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Shamila S. Gunatilleke, Ph.D. - Publications

Affiliations: 
2007 Chemistry: Doctor of Philosophy University of Southern California, Los Angeles, CA, United States 
Area:
Inorganic Chemistry, Pharmaceutical Chemistry, Biochemistry
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Choi JY, Calvet CM, Vieira DF, Gunatilleke SS, Cameron MD, McKerrow JH, Podust LM, Roush WR. R-Configuration of 4-Aminopyridyl-Based Inhibitors of CYP51 Confers Superior Efficacy Against Trypanosoma cruzi. Acs Medicinal Chemistry Letters. 5: 434-9. PMID 24900854 DOI: 10.1021/Ml500010M  0.378
2013 Choi JY, Calvet CM, Gunatilleke SS, Ruiz C, Cameron MD, McKerrow JH, Podust LM, Roush WR. Rational development of 4-aminopyridyl-based inhibitors targeting Trypanosoma cruzi CYP51 as anti-chagas agents. Journal of Medicinal Chemistry. 56: 7651-68. PMID 24079662 DOI: 10.1021/Jm401067S  0.396
2013 Choy JW, Bryant C, Calvet CM, Doyle PS, Gunatilleke SS, Leung SS, Ang KK, Chen S, Gut J, Oses-Prieto JA, Johnston JB, Arkin MR, Burlingame AL, Taunton J, Jacobson MP, et al. Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target. Beilstein Journal of Organic Chemistry. 9: 15-25. PMID 23400640 DOI: 10.3762/Bjoc.9.3  0.506
2012 Debnath A, Parsonage D, Andrade RM, He C, Cobo ER, Hirata K, Chen S, García-Rivera G, Orozco E, Martínez MB, Gunatilleke SS, Barrios AM, Arkin MR, Poole LB, McKerrow JH, et al. A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target. Nature Medicine. 18: 956-60. PMID 22610278 DOI: 10.1038/Nm.2758  0.559
2011 Carlson JC, Li S, Gunatilleke SS, Anzai Y, Burr DA, Podust LM, Sherman DH. Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes. Nature Chemistry. 3: 628-33. PMID 21778983 DOI: 10.1038/Nchem.1087  0.354
2008 Gunatilleke SS, de Oliveira CA, McCammon JA, Barrios AM. Inhibition of cathepsin B by Au(I) complexes: a kinetic and computational study. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 13: 555-61. PMID 18253767 DOI: 10.1007/S00775-008-0344-0  0.634
2008 Gunatilleke SS, Barrios AM. Tuning the Au(I)-mediated inhibition of cathepsin B through ligand substitutions. Journal of Inorganic Biochemistry. 102: 555-63. PMID 18164406 DOI: 10.1016/J.Jinorgbio.2007.10.019  0.616
2006 Gunatilleke SS, Barrios AM. Inhibition of lysosomal cysteine proteases by a series of Au(I) complexes: a detailed mechanistic investigation. Journal of Medicinal Chemistry. 49: 3933-7. PMID 16789749 DOI: 10.1021/Jm060158F  0.619
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