Sean P. Spencer, Ph.D. - Publications

Affiliations: 
2013 Immunology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology, Microbiology Biology, Nutrition

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bhattacharjee A, Burr AHP, Overacre-Delgoffe AE, Tometich JT, Yang D, Huckestein BR, Linehan JL, Spencer SP, Hall JA, Harrison OJ, Morais da Fonseca D, Norton EB, Belkaid Y, Hand TW. Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy. Immunity. PMID 34348118 DOI: 10.1016/j.immuni.2021.07.005  0.573
2020 Culver RN, Spencer SP, Huang KC. Colons or semi-colons: punctuating the regional variation of intestinal microbial-immune interactions. Nature Reviews. Gastroenterology & Hepatology. PMID 32322050 DOI: 10.1038/S41575-020-0302-Z  0.485
2019 Spencer SP, Fragiadakis GK, Sonnenburg JL. Pursuing Human-Relevant Gut Microbiota-Immune Interactions. Immunity. 51: 225-239. PMID 31433970 DOI: 10.1016/J.Immuni.2019.08.002  0.439
2019 Virtue AT, McCright SJ, Wright JM, Jimenez MT, Mowel WK, Kotzin JJ, Joannas L, Basavappa MG, Spencer SP, Clark ML, Eisennagel SH, Williams A, Levy M, Manne S, Henrickson SE, et al. The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs. Science Translational Medicine. 11. PMID 31189717 DOI: 10.1126/Scitranslmed.Aav1892  0.326
2019 Kotzin JJ, Iseka F, Wright J, Basavappa MG, Clark ML, Ali MA, Abdel-Hakeem MS, Robertson TF, Mowel WK, Joannas L, Neal VD, Spencer SP, Syrett CM, Anguera MC, Williams A, et al. The long noncoding RNA regulates CD8 T cells in response to viral infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 31138702 DOI: 10.1073/Pnas.1819457116  0.461
2018 Bortnick A, Chernova I, Spencer SP, Allman D. No strict requirement for eosinophils for bone marrow plasma cell survival. European Journal of Immunology. PMID 29442367 DOI: 10.1002/Eji.201747229  0.351
2017 Mowel WK, McCright SJ, Kotzin JJ, Collet MA, Uyar A, Chen X, DeLaney A, Spencer SP, Virtue AT, Yang E, Villarino A, Kurachi M, Dunagin MC, Pritchard GH, Stein J, et al. Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA. Immunity. 47: 435-449.e8. PMID 28930659 DOI: 10.1016/J.Immuni.2017.08.012  0.353
2016 Kotzin JJ, Spencer SP, McCright SJ, Kumar DB, Collet MA, Mowel WK, Elliott EN, Uyar A, Makiya MA, Dunagin MC, Harman CC, Virtue AT, Zhu S, Bailis W, Stein J, et al. The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. Nature. PMID 27525555 DOI: 10.1038/Nature19346  0.389
2016 Wilhelm C, Harrison OJ, Schmitt V, Pelletier M, Spencer SP, Urban JF, Ploch M, Ramalingam TR, Siegel RM, Belkaid Y. Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection. The Journal of Experimental Medicine. PMID 27432938 DOI: 10.1084/Jem.20151448  0.63
2014 Yagi R, Zhong C, Northrup DL, Yu F, Bouladoux N, Spencer S, Hu G, Barron L, Sharma S, Nakayama T, Belkaid Y, Zhao K, Zhu J. The transcription factor GATA3 is critical for the development of all IL-7Rα-expressing innate lymphoid cells. Immunity. 40: 378-88. PMID 24631153 DOI: 10.1016/J.Immuni.2014.01.012  0.618
2014 Mortha A, Chudnovskiy A, Hashimoto D, Bogunovic M, Spencer SP, Belkaid Y, Merad M. Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis. Science (New York, N.Y.). 343: 1249288. PMID 24625929 DOI: 10.1126/Science.1249288  0.649
2014 Spencer SP, Wilhelm C, Yang Q, Hall JA, Bouladoux N, Boyd A, Nutman TB, Urban JF, Wang J, Ramalingam TR, Bhandoola A, Wynn TA, Belkaid Y. Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity. Science (New York, N.Y.). 343: 432-7. PMID 24458645 DOI: 10.1126/Science.1247606  0.64
2014 Korn LL, Thomas HL, Hubbeling HG, Spencer SP, Sinha R, Simkins HM, Salzman NH, Bushman FD, Laufer TM. Conventional CD4+ T cells regulate IL-22-producing intestinal innate lymphoid cells. Mucosal Immunology. 7: 1045-57. PMID 24448096 DOI: 10.1038/Mi.2013.121  0.526
2013 Klebanoff CA, Spencer SP, Torabi-Parizi P, Grainger JR, Roychoudhuri R, Ji Y, Sukumar M, Muranski P, Scott CD, Hall JA, Ferreyra GA, Leonardi AJ, Borman ZA, Wang J, Palmer DC, et al. Retinoic acid controls the homeostasis of pre-cDC-derived splenic and intestinal dendritic cells. The Journal of Experimental Medicine. 210: 1961-76. PMID 23999499 DOI: 10.1084/Jem.20122508  0.596
2013 Klebanoff CA, Spencer S, Roychoudhuri R, Ji Y, Sukumar M, Muranski P, Napoli JL, Gattinoni L, Belkaid Y, Restifo NP. Induction of an acute vitamin A-deficient state following total body irradiation impairs anti-tumor immunity by altering the homeostasis of pre-cDC derived dendritic cells Journal For Immunotherapy of Cancer. 1. DOI: 10.1186/2051-1426-1-S1-P121  0.632
2012 Sciumé G, Hirahara K, Takahashi H, Laurence A, Villarino AV, Singleton KL, Spencer SP, Wilhelm C, Poholek AC, Vahedi G, Kanno Y, Belkaid Y, O'Shea JJ. Distinct requirements for T-bet in gut innate lymphoid cells. The Journal of Experimental Medicine. 209: 2331-8. PMID 23209316 DOI: 10.1084/Jem.20122097  0.616
2012 Spencer SP, Belkaid Y. Dietary and commensal derived nutrients: shaping mucosal and systemic immunity. Current Opinion in Immunology. 24: 379-84. PMID 22857854 DOI: 10.1016/J.Coi.2012.07.006  0.619
2012 Naik S, Bouladoux N, Wilhelm C, Molloy MJ, Salcedo R, Kastenmuller W, Deming C, Quinones M, Koo L, Conlan S, Spencer S, Hall JA, Dzutsev A, Kong H, Campbell DJ, et al. Compartmentalized control of skin immunity by resident commensals. Science (New York, N.Y.). 337: 1115-9. PMID 22837383 DOI: 10.1126/Science.1225152  0.676
2011 Hall JA, Grainger JR, Spencer SP, Belkaid Y. The role of retinoic acid in tolerance and immunity. Immunity. 35: 13-22. PMID 21777796 DOI: 10.1016/J.Immuni.2011.07.002  0.593
2010 Saenz SA, Siracusa MC, Perrigoue JG, Spencer SP, Urban JF, Tocker JE, Budelsky AL, Kleinschek MA, Kastelein RA, Kambayashi T, Bhandoola A, Artis D. IL25 elicits a multipotent progenitor cell population that promotes T(H)2 cytokine responses. Nature. 464: 1362-6. PMID 20200520 DOI: 10.1038/Nature08901  0.458
2007 Loffredo JT, Friedrich TC, León EJ, Stephany JJ, Rodrigues DS, Spencer SP, Bean AT, Beal DR, Burwitz BJ, Rudersdorf RA, Wallace LT, Piaskowski SM, May GE, Sidney J, Gostick E, et al. CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation. Plos One. 2: e1152. PMID 18000532 DOI: 10.1371/Journal.Pone.0001152  0.377
2007 Sacha JB, Chung C, Reed J, Jonas AK, Bean AT, Spencer SP, Lee W, Vojnov L, Rudersdorf R, Friedrich TC, Wilson NA, Lifson JD, Watkins DI. Pol-specific CD8+ T cells recognize simian immunodeficiency virus-infected cells prior to Nef-mediated major histocompatibility complex class I downregulation. Journal of Virology. 81: 11703-12. PMID 17699580 DOI: 10.1128/Jvi.00926-07  0.414
2007 Sacha JB, Chung C, Rakasz EG, Spencer SP, Jonas AK, Bean AT, Lee W, Burwitz BJ, Stephany JJ, Loffredo JT, Allison DB, Adnan S, Hoji A, Wilson NA, Friedrich TC, et al. Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression. Journal of Immunology (Baltimore, Md. : 1950). 178: 2746-54. PMID 17312117 DOI: 10.4049/Jimmunol.178.5.2746  0.394
2007 Loffredo JT, Burwitz BJ, Rakasz EG, Spencer SP, Stephany JJ, Vela JP, Martin SR, Reed J, Piaskowski SM, Furlott J, Weisgrau KL, Rodrigues DS, Soma T, Napoé G, Friedrich TC, et al. The antiviral efficacy of simian immunodeficiency virus-specific CD8+ T cells is unrelated to epitope specificity and is abrogated by viral escape. Journal of Virology. 81: 2624-34. PMID 17192314 DOI: 10.1128/Jvi.01912-06  0.406
2005 Loffredo JT, Rakasz EG, Giraldo JP, Spencer SP, Grafton KK, Martin SR, Napoé G, Yant LJ, Wilson NA, Watkins DI. Tat(28-35)SL8-specific CD8+ T lymphocytes are more effective than Gag(181-189)CM9-specific CD8+ T lymphocytes at suppressing simian immunodeficiency virus replication in a functional in vitro assay. Journal of Virology. 79: 14986-91. PMID 16282500 DOI: 10.1128/Jvi.79.23.14986-14991.2005  0.384
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