Gail E. Besner, M.D. - Publications

Affiliations: 
Nationwide Children's Hospital, Columbus, OH 

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Nordin AB, Diefenbach K, Sales SP, Christensen J, Besner GE, Kenney BD. Gangrenous appendicitis: No longer complicated. Journal of Pediatric Surgery. PMID 30551843 DOI: 10.1016/j.jpedsurg.2018.10.064  0.48
2018 Cromeens BP, Wang Y, Liu Y, Johnson J, Besner GE. Critical intestinal cells originate from the host in enteroid-derived tissue-engineered intestine. The Journal of Surgical Research. 223: 155-164. PMID 29433868 DOI: 10.1016/j.jss.2017.11.015  0.4
2018 Liu Y, Cromeens BP, Wang Y, Fisher K, Johnson J, Chakroff J, Besner GE. Comparison of Different in vivo Incubation Sites to Produce Tissue Engineered Small Intestine. Tissue Engineering. Part A. PMID 29383981 DOI: 10.1089/ten.TEA.2017.0313  0.4
2017 Nordin AB, Sales SP, Besner GE, Levitt MA, Wood RJ, Kenney BD. Effective methods to decrease surgical site infections in pediatric gastrointestinal surgery. Journal of Pediatric Surgery. PMID 29108847 DOI: 10.1016/j.jpedsurg.2017.10.018  0.48
2017 Cromeens BP, Ray WC, Hoehne B, Abayneh F, Adler B, Besner GE. Facilitating surgeon understanding of complex anatomy using a three-dimensional printed model. The Journal of Surgical Research. 216: 18-25. PMID 28807205 DOI: 10.1016/j.jss.2017.04.003  0.4
2017 Cromeens BP, Lisciandro RE, Brilli RJ, Askegard-Giesmann JR, Kenney BD, Besner GE. Identifying Adverse Events in Pediatric Surgery: Comparing Morbidity and Mortality Conference to the NSQIP-Pediatric. Journal of the American College of Surgeons. PMID 28235646 DOI: 10.1016/j.jamcollsurg.2017.02.008  0.48
2016 Shen J, Giles SA, Kurtovic K, Fabia R, Besner GE, Wheeler KK, Xiang H, Groner JI. Evaluation of nurse accuracy in rating procedural pain among pediatric burn patients using the Face, Legs, Activity, Cry, Consolability (FLACC) Scale. Burns : Journal of the International Society For Burn Injuries. PMID 27576937 DOI: 10.1016/j.burns.2016.07.009  0.48
2016 Johnson SA, Shi J, Groner JI, Thakkar RK, Fabia R, Besner GE, Xiang H, Wheeler KK. Inter-facility transfer of pediatric burn patients from U.S. Emergency Departments. Burns : Journal of the International Society For Burn Injuries. PMID 27554628 DOI: 10.1016/j.burns.2016.06.024  0.48
2016 Cromeens BP, Liu Y, Stathopoulos J, Wang Y, Johnson J, Besner GE. Production of tissue-engineered intestine from expanded enteroids. The Journal of Surgical Research. 204: 164-75. PMID 27451883 DOI: 10.1016/j.jss.2016.02.030  0.4
2016 Liu Y, Nelson T, Cromeens B, Rager T, Lannutti J, Johnson J, Besner GE. HB-EGF embedded in PGA/PLLA scaffolds via subcritical CO2 augments the production of tissue engineered intestine. Biomaterials. 103: 150-159. PMID 27380441 DOI: 10.1016/j.biomaterials.2016.06.039  0.84
2016 Rager TM, Olson JK, Zhou Y, Wang Y, Besner GE. Exosomes secreted from bone marrow-derived mesenchymal stem cells protect the intestines from experimental necrotizing enterocolitis. Journal of Pediatric Surgery. PMID 27015901 DOI: 10.1016/j.jpedsurg.2016.02.061  0.84
2016 Zhang HY, Besner GE, Feng JX. Antibody blockade of mucosal addressin cell adhesion molecule-1 attenuates proinflammatory activity of mesenteric lymph after hemorrhagic shock and resuscitation. Surgery. PMID 26804820 DOI: 10.1016/j.surg.2015.12.013  0.84
2015 Boomer LA, Cooper JN, Anandalwar S, Fallon SC, Ostlie D, Leys CM, Rangel S, Mattei P, Sharp SW, St Peter SD, Rodriguez JR, Kenney B, Besner GE, Deans KJ, Minneci PC. Delaying Appendectomy Does Not Lead to Higher Rates of Surgical Site Infections: A Multi-institutional Analysis of Children With Appendicitis. Annals of Surgery. PMID 26692077 DOI: 10.1097/SLA.0000000000001396  0.84
2015 Zhou Y, Besner G. Transplantation of amniotic fluid-derived neural stem cells as a potential novel therapy for Hirschsprung's disease. Journal of Pediatric Surgery. PMID 26597391 DOI: 10.1016/j.jpedsurg.2015.10.016  0.84
2015 Cromeens B, Brilli R, Kurtovic K, Kenney B, Nwomeh B, Besner GE. Implementation of a pediatric surgical quality improvement (QI)-driven M&M conference. Journal of Pediatric Surgery. PMID 26581322 DOI: 10.1016/j.jpedsurg.2015.10.032  0.84
2015 Emamaullee JE, Besner GE. Profiles in surgical research: Dorry L. Segev, MD, PhD, FACS. Bulletin of the American College of Surgeons. 100: 27-33. PMID 26248397  0.84
2015 Wei J, Besner GE. M1 to M2 macrophage polarization in heparin-binding epidermal growth factor-like growth factor therapy for necrotizing enterocolitis. The Journal of Surgical Research. 197: 126-38. PMID 25913486 DOI: 10.1016/j.jss.2015.03.023  0.84
2015 Wei J, Zhou Y, Besner GE. Heparin-binding EGF-like growth factor and enteric neural stem cell transplantation in the prevention of experimental necrotizing enterocolitis in mice. Pediatric Research. 78: 29-37. PMID 25806717 DOI: 10.1038/pr.2015.63  0.84
2015 Boomer LA, Watkins DJ, O'Donovan J, Kenney BD, Yates AR, Besner GE. An unusual case of foreign body pulmonary embolus: case report and review of penetrating trauma at a pediatric trauma center. Pediatric Surgery International. 31: 241-7. PMID 25633156 DOI: 10.1007/s00383-015-3659-2  0.84
2015 Raval MV, Rust L, Thakkar RK, Kurtovic KJ, Nwomeh BC, Besner GE, Kenney BD. Development and implementation of an electronic health record generated surgical handoff and rounding tool. Journal of Medical Systems. 39: 8. PMID 25631842 DOI: 10.1007/s10916-015-0202-x  0.84
2015 Harrison MR, Emamaullee JE, Besner GE. Profiles in surgical research: Michael R. Harrison, MD, FACS. Bulletin of the American College of Surgeons. 100: 35-40. PMID 25626264  0.84
2015 Liu Y, Rager T, Johnson J, Enmark J, Besner GE. Enriched Intestinal Stem Cell Seeding Improves the Architecture of Tissue-Engineered Intestine. Tissue Engineering. Part C, Methods. PMID 25603285 DOI: 10.1089/ten.TEC.2014.0389  0.84
2015 Besner GE. A pain in the NEC: research challenges and opportunities. Journal of Pediatric Surgery. 50: 23-9. PMID 25598088 DOI: 10.1016/j.jpedsurg.2014.10.024  0.84
2014 Sood BG, Keszler M, Garg M, Klein JM, Ohls R, Ambalavanan N, Cotten CM, Malian M, Sanchez PJ, Lakshminrusimha S, Nelin LD, Van Meurs KP, Bara R, Saha S, Das A, et al. Inhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials. Trials. 15: 486. PMID 25496504 DOI: 10.1186/1745-6215-15-486  0.84
2014 Yang J, Su Y, Besner GE. Stem cell therapy for necrotizing enterocolitis: innovative techniques and procedures for pediatric translational research. Methods in Molecular Biology (Clifton, N.J.). 1213: 121-37. PMID 25173379 DOI: 10.1007/978-1-4939-1453-1_11  0.84
2014 Muszynski JA, Nofziger R, Greathouse K, Nateri J, Hanson-Huber L, Steele L, Nicol K, Groner JI, Besner GE, Raffel C, Geyer S, El-Assal O, Hall MW. Innate immune function predicts the development of nosocomial infection in critically injured children. Shock (Augusta, Ga.). 42: 313-21. PMID 24978895 DOI: 10.1097/SHK.0000000000000217  0.84
2014 Boomer LA, Cooper JN, Deans KJ, Minneci PC, Leonhart K, Diefenbach KA, Kenney BD, Besner GE. Does delay in appendectomy affect surgical site infection in children with appendicitis? Journal of Pediatric Surgery. 49: 1026-9; discussion 1. PMID 24888856 DOI: 10.1016/j.jpedsurg.2014.01.044  0.84
2014 Watkins DJ, Zhou Y, Matthews MA, Chen L, Besner GE. HB-EGF augments the ability of mesenchymal stem cells to attenuate intestinal injury. Journal of Pediatric Surgery. 49: 938-44; discussion 9. PMID 24888839 DOI: 10.1016/j.jpedsurg.2014.01.030  0.84
2014 Chen CL, Yang J, James IO, Zhang HY, Besner GE. Heparin-binding epidermal growth factor-like growth factor restores Wnt/β-catenin signaling in intestinal stem cells exposed to ischemia/reperfusion injury. Surgery. 155: 1069-80. PMID 24856127 DOI: 10.1016/j.surg.2014.01.013  0.84
2014 Su Y, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) promotes cell migration and adhesion via focal adhesion kinase. The Journal of Surgical Research. 189: 222-31. PMID 24703506 DOI: 10.1016/j.jss.2014.02.055  0.84
2014 Wei J, Li N, Xia X, Chen X, Peng F, Besner GE, Feng J. Effects of lipopolysaccharide-induced inflammation on the interstitial cells of Cajal. Cell and Tissue Research. 356: 29-37. PMID 24435644 DOI: 10.1007/s00441-013-1775-7  0.84
2014 Yang J, Su Y, Zhou Y, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) therapy for intestinal injury: Application and future prospects. Pathophysiology : the Official Journal of the International Society For Pathophysiology / Isp. 21: 95-104. PMID 24345808 DOI: 10.1016/j.pathophys.2013.11.008  0.84
2014 Boomer L, Liu Y, Mahler N, Johnson J, Zak K, Nelson T, Lannutti J, Besner GE. Scaffolding for challenging environments: materials selection for tissue engineered intestine. Journal of Biomedical Materials Research. Part A. 102: 3795-802. PMID 24288210 DOI: 10.1002/jbm.a.35047  0.84
2013 Zhou Y, Yang J, Watkins DJ, Boomer LA, Matthews MA, Su Y, Besner GE. Enteric nervous system abnormalities are present in human necrotizing enterocolitis: potential neurotransplantation therapy. Stem Cell Research & Therapy. 4: 157. PMID 24423414 DOI: 10.1186/scrt387  0.84
2013 Watkins DJ, Yang J, Matthews MA, Besner GE. Synergistic effects of HB-EGF and mesenchymal stem cells in a murine model of intestinal ischemia/reperfusion injury. Journal of Pediatric Surgery. 48: 1323-9. PMID 23845626 DOI: 10.1016/j.jpedsurg.2013.03.032  0.84
2013 Matthews MA, Watkins D, Darbyshire A, Carson WE, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) protects the intestines from radiation therapy-induced intestinal injury. Journal of Pediatric Surgery. 48: 1316-22. PMID 23845625 DOI: 10.1016/j.jpedsurg.2013.03.030  0.84
2013 Lutmer J, Watkins D, Chen CL, Velten M, Besner G. Heparin-binding epidermal growth factor-like growth factor attenuates acute lung injury and multiorgan dysfunction after scald burn. The Journal of Surgical Research. 185: 329-37. PMID 23777985 DOI: 10.1016/j.jss.2013.05.064  0.84
2013 Matthews MA, Adler BH, Arnold MA, Kumar S, Carvalho R, Besner GE. Diffuse intestinal ganglioneuromatosis in a child. Journal of Pediatric Surgery. 48: 1129-33. PMID 23701793 DOI: 10.1016/j.jpedsurg.2013.03.066  0.84
2013 Watkins DJ, Besner GE. The role of the intestinal microcirculation in necrotizing enterocolitis. Seminars in Pediatric Surgery. 22: 83-7. PMID 23611611 DOI: 10.1053/j.sempedsurg.2013.01.004  0.84
2013 Su Y, Yang J, Besner GE. HB-EGF promotes intestinal restitution by affecting integrin-extracellular matrix interactions and intercellular adhesions. Growth Factors (Chur, Switzerland). 31: 39-55. PMID 23305395 DOI: 10.3109/08977194.2012.755966  0.84
2013 Odar C, Kirschman KJ, Pelley TJ, Butz C, Besner GE, Fabia RB. Prevalence and correlates of posttraumatic stress in parents of young children postburn. Journal of Burn Care & Research : Official Publication of the American Burn Association. 34: 299-306. PMID 23128125 DOI: 10.1097/BCR.0b013e31825ae15d  0.84
2013 Yang J, Radulescu A, Chen CL, Zhang HY, James IO, Besner GE. Heparin-binding epidermal growth factor-like growth factor improves intestinal barrier function and reduces mortality in a murine model of peritonitis. Surgery. 153: 52-62. PMID 22703966 DOI: 10.1016/j.surg.2012.04.002  0.84
2012 Yang J, Watkins D, Chen CL, Zhang HY, Zhou Y, Velten M, Besner GE. A technique for systemic mesenchymal stem cell transplantation in newborn rat pups. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 25: 405-14. PMID 23215798 DOI: 10.3109/08941939.2012.661519  0.84
2012 Zhou Y, James I, Besner GE. Heparin-binding epidermal growth factor-like growth factor promotes murine enteric nervous system development and enteric neural crest cell migration. Journal of Pediatric Surgery. 47: 1865-73. PMID 23084199 DOI: 10.1016/j.jpedsurg.2012.05.008  0.84
2012 Yang J, Watkins D, Chen CL, Bhushan B, Zhou Y, Besner GE. Heparin-binding epidermal growth factor-like growth factor and mesenchymal stem cells act synergistically to prevent experimental necrotizing enterocolitis. Journal of the American College of Surgeons. 215: 534-45. PMID 22819639 DOI: 10.1016/j.jamcollsurg.2012.05.037  0.84
2012 Watkins DJ, Zhou Y, Chen CL, Darbyshire A, Besner GE. Heparin-binding epidermal growth factor-like growth factor protects mesenchymal stem cells. The Journal of Surgical Research. 177: 359-64. PMID 22658491 DOI: 10.1016/j.jss.2012.05.016  0.84
2012 Huang G, Besner GE, Brigstock DR. Heparin-binding epidermal growth factor-like growth factor suppresses experimental liver fibrosis in mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 703-12. PMID 22330337 DOI: 10.1038/labinvest.2012.3  0.84
2012 Chen CL, Yu X, James IO, Zhang HY, Yang J, Radulescu A, Zhou Y, Besner GE. Heparin-binding EGF-like growth factor protects intestinal stem cells from injury in a rat model of necrotizing enterocolitis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 331-44. PMID 22157721 DOI: 10.1038/labinvest.2011.167  0.84
2012 Zhang HY, James I, Chen CL, Besner GE. Heparin-binding epidermal growth factor-like growth factor (HB-EGF) preserves gut barrier function by blocking neutrophil-endothelial cell adhesion after hemorrhagic shock and resuscitation in mice. Surgery. 151: 594-605. PMID 22153812 DOI: 10.1016/j.surg.2011.10.001  0.84
2012 Lambert DK, Christensen RD, Baer VL, Henry E, Gordon PV, Besner GE, Wilkes J, Wiedmeier SE, Gerday E. Fulminant necrotizing enterocolitis in a multihospital healthcare system. Journal of Perinatology : Official Journal of the California Perinatal Association. 32: 194-8. PMID 21566569 DOI: 10.1038/jp.2011.61  0.84
2012 Yu X, Radulescu A, Chen CL, James IO, Besner GE. Heparin-binding EGF-like growth factor protects pericytes from injury. The Journal of Surgical Research. 172: 165-76. PMID 20863525 DOI: 10.1016/j.jss.2010.07.058  0.84
2011 Rocourt DV, Hall M, Kenney BD, Fabia R, Groner JI, Besner GE. Respiratory failure after pediatric scald injury. Journal of Pediatric Surgery. 46: 1753-8. PMID 21929985 DOI: 10.1016/j.jpedsurg.2011.04.018  0.84
2011 Giannone PJ, Alcamo AA, Schanbacher BL, Nankervis CA, Besner GE, Bauer JA. Poly(ADP-ribose) polymerase-1: a novel therapeutic target in necrotizing enterocolitis. Pediatric Research. 70: 67-71. PMID 21399558 DOI: 10.1203/PDR.0b013e31821928ff  0.84
2011 Zhang HY, Radulescu A, Chen CL, Olson JK, Darbyshire AK, Besner GE. Mice overexpressing the gene for heparin-binding epidermal growth factor-like growth factor (HB-EGF) have increased resistance to hemorrhagic shock and resuscitation. Surgery. 149: 276-83. PMID 20965535 DOI: 10.1016/j.surg.2010.08.003  0.84
2011 Radulescu A, Zhang HY, Chen CL, Chen Y, Zhou Y, Yu X, Otabor I, Olson JK, Besner GE. Heparin-binding EGF-like growth factor promotes intestinal anastomotic healing. The Journal of Surgical Research. 171: 540-50. PMID 20850767 DOI: 10.1016/j.jss.2010.06.036  0.84
2011 Zhang HY, Radulescu A, Chen Y, Besner GE. HB-EGF improves intestinal microcirculation after hemorrhagic shock. The Journal of Surgical Research. 171: 218-25. PMID 20421109 DOI: 10.1016/j.jss.2010.01.024  0.84
2011 Besner GE. Burns Fundamentals of Pediatric Surgery. 123-133. DOI: 10.1007/978-1-4419-6643-8_17  0.84
2010 Radulescu A, Zhang HY, Yu X, Olson JK, Darbyshire AK, Chen Y, Besner GE. Heparin-binding epidermal growth factor-like growth factor overexpression in transgenic mice increases resistance to necrotizing enterocolitis. Journal of Pediatric Surgery. 45: 1933-9. PMID 20920709 DOI: 10.1016/j.jpedsurg.2010.05.002  0.84
2010 Zhou Y, Besner GE. Heparin-binding epidermal growth factor-like growth factor is a potent neurotrophic factor for PC12 cells. Neuro-Signals. 18: 141-51. PMID 20847549 DOI: 10.1159/000319823  0.84
2010 Askegard-Giesmann JR, Besner GE, Fabia R, Caniano DA, Preston T, Kenney BD. Extracorporeal membrane oxygenation as a lifesaving modality in the treatment of pediatric patients with burns and respiratory failure. Journal of Pediatric Surgery. 45: 1330-5. PMID 20620340 DOI: 10.1016/j.jpedsurg.2010.02.106  0.84
2010 James IA, Chen CL, Huang G, Zhang HY, Velten M, Besner GE. HB-EGF protects the lungs after intestinal ischemia/reperfusion injury. The Journal of Surgical Research. 163: 86-95. PMID 20599214 DOI: 10.1016/j.jss.2010.03.062  0.84
2010 Christensen RD, Gordon PV, Besner GE. Can we cut the incidence of necrotizing enterocolitis in half--today? Fetal and Pediatric Pathology. 29: 185-98. PMID 20594142 DOI: 10.3109/15513815.2010.483874  0.84
2010 Radulescu A, Yu X, Orvets ND, Chen Y, Zhang HY, Besner GE. Deletion of the heparin-binding epidermal growth factor-like growth factor gene increases susceptibility to necrotizing enterocolitis. Journal of Pediatric Surgery. 45: 729-34. PMID 20385279 DOI: 10.1016/j.jpedsurg.2009.06.035  0.84
2010 Chen CL, Mehta VB, Zhang HY, Wu D, Otabor I, Radulescu A, El-Assal ON, Feng J, Chen Y, Besner GE. Intestinal phenotype in mice overexpressing a heparin-binding EGF-like growth factor transgene in enterocytes. Growth Factors (Chur, Switzerland). 28: 82-97. PMID 19939201 DOI: 10.3109/08977190903407365  0.84
2010 Christensen RD, Wiedmeier SE, Baer VL, Henry E, Gerday E, Lambert DK, Burnett J, Besner GE. Antecedents of Bell stage III necrotizing enterocolitis. Journal of Perinatology : Official Journal of the California Perinatal Association. 30: 54-7. PMID 19609307 DOI: 10.1038/jp.2009.93  0.84
2009 Zhang HY, Radulescu A, Besner GE. Heparin-binding epidermal growth factor-like growth factor is essential for preservation of gut barrier function after hemorrhagic shock and resuscitation in mice. Surgery. 146: 334-9. PMID 19628093 DOI: 10.1016/j.surg.2009.02.020  0.84
2009 Zhou Y, Brigstock D, Besner GE. Heparin-binding EGF-like growth factor is a potent dilator of terminal mesenteric arterioles. Microvascular Research. 78: 78-85. PMID 19389413 DOI: 10.1016/j.mvr.2009.04.006  0.84
2009 Yu X, Radulescu A, Zorko N, Besner GE. Heparin-binding EGF-like growth factor increases intestinal microvascular blood flow in necrotizing enterocolitis. Gastroenterology. 137: 221-30. PMID 19361505 DOI: 10.1053/j.gastro.2009.03.060  0.84
2009 Otabor IA, Balint JP, Besner GE. Myectomy-myotomy for long segment Hirschsprung's disease in a patient with Haddad syndrome. Journal of Pediatric Surgery. 44: 620-2. PMID 19302869 DOI: 10.1016/j.jpedsurg.2008.10.115  0.84
2009 Otabor IA, Abdessalam SF, Erdman SH, Hammond S, Besner GE. Gastric outlet obstruction due to adenocarcinoma in a patient with Ataxia-Telangiectasia syndrome: a case report and review of the literature. World Journal of Surgical Oncology. 7: 29. PMID 19284625 DOI: 10.1186/1477-7819-7-29  0.84
2009 Radulescu A, Zorko NA, Yu X, Besner GE. Preclinical neonatal rat studies of heparin-binding EGF-like growth factor in protection of the intestines from necrotizing enterocolitis. Pediatric Research. 65: 437-42. PMID 19127210 DOI: 10.1203/PDR.0b013e3181994fa0  0.84
2008 Mehta VB, Zhou Y, Radulescu A, Besner GE. HB-EGF stimulates eNOS expression and nitric oxide production and promotes eNOS dependent angiogenesis. Growth Factors (Chur, Switzerland). 26: 301-15. PMID 18925469 DOI: 10.1080/08977190802393596  0.84
2008 Arora A, Caniano DA, Hammond S, Besner GE. Inversion appendectomy acting as a lead point for intussusception. Pediatric Surgery International. 24: 1261-4. PMID 18810462 DOI: 10.1007/s00383-008-2250-5  0.84
2008 El-Assal ON, Paddock H, Marquez A, Besner GE. Heparin-binding epidermal growth factor-like growth factor gene disruption is associated with delayed intestinal restitution, impaired angiogenesis, and poor survival after intestinal ischemia in mice. Journal of Pediatric Surgery. 43: 1182-90. PMID 18558204 DOI: 10.1016/j.jpedsurg.2008.02.053  0.84
2008 Shiels WE, Kenney BD, Caniano DA, Besner GE. Definitive percutaneous treatment of lymphatic malformations of the trunk and extremities. Journal of Pediatric Surgery. 43: 136-9; discussion 14. PMID 18206471 DOI: 10.1016/j.jpedsurg.2007.09.049  0.84
2007 Mehta VB, Besner GE. HB-EGF promotes angiogenesis in endothelial cells via PI3-kinase and MAPK signaling pathways. Growth Factors (Chur, Switzerland). 25: 253-63. PMID 18092233 DOI: 10.1080/08977190701773070  0.84
2007 El-Assal ON, Radulescu A, Besner GE. Heparin-binding EGF-like growth factor preserves mesenteric microcirculatory blood flow and protects against intestinal injury in rats subjected to hemorrhagic shock and resuscitation. Surgery. 142: 234-42. PMID 17689691 DOI: 10.1016/j.surg.2007.04.003  0.84
2007 Rocourt DV, Mehta VB, Wu D, Besner GE. Heparin-binding EGF-like growth factor decreases neutrophil-endothelial cell interactions. The Journal of Surgical Research. 141: 262-6. PMID 17574583 DOI: 10.1016/j.jss.2007.01.004  0.84
2007 Paddock HN, Fabia R, Giles S, Hayes J, Lowell W, Besner GE. A silver impregnated antimicrobial dressing reduces hospital length of stay for pediatric patients with burns. Journal of Burn Care & Research : Official Publication of the American Burn Association. 28: 409-11. PMID 17438510 DOI: 10.1097/BCR.0B013E318053D2B9  0.84
2007 Lambert DK, Christensen RD, Henry E, Besner GE, Baer VL, Wiedmeier SE, Stoddard RA, Miner CA, Burnett J. Necrotizing enterocolitis in term neonates: data from a multihospital health-care system. Journal of Perinatology : Official Journal of the California Perinatal Association. 27: 437-43. PMID 17392837 DOI: 10.1038/sj.jp.7211738  0.84
2007 Rocourt DV, Mehta VB, Besner GE. Heparin-binding EGF-like growth factor decreases inflammatory cytokine expression after intestinal ischemia/reperfusion injury. The Journal of Surgical Research. 139: 269-73. PMID 17291530 DOI: 10.1016/j.jss.2006.10.047  0.84
2007 Feng J, Besner GE. Heparin-binding epidermal growth factor-like growth factor promotes enterocyte migration and proliferation in neonatal rats with necrotizing enterocolitis. Journal of Pediatric Surgery. 42: 214-20. PMID 17208569 DOI: 10.1016/j.jpedsurg.2006.09.055  0.84
2007 Paddock HN, Fabia R, Giles S, Hayes J, Lowell W, Adams D, Besner GE. A silver-impregnated antimicrobial dressing reduces hospital costs for pediatric burn patients. Journal of Pediatric Surgery. 42: 211-3. PMID 17208568 DOI: 10.1016/j.jpedsurg.2006.09.053  0.84
2007 Nowicki PT, Caniano DA, Hammond S, Giannone PJ, Besner GE, Reber KM, Nankervis CA. Endothelial nitric oxide synthase in human intestine resected for necrotizing enterocolitis. The Journal of Pediatrics. 150: 40-5. PMID 17188611 DOI: 10.1016/j.jpeds.2006.09.029  0.84
2006 Rocourt DV, Shiels WE, Hammond S, Besner GE. Contemporary management of benign hepatic adenoma using percutaneous radiofrequency ablation. Journal of Pediatric Surgery. 41: 1149-52. PMID 16769351 DOI: 10.1016/j.jpedsurg.2006.01.064  0.84
2006 Feng J, El-Assal ON, Besner GE. Heparin-binding epidermal growth factor-like growth factor reduces intestinal apoptosis in neonatal rats with necrotizing enterocolitis. Journal of Pediatric Surgery. 41: 742-7; discussion 74. PMID 16567187 DOI: 10.1016/j.jpedsurg.2005.12.020  0.84
2006 Nowicki PT, Reber KM, Giannone PJ, Nankervis CA, Hammond S, Besner GE, Caniano DA. Intestinal O2 consumption in necrotizing enterocolitis: role of nitric oxide. Pediatric Research. 59: 500-5. PMID 16549519 DOI: 10.1203/01.pdr.0000203094.27615.5f  0.84
2006 Feng J, El-Assal ON, Besner GE. Heparin-binding epidermal growth factor-like growth factor decreases the incidence of necrotizing enterocolitis in neonatal rats. Journal of Pediatric Surgery. 41: 144-9; discussion 14. PMID 16410124 DOI: 10.1016/j.jpedsurg.2005.10.018  0.84
2006 Feng J, Mehta VB, El-Assal ON, Wu D, Besner GE. Tissue distribution and plasma clearance of heparin-binding EGF-like growth factor (HB-EGF) in adult and newborn rats. Peptides. 27: 1589-96. PMID 16364500 DOI: 10.1016/j.peptides.2005.11.013  0.84
2005 Martin AE, Luquette MH, Besner GE. Timing, route, and dose of administration of heparin-binding epidermal growth factor-like growth factor in protection against intestinal ischemia-reperfusion injury. Journal of Pediatric Surgery. 40: 1741-7. PMID 16291163 DOI: 10.1016/j.jpedsurg.2005.07.064  0.84
2005 Feng J, El-Assal ON, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) and necrotizing enterocolitis. Seminars in Pediatric Surgery. 14: 167-74. PMID 16084404 DOI: 10.1053/j.sempedsurg.2005.05.005  0.84
2005 El-Assal ON, Besner GE. HB-EGF enhances restitution after intestinal ischemia/reperfusion via PI3K/Akt and MEK/ERK1/2 activation. Gastroenterology. 129: 609-25. PMID 16083716 DOI: 10.1016/j.gastro.2005.05.054  0.84
2005 Mehta VB, Besner GE. Heparin-binding epidermal growth factor-like growth factor inhibits cytokine-induced NF-kappa B activation and nitric oxide production via activation of the phosphatidylinositol 3-kinase pathway. Journal of Immunology (Baltimore, Md. : 1950). 175: 1911-8. PMID 16034135  0.84
2005 Provenzano AP, Besner GE, James PF, Harding PA. Heparin-binding EGF-like growth factor (HB-EGF) overexpression in transgenic mice downregulates insulin-like growth factor binding protein (IGFBP)-3 and -4 mRNA. Growth Factors (Chur, Switzerland). 23: 19-31. PMID 16019424 DOI: 10.1080/08977140512331344012  0.84
2005 Nowicki PT, Dunaway DJ, Nankervis CA, Giannone PJ, Giannnone PJ, Reber KM, Hammond SB, Besner GE, Caniano DA. Endothelin-1 in human intestine resected for necrotizing enterocolitis. The Journal of Pediatrics. 146: 805-10. PMID 15973323 DOI: 10.1016/j.jpeds.2005.01.046  0.84
2005 Besner GE, Bates GD, Boesel CP, Singh V, Welty SE, Corpron CA. Total absence of the small bowel in a premature neonate. Pediatric Surgery International. 21: 396-9. PMID 15809847 DOI: 10.1007/s00383-005-1386-9  0.84
2004 Corpron CA, Martin AE, Roberts G, Besner GE. The pediatric burn unit: a profit center. Journal of Pediatric Surgery. 39: 961-3; discussion 96. PMID 15185234 DOI: 10.1016/j.jpedsurg.2004.02.033  0.84
2004 Hedrick HL, Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD, Adzick NS. Sacrococcygeal teratoma: prenatal assessment, fetal intervention, and outcome. Journal of Pediatric Surgery. 39: 430-8; discussion 43. PMID 15017565 DOI: 10.1016/j.jpedsurg.2003.11.005  0.84
2004 El-Assal ON, Besner GE. Heparin-binding epidermal growth factor-like growth factor and intestinal ischemia-reperfusion injury. Seminars in Pediatric Surgery. 13: 2-10. PMID 14765365 DOI: 10.1053/j.sempedsurg.2003.09.002  0.84
2004 Besner GE, Gittes GK. Preface: Progress in Pediatric Surgical Research Seminars in Pediatric Surgery. 13: 1. DOI: 10.1053/j.sempedsurg.2003.09.001  0.84
2003 Mehta VB, Besner GE. Inhibition of NF-kappa B activation and its target genes by heparin-binding epidermal growth factor-like growth factor. Journal of Immunology (Baltimore, Md. : 1950). 171: 6014-22. PMID 14634113  0.84
2003 Xia G, Rachfal AW, Martin AE, Besner GE. Upregulation of endogenous heparin-binding EGF-like growth factor (HB-EGF) expression after intestinal ischemia/reperfusion injury. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 16: 57-63. PMID 12746188  0.84
2003 Xia G, Martin AE, Besner GE. Heparin-binding EGF-like growth factor downregulates expression of adhesion molecules and infiltration of inflammatory cells after intestinal ischemia/reperfusion injury. Journal of Pediatric Surgery. 38: 434-9. PMID 12632363 DOI: 10.1053/jpsu.2003.50075  0.84
2002 Kuhn MA, Xia G, Mehta VB, Glenn S, Michalsky MP, Besner GE. Heparin-binding EGF-like growth factor (HB-EGF) decreases oxygen free radical production in vitro and in vivo. Antioxidants & Redox Signaling. 4: 639-46. PMID 12230876 DOI: 10.1089/15230860260220148  0.84
2002 Xia G, Martin AE, Michalsky MP, Besner GE. Heparin-binding EGF-like growth factor preserves crypt cell proliferation and decreases bacterial translocation after intestinal ischemia/reperfusion injury. Journal of Pediatric Surgery. 37: 1081-7; discussion 1. PMID 12077776 DOI: 10.1053/jpsu.2002.33881  0.84
2002 Lara-Marquez ML, Mehta V, Michalsky MP, Fleming JB, Besner GE. Heparin-binding EGF-like growth factor down regulates proinflammatory cytokine-induced nitric oxide and inducible nitric oxide synthase production in intestinal epithelial cells. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 6: 142-52. PMID 11890738 DOI: 10.1006/niox.2001.0393  0.84
2002 Cribbs RK, Harding PA, Luquette MH, Besner GE. Endogenous production of heparin-binding EGF-like growth factor during murine partial-thickness burn wound healing. The Journal of Burn Care & Rehabilitation. 23: 116-25. PMID 11882801  0.84
2002 Michalsky MP, Lara-Marquez M, Chun L, Besner GE. Heparin-binding EGF-like growth factor is present in human amniotic fluid and breast milk. Journal of Pediatric Surgery. 37: 1-6. PMID 11781977 DOI: 10.1053/jpsu.2002.29415  0.84
2001 Davis-Fleische KM, Brigstock DR, Besner GE. Site-directed mutagenesis of heparin-binding EGF-like growth factor (HB-EGF): analysis of O-glycosylation sites and properties. Growth Factors (Chur, Switzerland). 19: 127-43. PMID 11769972  0.84
2001 Xia G, Lara-Marquez M, Luquette MH, Glenn S, Haque A, Besner GE. Heparin-binding EGF-like growth factor decreases inducible nitric oxide synthase and nitric oxide production after intestinal ischemia/reperfusion injury. Antioxidants & Redox Signaling. 3: 919-30. PMID 11761337 DOI: 10.1089/15230860152665073  0.84
2001 Hero B, Kremens B, Sudermann T, Haas RJ, Besner GE. Letter to the editor [3] Journal of Pediatric Surgery. 36: 1607-1608. PMID 11584425  0.84
2001 Michalsky MP, Kuhn A, Mehta V, Besner GE. Heparin-binding EGF-like growth factor decreases apoptosis in intestinal epithelial cells in vitro. Journal of Pediatric Surgery. 36: 1130-5. PMID 11479841 DOI: 10.1053/jpsu.2001.25730  0.84
2000 Vegunta RK, Morotti RA, Shiels WE, Rauck A, Besner GE. Collision tumors in children: a review of the literature and presentation of a rare case of mesoblastic nephroma and neuroblastoma in an infant. Journal of Pediatric Surgery. 35: 1359-61. PMID 10999699 DOI: 10.1053/jpsu.2000.9334  0.84
2000 Pillai SB, Bethel CA, Besner GE, Caniano DA, Cooney DR. Fall injuries in the pediatric population: safer and most cost-effective management. The Journal of Trauma. 48: 1048-50; discussion . PMID 10866249  0.84
2000 Coley BD, Mutabagani KH, Martin LC, Zumberge N, Cooney DR, Caniano DA, Besner GE, Groner JI, Shiels WE. Focused abdominal sonography for trauma (FAST) in children with blunt abdominal trauma. The Journal of Trauma. 48: 902-6. PMID 10823534  0.84
1999 Pillai SB, Hinman CE, Luquette MH, Nowicki PT, Besner GE. Heparin-binding epidermal growth factor-like growth factor protects rat intestine from ischemia/reperfusion injury. The Journal of Surgical Research. 87: 225-31. PMID 10600353 DOI: 10.1006/jsre.1999.5764  0.84
1999 McCarthy DW, Qualman SJ, Rudman DT, Wiet GJ, Besner GE. Herpetic tracheitis and brachial plexus neuropathy in a child with burns. The Journal of Burn Care & Rehabilitation. 20: 377-81. PMID 10501325  0.84
1999 Harding PA, Davis-Fleischer KM, Crissman-Combs MA, Miller MT, Brigstock DR, Besner GE. Induction of anchorage independent growth by heparin-binding EGF-like growth factor (HB-EGF). Growth Factors (Chur, Switzerland). 17: 49-61. PMID 10495962  0.84
1999 Mutabagani KH, Menke JA, McCoy KS, Besner GE. Bronchopexy for congenital bronchomalacia in the newborn. Journal of Pediatric Surgery. 34: 1300-3. PMID 10466621 DOI: 10.1016/S0022-3468(99)90177-X  0.84
1999 Mutabagani KH, Coley BD, Zumberge N, McCarthy DW, Besner GE, Caniano DA, Cooney DR. Preliminary experience with focused abdominal sonography for trauma (FAST) in children: is it useful? Journal of Pediatric Surgery. 34: 48-52; discussion 52. PMID 10022142 DOI: 10.1016/S0022-3468(99)90227-0  0.84
1998 Cribbs RK, Luquette MH, Besner GE. A standardized model of partial thickness scald burns in mice. The Journal of Surgical Research. 80: 69-74. PMID 9790817 DOI: 10.1006/jsre.1998.5340  0.84
1998 Pillai SB, Besner GE. Pediatric testicular problems. Pediatric Clinics of North America. 45: 813-30. PMID 9728188  0.84
1998 Besner GE, Klamar JE. Integra Artificial Skin as a useful adjunct in the treatment of purpura fulminans. The Journal of Burn Care & Rehabilitation. 19: 324-9. PMID 9710731  0.84
1998 Pillai SB, Luquette MH, Nowicki PT, Besner GE. Segmental intestinal ischemia: an improved method of producing small bowel injury. Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research. 11: 123-8. PMID 9700620  0.84
1998 Bethel CA, Mutabagani K, Hammond S, Besner GE, Caniano DA, Cooney DR. Nonteratomatous germ cell tumors in children. Journal of Pediatric Surgery. 33: 1122-6; discussion 1. PMID 9694107 DOI: 10.1016/S0022-3468(98)90544-9  0.84
1998 Pillai SB, Turman MA, Besner GE. Heparin-binding EGF-like growth factor is cytoprotective for intestinal epithelial cells exposed to hypoxia Journal of Pediatric Surgery. 33: 973-979. PMID 9694080 DOI: 10.1016/S0022-3468(98)90517-6  0.84
1998 Bethel CA, Luquette MH, Besner GE. Cystic degeneration of heterotopic pancreas. Pediatric Surgery International. 13: 428-30. PMID 9639636 DOI: 10.1007/s003830050358  0.84
1998 Cribbs RK, Luquette MH, Besner GE. Acceleration of partial-thickness burn wound healing with topical application of heparin-binding EGF-like growth factor (HB-EGF) Journal of Burn Care and Rehabilitation. 19: 95-101. PMID 9556308 DOI: 10.1097/00004630-199803000-00001  0.84
1998 Davis-Fleischer KM, Besner GE. Structure and function of heparin-binding EGF-like growth factor (HB-EGF) Frontiers in Bioscience : a Journal and Virtual Library. 3: d288-299. PMID 9473209  0.84
1997 Downing MT, Brigstock DR, Luquette MH, Crissman-Combs M, Besner GE. Immunohistochemical localization of heparin-binding epidermal growth factor-like growth factor in normal skin and skin cancers Histochemical Journal. 29: 735-744. PMID 9429077 DOI: 10.1023/A:1026417202351  0.84
1997 Zubair M, Besner GE. Pediatric electrical burns: Management strategies Burns. 23: 413-420. PMID 9426911 DOI: 10.1016/S0305-4179(97)00028-4  0.84
1997 Singh SP, Besner GE, Schauer GM. Pulmonary endodermal tumor resembling fetal lung: Report of a case in a 14-year-old girl Pediatric Pathology and Laboratory Medicine. 17: 951-958. PMID 9353835 DOI: 10.1080/107710497174408  0.84
1997 Downing MT, Hamoudi AB, Besner GE. Brain heterotopia: Choristoma of the back Pediatric Surgery International. 12: 183-185. PMID 9156853 DOI: 10.1007/s003830050098  0.84
1996 Besner GE, Qualman SJ, Gosche JR. Identification of a duplicated undescended testicle (polyorchia): an unexpected benefit of laparoscopic localization. Journal of Laparoendoscopic Surgery. 6: S107-14. PMID 8832940  0.84
1996 Davis KM, Brigstock DR, Johnson PR, Crissman-Combs MA, McCarthy DW, Downing MT, Besner GE. Production of glycosylated heparin-binding EGF-like growth factor in HeLa cells using vaccinia virus Protein Expression and Purification. 8: 57-67. PMID 8812835 DOI: 10.1006/prep.1996.0074  0.84
1996 Bensard DD, Beaver BL, Besner GE, Cooney DR. Small bowel injury in children after blunt abdominal trauma: is diagnostic delay important? The Journal of Trauma. 41: 476-83. PMID 8810966  0.84
1996 Harding PA, Brigstock DR, Shen L, Crissman-Combs MA, Besner GE. Characterization of the gene encoding murine heparin-binding epidermal growth factor-like growth factor Gene. 169: 291-292. PMID 8647467 DOI: 10.1016/0378-1119(95)00861-6  0.84
1996 McCarthy DW, Downing MT, Brigstock DR, Luquette MH, Brown KD, Abad MS, Besner GE. Production of heparin-binding epidermal growth factor-like growth factor (HB-EGF) at sites of thermal injury in pediatric patients Journal of Investigative Dermatology. 106: 49-56. PMID 8592081  0.84
1996 McCarthy DW, Besner GE, Gosche JR, Qualman SP, Chan DP, Olson TA. Retroperitoneal yolk sac tumor with spinal cord compression and intracardiac extension International Journal of Pediatric Hematology/Oncology. 3: 157-161.  0.84
1995 Vegunta RK, Cooney DR, Downing MT, Besner GE, Brigstock DR. Unique protein expression by the TBJ clonal derivative of C1300 murine neuroblastoma. Journal of Pediatric Surgery. 30: 1668-72. PMID 8749920  0.84
1995 Martinez DA, O'Dorisio MS, O'Dorisio TM, Qualman SJ, Caniano DA, Teich S, Besner GE, King DR. Intraoperative detection and resection of occult neuroblastoma: a technique exploiting somatostatin receptor expression. Journal of Pediatric Surgery. 30: 1580-9. PMID 8583329  0.84
1995 Mutabagani KH, Beaver BL, Cooney DR, Besner GE. Penetrating neck trauma in children: a reappraisal. Journal of Pediatric Surgery. 30: 341-4. PMID 7738762  0.84
1995 Kim GY, Besner GE, Steffen CL, McCarthy DW, Downing MT, Luquette MH, Abad MS, Brigstock DR. Purification of heparin-binding epidermal growth factor-like growth factor from pig uterine luminal flushings, and its production by endometrial tissues Biology of Reproduction. 52: 561-571. PMID 7538797 DOI: 10.1095/biolreprod52.3.561  0.84
1994 McCarthy DW, Qualman S, Besner GE. Absent intestinal musculature: Anatomic evidence of an embryonic origin of the lesion Journal of Pediatric Surgery. 29: 1476-1478. PMID 7844725 DOI: 10.1016/0022-3468(94)90148-1  0.84
1993 Besner GE, Fisher JE, Mazzadri FC, Karp MP, Jewett TC, Cooney DR. Teratoma in a thyroglossal duct cyst: A rare occurence Pediatric Surgery International. 8: 66-70. DOI: 10.1007/BF02353009  0.84
1992 Glick PL, Leach CL, Besner GE, Egan EA, Morin FC, Malanowska-Kantoch A, Robinson LK, Brody A, Lele AS, McDonnell M. Pathophysiology of congenital diaphragmatic hernia. III: Exogenous surfactant therapy for the high-risk neonate with CDH. Journal of Pediatric Surgery. 27: 866-9. PMID 1640336 DOI: 10.1016/0022-3468(92)90386-L  0.84
1992 Higashiyama S, Lau K, Besner GE, Abraham JA, Klagsbrun M. Structure of heparin-binding EGF-like growth factor: Multiple forms, primary structure, and glycosylation of the mature protein Journal of Biological Chemistry. 267: 6205-6212. PMID 1556128  0.84
1992 Besner GE, Glick PL, Karp MP, Wang WC, Lobe TE, White CR, Cooney DR. Recombinant human granulocyte colony-stimulating factor promotes wound healing in a patient with congenital neutropenia. Journal of Pediatric Surgery. 27: 288-90; discussion 2. PMID 1380074 DOI: 10.1016/0022-3468(92)90848-2  0.84
1992 Besner GE, Whelton D, Crissman-Combs MA, Steffen CL, Kim GY, Brigstock DR. Interaction of heparin-binding EGF-like growth factor (HB-EGF) with the epidermal growth factor receptor: Modulation by heparin, heparinase, or synthetic heparin-binding HB-EGF fragments Growth Factors. 7: 289-296. PMID 1306684 DOI: 10.3109/08977199209046411  0.84
1991 Besner GE, Klagsbrun M. Macrophages secrete a heparin-binding inhibitor of endothelial cell growth Microvascular Research. 42: 187-197. PMID 1719354 DOI: 10.1016/0026-2862(91)90086-Q  0.84
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