| Year |
Citation |
Score |
| 2020 |
Frank MW, Yao J, Batte JL, Gullett JM, Subramanian C, Rosch JW, Rock CO. Host Fatty Acid Utilization by Staphylococcus aureus at the Infection Site. Mbio. 11. PMID 32430471 DOI: 10.1128/Mbio.00920-20 |
0.351 |
|
| 2020 |
Radka CD, Frank MW, Yao J, Seetharaman J, Miller DJ, Rock CO. The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI). The Journal of Biological Chemistry. PMID 32317282 DOI: 10.1074/Jbc.Ra120.013336 |
0.368 |
|
| 2020 |
Subramanian C, Yao J, Frank MW, Rock CO, Jackowski S. A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165663. PMID 31918006 DOI: 10.1016/J.Bbadis.2020.165663 |
0.307 |
|
| 2019 |
Wallace MJ, Dharuman S, Fernando D, Reeve SM, Gee C, Yao J, Griffith E, Phelps G, Wright WC, Elmore J, Lee RB, Chen T, Lee RE. Discovery and characterization of the antimetabolite action of thioacetamide-linked 1,2,3-triazoles as disruptors of cysteine biosynthesis in Gram-negative bacteria. Acs Infectious Diseases. PMID 31887254 DOI: 10.1021/Acsinfecdis.9B00406 |
0.392 |
|
| 2019 |
Radka CD, Frank MW, Rock CO, Yao J. Fatty acid activation and utilization by Alistipes finegoldii, a representative Bacteroidetes resident of the human gut microbiome. Molecular Microbiology. PMID 31876062 DOI: 10.1111/Mmi.14445 |
0.33 |
|
| 2019 |
Párraga Solórzano PK, Yao J, Rock CO, Kehl-Fie TE. Disruption of Glycolysis by Nutritional Immunity Activates a Two-Component System That Coordinates a Metabolic and Antihost Response by Staphylococcus aureus. Mbio. 10. PMID 31387906 DOI: 10.1128/Mbio.01321-19 |
0.324 |
|
| 2019 |
Yao J, Subramanian C, Rock CO, Jackowski S. Human Pantothenate Kinase 4 (PANK4) is a Pseudo-Pantothenate Kinase. Protein Science : a Publication of the Protein Society. PMID 30927326 DOI: 10.1002/Pro.3611 |
0.317 |
|
| 2018 |
Yao J, Rock CO. Therapeutic Targets in Chlamydial Fatty Acid and Phospholipid Synthesis. Frontiers in Microbiology. 9: 2291. PMID 30319589 DOI: 10.3389/Fmicb.2018.02291 |
0.353 |
|
| 2017 |
Robertson RM, Yao J, Gajewski S, Kumar G, Martin EW, Rock CO, White SW. A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer. Nature Structural & Molecular Biology. PMID 28714993 DOI: 10.1038/Nsmb.3436 |
0.383 |
|
| 2017 |
Yao J, Rock CO. Exogenous fatty acid metabolism in bacteria. Biochimie. PMID 28668270 DOI: 10.1016/J.Biochi.2017.06.015 |
0.377 |
|
| 2016 |
Yao J, Ericson ME, Frank MW, Rock CO. Enoyl-Acyl Carrier Protein Reductase I (FabI) is Essential for the Intracellular Growth of Listeria monocytogenes. Infection and Immunity. PMID 27736774 DOI: 10.1128/Iai.00647-16 |
0.405 |
|
| 2016 |
Yao J, Rock CO. Bacterial fatty acid metabolism in modern antibiotic discovery. Biochimica Et Biophysica Acta. PMID 27668701 DOI: 10.1016/J.Bbalip.2016.09.014 |
0.375 |
|
| 2016 |
Subramanian C, Yun MK, Yao J, Sharma LK, Lee RE, White SW, Jackowski S, Rock CO. Allosteric Regulation of Mammalian Pantothenate Kinase. The Journal of Biological Chemistry. PMID 27555321 DOI: 10.1074/Jbc.M116.748061 |
0.417 |
|
| 2016 |
Yao J, Carter RA, Vuagniaux G, Barbier M, Rosch JW, Rock CO. A Pathogen-Selective Antibiotic Minimizes Disturbance to the Microbiome. Antimicrobial Agents and Chemotherapy. PMID 27161626 DOI: 10.1128/Aac.00535-16 |
0.302 |
|
| 2016 |
Yao J, Rock CO. Resistance Mechanisms and the Future of Bacterial Enoyl-Acyl Carrier Protein Reductase (FabI) Antibiotics. Cold Spring Harbor Perspectives in Medicine. 6. PMID 26931811 DOI: 10.1101/Cshperspect.A027045 |
0.322 |
|
| 2015 |
Yao J, Bruhn DF, Frank MW, Lee RE, Rock CO. Activation of exogenous fatty acids to acyl-acyl carrier protein cannot bypass FabI inhibition in Neisseria. The Journal of Biological Chemistry. PMID 26567338 DOI: 10.1074/Jbc.M115.699462 |
0.342 |
|
| 2015 |
Yao J, Dodson VJ, Frank MW, Rock CO. Chlamydia trachomatis Scavenges Host Fatty Acids for Phospholipid Synthesis via an Acyl-Acyl Carrier Protein Synthetase. The Journal of Biological Chemistry. 290: 22163-73. PMID 26195634 DOI: 10.1074/Jbc.M115.671008 |
0.359 |
|
| 2015 |
Yao J, Cherian PT, Frank MW, Rock CO. Chlamydia trachomatis Relies on Autonomous Phospholipid Synthesis for Membrane Biogenesis. The Journal of Biological Chemistry. PMID 25995447 DOI: 10.1074/Jbc.M115.657148 |
0.337 |
|
| 2015 |
Yao J, Rock CO. How bacterial pathogens eat host lipids: implications for the development of fatty acid synthesis therapeutics. The Journal of Biological Chemistry. 290: 5940-6. PMID 25648887 DOI: 10.1074/Jbc.R114.636241 |
0.342 |
|
| 2015 |
Parsons JB, Yao J, Frank MW, Rock CO. FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 59: 849-58. PMID 25403676 DOI: 10.1128/Aac.04179-14 |
0.353 |
|
| 2014 |
Yao J, Abdelrahman YM, Robertson RM, Cox JV, Belland RJ, White SW, Rock CO. Type II fatty acid synthesis is essential for the replication of Chlamydia trachomatis. The Journal of Biological Chemistry. 289: 22365-76. PMID 24958721 DOI: 10.1074/Jbc.M114.584185 |
0.386 |
|
| 2013 |
Parsons JB, Yao J, Jackson P, Frank M, Rock CO. Phosphatidylglycerol homeostasis in glycerol-phosphate auxotrophs of Staphylococcus aureus. Bmc Microbiology. 13: 260. PMID 24238430 DOI: 10.1186/1471-2180-13-260 |
0.375 |
|
| 2013 |
Yao J, Maxwell JB, Rock CO. Resistance to AFN-1252 arises from missense mutations in Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI). The Journal of Biological Chemistry. 288: 36261-71. PMID 24189061 DOI: 10.1074/Jbc.M113.512905 |
0.316 |
|
| 2013 |
Yao J, Rock CO. Phosphatidic acid synthesis in bacteria. Biochimica Et Biophysica Acta. 1831: 495-502. PMID 22981714 DOI: 10.1016/J.Bbalip.2012.08.018 |
0.436 |
|
| 2012 |
Parsons JB, Yao J, Frank MW, Jackson P, Rock CO. Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus. Journal of Bacteriology. 194: 5294-304. PMID 22843840 DOI: 10.1128/Jb.00743-12 |
0.372 |
|
| 2012 |
Cherian PT, Yao J, Leonardi R, Maddox MM, Luna VA, Rock CO, Lee RE. Acyl-sulfamates target the essential glycerol-phosphate acyltransferase (PlsY) in Gram-positive bacteria. Bioorganic & Medicinal Chemistry. 20: 4985-94. PMID 22795901 DOI: 10.1016/J.Bmc.2012.06.029 |
0.446 |
|
| 2009 |
Patrone JD, Yao J, Scott NE, Dotson GD. Selective inhibitors of bacterial phosphopantothenoylcysteine synthetase. Journal of the American Chemical Society. 131: 16340-1. PMID 19902973 DOI: 10.1021/Ja906537F |
0.633 |
|
| 2009 |
Yao J, Dotson GD. Kinetic characterization of human phosphopantothenoylcysteine synthetase. Biochimica Et Biophysica Acta. 1794: 1743-50. PMID 19683078 DOI: 10.1016/J.Bbapap.2009.08.008 |
0.734 |
|
| 2009 |
Yao J, Patrone JD, Dotson GD. Characterization and kinetics of phosphopantothenoylcysteine synthetase from Enterococcus faecalis. Biochemistry. 48: 2799-806. PMID 19182993 DOI: 10.1021/Bi802240W |
0.632 |
|
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