| Year |
Citation |
Score |
| 2017 |
Le Moigne R, Aftab BT, Djakovic S, Dhimolea E, Valle E, Murnane M, King EM, Soriano F, Menon MK, Wu ZY, Wong ST, Lee GJ, Yao B, Wiita AP, Lam C, et al. The p97 inhibitor CB-5083 is a unique disrupter of protein homeostasis in models of Multiple Myeloma. Molecular Cancer Therapeutics. PMID 28878026 DOI: 10.1158/1535-7163.Mct-17-0233 |
0.328 |
|
| 2016 |
Menon M, Soriano F, Wong S, Valle E, Djakovic S, Kumar B, Yao B, Madriaga A, Wu T, Rice J, Wang J, Cesano A, Shawver L, Zhou H, Wustrow D, et al. Abstract 4541: Utilization of K48 poly-ubiquitin modulation as a biomarker of target engagement for a protein homeostasis inhibitor in the clinic: Preclinical validation with CB-5083, a first-in-class inhibitor of the AAA ATPase p97 Cancer Research. 76: 4541-4541. DOI: 10.1158/1538-7445.Am2016-4541 |
0.313 |
|
| 2015 |
Zhou HJ, Wang J, Yao B, Wong S, Djakovic S, Kumar B, Rice J, Valle E, Soriano F, Menon MK, Madriaga A, Kissvonsoly S, Kumar A, Parlati F, Yakes MF, et al. Discovery of a First-in-Class, Potent, Selective and Orally Bioavailable Inhibitor of the p97 AAA ATPase (CB-5083). Journal of Medicinal Chemistry. PMID 26565666 DOI: 10.1021/acs.jmedchem.5b01346 |
0.339 |
|
| 2015 |
Anderson DJ, Le Moigne R, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Kiss von Soly S, Madriaga A, Soriano F, Menon MK, Wu ZY, Kampmann M, et al. Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis. Cancer Cell. 28: 653-65. PMID 26555175 DOI: 10.1016/J.Ccell.2015.10.002 |
0.379 |
|
| 2015 |
Yin Y, Djakovic S, Marsters S, Tien J, Peng J, Tremayne J, Lee G, Neve RM, Wu Y, Merchant M, Ashkenazi A, Carter PJ. Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Anti-tumor Activity. Molecular Cancer Therapeutics. PMID 26269606 DOI: 10.1158/1535-7163.Mct-14-1050 |
0.39 |
|
| 2015 |
Nawrocki ST, Han Y, Moigne RL, Visconte V, Przychodzen B, Rolfe M, Djakovic S, Anderson D, Wustrow D, Zhou H, Wong S, Advani A, Carraway HE, Maciejewski JP, Sekeres MA, et al. Activation of the Unfolded Protein Response with the First-in-Class P97 Inhibitor CB-5083 Induces Stable Disease Regression and Overcomes Ara-C Resistance in AML Blood. 126: 1350-1350. DOI: 10.1182/Blood.V126.23.1350.1350 |
0.355 |
|
| 2015 |
Anderson DJ, Moigne RL, Djakovic S, Kumar B, Rice J, Wong S, Wang J, Yao B, Valle E, Menon M, Soly SKv, Madriaga A, Sorlano F, Longhi M, Cesano A, et al. Abstract DDT02-01: Inhibition of the AAA-ATPase p97 with the first in class inhibitor CB-5083 as a novel approach to treat cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Ddt02-01 |
0.354 |
|
| 2014 |
Dubinsky AN, Dastidar SG, Hsu CL, Zahra R, Djakovic SN, Duarte S, Esau CC, Spencer B, Ashe TD, Fischer KM, MacKenna DA, Sopher BL, Masliah E, Gaasterland T, Chau BN, et al. Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy. Cell Metabolism. 20: 626-38. PMID 25295787 DOI: 10.1016/J.Cmet.2014.09.001 |
0.57 |
|
| 2014 |
Aftab BT, Anderson DJ, Le Moigne R, Djakovic S, Dhimolea E, Murnane M, King E, Rice J, Wong S, Kumar B, Valle E, Menon M, Kiss von Soly S, Wang J, Yao B, et al. Pre-Clinical Activity of the Novel, First-in-Class p97 Inhibitor, CB-5083, in Multiple Myeloma Blood. 124: 4701-4701. DOI: 10.1182/Blood.V124.21.4701.4701 |
0.364 |
|
| 2014 |
Tohme R, Moigne RL, Przychodzen BP, Han Y, Rolfe M, Carraway HE, Djakovic S, Anderson D, Wustrow D, Zhou H, Wong S, Kelly KR, Saunthararajah Y, Advani AS, Maciejewski JP, et al. Inhibition of p97 with the First-in-Class Small Molecule CB-5083: A Novel Strategy for Acute Myeloid Leukemia Therapy Blood. 124: 3766-3766. DOI: 10.1182/Blood.V124.21.3766.3766 |
0.365 |
|
| 2014 |
Moigne RL, Wong S, Soriano F, Valle E, Anderson DJ, Djakovic S, Menon M, Yao B, Rice J, Wang J, Soly SKV, Kumar B, Chesi M, Bergsagel PL, Zhou H, et al. Abstract 951: CB-5083 is a novel first in class p97 inhibitor that disrupts cellular protein homeostasis and demonstrates anti-tumor activity in solid and hematological models Cancer Research. 74: 951-951. DOI: 10.1158/1538-7445.Am2014-951 |
0.369 |
|
| 2013 |
Djakovic SN, Anderson DJ, Soly SKv, Moigne RL, Rice J, Rolfe M, Soriano F, Valle E, Wang J, Wong S, Wustrow D, Yakes FM, Yao B, Zhou H. Abstract C188: Novel small molecule inhibitors of p97 disrupt cellular protein homeostasis and demonstrate anti-tumor activity in solid and hematological models. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C188 |
0.348 |
|
| 2012 |
Djakovic SN, Marquez-Lona EM, Jakawich SK, Wright R, Chu C, Sutton MA, Patrick GN. Phosphorylation of Rpt6 regulates synaptic strength in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5126-31. PMID 22496558 DOI: 10.1523/Jneurosci.4427-11.2012 |
0.613 |
|
| 2010 |
Jakawich SK, Neely RM, Djakovic SN, Patrick GN, Sutton MA. An essential postsynaptic role for the ubiquitin proteasome system in slow homeostatic synaptic plasticity in cultured hippocampal neurons. Neuroscience. 171: 1016-31. PMID 20888892 DOI: 10.1016/J.Neuroscience.2010.09.061 |
0.609 |
|
| 2009 |
Djakovic SN, Schwarz LA, Barylko B, DeMartino GN, Patrick GN. Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II. The Journal of Biological Chemistry. 284: 26655-65. PMID 19638347 DOI: 10.1074/jbc.M109.021956 |
0.762 |
|
| 2009 |
Cartier AE, Djakovic SN, Salehi A, Wilson SM, Masliah E, Patrick GN. Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7857-68. PMID 19535597 DOI: 10.1523/Jneurosci.1817-09.2009 |
0.689 |
|
| 2009 |
Kerjan G, Koizumi H, Han EB, Dubé CM, Djakovic SN, Patrick GN, Baram TZ, Heinemann SF, Gleeson JG. Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures. Proceedings of the National Academy of Sciences of the United States of America. 106: 6766-71. PMID 19342486 DOI: 10.1073/Pnas.0812687106 |
0.641 |
|
| 2008 |
Dyachok J, Shao MR, Vaughn K, Bowling A, Facette M, Djakovic S, Clark L, Smith L. Plasma membrane-associated SCAR complex subunits promote cortical F-actin accumulation and normal growth characteristics in Arabidopsis roots. Molecular Plant. 1: 990-1006. PMID 19825598 DOI: 10.1093/Mp/Ssn059 |
0.497 |
|
| 2006 |
Djakovic S, Dyachok J, Burke M, Frank MJ, Smith LG. BRICK1/HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis. Development (Cambridge, England). 133: 1091-100. PMID 16481352 DOI: 10.1242/dev.02280 |
0.51 |
|
| 2004 |
Frank M, Egile C, Dyachok J, Djakovic S, Nolasco M, Li R, Smith LG. Activation of Arp2/3 complex-dependent actin polymerization by plant proteins distantly related to Scar/WAVE. Proceedings of the National Academy of Sciences of the United States of America. 101: 16379-84. PMID 15534215 DOI: 10.1073/Pnas.0407392101 |
0.529 |
|
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