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Margaret Billingsley - Publications

Affiliations: 
2018- Bioengineering University of Pennsylvania, Philadelphia, PA, United States 
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Patel SK, Billingsley MM, Mukalel AJ, Thatte AS, Hamilton AG, Gong N, El-Mayta R, Safford HC, Merolle M, Mitchell MJ. Bile acid-containing lipid nanoparticles enhance extrahepatic mRNA delivery. Theranostics. 14: 1-16. PMID 38164140 DOI: 10.7150/thno.89913  0.619
2023 Billingsley MM, Gong N, Mukalel AJ, Thatte AS, El-Mayta R, Patel SK, Metzloff AE, Swingle KL, Han X, Xue L, Hamilton AG, Safford HC, Alameh MG, Papp TE, Parhiz H, et al. In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism. Small (Weinheim An Der Bergstrasse, Germany). e2304378. PMID 38072809 DOI: 10.1002/smll.202304378  0.639
2023 Thatte AS, Hamilton AG, Nachod BE, Mukalel AJ, Billingsley MM, Palanki R, Swingle KL, Mitchell MJ. mRNA Lipid Nanoparticles for Engineering of Immunosuppressive T Cells for Autoimmunity Therapies. Nano Letters. PMID 37906000 DOI: 10.1021/acs.nanolett.3c02573  0.704
2023 Gong N, Han X, Xue L, El-Mayta R, Metzloff AE, Billingsley MM, Hamilton AG, Mitchell MJ. In situ PEGylation of CAR T cells alleviates cytokine release syndrome and neurotoxicity. Nature Materials. PMID 37696939 DOI: 10.1038/s41563-023-01646-6  0.518
2023 Hamilton AG, Swingle KL, Joseph RA, Mai D, Gong N, Billingsley MM, Alameh MG, Weissman D, Sheppard NC, June CH, Mitchell MJ. Lonizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering. Advanced Healthcare Materials. e2301515. PMID 37602495 DOI: 10.1002/adhm.202301515  0.594
2023 Safford HC, Swingle KL, Geisler HC, Hamilton AG, Thatte AS, Ghalsasi AA, Billingsley MM, Alameh MG, Weissman D, Mitchell MJ. Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta. Small (Weinheim An Der Bergstrasse, Germany). e2303568. PMID 37537704 DOI: 10.1002/smll.202303568  0.621
2023 Palanki R, Bose SK, Dave A, White BM, Berkowitz C, Luks V, Yaqoob F, Han E, Swingle KL, Menon P, Hodgson E, Biswas A, Billingsley MM, Li L, Yiping F, et al. Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease. Acs Nano. PMID 37458484 DOI: 10.1021/acsnano.3c02268  0.548
2023 Haley RM, Chan A, Billingsley MM, Gong N, Padilla MS, Kim EH, Wang H, Yin D, Wangensteen KJ, Tsourkas A, Mitchell MJ. Lipid Nanoparticle Delivery of Small Proteins for Potent RAS Inhibition. Acs Applied Materials & Interfaces. PMID 37115558 DOI: 10.1021/acsami.3c01501  0.509
2023 Swingle KL, Safford HC, Geisler HC, Hamilton AG, Thatte AS, Billingsley MM, Joseph RA, Mrksich K, Padilla MS, Ghalsasi AA, Alameh MG, Weissman D, Mitchell MJ. Ionizable Lipid Nanoparticles for mRNA Delivery to the Placenta during Pregnancy. Journal of the American Chemical Society. PMID 36789893 DOI: 10.1021/jacs.2c12893  0.592
2023 El-Mayta R, Padilla MS, Billingsley MM, Han X, Mitchell MJ. Testing the In Vitro and In Vivo Efficiency of mRNA-Lipid Nanoparticles Formulated by Microfluidic Mixing. Journal of Visualized Experiments : Jove. PMID 36744791 DOI: 10.3791/64810  0.587
2023 Han X, Gong N, Xue L, Billingsley MM, El-Mayta R, Shepherd SJ, Alameh MG, Weissman D, Mitchell MJ. Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis. Nature Communications. 14: 75. PMID 36650129 DOI: 10.1038/s41467-022-35637-z  0.743
2022 Patel SK, Billingsley MM, Frazee C, Han X, Swingle KL, Qin J, Alameh MG, Wang K, Weissman D, Mitchell MJ. Hydroxycholesterol substitution in Ionizable lipid nanoparticles for mRNA delivery to T cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 35569584 DOI: 10.1016/j.jconrel.2022.05.020  0.671
2022 Metzloff AE, Billingsley MM, Mitchell MJ. Lighting the way to personalized mRNA immune cell therapies. Science Advances. 8: eabo2423. PMID 35196095 DOI: 10.1126/sciadv.abo2423  0.541
2021 Swingle KL, Billingsley MM, Bose SK, White B, Palanki R, Dave A, Patel SK, Gong N, Hamilton AG, Alameh MG, Weissman D, Peranteau WH, Mitchell MJ. Amniotic fluid stabilized lipid nanoparticles for in utero intra-amniotic mRNA delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 34742747 DOI: 10.1016/j.jconrel.2021.10.031  0.6
2021 Billingsley MM, Hamilton AG, Mai D, Patel SK, Swingle KL, Sheppard NC, June CH, Mitchell MJ. Orthogonal Design of Experiments for Optimization of Lipid Nanoparticles for mRNA Engineering of CAR T Cells. Nano Letters. PMID 34669421 DOI: 10.1021/acs.nanolett.1c02503  0.651
2021 Zhang D, Atochina-Vasserman EN, Maurya DS, Huang N, Xiao Q, Ona N, Liu M, Shahnawaz H, Ni H, Kim K, Billingsley MM, Pochan DJ, Mitchell MJ, Weissman D, Percec V. One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA. Journal of the American Chemical Society. PMID 34324336 DOI: 10.1021/jacs.1c05813  0.601
2021 Atsavapranee ES, Billingsley MM, Mitchell MJ. Delivery technologies for T cell gene editing: Applications in cancer immunotherapy. Ebiomedicine. 67: 103354. PMID 33910123 DOI: 10.1016/j.ebiom.2021.103354  0.545
2021 Riley RS, Kashyap MV, Billingsley MM, White B, Alameh MG, Bose SK, Zoltick PW, Li H, Zhang R, Cheng AY, Weissman D, Peranteau WH, Mitchell MJ. Ionizable lipid nanoparticles for in utero mRNA delivery. Science Advances. 7. PMID 33523869 DOI: 10.1126/sciadv.aba1028  0.775
2021 Gong N, Sheppard NC, Billingsley MM, June CH, Mitchell MJ. Nanomaterials for T-cell cancer immunotherapy. Nature Nanotechnology. 16: 25-36. PMID 33437036 DOI: 10.1038/s41565-020-00822-y  0.528
2021 Zhang R, El-Mayta R, Murdoch TJ, Warzecha CC, Billingsley MM, Shepherd SJ, Gong N, Wang L, Wilson JM, Lee D, Mitchell MJ. Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liver. Biomaterials Science. PMID 33404020 DOI: 10.1039/d0bm01609h  0.76
2020 Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R. Engineering precision nanoparticles for drug delivery. Nature Reviews. Drug Discovery. PMID 33277608 DOI: 10.1038/s41573-020-0090-8  0.63
2020 Billingsley M, Singh N, Ravikumar P, Zhang R, June CH, Mitchell MJ. Ionizable Lipid Nanoparticle Mediated mRNA Delivery for Human CAR T Cell Engineering. Nano Letters. PMID 31951421 DOI: 10.1021/Acs.Nanolett.9B04246  0.648
2020 Kashyap MV, Riley RS, Billingsley MM, White BM, Butt ZP, Mitchell MJ, Peranteau WH. Ionizable Lipid Nanoparticle Platforms for in Utero Drug Delivery Journal of the American College of Surgeons. 231: S204. DOI: 10.1016/J.JAMCOLLSURG.2020.07.757  0.714
2020 El‐Mayta R, Zhang R, Shepherd SJ, Wang F, Billingsley MM, Dudkin V, Klein D, Lu HD, Mitchell MJ. A Nanoparticle Platform for Accelerated In Vivo Oral Delivery Screening of Nucleic Acids Advanced Therapeutics. 4: 2000111. DOI: 10.1002/adtp.202000111  0.708
2019 Guimaraes PP, Zhang R, Spektor R, Tan M, Chung A, Billingsley MM, El-Mayta R, Riley RS, Wang L, Wilson JM, Mitchell MJ. Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31678653 DOI: 10.1016/J.Jconrel.2019.10.028  0.764
2018 Zhang R, Billingsley MM, Mitchell MJ. Biomaterials for vaccine-based cancer immunotherapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30312721 DOI: 10.1016/J.Jconrel.2018.10.008  0.481
2018 Riley RS, Dang MN, Billingsley MM, Abraham B, Gundlach L, Day ES. Evaluating the Mechanisms of Light-Triggered siRNA Release from Nanoshells for Temporal Control Over Gene Regulation. Nano Letters. PMID 29701993 DOI: 10.1021/Acs.Nanolett.8B00681  0.695
2017 Billingsley MM, Riley RS, Day ES. Antibody-nanoparticle conjugates to enhance the sensitivity of ELISA-based detection methods. Plos One. 12: e0177592. PMID 28494030 DOI: 10.1371/Journal.Pone.0177592  0.655
2017 Melamed JR, Riley RS, Valcourt DM, Billingsley MM, Kreuzberger NL, Day ES. Quantification of siRNA Duplexes Bound to Gold Nanoparticle Surfaces. Methods in Molecular Biology (Clifton, N.J.). 1570: 1-15. PMID 28238126 DOI: 10.1007/978-1-4939-6840-4_1  0.728
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