Koko Ishizuka, M.D., Ph.D. - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Neuropsychiatric diseases and brain development
Website:
http://www.hopkinsmedicine.org/psychiatry/expert_team/faculty/I/Ishizuka.html

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jensen KM, Calhoun VD, Fu Z, Yang K, Faria AV, Ishizuka K, Sawa A, Andrés-Camazón P, Coffman BA, Seebold D, Turner JA, Salisbury DF, Iraji A. A whole-brain neuromark resting-state fMRI analysis of first-episode and early psychosis: Evidence of aberrant cortical-subcortical-cerebellar functional circuitry. Neuroimage. Clinical. 41: 103584. PMID 38422833 DOI: 10.1016/j.nicl.2024.103584  0.468
2024 Yang K, Hasegawa Y, Bhattarai JP, Hua J, Dower M, Etyemez S, Prasad N, Duvall L, Paez A, Smith A, Wang Y, Zhang YF, Lane AP, Ishizuka K, Kamath V, et al. Inflammation-related pathology in the olfactory epithelium: its impact on the olfactory system in psychotic disorders. Molecular Psychiatry. PMID 38321120 DOI: 10.1038/s41380-024-02425-8  0.678
2023 Mihaljevic M, Lam M, Ayala-Grosso C, Davis-Batt F, Schretlen DJ, Ishizuka K, Yang K, Sawa A. Olfactory neuronal cells as a promising tool to realize the "druggable genome" approach for drug discovery in neuropsychiatric disorders. Frontiers in Neuroscience. 16: 1081124. PMID 36967982 DOI: 10.3389/fnins.2022.1081124  0.476
2022 Namkung H, Yukitake H, Fukudome D, Lee BJ, Tian M, Ursini G, Saito A, Lam S, Kannan S, Srivastava R, Niwa M, Sharma K, Zandi P, Jaaro-Peled H, Ishizuka K, et al. The miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder. Neuron. PMID 36379214 DOI: 10.1016/j.neuron.2022.10.031  0.784
2022 Yang K, Hasegawa Y, Hua J, Dower M, Etyemez S, Prasad N, Duvall L, Paez A, Smith A, Lane AP, Ishizuka K, Kamath V, Kamiya A, Sawa A. Immune-related molecular changes in the olfactory epithelium, structural alteration in the olfactory bulb, and psychosis. Biorxiv : the Preprint Server For Biology. PMID 36203543 DOI: 10.1101/2022.09.23.509224  0.651
2022 Kondo M, Norris A, Yang K, Cheshire M, Newkirk I, Chen X, Ishizuka K, Jaffe AE, Sawa A, Pevsner J. Dysfunction of mitochondria and GABAergic interneurons in the anterior cingulate cortex of individuals with schizophrenia. Neuroscience Research. PMID 36162734 DOI: 10.1016/j.neures.2022.09.011  0.739
2022 Kim SH, An K, Namkung H, Saito A, Rannals MD, Moore JR, Mihaljevic M, Saha S, Oh S, Kondo MA, Ishizuka K, Yang K, Maher BJ, Niwa M, Sawa A. Anterior Insula-Associated Social Novelty Recognition: Pivotal Roles of a Local Retinoic Acid Cascade and Oxytocin Signaling. The American Journal of Psychiatry. appiajp21010053. PMID 36128683 DOI: 10.1176/appi.ajp.21010053  0.77
2022 Etyemez S, Narita Z, Mihaljevic M, Coughlin JM, Nestadt G, Nucifora FCJ, Sedlak TW, Cascella NG, Batt FD, Hua J, Faria A, Ishizuka K, Kamath V, Yang K, Sawa A. Brain regions associated with olfactory dysfunction in first episode psychosis patients. The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. 1-9. PMID 35678361 DOI: 10.1080/15622975.2022.2082526  0.695
2022 Jaaro-Peled H, Landek-Salgado MA, Cascella NG, Nucifora FC, Coughlin JM, Nestadt G, Sedlak TW, Lavoie J, De Silva S, Lee S, Tajinda K, Hiyama H, Ishizuka K, Yang K, Sawa A. Sex-specific involvement of the Notch-JAG pathway in social recognition. Translational Psychiatry. 12: 99. PMID 35273151 DOI: 10.1038/s41398-022-01867-4  0.799
2022 Jaaro-Peled H, Kumar S, Hughes D, Sumitomo A, Kim SH, Zoubovsky S, Hirota-Tsuyada Y, Zala D, Bruyere J, Katz BM, Huang B, Flores R, Narayan S, Hou Z, Economides AN, ... ... Ishizuka K, et al. Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit. Molecular Psychiatry. PMID 35165396 DOI: 10.1038/s41380-021-01389-3  0.782
2021 Etyemez S, Narita Z, Mihaljevic M, Ishizuka K, Kamath V, Yang K, Sawa A. Olfactory dysfunction and face processing of social cognition in first-episode psychosis. Neuroscience Research. PMID 34655664 DOI: 10.1016/j.neures.2021.10.003  0.446
2021 Narita Z, Yang K, Kuga H, Piancharoen P, Etyemez S, Faria A, Mihaljevic M, Longo L, Namkung H, Coughlin JM, Nestadt G, Nucifora FC, Sedlak TW, Schaub R, Crawford J, ... ... Ishizuka K, et al. Face processing of social cognition in patients with first episode psychosis: Its deficits and association with the right subcallosal anterior cingulate cortex. Schizophrenia Research. 238: 99-107. PMID 34649085 DOI: 10.1016/j.schres.2021.09.027  0.77
2021 Kulason S, Ratnanather JT, Miller MI, Kamath V, Hua J, Yang K, Ma M, Ishizuka K, Sawa A. A comparative neuroimaging perspective of olfaction and higher-order olfactory processing: on health and disease. Seminars in Cell & Developmental Biology. PMID 34462249 DOI: 10.1016/j.semcdb.2021.08.009  0.489
2021 Yang K, Hua J, Etyemez S, Paez A, Prasad N, Ishizuka K, Sawa A, Kamath V. Volumetric alteration of olfactory bulb and immune-related molecular changes in olfactory epithelium in first episode psychosis patients. Schizophrenia Research. 235: 9-11. PMID 34280869 DOI: 10.1016/j.schres.2021.07.016  0.406
2021 Hasegawa Y, Namkung H, Smith A, Sakamoto S, Zhu X, Ishizuka K, Lane AP, Sawa A, Kamiya A. Causal impact of local inflammation in the nasal cavity on higher brain function and cognition. Neuroscience Research. PMID 33932551 DOI: 10.1016/j.neures.2021.04.009  0.77
2020 Takayanagi Y, Ishizuka K, Laursen TM, Yukitake H, Yang K, Cascella NG, Ueda S, Sumitomo A, Narita Z, Horiuchi Y, Niwa M, Taguchi A, White MF, Eaton WW, Mortensen PB, et al. From population to neuron: exploring common mediators for metabolic problems and mental illnesses. Molecular Psychiatry. PMID 33173197 DOI: 10.1038/s41380-020-00939-5  0.706
2019 John JP, Thirunavukkarasu P, Ishizuka K, Parekh P, Sawa A. An in-silico approach for discovery of microRNA-TF regulation of DISC1 interactome mediating neuronal migration. Npj Systems Biology and Applications. 5: 17. PMID 32372023 DOI: 10.1038/s41540-019-0094-3  0.47
2019 Wen F, Armstrong N, Hou W, Cruz-Cosme R, Obwolo LA, Ishizuka K, Ullah H, Luo MH, Sawa A, Tang Q. Zika virus increases mind bomb 1 levels, causing degradation of pericentriolar material 1 (PCM1) and dispersion of PCM1 granules from the centrosome. The Journal of Biological Chemistry. PMID 31666336 DOI: 10.1074/Jbc.Ra119.010973  0.455
2019 Yang K, Kondo MA, Jaaro-Peled H, Cash-Padgett T, Kano SI, Ishizuka K, Pevsner J, Tomoda T, Sawa A, Niwa M. The transcriptome landscape associated with Disrupted-in-Schizophrenia-1 locus impairment in early development and adulthood. Schizophrenia Research. PMID 31204062 DOI: 10.1016/J.Schres.2019.05.032  0.81
2019 John JP, Thirunavukkarasu P, Ishizuka K, Parekh P, Sawa A. An in-silico approach for discovery of microRNA-TF regulation of DISC1 interactome mediating neuronal migration. Npj Systems Biology and Applications. 5: 17. PMID 31098296 DOI: 10.1038/s41540-019-0094-3  0.47
2019 Tharakan R, Kreimer S, Ubaida-Mohien C, Lavoie J, Olexiouk V, Menschaert G, Ingolia NT, Cole RN, Ishizuka K, Sawa A, Nucifora LG. A methodology for discovering novel brain-relevant peptides: Combination of ribosome profiling and peptidomics. Neuroscience Research. PMID 30862443 DOI: 10.1016/J.Neures.2019.02.006  0.673
2018 Kano SI, Hodgkinson CA, Jones-Brando L, Eastwood S, Ishizuka K, Niwa M, Choi EY, Chang DJ, Chen Y, Velivela SD, Leister F, Wood J, Chowdari K, Ducci F, Caycedo DA, et al. Host-parasite interaction associated with major mental illness. Molecular Psychiatry. PMID 30127472 DOI: 10.1038/S41380-018-0217-Z  0.8
2018 Sumitomo A, Yukitake H, Hirai K, Horike K, Ueta K, Chung Y, Warabi E, Yanagawa T, Kitaoka S, Furuyashiki T, Narumiya S, Hirano T, Niwa M, Sibille E, Hikida T, ... ... Ishizuka K, et al. Ulk2 controls cortical excitatory-inhibitory balance via autophagic regulation of p62 and GABAA receptor trafficking in pyramidal neurons. Human Molecular Genetics. PMID 29893844 DOI: 10.1093/Hmg/Ddy219  0.781
2018 Lema YY, Gamo NJ, Yang K, Ishizuka K. Trait and state biomarkers for psychiatric disorders: Importance of infrastructure to bridge the gap between basic and clinical research and industry. Psychiatry and Clinical Neurosciences. PMID 29687938 DOI: 10.1111/Pcn.12669  0.742
2018 McLean CK, Narayan S, Lin SY, Rai N, Chung Y, Hipolito MS, Cascella NG, Nurnberger JI, Ishizuka K, Sawa AS, Nwulia EA. Lithium-associated transcriptional regulation of CRMP1 in patient-derived olfactory neurons and symptom changes in bipolar disorder. Translational Psychiatry. 8: 81. PMID 29666369 DOI: 10.1038/S41398-018-0126-6  0.545
2018 Srivastava R, Faust T, Ramos A, Ishizuka K, Sawa A. Dynamic Changes of the Mitochondria in Psychiatric Illnesses: New Mechanistic Insights From Human Neuronal Models. Biological Psychiatry. PMID 29486891 DOI: 10.1016/J.Biopsych.2018.01.007  0.806
2018 Kulason S, Schretlen D, Sawa A, Ratnanather T, Ishizuka K. S228. Measuring the Relationship Between Specific Phosphorylation of DISC1 and Cortical Thickness in Psychotic Disorders Biological Psychiatry. 83: S436-S437. DOI: 10.1016/J.Biopsych.2018.02.1120  0.478
2017 Park SJ, Lee SB, Suh Y, Kim SJ, Lee N, Hong JH, Park C, Woo Y, Ishizuka K, Kim JH, Berggren PO, Sawa A, Park SK. DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM. Cell Reports. 21: 2748-2759. PMID 29212023 DOI: 10.1016/J.Celrep.2017.11.043  0.47
2017 Sagata N, Kato TA, Kano SI, Ohgidani M, Shimokawa N, Sato-Kasai M, Hayakawa K, Kuwano N, Wilson AM, Ishizuka K, Kato S, Nakahara T, Nakahara-Kido M, Setoyama D, Sakai Y, et al. Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: a pilot study. Scientific Reports. 7: 13905. PMID 29066822 DOI: 10.1038/S41598-017-14440-7  0.741
2017 Kamath V, Lasutschinkow P, Ishizuka K, Sawa A. Olfactory Functioning in First-Episode Psychosis. Schizophrenia Bulletin. PMID 28981913 DOI: 10.1093/Schbul/Sbx107  0.56
2017 Shao L, Lu B, Wen Z, Teng S, Wang L, Zhao Y, Wang L, Ishizuka K, Xu X, Sawa A, Song H, Ming G, Zhong Y. Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways. Human Molecular Genetics. PMID 28472294 DOI: 10.1093/Hmg/Ddx147  0.612
2017 Lavoie J, Sawa A, Ishizuka K. Application of olfactory tissue and its neural progenitors to schizophrenia and psychiatric research. Current Opinion in Psychiatry. PMID 28333692 DOI: 10.1097/Yco.0000000000000327  0.737
2017 Tanaka M, Ishizuka K, Nekooki-Machida Y, Endo R, Takashima N, Sasaki H, Komi Y, Gathercole A, Huston E, Ishii K, Hui KK, Kurosawa M, Kim SH, Nukina N, Takimoto E, et al. Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease. The Journal of Clinical Investigation. PMID 28263187 DOI: 10.1172/Jci85594  0.526
2017 Lavoie J, Gassó Astorga P, Segal-Gavish H, Wu YC, Chung Y, Cascella NG, Sawa A, Ishizuka K. The Olfactory Neural Epithelium As a Tool in Neuroscience. Trends in Molecular Medicine. PMID 28108112 DOI: 10.1016/J.Molmed.2016.12.010  0.738
2017 Ishizuka K, Tanaka M, Houslay M, Sawa A. 438. Amyloidogenic DISC1: Role for Psychiatric Manifestation in Neurodegenerative Disorders Biological Psychiatry. 81: S179. DOI: 10.1016/J.Biopsych.2017.02.922  0.503
2016 Horiuchi Y, Kondo MA, Okada K, Takayanagi Y, Tanaka T, Ho T, Varvaris M, Tajinda K, Hiyama H, Ni K, Colantuoni C, Schretlen D, Cascella NG, Pevsner J, Ishizuka K, et al. Molecular signatures associated with cognitive deficits in schizophrenia: a study of biopsied olfactory neural epithelium. Translational Psychiatry. 6: e915. PMID 27727244 DOI: 10.1038/Tp.2016.154  0.578
2016 Tankou S, Ishii K, Elliott C, Yalla KC, Day JP, Furukori K, Kubo KI, Brandon NJ, Tang Q, Hayward G, Nakajima K, Houslay MD, Kamiya A, Baillie G, Ishizuka K, et al. SUMOylation of DISC1: a potential role in neural progenitor proliferation in the developing cortex. Molecular Neuropsychiatry. 2: 20-27. PMID 27525255 DOI: 10.1159/000444257  0.807
2016 Jaaro-Peled H, Altimus C, LeGates T, Cash-Padgett T, Zoubovsky S, Hikida T, Ishizuka K, Hattar S, Mongrain V, Sawa A. Abnormal wake/sleep pattern in a novel gain-of-function model of DISC1. Neuroscience Research. PMID 27354230 DOI: 10.1016/J.Neures.2016.06.006  0.761
2016 Sawa A, Ishizuka K, Katsanis N. The potential of DISC1 protein as a therapeutic target for mental illness. Expert Opinion On Therapeutic Targets. PMID 26810812 DOI: 10.1517/14728222.2016.1146694  0.465
2016 Niwa M, Cash-Padgett T, Kubo KI, Saito A, Ishii K, Sumitomo A, Taniguchi Y, Ishizuka K, Jaaro-Peled H, Tomoda T, Nakajima K, Sawa A, Kamiya A. DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1 Molecular Psychiatry. DOI: 10.1038/Mp.2016.154  0.799
2015 Seshadri S, Faust T, Ishizuka K, Delevich K, Chung Y, Kim SH, Cowles M, Niwa M, Jaaro-Peled H, Tomoda T, Lai C, Anton ES, Li B, Sawa A. Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortex. Nature Communications. 6: 10118. PMID 26656849 DOI: 10.1038/Ncomms10118  0.8
2015 Passeri E, Wilson AM, Primerano A, Kondo MA, Sengupta S, Srivastava R, Koga M, Obie C, Zandi PP, Goes FS, Valle D, Rapoport JL, Sawa A, Kano SI, Ishizuka K. Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities. Neuroscience Research. PMID 26260244 DOI: 10.1016/J.Neures.2015.07.011  0.784
2015 Barodia SK, Park SK, Ishizuka K, Sawa A, Kamiya A. Half-life of DISC1 protein and its pathological significance under hypoxia stress. Neuroscience Research. 97: 1-6. PMID 25738396 DOI: 10.1016/J.Neures.2015.02.008  0.648
2015 Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, et al. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Current Molecular Medicine. 15: 138-45. PMID 25732146 DOI: 10.2174/1566524015666150303110300  0.788
2015 Tristan CA, Ramos A, Shahani N, Emiliani FE, Nakajima H, Noeh CC, Kato Y, Takeuchi T, Noguchi T, Kadowaki H, Sedlak TW, Ishizuka K, Ichijo H, Sawa A. Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade. The Journal of Biological Chemistry. 290: 56-64. PMID 25391652 DOI: 10.1074/Jbc.M114.596205  0.75
2015 Shahani N, Seshadri S, Jaaro-Peled H, Ishizuka K, Hirota-Tsuyada Y, Wang Q, Koga M, Sedlak TW, Korth C, Brandon NJ, Kamiya A, Subramaniam S, Tomoda T, Sawa A. DISC1 regulates trafficking and processing of APP and Aβ generation. Molecular Psychiatry. 20: 874-9. PMID 25224257 DOI: 10.1038/Mp.2014.100  0.792
2014 Narayan S, McLean C, Sawa A, Lin SY, Rai N, Hipolito MS, Cascella N, Nurnberger JJ, Ishizuka K, Nwulia EA. Olfactory neurons obtained through nasal biopsy combined with laser-capture microdissection: a potential approach to study treatment response in mental disorders. Journal of Visualized Experiments : Jove. PMID 25549156 DOI: 10.3791/51853  0.549
2014 Sawa A, Horiuchi Y, Cascella N, Schretlen D, Ishizuka K. ELUCIDATING THE MOLECULAR PATHOPHYSIOLOGY OF MENTAL ILLNESS WITH OLFACTORY NEURONAL CELLS AND INDUCED PLURIPOTENT STEM CELLS Schizophrenia Research. 153: S45. DOI: 10.1016/S0920-9964(14)70146-X  0.522
2013 Horiuchi Y, Kano S, Ishizuka K, Cascella NG, Ishii S, Talbot CC, Jaffe AE, Okano H, Pevsner J, Colantuoni C, Sawa A. Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders. Neuroscience Research. 77: 247-50. PMID 24120685 DOI: 10.1016/J.Neures.2013.09.010  0.748
2013 Soda T, Frank C, Ishizuka K, Baccarella A, Park YU, Flood Z, Park SK, Sawa A, Tsai LH. DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. Molecular Psychiatry. 18: 898-908. PMID 23587879 DOI: 10.1038/mp.2013.38  0.518
2013 Coughlin JM, Ishizuka K, Kano SI, Edwards JA, Seifuddin FT, Shimano MA, Daley EL, Zandi PP, Leweke FM, Cascella NG, Pomper MG, Yolken RH, Sawa A. Marked reduction of soluble superoxide dismutase-1 (SOD1) in cerebrospinal fluid of patients with recent-onset schizophrenia. Molecular Psychiatry. 18: 10-1. PMID 22349781 DOI: 10.1038/Mp.2012.6  0.817
2012 Bader V, Tomppo L, Trossbach SV, Bradshaw NJ, Prikulis I, Leliveld SR, Lin CY, Ishizuka K, Sawa A, Ramos A, Rosa I, García Á, Requena JR, Hipolito M, Rai N, et al. Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits. Human Molecular Genetics. 21: 4406-18. PMID 22798627 DOI: 10.1093/Hmg/Dds273  0.823
2011 Ishizuka K, Kamiya A, Oh EC, Kanki H, Seshadri S, Robinson JF, Murdoch H, Dunlop AJ, Kubo K, Furukori K, Huang B, Zeledon M, Hayashi-Takagi A, Okano H, Nakajima K, et al. DISC1-dependent switch from progenitor proliferation to migration in the developing cortex. Nature. 473: 92-6. PMID 21471969 DOI: 10.1038/Nature09859  0.784
2011 Wang Q, Charych EI, Pulito VL, Lee JB, Graziane NM, Crozier RA, Revilla-Sanchez R, Kelly MP, Dunlop AJ, Murdoch H, Taylor N, Xie Y, Pausch M, Hayashi-Takagi A, Ishizuka K, et al. The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. Molecular Psychiatry. 16: 1006-23. PMID 20838393 DOI: 10.1038/Mp.2010.87  0.785
2010 Abazyan B, Nomura J, Kannan G, Ishizuka K, Tamashiro KL, Nucifora F, Pogorelov V, Ladenheim B, Yang C, Krasnova IN, Cadet JL, Pardo C, Mori S, Kamiya A, Vogel MW, et al. Prenatal interaction of mutant DISC1 and immune activation produces adult psychopathology. Biological Psychiatry. 68: 1172-81. PMID 21130225 DOI: 10.1016/J.Biopsych.2010.09.022  0.681
2010 Seshadri S, Kamiya A, Yokota Y, Prikulis I, Kano S, Hayashi-Takagi A, Stanco A, Eom TY, Rao S, Ishizuka K, Wong P, Korth C, Anton ES, Sawa A. Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. Proceedings of the National Academy of Sciences of the United States of America. 107: 5622-7. PMID 20212127 DOI: 10.1073/Pnas.0909284107  0.814
2010 Tajinda K, Ishizuka K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella NG. Neuronal biomarkers from patients with mental illnesses: a novel method through nasal biopsy combined with laser-captured microdissection. Molecular Psychiatry. 15: 231-2. PMID 20168323 DOI: 10.1038/Mp.2009.73  0.461
2010 Hayashi-Takagi A, Takaki M, Graziane N, Seshadri S, Murdoch H, Dunlop AJ, Makino Y, Seshadri AJ, Ishizuka K, Srivastava DP, Xie Z, Baraban JM, Houslay MD, Tomoda T, Brandon NJ, et al. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nature Neuroscience. 13: 327-32. PMID 20139976 DOI: 10.1038/Nn.2487  0.814
2010 Ishizuka K, Tajinda K, Colantuoni C, Morita M, Winicki J, Le C, Lin S, Schretlen D, Sawa A, Cascella NG. Negative symptoms of schizophrenia correlate with impairment on the University of Pennsylvania smell identification test. Neuroscience Research. 66: 106-10. PMID 19819272 DOI: 10.1016/J.Neures.2009.10.001  0.503
2010 Ishizuka K, Kano S, Colantuoni C, Schretlen D, Cascella NG, Sawa A. A translational approach for schizophrenia: Systematic cell/tissue engineering combined with detailed phenotypic characterization and molecular brain imaging Neuroscience Research. 68: e18. DOI: 10.1016/J.Neures.2010.07.315  0.756
2010 Horiuchi Y, Ishii S, Kano S, Ishizuka K, Okada Y, Colantuoni C, Valle D, Cascella NG, Akamatsu W, Sawa A, Okano H. Generation of induced pluripotent stem cells from patients with schizophrenia Neuroscience Research. 68: e314. DOI: 10.1016/J.Neures.2010.07.1395  0.747
2008 Sawamura N, Ando T, Maruyama Y, Fujimuro M, Mochizuki H, Honjo K, Shimoda M, Toda H, Sawamura-Yamamoto T, Makuch LA, Hayashi A, Ishizuka K, Cascella NG, Kamiya A, Ishida N, et al. Nuclear DISC1 regulates CRE-mediated gene transcription and sleep homeostasis in the fruit fly. Molecular Psychiatry. 13: 1138-48, 1069. PMID 18762802 DOI: 10.1038/Mp.2008.101  0.668
2008 Kamiya A, Tan PL, Kubo K, Engelhard C, Ishizuka K, Kubo A, Tsukita S, Pulver AE, Nakajima K, Cascella NG, Katsanis N, Sawa A. Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. Archives of General Psychiatry. 65: 996-1006. PMID 18762586 DOI: 10.1001/Archpsyc.65.9.996  0.687
2008 Burdick KE, Kamiya A, Hodgkinson CA, Lencz T, DeRosse P, Ishizuka K, Elashvili S, Arai H, Goldman D, Sawa A, Malhotra AK. Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding. Human Molecular Genetics. 17: 2462-73. PMID 18469341 DOI: 10.1093/Hmg/Ddn146  0.636
2007 Ishizuka K, Chen J, Taya S, Li W, Millar JK, Xu Y, Clapcote SJ, Hookway C, Morita M, Kamiya A, Tomoda T, Lipska BK, Roder JC, Pletnikov M, Porteous D, et al. Evidence that many of the DISC1 isoforms in C57BL/6J mice are also expressed in 129S6/SvEv mice. Molecular Psychiatry. 12: 897-9. PMID 17895924 DOI: 10.1038/Sj.Mp.4002024  0.754
2007 Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, Kong S, Wu D, Xue R, Andradé M, Tankou S, Mori S, Gallagher M, Ishizuka K, Pletnikov M, Kida S, et al. Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans. Proceedings of the National Academy of Sciences of the United States of America. 104: 14501-6. PMID 17675407 DOI: 10.1073/Pnas.0704774104  0.796
2006 Maeda K, Nwulia E, Chang J, Balkissoon R, Ishizuka K, Chen H, Zandi P, McInnis MG, Sawa A. Differential expression of disrupted-in-schizophrenia (DISC1) in bipolar disorder. Biological Psychiatry. 60: 929-35. PMID 16814263 DOI: 10.1016/J.Biopsych.2006.03.032  0.564
2006 Ishizuka K, Paek M, Kamiya A, Sawa A. A review of Disrupted-In-Schizophrenia-1 (DISC1): neurodevelopment, cognition, and mental conditions. Biological Psychiatry. 59: 1189-97. PMID 16797264 DOI: 10.1016/J.Biopsych.2006.03.065  0.716
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