James W. Fawcett - Publications

Affiliations: 
Brain Repair Centre University of Cambridge, Cambridge, England, United Kingdom 

292 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Carnicer-Lombarte A, Barone DG, Wronowski F, Malliaras GG, Fawcett JW, Franze K. Regenerative capacity of neural tissue scales with changes in tissue mechanics post injury. Biomaterials. 303: 122393. PMID 37977006 DOI: 10.1016/j.biomaterials.2023.122393  0.53
2023 Cheah M, Cheng Y, Petrova V, Cimpean A, Jendelova P, Swarup V, Woolf CJ, Geschwind DH, Fawcett JW. Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 37277179 DOI: 10.1523/JNEUROSCI.2076-22.2023  0.851
2023 Nieuwenhuis B, Laperrousaz E, Tribble JR, Verhaagen J, Fawcett JW, Martin KR, Williams PA, Osborne A. Improving adeno-associated viral (AAV) vector-mediated transgene expression in retinal ganglion cells: comparison of five promoters. Gene Therapy. PMID 36635457 DOI: 10.1038/s41434-022-00380-z  0.728
2022 Ruzicka J, Dalecka M, Safrankova K, Peretti D, Jendelova P, Kwok JCF, Fawcett JW. Perineuronal nets affect memory and learning after synapse withdrawal. Translational Psychiatry. 12: 480. PMID 36379919 DOI: 10.1038/s41398-022-02226-z  0.733
2022 Fawcett JW, Fyhn M, Jendelova P, Kwok JCF, Ruzicka J, Sorg BA. The extracellular matrix and perineuronal nets in memory. Molecular Psychiatry. PMID 35760878 DOI: 10.1038/s41380-022-01634-3  0.746
2022 Fawcett JW, Kwok JCF. Proteoglycan Sulphation in the Function of the Mature Central Nervous System. Frontiers in Integrative Neuroscience. 16: 895493. PMID 35712345 DOI: 10.3389/fnint.2022.895493  0.809
2022 Barone DG, Carnicer-Lombarte A, Tourlomousis P, Hamilton RS, Prater M, Rutz AL, Dimov IB, Malliaras GG, Lacour SP, Robertson AAB, Franze K, Fawcett JW, Bryant CE. Prevention of the foreign body response to implantable medical devices by inflammasome inhibition. Proceedings of the National Academy of Sciences of the United States of America. 119: e2115857119. PMID 35298334 DOI: 10.1073/pnas.2115857119  0.424
2022 Vargova I, Kriska J, Kwok JCF, Fawcett JW, Jendelova P. Long-Term Cultures of Spinal Cord Interneurons. Frontiers in Cellular Neuroscience. 16: 827628. PMID 35197829 DOI: 10.3389/fncel.2022.827628  0.797
2022 Dubisova J, Burianova JS, Svobodova L, Makovicky P, Martinez-Varea N, Cimpean A, Fawcett JW, Kwok JCF, Kubinova S. Oral treatment of 4-methylumbelliferone reduced perineuronal nets and improved recognition memory in mice. Brain Research Bulletin. 181: 144-156. PMID 35066096 DOI: 10.1016/j.brainresbull.2022.01.011  0.75
2021 Yang S, Gigout S, Molinaro A, Naito-Matsui Y, Hilton S, Foscarin S, Nieuwenhuis B, Tan CL, Verhaagen J, Pizzorusso T, Saksida LM, Bussey TM, Kitagawa H, Kwok JCF, Fawcett JW. Chondroitin 6-sulphate is required for neuroplasticity and memory in ageing. Molecular Psychiatry. PMID 34272488 DOI: 10.1038/s41380-021-01208-9  0.765
2021 Warren PM, Fawcett JW, Kwok JCF. Substrate Specificity and Biochemical Characteristics of an Engineered Mammalian Chondroitinase ABC. Acs Omega. 6: 11223-11230. PMID 34056277 DOI: 10.1021/acsomega.0c06262  0.803
2021 Petrova V, Nieuwenhuis B, Fawcett JW, Eva R. Axonal Organelles as Molecular Platforms for Axon Growth and Regeneration after Injury. International Journal of Molecular Sciences. 22. PMID 33670312 DOI: 10.3390/ijms22041798  0.849
2021 van Erp S, van Berkel AA, Feenstra EM, Sahoo PK, Wagstaff L, Twiss JL, Fawcett JW, Eva R, Ffrench-Constant C. Age-related loss of axonal regeneration is reflected by the level of local translation. Experimental Neurology. 113594. PMID 33450233 DOI: 10.1016/j.expneurol.2020.113594  0.812
2020 Forostyak S, Forostyak O, Kwok JCF, Romanyuk N, Rehorova M, Kriska J, Dayanithi G, Raha-Chowdhury R, Jendelova P, Anderova M, Fawcett JW, Sykova E. Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats. International Journal of Molecular Sciences. 21. PMID 33339362 DOI: 10.3390/ijms21249593  0.757
2020 Krupa P, Stepankova K, Kwok JC, Fawcett JW, Cimermanova V, Jendelova P, Machova Urdzikova L. New Model of Ventral Spinal Cord Lesion Induced by Balloon Compression in Rats. Biomedicines. 8. PMID 33167447 DOI: 10.3390/biomedicines8110477  0.764
2020 Petrova V, Pearson CS, Ching J, Tribble JR, Solano AG, Yang Y, Love FM, Watt RJ, Osborne A, Reid E, Williams PA, Martin KR, Geller HM, Eva R, Fawcett JW. Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS. Nature Communications. 11: 5614. PMID 33154382 DOI: 10.1038/s41467-020-19436-y  0.858
2020 Warren PM, Andrews MR, Smith M, Bartus K, Bradbury EJ, Verhaagen J, Fawcett JW, Kwok JCF. Secretion of a mammalian chondroitinase ABC aids glial integration at PNS/CNS boundaries. Scientific Reports. 10: 11262. PMID 32647242 DOI: 10.1038/S41598-020-67526-0  0.831
2020 Nieuwenhuis B, Haenzi B, Hilton S, Carnicer-Lombarte A, Hobo B, Verhaagen J, Fawcett JW. Optimization of adeno-associated viral vector-mediated transduction of the corticospinal tract: comparison of four promoters. Gene Therapy. PMID 32576975 DOI: 10.1038/S41434-020-0169-1  0.809
2020 Nieuwenhuis B, Barber AC, Evans RS, Pearson CS, Fuchs J, MacQueen AR, van Erp S, Haenzi B, Hulshof LA, Osborne A, Conceicao R, Khatib TZ, Deshpande SS, Cave J, Ffrench-Constant C, ... ... Fawcett JW, et al. PI 3-kinase delta enhances axonal PIP to support axon regeneration in the adult CNS. Embo Molecular Medicine. e11674. PMID 32558386 DOI: 10.15252/Emmm.201911674  0.855
2020 Bradke F, Di Giovanni S, Fawcett J. Neuronal Maturation: Challenges and Opportunities in a Nascent Field. Trends in Neurosciences. 43: 360-362. PMID 32459989 DOI: 10.1016/J.Tins.2020.02.005  0.345
2020 Day P, Alves N, Daniell E, Dasgupta D, Ogborne R, Steeper A, Raza M, Ellis C, Fawcett J, Keynes R, Muir E. Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting. Plos One. 15: e0221851. PMID 31961897 DOI: 10.1371/Journal.Pone.0221851  0.55
2019 Van't Spijker HM, Rowlands D, Rossier J, Haenzi B, Fawcett JW, Kwok JCF. Neuronal Pentraxin 2 Binds PNNs and Enhances PNN Formation. Neural Plasticity. 2019: 6804575. PMID 31772567 DOI: 10.1155/2019/6804575  0.793
2019 Neumannova K, Machova-Urdzikova L, Kwok JCF, Fawcett JW, Jendelova P. Adaptation of tape removal test for measurement of sensitivity in perineal area of rat. Experimental Neurology. 113097. PMID 31707082 DOI: 10.1016/J.Expneurol.2019.113097  0.77
2019 Muir E, De Winter F, Verhaagen J, Fawcett J. Recent advances in the therapeutic uses of chondroitinase ABC. Experimental Neurology. 321: 113032. PMID 31398353 DOI: 10.1016/J.Expneurol.2019.113032  0.331
2019 Fawcett JW. The Struggle to Make CNS Axons Regenerate: Why Has It Been so Difficult? Neurochemical Research. PMID 31388931 DOI: 10.1007/S11064-019-02844-Y  0.556
2019 Kwon BK, Bloom O, Wanner IB, Curt A, Schwab JM, Fawcett J, Wang KK. Neurochemical biomarkers in spinal cord injury. Spinal Cord. PMID 31273298 DOI: 10.1038/S41393-019-0319-8  0.318
2019 Fawcett JW, Oohashi T, Pizzorusso T. The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function. Nature Reviews. Neuroscience. PMID 31263252 DOI: 10.1038/S41583-019-0196-3  0.503
2019 Rosenzweig ES, Salegio EA, Liang JJ, Weber JL, Weinholtz CA, Brock JH, Moseanko R, Hawbecker S, Pender R, Cruzen CL, Iaci JF, Caggiano AO, Blight AR, Haenzi B, Huie JR, ... ... Fawcett JW, et al. Chondroitinase improves anatomical and functional outcomes after primate spinal cord injury. Nature Neuroscience. PMID 31235933 DOI: 10.1038/S41593-019-0424-1  0.834
2019 Blight AR, Hsieh J, Curt A, Fawcett JW, Guest JD, Kleitman N, Kurpad SN, Kwon BK, Lammertse DP, Weidner N, Steeves JD. The challenge of recruitment for neurotherapeutic clinical trials in spinal cord injury. Spinal Cord. PMID 30962518 DOI: 10.1038/S41393-019-0276-2  0.306
2019 Boggio EM, Ehlert EM, Lupori L, Moloney EB, De Winter F, Vander Kooi CW, Baroncelli L, Mecollari V, Blits B, Fawcett JW, Verhaagen J, Pizzorusso T. Inhibition of Semaphorin3A Promotes Ocular Dominance Plasticity in the Adult Rat Visual Cortex. Molecular Neurobiology. PMID 30706367 DOI: 10.1007/S12035-019-1499-0  0.349
2019 Fawcett JW. Decision letter: Mature oligodendrocytes bordering lesions limit demyelination and favor myelin repair via heparan sulfate production Elife. DOI: 10.7554/Elife.51735.Sa1  0.338
2018 Fawcett JW, Verhaagen J. Intrinsic Determinants of Axon Regeneration. Developmental Neurobiology. 78: 890-897. PMID 30345655 DOI: 10.1002/Dneu.22637  0.54
2018 Rowlands D, Lensjø KK, Dinh T, Yang S, Andrews MR, Hafting T, Fyhn M, Fawcett JW, Dick G. Aggrecan Directs Extracellular Matrix-Mediated Neuronal Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 10102-10113. PMID 30282728 DOI: 10.1523/Jneurosci.1122-18.2018  0.691
2018 Fawcett JW. The Paper that Restarted Modern Central Nervous System Axon Regeneration Research. Trends in Neurosciences. 41: 239-242. PMID 29703373 DOI: 10.1016/J.Tins.2018.02.012  0.541
2018 Nieuwenhuis B, Haenzi B, Andrews MR, Verhaagen J, Fawcett JW. Integrins promote axonal regeneration after injury of the nervous system. Biological Reviews of the Cambridge Philosophical Society. PMID 29446228 DOI: 10.1111/Brv.12398  0.853
2018 Dulin JN, Adler AF, Kumamaru H, Poplawski GHD, Lee-Kubli C, Strobl H, Gibbs D, Kadoya K, Fawcett JW, Lu P, Tuszynski MH. Injured adult motor and sensory axons regenerate into appropriate organotypic domains of neural progenitor grafts. Nature Communications. 9: 84. PMID 29311559 DOI: 10.1038/S41467-017-02613-X  0.509
2018 Fawcett J. Geoffrey Raisman. 28 June 1939—27 January 2017 Biographical Memoirs of Fellows of the Royal Society. 65: 341-355. DOI: 10.1098/Rsbm.2018.0001  0.55
2017 Muir E, Raza M, Ellis C, Burnside E, Love F, Heller S, Elliot M, Daniell E, Dasgupta D, Alves N, Day P, Fawcett J, Keynes R. Trafficking and processing of bacterial proteins by mammalian cells: Insights from chondroitinase ABC. Plos One. 12: e0186759. PMID 29121057 DOI: 10.1371/Journal.Pone.0186759  0.317
2017 Kempf A, Boda E, Kwok JCF, Fritz R, Grande V, Kaelin AM, Ristic Z, Schmandke A, Schmandke A, Tews B, Fawcett JW, Pertz O, Buffo A, Schwab ME. Control of Cell Shape, Neurite Outgrowth, and Migration by a Nogo-A/HSPG Interaction. Developmental Cell. PMID 28943240 DOI: 10.1016/J.Devcel.2017.08.014  0.788
2017 Eva R, Koseki H, Kanamarlapudi V, Fawcett JW. EFA6 regulates selective polarised transport and axon regeneration from the axon initial segment. Journal of Cell Science. PMID 28935671 DOI: 10.1242/Jcs.207423  0.828
2017 Cheah M, Fawcett JW, Andrews MR. Assessment of Thermal Pain Sensation in Rats and Mice Using the Hargreaves Test. Bio-Protocol. 7. PMID 28920069 DOI: 10.21769/BioProtoc.2506  0.767
2017 Yang S, Hilton S, Alves JN, Saksida LM, Bussey T, Matthews RT, Kitagawa H, Spillantini MG, Kwok JCF, Fawcett JW. Antibody recognizing 4-sulfated chondroitin sulfate proteoglycans restores memory in tauopathy-induced neurodegeneration. Neurobiology of Aging. PMID 28890301 DOI: 10.1016/J.Neurobiolaging.2017.08.002  0.782
2017 Koseki H, Donegá M, Lam BY, Petrova V, van Erp S, Yeo GS, Kwok JC, Ffrench-Constant C, Eva R, Fawcett J. Selective Rab11 transport and the intrinsic regenerative ability of CNS axons. Elife. 6. PMID 28829741 DOI: 10.7554/Elife.26956  0.842
2017 Foscarin S, Raha-Chowdhury R, Fawcett JW, Kwok JCF. Brain ageing changes proteoglycan sulfation, rendering perineuronal nets more inhibitory. Aging. PMID 28657900 DOI: 10.18632/aging.101256  0.766
2017 Cheah M, Fawcett JW, Andrews MR. Dorsal Root Ganglion Injection and Dorsal Root Crush Injury as a Model for Sensory Axon Regeneration. Journal of Visualized Experiments : Jove. PMID 28518122 DOI: 10.3791/55535  0.854
2017 Moeendarbary E, Weber IP, Sheridan GK, Koser DE, Soleman S, Haenzi B, Bradbury EJ, Fawcett J, Franze K. The soft mechanical signature of glial scars in the central nervous system. Nature Communications. 8: 14787. PMID 28317912 DOI: 10.1038/Ncomms14787  0.828
2017 Koseki H, Donegá M, Lam BY, Petrova V, Erp Sv, Yeo GS, Kwok JC, ffrench-Constant C, Eva R, Fawcett JW. Author response: Selective rab11 transport and the intrinsic regenerative ability of CNS axons Elife. DOI: 10.7554/Elife.26956.025  0.829
2016 Fawcett JW. An integrin approach to axon regeneration. Eye (London, England). PMID 28009347 DOI: 10.1038/Eye.2016.293  0.535
2016 Sorg BA, Berretta S, Blacktop JM, Fawcett JW, Kitagawa H, Kwok JC, Miquel M. Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11459-11468. PMID 27911749 DOI: 10.1523/Jneurosci.2351-16.2016  0.769
2016 Cheah M, Fawcett JW, Haenzi B. Differential regenerative ability of sensory and motor neurons. Neuroscience Letters. PMID 27818349 DOI: 10.1016/J.Neulet.2016.11.004  0.827
2016 Andrews MR, Soleman S, Cheah M, Tumbarello DA, Mason MR, Moloney E, Verhaagen J, Bensadoun JC, Schneider B, Aebischer P, Fawcett JW. Axonal Localization of Integrins in the CNS Is Neuronal Type and Age Dependent. Eneuro. 3. PMID 27570822 DOI: 10.1523/ENEURO.0029-16.2016  0.851
2016 Dhillon RS, Parker J, Syed YA, Edgley S, Young A, Fawcett JW, Jeffery ND, Franklin RJ, Kotter MR. Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy. Acta Neuropathologica Communications. 4: 89. PMID 27552807 DOI: 10.1186/S40478-016-0359-7  0.523
2016 Heintz TG, Eva R, Fawcett JW. Regional Regulation of Purkinje Cell Dendritic Spines by Integrins and Eph/Ephrins. Plos One. 11: e0158558. PMID 27518800 DOI: 10.1371/Journal.Pone.0158558  0.757
2016 Coulson-Thomas VJ, Lauer ME, Soleman S, Zhao C, Hascall VC, Day AJ, Fawcett JW. TSG-6 is constitutively expressed in adult CNS and associated with astrocyte-mediated glial scar formation following spinal cord injury. The Journal of Biological Chemistry. PMID 27435674 DOI: 10.1074/Jbc.M115.710673  0.827
2016 Carwardine D, Wong LF, Fawcett JW, Muir EM, Granger N. Canine olfactory ensheathing cells from the olfactory mucosa can be engineered to produce active chondroitinase ABC. Journal of the Neurological Sciences. 367: 311-318. PMID 27423610 DOI: 10.1016/J.Jns.2016.06.011  0.456
2016 Cheah M, Andrews MR, Chew DJ, Moloney EB, Verhaagen J, Fässler R, Fawcett JW. Expression of an Activated Integrin Promotes Long-Distance Sensory Axon Regeneration in the Spinal Cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 7283-97. PMID 27383601 DOI: 10.1523/Jneurosci.0901-16.2016  0.848
2016 Das S, Carnicer-Lombarte A, Fawcett JW, Bora U. Bio-inspired nano tools for neuroscience. Progress in Neurobiology. PMID 27107796 DOI: 10.1016/J.Pneurobio.2016.04.008  0.359
2016 de Winter F, Kwok JC, Fawcett JW, Vo TT, Carulli D, Verhaagen J. The Chemorepulsive Protein Semaphorin 3A and Perineuronal Net-Mediated Plasticity. Neural Plasticity. 2016: 3679545. PMID 27057361 DOI: 10.1155/2016/3679545  0.819
2015 Heller JP, Kwok JC, Vecino E, Martin KR, Fawcett JW. A Method for the Isolation and Culture of Adult Rat Retinal Pigment Epithelial (RPE) Cells to Study Retinal Diseases. Frontiers in Cellular Neuroscience. 9: 449. PMID 26635529 DOI: 10.3389/Fncel.2015.00449  0.789
2015 Musick KM, Rigosa J, Narasimhan S, Wurth S, Capogrosso M, Chew DJ, Fawcett JW, Micera S, Lacour SP. Chronic multichannel neural recordings from soft regenerative microchannel electrodes during gait. Scientific Reports. 5: 14363. PMID 26400791 DOI: 10.1038/Srep14363  0.318
2015 Smith PD, Coulson-Thomas VJ, Foscarin S, Kwok JC, Fawcett JW. "GAG-ing with the neuron": The role of glycosaminoglycan patterning in the central nervous system. Experimental Neurology. PMID 26277685 DOI: 10.1016/J.Expneurol.2015.08.004  0.771
2015 Franssen EH, Zhao RR, Koseki H, Kanamarlapudi V, Hoogenraad CC, Eva R, Fawcett JW. Exclusion of integrins from CNS axons is regulated by Arf6 activation and the AIS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8359-75. PMID 26019348 DOI: 10.1523/Jneurosci.2850-14.2015  0.834
2015 Vecino E, Heller JP, Veiga-Crespo P, Martin KR, Fawcett JW. Influence of extracellular matrix components on the expression of integrins and regeneration of adult retinal ganglion cells. Plos One. 10: e0125250. PMID 26018803 DOI: 10.1371/Journal.Pone.0125250  0.707
2015 Kwon BK, Streijger F, Hill CE, Anderson AJ, Bacon M, Beattie MS, Blesch A, Bradbury EJ, Brown A, Bresnahan JC, Case CC, Colburn RW, David S, Fawcett JW, Ferguson AR, et al. Large animal and primate models of spinal cord injury for the testing of novel therapies. Experimental Neurology. 269: 154-68. PMID 25902036 DOI: 10.1016/J.Expneurol.2015.04.008  0.401
2015 Fawcett JW. The extracellular matrix in plasticity and regeneration after CNS injury and neurodegenerative disease. Progress in Brain Research. 218: 213-26. PMID 25890139 DOI: 10.1016/Bs.Pbr.2015.02.001  0.485
2015 Lorber B, Chew DJ, Hauck SM, Chong RS, Fawcett JW, Martin KR. Retinal glia promote dorsal root ganglion axon regeneration. Plos One. 10: e0115996. PMID 25816134 DOI: 10.1371/Journal.Pone.0115996  0.485
2015 Tan CL, Kwok JC, Heller JP, Zhao R, Eva R, Fawcett JW. Full length talin stimulates integrin activation and axon regeneration. Molecular and Cellular Neurosciences. 68: 1-8. PMID 25771432 DOI: 10.1016/J.Mcn.2015.03.011  0.848
2015 Wu X, Liu J, Tanadini LG, Lammertse DP, Blight AR, Kramer JL, Scivoletto G, Jones L, Kirshblum S, Abel R, Fawcett J, Field-Fote E, Guest J, Levinson B, Maier D, et al. Challenges for defining minimal clinically important difference (MCID) after spinal cord injury. Spinal Cord. 53: 84-91. PMID 25510192 DOI: 10.1038/Sc.2014.232  0.316
2015 Kwok JCF, Foscarin S, Fawcett JW. Perineuronal Nets: A Special structure in the central nervous system extracellular matrix Neuromethods. 93: 23-32. DOI: 10.1007/978-1-4939-2083-9_3  0.769
2014 Kwok JC, Yang S, Fawcett JW. Neural ECM in regeneration and rehabilitation. Progress in Brain Research. 214: 179-92. PMID 25410358 DOI: 10.1016/B978-0-444-63486-3.00008-6  0.784
2014 Heintz TG, Heller JP, Zhao R, Caceres A, Eva R, Fawcett JW. Kinesin KIF4A transports integrin β1 in developing axons of cortical neurons. Molecular and Cellular Neurosciences. 63: 60-71. PMID 25260485 DOI: 10.1016/J.Mcn.2014.09.003  0.852
2014 Tyzack GE, Sitnikov S, Barson D, Adams-Carr KL, Lau NK, Kwok JC, Zhao C, Franklin RJ, Karadottir RT, Fawcett JW, Lakatos A. Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression. Nature Communications. 5: 4294. PMID 25014177 DOI: 10.1038/Ncomms5294  0.822
2014 Kwok JC, Heller JP, Zhao RR, Fawcett JW. Targeting inhibitory chondroitin sulphate proteoglycans to promote plasticity after injury. Methods in Molecular Biology (Clifton, N.J.). 1162: 127-38. PMID 24838963 DOI: 10.1007/978-1-4939-0777-9_10  0.826
2014 Eva R, Fawcett J. Integrin signalling and traffic during axon growth and regeneration. Current Opinion in Neurobiology. 27: 179-85. PMID 24793179 DOI: 10.1016/J.Conb.2014.03.018  0.829
2014 Hyatt AJ, Wang D, van Oterendorp C, Fawcett JW, Martin KR. Mesenchymal stromal cells integrate and form longitudinally-aligned layers when delivered to injured spinal cord via a novel fibrin scaffold. Neuroscience Letters. 569: 12-7. PMID 24680849 DOI: 10.1016/J.Neulet.2014.03.023  0.368
2014 Alves JN, Muir EM, Andrews MR, Ward A, Michelmore N, Dasgupta D, Verhaagen J, Moloney EB, Keynes RJ, Fawcett JW, Rogers JH. AAV vector-mediated secretion of chondroitinase provides a sensitive tracer for axonal arborisations. Journal of Neuroscience Methods. 227: 107-20. PMID 24583077 DOI: 10.1016/J.Jneumeth.2014.02.010  0.815
2014 Moshayedi P, Ng G, Kwok JC, Yeo GS, Bryant CE, Fawcett JW, Franze K, Guck J. The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system. Biomaterials. 35: 3919-25. PMID 24529901 DOI: 10.1016/J.Biomaterials.2014.01.038  0.766
2014 Kappagantula S, Andrews MR, Cheah M, Abad-Rodriguez J, Dotti CG, Fawcett JW. Neu3 sialidase-mediated ganglioside conversion is necessary for axon regeneration and is blocked in CNS axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2477-92. PMID 24523539 DOI: 10.1523/Jneurosci.4432-13.2014  0.837
2013 Chew DJ, Zhu L, Delivopoulos E, Minev IR, Musick KM, Mosse CA, Craggs M, Donaldson N, Lacour SP, McMahon SB, Fawcett JW. A microchannel neuroprosthesis for bladder control after spinal cord injury in rat. Science Translational Medicine. 5: 210ra155. PMID 24197736 DOI: 10.1126/Scitranslmed.3007186  0.353
2013 Soleman S, Filippov MA, Dityatev A, Fawcett JW. Targeting the neural extracellular matrix in neurological disorders. Neuroscience. 253: 194-213. PMID 24012743 DOI: 10.1016/J.Neuroscience.2013.08.050  0.813
2013 Dick G, Tan CL, Alves JN, Ehlert EM, Miller GM, Hsieh-Wilson LC, Sugahara K, Oosterhof A, van Kuppevelt TH, Verhaagen J, Fawcett JW, Kwok JC. Semaphorin 3A binds to the perineuronal nets via chondroitin sulfate type E motifs in rodent brains. The Journal of Biological Chemistry. 288: 27384-95. PMID 23940048 DOI: 10.1074/Jbc.M111.310029  0.806
2013 Gumy LF, Chew DJ, Tortosa E, Katrukha EA, Kapitein LC, Tolkovsky AM, Hoogenraad CC, Fawcett JW. The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11329-45. PMID 23843507 DOI: 10.1523/Jneurosci.5221-12.2013  0.834
2013 Zhao RR, Fawcett JW. Combination treatment with chondroitinase ABC in spinal cord injury--breaking the barrier. Neuroscience Bulletin. 29: 477-83. PMID 23839053 DOI: 10.1007/S12264-013-1359-2  0.432
2013 Zhao RR, Andrews MR, Wang D, Warren P, Gullo M, Schnell L, Schwab ME, Fawcett JW. Combination treatment with anti-Nogo-A and chondroitinase ABC is more effective than single treatments at enhancing functional recovery after spinal cord injury. The European Journal of Neuroscience. 38: 2946-61. PMID 23790207 DOI: 10.1111/Ejn.12276  0.83
2013 Vo T, Carulli D, Ehlert EM, Kwok JC, Dick G, Mecollari V, Moloney EB, Neufeld G, de Winter F, Fawcett JW, Verhaagen J. The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain. Molecular and Cellular Neurosciences. 56: 186-200. PMID 23665579 DOI: 10.1016/J.Mcn.2013.04.009  0.832
2013 Romberg C, Yang S, Melani R, Andrews MR, Horner AE, Spillantini MG, Bussey TJ, Fawcett JW, Pizzorusso T, Saksida LM. Depletion of perineuronal nets enhances recognition memory and long-term depression in the perirhinal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7057-65. PMID 23595763 DOI: 10.1523/Jneurosci.6267-11.2013  0.673
2013 Vorobyov V, Kwok JC, Fawcett JW, Sengpiel F. Effects of digesting chondroitin sulfate proteoglycans on plasticity in cat primary visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 234-43. PMID 23283337 DOI: 10.1523/Jneurosci.2283-12.2013  0.764
2013 Dassie E, Andrews MR, Bensadoun JC, Cacquevel M, Schneider BL, Aebischer P, Wouters FS, Richardson JC, Hussain I, Howlett DR, Spillantini MG, Fawcett JW. Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model. Neurobiology of Aging. 34: 1355-68. PMID 23273572 DOI: 10.1016/J.Neurobiolaging.2012.11.011  0.664
2013 Granger N, Chew D, Fairhurst P, Fawcett JW, Lacour SP, Craggs M, Mosse CA, Donaldson N, Jeffery ND. Use of an Implanted Sacral Nerve Stimulator to Restore Urine Voiding in Chronically Paraplegic Dogs Journal of Veterinary Internal Medicine. 27: 99-105. PMID 23194073 DOI: 10.1111/Jvim.12011  0.317
2012 Orlando C, Ster J, Gerber U, Fawcett JW, Raineteau O. Perisynaptic chondroitin sulfate proteoglycans restrict structural plasticity in an integrin-dependent manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 18009-17, 18017a. PMID 23238717 DOI: 10.1523/Jneurosci.2406-12.2012  0.371
2012 Eva R, Andrews MR, Franssen EH, Fawcett JW. Intrinsic mechanisms regulating axon regeneration: an integrin perspective. International Review of Neurobiology. 106: 75-104. PMID 23211460 DOI: 10.1016/B978-0-12-407178-0.00004-1  0.856
2012 Chew DJ, Fawcett JW, Andrews MR. The challenges of long-distance axon regeneration in the injured CNS. Progress in Brain Research. 201: 253-94. PMID 23186719 DOI: 10.1016/B978-0-444-59544-7.00013-5  0.786
2012 Fawcett JW, Schwab ME, Montani L, Brazda N, Müller HW. Defeating inhibition of regeneration by scar and myelin components. Handbook of Clinical Neurology. 109: 503-22. PMID 23098733 DOI: 10.1016/B978-0-444-52137-8.00031-0  0.521
2012 Bosch KD, Bradbury EJ, Verhaagen J, Fawcett JW, McMahon SB. Chondroitinase ABC promotes plasticity of spinal reflexes following peripheral nerve injury. Experimental Neurology. 238: 64-78. PMID 22917776 DOI: 10.1016/J.Expneurol.2012.08.003  0.364
2012 Eva R, Crisp S, Marland JR, Norman JC, Kanamarlapudi V, ffrench-Constant C, Fawcett JW. ARF6 directs axon transport and traffic of integrins and regulates axon growth in adult DRG neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 10352-64. PMID 22836268 DOI: 10.1523/Jneurosci.1409-12.2012  0.823
2012 Tan CL, Andrews MR, Kwok JC, Heintz TG, Gumy LF, Fässler R, Fawcett JW. Kindlin-1 enhances axon growth on inhibitory chondroitin sulfate proteoglycans and promotes sensory axon regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7325-35. PMID 22623678 DOI: 10.1523/Jneurosci.5472-11.2012  0.863
2012 Bradke F, Fawcett JW, Spira ME. Assembly of a new growth cone after axotomy: The precursor to axon regeneration Nature Reviews Neuroscience. 13: 183-193. PMID 22334213 DOI: 10.1038/Nrn3176  0.504
2012 Kwok JC, Yuen YL, Lau WK, Zhang FX, Fawcett JW, Chan YS, Shum DK. Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons. Neural Development. 7: 6. PMID 22305371 DOI: 10.1186/1749-8104-7-6  0.807
2012 Kwok JCF, Warren P, Fawcett JW. Chondroitin sulfate: A key molecule in the brain matrix International Journal of Biochemistry and Cell Biology. 44: 582-586. PMID 22265655 DOI: 10.1016/J.Biocel.2012.01.004  0.809
2012 FitzGerald JJ, Lago N, Benmerah S, Serra J, Watling CP, Cameron RE, Tarte E, Lacour SP, McMahon SB, Fawcett JW. A regenerative microchannel neural interface for recording from and stimulating peripheral axons in vivo. Journal of Neural Engineering. 9: 016010. PMID 22258138 DOI: 10.1088/1741-2560/9/1/016010  0.643
2012 Afshari FT, Fawcett JW. An in vitro assay to examine oligodendrocyte precursor cell migration on astrocytes. Methods in Molecular Biology (Clifton, N.J.). 814: 393-9. PMID 22144321 DOI: 10.1007/978-1-61779-452-0_26  0.466
2012 Afshari FT, Fawcett JW. Astrocyte-Schwann-cell coculture systems. Methods in Molecular Biology (Clifton, N.J.). 814: 381-91. PMID 22144320 DOI: 10.1007/978-1-61779-452-0_25  0.463
2012 García-Alías G, Fawcett JW. Training and anti-CSPG combination therapy for spinal cord injury. Experimental Neurology. 235: 26-32. PMID 21946272 DOI: 10.1016/J.Expneurol.2011.09.009  0.402
2012 Lorber B, Guidi A, Fawcett JW, Martin KR. Activated retinal glia mediated axon regeneration in experimental glaucoma. Neurobiology of Disease. 45: 243-52. PMID 21867754 DOI: 10.1016/J.Nbd.2011.08.008  0.436
2012 Wang D, Fawcett J. The perineuronal net and the control of cns plasticity Cell and Tissue Research. 349: 147-160. DOI: 10.1007/S00441-012-1375-Y  0.394
2011 García-Alías G, Petrosyan HA, Schnell L, Horner PJ, Bowers WJ, Mendell LM, Fawcett JW, Arvanian VL. Chondroitinase ABC combined with neurotrophin NT-3 secretion and NR2D expression promotes axonal plasticity and functional recovery in rats with lateral hemisection of the spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17788-99. PMID 22159095 DOI: 10.1523/Jneurosci.4308-11.2011  0.805
2011 Fawcett JW, Kalluri R, Duffield JS, Silver J. Starting the scar: A primary role for pericytes? Nature Medicine. 17. PMID 21900921 DOI: 10.1038/Nm0911-1052  0.361
2011 Kwok JC, Dick G, Wang D, Fawcett JW. Extracellular matrix and perineuronal nets in CNS repair. Developmental Neurobiology. 71: 1073-89. PMID 21898855 DOI: 10.1002/Dneu.20974  0.809
2011 Zhao RR, Muir EM, Alves JN, Rickman H, Allan AY, Kwok JC, Roet KC, Verhaagen J, Schneider BL, Bensadoun JC, Ahmed SG, Yáñez-Muñoz RJ, Keynes RJ, Fawcett JW, Rogers JH. Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons. Journal of Neuroscience Methods. 201: 228-38. PMID 21855577 DOI: 10.1016/J.Jneumeth.2011.08.003  0.85
2011 Al-Mayhani MT, Grenfell R, Narita M, Piccirillo S, Kenney-Herbert E, Fawcett JW, Collins VP, Ichimura K, Watts C. NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature. Neuro-Oncology. 13: 830-45. PMID 21798846 DOI: 10.1093/Neuonc/Nor088  0.306
2011 Lin R, Rosahl TW, Whiting PJ, Fawcett JW, Kwok JC. 6-Sulphated chondroitins have a positive influence on axonal regeneration. Plos One. 6: e21499. PMID 21747937 DOI: 10.1371/Journal.Pone.0021499  0.856
2011 Wang D, Ichiyama RM, Zhao R, Andrews MR, Fawcett JW. Chondroitinase combined with rehabilitation promotes recovery of forelimb function in rats with chronic spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 9332-44. PMID 21697383 DOI: 10.1523/Jneurosci.0983-11.2011  0.696
2011 Tan CL, Kwok JC, Patani R, Ffrench-Constant C, Chandran S, Fawcett JW. Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6289-95. PMID 21525268 DOI: 10.1523/Jneurosci.0008-11.2011  0.839
2011 Afshari FT, Kwok JC, Fawcett JW. Analysis of Schwann-astrocyte interactions using in vitro assays. Journal of Visualized Experiments : Jove. PMID 21304451 DOI: 10.3791/2214  0.815
2011 Gumy LF, Yeo GS, Tung YC, Zivraj KH, Willis D, Coppola G, Lam BY, Twiss JL, Holt CE, Fawcett JW. Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization. Rna (New York, N.Y.). 17: 85-98. PMID 21098654 DOI: 10.1261/Rna.2386111  0.827
2011 Zariffa J, Kramer JL, Fawcett JW, Lammertse DP, Blight AR, Guest J, Jones L, Burns S, Schubert M, Bolliger M, Curt A, Steeves JD. Characterization of neurological recovery following traumatic sensorimotor complete thoracic spinal cord injury. Spinal Cord. 49: 463-71. PMID 20938451 DOI: 10.1038/Sc.2010.140  0.338
2011 Kwok JCF, Tan CL, Wang D, Heller J, Fawcett JW. Chondroitin sulfates in axon regeneration and plasticity Trends in Glycoscience and Glycotechnology. 23: 201-211. DOI: 10.4052/Tigg.23.201  0.846
2011 Tarte EJ, Fitzgerald JJ, Lago N, Benmerah S, Serra J, Watling CP, Cameron RE, Lacour SP, McMahon SB, Fawcett JW. The spiral peripheral nerve interface: Design, fabrication and performance Ifmbe Proceedings. 37: 1338-1341. DOI: 10.1007/978-3-642-23508-5_345  0.46
2010 Moshayedi P, Da F Costa L, Christ A, Lacour SP, Fawcett J, Guck J, Franze K. Mechanosensitivity of astrocytes on optimized polyacrylamide gels analyzed by quantitative morphometry Journal of Physics Condensed Matter. 22. PMID 21386440 DOI: 10.1088/0953-8984/22/19/194114  0.304
2010 Zivraj KH, Tung YC, Piper M, Gumy L, Fawcett JW, Yeo GS, Holt CE. Subcellular profiling reveals distinct and developmentally regulated repertoire of growth cone mRNAs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15464-78. PMID 21084603 DOI: 10.1523/Jneurosci.1800-10.2010  0.795
2010 Eva R, Dassie E, Caswell PT, Dick G, ffrench-Constant C, Norman JC, Fawcett JW. Rab11 and its effector Rab coupling protein contribute to the trafficking of beta 1 integrins during axon growth in adult dorsal root ganglion neurons and PC12 cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11654-69. PMID 20810886 DOI: 10.1523/Jneurosci.2425-10.2010  0.797
2010 Hyatt AJ, Wang D, Kwok JC, Fawcett JW, Martin KR. Controlled release of chondroitinase ABC from fibrin gel reduces the level of inhibitory glycosaminoglycan chains in lesioned spinal cord. Journal of Controlled Release : Official Journal of the Controlled Release Society. 147: 24-9. PMID 20620180 DOI: 10.1016/J.Jconrel.2010.06.026  0.787
2010 Kwok JC, Carulli D, Fawcett JW. In vitro modeling of perineuronal nets: hyaluronan synthase and link protein are necessary for their formation and integrity. Journal of Neurochemistry. 114: 1447-59. PMID 20584105 DOI: 10.1111/J.1471-4159.2010.06878.X  0.802
2010 Carulli D, Pizzorusso T, Kwok JC, Putignano E, Poli A, Forostyak S, Andrews MR, Deepa SS, Glant TT, Fawcett JW. Animals lacking link protein have attenuated perineuronal nets and persistent plasticity. Brain : a Journal of Neurology. 133: 2331-47. PMID 20566484 DOI: 10.1093/Brain/Awq145  0.807
2010 Lacour SP, Benmerah S, Tarte E, FitzGerald J, Serra J, McMahon S, Fawcett J, Graudejus O, Yu Z, Morrison B. Flexible and stretchable micro-electrodes for in vitro and in vivo neural interfaces. Medical & Biological Engineering & Computing. 48: 945-54. PMID 20535574 DOI: 10.1007/S11517-010-0644-8  0.526
2010 Hunanyan AS, García-Alías G, Alessi V, Levine JM, Fawcett JW, Mendell LM, Arvanian VL. Role of chondroitin sulfate proteoglycans in axonal conduction in Mammalian spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 7761-9. PMID 20534825 DOI: 10.1523/Jneurosci.4659-09.2010  0.811
2010 Dobbertin A, Czvitkovich S, Theocharidis U, Garwood J, Andrews MR, Properzi F, Lin R, Fawcett JW, Faissner A. Analysis of combinatorial variability reveals selective accumulation of the fibronectin type III domains B and D of tenascin-C in injured brain. Experimental Neurology. 225: 60-73. PMID 20451518 DOI: 10.1016/J.Expneurol.2010.04.019  0.82
2010 Afshari FT, Kwok JC, Fawcett JW. Astrocyte-produced ephrins inhibit schwann cell migration via VAV2 signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4246-55. PMID 20335460 DOI: 10.1523/Jneurosci.3351-09.2010  0.811
2010 Afshari FT, Kwok JC, Andrews MR, Blits B, Martin KR, Faissner A, Ffrench-Constant C, Fawcett JW. Integrin activation or alpha 9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration. Brain : a Journal of Neurology. 133: 448-64. PMID 20159768 DOI: 10.1093/Brain/Awp319  0.78
2010 Afshari FT, Kwok JC, White L, Fawcett JW. Schwann cell migration is integrin-dependent and inhibited by astrocyte-produced aggrecan. Glia. 58: 857-69. PMID 20155822 DOI: 10.1002/Glia.20970  0.832
2010 Muir EM, Fyfe I, Gardiner S, Li L, Warren P, Fawcett JW, Keynes RJ, Rogers JH. Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells. Journal of Biotechnology. 145: 103-10. PMID 19900493 DOI: 10.1016/J.Jbiotec.2009.11.002  0.801
2010 Gumy LF, Tan CL, Fawcett JW. The role of local protein synthesis and degradation in axon regeneration. Experimental Neurology. 223: 28-37. PMID 19520073 DOI: 10.1016/J.Expneurol.2009.06.004  0.828
2010 Fawcett JW. Spinal cord regeneration and functional recovery: Strategies Encyclopedia of Neuroscience. 303-308. DOI: 10.1016/B978-008045046-9.00008-5  0.462
2010 Fawcett JW. Spinal cord regeneration after injury: Bridging by schwann cells and bioimplants Encyclopedia of Neuroscience. 299-302. DOI: 10.1016/B978-008045046-9.00004-8  0.441
2009 Afshari FT, Kappagantula S, Fawcett JW. Extrinsic and intrinsic factors controlling axonal regeneration after spinal cord injury. Expert Reviews in Molecular Medicine. 11: e37. PMID 19968910 DOI: 10.1017/S1462399409001288  0.836
2009 Lacour SP, Fitzgerald JJ, Lago N, Tarte E, McMahon S, Fawcett J. Long micro-channel electrode arrays: a novel type of regenerative peripheral nerve interface. Ieee Transactions On Neural Systems and Rehabilitation Engineering : a Publication of the Ieee Engineering in Medicine and Biology Society. 17: 454-60. PMID 19744916 DOI: 10.1109/Tnsre.2009.2031241  0.573
2009 García-Alías G, Barkhuysen S, Buckle M, Fawcett JW. Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation. Nature Neuroscience. 12: 1145-51. PMID 19668200 DOI: 10.1038/Nn.2377  0.371
2009 Fawcett J. Molecular control of brain plasticity and repair Progress in Brain Research. 175: 501-509. PMID 19660677 DOI: 10.1016/S0079-6123(09)17534-9  0.457
2009 Fawcett JW, Curt A. Damage control in the nervous system: rehabilitation in a plastic environment. Nature Medicine. 15: 735-6. PMID 19584862 DOI: 10.1038/Nm0709-735  0.31
2009 Vogelaar CF, Gervasi NM, Gumy LF, Story DJ, Raha-Chowdhury R, Leung KM, Holt CE, Fawcett JW. Axonal mRNAs: characterisation and role in the growth and regeneration of dorsal root ganglion axons and growth cones. Molecular and Cellular Neurosciences. 42: 102-15. PMID 19520167 DOI: 10.1016/J.Mcn.2009.06.002  0.818
2009 Zhao JW, Raha-Chowdhury R, Fawcett JW, Watts C. Astrocytes and oligodendrocytes can be generated from NG2+ progenitors after acute brain injury: intracellular localization of oligodendrocyte transcription factor 2 is associated with their fate choice. The European Journal of Neuroscience. 29: 1853-69. PMID 19473238 DOI: 10.1111/J.1460-9568.2009.06736.X  0.403
2009 Fawcett JW. Recovery from spinal cord injury: regeneration, plasticity and rehabilitation. Brain : a Journal of Neurology. 132: 1417-8. PMID 19429905 DOI: 10.1093/Brain/Awp121  0.473
2009 Blight A, Curt A, Ditunno JF, Dobkin B, Ellaway P, Fawcett J, Fehlings M, Grossman RG, Lammertse DP, Privat A, Steeves J, Tuszynski M, Kalichman M, Guest JD. Position statement on the sale of unproven cellular therapies for spinal cord injury: the international campaign for cures of spinal cord injury paralysis. Spinal Cord. 47: 713-4. PMID 19417762 DOI: 10.1038/Sc.2008.179  0.345
2009 Andrews MR, Czvitkovich S, Dassie E, Vogelaar CF, Faissner A, Blits B, Gage FH, ffrench-Constant C, Fawcett JW. Alpha9 integrin promotes neurite outgrowth on tenascin-C and enhances sensory axon regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5546-57. PMID 19403822 DOI: 10.1523/Jneurosci.0759-09.2009  0.778
2009 Arvanian VL, Schnell L, Lou L, Golshani R, Hunanyan A, Ghosh A, Pearse DD, Robinson JK, Schwab ME, Fawcett JW, Mendell LM. Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fibers to motoneurons. Experimental Neurology. 216: 471-80. PMID 19320005 DOI: 10.1016/J.Expneurol.2009.01.004  0.395
2009 FitzGerald JJ, Lacour SP, McMahon SB, Fawcett JW. Microchannel electrodes for recording and stimulation: in vitro evaluation. Ieee Transactions On Bio-Medical Engineering. 56: 1524-34. PMID 19203882 DOI: 10.1109/Tbme.2009.2013960  0.561
2009 Hunanyan AS, Garcia-Alias G, Levine JM, Fawcett JW, Mendell LM, Arvanian VL. Role of chondroitin sulfate proteoglycans (CSPGs) in synaptic plasticity and neurotransmission in mammalian spinal cord. Nature Precedings. DOI: 10.1038/Npre.2009.3681.1  0.816
2009 Franze K, Svoboda H, Moshayedi P, Christ A, Fawcett J, Kas JA, Holt CE, Guck J. Mechanics in neuronal development Biophysical Journal. 96: 196a. DOI: 10.1016/J.Bpj.2008.12.1053  0.501
2008 FitzGerald JJ, Lacour SP, Fawcett JW. Recording with microchannel electrodes in a noisy environment. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2008: 34-7. PMID 19162587 DOI: 10.1109/IEMBS.2008.4649084  0.508
2008 Fawcett JW. Bridging spinal cord injuries. Journal of Biology. 7: 25. PMID 18947368 DOI: 10.1186/Jbiol89  0.476
2008 Gervasi NM, Kwok JC, Fawcett JW. Role of extracellular factors in axon regeneration in the CNS: implications for therapy. Regenerative Medicine. 3: 907-23. PMID 18947312 DOI: 10.2217/17460751.3.6.907  0.837
2008 Kwok JC, Afshari F, García-Alías G, Fawcett JW. Proteoglycans in the central nervous system: plasticity, regeneration and their stimulation with chondroitinase ABC. Restorative Neurology and Neuroscience. 26: 131-45. PMID 18820407  0.838
2008 Hampton DW, Anderson J, Pryce G, Irvine KA, Giovannoni G, Fawcett JW, Compston A, Franklin RJ, Baker D, Chandran S. An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss. Journal of Neuroimmunology. 201: 200-11. PMID 18672298 DOI: 10.1016/J.Jneuroim.2008.05.034  0.702
2008 Verma P, Garcia-Alias G, Fawcett JW. Spinal cord repair: bridging the divide. Neurorehabilitation and Neural Repair. 22: 429-37. PMID 18487422 DOI: 10.1177/1545968307313500  0.763
2008 Galtrey CM, Kwok JC, Carulli D, Rhodes KE, Fawcett JW. Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord. The European Journal of Neuroscience. 27: 1373-90. PMID 18364019 DOI: 10.1111/J.1460-9568.2008.06108.X  0.807
2008 Fitzgerald JJ, Lacour SP, McMahon SB, Fawcett JW. Microchannels as axonal amplifiers. Ieee Transactions On Bio-Medical Engineering. 55: 1136-46. PMID 18334406 DOI: 10.1109/Tbme.2007.909533  0.642
2008 Properzi F, Lin R, Kwok J, Naidu M, van Kuppevelt TH, Ten Dam GB, Camargo LM, Raha-Chowdhury R, Furukawa Y, Mikami T, Sugahara K, Fawcett JW. Heparan sulphate proteoglycans in glia and in the normal and injured CNS: expression of sulphotransferases and changes in sulphation. The European Journal of Neuroscience. 27: 593-604. PMID 18279312 DOI: 10.1111/J.1460-9568.2008.06042.X  0.812
2008 Singhal S, Lawrence JM, Bhatia B, Ellis JS, Kwan AS, Macneil A, Luthert PJ, Fawcett JW, Perez MT, Khaw PT, Limb GA. Chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted Müller stem cells into degenerating retina. Stem Cells (Dayton, Ohio). 26: 1074-82. PMID 18218817 DOI: 10.1634/Stemcells.2007-0898  0.33
2008 García-Alías G, Lin R, Akrimi SF, Story D, Bradbury EJ, Fawcett JW. Therapeutic time window for the application of chondroitinase ABC after spinal cord injury. Experimental Neurology. 210: 331-8. PMID 18158149 DOI: 10.1016/J.Expneurol.2007.11.002  0.795
2008 Lin R, Kwok JC, Crespo D, Fawcett JW. Chondroitinase ABC has a long-lasting effect on chondroitin sulphate glycosaminoglycan content in the injured rat brain. Journal of Neurochemistry. 104: 400-8. PMID 18005340 DOI: 10.1111/J.1471-4159.2007.05066.X  0.833
2008 Arvanian VL, Schnell L, Lou L, Golshani R, Hunanyan A, Ghosh A, Pearse DD, Robinson JK, Schwab ME, Fawcett JW, Mendell LM. Chronic thoracic hemisection spinal cord injury in adult rats induces a progressive decline in transmission from uninjured fibers to lumbar motoneurons Nature Precedings. DOI: 10.1038/Npre.2008.2165.1  0.369
2008 Lacour SP, Atta R, FitzGerald JJ, Blamire M, Tarte E, Fawcett J. Polyimide micro-channel arrays for peripheral nerve regenerative implants Sensors and Actuators, a: Physical. 147: 456-463. DOI: 10.1016/J.Sna.2008.05.031  0.558
2008 Fawcett JW. Modifying the extracellular matrix as a treatment to improve functional recovery after spinal cord injury Cns Regeneration. 337-353. DOI: 10.1016/B978-012373994-0.50016-6  0.377
2008 Vogelaar CF, Fawcett JW. Axonal mRNA in Regeneration Neural Degeneration and Repair: Gene Expression Profiling, Proteomics and Systems Biology. 135-151. DOI: 10.1002/9783527622467.ch6  0.367
2007 Laabs TL, Wang H, Katagiri Y, McCann T, Fawcett JW, Geller HM. Inhibiting glycosaminoglycan chain polymerization decreases the inhibitory activity of astrocyte-derived chondroitin sulfate proteoglycans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14494-501. PMID 18160657 DOI: 10.1523/Jneurosci.2807-07.2007  0.51
2007 Hampton DW, Asher RA, Kondo T, Steeves JD, Ramer MS, Fawcett JW. A potential role for bone morphogenetic protein signalling in glial cell fate determination following adult central nervous system injury in vivo. The European Journal of Neuroscience. 26: 3024-35. PMID 18028109 DOI: 10.1111/J.1460-9568.2007.05940.X  0.794
2007 FitzGerald J, Fawcett J. Repair in the central nervous system Journal of Bone and Joint Surgery-British Volume. 89: 1413-1420. PMID 17998174 DOI: 10.1302/0301-620X.89B11.19651  0.643
2007 Crespo D, Asher RA, Lin R, Rhodes KE, Fawcett JW. How does chondroitinase promote functional recovery in the damaged CNS? Experimental Neurology. 206: 159-71. PMID 17572406 DOI: 10.1016/J.Expneurol.2007.05.001  0.816
2007 Courtine G, Bunge MB, Fawcett JW, Grossman RG, Kaas JH, Lemon R, Maier I, Martin J, Nudo RJ, Ramon-Cueto A, Rouiller EM, Schnell L, Wannier T, Schwab ME, Edgerton VR. Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans? Nature Medicine. 13: 561-6. PMID 17479102 DOI: 10.1038/Nm1595  0.58
2007 Galtrey CM, Fawcett JW. Characterization of tests of functional recovery after median and ulnar nerve injury and repair in the rat forelimb. Journal of the Peripheral Nervous System : Jpns. 12: 11-27. PMID 17374098 DOI: 10.1111/J.1529-8027.2007.00113.X  0.775
2007 Smith JM, Lunga P, Story D, Harris N, Le Belle J, James MF, Pickard JD, Fawcett JW. Inosine promotes recovery of skilled motor function in a model of focal brain injury. Brain : a Journal of Neurology. 130: 915-25. PMID 17293357 DOI: 10.1093/Brain/Awl393  0.457
2007 Hampton DW, Steeves JD, Fawcett JW, Ramer MS. Spinally upregulated noggin suppresses axonal and dendritic plasticity following dorsal rhizotomy. Experimental Neurology. 204: 366-79. PMID 17258709 DOI: 10.1016/J.Expneurol.2006.11.017  0.731
2007 Galtrey CM, Asher RA, Nothias F, Fawcett JW. Promoting plasticity in the spinal cord with chondroitinase improves functional recovery after peripheral nerve repair. Brain : a Journal of Neurology. 130: 926-39. PMID 17255150 DOI: 10.1093/Brain/Awl372  0.814
2007 Galtrey CM, Fawcett JW. The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system. Brain Research Reviews. 54: 1-18. PMID 17222456 DOI: 10.1016/J.Brainresrev.2006.09.006  0.786
2007 Carulli D, Rhodes KE, Fawcett JW. Upregulation of aggrecan, link protein 1, and hyaluronan synthases during formation of perineuronal nets in the rat cerebellum. The Journal of Comparative Neurology. 501: 83-94. PMID 17206619 DOI: 10.1002/Cne.21231  0.807
2007 Fawcett JW, Curt A, Steeves JD, Coleman WP, Tuszynski MH, Lammertse D, Bartlett PF, Blight AR, Dietz V, Ditunno J, Dobkin BH, Havton LA, Ellaway PH, Fehlings MG, Privat A, et al. Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials. Spinal Cord. 45: 190-205. PMID 17179973 DOI: 10.1038/Sj.Sc.3102007  0.323
2006 Fawcett JW. Novel strategies for protection and repair of the central nervous system. Clinical Medicine (London, England). 6: 598-603. PMID 17228561 DOI: 10.7861/Clinmedicine.6-6-598  0.364
2006 Fawcett JW. The glial response to injury and its role in the inhibition of CNS repair. Advances in Experimental Medicine and Biology. 557: 11-24. PMID 16955702 DOI: 10.1007/0-387-30128-3_2  0.531
2006 Deepa SS, Carulli D, Galtrey C, Rhodes K, Fukuda J, Mikami T, Sugahara K, Fawcett JW. Composition of perineuronal net extracellular matrix in rat brain: a different disaccharide composition for the net-associated proteoglycans. The Journal of Biological Chemistry. 281: 17789-800. PMID 16644727 DOI: 10.1074/Jbc.M600544200  0.773
2006 Rhodes KE, Raivich G, Fawcett JW. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience. 140: 87-100. PMID 16631314 DOI: 10.1016/J.Neuroscience.2006.01.055  0.451
2006 Fawcett JW. Overcoming inhibition in the damaged spinal cord Journal of Neurotrauma. 23: 371-383. PMID 16629623 DOI: 10.1089/Neu.2006.23.371  0.509
2006 Gaughwin PM, Caldwell MA, Anderson JM, Schwiening CJ, Fawcett JW, Compston DA, Chandran S. Astrocytes promote neurogenesis from oligodendrocyte precursor cells. The European Journal of Neuroscience. 23: 945-56. PMID 16519659 DOI: 10.1111/J.1460-9568.2006.04625.X  0.399
2006 Carulli D, Rhodes KE, Brown DJ, Bonnert TP, Pollack SJ, Oliver K, Strata P, Fawcett JW. Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components. The Journal of Comparative Neurology. 494: 559-77. PMID 16374793 DOI: 10.1002/Cne.20822  0.806
2006 Cook G, Fawcett J, Keynes R, Tessier-Lavigne M. Introduction. The regenerating brain Philosophical Transactions of the Royal Society B: Biological Sciences. 361: 1459-1461. DOI: 10.1098/Rstb.2006.1893  0.357
2005 Strappe PM, Hampton DW, Brown D, Cachon-Gonzalez B, Caldwell M, Fawcett JW, Lever AM. Identification of unique reciprocal and non reciprocal cross packaging relationships between HIV-1, HIV-2 and SIV reveals an efficient SIV/HIV-2 lentiviral vector system with highly favourable features for in vivo testing and clinical usage. Retrovirology. 2: 55. PMID 16168051 DOI: 10.1186/1742-4690-2-55  0.617
2005 Strappe PM, Hampton DW, Cachon-Gonzalez B, Fawcett JW, Lever A. Delivery of a lentiviral vector in a Pluronic F127 gel to cells of the central nervous system. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 61: 126-33. PMID 16154331 DOI: 10.1016/J.Ejpb.2005.06.006  0.669
2005 Verma P, Fawcett J. Spinal cord regeneration. Advances in Biochemical Engineering/Biotechnology. 94: 43-66. PMID 15915868 DOI: 10.1007/B99999  0.395
2005 Chierzi S, Ratto GM, Verma P, Fawcett JW. The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK. The European Journal of Neuroscience. 21: 2051-62. PMID 15869501 DOI: 10.1111/J.1460-9568.2005.04066.X  0.526
2005 Asher RA, Morgenstern DA, Properzi F, Nishiyama A, Levine JM, Fawcett JW. Two separate metalloproteinase activities are responsible for the shedding and processing of the NG2 proteoglycan in vitro. Molecular and Cellular Neurosciences. 29: 82-96. PMID 15866049 DOI: 10.1016/J.Mcn.2005.02.001  0.794
2005 Anderson DK, Beattie M, Blesch A, Bresnahan J, Bunge M, Dietrich D, Dietz V, Dobkin B, Fawcett J, Fehlings M, Fischer I, Grossman R, Guest J, Hagg T, Hall ED, et al. Recommended guidelines for studies of human subjects with spinal cord injury. Spinal Cord. 43: 453-8. PMID 15824756 DOI: 10.1038/Sj.Sc.3101746  0.574
2005 Carulli D, Laabs T, Geller HM, Fawcett JW. Chondroitin sulfate proteoglycans in neural development and regeneration. Current Opinion in Neurobiology. 15: 116-20. PMID 15721753 DOI: 10.1016/J.Conb.2005.01.014  0.794
2005 Properzi F, Carulli D, Asher RA, Muir E, Camargo LM, van Kuppevelt TH, ten Dam GB, Furukawa Y, Mikami T, Sugahara K, Toida T, Geller HM, Fawcett JW. Chondroitin 6-sulphate synthesis is up-regulated in injured CNS, induced by injury-related cytokines and enhanced in axon-growth inhibitory glia. The European Journal of Neuroscience. 21: 378-90. PMID 15673437 DOI: 10.1111/J.1460-9568.2005.03876.X  0.844
2005 Verma P, Chierzi S, Codd AM, Campbell DS, Meyer RL, Holt CE, Fawcett JW. Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 331-42. PMID 15647476 DOI: 10.1523/Jneurosci.3073-04.2005  0.518
2004 Adcock KH, Brown DJ, Shearer MC, Shewan D, Schachner M, Smith GM, Geller HM, Fawcett JW. Axon behaviour at Schwann cell - astrocyte boundaries: manipulation of axon signalling pathways and the neural adhesion molecule L1 can enable axons to cross. The European Journal of Neuroscience. 20: 1425-35. PMID 15355310 DOI: 10.1111/J.1460-9568.2004.03573.X  0.845
2004 Hampton DW, Seitz A, Chen P, Heber-Katz E, Fawcett JW. Altered CNS response to injury in the MRL/MpJ mouse Neuroscience. 127: 821-832. PMID 15312895 DOI: 10.1016/J.Neuroscience.2004.05.057  0.733
2004 Hampton DW, Rhodes KE, Zhao C, Franklin RJM, Fawcett JW. The responses of oligodendrocyte precursor cells, astrocytes and microglia to a cortical stab injury, in the brain Neuroscience. 127: 813-820. PMID 15312894 DOI: 10.1016/J.Neuroscience.2004.05.028  0.703
2004 Gubba EM, Fawcett JW, Herbert J. The effects of corticosterone and dehydroepiandrosterone on neurotrophic factor mRNA expression in primary hippocampal and astrocyte cultures Molecular Brain Research. 127: 48-59. PMID 15306120 DOI: 10.1016/J.Molbrainres.2004.05.004  0.781
2004 Steeves J, Fawcett J, Tuszynski M. Report of international clinical trials workshop on spinal cord injury February 20-21, 2004, Vancouver, Canada. Spinal Cord. 42: 591-7. PMID 15303119 DOI: 10.1038/Sj.Sc.3101669  0.302
2004 Properzi F, Fawcett JW. Proteoglycans and Brain Repair News in Physiological Sciences. 19: 33-38. PMID 14739401 DOI: 10.1152/Nips.01449.2003  0.447
2004 Lawrence JM, Keegan DJ, Muir EM, Coffey PJ, Rogers JH, Wilby MJ, Fawcett JW, Lund RD. Transplantation of Schwann cell line clones secreting GDNF or BDNF into the retinas of dystrophic Royal College of Surgeons rats. Investigative Ophthalmology & Visual Science. 45: 267-74. PMID 14691183 DOI: 10.1167/Iovs.03-0093  0.721
2004 Rhodes KE, Fawcett JW. Chondroitin sulphate proteoglycans: Preventing plasticity or protecting the CNS? Journal of Anatomy. 204: 33-48. PMID 14690476 DOI: 10.1111/J.1469-7580.2004.00261.X  0.56
2004 Fawcett J. The role of proteoglycans in regeneration and plasticity International Journal of Experimental Pathology. 85: A55-A55. DOI: 10.1111/J.0959-9673.2004.0390L.X  0.532
2003 Dobbertin A, Rhodes KE, Garwood J, Properzi F, Heck N, Rogers JH, Fawcett JW, Faissner A. Regulation of RPTPβ/phosphacan expression and glycosaminoglycan epitopes in injured brain and cytokine-treated glia Molecular and Cellular Neuroscience. 24: 951-971. PMID 14697661 DOI: 10.1016/S1044-7431(03)00257-4  0.818
2003 Shearer MC, Niclou SP, Brown D, Asher RA, Holtmaat AJ, Levine JM, Verhaagen J, Fawcett JW. The astrocyte/meningeal cell interface is a barrier to neurite outgrowth which can be overcome by manipulation of inhibitory molecules or axonal signalling pathways. Molecular and Cellular Neurosciences. 24: 913-25. PMID 14697658 DOI: 10.1016/J.Mcn.2003.09.004  0.856
2003 Morgenstern DA, Asher RA, Naidu M, Carlstedt T, Levine JM, Fawcett JW. Expression and glycanation of the NG2 proteoglycan in developing, adult, and damaged peripheral nerve. Molecular and Cellular Neurosciences. 24: 787-802. PMID 14664826 DOI: 10.1016/S1044-7431(03)00245-8  0.805
2003 Rogers JH, Rhodes K, Roberts S, Raza M, Muir EM, Fawcett JW, Scarpini CG, Efstathiou S. A herpesvirus vector can transduce axotomized brain neurons Experimental Neurology. 183: 548-558. PMID 14552896 DOI: 10.1016/S0014-4886(03)00187-0  0.783
2003 Rhodes KE, Moon LD, Fawcett JW. Inhibiting cell proliferation during formation of the glial scar: effects on axon regeneration in the CNS. Neuroscience. 120: 41-56. PMID 12849739 DOI: 10.1016/S0306-4522(03)00285-9  0.76
2003 Properzi F, Asher RA, Fawcett JW. Chondroitin sulphate proteoglycans in the central nervous system: Changes and synthesis after injury Biochemical Society Transactions. 31: 335-336. PMID 12653631 DOI: 10.1042/Bst0310335  0.717
2003 Heck N, Garwood J, Schütte K, Fawcett J, Faissner A. Astrocytes in culture express fibrillar collagen. Glia. 41: 382-92. PMID 12555205 DOI: 10.1002/Glia.10184  0.326
2003 Moon LD, Asher RA, Fawcett JW. Limited growth of severed CNS axons after treatment of adult rat brain with hyaluronidase. Journal of Neuroscience Research. 71: 23-37. PMID 12478611 DOI: 10.1002/Jnr.10449  0.85
2002 Zietlow R, Sinclair SR, Schwiening CJ, Dunnett SB, Fawcett JW. The Release of Excitatory Amino Acids, Dopamine, and Potassium following Transplantation of Embryonic Mesencephalic Dopaminergic Grafts to the Rat Striatum, and Their Effects on Dopaminergic Neuronal Survival In Vitro. Cell Transplantation. 11: 637-652. PMID 28871871 DOI: 10.3727/000000002783985396  0.785
2002 Fawcett J. Repair of spinal cord injuries: Where are we, where are we going? Spinal Cord. 40: 615-623. PMID 12483491 DOI: 10.1038/Sj.Sc.3101328  0.393
2002 Morgenstern DA, Asher RA, Fawcett JW. Chondroitin sulphate proteoglycans in the CNS injury response Progress in Brain Research. 137: 313-332. PMID 12440375 DOI: 10.1016/S0079-6123(02)37024-9  0.794
2002 Pizzorusso T, Medini P, Berardi N, Chierzi S, Fawcett JW, Maffei L. Reactivation of ocular dominance plasticity in the adult visual cortex. Science (New York, N.Y.). 298: 1248-51. PMID 12424383 DOI: 10.1126/Science.1072699  0.349
2002 Muir EM, Adcock KH, Morgenstern DA, Clayton R, Von Stillfried N, Rhodes K, Ellis C, Fawcett JW, Rogers JH. Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes Molecular Brain Research. 100: 103-117. PMID 12008026 DOI: 10.1016/S0169-328X(02)00132-8  0.817
2002 Bradbury EJ, Moon LD, Popat RJ, King VR, Bennett GS, Patel PN, Fawcett JW, McMahon SB. Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature. 416: 636-40. PMID 11948352 DOI: 10.1038/416636A  0.792
2002 Geller HM, Fawcett JW. Building a bridge: engineering spinal cord repair. Experimental Neurology. 174: 125-36. PMID 11922655 DOI: 10.1006/Exnr.2002.7865  0.496
2002 Asher RA, Morgenstern DA, Shearer MC, Adcock KH, Pesheva P, Fawcett JW. Versican is upregulated in CNS injury and is a product of oligodendrocyte lineage cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2225-36. PMID 11896162 DOI: 10.1523/Jneurosci.22-06-02225.2002  0.838
2002 Moon LD, Asher RA, Rhodes KE, Fawcett JW. Relationship between sprouting axons, proteoglycans and glial cells following unilateral nigrostriatal axotomy in the adult rat. Neuroscience. 109: 101-17. PMID 11784703 DOI: 10.1016/S0306-4522(01)00457-2  0.839
2002 Shearer MC, Fawcett JW. The astrocyte/meningeal cell interface--a barrier to successful nerve regeneration? Cell and Tissue Research. 305: 267-73. PMID 11545264 DOI: 10.1007/S004410100384  0.842
2001 Moon LD, Fawcett JW. Reduction in CNS scar formation without concomitant increase in axon regeneration following treatment of adult rat brain with a combination of antibodies to TGFbeta1 and beta2. The European Journal of Neuroscience. 14: 1667-77. PMID 11860461 DOI: 10.1046/J.0953-816X.2001.01795.X  0.776
2001 Schnädelbach O, Fawcett JW. Astrocyte influences on oligodendrocyte progenitor migration. Progress in Brain Research. 132: 97-102. PMID 11545034 DOI: 10.1016/S0079-6123(01)32068-X  0.352
2001 Asher RA, Morgenstern DA, Moon LD, Fawcett JW. Chondroitin sulphate proteoglycans: inhibitory components of the glial scar. Progress in Brain Research. 132: 611-9. PMID 11545024 DOI: 10.1016/S0079-6123(01)32106-4  0.781
2001 Milner R, Relvas JB, Fawcett J, ffrench-Constant C. Developmental regulation of alphav integrins produces functional changes in astrocyte behavior. Molecular and Cellular Neurosciences. 18: 108-18. PMID 11461157 DOI: 10.1006/Mcne.2001.1003  0.325
2001 Schnädelbach O, Ozen I, Blaschuk OW, Meyer RL, Fawcett JW. N-cadherin is involved in axon-oligodendrocyte contact and myelination. Molecular and Cellular Neurosciences. 17: 1084-93. PMID 11414796 DOI: 10.1006/Mcne.2001.0961  0.503
2001 Moon LD, Asher RA, Rhodes KE, Fawcett JW. Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC. Nature Neuroscience. 4: 465-6. PMID 11319553 DOI: 10.1038/87415  0.84
2001 Levine JM, Reynolds R, Fawcett JW. The oligodendrocyte precursor cell in health and disease Trends in Neurosciences. 24: 39-47. PMID 11163886 DOI: 10.1016/S0166-2236(00)01691-X  0.494
2000 Iwashita Y, Fawcett JW, Crang AJ, Franklin RJ, Blakemore WF. Schwann cells transplanted into normal and X-irradiated adult white matter do not migrate extensively and show poor long-term survival. Experimental Neurology. 164: 292-302. PMID 10915568 DOI: 10.1006/Exnr.2000.7440  0.401
2000 Schnädelbach O, Blaschuk OW, Symonds M, Gour BJ, Doherty P, Fawcett JW. N-Cadherin influences migration of oligodendrocytes on astrocyte monolayers Molecular and Cellular Neurosciences. 15: 288-302. PMID 10736205 DOI: 10.1006/Mcne.1999.0819  0.395
2000 Asher RA, Morgenstern DA, Fidler PS, Adcock KH, Oohira A, Braistead JE, Levine JM, Margolis RU, Rogers JH, Fawcett JW. Neurocan is upregulated in injured brain and in cytokine-treated astrocytes Journal of Neuroscience. 20: 2427-2438. PMID 10729323 DOI: 10.1523/Jneurosci.20-07-02427.2000  0.854
2000 Moon LD, Brecknell JE, Franklin RJ, Dunnett SB, Fawcett JW. Robust regeneration of CNS axons through a track depleted of CNS glia. Experimental Neurology. 161: 49-66. PMID 10683273 DOI: 10.1006/Exnr.1999.7230  0.838
1999 Sinclair SR, Fawcett JW, Dunnett SB. Dopamine cells in nigral grafts differentiate prior to implantation. The European Journal of Neuroscience. 11: 4341-8. PMID 10594660 DOI: 10.1046/J.1460-9568.1999.00867.X  0.788
1999 Fidler PS, Schuette K, Asher RA, Dobbertin A, Thornton SR, Calle-Patino Y, Muir E, Levine JM, Geller HM, Rogers JH, Faissner A, Fawcett JW. Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: the major axon-inhibitory proteoglycan is NG2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 8778-88. PMID 10516297 DOI: 10.1523/Jneurosci.19-20-08778.1999  0.845
1999 Keirstead HS, Morgan SV, Wilby MJ, Fawcett JW. Enhanced axonal regeneration following combined demyelination plus schwann cell transplantation therapy in the injured adult spinal cord. Experimental Neurology. 159: 225-36. PMID 10486190 DOI: 10.1006/Exnr.1999.7100  0.54
1999 Fawcett JW, Asher RA. The glial scar and central nervous system repair. Brain Research Bulletin. 49: 377-91. PMID 10483914 DOI: 10.1016/S0361-9230(99)00072-6  0.73
1999 Wilby MJ, Muir EM, Fok-Seang J, Gour BJ, Blaschuk OW, Fawcett JW. N-Cadherin inhibits Schwann cell migration on astrocytes. Molecular and Cellular Neurosciences. 14: 66-84. PMID 10433818 DOI: 10.1006/Mcne.1999.0766  0.391
1999 Sinclair SR, Fawcett JW, Dunnett SB. Delayed implantation of nigral grafts improves survival of dopamine neurones and rate of functional recovery. Neuroreport. 10: 1263-7. PMID 10363936 DOI: 10.1097/00001756-199904260-00020  0.783
1999 Vogelezang MG, Scherer SS, Fawcett JW, ffrench-Constant C. Regulation of fibronectin alternative splicing during peripheral nerve repair. Journal of Neuroscience Research. 56: 323-33. PMID 10340741 DOI: 10.1002/(Sici)1097-4547(19990515)56:4<323::Aid-Jnr1>3.0.Co;2-6  0.445
1999 Zietlow R, Dunnett SB, Fawcett JW. The effect of microglia on embryonic dopaminergic neuronal survival in vitro: diffusible signals from neurons and glia change microglia from neurotoxic to neuroprotective. The European Journal of Neuroscience. 11: 1657-67. PMID 10215919 DOI: 10.1046/J.1460-9568.1999.00583.X  0.622
1999 Zietlow R, Dunnett SB, Fawcett JW. Addition of fresh blood to intrastriatal grafts of embryonic mesencephalon into the hemiparkinsonian rat does not impair the survival of grafted dopaminergic neurones. Experimental Neurology. 156: 205-8. PMID 10192791 DOI: 10.1006/Exnr.1998.6987  0.596
1999 Wilby MJ, Sinclair SR, Muir EM, Zietlow R, Adcock KH, Horellou P, Rogers JH, Dunnett SB, Fawcett JW. A glial cell line-derived neurotrophic factor-secreting clone of the Schwann cell line SCTM41 enhances survival and fiber outgrowth from embryonic nigral neurons grafted to the striatum and to the lesioned substantia nigra. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 2301-12. PMID 10066280 DOI: 10.1523/Jneurosci.19-06-02301.1999  0.82
1999 Fawcett JW. Spinal cord repair: from experimental models to human application. Spinal Cord. 36: 811-7. PMID 9881728 DOI: 10.1038/Sj.Sc.3100769  0.434
1999 Fidler PS, Schuette K, Asher RA, Dobbertin A, Thornton SR, Calle-Patino Y, Muir E, Levine JM, Geller HM, Rogers JH, Faissner A, Fawcett JW. Comparing Astrocytic Cell Lines that Are Inhibitory or Permissive for Axon Growth: the Major Axon-Inhibitory Proteoglycan Is NG2 The Journal of Neuroscience. 19: 8778-8788. DOI: 10.1523/JNEUROSCI.19-20-08778.1999  0.772
1998 Fok-Seang J, DiProspero NA, Meiners S, Muir E, Fawcett JW. Cytokine-induced changes in the ability of astrocytes to support migration of oligodendrocyte precursors and axon growth. The European Journal of Neuroscience. 10: 2400-15. PMID 9749768 DOI: 10.1046/J.1460-9568.1998.00251.X  0.517
1998 Fawcett JW, Geller HM. Regeneration in the CNS: optimism mounts. Trends in Neurosciences. 21: 179-80. PMID 9610878 DOI: 10.1016/S0166-2236(98)01241-7  0.318
1998 Muir E, Du JS, Fok-Seang J, Smith-Thomas LC, Housden ES, Rogers J, Fawcett JW. Increased axon growth through astrocyte cell lines transfected with urokinase. Glia. 23: 24-34. PMID 9562182 DOI: 10.1002/(Sici)1098-1136(199805)23:1<24::Aid-Glia3>3.0.Co;2-4  0.504
1997 Powell EM, Fawcett JW, Geller HM. Proteoglycans provide neurite guidance at an astrocyte boundary. Molecular and Cellular Neurosciences. 10: 27-42. PMID 9361286 DOI: 10.1006/Mcne.1997.0629  0.308
1997 Fawcett JW. Astrocytic and neuronal factors affecting axon regeneration in the damaged central nervous system. Cell and Tissue Research. 290: 371-7. PMID 9321700 DOI: 10.1007/S004410050943  0.563
1997 Majdan M, Lachance C, Gloster A, Aloyz R, Zeindler C, Bamji S, Bhakar A, Belliveau D, Fawcett J, Miller FD, Barker PA. Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6988-98. PMID 9278534 DOI: 10.1523/Jneurosci.17-18-06988.1997  0.329
1997 Milner R, Wilby M, Nishimura S, Boylen K, Edwards G, Fawcett J, Streuli C, Pytela R, ffrench-Constant C. Division of labor of Schwann cell integrins during migration on peripheral nerve extracellular matrix ligands. Developmental Biology. 185: 215-28. PMID 9187084 DOI: 10.1006/Dbio.1997.8547  0.718
1996 Sinclair SR, Svendsen CN, Torres EM, Martin D, Fawcett JW, Dunnett SB. GDNF enhances dopaminergic cell survival and fibre outgrowth in embryonic nigral grafts. Neuroreport. 7: 2547-52. PMID 8981421 DOI: 10.1097/00001756-199611040-00029  0.789
1996 Fricker RA, Barker RA, Fawcett JW, Dunnett SB. A comparative study of preparation techniques for improving the viability of striatal grafts using vital stains, in vitro cultures, and in vivo grafts. Cell Transplantation. 5: 599-611. PMID 8951218 DOI: 10.1016/S0963-6897(96)00087-5  0.597
1996 Brecknell JE, Du JS, Muir E, Fidler PS, Hlavin ML, Dunnett SB, Fawcett JW. Bridge grafts of fibroblast growth factor-4-secreting schwannoma cells promote functional axonal regeneration in the nigrostriatal pathway of the adult rat. Neuroscience. 74: 775-84. PMID 8884773 DOI: 10.1016/0306-4522(96)00167-4  0.84
1996 Barker RA, Dunnett SB, Faissner A, Fawcett JW. The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum. Experimental Neurology. 141: 79-93. PMID 8797670 DOI: 10.1006/Exnr.1996.0141  0.633
1996 Haque NS, Hlavin ML, Fawcett JW, Dunnett SB. The neurotrophin NT4/5, but not NT3, enhances the efficacy of nigral grafts in a rat model of Parkinson's disease. Brain Research. 712: 45-52. PMID 8705306 DOI: 10.1016/0006-8993(95)01427-6  0.618
1996 Brecknell JE, Haque NS, Du JS, Muir EM, Fidler PS, Hlavin ML, Fawcett JW, Dunnett SB. Functional and anatomical reconstruction of the 6-hydroxydopamine lesioned nigrostriatal system of the adult rat. Neuroscience. 71: 913-25. PMID 8684622 DOI: 10.1016/0306-4522(95)00509-9  0.789
1996 Brecknell JE, Fawcett JW. A device for the implantation of multiple cellular deposits into a large volume of brain from a single cannula site. Experimental Neurology. 138: 338-44. PMID 8620932 DOI: 10.1006/Exnr.1996.0072  0.303
1996 Brecknell JE, Fawcett JW. Axonal regeneration. Biological Reviews of the Cambridge Philosophical Society. 71: 227-55. PMID 8616210 DOI: 10.1111/j.1469-185x.1996.tb00748.x  0.475
1995 Haque NS, Hlavin ML, Du JS, Fawcett JW, Dunnett SB. In vivo effects of kFGF on embryonic nigral grafts in a rat model of Parkinson's disease. Neuroreport. 6: 2177-81. PMID 8595197 DOI: 10.1097/00001756-199511000-00019  0.596
1995 Fawcett JW, Barker RA, Dunnett SB. Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon. Experimental Brain Research. 106: 275-82. PMID 8566192 DOI: 10.1007/Bf00241123  0.614
1995 Fawcett J. Spinal cord transplants: A future treatment for spinal injury? Paraplegia. 33: 491-492. PMID 8524600 DOI: 10.1038/Sc.1995.108  0.316
1995 Svendsen CN, Fawcett JW, Bentlage C, Dunnett SB. Increased survival of rat EGF-generated CNS precursor cells using B27 supplemented medium. Experimental Brain Research. 102: 407-14. PMID 7737387 DOI: 10.1007/Bf00230645  0.614
1995 Brecknell JE, Dunnett SB, Fawcett JW. A quantitative study of cell death in the substantia nigra following a mechanical lesion of the medial forebrain bundle. Neuroscience. 64: 219-27. PMID 7708207 DOI: 10.1016/0306-4522(94)00370-K  0.617
1995 Fok-Seang J, Mathews GA, ffrench-Constant C, Trotter J, Fawcett JW. Migration of oligodendrocyte precursors on astrocytes and meningeal cells. Developmental Biology. 171: 1-15. PMID 7556887 DOI: 10.1006/Dbio.1995.1255  0.383
1995 Barker RA, Fricker RA, Abrous DN, Fawcett J, Dunnett SB. A comparative study of preparation techniques for improving the viability of nigral grafts using vital stains, in vitro cultures, and in vivo grafts. Cell Transplantation. 4: 173-200. PMID 7539699  0.546
1994 Bunch ST, Fawcett JW. NMDA receptor blockade alters the topography of naturally occurring ganglion cell death in the rat retina. Developmental Biology. 160: 434-42. PMID 8253276 DOI: 10.1006/Dbio.1993.1319  0.411
1994 Fawcett JW, Mathews G, Housden E, Goedert M, Matus A. Regenerating sciatic nerve axons contain the adult rather than the embryonic pattern of microtubule associated proteins. Neuroscience. 61: 789-804. PMID 7838378 DOI: 10.1016/0306-4522(94)90402-2  0.504
1994 Fawcett J. Astrocytes and axon regeneration in the central nervous system Journal of Neurology. 242. PMID 7699404 DOI: 10.1007/Bf00939237  0.544
1993 Mayer E, Fawcett JW, Dunnett SB. Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--II. Effects on nigral transplants in vivo. Neuroscience. 56: 389-98. PMID 8247268 DOI: 10.1016/0306-4522(93)90340-L  0.601
1993 Mayer E, Dunnett SB, Fawcett JW. Mitogenic effect of basic fibroblast growth factor on embryonic ventral mesencephalic dopaminergic neurone precursors. Brain Research. Developmental Brain Research. 72: 253-8. PMID 8097973 DOI: 10.1016/0165-3806(93)90190-L  0.605
1993 Mayer E, Dunnett SB, Pellitteri R, Fawcett JW. Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons--I. Effects in vitro. Neuroscience. 56: 379-88. PMID 7902540 DOI: 10.1016/0306-4522(93)90339-H  0.621
1993 Barker R, Dunnett S, Fawcett J. Immunohistochemical identification of rat adrenal cortical tissue in situ, in vitro, and in intracerebral adrenal grafts. Experimental Neurology. 122: 125-9. PMID 7687964 DOI: 10.1006/Exnr.1993.1113  0.581
1993 Barker R, Dunnett S, Fawcett J. A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro. Experimental Brain Research. 92: 467-72. PMID 7681011 DOI: 10.1007/Bf00229034  0.609
1993 Barker RA, Dunnett SB, Fawcett JW. Neurotrophic factors and neural grafts: a growing field Seminars in Neuroscience. 5: 431-441. DOI: 10.1016/S1044-5765(05)80015-6  0.582
1992 Fawcett JW. Spinal cord repair: future directions. Paraplegia. 30: 83-5. PMID 1589293 DOI: 10.1038/Sc.1992.29  0.463
1992 Fawcett JW. Intrinsic neuronal determinants of regeneration. Trends in Neurosciences. 15: 5-8. PMID 1374956 DOI: 10.1016/0166-2236(92)90338-9  0.512
1991 Fawcett JW. Factors influencing the regeneration of axons in the central nervous system. Paraplegia. 29: 287-93. PMID 1886727 DOI: 10.1038/Sc.1991.42  0.529
1991 Feneley MR, Fawcett JW, Keynes RJ. The role of Schwann cells in the regeneration of peripheral nerve axons through muscle basal lamina grafts. Experimental Neurology. 114: 275-85. PMID 1748202 DOI: 10.1016/0014-4886(91)90153-4  0.47
1991 Abnet K, Fawcett JW, Dunnett SB. Interactions between meningeal cells and astrocytes in vivo and in vitro. Brain Research. Developmental Brain Research. 59: 187-96. PMID 1717179 DOI: 10.1016/0165-3806(91)90099-5  0.632
1990 Bunch ST, Fawcett JW. A comparison of the initial retinal ganglion cell projection to the contralateral superior colliculus in albino and pigmented rats. Brain Research. Developmental Brain Research. 52: 259-64. PMID 2331794 DOI: 10.1016/0165-3806(90)90243-R  0.35
1990 Fawcett JW, Keynes RJ. Peripheral nerve regeneration. Annual Review of Neuroscience. 13: 43-60. PMID 2183684 DOI: 10.1146/Annurev.Ne.13.030190.000355  0.391
1989 Fawcett JW, Housden E, Smith-Thomas L, Meyer RL. The growth of axons in three-dimensional astrocyte cultures. Developmental Biology. 135: 449-58. PMID 2776978 DOI: 10.1016/0012-1606(89)90193-0  0.503
1988 Udin SB, Fawcett JW. Formation of topographic maps. Annual Review of Neuroscience. 11: 289-327. PMID 3284443 DOI: 10.1146/Annurev.Ne.11.030188.001445  0.496
1986 O'Leary DD, Crespo D, Fawcett JW, Cowan WM. The effect of intraocular tetrodotoxin on the postnatal reduction in the numbers of optic nerve axons in the rat. Brain Research. 395: 96-103. PMID 3779435 DOI: 10.1016/0165-3806(86)90136-7  0.736
1986 Fawcett JW, Keynes RJ. Muscle basal lamina: a new graft material for peripheral nerve repair. Journal of Neurosurgery. 65: 354-63. PMID 3734886 DOI: 10.3171/Jns.1986.65.3.0354  0.363
1986 O'Leary D, Fawcett J, Cowan W. Topographic targeting errors in the retinocollicular projection and their elimination by selective ganglion cell death The Journal of Neuroscience. 6: 3692-3705. DOI: 10.1523/Jneurosci.06-12-03692.1986  0.427
1985 Fawcett JW, Cowan WM. On the formation of eye dominance stripes and patches in the doubly-innervated optic tectum of the chick. Brain Research. 349: 147-63. PMID 3986583 DOI: 10.1016/0165-3806(85)90139-7  0.519
1985 Fawcett JW, O'Leary DD. The role of electrical activity in the formation of topographic maps in the nervous system Trends in Neurosciences. 8: 201-206. DOI: 10.1016/0166-2236(85)90079-7  0.592
1984 Fawcett JW, O'Leary DD, Cowan WM. Activity and the control of ganglion cell death in the rat retina. Proceedings of the National Academy of Sciences of the United States of America. 81: 5589-93. PMID 6591206 DOI: 10.1073/Pnas.81.17.5589  0.672
1984 Cowan WM, Fawcett JW, O'Leary DD, Stanfield BB. Regressive events in neurogenesis. Science (New York, N.Y.). 225: 1258-65. PMID 6474175 DOI: 10.1126/Science.6474175  0.755
1982 Fawcett JW, Willshaw DJ. Compound eyes project stripes on the optic tectum in Xenopus. Nature. 296: 350-1. PMID 7063032 DOI: 10.1038/296350A0  0.579
1981 Fawcett JW, Gaze RM. The organization of regenerating axons in the Xenopus optic nerve. Brain Research. 229: 487-90. PMID 7306821 DOI: 10.1016/0006-8993(81)91009-X  0.647
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