 555-83. PMID 15660527 DOI: 10.1146/Annurev.Med.56.062904.144915  0.601
2005 Nishimura J, Nimjee SM, Jiang H, Howard TA, Pitoc GA, Rusconi CP, Omine M, Chao NJ, Frank MM, Sullenger BA, Ware RE. Blocking Complement-Mediated Hemolysis Using RNA Aptamers That Bind Complement Component C8. Blood. 106: 186-186. DOI: 10.1182/Blood.V106.11.186.186  0.549
2004 Rusconi CP, Roberts JD, Pitoc GA, Nimjee SM, White RR, Quick G, Scardino E, Fay WP, Sullenger BA. Antidote-mediated control of an anticoagulant aptamer in vivo. Nature Biotechnology. 22: 1423-8. PMID 15502817 DOI: 10.1038/Nbt1023  0.544
2004 Nishimura J, Nimjee S, Jiang H, Kawaguchi T, Nakakuma H, Omine M, Frank MM, Ware RE, Sullenger BA. Blocking Complement-Mediated Hemolysis of PNH Erythrocytes by RNA Aptamers to C8 and C9. Blood. 104: 2824-2824. DOI: 10.1182/Blood.V104.11.2824.2824  0.55
2003 Nimjee SM, Sullenger BA. The Sabiston vision of basic science in a department of surgery. Annals of Surgery. 238: S28-32. PMID 14703741 DOI: 10.1097/01.Sla.0000097106.09512.Ab  0.488
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