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Alex C. Kwan, Ph.D. - Publications

Affiliations: 
2013-2022 Psychiatry Yale University School of Medicine, New Haven, CT 
 2022- Biomedical Engineering Cornell University, Ithaca, NY, United States 
Website:
http://alexkwanlab.org
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Glaeser-Khan S, Savalia NK, Cressy J, Feng J, Li Y, Kwan AC, Kaye AP. Spatiotemporal organization of prefrontal norepinephrine influences neuronal activity. Biorxiv : the Preprint Server For Biology. PMID 37502881 DOI: 10.1101/2023.06.09.544191  0.737
2023 Woodburn SC, Kwan AC. Timing is key for behavioural benefits of psychedelics. Nature. 618: 677-678. PMID 37316593 DOI: 10.1038/d41586-023-01869-2  0.728
2023 Kaye AP, Rao MG, Kwan AC, Ressler KJ, Krystal JH. A computational model for learning from repeated traumatic experiences under uncertainty. Cognitive, Affective & Behavioral Neuroscience. PMID 37165181 DOI: 10.3758/s13415-023-01085-5  0.746
2023 Jefferson SJ, Gregg I, Dibbs M, Liao C, Wu H, Davoudian PA, Woodburn SC, Wehrle PH, Sprouse JS, Sherwood AM, Kaye AP, Pittenger C, Kwan AC. 5-MeO-DMT modifies innate behaviors and promotes structural neural plasticity in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37015972 DOI: 10.1038/s41386-023-01572-w  0.735
2022 Wang H, Ortega HK, Atilgan H, Murphy CE, Kwan AC. Pupil correlates of decision variables in mice playing a competitive mixed-strategy game. Eneuro. PMID 35168951 DOI: 10.1523/ENEURO.0457-21.2022  0.287
2022 Kelmendi B, Kaye AP, Pittenger C, Kwan AC. Psychedelics. Current Biology : Cb. 32: R63-R67. PMID 35077687 DOI: 10.1016/j.cub.2021.12.009  0.747
2021 Ortega HK, Kwan AC. A visuomotor microcircuit in frontal cortex. Nature Neuroscience. PMID 34413511 DOI: 10.1038/s41593-021-00915-4  0.313
2021 Rupprecht P, Carta S, Hoffmann A, Echizen M, Blot A, Kwan AC, Dan Y, Hofer SB, Kitamura K, Helmchen F, Friedrich RW. A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging. Nature Neuroscience. PMID 34341584 DOI: 10.1038/s41593-021-00895-5  0.473
2021 Shao LX, Liao C, Gregg I, Davoudian PA, Savalia NK, Delagarza K, Kwan AC. Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo. Neuron. PMID 34228959 DOI: 10.1016/j.neuron.2021.06.008  0.797
2021 Wu H, Savalia NK, Kwan AC. Ketamine for a Boost of Neural Plasticity: How, but Also When? Biological Psychiatry. 89: 1030-1032. PMID 34016377 DOI: 10.1016/j.biopsych.2021.03.014  0.76
2021 Yang JH, Kwan AC. Secondary motor cortex: Broadcasting and biasing animal's decisions through long-range circuits. International Review of Neurobiology. 158: 443-470. PMID 33785155 DOI: 10.1016/bs.irn.2020.11.008  0.755
2021 Liao C, Kwan AC. Applying Reinforcement Learning to Rodent Stress Research. Chronic Stress (Thousand Oaks, Calif.). 5: 2470547020984732. PMID 33598593 DOI: 10.1177/2470547020984732  0.297
2021 Ali F, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Author Correction: Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines. Nature Communications. 12: 370. PMID 33420087 DOI: 10.1038/s41467-020-20634-x  0.277
2020 Savalia NK, Shao LX, Kwan AC. A Dendrite-Focused Framework for Understanding the Actions of Ketamine and Psychedelics. Trends in Neurosciences. PMID 33358035 DOI: 10.1016/j.tins.2020.11.008  0.774
2020 Zhu PK, Zheng WS, Zhang P, Jing M, Borden PM, Ali F, Guo K, Feng J, Marvin JS, Wang Y, Wan J, Gan L, Kwan AC, Lin L, Looger LL, et al. Nanoscopic Visualization of Restricted Nonvolume Cholinergic and Monoaminergic Transmission with Genetically Encoded Sensors. Nano Letters. PMID 32396366 DOI: 10.1021/Acs.Nanolett.9B04877  0.385
2020 Barthas F, Hu MY, Siniscalchi MJ, Ali F, Mineur YS, Picciotto MR, Kwan AC. Cumulative Effects of Social Stress on Reward-Guided Actions and Prefrontal Cortical Activity. Biological Psychiatry. PMID 32276717 DOI: 10.1016/J.Biopsych.2020.02.008  0.773
2020 Ali F, Shao LX, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromise by a nonsense Shank3 mutation. Molecular Psychiatry. PMID 32161363 DOI: 10.1038/S41380-020-0708-6  0.413
2020 Ali F, Gerhard DM, Sweasy K, Pothula S, Pittenger C, Duman RS, Kwan AC. Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines. Nature Communications. 11: 72. PMID 31911591 DOI: 10.1038/S41467-019-13809-8  0.474
2020 Ali F, Kwan AC. Interpreting calcium signals from neuronal cell bodies, axons, and dendrites: a review. Neurophotonics. 7: 011402. PMID 31372367 DOI: 10.1117/1.Nph.7.1.011402  0.407
2020 Kwan AC, Petersen CC. Decision letter: Control of adaptive action selection by secondary motor cortex during flexible visual categorization Elife. DOI: 10.7554/Elife.54474.Sa1  0.407
2020 Kaye A, Cressy J, Feng J, Li Y, Kwan A. Prefrontal Norepinephrine and Acetylcholine Dynamics Structure Arousal After Stress Biological Psychiatry. 87: S123. DOI: 10.1016/J.Biopsych.2020.02.333  0.749
2019 Ali F, Baringer SL, Neal A, Choi EY, Kwan AC. Parvalbumin-Positive Neuron Loss and Amyloid-β Deposits in the Frontal Cortex of Alzheimer's Disease-Related Mice. Journal of Alzheimer's Disease : Jad. PMID 31743995 DOI: 10.3233/Jad-181190  0.419
2019 Siniscalchi MJ, Wang H, Kwan AC. Enhanced Population Coding for Rewarded Choices in the Medial Frontal Cortex of the Mouse. Cerebral Cortex (New York, N.Y. : 1991). PMID 30615132 DOI: 10.1093/Cercor/Bhy292  0.771
2019 Kwan AC, Donahue CH. Decision letter: Balancing model-based and memory-free action selection under competitive pressure Elife. DOI: 10.7554/Elife.48810.028  0.337
2019 Kaye A, Rao M, Kwan A. F39. Stress Speeds Arousal Fluctuations In mPFC Neurons and Pupillary Diameter Biological Psychiatry. 85: S227. DOI: 10.1016/J.Biopsych.2019.03.576  0.753
2018 Atilgan H, Kwan AC. Same lesson, varied choices by frontal cortex. Nature Neuroscience. PMID 30420733 DOI: 10.1038/S41593-018-0282-2  0.442
2018 Kaye A, Rao M, Kwan A. F13. Arousal and mPFC Activity in a Mouse Model of Acute Traumatic Stress Biological Psychiatry. 83: S242. DOI: 10.1016/J.Biopsych.2018.02.626  0.743
2018 Kaye A, Kwan A. T17. The Role of mPFC in Escape From an Innate Fear Stimulus Biological Psychiatry. 83: S135. DOI: 10.1016/J.Biopsych.2018.02.353  0.73
2017 Hill RA, Damisah EC, Chen F, Kwan AC, Grutzendler J. Targeted two-photon chemical apoptotic ablation of defined cell types in vivo. Nature Communications. 8: 15837. PMID 28621306 DOI: 10.1038/Ncomms15837  0.376
2016 Barthas F, Kwan AC. Secondary Motor Cortex: Where 'Sensory' Meets 'Motor' in the Rodent Frontal Cortex. Trends in Neurosciences. PMID 28012708 DOI: 10.1016/J.Tins.2016.11.006  0.446
2016 Siniscalchi MJ, Phoumthipphavong V, Ali F, Lozano M, Kwan AC. Fast and slow transitions in frontal ensemble activity during flexible sensorimotor behavior. Nature Neuroscience. PMID 27399844 DOI: 10.1038/Nn.4342  0.778
2016 Phoumthipphavong V, Barthas F, Hassett S, Kwan AC. Longitudinal Effects of Ketamine on Dendritic Architecture In Vivo in the Mouse Medial Frontal Cortex. Eneuro. 3. PMID 27066532 DOI: 10.1523/ENEURO.0133-15.2016  0.377
2014 Lee SH, Kwan AC, Dan Y. Interneuron subtypes and orientation tuning. Nature. 508: E1-2. PMID 24695313 DOI: 10.1038/Nature13128  0.623
2013 Pinto L, Goard MJ, Estandian D, Xu M, Kwan AC, Lee SH, Harrison TC, Feng G, Dan Y. Fast modulation of visual perception by basal forebrain cholinergic neurons. Nature Neuroscience. 16: 1857-63. PMID 24162654 DOI: 10.1038/Nn.3552  0.769
2012 Lee SH, Kwan AC, Zhang S, Phoumthipphavong V, Flannery JG, Masmanidis SC, Taniguchi H, Huang ZJ, Zhang F, Boyden ES, Deisseroth K, Dan Y. Activation of specific interneurons improves V1 feature selectivity and visual perception. Nature. 488: 379-83. PMID 22878719 DOI: 10.1038/Nature11312  0.757
2012 Kwan AC, Dan Y. Dissection of cortical microcircuits by single-neuron stimulation in vivo. Current Biology : Cb. 22: 1459-67. PMID 22748320 DOI: 10.1016/J.Cub.2012.06.007  0.591
2011 Yuen D, Wu X, Kwan AC, Ledue J, Zhang H, Ecoiffier T, Pytowski B, Chen L. Live imaging of newly formed lymphatic vessels in the cornea. Cell Research. 21: 1745-9. PMID 22083511 DOI: 10.1038/Cr.2011.178  0.309
2011 Kadiri LR, Kwan AC, Webb WW, Harris-Warrick RM. Dopamine-induced oscillations of the pyloric pacemaker neuron rely on release of calcium from intracellular stores. Journal of Neurophysiology. 106: 1288-98. PMID 21676929 DOI: 10.1152/Jn.00456.2011  0.555
2011 McMullen JD, Kwan AC, Williams RM, Zipfel WR. Enhancing collection efficiency in large field of view multiphoton microscopy. Journal of Microscopy. 241: 119-24. PMID 21118215 DOI: 10.1111/J.1365-2818.2010.03419.X  0.571
2010 Kwan AC, Dietz SB, Zhong G, Harris-Warrick RM, Webb WW. Spatiotemporal dynamics of rhythmic spinal interneurons measured with two-photon calcium imaging and coherence analysis. Journal of Neurophysiology. 104: 3323-33. PMID 20861442 DOI: 10.1152/Jn.00679.2010  0.558
2010 Kwan AC. Toward reconstructing spike trains from large-scale calcium imaging data. Hfsp Journal. 4: 1-5. PMID 20676302 DOI: 10.2976/1.3284977  0.384
2010 Zhong G, Droho S, Crone SA, Dietz S, Kwan AC, Webb WW, Sharma K, Harris-Warrick RM. Electrophysiological characterization of V2a interneurons and their locomotor-related activity in the neonatal mouse spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 170-82. PMID 20053899 DOI: 10.1523/Jneurosci.4849-09.2010  0.553
2009 Kwan AC, Dietz SB, Webb WW, Harris-Warrick RM. Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 11601-13. PMID 19759307 DOI: 10.1523/Jneurosci.1612-09.2009  0.516
2009 Kwan AC, Duff K, Gouras GK, Webb WW. Optical visualization of Alzheimer's pathology via multiphoton-excited intrinsic fluorescence and second harmonic generation. Optics Express. 17: 3679-89. PMID 19259208 DOI: 10.1364/Oe.17.003679  0.647
2008 Kwan AC. What can population calcium imaging tell us about neural circuits? Journal of Neurophysiology. 100: 2977-80. PMID 18829844 DOI: 10.1152/Jn.91037.2008  0.391
2008 Kwan AC, Dombeck DA, Webb WW. Polarized microtubule arrays in apical dendrites and axons. Proceedings of the National Academy of Sciences of the United States of America. 105: 11370-5. PMID 18682556 DOI: 10.1073/Pnas.0805199105  0.723
2002 DiSanto DW, Kwan AC, Bolognesi CR. Gate-to-drain separation and transistor cutoff frequency in wet etched AlGaN/GaN HFETs Electronics Letters. 38: 921-923. DOI: 10.1049/El:20020641  0.33
2002 Bolognesi CR, Kwan AC, DiSanto DW. Transistor delay analysis and effective channel velocity extraction in AlGaN/GaN HFETs Technical Digest - International Electron Devices Meeting. 685-688.  0.188
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