| Year |
Citation |
Score |
| 2024 |
Puri S, Maachi H, Nair G, Russ HA, Chen R, Pulimeno P, Cutts Z, Ntranos V, Hebrok M. Sox9 regulates alternative splicing and pancreatic beta cell function. Nature Communications. 15: 588. PMID 38238288 DOI: 10.1038/s41467-023-44384-8 |
0.401 |
|
| 2023 |
Cha J, Tong X, Walker EM, Dahan T, Cochrane VA, Ashe S, Russell R, Osipovich AB, Mawla AM, Guo M, Liu JH, Loyd ZA, Huising MO, Magnuson MA, Hebrok M, et al. Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity. Jci Insight. 8. PMID 37606041 DOI: 10.1172/jci.insight.166386 |
0.614 |
|
| 2023 |
de Klerk E, Xiao Y, Emfinger CH, Keller MP, Berrios DI, Loconte V, Ekman AA, White KL, Cardone RL, Kibbey RG, Attie AD, Hebrok M. Loss of ZNF148 enhances insulin secretion in human pancreatic β cells. Jci Insight. 8. PMID 37288664 DOI: 10.1172/jci.insight.157572 |
0.346 |
|
| 2022 |
Chai S, Kim Y, Galivo F, Dorrell C, Wakefield L, Posey J, Ackermann AM, Kaestner KH, Hebrok M, Grompe M. Development of a beta cell-specific expression control element for rAAV. Human Gene Therapy. PMID 35297680 DOI: 10.1089/hum.2021.219 |
0.355 |
|
| 2022 |
Parent AV, Ashe S, Nair GG, Li ML, Chavez J, Liu JS, Zhong Y, Streeter PR, Hebrok M. Development of a scalable method to isolate subsets of stem cell-derived pancreatic islet cells. Stem Cell Reports. PMID 35245441 DOI: 10.1016/j.stemcr.2022.02.001 |
0.344 |
|
| 2021 |
Heller S, Li Z, Lin Q, Geusz R, Breunig M, Hohwieler M, Zhang X, Nair GG, Seufferlein T, Hebrok M, Sander M, Julier C, Kleger A, Costa IG. Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation. Communications Biology. 4: 1298. PMID 34789845 DOI: 10.1038/s42003-021-02818-3 |
0.354 |
|
| 2021 |
Kerper N, Ashe S, Hebrok M. Pancreatic β-Cell Development and Regeneration. Cold Spring Harbor Perspectives in Biology. PMID 34580120 DOI: 10.1101/cshperspect.a040741 |
0.365 |
|
| 2021 |
Hendley AM, Rao AA, Leonhardt L, Ashe S, Smith JA, Giacometti S, Peng XL, Jiang H, Berrios D, Pawlak M, Li LY, Lee J, Collisson EA, Anderson MS, Fragiadakis GK, ... ... Hebrok M, et al. Single cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree. Elife. 10. PMID 34009124 DOI: 10.7554/eLife.67776 |
0.393 |
|
| 2020 |
Nair GG, Tzanakakis ES, Hebrok M. Emerging routes to the generation of functional β-cells for diabetes mellitus cell therapy. Nature Reviews. Endocrinology. PMID 32587391 DOI: 10.1038/S41574-020-0375-3 |
0.44 |
|
| 2020 |
Russell R, Carnese PP, Hennings TG, Walker EM, Russ HA, Liu JS, Giacometti S, Stein R, Hebrok M. Loss of the transcription factor MAFB limits β-cell derivation from human PSCs. Nature Communications. 11: 2742. PMID 32488111 DOI: 10.1038/S41467-020-16550-9 |
0.51 |
|
| 2019 |
Zhou X, Nair GG, Russ HA, Belair CD, Li ML, Shveygert M, Hebrok M, Blelloch R. LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State. Stem Cell Reports. PMID 31883920 DOI: 10.1016/J.Stemcr.2019.11.009 |
0.466 |
|
| 2019 |
Tong X, Dai C, Walker JT, Nair GG, Kennedy A, Carr RM, Hebrok M, Powers AC, Stein R. Lipid Droplet Accumulation in Human Pancreatic Islets is Dependent Upon Both Donor Age and Health. Diabetes. PMID 31836690 DOI: 10.2337/Db19-0281 |
0.449 |
|
| 2019 |
Pekrun K, De Alencastro G, Luo QJ, Liu J, Kim Y, Nygaard S, Galivo F, Zhang F, Song R, Tiffany MR, Xu J, Hebrok M, Grompe M, Kay MA. Using a barcoded AAV capsid library to select for clinically relevant gene therapy vectors. Jci Insight. 4. PMID 31723052 DOI: 10.1172/Jci.Insight.131610 |
0.373 |
|
| 2019 |
Jaafar R, Tran S, Shah A, Sun G, Valdearcos M, Marchetti P, Masini M, Swisa A, Giacometti S, Bernal-Mizrachi E, Matveyenko A, Hebrok M, Dor Y, Rutter GA, Koliwad SK, et al. mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes. The Journal of Clinical Investigation. 130. PMID 31265435 DOI: 10.1172/Jci127021 |
0.642 |
|
| 2019 |
Spaeth JM, Liu JH, Peters D, Guo M, Osipovich AB, Mohammadi F, Roy N, Bhushan A, Magnuson MA, Hebrok M, Wright CVE, Stein R. The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function. Diabetes. PMID 31201281 DOI: 10.2337/Db19-0349 |
0.471 |
|
| 2019 |
Nair GG, Liu JS, Russ HA, Tran S, Saxton MS, Chen R, Juang C, Li ML, Nguyen VQ, Giacometti S, Puri S, Xing Y, Wang Y, Szot GL, Oberholzer J, ... ... Hebrok M, et al. Author Correction: Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells. Nature Cell Biology. PMID 30914825 DOI: 10.1038/S41556-019-0316-3 |
0.342 |
|
| 2019 |
Harari N, Sakhneny L, Khalifa-Malka L, Busch A, Hertel KJ, Hebrok M, Landsman L. Pancreatic pericytes originate from the embryonic pancreatic mesenchyme. Developmental Biology. PMID 30771302 DOI: 10.1016/J.Ydbio.2019.01.020 |
0.504 |
|
| 2019 |
Nair GG, Liu JS, Russ HA, Tran S, Saxton MS, Chen R, Juang C, Li ML, Nguyen VQ, Giacometti S, Puri S, Xing Y, Wang Y, Szot GL, Oberholzer J, ... ... Hebrok M, et al. Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells. Nature Cell Biology. 21: 263-274. PMID 30710150 DOI: 10.1038/S41556-018-0271-4 |
0.456 |
|
| 2019 |
Hendley AM, Urano A, Kerper NR, Duong P, Bailey P, Chang DK, Biankin AV, Dawson DW, Kim G, Raffai RL, Hebrok M. Abstract C20: Smpd3 augments chemotherapy and thwarts PDA progression Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C20 |
0.378 |
|
| 2019 |
Nair G, Russ H, Hebrok M. Rapid generation of functional mature pancreatic islet-beta cells from human pluripotent stem cells Protocol Exchange. DOI: 10.1038/Protex.2018.140 |
0.489 |
|
| 2018 |
Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, ... ... Hebrok M, et al. The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis. The Journal of Clinical Investigation. PMID 30010625 DOI: 10.1172/Jci94287 |
0.468 |
|
| 2018 |
Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M. Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges. Cell Stem Cell. 22: 810-823. PMID 29859172 DOI: 10.1016/J.Stem.2018.05.016 |
0.365 |
|
| 2018 |
Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ, Hebrok M, et al. Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca Sensitivity of Insulin Secretion Vesicles. Developmental Cell. PMID 29656931 DOI: 10.1016/J.Devcel.2018.03.013 |
0.392 |
|
| 2018 |
Puri S, Roy N, Russ HA, Leonhardt L, French EK, Roy R, Bengtsson H, Scott DK, Stewart AF, Hebrok M. Replication confers β cell immaturity. Nature Communications. 9: 485. PMID 29396395 DOI: 10.1038/S41467-018-02939-0 |
0.435 |
|
| 2018 |
Faleo G, Ward C, Parent A, Nair G, Chang W, Stock P, Hebrok M, Tang Q. Co-Transplant of Parathyroid Gland and Stem Cell-Derived Insulin-Producing Cells Enhances Graft Survival through Release of Pro-Angiogenic and Pro-Survival Factors Transplantation. 102: S350. DOI: 10.1097/01.Tp.0000543090.13406.2D |
0.334 |
|
| 2017 |
Faleo G, Russ HA, Wisel S, Parent AV, Nguyen V, Nair GG, Freise JE, Villanueva KE, Szot GL, Hebrok M, Tang Q. Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant. Stem Cell Reports. PMID 28803916 DOI: 10.1016/J.Stemcr.2017.07.012 |
0.347 |
|
| 2017 |
Chang R, Faleo G, Russ HA, Parent AV, Elledge SK, Bernards DA, Allen JL, Villanueva K, Hebrok M, Tang Q, Desai TA. Nanoporous Immunoprotective Device for Stem Cell Derived β Cell Replacement Therapy. Acs Nano. PMID 28763191 DOI: 10.1021/Acsnano.7B01239 |
0.382 |
|
| 2017 |
von Figura G, Fahrenkrog-Petersen L, Hidalgo-Sastre A, Hartmann D, Hüser N, Schmid RM, Hebrok M, Roy N, Esposito I. Atypical flat lesions derive from pancreatic acinar cells. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. PMID 28473229 DOI: 10.1016/J.Pan.2017.04.014 |
0.33 |
|
| 2017 |
Ivry SL, Sharib JM, Dominguez DA, Roy N, Hatcher SE, Yip-Schneider M, Schmidt CM, Brand RE, Park WG, Hebrok M, Kim G, O'Donoghue AJ, Kirkwood KS, Craik CS. Global protease activity profiling provides differential diagnosis of pancreatic cysts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28424202 DOI: 10.1158/1078-0432.Ccr-16-2987 |
0.315 |
|
| 2017 |
Liu JS, Hebrok M. All mixed up: defining roles for β-cell subtypes in mature islets. Genes & Development. 31: 228-240. PMID 28270515 DOI: 10.1101/Gad.294389.116 |
0.441 |
|
| 2017 |
Hebrok M. Designing β Cells. Cell Metabolism. 25: 223-224. PMID 28178560 DOI: 10.1016/J.Cmet.2017.01.018 |
0.367 |
|
| 2016 |
Roy N, Takeuchi KK, Ruggeri JM, Bailey P, Chang D, Li J, Leonhardt L, Puri S, Hoffman MT, Gao S, Halbrook CJ, Song Y, Ljungman M, Malik S, Wright CV, ... ... Hebrok M, et al. PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance. Genes & Development. 30: 2669-2683. PMID 28087712 DOI: 10.1101/Gad.291021.116 |
0.484 |
|
| 2016 |
Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA. Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity. Diabetologia. PMID 27785529 DOI: 10.1007/S00125-016-4144-8 |
0.387 |
|
| 2016 |
Muñoz-Bravo JL, Flores-Martínez A, Herrero-Martin G, Puri S, Taketo MM, Rojas A, Hebrok M, Cano DA. Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity. Plos One. 11: e0164714. PMID 27736991 DOI: 10.1371/Journal.Pone.0164714 |
0.472 |
|
| 2016 |
Dorrell C, Schug J, Canaday PS, Russ HA, Tarlow BD, Grompe MT, Horton T, Hebrok M, Streeter PR, Kaestner KH, Grompe M. Human islets contain four distinct subtypes of β cells. Nature Communications. 7: 11756. PMID 27399229 DOI: 10.1038/Ncomms11756 |
0.441 |
|
| 2016 |
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, ... ... Hebrok M, et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. PMID 27089513 DOI: 10.1038/Nm.4082 |
0.428 |
|
| 2016 |
Hendley AM, Wang YJ, Polireddy K, Alsina J, Ahmed I, Lafaro KJ, Zhang H, Roy N, Savidge SG, Cao Y, Hebrok M, Maitra A, Reynolds A, Goggins MG, Younes M, et al. p120 Catenin suppresses basal epithelial cell extrusion in invasive pancreatic neoplasia. Cancer Research. PMID 27032419 DOI: 10.1158/0008-5472.Can-15-2268 |
0.449 |
|
| 2016 |
Wilcox NS, Rui J, Hebrok M, Herold KC. Life and death of β cells in Type 1 diabetes: A comprehensive review. Journal of Autoimmunity. PMID 27017348 DOI: 10.1016/J.Jaut.2016.02.001 |
0.414 |
|
| 2016 |
Zhu S, Russ HA, Wang X, Zhang M, Ma T, Xu T, Tang S, Hebrok M, Ding S. Human pancreatic beta-like cells converted from fibroblasts. Nature Communications. 7: 10080. PMID 26733021 DOI: 10.1038/Ncomms10080 |
0.517 |
|
| 2016 |
Russ HA, Landsman L, Moss CL, Higdon R, Greer RL, Kaihara K, Salamon R, Kolker E, Hebrok M. Dynamic Proteomic Analysis of Pancreatic Mesenchyme Reveals Novel Factors That Enhance Human Embryonic Stem Cell to Pancreatic Cell Differentiation. Stem Cells International. 2016: 6183562. PMID 26681951 DOI: 10.1155/2016/6183562 |
0.511 |
|
| 2015 |
Roy N, Hebrok M. Regulation of Cellular Identity in Cancer. Developmental Cell. 35: 674-84. PMID 26702828 DOI: 10.1016/J.Devcel.2015.12.001 |
0.394 |
|
| 2015 |
Saini C, Petrenko V, Pulimeno P, Giovannoni L, Berney T, Hebrok M, Howald C, Dermitzakis ET, Dibner C. A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells. Diabetes, Obesity & Metabolism. PMID 26662378 DOI: 10.1111/Dom.12616 |
0.379 |
|
| 2015 |
Suriben R, Kaihara KA, Paolino M, Reichelt M, Kummerfeld SK, Modrusan Z, Dugger DL, Newton K, Sagolla M, Webster JD, Liu J, Hebrok M, Dixit VM. β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1. Cell. PMID 26627735 DOI: 10.1016/J.Cell.2015.10.076 |
0.437 |
|
| 2015 |
Zdravkovic T, Nazor KL, Larocque N, Gormley M, Donne M, Hunkapillar N, Giritharan G, Bernstein HS, Wei G, Hebrok M, Zeng X, Genbacev O, Mattis A, McMaster MT, Krtolica A, et al. Human stem cells from single blastomeres reveal pathways of Embryonic or trophoblast fate specification. Development (Cambridge, England). PMID 26483210 DOI: 10.1242/Dev.122846 |
0.395 |
|
| 2015 |
Dhawan S, Tschen SI, Zeng C, Guo T, Hebrok M, Matveyenko A, Bhushan A. DNA methylation directs functional maturation of pancreatic β cells. The Journal of Clinical Investigation. PMID 26098213 DOI: 10.1172/Jci79956 |
0.41 |
|
| 2015 |
Nair G, Hebrok M. Islet formation in mice and men: lessons for the generation of functional insulin-producing β-cells from human pluripotent stem cells. Current Opinion in Genetics & Development. 32: 171-180. PMID 25909383 DOI: 10.1016/J.Gde.2015.03.004 |
0.464 |
|
| 2015 |
Russ HA, Parent AV, Ringler JJ, Hennings TG, Nair GG, Shveygert M, Guo T, Puri S, Haataja L, Cirulli V, Blelloch R, Szot GL, Arvan P, Hebrok M. Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro. The Embo Journal. 34: 1759-72. PMID 25908839 DOI: 10.15252/embj.201591058 |
0.42 |
|
| 2015 |
Roy N, Malik S, Villanueva KE, Urano A, Lu X, Von Figura G, Seeley ES, Dawson DW, Collisson EA, Hebrok M. Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation. Genes & Development. 29: 658-71. PMID 25792600 DOI: 10.1101/Gad.256628.114 |
0.475 |
|
| 2015 |
Huskey NE, Guo T, Evason KJ, Momcilovic O, Pardo D, Creasman KJ, Judson RL, Blelloch R, Oakes SA, Hebrok M, Goga A. CDK1 inhibition targets the p53-NOXA-MCL1 axis, selectively kills embryonic stem cells, and prevents teratoma formation. Stem Cell Reports. 4: 374-89. PMID 25733019 DOI: 10.1016/J.Stemcr.2015.01.019 |
0.379 |
|
| 2015 |
Chen NM, Singh G, Koenig A, Liou GY, Storz P, Zhang JS, Regul L, Nagarajan S, Kühnemuth B, Johnsen SA, Hebrok M, Siveke J, Billadeau DD, Ellenrieder V, Hessmann E. NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas. Gastroenterology. 148: 1024-1034.e9. PMID 25623042 DOI: 10.1053/J.Gastro.2015.01.033 |
0.397 |
|
| 2015 |
Singh SK, Chen NM, Hessmann E, Siveke J, Lahmann M, Singh G, Voelker N, Vogt S, Esposito I, Schmidt A, Brendel C, Stiewe T, Gaedcke J, Mernberger M, Crawford HC, ... ... Hebrok M, et al. Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity. The Embo Journal. 34: 517-30. PMID 25586376 DOI: 10.15252/Embj.201489574 |
0.487 |
|
| 2015 |
Puri S, Folias AE, Hebrok M. Plasticity and dedifferentiation within the pancreas: development, homeostasis, and disease. Cell Stem Cell. 16: 18-31. PMID 25465113 DOI: 10.1016/J.Stem.2014.11.001 |
0.351 |
|
| 2014 |
Russ HA, Hebrok M. Taming the young and restless--epigenetic gene regulation in pancreas and beta-cell precursors. The Embo Journal. 33: 2135-6. PMID 25154606 DOI: 10.15252/Embj.201489751 |
0.482 |
|
| 2014 |
Folias AE, Penaranda C, Su AL, Bluestone JA, Hebrok M. Aberrant innate immune activation following tissue injury impairs pancreatic regeneration. Plos One. 9: e102125. PMID 25010227 DOI: 10.1371/Journal.Pone.0102125 |
0.403 |
|
| 2014 |
Morris JP, Greer R, Russ HA, von Figura G, Kim GE, Busch A, Lee J, Hertel KJ, Kim S, McManus M, Hebrok M. Dicer regulates differentiation and viability during mouse pancreatic cancer initiation. Plos One. 9: e95486. PMID 24788257 DOI: 10.1371/Journal.Pone.0095486 |
0.302 |
|
| 2014 |
Folias AE, Hebrok M. Diabetes. Solving human β-cell development--what does the mouse say? Nature Reviews. Endocrinology. 10: 253-5. PMID 24566816 DOI: 10.1038/Nrendo.2014.18 |
0.395 |
|
| 2014 |
von Figura G, Fukuda A, Roy N, Liku ME, Morris Iv JP, Kim GE, Russ HA, Firpo MA, Mulvihill SJ, Dawson DW, Ferrer J, Mueller WF, Busch A, Hertel KJ, Hebrok M. The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma. Nature Cell Biology. 16: 255-67. PMID 24561622 DOI: 10.1038/Ncb2916 |
0.432 |
|
| 2014 |
Li K, Zhu S, Russ HA, Xu S, Xu T, Zhang Y, Ma T, Hebrok M, Ding S. Small molecules facilitate the reprogramming of mouse fibroblasts into pancreatic lineages. Cell Stem Cell. 14: 228-36. PMID 24506886 DOI: 10.1016/J.Stem.2014.01.006 |
0.497 |
|
| 2014 |
von Figura G, Morris JP, Wright CV, Hebrok M. Nr5a2 maintains acinar cell differentiation and constrains oncogenic Kras-mediated pancreatic neoplastic initiation. Gut. 63: 656-64. PMID 23645620 DOI: 10.1136/Gutjnl-2012-304287 |
0.492 |
|
| 2014 |
Russ HA, Hebrok M. Taming the young and restless - Epigenetic gene regulation in pancreas and beta-cell precursors Embo Journal. 33: 2135-2136. DOI: 10.15252/embj.20148975 |
0.32 |
|
| 2014 |
Hebrok M. Analyzing pancreas development with the goal to generate functional ß-cells from stem cells and prevent neoplastic transformation Pancreatology. 14. DOI: 10.1016/J.Pan.2014.03.018 |
0.387 |
|
| 2013 |
Puri S, Akiyama H, Hebrok M. VHL-mediated disruption of Sox9 activity compromises β-cell identity and results in diabetes mellitus. Genes & Development. 27: 2563-75. PMID 24298056 DOI: 10.1101/Gad.227785.113 |
0.468 |
|
| 2013 |
Puri S, GarcÃa-Núñez A, Hebrok M, Cano DA. Elimination of von Hippel-Lindau function perturbs pancreas endocrine homeostasis in mice. Plos One. 8: e72213. PMID 23977255 DOI: 10.1371/Journal.Pone.0072213 |
0.466 |
|
| 2013 |
Greer RL, Staley BK, Liou A, Hebrok M. Numb regulates acinar cell dedifferentiation and survival during pancreatic damage and acinar-to-ductal metaplasia. Gastroenterology. 145: 1088-1097.e8. PMID 23891977 DOI: 10.1053/J.Gastro.2013.07.027 |
0.452 |
|
| 2013 |
Zhang Y, Morris JP, Yan W, Schofield HK, Gurney A, Simeone DM, Millar SE, Hoey T, Hebrok M, Pasca di Magliano M. Canonical wnt signaling is required for pancreatic carcinogenesis. Cancer Research. 73: 4909-22. PMID 23761328 DOI: 10.1158/0008-5472.Can-12-4384 |
0.492 |
|
| 2013 |
Parent AV, Russ HA, Khan IS, LaFlam TN, Metzger TC, Anderson MS, Hebrok M. Generation of functional thymic epithelium from human embryonic stem cells that supports host T cell development. Cell Stem Cell. 13: 219-29. PMID 23684540 DOI: 10.1016/J.Stem.2013.04.004 |
0.413 |
|
| 2013 |
Stanger BZ, Hebrok M. Control of cell identity in pancreas development and regeneration. Gastroenterology. 144: 1170-9. PMID 23622126 DOI: 10.1053/J.Gastro.2013.01.074 |
0.426 |
|
| 2013 |
Lin WC, Rajbhandari N, Liu C, Sakamoto K, Zhang Q, Triplett AA, Batra SK, Opavsky R, Felsher DW, DiMaio DJ, Hollingsworth MA, Morris JP, Hebrok M, Witkiewicz AK, Brody JR, et al. Dormant cancer cells contribute to residual disease in a model of reversible pancreatic cancer. Cancer Research. 73: 1821-30. PMID 23467612 DOI: 10.1158/0008-5472.Can-12-2067 |
0.425 |
|
| 2013 |
Guo T, Landsman L, Li N, Hebrok M. Factors expressed by murine embryonic pancreatic mesenchyme enhance generation of insulin-producing cells from hESCs. Diabetes. 62: 1581-92. PMID 23305648 DOI: 10.2337/Db12-0167 |
0.516 |
|
| 2013 |
Pasca di Magliano M, Forsmark C, Freedman S, Hebrok M, Pasricha PJ, Saluja A, Stanger BZ, Holt J, Serrano J, James SP, Rustgi AK. Advances in acute and chronic pancreatitis: from development to inflammation and repair. Gastroenterology. 144: e1-4. PMID 23159450 DOI: 10.1053/J.Gastro.2012.11.018 |
0.321 |
|
| 2012 |
Kopp JL, von Figura G, Mayes E, Liu FF, Dubois CL, Morris JP, Pan FC, Akiyama H, Wright CV, Jensen K, Hebrok M, Sander M. Identification of Sox9-dependent acinar-to-ductal reprogramming as the principal mechanism for initiation of pancreatic ductal adenocarcinoma. Cancer Cell. 22: 737-50. PMID 23201164 DOI: 10.1016/J.Ccr.2012.10.025 |
0.447 |
|
| 2012 |
Puri S, Hebrok M. Diabetic β Cells: To Be or Not To Be? Cell. 150: 1103-4. PMID 22980973 DOI: 10.1016/J.Cell.2012.08.021 |
0.366 |
|
| 2012 |
Hebrok M. Generating β cells from stem cells-the story so far. Cold Spring Harbor Perspectives in Medicine. 2: a007674. PMID 22675664 DOI: 10.1101/Cshperspect.A007674 |
0.413 |
|
| 2012 |
Fukuda A, Morris JP, Hebrok M. Bmi1 is required for regeneration of the exocrine pancreas in mice. Gastroenterology. 143: 821-31.e1-2. PMID 22609312 DOI: 10.1053/J.Gastro.2012.05.009 |
0.428 |
|
| 2012 |
Qin H, Blaschke K, Wei G, Ohi Y, Blouin L, Qi Z, Yu J, Yeh RF, Hebrok M, Ramalho-Santos M. Transcriptional analysis of pluripotency reveals the Hippo pathway as a barrier to reprogramming. Human Molecular Genetics. 21: 2054-67. PMID 22286172 DOI: 10.1093/Hmg/Dds023 |
0.441 |
|
| 2012 |
Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop? The notion of homicide or β-cell suicide revisited (Diabetes (2011) 60, (1370-1379)) Diabetes. 61: 1648. DOI: 10.2337/Db12-Er06A |
0.338 |
|
| 2012 |
Lin W, Rajbhandari N, Liu C, Sakamoto K, Batra S, Opavsky R, Felsher D, Hollingsworth M, Hebrok M, Rui H, Wagner K. Abstract LB-429: Dormant cancer cells contribute to residual disease in a mouse model for reversible pancreatic cancer Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-429 |
0.395 |
|
| 2011 |
Landsman L, Parent A, Hebrok M. Elevated Hedgehog/Gli signaling causes beta-cell dedifferentiation in mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 17010-5. PMID 21969560 DOI: 10.1073/Pnas.1105404108 |
0.523 |
|
| 2011 |
Landsman L, Nijagal A, Whitchurch TJ, Vanderlaan RL, Zimmer WE, Mackenzie TC, Hebrok M. Pancreatic mesenchyme regulates epithelial organogenesis throughout development. Plos Biology. 9: e1001143. PMID 21909240 DOI: 10.1371/Journal.Pbio.1001143 |
0.529 |
|
| 2011 |
Atkinson MA, Bluestone JA, Eisenbarth GS, Hebrok M, Herold KC, Accili D, Pietropaolo M, Arvan PR, Von Herrath M, Markel DS, Rhodes CJ. How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited. Diabetes. 60: 1370-9. PMID 21525508 DOI: 10.2337/Db10-1797 |
0.38 |
|
| 2011 |
Ohi Y, Qin H, Hong C, Blouin L, Polo JM, Guo T, Qi Z, Downey SL, Manos PD, Rossi DJ, Yu J, Hebrok M, Hochedlinger K, Costello JF, Song JS, et al. Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells. Nature Cell Biology. 13: 541-9. PMID 21499256 DOI: 10.1038/Ncb2239 |
0.36 |
|
| 2011 |
Fukuda A, Wang SC, Morris JP, Folias AE, Liou A, Kim GE, Akira S, Boucher KM, Firpo MA, Mulvihill SJ, Hebrok M. Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression. Cancer Cell. 19: 441-55. PMID 21481787 DOI: 10.1016/J.Ccr.2011.03.002 |
0.384 |
|
| 2010 |
Morris JP, Wang SC, Hebrok M. KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. Nature Reviews. Cancer. 10: 683-95. PMID 20814421 DOI: 10.1038/Nrc2899 |
0.497 |
|
| 2010 |
Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N. Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling. Plos Genetics. 6: e1000990. PMID 20585550 DOI: 10.1371/Journal.Pgen.1000990 |
0.394 |
|
| 2010 |
Cervantes S, Lau J, Cano DA, Borromeo-Austin C, Hebrok M. Primary cilia regulate Gli/Hedgehog activation in pancreas. Proceedings of the National Academy of Sciences of the United States of America. 107: 10109-14. PMID 20479231 DOI: 10.1073/Pnas.0909900107 |
0.469 |
|
| 2010 |
Puri S, Hebrok M. Cellular plasticity within the pancreas--lessons learned from development. Developmental Cell. 18: 342-56. PMID 20230744 DOI: 10.1016/J.Devcel.2010.02.005 |
0.377 |
|
| 2010 |
Lau J, Hebrok M. Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function. Diabetes. 59: 1211-21. PMID 20185815 DOI: 10.2337/Db09-0914 |
0.536 |
|
| 2010 |
Morris JP, Cano DA, Sekine S, Wang SC, Hebrok M. Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice. The Journal of Clinical Investigation. 120: 508-20. PMID 20071774 DOI: 10.1172/Jci40045 |
0.534 |
|
| 2010 |
Wang SC, Fukuda A, Morris JP, Liou A, Akira S, Hebrok M. Stat3 and MMP7 mediate multiple aspects of pancreatic ductal adenocarcinoma biology Journal of the American College of Surgeons. 211. DOI: 10.1016/J.Jamcollsurg.2010.06.318 |
0.321 |
|
| 2009 |
Morris JP, Hebrok M. It's a free for all--insulin-positive cells join the group of potential progenitors for pancreatic ductal adenocarcinoma. Cancer Cell. 16: 359-61. PMID 19878864 DOI: 10.1016/J.Ccr.2009.10.006 |
0.454 |
|
| 2009 |
Sekine S, Ogawa R, Mcmanus MT, Kanai Y, Hebrok M. Dicer is required for proper liver zonation. The Journal of Pathology. 219: 365-72. PMID 19718708 DOI: 10.1002/Path.2606 |
0.353 |
|
| 2009 |
Guo T, Hebrok M. Stem cells to pancreatic beta-cells: new sources for diabetes cell therapy. Endocrine Reviews. 30: 214-27. PMID 19389995 DOI: 10.1210/Er.2009-0004 |
0.477 |
|
| 2009 |
Sekine S, Ogawa R, Ito R, Hiraoka N, McManus MT, Kanai Y, Hebrok M. Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis. Gastroenterology. 136: 2304-2315.e1-4. PMID 19272382 DOI: 10.1053/J.Gastro.2009.02.067 |
0.317 |
|
| 2009 |
Nolan-Stevaux O, Lau J, Truitt ML, Chu GC, Hebrok M, Fernández-Zapico ME, Hanahan D. GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation. Genes & Development. 23: 24-36. PMID 19136624 DOI: 10.1101/Gad.1753809 |
0.532 |
|
| 2009 |
Cervantes S, Yamaguchi TP, Hebrok M. Wnt5a is essential for intestinal elongation in mice. Developmental Biology. 326: 285-94. PMID 19100728 DOI: 10.1016/J.Ydbio.2008.11.020 |
0.35 |
|
| 2009 |
Puri S, Cano DA, Hebrok M. A role for von Hippel-Lindau protein in pancreatic beta-cell function. Diabetes. 58: 433-41. PMID 19033400 DOI: 10.2337/Db08-0749 |
0.488 |
|
| 2008 |
Heiser PW, Cano DA, Landsman L, Kim GE, Kench JG, Klimstra DS, Taketo MM, Biankin AV, Hebrok M. Stabilization of beta-catenin induces pancreas tumor formation. Gastroenterology. 135: 1288-300. PMID 18725219 DOI: 10.1053/J.Gastro.2008.06.089 |
0.761 |
|
| 2008 |
Bluestone JA, Hebrok M. Safer, longer-lasting regulatory T cells with beta-catenin. Nature Medicine. 14: 118-9. PMID 18256611 DOI: 10.1038/Nm0208-118 |
0.392 |
|
| 2008 |
Cano DA, Rulifson IC, Heiser PW, Swigart LB, Pelengaris S, German M, Evan GI, Bluestone JA, Hebrok M. Regulated beta-cell regeneration in the adult mouse pancreas. Diabetes. 57: 958-66. PMID 18083786 DOI: 10.2337/Db07-0913 |
0.76 |
|
| 2007 |
Burris RE, Hebrok M. Pancreatic innervation in mouse development and beta-cell regeneration. Neuroscience. 150: 592-602. PMID 18006238 DOI: 10.1016/J.Neuroscience.2007.09.079 |
0.767 |
|
| 2007 |
Regard JB, Kataoka H, Cano DA, Camerer E, Yin L, Zheng YW, Scanlan TS, Hebrok M, Coughlin SR. Probing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion. The Journal of Clinical Investigation. 117: 4034-43. PMID 17992256 DOI: 10.1172/Jci32994 |
0.381 |
|
| 2007 |
Pasca di Magliano M, Biankin AV, Heiser PW, Cano DA, Gutierrez PJ, Deramaudt T, Segara D, Dawson AC, Kench JG, Henshall SM, Sutherland RL, Dlugosz A, Rustgi AK, Hebrok M. Common activation of canonical Wnt signaling in pancreatic adenocarcinoma. Plos One. 2: e1155. PMID 17982507 DOI: 10.1371/Journal.Pone.0001155 |
0.763 |
|
| 2007 |
Nawroth R, van Zante A, Cervantes S, McManus M, Hebrok M, Rosen SD. Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells. Plos One. 2: e392. PMID 17460759 DOI: 10.1371/Journal.Pone.0000392 |
0.508 |
|
| 2007 |
Puri S, Hebrok M. Dynamics of embryonic pancreas development using real-time imaging. Developmental Biology. 306: 82-93. PMID 17448459 DOI: 10.1016/J.Ydbio.2007.03.003 |
0.437 |
|
| 2007 |
Robbins DJ, Hebrok M. Hedgehogs: la dolce vita. Workshop on Hedgehog-Gli Signaling in Cancer and Stem Cells. Embo Reports. 8: 451-5. PMID 17431408 DOI: 10.1038/Sj.Embor.7400959 |
0.372 |
|
| 2007 |
Rulifson IC, Karnik SK, Heiser PW, ten Berge D, Chen H, Gu X, Taketo MM, Nusse R, Hebrok M, Kim SK. Wnt signaling regulates pancreatic beta cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 104: 6247-52. PMID 17404238 DOI: 10.1073/Pnas.0701509104 |
0.782 |
|
| 2007 |
Morton JP, Mongeau ME, Klimstra DS, Morris JP, Lee YC, Kawaguchi Y, Wright CV, Hebrok M, Lewis BC. Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 5103-8. PMID 17372229 DOI: 10.1073/Pnas.0701158104 |
0.482 |
|
| 2007 |
Cano DA, Hebrok M, Zenker M. Pancreatic development and disease. Gastroenterology. 132: 745-62. PMID 17258745 DOI: 10.1053/J.Gastro.2006.12.054 |
0.372 |
|
| 2007 |
Sekine S, Gutiérrez PJ, Lan BY, Feng S, Hebrok M. Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomy. Hepatology (Baltimore, Md.). 45: 361-8. PMID 17256747 DOI: 10.1002/Hep.21523 |
0.425 |
|
| 2007 |
Cervantes S, Yamaguchi TP, Hebrok M. A non-canonical Wnt pathway mediated by Wnt5a is required for midgut elongation Developmental Biology. 306: 419-420. DOI: 10.1016/J.Ydbio.2007.03.651 |
0.324 |
|
| 2007 |
Burris RE, Hebrok M. Autonomic and sensory pancreatic nerves are differentially affected by large-scale β-cell turnover in the RIP-cmycER mouse Developmental Biology. 306: 444. DOI: 10.1016/J.Ydbio.2007.03.503 |
0.737 |
|
| 2006 |
Cano DA, Sekine S, Hebrok M. Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis. Gastroenterology. 131: 1856-69. PMID 17123526 DOI: 10.1053/J.Gastro.2006.10.050 |
0.512 |
|
| 2006 |
Pasca di Magliano M, Sekine S, Ermilov A, Ferris J, Dlugosz AA, Hebrok M. Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes & Development. 20: 3161-73. PMID 17114586 DOI: 10.1101/Gad.1470806 |
0.453 |
|
| 2006 |
Heiser PW, Lau J, Taketo MM, Herrera PL, Hebrok M. Stabilization of beta-catenin impacts pancreas growth. Development (Cambridge, England). 133: 2023-32. PMID 16611688 DOI: 10.1242/Dev.02366 |
0.763 |
|
| 2006 |
Sekine S, Lan BY, Bedolli M, Feng S, Hebrok M. Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in mice. Hepatology (Baltimore, Md.). 43: 817-25. PMID 16557553 DOI: 10.1002/Hep.21131 |
0.373 |
|
| 2006 |
Lau J, Kawahira H, Hebrok M. Hedgehog signaling in pancreas development and disease. Cellular and Molecular Life Sciences : Cmls. 63: 642-52. PMID 16465449 DOI: 10.1007/S00018-005-5357-Z |
0.503 |
|
| 2005 |
Kawahira H, Scheel DW, Smith SB, German MS, Hebrok M. Hedgehog signaling regulates expansion of pancreatic epithelial cells. Developmental Biology. 280: 111-21. PMID 15766752 DOI: 10.1016/J.Ydbio.2005.01.008 |
0.467 |
|
| 2005 |
Perez SE, Cano DA, Dao-Pick T, Rougier JP, Werb Z, Hebrok M. Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo. Diabetes. 54: 694-701. PMID 15734845 DOI: 10.2337/Diabetes.54.3.694 |
0.327 |
|
| 2004 |
Cano DA, Murcia NS, Pazour GJ, Hebrok M. Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization. Development (Cambridge, England). 131: 3457-67. PMID 15226261 DOI: 10.1242/Dev.01189 |
0.471 |
|
| 2004 |
Hebrok M, Reichardt LF. Brain meets pancreas: netrin, an axon guidance molecule, controls epithelial cell migration. Trends in Cell Biology. 14: 153-5. PMID 15134068 DOI: 10.1016/J.Tcb.2004.02.005 |
0.4 |
|
| 2004 |
Heiser PW, Hebrok M. Development and cancer: lessons learned in the pancreas. Cell Cycle (Georgetown, Tex.). 3: 270-2. PMID 14726662 DOI: 10.4161/Cc.3.3.731 |
0.743 |
|
| 2003 |
Pasca di Magliano M, Hebrok M. Hedgehog signalling in cancer formation and maintenance. Nature Reviews. Cancer. 3: 903-11. PMID 14737121 DOI: 10.1038/Nrc1229 |
0.413 |
|
| 2003 |
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernández-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL, Hebrok M. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature. 425: 851-6. PMID 14520413 DOI: 10.1038/Nature02009 |
0.769 |
|
| 2003 |
Kawahira H, Ma NH, Tzanakakis ES, McMahon AP, Chuang PT, Hebrok M. Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development (Cambridge, England). 130: 4871-9. PMID 12917290 DOI: 10.1242/Dev.00653 |
0.502 |
|
| 2003 |
Hebrok M. Hedgehog signaling in pancreas development. Mechanisms of Development. 120: 45-57. PMID 12490295 DOI: 10.1016/S0925-4773(02)00331-3 |
0.466 |
|
| 2001 |
Kim SK, Hebrok M. Intercellular signals regulating pancreas development and function. Genes & Development. 15: 111-27. PMID 11157769 DOI: 10.1101/Gad.859401 |
0.375 |
|
| 2000 |
Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA. Regulation of pancreas development by hedgehog signaling. Development (Cambridge, England). 127: 4905-13. PMID 11044404 |
0.637 |
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| 2000 |
Kim SK, Hebrok M, Li E, Oh SP, Schrewe H, Harmon EB, Lee JS, Melton DA. Activin receptor patterning of foregut organogenesis. Genes & Development. 14: 1866-71. PMID 10921901 DOI: 10.1101/Gad.14.15.1866 |
0.594 |
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| 1999 |
Hebrok M, Kim SK, Melton DA. Screening for novel pancreatic genes expressed during embryogenesis. Diabetes. 48: 1550-6. PMID 10426372 DOI: 10.2337/Diabetes.48.8.1550 |
0.52 |
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| 1998 |
Hebrok M, Kim SK, Melton DA. Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes & Development. 12: 1705-13. PMID 9620856 DOI: 10.1101/Gad.12.11.1705 |
0.633 |
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| 1997 |
Kim SK, Hebrok M, Melton DA. Pancreas development in the chick embryo. Cold Spring Harbor Symposia On Quantitative Biology. 62: 377-83. PMID 9598372 DOI: 10.1101/Sqb.1997.062.01.045 |
0.522 |
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| 1997 |
Kim SK, Hebrok M, Melton DA. Notochord to endoderm signaling is required for pancreas development. Development (Cambridge, England). 124: 4243-52. PMID 9334273 |
0.599 |
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| 1995 |
Rohwedel J, Horák V, Hebrok M, Füchtbauer EM, Wobus AM. M-twist expression inhibits mouse embryonic stem cell-derived myogenic differentiation in vitro. Experimental Cell Research. 220: 92-100. PMID 7664846 DOI: 10.1006/Excr.1995.1295 |
0.361 |
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| 1994 |
Hebrok M, Wertz K, Füchtbauer EM. M-twist is an inhibitor of muscle differentiation. Developmental Biology. 165: 537-44. PMID 7958419 DOI: 10.1006/Dbio.1994.1273 |
0.302 |
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