Amy M. Barrios - Publications

Chemistry: Doctor of Philosophy University of Southern California, Los Angeles, CA, United States 
Inorganic Chemistry, Pharmaceutical Chemistry, Biochemistry

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Thorson MK, Ung P, Leaver FM, Corbin TS, Tuck KL, Graham B, Barrios AM. Lanthanide complexes as luminogenic probes to measure sulfide levels in industrial samples. Analytica Chimica Acta. 896: 160-5. PMID 26482000 DOI: 10.1016/j.aca.2015.09.024  1
2015 Thorson MK, Van Wagoner RM, Harper MK, Ireland CM, Majtan T, Kraus JP, Barrios AM. Marine natural products as inhibitors of cystathionine beta-synthase activity. Bioorganic & Medicinal Chemistry Letters. 25: 1064-6. PMID 25666819 DOI: 10.1016/j.bmcl.2015.01.013  1
2014 Thorson MK, Puerta DT, Cohen SM, Barrios AM. Inhibition of the lymphoid tyrosine phosphatase: the effect of zinc(II) ions and chelating ligand fragments on enzymatic activity. Bioorganic & Medicinal Chemistry Letters. 24: 4019-22. PMID 24997687 DOI: 10.1016/j.bmcl.2014.06.016  1
2014 Qian Z, LaRochelle JR, Jiang B, Lian W, Hard RL, Selner NG, Luechapanichkul R, Barrios AM, Pei D. Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery. Biochemistry. 53: 4034-46. PMID 24896852 DOI: 10.1021/bi5004102  1
2014 Ahmed VF, Bottini N, Barrios AM. Covalent inhibition of the lymphoid tyrosine phosphatase. Chemmedchem. 9: 296-9. PMID 24403103 DOI: 10.1002/cmdc.201300404  1
2014 Sharlow ER, Leimgruber S, Murray S, Lira A, Sciotti RJ, Hickman M, Hudson T, Leed S, Caridha D, Barrios AM, Close D, Grögl M, Lazo JS. Auranofin is an apoptosis-simulating agent with in vitro and in vivo anti-leishmanial activity. Acs Chemical Biology. 9: 663-72. PMID 24328400 DOI: 10.1021/cb400800q  1
2014 Stanford SM, Ahmed V, Barrios AM, Bottini N. Cellular biochemistry methods for investigating protein tyrosine phosphatases. Antioxidants & Redox Signaling. 20: 2160-78. PMID 24294920 DOI: 10.1089/ars.2013.5731  1
2014 Stanford SM, Krishnamurthy D, Kulkarni RA, Karver CE, Bruenger E, Walker LM, Ma CT, Chung TD, Sergienko E, Bottini N, Barrios AM. pCAP-based peptide substrates: the new tool in the box of tyrosine phosphatase assays. Methods (San Diego, Calif.). 65: 165-74. PMID 23886911 DOI: 10.1016/j.ymeth.2013.07.022  1
2013 Kulkarni RA, Vellore NA, Bliss MR, Stanford SM, Falk MD, Bottini N, Baron R, Barrios AM. Substrate selection influences molecular recognition in a screen for lymphoid tyrosine phosphatase inhibitors. Chembiochem : a European Journal of Chemical Biology. 14: 1640-7. PMID 23956195 DOI: 10.1002/cbic.201300273  1
2013 Kulkarni RA, Stanford SM, Vellore NA, Krishnamurthy D, Bliss MR, Baron R, Bottini N, Barrios AM. Thiuram disulfides as pseudo-irreversible inhibitors of lymphoid tyrosine phosphatase. Chemmedchem. 8: 1561-8. PMID 23873737 DOI: 10.1002/cmdc.201300215  1
2013 Barrios AM, Cohen SM, Lim MH. Medicinal inorganic chemistry: a web themed issue. Chemical Communications (Cambridge, England). 49: 5910-1. PMID 23715532 DOI: 10.1039/c3cc90159a  1
2013 He Y, Liu S, Menon A, Stanford S, Oppong E, Gunawan AM, Wu L, Wu DJ, Barrios AM, Bottini N, Cato AC, Zhang ZY. A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases. Journal of Medicinal Chemistry. 56: 4990-5008. PMID 23713581 DOI: 10.1021/jm400248c  1
2013 Thorson MK, Majtan T, Kraus JP, Barrios AM. Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe. Angewandte Chemie (International Ed. in English). 52: 4641-4. PMID 23512751 DOI: 10.1002/anie.201300841  1
2013 Qian Z, Liu T, Liu YY, Briesewitz R, Barrios AM, Jhiang SM, Pei D. Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs. Acs Chemical Biology. 8: 423-31. PMID 23130658 DOI: 10.1021/cb3005275  1
2012 Stanford SM, Panchal RG, Walker LM, Wu DJ, Falk MD, Mitra S, Damle SS, Ruble D, Kaltcheva T, Zhang S, Zhang ZY, Bavari S, Barrios AM, Bottini N. High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45. Proceedings of the National Academy of Sciences of the United States of America. 109: 13972-7. PMID 22891353 DOI: 10.1073/pnas.1205028109  1
2012 Debnath A, Parsonage D, Andrade RM, He C, Cobo ER, Hirata K, Chen S, García-Rivera G, Orozco E, Martínez MB, Gunatilleke SS, Barrios AM, Arkin MR, Poole LB, McKerrow JH, et al. A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target. Nature Medicine. 18: 956-60. PMID 22610278 DOI: 10.1038/nm.2758  1
2012 Obiri DD, Flink N, Maier JV, Neeb A, Maddalo D, Thiele W, Menon A, Stassen M, Kulkarni RA, Garabedian MJ, Barrios AM, Cato ACB. PEST-domain-enriched tyrosine phosphatase and glucocorticoids as regulators of anaphylaxis in mice Allergy: European Journal of Allergy and Clinical Immunology. 67: 175-182. PMID 21981059 DOI: 10.1111/j.1398-9995.2011.02731.x  1
2011 Stanford SM, Krishnamurthy D, Falk MD, Messina R, Debnath B, Li S, Liu T, Kazemi R, Dahl R, He Y, Yu X, Chan AC, Zhang ZY, Barrios AM, Woods VL, et al. Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells. Journal of Medicinal Chemistry. 54: 1640-54. PMID 21341673 DOI: 10.1021/jm101202j  1
2011 Karver CE, Ahmed VF, Barrios AM. Oxidative inactivation of the lymphoid tyrosine phosphatase mediated by both general and active site directed NO donors. Bioorganic & Medicinal Chemistry Letters. 21: 285-7. PMID 21129966 DOI: 10.1016/j.bmcl.2010.11.025  1
2010 Karver MR, Krishnamurthy D, Bottini N, Barrios AM. Gold(I) phosphine mediated selective inhibition of lymphoid tyrosine phosphatase. Journal of Inorganic Biochemistry. 104: 268-73. PMID 20083307 DOI: 10.1016/j.jinorgbio.2009.12.012  1
2009 Karver MR, Krishnamurthy D, Kulkarni RA, Bottini N, Barrios AM. Identifying potent, selective protein tyrosine phosphatase inhibitors from a library of Au(I) complexes. Journal of Medicinal Chemistry. 52: 6912-8. PMID 19888762 DOI: 10.1021/jm901220m  1
2009 Krishnamurthy D, Barrios AM. Profiling protein tyrosine phosphatase activity with mechanistic probes. Current Opinion in Chemical Biology. 13: 375-81. PMID 19716756 DOI: 10.1016/j.cbpa.2009.07.017  1
2008 Karver MR, Barrios AM. Identifying and characterizing the biological targets of metallotherapeutics: Two approaches using Au(I)-protein interactions as model systems. Analytical Biochemistry. 382: 63-5. PMID 18692018 DOI: 10.1016/j.ab.2008.07.019  1
2008 Krishnamurthy D, Karver MR, Fiorillo E, Orrú V, Stanford SM, Bottini N, Barrios AM. Gold(I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study. Journal of Medicinal Chemistry. 51: 4790-5. PMID 18605719 DOI: 10.1021/jm800101w  1
2008 Franzman MA, Barrios AM. Spectroscopic evidence for the formation of goldfingers. Inorganic Chemistry. 47: 3928-30. PMID 18426199 DOI: 10.1021/ic800157t  1
2008 Mitra S, Barrios AM. Identifying selective protein tyrosine phosphatase substrates and inhibitors from a fluorogenic, combinatorial peptide library. Chembiochem : a European Journal of Chemical Biology. 9: 1216-9. PMID 18412190 DOI: 10.1002/cbic.200800046  1
2008 Gunatilleke SS, de Oliveira CA, McCammon JA, Barrios AM. Inhibition of cathepsin B by Au(I) complexes: a kinetic and computational study. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 555-61. PMID 18253767 DOI: 10.1007/s00775-008-0344-0  1
2008 Hubbard CE, Barrios AM. A highly efficient route to enantiomerically pure l-N-Bz-Pmp(t-Bu)2-OH and incorporation into a peptide-based protein tyrosine phosphatase inhibitor. Bioorganic & Medicinal Chemistry Letters. 18: 679-81. PMID 18240386 DOI: 10.1016/j.bmcl.2007.11.056  1
2008 Gunatilleke SS, Barrios AM. Tuning the Au(I)-mediated inhibition of cathepsin B through ligand substitutions. Journal of Inorganic Biochemistry. 102: 555-63. PMID 18164406 DOI: 10.1016/j.jinorgbio.2007.10.019  1
2007 Mitra S, Barrios AM. A series of peptide-based, fluorogenic probes for protein tyrosine phosphatase activity. Analytical Biochemistry. 370: 249-51. PMID 17662953 DOI: 10.1016/j.ab.2007.06.012  1
2006 Barrios AM. Intracellular metal detectors. Acs Chemical Biology. 1: 67-8. PMID 17163644 DOI: 10.1021/cb600080a  1
2006 Gunatilleke SS, Barrios AM. Inhibition of lysosomal cysteine proteases by a series of Au(I) complexes: a detailed mechanistic investigation. Journal of Medicinal Chemistry. 49: 3933-7. PMID 16789749 DOI: 10.1021/jm060158f  1
2005 Mitra S, Barrios AM. Highly sensitive peptide-based probes for protein tyrosine phosphatase activity utilizing a fluorogenic mimic of phosphotyrosine. Bioorganic & Medicinal Chemistry Letters. 15: 5142-5. PMID 16203147 DOI: 10.1016/j.bmcl.2005.08.054  1
2004 Chircorian A, Barrios AM. Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I). Bioorganic & Medicinal Chemistry Letters. 14: 5113-6. PMID 15380210 DOI: 10.1016/j.bmcl.2004.07.073  1
2002 Barrios AM, Craik CS. Scanning the prime-site substrate specificity of proteolytic enzymes: a novel assay based on ligand-enhanced lanthanide ion fluorescence. Bioorganic & Medicinal Chemistry Letters. 12: 3619-23. PMID 12443789 DOI: 10.1016/S0960-894X(02)00786-2  1
2001 Barrios AM, Lippard SJ. Decomposition of alkyl-substituted urea molecules at a hydroxide-bridged dinickel center Inorganic Chemistry. 40: 1250-1255. PMID 11300826 DOI: 10.1021/ic000933w  1
2001 Barrios AM, Lippard SJ. Phthalazine-based dinucleating ligands afford dinuclear centers often encountered in metalloenzyme active sites Inorganic Chemistry. 40: 1060-1064. PMID 11259020 DOI: 10.1021/ic000889k  1
2000 He C, Barrios AM, Lee D, Kuzelka J, Davydov RM, Lippard SJ. Diiron complexes of 1,8-naphthyridine-based dinucleating ligands as models for hemerythrin Journal of the American Chemical Society. 122: 12683-12690. DOI: 10.1021/ja0026861  1
2000 Barrios AM, Lippard SJ. Interaction of urea with a hydroxide-bridged dinuclear nickel center: An alternative model for the mechanism of urease Journal of the American Chemical Society. 122: 9172-9177. DOI: 10.1021/ja000202v  1
1999 LeCloux DD, Barrios AM, Lippard SJ. The reactivity of well defined diiron(III) peroxo complexes toward substrates: Addition to electrophiles and hydrocarbon oxidation Bioorganic and Medicinal Chemistry. 7: 763-772. PMID 10400329 DOI: 10.1016/S0968-0896(98)00270-3  1
1999 Barrios AM, Lippard SJ. Amide hydrolysis effected by a hydroxo-bridged dinickel(II) complex: Insights into the mechanism of urease Journal of the American Chemical Society. 121: 11751-11757. DOI: 10.1021/ja992447h  1
1998 LeCloux DD, Barrios AM, Mizoguchi TJ, Lippard SJ. Modeling the diiron centers of non-heme iron enzymes. Preparation of sterically hindered diiron(II) tetracarboxylate complexes and their reactions with dioxygen Journal of the American Chemical Society. 120: 9001-9014. DOI: 10.1021/ja981216s  1
1995 Liu G, Bruenger FW, Barrios AM, Miller SC. Synthesis of 2-Alkyl-3-Hydroxy-4-Pyridinone-Ribonucleosides, Potential Oral Iron Chelators Nucleosides and Nucleotides. 14: 1901-1904. DOI: 10.1080/15257779508010712  1
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