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Ke Xia, Ph.D. - Publications

Affiliations: 
2009 Rensselaer Polytechnic Institute, Troy, NY, United States 
Area:
Protein Folding/Misfolding
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64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yang J, Song Y, Jin W, Xia K, Burnett GC, Qiao W, Bates JT, Pomin VH, Wang C, Qiao M, Linhardt RJ, Dordick JS, Zhang F. Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin. Viruses. 16. PMID 38400013 DOI: 10.3390/v16020237  0.339
2023 Gouveia M, Schmidt C, Basilio PG, Aveiro SS, Domingues P, Xia K, Colón W, Vitorino R, Ferreira R, Santos M, Vieira SI, Ribeiro F. Exercise training decreases the load and changes the content of circulating SDS-resistant protein aggregates in patients with heart failure with reduced ejection fraction. Molecular and Cellular Biochemistry. PMID 37902886 DOI: 10.1007/s11010-023-04884-z  0.599
2023 Hoffman E, Song Y, Zhang F, Asarian L, Downs I, Young B, Han X, Ouyang Y, Xia K, Linhardt RJ, Weiss DJ. Regional and Disease-Specific Glycosaminoglycan Composition and Function in Decellularized Human Lung Extracellular Matrix. Acta Biomaterialia. PMID 37433361 DOI: 10.1016/j.actbio.2023.06.043  0.505
2023 He P, Xia K, Song Y, Tandon R, Channappanavar R, Zhang F, Linhardt RJ. Synthesis of multivalent sialyllactose-conjugated PAMAM dendrimers: Binding to SARS-CoV-2 spike protein and influenza hemagglutinin. International Journal of Biological Macromolecules. 246: 125714. PMID 37423440 DOI: 10.1016/j.ijbiomac.2023.125714  0.518
2023 He P, Shi D, Li Y, Xia K, Kim SB, Dwivedi R, Farrag M, Pomin VH, Linhardt RJ, Dordick JS, Zhang F. SPR Sensor-Based Analysis of the Inhibition of Marine Sulfated Glycans on Interactions between Monkeypox Virus Proteins and Glycosaminoglycans. Marine Drugs. 21. PMID 37233458 DOI: 10.3390/md21050264  0.531
2023 Al Mahbuba D, Masuko S, Wang S, Syangtan D, Kang JS, Song Y, Shin TW, Xia K, Zhang F, Linhardt RJ, Boyden ES, Kiessling LL. Dynamic Changes in Heparan Sulfate Nanostructure in Human Pluripotent Stem Cell Differentiation. Acs Nano. PMID 37042659 DOI: 10.1021/acsnano.2c10072  0.667
2023 Song Y, Kouta A, Cera LM, Xia K, Zhang F, Kraemer R, Fareed J, Linhardt RJ, Jeske W. Absolute pharmacokinetics of heparin in primates. Carbohydrate Polymers. 311: 120779. PMID 37028882 DOI: 10.1016/j.carbpol.2023.120779  0.54
2022 Hashimoto JG, Singer ML, Goeke CM, Zhang F, Song Y, Xia K, Linhardt RJ, Guizzetti M. Sex differences in hippocampal structural plasticity and glycosaminoglycan disaccharide levels after neonatal handling. Experimental Neurology. 361: 114313. PMID 36572372 DOI: 10.1016/j.expneurol.2022.114313  0.48
2022 He P, Zhang X, Xia K, Green DE, Baytas S, Xu Y, Pham T, Liu J, Zhang F, Almond A, Linhardt RJ, DeAngelis PL. Chemoenzymatic synthesis of sulfur-linked sugar polymers as heparanase inhibitors. Nature Communications. 13: 7438. PMID 36460670 DOI: 10.1038/s41467-022-34788-3  0.783
2022 Gandy LA, Canning AJ, Lou H, Xia K, He P, Su G, Cairns T, Liu J, Zhang F, Linhardt RJ, Cohen G, Wang C. Molecular determinants of the interaction between HSV-1 glycoprotein D and heparan sulfate. Frontiers in Molecular Biosciences. 9: 1043713. PMID 36419932 DOI: 10.3389/fmolb.2022.1043713  0.587
2022 Patil NP, Gómez-Hernández A, Zhang F, Cancel L, Feng X, Yan L, Xia K, Takematsu E, Yang EY, Le V, Fisher ME, Gonzalez-Rodriguez A, Garcia-Monzon C, Tunnell J, Tarbell J, et al. Rhamnan sulfate reduces atherosclerotic plaque formation and vascular inflammation. Biomaterials. 291: 121865. PMID 36332287 DOI: 10.1016/j.biomaterials.2022.121865  0.478
2022 Gouveia M, Schmidt C, Teixeira M, Lopes M, Aveiro SS, Domingues P, Xia K, Colón W, Vitorino R, Ferreira R, Santos M, Vieira S, Ribeiro F. Characterization of Plasma SDS-Protein Aggregation Profile of Patients with Heart Failure with Preserved Ejection Fraction. Journal of Cardiovascular Translational Research. PMID 36271180 DOI: 10.1007/s12265-022-10334-w  0.618
2022 Yu Y, Fu L, He P, Xia K, Varghese S, Dordick J, Wang H, Zhang F, Linhardt RJ. Enzymatic synthesis of low molecular weight heparins from N-sulfo heparosan depolymerized by heparanase or heparin lyase. Carbohydrate Polymers. 295: 119825. PMID 35988993 DOI: 10.1016/j.carbpol.2022.119825  0.732
2022 Kaur G, Song Y, Xia K, McCarthy K, Zhang F, Linhardt RJ, Harris NR. Effect of high glucose on glycosaminoglycans in cultured retinal endothelial cells and rat retina. Glycobiology. PMID 35552402 DOI: 10.1093/glycob/cwac029  0.505
2022 Kim SB, Zoepfl M, Samanta P, Zhang F, Xia K, Thara R, Linhardt RJ, Doerksen RJ, McVoy MA, Pomin VH. Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties. The Journal of Biological Chemistry. 101856. PMID 35337800 DOI: 10.1016/j.jbc.2022.101856  0.592
2022 Ahat E, Song Y, Xia K, Reid W, Li J, Bui S, Zhang F, Linhardt RJ, Wang Y. GRASP depletion-mediated Golgi fragmentation impairs glycosaminoglycan synthesis, sulfation, and secretion. Cellular and Molecular Life Sciences : Cmls. 79: 199. PMID 35312866 DOI: 10.1007/s00018-022-04223-3  0.524
2022 Yu Y, Fu L, He P, Xia K, Varghese S, Wang H, Zhang F, Dordick J, Linhardt RJ. Chemobiocatalytic Synthesis of a Low-Molecular-Weight Heparin. Acs Chemical Biology. PMID 35201757 DOI: 10.1021/acschembio.1c00928  0.721
2021 Ning Z, Lang K, Xia K, Linhardt RJ, Gross RA. Lipase-Catalyzed Synthesis and Characterization of Poly(glycerol sebacate). Biomacromolecules. PMID 34936341 DOI: 10.1021/acs.biomac.1c01351  0.773
2021 Yan L, Song Y, Xia K, He P, Zhang F, Chen S, Pouliot R, Weiss DJ, Tandon R, Bates JT, Ederer DR, Mitra D, Sharma P, Davis A, Linhardt RJ. Heparan sulfates from bat and human lung and their binding to the spike protein of SARS-CoV-2 virus. Carbohydrate Polymers. 260: 117797. PMID 33712145 DOI: 10.1016/j.carbpol.2021.117797  0.515
2021 Xia K, Hagan JT, Fu L, Sheetz BS, Bhattacharya S, Zhang F, Dwyer JR, Linhardt RJ. Synthetic heparan sulfate standards and machine learning facilitate the development of solid-state nanopore analysis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33688052 DOI: 10.1073/pnas.2022806118  0.581
2021 Badri A, Williams A, Awofiranye A, Datta P, Xia K, He W, Fraser K, Dordick JS, Linhardt RJ, Koffas MAG. Complete biosynthesis of a sulfated chondroitin in Escherichia coli. Nature Communications. 12: 1389. PMID 33654100 DOI: 10.1038/s41467-021-21692-5  0.653
2021 Baytas SN, Varghese SS, Jin W, Yu Y, He P, Douaisi M, Zhang F, Brodfuehrer P, Xia K, Dordick JS, Linhardt RJ. Preparation of Low Molecular Weight Heparin from a Remodeled Bovine Intestinal Heparin. Journal of Medicinal Chemistry. PMID 33586962 DOI: 10.1021/acs.jmedchem.0c02019  0.772
2021 Garrudo FFF, Mikael PE, Xia K, Silva JC, Ouyang Y, Chapman CA, Hoffman PR, Yu Y, Han X, Rodrigues CAV, Cabral JMS, Morgado J, Ferreira FC, Linhardt RJ. The effect of electrospun scaffolds on the glycosaminoglycan profile of differentiating neural stem cells. Biochimie. PMID 33422570 DOI: 10.1016/j.biochi.2021.01.001  0.77
2020 Yan L, Fu L, Xia K, Chen S, Zhang F, Dordick JS, Linhardt RJ. A Revised Structure for the Glycolipid Terminus of K5 Heparosan Capsular Polysaccharide. Biomolecules. 10. PMID 33171953 DOI: 10.3390/biom10111516  0.568
2020 Qiao M, Lin L, Xia K, Li J, Zhang X, Linhardt RJ. Recent advances in biotechnology for heparin and heparan sulfate analysis. Talanta. 219: 121270. PMID 32887160 DOI: 10.1016/J.Talanta.2020.121270  0.666
2020 Awofiranye AE, Baytas SN, Xia K, Badri A, He W, Varki A, Koffas M, Linhardt RJ. N-glycolyl chondroitin synthesis using metabolically engineered E. coli. Amb Express. 10: 144. PMID 32803432 DOI: 10.1186/S13568-020-01084-6  0.771
2020 Li J, Sparkenbaugh EM, Su G, Zhang F, Xu Y, Xia K, He P, Baytas S, Pechauer S, Padmanabhan A, Linhardt RJ, Pawlinski R, Liu J. Enzymatic Synthesis of Chondroitin Sulfate E to Attenuate Bacteria Lipopolysaccharide-Induced Organ Damage. Acs Central Science. 6: 1199-1207. PMID 32724854 DOI: 10.1021/Acscentsci.0C00712  0.759
2020 Bhattacharyya S, Feferman L, Han X, Xia K, Zhang F, Linhardt RJ, Tobacman JK. Increased CHST15 follows decline in arylsulfatase B (ARSB) and disinhibition of non-canonical WNT signaling: potential impact on epithelial and mesenchymal identity. Oncotarget. 11: 2327-2344. PMID 32595831 DOI: 10.18632/Oncotarget.27634  0.547
2020 Vaidyanathan D, Xia K, Yu Y, Linhardt RJ, Dordick JS. Polysaccharide Sequence Influences the Specificity and Catalytic Activity of Glucuronyl C5-Epimerase. Biochemistry. PMID 32579846 DOI: 10.1021/Acs.Biochem.0C00419  0.623
2020 Jin W, Jiang D, Zhang W, Wang C, Xia K, Zhang F, Linhardt RJ. Interactions of fibroblast growth factors with sulfated galactofucan from Saccharina japonica. International Journal of Biological Macromolecules. PMID 32464202 DOI: 10.1016/J.Ijbiomac.2020.05.183  0.574
2020 Yan L, Xia K, Yu Y, Miliakos A, Chaturvedi S, Zhang F, Chen S, Chaturvedi V, Linhardt RJ. Unique cell surface mannan of yeast pathogen Candida auris with selective binding to IgG. Acs Infectious Diseases. PMID 32233507 DOI: 10.1021/Acsinfecdis.9B00450  0.695
2020 Silva JC, Carvalho MS, Xia K, Cabral JMS, da Silva CL, Ferreira FC, Vashishth D, Linhardt RJ. Glycosaminoglycan disaccharide compositional analysis of cell-derived extracellular matrices using liquid chromatography-tandem mass spectrometry. Methods in Cell Biology. 156: 85-106. PMID 32222228 DOI: 10.1016/Bs.Mcb.2019.11.017  0.625
2020 Arnold K, Xu Y, Sparkenbaugh EM, Li M, Han X, Zhang X, Xia K, Piegore M, Zhang F, Zhang X, Henderson M, Pagadala V, Su G, Tan L, Park PW, et al. Design of anti-inflammatory heparan sulfate to protect against acetaminophen-induced acute liver failure. Science Translational Medicine. 12. PMID 32188725 DOI: 10.1126/Scitranslmed.Aav8075  0.637
2020 Silva JC, Han X, Silva TP, Xia K, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ. Glycosaminoglycan remodeling during chondrogenic differentiation of human bone marrow-/synovial-derived mesenchymal stem/stromal cells under normoxia and hypoxia. Glycoconjugate Journal. PMID 32086666 DOI: 10.1007/S10719-020-09911-5  0.777
2020 Colon W, Rugaber EG, Xia K. Proteomics Analyses of Kinetic Stability: from Molecular to Organism Longevity Biophysical Journal. 118: 181a. DOI: 10.1016/J.Bpj.2019.11.1104  0.644
2019 Uhl FE, Zhang F, Pouliot RA, Uriarte JJ, Enes SR, Han X, Ouyang Y, Xia K, Westergren-Thorsson G, Malmström A, Hallgren O, Linhardt RJ, Weiss DJ. Functional Role of Glycosaminoglycans in Decellularized Lung Extracellular Matrix. Acta Biomaterialia. PMID 31751810 DOI: 10.1016/J.Actbio.2019.11.029  0.563
2019 Lin L, Yu Y, Zhang F, Xia K, Zhang X, Linhardt RJ. Bottom-up and top-down profiling of pentosan polysulfate. The Analyst. PMID 31287456 DOI: 10.1039/C9An01006H  0.777
2019 Badri A, Williams A, Xia K, Linhardt RJ, Koffas MAG. Increased 3'-phosphoadenosine-5'-phosphosulfate levels in engineered Escherichia coli cell lysate facilitates in vitro synthesis of Chondroitin Sulfate A. Biotechnology Journal. e1800436. PMID 31180182 DOI: 10.1002/Biot.201800436  0.422
2019 Yu Y, Williams A, Zhang X, Fu L, Xia K, Xu Y, Zhang F, Liu J, Koffas M, Linhardt RJ. Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei. Glycobiology. PMID 31143933 DOI: 10.1093/Glycob/Cwz039  0.758
2019 Zhang X, Han X, Xia K, Xu Y, Yang Y, Oshima K, Haeger SM, Perez MJ, McMurtry SA, Hippensteel JA, Ford JA, Herson PS, Liu J, Schmidt EP, Linhardt RJ. Circulating heparin oligosaccharides rapidly target the hippocampus in sepsis, potentially impacting cognitive functions. Proceedings of the National Academy of Sciences of the United States of America. PMID 31010931 DOI: 10.1073/Pnas.1902227116  0.534
2019 Chen J, Yu Y, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Jin C, Jin Y, Yao Y, Xia K, Zhang F, Chen S, Ye X, Linhardt RJ. Comparison of Low-Molecular-Weight Heparins Prepared From Ovine Heparins With Enoxaparin. Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. 25: 1076029619840701. PMID 30987427 DOI: 10.1177/1076029619840701  0.7
2019 Thibeault J, Patrick J, Martin A, Ortiz-Perez B, Hill S, Zhang S, Xia K, Colón W. Sarkosyl: A milder detergent than SDS for identifying proteins with moderately high hyperstability using gel electrophoresis. Analytical Biochemistry. PMID 30779907 DOI: 10.1016/J.Ab.2019.02.008  0.786
2019 Silva JC, Carvalho MS, Han X, Xia K, Mikael PE, Cabral JMS, Ferreira FC, Linhardt RJ. Compositional and structural analysis of glycosaminoglycans in cell-derived extracellular matrices. Glycoconjugate Journal. PMID 30637588 DOI: 10.1007/S10719-019-09858-2  0.784
2019 Ouyang Y, Yu Y, Zhang F, Chen J, Han X, Xia K, Yao Y, Zhang Z, Linhardt RJ. Non-Anticoagulant Low Molecular Weight Heparins for Pharmaceutical Applications. Journal of Medicinal Chemistry. PMID 30608147 DOI: 10.1021/Acs.Jmedchem.8B01551  0.773
2019 Sarnaik A, Abernathy MH, Han X, Ouyang Y, Xia K, Chen Y, Cress B, Zhang F, Lali A, Pandit R, Linhardt RJ, Tang YJ, Koffas MA. Metabolic engineering of cyanobacteria for photoautotrophic production of heparosan, a pharmaceutical precursor of heparin Algal Research. 37: 57-63. DOI: 10.1016/J.Algal.2018.11.010  0.748
2019 Badri A, Williams A, Xia K, Linhardt RJ, Koffas MAG. Outside Back Cover: Biotechnology Journal 9/2019 Biotechnology Journal. 14: 1970095. DOI: 10.1002/Biot.201970095  0.329
2018 Mikael P, Willard C, Koyee A, Barlao CG, Liu X, Han X, Ouyang Y, Xia K, Linhardt RJ, Dordick JS. Remodeling of Glycosaminoglycans During Differentiation of Adult Human Bone Mesenchymal Stromal Cells toward Hepatocytes. Stem Cells and Development. PMID 30572803 DOI: 10.1089/Scd.2018.0197  0.768
2018 Yu Y, Zhang F, Colón W, Linhardt RJ, Xia K. Glycosaminoglycans in human cerebrospinal fluid determined by LC-MS/MS MRM. Analytical Biochemistry. PMID 30571946 DOI: 10.1016/J.Ab.2018.12.013  0.763
2018 Ouyang Y, Han X, Xia Q, Chen J, Velagapudi S, Xia K, Zhang Z, Linhardt RJ. Negative-Ion Mode Capillary Isoelectric Focusing-Mass Spectrometry for Charge-Based Separation of Acidic Oligosaccharides. Analytical Chemistry. PMID 30516363 DOI: 10.1021/Acs.Analchem.8B03500  0.61
2018 Ouyang Y, Han X, Yu Y, Chen J, Fu L, Zhang F, Linhardt RJ, Fareed J, Hoppensteadt D, Jeske W, Kouta A, Zhang Z, Xia K. Chemometric analysis of porcine, bovine and ovine heparins. Journal of Pharmaceutical and Biomedical Analysis. 164: 345-352. PMID 30428408 DOI: 10.1016/J.Jpba.2018.10.052  0.775
2018 Kizer M, Li P, Cress BF, Lin L, Jing TT, Zhang X, Xia K, Linhardt RJ, Wang X. RNA Aptamers with Specificity for Heparosan and Chondroitin Glycosaminoglycans. Acs Omega. 3: 13667-13675. PMID 30411046 DOI: 10.1021/acsomega.8b01853  0.752
2018 Zhang X, Xia K, Lin L, Zhang F, Yu Y, St Ange K, Han X, Edsinger E, Sohn JJ, Linhardt RJ. Structural and functional components of the skate sensory organ ampullae of Lorenzini. Acs Chemical Biology. PMID 29708722 DOI: 10.1021/Acschembio.8B00335  0.771
2017 Colon W, Church J, Sen J, Thibeault J, Trasatti HS, Xia K. Biological roles of protein kinetic stability. Biochemistry. PMID 29087706 DOI: 10.1021/Acs.Biochem.7B00942  0.677
2017 Thibeault J, Church J, Ortiz-Perez B, Addo S, Hill S, Khalil A, Young M, Xia K, Colón W. Analyzing bean extracts using time-dependent SDS trapping to quantify the kinetic stability of phaseolin proteins. Biochemical and Biophysical Research Communications. PMID 28774556 DOI: 10.1016/J.Bbrc.2017.07.166  0.671
2017 Gouveia M, Xia K, Colón W, Vieira SI, Ribeiro F. Protein aggregation, cardiovascular diseases, and exercise training: where do we stand? Ageing Research Reviews. PMID 28757291 DOI: 10.1016/J.Arr.2017.07.005  0.625
2017 Colón W, Xia K, Church J, Sen J, Thibeault J, Trasatti HS. Biological Roles of Protein Hyperstability: Implications for Biotechnology Biophysical Journal. 112: 56a. DOI: 10.1016/J.Bpj.2016.11.340  0.688
2016 Xia K, Pittelli S, Church J, Colon W. Kinetic Stability of Proteins in Beans and Peas: Implications for Protein Digestibility, Seed Germination, and Plant Adaptation. Journal of Agricultural and Food Chemistry. PMID 27643830 DOI: 10.1021/Acs.Jafc.6B01965  0.677
2016 Xia K, Trasatti H, Wymer JP, Colón W. Increased levels of hyper-stable protein aggregates in plasma of older adults. Age (Dordrecht, Netherlands). 38: 56. PMID 27179971 DOI: 10.1007/S11357-016-9919-9  0.657
2015 Broom A, Ma SM, Xia K, Rafalia H, Trainor K, Colón W, Gosavi S, Meiering EM. Designed protein reveals structural determinants of extreme kinetic stability. Proceedings of the National Academy of Sciences of the United States of America. PMID 26554002 DOI: 10.1073/Pnas.1510748112  0.668
2015 Xia K, Wilcox J, Kobovitch K, Ortiz B, Khalil A, Colon W. Proteomics-Level Identification of Degradation-Resistant Proteins Provide Insight about their Potential Roles in Organismal Adaptation to Stress Biophysical Journal. 108: 501a. DOI: 10.1016/J.Bpj.2014.11.2745  0.681
2012 Xia K, Zhang S, Bathrick B, Liu S, Garcia Y, Colón W. Quantifying the kinetic stability of hyperstable proteins via time-dependent SDS trapping. Biochemistry. 51: 100-7. PMID 22106876 DOI: 10.1021/Bi201362Z  0.787
2010 Xia K, Zhang S, Solina BA, Barquera B, Colón W. Do prokaryotes have more kinetically stable proteins than eukaryotic organisms? Biochemistry. 49: 7239-41. PMID 20677776 DOI: 10.1021/Bi1010877  0.777
2010 Zhang S, Xia K, Chung WK, Cramer SM, Colón W. Identifying kinetically stable proteins with capillary electrophoresis. Protein Science : a Publication of the Protein Society. 19: 888-92. PMID 20091769 DOI: 10.1002/Pro.336  0.79
2007 Xia K, Manning M, Hesham H, Lin Q, Bystroff C, Colón W. Identifying the subproteome of kinetically stable proteins via diagonal 2D SDS/PAGE. Proceedings of the National Academy of Sciences of the United States of America. 104: 17329-34. PMID 17956990 DOI: 10.1073/Pnas.0705417104  0.769
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