Sheila A. Lukehart - Publications

Affiliations: 
Global Health University of Washington, Seattle, Seattle, WA 
Area:
Molecular Biology, Microbiology Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Lin MJ, Haynes AM, Addetia A, Lieberman NAP, Phung Q, Xie H, Nguyen TV, Molini BJ, Lukehart SA, Giacani L, Greninger AL. Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune pressure. Plos Neglected Tropical Diseases. 15: e0009753. PMID 34492041 DOI: 10.1371/journal.pntd.0009753  0.377
2020 Baker BJ, Crane-Kramer G, Dee MW, Gregoricka LA, Henneberg M, Lee C, Lukehart SA, Mabey DC, Roberts CA, Stodder ALW, Stone AC, Winingear S. Advancing the understanding of treponemal disease in the past and present. American Journal of Physical Anthropology. PMID 31956996 DOI: 10.1002/Ajpa.23988  0.311
2019 Beale MA, Marks M, Sahi SK, Tantalo LC, Nori AV, French P, Lukehart SA, Marra CM, Thomson NR. Genomic epidemiology of syphilis reveals independent emergence of macrolide resistance across multiple circulating lineages. Nature Communications. 10: 3255. PMID 31332179 DOI: 10.1038/S41467-019-11216-7  0.304
2019 Molini B, Godornes C, Partida-Aguilar M, Haynes A, Gomez A, Carter D, Giacani L, Cameron C, Lukehart S. P763 Attenuation of syphilis infection following immunization of rabbits with a trivalent antigen cocktail Sexually Transmitted Infections. 95. DOI: 10.1136/Sextrans-2019-Sti.821  0.349
2019 Godornes C, Molini B, Giacani L, Gomez A, Carter D, Cameron C, Lukehart S. P754 Quantitation of cytokines in rabbits following tri-antigen vaccine cocktail immunization and T. pallidum challenge Sexually Transmitted Infections. 95. DOI: 10.1136/Sextrans-2019-Sti.812  0.356
2018 Chambers LC, Srinivasan S, Lukehart SA, Ocbamichael N, Morgan JL, Lowens MS, Fredricks DN, Golden MR, Manhart LE. Primary Syphilis in the Male Urethra - A Case Report. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30202933 DOI: 10.1093/Cid/Ciy771  0.321
2018 Lukehart SA. New Tools for Syphilis Research. Mbio. 9. PMID 30065094 DOI: 10.1128/Mbio.01417-18  0.331
2018 Esteves PJ, Abrantes J, Baldauf HM, BenMohamed L, Chen Y, Christensen N, González-Gallego J, Giacani L, Hu J, Kaplan G, Keppler OT, Knight KL, Kong XP, Lanning DK, Le Pendu J, ... ... Lukehart S, et al. The wide utility of rabbits as models of human diseases. Experimental & Molecular Medicine. 50: 66. PMID 29789565 DOI: 10.1038/S12276-018-0094-1  0.311
2017 Godornes C, Giacani L, Barry AE, Mitja O, Lukehart SA. Development of a Multilocus Sequence Typing (MLST) scheme for Treponema pallidum subsp. pertenue: Application to yaws in Lihir Island, Papua New Guinea. Plos Neglected Tropical Diseases. 11: e0006113. PMID 29281641 DOI: 10.1371/Journal.Pntd.0006113  0.342
2017 Marks M, Fookes M, Wagner J, Butcher R, Ghinai R, Sokana O, Sarkodie YA, Lukehart SA, Solomon AW, Mabey DCW, Thomson N. Diagnostics for yaws eradication: insights from direct next generation sequencing of cutaneous strains of Treponema pallidum. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 29045605 DOI: 10.1093/Cid/Cix892  0.365
2017 Klegarth AR, Ezeonwu CA, Rompis A, Lee BPY, Aggimarangsee N, Chalise M, Cortes J, Feeroz M, Molini BJ, Godornes BC, Marks M, Schillaci M, Engel G, Knauf S, Lukehart SA, et al. Survey of Treponemal Infections in Free-Ranging and Captive Macaques, 1999-2012. Emerging Infectious Diseases. 23: 816-819. PMID 28418297 DOI: 10.3201/Eid2305.161838  0.323
2016 Molini BJ, Tantalo LC, Sahi SK, Rodriguez VI, Brandt SL, Fernandez MC, Godornes CB, Marra CM, Lukehart SA. Macrolide Resistance in Treponema pallidum Correlates With 23S rDNA Mutations in Recently Isolated Clinical Strains. Sexually Transmitted Diseases. 43: 579-83. PMID 27513385 DOI: 10.1097/Olq.0000000000000486  0.314
2016 Marra CM, Tantalo LC, Sahi SK, Dunaway SB, Lukehart SA. Reduced Treponema pallidum-Specific Opsonic Antibody Activity in HIV-Infected Patients With Syphilis. The Journal of Infectious Diseases. 213: 1348-54. PMID 26655298 DOI: 10.1093/Infdis/Jiv591  0.324
2015 Giacani L, Brandt SL, Ke W, Reid TB, Molini BJ, Iverson-Cabral S, Ciccarese G, Drago F, Lukehart SA, Centurion-Lara A. Transcription of TP0126, Treponema pallidum putative OmpW homolog, is regulated by the length of a homopolymeric guanosine repeat. Infection and Immunity. 83: 2275-89. PMID 25802057 DOI: 10.1128/Iai.00360-15  0.772
2015 Ke W, Molini BJ, Lukehart SA, Giacani L. Treponema pallidum subsp. pallidum TP0136 protein is heterogeneous among isolates and binds cellular and plasma fibronectin via its NH2-terminal end. Plos Neglected Tropical Diseases. 9: e0003662. PMID 25793702 DOI: 10.1371/Journal.Pntd.0003662  0.387
2014 Reid TB, Molini BJ, Fernandez MC, Lukehart SA. Antigenic variation of TprK facilitates development of secondary syphilis. Infection and Immunity. 82: 4959-67. PMID 25225245 DOI: 10.1128/Iai.02236-14  0.777
2014 Lukehart SA, Giacani L. When is syphilis not syphilis? Or is it? Sexually Transmitted Diseases. 41: 554-5. PMID 25118970 DOI: 10.1097/Olq.0000000000000179  0.362
2014 Mitjà O, Lukehart SA, Pokowas G, Moses P, Kapa A, Godornes C, Robson J, Cherian S, Houinei W, Kazadi W, Siba P, de Lazzari E, Bassat Q. Haemophilus ducreyi as a cause of skin ulcers in children from a yaws-endemic area of Papua New Guinea: a prospective cohort study. The Lancet. Global Health. 2: e235-41. PMID 25103064 DOI: 10.1016/S2214-109X(14)70019-1  0.319
2014 Giacani L, Iverson-Cabral SL, King JC, Molini BJ, Lukehart SA, Centurion-Lara A. Complete Genome Sequence of the Treponema pallidum subsp. pallidum Sea81-4 Strain. Genome Announcements. 2. PMID 24744342 DOI: 10.1128/Genomea.00333-14  0.32
2014 Giacani L, Lukehart SA. The endemic treponematoses. Clinical Microbiology Reviews. 27: 89-115. PMID 24396138 DOI: 10.1128/Cmr.00070-13  0.372
2014 Cameron CE, Lukehart SA. Current status of syphilis vaccine development: need, challenges, prospects. Vaccine. 32: 1602-9. PMID 24135571 DOI: 10.1016/J.Vaccine.2013.09.053  0.307
2013 Centurion-Lara A, Giacani L, Godornes C, Molini BJ, Brinck Reid T, Lukehart SA. Fine analysis of genetic diversity of the tpr gene family among treponemal species, subspecies and strains. Plos Neglected Tropical Diseases. 7: e2222. PMID 23696912 DOI: 10.1371/Journal.Pntd.0002222  0.413
2013 Lukehart SA. PL03.3 Syphilis: From Pathogenesis to Control Sexually Transmitted Infections. 89: A3.3-A4. DOI: 10.1136/Sextrans-2013-051184.0008  0.41
2012 Grimes M, Sahi SK, Godornes BC, Tantalo LC, Roberts N, Bostick D, Marra CM, Lukehart SA. Two mutations associated with macrolide resistance in Treponema pallidum: increasing prevalence and correlation with molecular strain type in Seattle, Washington. Sexually Transmitted Diseases. 39: 954-8. PMID 23191949 DOI: 10.1097/Olq.0B013E31826Ae7A8  0.313
2012 Giacani L, Chattopadhyay S, Centurion-Lara A, Jeffrey BM, Le HT, Molini BJ, Lukehart SA, Sokurenko EV, Rockey DD. Footprint of positive selection in Treponema pallidum subsp. pallidum genome sequences suggests adaptive microevolution of the syphilis pathogen. Plos Neglected Tropical Diseases. 6: e1698. PMID 22720110 DOI: 10.1371/Journal.Pntd.0001698  0.381
2012 Giacani L, Brandt SL, Puray-Chavez M, Reid TB, Godornes C, Molini BJ, Benzler M, Hartig JS, Lukehart SA, Centurion-Lara A. Comparative investigation of the genomic regions involved in antigenic variation of the TprK antigen among treponemal species, subspecies, and strains. Journal of Bacteriology. 194: 4208-25. PMID 22661689 DOI: 10.1128/Jb.00863-12  0.797
2011 Ho EL, Lukehart SA. Syphilis: using modern approaches to understand an old disease. The Journal of Clinical Investigation. 121: 4584-92. PMID 22133883 DOI: 10.1172/Jci57173  0.301
2010 Marra C, Sahi S, Tantalo L, Godornes C, Reid T, Behets F, Rompalo A, Klausner JD, Yin Y, Mulcahy F, Golden MR, Centurion-Lara A, Lukehart SA. Enhanced molecular typing of treponema pallidum: geographical distribution of strain types and association with neurosyphilis. The Journal of Infectious Diseases. 202: 1380-8. PMID 20868271 DOI: 10.1086/656533  0.754
2010 Giacani L, Jeffrey BM, Molini BJ, Le HT, Lukehart SA, Centurion-Lara A, Rockey DD. Complete genome sequence and annotation of the Treponema pallidum subsp. pallidum Chicago strain. Journal of Bacteriology. 192: 2645-6. PMID 20348263 DOI: 10.1128/Jb.00159-10  0.345
2010 Giacani L, Molini BJ, Kim EY, Godornes BC, Leader BT, Tantalo LC, Centurion-Lara A, Lukehart SA. Antigenic variation in Treponema pallidum: TprK sequence diversity accumulates in response to immune pressure during experimental syphilis. Journal of Immunology (Baltimore, Md. : 1950). 184: 3822-9. PMID 20190145 DOI: 10.4049/Jimmunol.0902788  0.763
2009 Palmer GH, Bankhead T, Lukehart SA. 'Nothing is permanent but change'- antigenic variation in persistent bacterial pathogens. Cellular Microbiology. 11: 1697-705. PMID 19709057 DOI: 10.1111/J.1462-5822.2009.01366.X  0.433
2009 Deitsch KW, Lukehart SA, Stringer JR. Common strategies for antigenic variation by bacterial, fungal and protozoan pathogens. Nature Reviews. Microbiology. 7: 493-503. PMID 19503065 DOI: 10.1038/Nrmicro2145  0.363
2009 Giacani L, Godornes C, Puray-Chavez M, Guerra-Giraldez C, Tompa M, Lukehart SA, Centurion-Lara A. TP0262 is a modulator of promoter activity of tpr Subfamily II genes of Treponema pallidum ssp. pallidum. Molecular Microbiology. 72: 1087-99. PMID 19432808 DOI: 10.1111/J.1365-2958.2009.06712.X  0.346
2008 Brissette CA, Pham TT, Coats SR, Darveau RP, Lukehart SA. Treponema denticola does not induce production of common innate immune mediators from primary gingival epithelial cells. Oral Microbiology and Immunology. 23: 474-81. PMID 18954353 DOI: 10.1111/J.1399-302X.2008.00452.X  0.656
2007 Lukehart SA, Marra CM. Isolation and laboratory maintenance of Treponema pallidum. Current Protocols in Microbiology. Unit 12A.1. PMID 18770607 DOI: 10.1002/9780471729259.Mc12A01S7  0.328
2007 Godornes C, Leader BT, Molini BJ, Centurion-Lara A, Lukehart SA. Quantitation of rabbit cytokine mRNA by real-time RT-PCR. Cytokine. 38: 1-7. PMID 17521914 DOI: 10.1016/J.Cyto.2007.04.002  0.727
2007 Leader BT, Godornes C, VanVoorhis WC, Lukehart SA. CD4+ lymphocytes and gamma interferon predominate in local immune responses in early experimental syphilis. Infection and Immunity. 75: 3021-6. PMID 17403876 DOI: 10.1128/Iai.01973-06  0.754
2007 Brissette CA, Lukehart SA. Mechanisms of decreased susceptibility to beta-defensins by Treponema denticola. Infection and Immunity. 75: 2307-15. PMID 17325047 DOI: 10.1128/Iai.01718-06  0.662
2007 Giacani L, Molini B, Godornes C, Barrett L, Van Voorhis W, Centurion-Lara A, Lukehart SA. Quantitative analysis of tpr gene expression in Treponema pallidum isolates: Differences among isolates and correlation with T-cell responsiveness in experimental syphilis. Infection and Immunity. 75: 104-12. PMID 17030565 DOI: 10.1128/Iai.01124-06  0.434
2006 Marra CM, Colina AP, Godornes C, Tantalo LC, Puray M, Centurion-Lara A, Lukehart SA. Antibiotic selection may contribute to increases in macrolide-resistant Treponema pallidum. The Journal of Infectious Diseases. 194: 1771-3. PMID 17109351 DOI: 10.1086/509512  0.306
2006 Centurion-Lara A, Molini BJ, Godornes C, Sun E, Hevner K, Van Voorhis WC, Lukehart SA. Molecular differentiation of Treponema pallidum subspecies. Journal of Clinical Microbiology. 44: 3377-80. PMID 16954278 DOI: 10.1128/Jcm.00784-06  0.355
2006 Gray RR, Mulligan CJ, Molini BJ, Sun ES, Giacani L, Godornes C, Kitchen A, Lukehart SA, Centurion-Lara A. Molecular evolution of the tprC, D, I, K, G, and J genes in the pathogenic genus Treponema. Molecular Biology and Evolution. 23: 2220-33. PMID 16926243 DOI: 10.1093/Molbev/Msl092  0.346
2006 LaFond RE, Molini BJ, Van Voorhis WC, Lukehart SA. Antigenic variation of TprK V regions abrogates specific antibody binding in syphilis. Infection and Immunity. 74: 6244-51. PMID 16923793 DOI: 10.1128/Iai.00827-06  0.768
2006 Leader BT, VanVoorhis WC, Lukehart SA. Expression of rabbit interleukin-4 and characterization of its biologic activity on T and B-cells. Veterinary Immunology and Immunopathology. 113: 421-7. PMID 16879875 DOI: 10.1016/J.Vetimm.2006.06.001  0.739
2006 LaFond RE, Centurion-Lara A, Godornes C, Van Voorhis WC, Lukehart SA. TprK sequence diversity accumulates during infection of rabbits with Treponema pallidum subsp. pallidum Nichols strain. Infection and Immunity. 74: 1896-906. PMID 16495565 DOI: 10.1128/Iai.74.3.1896-1906.2006  0.768
2006 Lafond RE, Lukehart SA. Biological basis for syphilis. Clinical Microbiology Reviews. 19: 29-49. PMID 16418521 DOI: 10.1128/Cmr.19.1.29-49.2006  0.764
2005 Tantalo LC, Lukehart SA, Marra CM. Treponema pallidum strain-specific differences in neuroinvasion and clinical phenotype in a rabbit model. The Journal of Infectious Diseases. 191: 75-80. PMID 15593006 DOI: 10.1086/426510  0.352
2004 Giacani L, Sun ES, Hevner K, Molini BJ, Van Voorhis WC, Lukehart SA, Centurion-Lara A. Tpr homologs in Treponema paraluiscuniculi Cuniculi A strain. Infection and Immunity. 72: 6561-76. PMID 15501788 DOI: 10.1128/Iai.72.11.6561-6576.2004  0.479
2004 Brissette CA, Simonson LG, Lukehart SA. Resistance to human beta-defensins is common among oral treponemes. Oral Microbiology and Immunology. 19: 403-7. PMID 15491467 DOI: 10.1111/J.1399-302X.2004.00177.X  0.662
2004 Lukehart SA, Godornes C, Molini BJ, Sonnett P, Hopkins S, Mulcahy F, Engelman J, Mitchell SJ, Rompalo AM, Marra CM, Klausner JD. Macrolide resistance in Treponema pallidum in the United States and Ireland. The New England Journal of Medicine. 351: 154-8. PMID 15247355 DOI: 10.1056/Nejmoa040216  0.308
2004 Sun ES, Molini BJ, Barrett LK, Centurion-Lara A, Lukehart SA, Van Voorhis WC. Subfamily I Treponema pallidum repeat protein family: sequence variation and immunity. Microbes and Infection / Institut Pasteur. 6: 725-37. PMID 15207819 DOI: 10.1016/J.Micinf.2004.04.001  0.453
2004 Centurion-Lara A, LaFond RE, Hevner K, Godornes C, Molini BJ, Van Voorhis WC, Lukehart SA. Gene conversion: a mechanism for generation of heterogeneity in the tprK gene of Treponema pallidum during infection. Molecular Microbiology. 52: 1579-96. PMID 15186410 DOI: 10.1111/J.1365-2958.2004.04086.X  0.758
2003 LaFond RE, Centurion-Lara A, Godornes C, Rompalo AM, Van Voorhis WC, Lukehart SA. Sequence diversity of Treponema pallidum subsp. pallidum tprK in human syphilis lesions and rabbit-propagated isolates. Journal of Bacteriology. 185: 6262-8. PMID 14563860 DOI: 10.1128/Jb.185.21.6262-6268.2003  0.753
2003 Leader BT, Hevner K, Molini BJ, Barrett LK, Van Voorhis WC, Lukehart SA. Antibody responses elicited against the Treponema pallidum repeat proteins differ during infection with different isolates of Treponema pallidum subsp. pallidum. Infection and Immunity. 71: 6054-7. PMID 14500529 DOI: 10.1128/Iai.71.10.6054-6057.2003  0.764
2003 Morgan CA, Lukehart SA, Van Voorhis WC. Protection against syphilis correlates with specificity of antibodies to the variable regions of Treponema pallidum repeat protein K. Infection and Immunity. 71: 5605-12. PMID 14500480 DOI: 10.1128/Iai.71.10.5605-5612.2003  0.404
2003 Van Voorhis WC, Barrett LK, Lukehart SA, Schmidt B, Schriefer M, Cameron CE. Serodiagnosis of syphilis: antibodies to recombinant Tp0453, Tp92, and Gpd proteins are sensitive and specific indicators of infection by Treponema pallidum. Journal of Clinical Microbiology. 41: 3668-74. PMID 12904373 DOI: 10.1128/Jcm.41.8.3668-3674.2003  0.364
2002 Morgan CA, Lukehart SA, Van Voorhis WC. Immunization with the N-terminal portion of Treponema pallidum repeat protein K attenuates syphilitic lesion development in the rabbit model. Infection and Immunity. 70: 6811-6. PMID 12438357 DOI: 10.1128/Iai.70.12.6811-6816.2002  0.416
2002 Morgan CA, Molini BJ, Lukehart SA, Van Voorhis WC. Segregation of B and T cell epitopes of Treponema pallidum repeat protein K to variable and conserved regions during experimental syphilis infection. Journal of Immunology (Baltimore, Md. : 1950). 169: 952-7. PMID 12097401 DOI: 10.4049/Jimmunol.169.2.952  0.444
2002 Brissette CA, Lukehart SA. Treponema denticola is resistant to human beta-defensins. Infection and Immunity. 70: 3982-4. PMID 12065549 DOI: 10.1128/Iai.70.7.3982-3984.2002  0.632
2002 Antal GM, Lukehart SA, Meheus AZ. The endemic treponematoses. Microbes and Infection / Institut Pasteur. 4: 83-94. PMID 11825779 DOI: 10.1016/S1286-4579(01)01513-1  0.354
2000 Cameron CE, Lukehart SA, Castro C, Molini B, Godornes C, Van Voorhis WC. Opsonic potential, protective capacity, and sequence conservation of the Treponema pallidum subspecies pallidum Tp92 Journal of Infectious Diseases. 181: 1401-1413. PMID 10762571 DOI: 10.1086/315399  0.41
2000 Centurion-Lara A, Sun ES, Barrett LK, Castro C, Lukehart SA, Van Voorhis WC. Multiple alleles of Treponema pallidum repeat gene D in Treponema pallidum isolates. Journal of Bacteriology. 182: 2332-5. PMID 10735882 DOI: 10.1128/Jb.182.8.2332-2335.2000  0.406
2000 Centurion-Lara A, Godornes C, Castro C, Van Voorhis WC, Lukehart SA. The tprK gene is heterogeneous among Treponema pallidum strains and has multiple alleles Infection and Immunity. 68: 824-831. PMID 10639452 DOI: 10.1128/Iai.68.2.824-831.2000  0.437
1999 Kolman CJ, Centurion-Lara A, Lukehart SA, Owsley DW, Tuross NC. Identification of Treponema pallidum subspecies pallidum in a 200-year- old skeletal specimen Journal of Infectious Diseases. 180: 2060-2063. PMID 10558971 DOI: 10.1086/315151  0.359
1999 Arroll TW, Centurion-Lara A, Lukehart SA, Van Voorhis WC. T-cell responses to Treponema pallidum subsp, pallidum antigens during the course of experimental syphilis infection Infection and Immunity. 67: 4757-4763. PMID 10456928 DOI: 10.1128/Iai.67.9.4757-4763.1999  0.439
1999 Cameron CE, Castro C, Lukehart SA, Van Voorhis WC. Sequence conservation of glycerophosphodiester phosphodiesterase among Treponema pallidum strains Infection and Immunity. 67: 3168-3170. PMID 10338539 DOI: 10.1128/Iai.67.6.3168-3170.1999  0.43
1999 Houston LS, Lukehart SA, Persson GR, Page RC. Function of anti-Porphyromonas gingivalis immunoglobulin classes in immunized Macaca fascicularis. Oral Microbiology and Immunology. 14: 86-91. PMID 10219166 DOI: 10.1034/J.1399-302X.1999.140202.X  0.32
1999 Centurion-Lara A, Castro C, Barrett L, Cameron C, Mostowfi M, Van Voorhis WC, Lukehart SA. Treponema pallidum major sheath protein homologue Tpr K is a target of opsonic antibody and the protective immune response Journal of Experimental Medicine. 189: 647-656. PMID 9989979 DOI: 10.1084/Jem.189.4.647  0.423
1998 Cameron CE, Castro C, Lukehart SA, Van Voorhis WC. Function and protective capacity of Treponema pallidum subsp. pallidum Glycerophosphodiester phosphodiesterase Infection and Immunity. 66: 5763-5770. PMID 9826352 DOI: 10.1128/Iai.66.12.5763-5770.1998  0.435
1998 Centurion-Lara A, Castro C, Castillo R, Shaffer JM, Van Voorhis WC, Lukehart SA. The flanking region sequences of the 15-kDa lipoprotein gene differentiate pathogenic treponemes Journal of Infectious Diseases. 177: 1036-1040. PMID 9534979 DOI: 10.1086/515247  0.412
1997 Stebeck CE, Shaffer JM, Arroll TW, Lukehart SA, Van Voorhis WC. Identification of the Treponema pallidum subsp. Pallidum glycerophosphodiester phosphodiesterase bomologue Fems Microbiology Letters. 154: 303-310. PMID 9311129 DOI: 10.1111/J.1574-6968.1997.Tb12660.X  0.35
1997 Centurion-Lara A, Castro C, Shaffer JM, Van Voorhis WC, Marra CM, Lukehart SA. Detection of Treponema pallidum by a sensitive reverse transcriptase PCR Journal of Clinical Microbiology. 35: 1348-1352. PMID 9163442 DOI: 10.1128/Jcm.35.6.1348-1352.1997  0.351
1997 Centurion-Lara A, Arroll T, Castillo R, Shaffer JM, Castro C, Van Voorhis WC, Lukehart SA. Conservation of the 15-kilodalton lipoprotein among Treponema pallidum subspecies and strains and other pathogenic treponemes: Genetic and antigenic analyses Infection and Immunity. 65: 1440-1444. PMID 9119485 DOI: 10.1128/Iai.65.4.1440-1444.1997  0.485
1996 Cummings MC, Lukehart SA, Marra C, Smith BL, Shaffer J, Demeo LR, Castro C, Mccormack WM. Comparison of methods for the detection of Treponema pallidum in lesions of early Syphilis Sexually Transmitted Diseases. 23: 366-369. PMID 8885066 DOI: 10.1097/00007435-199609000-00004  0.326
1996 Van Voorhis WC, Barrett LK, Nasio JM, Plummer FA, Lukehart SA. Lesions of primary and secondary syphilis contain activated cytolytic T cells Infection and Immunity. 64: 1048-1050. PMID 8641758 DOI: 10.1128/Iai.64.3.1048-1050.1996  0.303
1994 Gordon SM, Eaton ME, George R, Larsen S, Lukehart SA, Kuypers J, Marra CM, Thompson S. The response of symptomatic neurosyphilis to high-dose intravenous penicillin G in patients with human immunodeficiency virus infection New England Journal of Medicine. 331: 1469-1473. PMID 7969296 DOI: 10.1056/Nejm199412013312201  0.311
1993 Baker-Zander SA, Shaffer JM, Lukehart SA. Characterization of the serum requirement for macrophage-mediated killing of Treponema pallidum ssp. pallidum: Relationship to the development of opsonizing antibodies Fems Immunology and Medical Microbiology. 6: 273-279. PMID 8499892 DOI: 10.1111/J.1574-695X.1993.Tb00339.X  0.395
1993 Baker-Zander SA, Shaffer JM, Lukehart SA. VDRL Antibodies Enhance Phagocytosis of Treponema pallidum by Macrophages Journal of Infectious Diseases. 167: 1100-1105. PMID 8486943 DOI: 10.1093/Infdis/167.5.1100  0.369
1993 Shaffer JM, Baker-Zander SA, Lukehart SA. Opsonization of Treponema pallidum is mediated by immunoglobulin G antibodies induced only by pathogenic treponemes Infection and Immunity. 61: 781-784. PMID 8423106 DOI: 10.1128/Iai.61.2.781-784.1993  0.336
1993 Moncó JCG, Wheeler CM, Benach JL, Furie RA, Lukehart SA, Stanek G, Steere AC. Reactivity of neuroborreliosis patients (Lyme disease) to cardiolipin and gangliosides Journal of the Neurological Sciences. 117: 206-214. PMID 8410057 DOI: 10.1016/0022-510X(93)90175-X  0.304
1992 Marra CM, Hunter Handsfield H, La Kuller R, Morton WR, Lukehart SA. Alterations in the course of experimental syphilis associated with concurrent simian immunodeficiency virus infection Journal of Infectious Diseases. 165: 1020-1025. PMID 1583318 DOI: 10.1093/Infdis/165.6.1020  0.435
1992 Lukehart SA, Shaffer JM, Baker-Zander SA. A subpopulation of treponema pallidum is resistant to phagocytosis: Possible mechanism of persistence Journal of Infectious Diseases. 166: 1449-1453. PMID 1431264 DOI: 10.1093/Infdis/166.6.1449  0.389
1992 Riviere GR, Elliot KS, Adams DF, Simonson LG, Forgas LB, Nilius AM, Lukehart SA. Relative proportions of pathogen-related oral spirochetes (PROS) and Treponema denticola in supragingival and subgingival plaque from patients with periodontitis Journal of Periodontology. 63: 131-136. PMID 1372653 DOI: 10.1902/Jop.1992.63.2.131  0.358
1991 Marra C, Baker-Zander SA, Hook EW, Lukehart SA. An experimental model of early central nervous system syphilis Journal of Infectious Diseases. 163: 825-829. PMID 2010635 DOI: 10.1093/Infdis/163.4.825  0.354
1991 Burstain JM, Grimprel E, Lukehart SA, Norgard MV, Radolf JD. Sensitive detection of Treponema pallidum by using the polymerase chain reaction Journal of Clinical Microbiology. 29: 62-69. PMID 1993770 DOI: 10.1128/Jcm.29.1.62-69.1991  0.311
1991 Barron SL, Riviere GR, Simonson LG, Lukehart SA, Tira DE, O'Neil DW. Use of monoclonal antibodies to enumerate spirochetes and identify Treponema denticola in dental plaque of children, adolescents and young adults Oral Microbiology and Immunology. 6: 97-101. PMID 1945493 DOI: 10.1111/J.1399-302X.1991.Tb00458.X  0.336
1991 Schwebke JR, Lukehart SA, Roberts MC, Hillier SL. Identification of two new antigenic subgroups within the genus Mobiluncus Journal of Clinical Microbiology. 29: 2204-2208. PMID 1939572 DOI: 10.1128/Jcm.29.10.2204-2208.1991  0.334
1991 Riviere GR, Weisz KS, Simonson LG, Lukehart SA. Pathogen-related spirochetes identified within gingival tissue from patients with acute necrotizing ulcerative gingivitis Infection and Immunity. 59: 2653-2657. PMID 1855985 DOI: 10.1128/Iai.59.8.2653-2657.1991  0.337
1991 Riviere GR, Wagoner MA, Baker-Zander SA, Weisz KS, Adams DF, Simonson L, Lukehart SA. Identification of spirochetes related to Treponema Pallidum in necrotizing ulcerative gingivitis and chronic periodontitis New England Journal of Medicine. 325: 539-543. PMID 1713299 DOI: 10.1056/Nejm199108223250803  0.339
1990 Schwebke JR, Hillier SL, Fohn MJ, Lukehart SA. Demonstration of heterogeneity among the antigenic proteins of Mobiluncus species Journal of Clinical Microbiology. 28: 463-468. PMID 1691207 DOI: 10.1128/Jcm.28.3.463-468.1990  0.352
1989 Isaacs RD, Hanke JH, Guzman-Verduzco LM, Newport G, Agabian N, Norgard MV, Lukehart SA, Radolf JD. Molecular cloning and DNA sequence analysis of the 37-kilodalton endoflagellar sheath protein gene of Treponema pallidum. Infection and Immunity. 57: 3403-11. PMID 2680972 DOI: 10.1128/Iai.57.11.3403-3411.1989  0.312
1988 Fohn MJ, Wignall FS, Baker-Zander SA, Lukehart SA. Specificity of antibodies from patients with pinta for antigens of lyeponema pallidum subspecies pallidum Journal of Infectious Diseases. 157: 32-37. PMID 3275725 DOI: 10.1093/Infdis/157.1.32  0.403
1988 Lukehart SA, Hook EW, Baker-Zander SA, Collier AC, Critchlow CW, Handsfield HH. Invasion of the central nervous system by Treponema pallidum: Implications for diagnosis and treatment Annals of Internal Medicine. 109: 855-862. PMID 3056164 DOI: 10.7326/0003-4819-109-11-855  0.349
1987 Torian BE, Lukehart SA, Stamm WE. Use of Monoclonal Antibodies to Identify, Characterize, and Purify a 96,000-Dalton Surface Antigen of Pathogenic Entamoeba Histolytica Journal of Infectious Diseases. 156: 334-343. PMID 2885384 DOI: 10.1093/Infdis/156.2.334  0.331
1985 Hook EW, Roddy RE, Lukehart SA, Hom J, Holmes KK, Tam MR. Detection of Treponema pallidum in lesion exudate with a pathogen-specific monoclonal antibody. Journal of Clinical Microbiology. 22: 241-4. PMID 3897267 DOI: 10.1128/Jcm.22.2.241-244.1985  0.344
1985 Lukehart SA. Prospects for development of a treponemal vaccine Clinical Infectious Diseases. 7: S305-S313. PMID 3892634 DOI: 10.1093/Clinids/7-Supplement_2.S305  0.332
1985 DiGiacomo RF, Lukehart SA, Talburt CD, Baker-Zander SA, Giddens WE, Condon J, Brown CW. Chronicity of infection with Treponema paraluis-cuniculi in New Zealand white rabbits. Genitourinary Medicine. 61: 156-64. PMID 3891583 DOI: 10.1136/Sti.61.3.156  0.33
1985 Baker-Zander SA, Hook EW, Bonin P, Handsfield HH, Lukehart SA. Antigens of treponema pallidum recognized by igg and igm antibodies during syphilis in humans Journal of Infectious Diseases. 151: 264-272. PMID 3881539 DOI: 10.1093/Infdis/151.2.264  0.339
1985 Lukehart SA, Tam MR, Hom J, Baker-Zander SA, Holmes KK, Nowinski RC. Characterization of monoclonal antibodies to Treponema pallidum. Journal of Immunology (Baltimore, Md. : 1950). 134: 585-92. PMID 3880576  0.306
1984 Baker-Zander SA, Lukehart SA. Antigenic cross-reactivity between Treponema pallidum and other pathogenic members of the family Spirochaetaceae Infection and Immunity. 46: 116-121. PMID 6384040 DOI: 10.1128/Iai.46.1.116-121.1984  0.421
1982 Baker-Zander SA, Sell S, Lukehart SA. Serum regulation of in vitro lymphocyte responses in early experimental syphilis Infection and Immunity. 37: 568-578. PMID 6749683 DOI: 10.1128/Iai.37.2.568-578.1982  0.391
1981 Lukehart SA, Baker-Zander SA, Cheri Lloyd RM, Sell S. Effect of cortisone administration on host-parasite relationships in early experimental syphilis Journal of Immunology. 127: 1361-1368. PMID 7024407  0.313
1980 Sell S, Gamboa D, Baker-Zander SA, Lukehart SA, Miller JN. Host response to Treponema pallidum in intradermally-infected rabbits: Evidence for persistence of infection at local and distant sites Journal of Investigative Dermatology. 75: 470-475. PMID 7003026 DOI: 10.1111/1523-1747.Ep12524230  0.386
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