☰

Jiaxin Wu, Ph.D. - Publications

Affiliations: 
2008 The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Biochemistry, General Biophysics, Pharmacology
Tree Info Similar researchers PubMed Report error

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Chen Y, Fujita T, Zhang D, Doan H, Pinkaew D, Liu Z, Wu J, Koide Y, Chiu A, Lin CC, Chang JY, Ruan KH, Fujise K. Physical and functional antagonism between tumor suppressor protein p53 and fortilin, an anti-apoptotic protein. The Journal of Biological Chemistry. 286: 32575-85. PMID 21795694 DOI: 10.1074/jbc.M110.217836  0.464
2010 Chillar A, Wu J, Cervantes V, Ruan KH. Structural and functional analysis of the C-terminus of Galphaq in complex with the human thromboxane A2 receptor provides evidence of constitutive activity. Biochemistry. 49: 6365-74. PMID 20590159 DOI: 10.1021/Bi100047N  0.629
2009 Ruan KH, Cervantes V, Wu J. Ligand-specific conformation determines agonist activation and antagonist blockade in purified human thromboxane A2 receptor. Biochemistry. 48: 3157-65. PMID 19170518 DOI: 10.1021/Bi801443G  0.615
2008 Chillar A, Wu J, So SP, Ruan KH. Involvement of non-conserved residues important for PGE2 binding to the constrained EP3 eLP2 using NMR and site-directed mutagenesis. Febs Letters. 582: 2863-8. PMID 18652829 DOI: 10.1016/J.Febslet.2008.07.018  0.621
2008 Ruan KH, Wijaya C, Cervantes V, Wu J. Characterization of the prostaglandin H2 mimic: binding to the purified human thromboxane A2 receptor in solution. Archives of Biochemistry and Biophysics. 477: 396-403. PMID 18590695 DOI: 10.1016/J.Abb.2008.05.022  0.604
2008 Ruan KH, Cervantes V, Wu J. A simple, quick, and high-yield preparation of the human thromboxane A2 receptor in full size for structural studies. Biochemistry. 47: 6819-26. PMID 18529068 DOI: 10.1021/Bi702501G  0.573
2008 Ruan KH, Wu J, Cervantes V. Characterization of the substrate mimic bound to engineered prostacyclin synthase in solution using high-resolution NMR spectroscopy and mutagenesis: implication of the molecular mechanism in biosynthesis of prostacyclin. Biochemistry. 47: 680-8. PMID 18081314 DOI: 10.1021/Bi701671Q  0.581
2008 Wu J, Feng M, Ruan KH. Assembling NMR structures for the intracellular loops of the human thromboxane A2 receptor: implication of the G protein-coupling pocket. Archives of Biochemistry and Biophysics. 470: 73-82. PMID 18073117 DOI: 10.1016/J.Abb.2007.11.016  0.649
2006 Zhang L, Wu J, Ruan KH. Solution structure of the first intracellular loop of prostacyclin receptor and implication of its interaction with the C-terminal segment of G alpha s protein. Biochemistry. 45: 1734-44. PMID 16460020 DOI: 10.1021/Bi0515669  0.65
2005 Ruan KH, Wu J, Wang LH. Solution structure of a common substrate mimetic of cyclooxygenase-downstream synthases bound to an engineered thromboxane A2 synthase using a high-resolution NMR technique. Archives of Biochemistry and Biophysics. 444: 165-73. PMID 16297851 DOI: 10.1016/J.Abb.2005.10.010  0.616
2005 Ruan CH, Wu J, Ruan KH. A strategy using NMR peptide structures of thromboxane A2 receptor as templates to construct ligand-recognition pocket of prostacyclin receptor. Bmc Biochemistry. 6: 23. PMID 16271145 DOI: 10.1186/1471-2091-6-23  0.628
2005 Zhang L, Huang G, Wu J, Ruan KH. A profile of the residues in the first intracellular loop critical for Gs-mediated signaling of human prostacyclin receptor characterized by an integrative approach of NMR-experiment and mutagenesis. Biochemistry. 44: 11389-401. PMID 16114876 DOI: 10.1021/Bi050483P  0.686
2005 Ruan KH, Deng H, Wu J, So SP. The N-terminal membrane anchor domain of the membrane-bound prostacyclin synthase involved in the substrate presentation of the coupling reaction with cyclooxygenase. Archives of Biochemistry and Biophysics. 435: 372-81. PMID 15708381 DOI: 10.1016/J.Abb.2004.12.018  0.552
2004 Ruan KH, Wu J, So SP, Jenkins LA, Ruan CH. NMR structure of the thromboxane A2 receptor ligand recognition pocket. European Journal of Biochemistry / Febs. 271: 3006-16. PMID 15233797 DOI: 10.1111/J.1432-1033.2004.04232.X  0.649
2004 Geng L, Wu J, So SP, Huang G, Ruan KH. Structural and functional characterization of the first intracellular loop of human thromboxane A2 receptor. Archives of Biochemistry and Biophysics. 423: 253-65. PMID 15001390 DOI: 10.1016/J.Abb.2004.01.001  0.672
2003 Ruan KH, Wu J, So SP, Jenkins LA. Evidence of the residues involved in ligand recognition in the second extracellular loop of the prostacyclin receptor characterized by high resolution 2D NMR techniques. Archives of Biochemistry and Biophysics. 418: 25-33. PMID 13679079 DOI: 10.1016/S0003-9861(03)00401-6  0.672
2003 Wu J, So SP, Ruan KH. Solution structure of the third extracellular loop of human thromboxane A2 receptor. Archives of Biochemistry and Biophysics. 414: 287-93. PMID 12781781  0.662
2003 Deng H, Wu J, So SP, Ruan KH. Identification of the residues in the helix F/G loop important to catalytic function of membrane-bound prostacyclin synthase. Biochemistry. 42: 5609-17. PMID 12741817 DOI: 10.1021/Bi026749Z  0.62
2003 Wu J, So SP, Ruan KH. Determination of the membrane contact residues and solution structure of the helix F/G loop of prostaglandin I2 synthase. Archives of Biochemistry and Biophysics. 411: 27-35. PMID 12590920  0.578
2003 So SP, Wu J, Huang G, Huang A, Li D, Ruan KH. Identification of residues important for ligand binding of thromboxane A2 receptor in the second extracellular loop using the NMR experiment-guided mutagenesis approach. The Journal of Biological Chemistry. 278: 10922-7. PMID 12551898 DOI: 10.1074/Jbc.M209337200  0.67
2002 Ruan KH, So SP, Zheng W, Wu J, Li D, Kung J. Solution structure and topology of the N-terminal membrane anchor domain of a microsomal cytochrome P450: prostaglandin I2 synthase. The Biochemical Journal. 368: 721-8. PMID 12193162 DOI: 10.1042/Bj20021001  0.606
2001 Ruan KH, So SP, Wu J, Li D, Huang A, Kung J. Solution structure of the second extracellular loop of human thromboxane A2 receptor. Biochemistry. 40: 275-80. PMID 11141080 DOI: 10.1021/Bi001867C  0.687
1998 Frillingos S, Sahin-Tóth M, Wu J, Kaback HR. Cys-scanning mutagenesis: A novel approach to structure-function relationships in polytopic membrane proteins Faseb Journal. 12: 1281-1299. PMID 9761772 DOI: 10.1096/Fasebj.12.13.1281  0.325
1998 Lin Y, Li W, Wu J, Zhang H, Colman RW. Fourier transform infrared (FT-IR) spectroscopic studies of peptide models for interaction of the binding regions of high molecular weight kininogen and prekallikrein. Thrombosis Research. 90: 65-72. PMID 9684759 DOI: 10.1016/S0049-3848(98)00032-2  0.34
Show low-probability matches.