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Timothy S. Blackwell - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
Cell Biology
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256 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vannan A, Lyu R, Williams AL, Negretti NM, Mee ED, Hirsh J, Hirsh S, Nichols DS, Calvi CL, Taylor CJ, Polosukhin VV, Serezani AP, McCall AS, Gokey JJ, Shim H, ... ... Blackwell TS, et al. Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis. Biorxiv : the Preprint Server For Biology. PMID 38168317 DOI: 10.1101/2023.12.15.571954  0.321
2023 DiGiovanni GT, Han W, Sherrill TP, Taylor CJ, Nichols DS, Geis NM, Singha UK, Calvi CL, McCall AS, Dixon MM, Liu Y, Jang JH, Gutor SS, Polosukhin VV, Blackwell TS, et al. Epithelial Yap/Taz are required for functional alveolar regeneration following acute lung injury. Jci Insight. PMID 37676731 DOI: 10.1172/jci.insight.173374  0.38
2023 Han W, Tanjore H, Liu Y, Hunt RP, Gutor SS, Serezani APM, Blackwell TS. Identification and Characterization of Alveolar and Recruited Lung Macrophages during Acute Lung Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 37042701 DOI: 10.4049/jimmunol.2200694  0.373
2022 Suzuki T, Kropski JA, Chen J, Carrier EJ, Chen X, Sherrill TP, Winters NI, Camarata JE, Polosukhin VV, Han W, Rathinasabapathy A, Gutor S, Gulleman P, Sabusap C, Banovich NE, ... ... Blackwell TS, et al. Thromboxane-Prostanoid Receptor Signaling Drives Persistent Fibroblast Activation in Pulmonary Fibrosis. American Journal of Respiratory and Critical Care Medicine. PMID 35728047 DOI: 10.1164/rccm.202106-1503OC  0.309
2020 Benjamin JT, Plosa E, Sucre J, van der Meer R, Dave S, Gutor SS, Nichols D, Gulleman P, Jetter C, Han W, Xin MK, Dinella PC, Catanzarite A, Kook S, Dolma K, ... ... Blackwell TS, et al. Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD. The Journal of Clinical Investigation. PMID 33108351 DOI: 10.1172/JCI139481  0.372
2020 Hufnagel DH, Wilson AJ, Saxon J, Blackwell TS, Watkins J, Khabele D, Crispens MA, Yull FE, Beeghly-Fadiel A. Expression of p52, a non-canonical NF-kappaB transcription factor, is associated with poor ovarian cancer prognosis. Biomarker Research. 8: 45. PMID 32974032 DOI: 10.1186/S40364-020-00227-Y  0.346
2020 Richmond BW, Mansouri S, Serezani A, Novitskiy S, Blackburn JB, Du RH, Fuseini H, Gutor S, Han W, Schaff J, Vasiukov G, Xin MK, Newcomb DC, Jin L, Blackwell TS, et al. Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD. Mucosal Immunology. PMID 32968197 DOI: 10.1038/s41385-020-00344-9  0.325
2020 Habermann AC, Gutierrez AJ, Bui LT, Yahn SL, Winters NI, Calvi CL, Peter L, Chung MI, Taylor CJ, Jetter C, Raju L, Roberson J, Ding G, Wood L, Sucre JMS, ... ... Blackwell TS, et al. Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis. Science Advances. 6: eaba1972. PMID 32832598 DOI: 10.1126/Sciadv.Aba1972  0.441
2020 Davenport ML, Sherrill TP, Blackwell TS, Edmonds MD. Perfusion and Inflation of the Mouse Lung for Tumor Histology. Journal of Visualized Experiments : Jove. PMID 32831298 DOI: 10.3791/60605  0.409
2020 Song W, Kim LC, Han W, Hou Y, Edwards D, Wang S, Blackwell TS, Cheng F, Brantley-Sieders DM, Chen J. Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer. Molecular Cancer Research : McR. PMID 32753469 DOI: 10.1158/1541-7786.Mcr-20-0075  0.377
2020 Han W, Fessel JP, Sherrill T, Kocurek EG, Yull FE, Blackwell TS. Enhanced Expression of Catalase in Mitochondria Modulates NF-κB-Dependent Lung Inflammation through Alteration of Metabolic Activity in Macrophages. Journal of Immunology (Baltimore, Md. : 1950). PMID 32601098 DOI: 10.4049/Jimmunol.1900820  0.513
2020 Sahoo D, Zaramela LS, Hernandez GE, Mai U, Taheri S, Dang D, Stouch AN, Medal RM, McCoy AM, Aschner JL, Blackwell TS, Zengler K, Prince LS. Transcriptional profiling of lung macrophages identifies a predictive signature for inflammatory lung disease in preterm infants. Communications Biology. 3: 259. PMID 32444859 DOI: 10.1038/s42003-020-0985-2  0.343
2020 Vasiukov G, Novitskaya T, Zijlstra A, Owens P, Ye F, Zhao Z, Moses HL, Blackwell T, Feoktistov I, Novitskiy SV. Myeloid cell-derived TGF-beta signaling regulates ECM deposition in mammary carcinoma via adenosine-dependent mechanisms. Cancer Research. PMID 32312837 DOI: 10.1158/0008-5472.Can-19-3954  0.33
2020 Sucre JMS, Vickers KC, Benjamin JT, Plosa EJ, Jetter CS, Cutrone A, Ransom M, Anderson Z, Sheng Q, Fensterheim BA, Ambalavanan N, Millis B, Lee E, Zijlstra A, Königshoff M, ... Blackwell TS, et al. Hyperoxia Injury in the Developing Lung is Mediated by Mesenchymal Expression of Wnt5A. American Journal of Respiratory and Critical Care Medicine. PMID 32023086 DOI: 10.1164/Rccm.201908-1513Oc  0.381
2020 Salisbury ML, Hewlett JC, Ding G, Markin CR, Douglas K, Mason W, Guttentag A, Phillips JA, Cogan JD, Reiss S, Mitchell DB, Wu P, Young LR, Lancaster LH, Loyd JE, ... ... Blackwell TS, et al. Development and Progression of Radiologic Abnormalities in Individuals at Risk for Familial ILD. American Journal of Respiratory and Critical Care Medicine. PMID 32011901 DOI: 10.1164/Rccm.201909-1834Oc  0.352
2020 Habermann AC, Gutierrez AJ, Bui LT, Yahn SL, Winters NI, Calvi CL, Peter L, Chung M, Taylor CJ, Jetter C, Raju L, Roberson J, Ding G, Wood L, Sucre JMS, ... ... Blackwell TS, et al. Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis Science Advances. 6: eaba1972. DOI: 10.1126/sciadv.aba1972  0.332
2020 Plosa E, Sucre J, Gulleman P, Blackwell T. A19 Epithelial Beta 1 Integrin Regulates Lung Cancer Susceptibility Through NF-kB Signaling Journal of Thoracic Oncology. 15: S18. DOI: 10.1016/J.Jtho.2019.12.048  0.386
2019 Novitskiy SV, Zaynagetdinov R, Vasiukov G, Gutor S, Han W, Serezani A, Matafonov A, Gleaves LA, Sherrill TP, Polosukhin VV, Blackwell TS. Gas6/MerTK signaling is negatively regulated by NF-κB and supports lung carcinogenesis. Oncotarget. 10: 7031-7042. PMID 31903163 DOI: 10.18632/Oncotarget.27345  0.534
2019 Plosa EJ, Benjamin JT, Sucre JM, Gulleman PM, Gleaves LA, Han W, Kook S, Polosukhin VV, Haake SM, Guttentag SH, Young LR, Pozzi A, Blackwell TS, Zent R. β1 integrin regulates adult lung alveolar epithelial cell inflammation. Jci Insight. PMID 31873073 DOI: 10.1172/Jci.Insight.129259  0.47
2019 Mathai SK, Humphries S, Kropski JA, Blackwell TS, Powers J, Walts AD, Markin C, Woodward J, Chung JH, Brown KK, Steele MP, Loyd JE, Schwarz MI, Fingerlin T, Yang IV, et al. variant is associated with visually and quantitatively detected preclinical pulmonary fibrosis. Thorax. PMID 31558622 DOI: 10.1136/Thoraxjnl-2018-212430  0.313
2019 Winters NI, Burman A, Kropski JA, Blackwell TS. Epithelial Injury and Dysfunction in the Pathogenesis of Idiopathic PulmonaryFibrosis. The American Journal of the Medical Sciences. 357: 374-378. PMID 31010463 DOI: 10.1016/J.Amjms.2019.01.010  0.333
2019 Kropski JA, Blackwell TS. Progress in Understanding and Treating Idiopathic Pulmonary Fibrosis. Annual Review of Medicine. 70: 211-224. PMID 30691371 DOI: 10.1146/Annurev-Med-041317-102715  0.332
2019 Hufnagel D, Wilson AJ, Saxon J, Blackwell T, Khabele D, Crispens MA, Beeghly-Fadiel A, Yull F. Abstract 1573: Non-canonical NF-kappaB signaling in the tumor microenvironment in relation to ovarian cancer survival Cancer Research. 79: 1573-1573. DOI: 10.1158/1538-7445.Sabcs18-1573  0.366
2018 Richmond BW, Du RH, Marshall C, Pietenpol J, Polosukhin VV, Blackwell TS. p73 Is Required for pIgR Expression in the Respiratory Epithelium. Annals of the American Thoracic Society. 15: S290. PMID 30759000 DOI: 10.1513/Annalsats.201806-410Mg  0.342
2018 Bloodworth NC, Clark CR, West JD, Snider JC, Gaskill C, Shay S, Scott C, Bastarache J, Gladson S, Moore C, D'Amico R, Brittain EL, Tanjore H, Blackwell TS, Majka SM, et al. Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening via Serotonin 2B Receptor Dependent Mechanism. Circulation Research. 123: e51-e64. PMID 30566041 DOI: 10.1161/Circresaha.118.313397  0.321
2018 Morrison RJ, Katsantonis NG, Motz KM, Hillel AT, Garrett CG, Netterville JL, Wootten CT, Majka SM, Blackwell TS, Drake WP, Gelbard A. Pathologic Fibroblasts in Idiopathic Subglottic Stenosis Amplify Local Inflammatory Signals. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 194599818803584. PMID 30322354 DOI: 10.1177/0194599818803584  0.331
2018 Celada LJ, Kropski JA, Herazo-Maya JD, Luo W, Creecy A, Abad AT, Chioma OS, Lee G, Hassell NE, Shaginurova GI, Wang Y, Johnson JE, Kerrigan A, Mason WR, Baughman RP, ... ... Blackwell TS, et al. PD-1 up-regulation on CD4 T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production. Science Translational Medicine. 10. PMID 30257954 DOI: 10.1126/Scitranslmed.Aar8356  0.333
2018 Burman A, Kropski JA, Calvi CL, Serezani AP, Pascoalino BD, Han W, Sherrill T, Gleaves L, Lawson WE, Young LR, Blackwell TS, Tanjore H. Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein. Jci Insight. 3. PMID 30135303 DOI: 10.1172/Jci.Insight.99543  0.425
2018 Blackwell TS. Lung injury and fibrosis induced by a mutant form of surfactant protein C. The Journal of Clinical Investigation. PMID 30102252 DOI: 10.1172/Jci122727  0.462
2018 Wilfong EM, Lentz RJ, Guttentag A, Tolle JJ, Johnson JE, Kropski JA, Kendall PL, Blackwell TS, Crofford LJ. Interstitial Pneumonia with Autoimmune Features: An emerging challenge at the intersection of rheumatology and pulmonology. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30058242 DOI: 10.1002/Art.40679  0.304
2018 Finch DK, Stolberg VR, Ferguson J, Alikaj H, Kady MR, Richmond BW, Polosukhin VV, Blackwell TS, McCloskey L, Curtis JL, Freeman CM. Lung Dendritic Cells Drive NK Cytotoxicity in Chronic Obstructive Pulmonary Disease via IL-15Rα. American Journal of Respiratory and Critical Care Medicine. PMID 29676596 DOI: 10.1164/Rccm.201712-2513Oc  0.409
2018 Saxon JA, Yu H, Polosukhin VV, Stathopoulos GT, Gleaves LA, McLoed AG, Massion PP, Yull FE, Zhao Z, Blackwell TS. p52 expression enhances lung cancer progression. Scientific Reports. 8: 6078. PMID 29666445 DOI: 10.1038/S41598-018-24488-8  0.495
2018 Hewlett JC, Kropski JA, Blackwell TS. Idiopathic pulmonary fibrosis: Epithelial-mesenchymal interactions and emerging therapeutic targets. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29625182 DOI: 10.1016/J.Matbio.2018.03.021  0.426
2018 Sucre JMS, Jetter CS, Loomans H, Williams J, Plosa EJ, Benjamin JT, Young LR, Kropski JA, Calvi CL, Kook S, Wang P, Gleaves L, Eskaros A, Goetzl L, Blackwell TS, et al. Successful Establishment of Primary Type 2 Alveolar Epithelium with 3D Organotypic Co-culture. American Journal of Respiratory Cell and Molecular Biology. PMID 29625013 DOI: 10.1165/Rcmb.2017-0442Ma  0.372
2018 Vreka M, Lilis I, Papageorgopoulou M, Giotopoulou GA, Lianou M, Giopanou I, Kanellakis NI, Spella M, Agalioti T, Armenis V, Goldmann T, Marwitz S, Yull FE, Blackwell TS, Pasparakis M, et al. ΙκΒ kinase α is required for development and progression of KRAS-mutant lung adenocarcinoma. Cancer Research. PMID 29588349 DOI: 10.1158/0008-5472.Can-17-1944  0.496
2018 Burman A, Tanjore H, Blackwell TS. Endoplasmic reticulum stress in pulmonary fibrosis. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 29567124 DOI: 10.1016/J.Matbio.2018.03.015  0.365
2018 Irvin AE, Jhala G, Zhao Y, Blackwell TS, Krishnamurthy B, Thomas HE, Kay TWH. NF-κB is weakly activated in the NOD mouse model of type 1 diabetes. Scientific Reports. 8: 4217. PMID 29523846 DOI: 10.1038/S41598-018-22738-3  0.39
2018 Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou GA, Krontira AC, Iliopoulou M, Kanellakis NI, Agalioti T, Giannou AD, Jones-Paris C, Iwakura Y, Kardamakis D, ... Blackwell TS, et al. Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion. Nature Communications. 9: 672. PMID 29445180 DOI: 10.1038/S41467-018-03051-Z  0.339
2018 Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G, Maher TM, Molina-Molina M, Noble PW, Raghu G, Richeldi L, Schwarz MI, Selman M, Wuyts WA, Schwartz DA. Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic? The Lancet. Respiratory Medicine. 6: 154-160. PMID 29413083 DOI: 10.1016/S2213-2600(18)30007-9  0.361
2018 Sucre JMS, Deutsch GH, Jetter C, Ambalavanan N, Benjamin JT, Gleaves LA, Millis BA, Young LR, Blackwell TS, Kropski JA, Guttentag SH. A Shared Pattern of β-catenin Activation in Bronchopulmonary Dysplasia and Idiopathic Pulmonary Fibrosis. The American Journal of Pathology. PMID 29355514 DOI: 10.1016/J.Ajpath.2017.12.004  0.398
2018 Richmond BW, Du RH, Han W, Benjamin JT, Meer RV, Gleaves L, Guo M, McKissack A, Zhang Y, Cheng DS, Polosukhin VV, Blackwell TS. Bacterial-derived Neutrophilic Inflammation Drives Lung Remodeling in a Mouse Model of COPD. American Journal of Respiratory Cell and Molecular Biology. PMID 29314863 DOI: 10.1165/Rcmb.2017-0329Oc  0.493
2018 Kropski JA, Blackwell TS. Endoplasmic reticulum stress in the pathogenesis of fibrotic disease. The Journal of Clinical Investigation. 128: 64-73. PMID 29293089 DOI: 10.1172/Jci93560  0.305
2018 Allen RM, Zhao S, Ramirez-Solano MA, Zhu W, Richmond BW, Blackwell T, Sheng Q, Vickers KC. Abstract 576: LDL-Trafficked Small RNAs Promote Atherosclerosis through TLR Signaling in Macrophages Arteriosclerosis, Thrombosis, and Vascular Biology. 38. DOI: 10.1161/Atvb.38.Suppl_1.576  0.308
2017 McCoy AM, Herington JL, Stouch AN, Mukherjee AB, Lakhdari O, Blackwell TS, Prince LS. IKKβ Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis. The American Journal of Pathology. PMID 28923684 DOI: 10.1016/J.Ajpath.2017.08.013  0.528
2017 Lentz RJ, Taylor TM, Kropski JA, Sandler KL, Johnson JE, Blackwell TS, Maldonado F, Rickman OB. Utility of Flexible Bronchoscopic Cryobiopsy for Diagnosis of Diffuse Parenchymal Lung Diseases. Journal of Bronchology & Interventional Pulmonology. PMID 28796717 DOI: 10.1097/Lbr.0000000000000401  0.35
2017 Kropski JA, Young LR, Blackwell TS, Loyd JE. Reply: The Genetic Diagnosis of Interstitial Lung Disease: A Need for an International Consensus. American Journal of Respiratory and Critical Care Medicine. 195: 1539-1540. PMID 28569574 DOI: 10.1164/Rccm.201612-2520Le  0.359
2017 Gaskill CF, Carrier EJ, Kropski JA, Bloodworth NC, Menon S, Foronjy RF, Taketo MM, Hong CC, Austin ED, West JD, Means AL, Loyd JE, Merryman WD, Hemnes AR, De Langhe S, ... Blackwell TS, et al. Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction. The Journal of Clinical Investigation. PMID 28463231 DOI: 10.1172/Jci88629  0.372
2017 Medal RM, Im AM, Yamamoto Y, Lakhdari O, Blackwell TS, Hoffman HM, Sahoo D, Prince LS. The Innate Immune Response in Fetal Lung Mesenchymal Cells Targets VEGFR2 Expression and Activity. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00554.2016. PMID 28336813 DOI: 10.1152/Ajplung.00554.2016  0.491
2017 Lu J, Guo S, Xue X, Chen Q, Ge J, Zhuo Y, Zhong H, Chen B, Zhao M, Han W, Suzuki T, Zhu M, Xia L, Schneider C, Blackwell TS, et al. Identification of a Novel Series of Anti-inflammatory and Anti-oxidative Phospholipid Oxidation Products Containing Cyclopentenone Moiety in vitro and in vivo: Implication in Atherosclerosis. The Journal of Biological Chemistry. PMID 28202546 DOI: 10.1074/Jbc.M116.751909  0.357
2016 Polosukhin VV, Richmond BW, Du RH, Cates JM, Wu P, Nian H, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS. SIgA Deficiency in Individual Small Airways is Associated with Persistent Inflammation and Remodeling. American Journal of Respiratory and Critical Care Medicine. PMID 27911098 DOI: 10.1164/Rccm.201604-0759Oc  0.368
2016 Young LR, Gulleman PM, Short CW, Tanjore H, Sherrill T, Qi A, McBride AP, Zaynagetdinov R, Benjamin JT, Lawson WE, Novitskiy SV, Blackwell TS. Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome. Jci Insight. 1: e88947. PMID 27777976 DOI: 10.1172/Jci.Insight.88947  0.473
2016 Saxon JA, Sherrill TP, Polosukhin VV, Sai J, Zaynagetdinov R, McLoed AG, Gulleman PM, Barham W, Cheng DS, Hunt RP, Gleaves LA, Richmond A, Young LR, Yull FE, Blackwell TS. Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment. Oncoimmunology. 5: e1168549. PMID 27471643 DOI: 10.1080/2162402X.2016.1168549  0.507
2016 McLoed AG, Sherrill TP, Cheng DS, Han W, Saxon JA, Gleaves LA, Wu P, Polosukhin VV, Karin M, Yull FE, Stathopoulos GT, Georgoulias V, Zaynagetdinov R, Blackwell TS. Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer. Cell Reports. PMID 27320908 DOI: 10.1016/J.Celrep.2016.05.085  0.414
2016 Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, ... ... Blackwell TS, et al. Idiopathic subglottic stenosis is associated with activation of the inflammatory IL-17A/IL-23 axis. The Laryngoscope. PMID 27296163 DOI: 10.1002/Lary.26098  0.34
2016 Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, ... ... Blackwell TS, et al. Molecular analysis of idiopathic subglottic stenosis for Mycobacterium species. The Laryngoscope. PMID 27295947 DOI: 10.1002/Lary.26097  0.324
2016 Nevel RJ, Garnett ET, Worrell JA, Morton RL, Nogee LM, Blackwell TS, Young LR. Persistent Lung Disease in Adults with NKX2.1 Mutation and Familial Neuroendocrine Cell Hyperplasia of Infancy (NEHI). Annals of the American Thoracic Society. PMID 27187870 DOI: 10.1513/Annalsats.201603-155Bc  0.346
2016 Benjamin JT, van der Meer R, Im AM, Plosa EJ, Zaynagetdinov R, Burman A, Havrilla ME, Gleaves LA, Polosukhin VV, Deutsch GH, Yanagisawa H, Davidson JM, Prince LS, Young LR, Blackwell TS. Epithelial-Derived Inflammation Disrupts Elastin Assembly and Alters Saccular Stage Lung Development. The American Journal of Pathology. PMID 27181406 DOI: 10.1016/J.Ajpath.2016.02.016  0.496
2016 Mont S, Davies SS, Roberts Second LJ, Mernaugh RL, McDonald WH, Segal BH, Zackert W, Kropski JA, Blackwell TS, Sekhar KR, Galligan JJ, Massion PP, Marnett LJ, Travis EL, Freeman ML. Accumulation of isolevuglandin-modified protein in normal and fibrotic lung. Scientific Reports. 6: 24919. PMID 27118599 DOI: 10.1038/Srep24919  0.365
2016 Richmond BW, Brucker RM, Han W, Du RH, Zhang Y, Cheng DS, Gleaves L, Abdolrasulnia R, Polosukhina D, Clark PE, Bordenstein SR, Blackwell TS, Polosukhin VV. Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency. Nature Communications. 7: 11240. PMID 27046438 DOI: 10.1038/Ncomms11240  0.491
2016 Stouch AN, McCoy AM, Greer RM, Lakhdari O, Yull FE, Blackwell TS, Hoffman HM, Prince LS. IL-1β and Inflammasome Activity Link Inflammation to Abnormal Fetal Airway Development. Journal of Immunology (Baltimore, Md. : 1950). 196: 3411-20. PMID 26951798 DOI: 10.4049/Jimmunol.1500906  0.47
2016 Nyhoff LE, Barron B, Johnson EM, Bonami RH, Maseda D, Fensterheim BA, Han W, Blackwell TS, Crofford LJ, Kendall PL. Bruton's tyrosine kinase deficiency inhibits autoimmune arthritis but fails to block immune complex-mediated inflammatory arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26945549 DOI: 10.1002/Art.39657  0.317
2016 Saxon JA, Cheng DS, Han W, Polosukhin VV, McLoed AG, Richmond BW, Gleaves LA, Tanjore H, Sherrill TP, Barham W, Yull FE, Blackwell TS. p52 Overexpression Increases Epithelial Apoptosis, Enhances Lung Injury, and Reduces Survival after Lipopolysaccharide Treatment. Journal of Immunology (Baltimore, Md. : 1950). 196: 1891-9. PMID 26773153 DOI: 10.4049/Jimmunol.1501555  0.495
2016 Edmonds MD, Boyd KL, Moyo TK, Mitra R, Duszynski RJ, Arrate MP, Chen X, Zhao Z, Blackwell TS, Eischen CM. Abstract LB-168: MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-168  0.367
2016 Mont S, Davies SS, Roberts LJ, Mernaugh RL, McDonald WH, Segal BH, Kropski JA, Blackwell TS, Sekhar KR, Galligan JJ, Marnett LJ, Freeman ML. Abstract 3050: Proteotoxic isolevuglandins are a central feature of radiation-induced pulmonary injury Cancer Research. 76: 3050-3050. DOI: 10.1158/1538-7445.Am2016-3050  0.419
2016 Saxon JA, Sherrill TP, Polosukhin VV, Sai J, Zaynagetdinov R, McLoed AG, Gulleman PM, Barham W, Cheng DS, Hunt RP, Gleaves LA, Richmond A, Young LR, Yull FE, Blackwell TS. Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment Oncoimmunology. 5. DOI: 10.1080/2162402X.2016.1168549  0.41
2015 Zaynagetdinov R, Sherrill TP, Gleaves LA, Hunt P, Han W, McLoed AG, Saxon JA, Tanjore H, Gulleman PM, Young LR, Blackwell TS. Chronic NF-κB activation links COPD and lung cancer through generation of an immunosuppressive microenvironment in the lungs. Oncotarget. PMID 26756215 DOI: 10.18632/Oncotarget.6562  0.549
2015 Bryant AJ, Robinson LJ, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, McClellan LJ, Polosukhin VV, Tanjore H, McConaha ME, Gleaves LA, Talati MA, Hemnes AR, Fessel JP, ... ... Blackwell TS, et al. Expression of mutant bone morphogenetic protein receptor II worsens pulmonary hypertension secondary to pulmonary fibrosis. Pulmonary Circulation. 5: 681-90. PMID 26697175 DOI: 10.1086/683811  0.396
2015 Edmonds MD, Boyd KL, Moyo T, Mitra R, Duszynski R, Arrate MP, Chen X, Zhao Z, Blackwell TS, Andl T, Eischen CM. MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer. The Journal of Clinical Investigation. PMID 26657862 DOI: 10.1172/Jci82720  0.333
2015 Bryant AJ, Carrick RP, McConaha ME, Jones BR, Shay SD, Moore CS, Blackwell TR, Gladson S, Penner NL, Burman A, Tanjore H, Hemnes AR, Karwandyar AK, Polosukhin VV, Talati MA, ... ... Blackwell TS, et al. ENDOTHELIAL HIF SIGNALING REGULATES PULMONARY FIBROSIS-ASSOCIATED PULMONARY HYPERTENSION. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00258.2015. PMID 26637636 DOI: 10.1152/Ajplung.00258.2015  0.365
2015 Du RH, Richmond BW, Blackwell TS, Cates JM, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS, Polosukhin VV. Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease. Virchows Archiv : An International Journal of Pathology. PMID 26432569 DOI: 10.1007/S00428-015-1854-0  0.376
2015 Barham W, Chen L, Tikhomirov O, Onishko H, Gleaves L, Stricker TP, Blackwell TS, Yull FE. Aberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ. Bmc Cancer. 15: 647. PMID 26424146 DOI: 10.1186/S12885-015-1652-8  0.393
2015 Cyphert TJ, Morris RT, House LM, Barnes TM, Otero YF, Barham WJ, Hunt RP, Zaynagetdinov R, Yull FE, Blackwell TS, McGuinness OP. NF-κB-dependent airway inflammation triggers systemic insulin resistance. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 309: R1144-52. PMID 26377563 DOI: 10.1152/Ajpregu.00442.2014  0.414
2015 Giannou AD, Marazioti A, Spella M, Kanellakis NI, Apostolopoulou H, Psallidas I, Prijovich ZM, Vreka M, Zazara DE, Lilis I, Papaleonidopoulos V, Kairi CA, Patmanidi AL, Giopanou I, Spiropoulou N, ... ... Blackwell TS, et al. Mast cells mediate malignant pleural effusion formation. The Journal of Clinical Investigation. 125: 2317-34. PMID 25915587 DOI: 10.1172/Jci79840  0.402
2015 Aldrich MC, Munro HM, Mumma M, Grogan EL, Massion PP, Blackwell TS, Blot WJ. Chronic obstructive pulmonary disease and subsequent overall and lung cancer mortality in low-income adults. Plos One. 10: e0121805. PMID 25811837 DOI: 10.1371/Journal.Pone.0121805  0.378
2015 Zaynagetdinov R, Sherrill TP, Gleaves LA, McLoed AG, Saxon JA, Habermann AC, Connelly L, Dulek D, Peebles RS, Fingleton B, Yull FE, Stathopoulos GT, Blackwell TS. Interleukin-5 facilitates lung metastasis by modulating the immune microenvironment. Cancer Research. 75: 1624-34. PMID 25691457 DOI: 10.1158/0008-5472.Can-14-2379  0.449
2015 Wang H, Chen X, Su Y, Paueksakon P, Hu W, Zhang MZ, Harris RC, Blackwell TS, Zent R, Pozzi A. p47(phox) contributes to albuminuria and kidney fibrosis in mice. Kidney International. 87: 948-62. PMID 25565313 DOI: 10.1038/Ki.2014.386  0.342
2015 Kropski JA, Pritchett JM, Zoz DF, Crossno PF, Markin C, Garnett ET, Degryse AL, Mitchell DB, Polosukhin VV, Rickman OB, Choi L, Cheng DS, McConaha ME, Jones BR, Gleaves LA, ... ... Blackwell TS, et al. Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease. American Journal of Respiratory and Critical Care Medicine. 191: 417-26. PMID 25389906 DOI: 10.1164/Rccm.201406-1162Oc  0.369
2015 Han W, Zaynagetdinov R, Yull FE, Polosukhin VV, Gleaves LA, Tanjore H, Young LR, Peterson TE, Manning HC, Prince LS, Blackwell TS. Molecular Imaging of Folate Receptor β-Positive Macrophages during Acute Lung Inflammation. American Journal of Respiratory Cell and Molecular Biology. 53: 50-9. PMID 25375039 DOI: 10.1165/Rcmb.2014-0289Oc  0.527
2015 Barham W, Tikhomirov O, Ortega R, Saskowski J, Thompson CS, Wilson A, Blackwell T, Mirafzali Z, Khabele D, Giorgio T, Yull FE. Abstract 294: A novel cancer therapeutic strategy: inducing cytotoxic functions in tumor-associated macrophages Immunology. 75: 294-294. DOI: 10.1158/1538-7445.Am2015-294  0.313
2014 Plosa EJ, Young LR, Gulleman PM, Polosukhin VV, Zaynagetdinov R, Benjamin JT, Im AM, van der Meer R, Gleaves LA, Bulus N, Han W, Prince LS, Blackwell TS, Zent R. Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization. Development (Cambridge, England). 141: 4751-62. PMID 25395457 DOI: 10.1242/Jcs.167338  0.447
2014 Paulson NB, Gilbertsen AJ, Dalluge JJ, Welchlin CW, Hughes J, Han W, Blackwell TS, Laguna TA, Williams BJ. The arginine decarboxylase pathways of host and pathogen interact to impact inflammatory pathways in the lung. Plos One. 9: e111441. PMID 25350753 DOI: 10.1371/Journal.Pone.0111441  0.428
2014 Polosukhin VV, Polosukhin IV, Hoskins A, Han W, Abdolrasulnia R, Blackwell TS, Dworski R. Glutathione S-transferase M1 modulates allergen-induced NF-κB activation in asthmatic airway epithelium. Allergy. 69: 1666-72. PMID 25118837 DOI: 10.1111/All.12506  0.446
2014 Stouch AN, Zaynagetdinov R, Barham WJ, Stinnett AM, Slaughter JC, Yull FE, Hoffman HM, Blackwell TS, Prince LS. IκB kinase activity drives fetal lung macrophage maturation along a non-M1/M2 paradigm. Journal of Immunology (Baltimore, Md. : 1950). 193: 1184-93. PMID 24981452 DOI: 10.4049/Jimmunol.1302516  0.488
2014 Dulek DE, Newcomb DC, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill TP, Blackwell TS, Moore ML, Boyd KL, Kolls JK, Peebles RS. Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner. Infection and Immunity. 82: 3723-39. PMID 24958709 DOI: 10.1128/Iai.00035-14  0.379
2014 Talati M, West J, Zaynagetdinov R, Hong CC, Han W, Blackwell T, Robinson L, Blackwell TS, Lane K. BMP pathway regulation of and by macrophages Plos One. 9. PMID 24713633 DOI: 10.1371/Journal.Pone.0094119  0.444
2014 Shi C, Washington MK, Chaturvedi R, Drosos Y, Revetta FL, Weaver CJ, Buzhardt E, Yull FE, Blackwell TS, Sosa-Pineda B, Whitehead RH, Beauchamp RD, Wilson KT, Means AL. Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction. Laboratory Investigation; a Journal of Technical Methods and Pathology. 94: 409-21. PMID 24535260 DOI: 10.1038/Labinvest.2014.10  0.314
2014 Kropski JA, Mitchell DB, Markin C, Polosukhin VV, Choi L, Johnson JE, Lawson WE, Phillips JA, Cogan JD, Blackwell TS, Loyd JE. A novel dyskerin (DKC1) mutation is associated with familial interstitial pneumonia. Chest. 146: e1-7. PMID 24504062 DOI: 10.1378/Chest.13-2224  0.322
2014 Sun X, He S, Wara AK, Icli B, Shvartz E, Tesmenitsky Y, Belkin N, Li D, Blackwell TS, Sukhova GK, Croce K, Feinberg MW. Systemic delivery of microRNA-181b inhibits nuclear factor-κB activation, vascular inflammation, and atherosclerosis in apolipoprotein E-deficient mice. Circulation Research. 114: 32-40. PMID 24084690 DOI: 10.1161/Circresaha.113.302089  0.336
2014 Talati M, Mutlak H, Lane K, Han W, Hemnes A, Mutlak O, Blackwell T, Zaynagetdinov R, Blackwell T, West J. NF-κB Activation Exacerbates, but Is not Required for Murine Bmpr2-Related Pulmonary Hypertension Diseases. 2: 148-167. DOI: 10.3390/Diseases2020148  0.467
2014 McLoed A, Zaynagetdinov R, Sherrill T, Yull F, Blackwell T. Abstract 3667: Attenuation of NF-κB signaling in myeloid cells enhances urethane-induced lung tumorigenesis via neutrophil-derived IL-1β Cancer Research. 74: 3667-3667. DOI: 10.1158/1538-7445.Am2014-3667  0.533
2014 Ausborn JA, Cheng D, Polosukhin V, Han W, Yull F, Blackwell T. Abstract 1673: Alternative NF-κB signaling promotes inflammatory cell recruitment and lung tumor formation Cancer Research. 74: 1673-1673. DOI: 10.1158/1538-7445.Am2014-1673  0.534
2013 Li H, Han W, Polosukhin V, Yull FE, Segal BH, Xie CM, Blackwell TS. NF-κB inhibition after cecal ligation and puncture reduces sepsis-associated lung injury without altering bacterial host defense. Mediators of Inflammation. 2013: 503213. PMID 24347827 DOI: 10.1155/2013/503213  0.462
2013 Kropski JA, Pritchett JM, Mason WR, Sivarajan L, Gleaves LA, Johnson JE, Lancaster LH, Lawson WE, Blackwell TS, Steele MP, Loyd JE, Rickman OB. Bronchoscopic cryobiopsy for the diagnosis of diffuse parenchymal lung disease. Plos One. 8: e78674. PMID 24265706 DOI: 10.1371/Journal.Pone.0078674  0.384
2013 Kim KH, Sadikot RT, Xiao L, Christman JW, Freeman ML, Chan JY, Oh YK, Blackwell TS, Joo M. Nrf2 is essential for the expression of lipocalin-prostaglandin D synthase induced by prostaglandin D2. Free Radical Biology & Medicine. 65: 1134-42. PMID 24029383 DOI: 10.1016/J.Freeradbiomed.2013.08.192  0.445
2013 Sanders PN, Koval OM, Jaffer OA, Prasad AM, Businga TR, Scott JA, Hayden PJ, Luczak ED, Dickey DD, Allamargot C, Olivier AK, Meyerholz DK, Robison AJ, Winder DG, Blackwell TS, et al. CaMKII is essential for the proasthmatic effects of oxidation. Science Translational Medicine. 5: 195ra97. PMID 23884469 DOI: 10.1126/Scitranslmed.3006135  0.342
2013 Sevin CM, Newcomb DC, Toki S, Han W, Sherrill TP, Boswell MG, Zhu Z, Collins RD, Boyd KL, Goleniewska K, Huckabee MM, Blackwell TS, Peebles RS. Deficiency of gp91phox inhibits allergic airway inflammation. American Journal of Respiratory Cell and Molecular Biology. 49: 396-402. PMID 23590311 DOI: 10.1165/Rcmb.2012-0442Oc  0.41
2013 Carver BJ, Plosa EJ, Stinnett AM, Blackwell TS, Prince LS. Interactions between NF-κB and SP3 connect inflammatory signaling with reduced FGF-10 expression. The Journal of Biological Chemistry. 288: 15318-25. PMID 23558680 DOI: 10.1074/Jbc.M112.447318  0.432
2013 Han W, Li H, Cai J, Gleaves LA, Polosukhin VV, Segal BH, Yull FE, Blackwell TS. NADPH oxidase limits lipopolysaccharide-induced lung inflammation and injury in mice through reduction-oxidation regulation of NF-κB activity. Journal of Immunology (Baltimore, Md. : 1950). 190: 4786-94. PMID 23530143 DOI: 10.4049/Jimmunol.1201809  0.52
2013 Lawson WE, Blackwell TS. β-Catenin and CCNs in lung epithelial repair. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L579-81. PMID 23525784 DOI: 10.1152/Ajplung.00073.2013  0.396
2013 Grimm MJ, Vethanayagam RR, Almyroudis NG, Dennis CG, Khan AN, D'Auria AC, Singel KL, Davidson BA, Knight PR, Blackwell TS, Hohl TM, Mansour MK, Vyas JM, Röhm M, Urban CF, et al. Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice. Journal of Immunology (Baltimore, Md. : 1950). 190: 4175-84. PMID 23509361 DOI: 10.4049/Jimmunol.1202800  0.468
2013 Tanjore H, Degryse AL, Crossno PF, Xu XC, McConaha ME, Jones BR, Polosukhin VV, Bryant AJ, Cheng DS, Newcomb DC, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE. β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin. American Journal of Respiratory and Critical Care Medicine. 187: 630-9. PMID 23306543 DOI: 10.1164/Rccm.201205-0972Oc  0.44
2013 Davidson BA, Vethanayagam RR, Grimm MJ, Mullan BA, Raghavendran K, Blackwell TS, Freeman ML, Ayyasamy V, Singh KK, Sporn MB, Itagaki K, Hauser CJ, Knight PR, Segal BH. NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury. Journal of Immunology (Baltimore, Md. : 1950). 190: 1714-24. PMID 23296708 DOI: 10.4049/Jimmunol.1202410  0.419
2013 Kropski JA, Lawson WE, Young LR, Blackwell TS. Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. Disease Models & Mechanisms. 6: 9-17. PMID 23268535 DOI: 10.1242/Dmm.010736  0.421
2013 Tanjore H, Lawson WE, Blackwell TS. Endoplasmic reticulum stress as a pro-fibrotic stimulus. Biochimica Et Biophysica Acta. 1832: 940-7. PMID 23201247 DOI: 10.1016/J.Bbadis.2012.11.011  0.313
2013 McLoed A, Zaynagetdinov R, Sherrill T, Yull F, Blackwell T. Abstract 2875: NF-κB signaling in myeloid cells limits urethane-induced lung tumorigenesis. Cancer Research. 73: 2875-2875. DOI: 10.1158/1538-7445.Am2013-2875  0.552
2013 Ausborn JA, Sherrill T, Zaynagetdinov R, Polosukhin V, McMahon F, Yull F, Blackwell T. Abstract 2873: Epithelial NF-κB signaling is required for different functions in Kras- and EGFR-mediated lung tumorigenesis. Cancer Research. 73: 2873-2873. DOI: 10.1158/1538-7445.Am2013-2873  0.538
2013 Barham W, Tikhomirov O, Chen L, Ortega R, Gleaves L, Onishko H, Sherrill T, Connelly L, Blackwell TS, Yull FE. Abstract 1545: Education of macrophages through modulation of NF-kappaB: an opportunity for targeted therapy. Cancer Research. 73: 1545-1545. DOI: 10.1158/1538-7445.Am2013-1545  0.45
2012 Han W, Li H, Segal BH, Blackwell TS. Bioluminescence imaging of NADPH oxidase activity in different animal models. Journal of Visualized Experiments : Jove. PMID 23117583 DOI: 10.3791/3925  0.4
2012 Young LR, Gulleman PM, Bridges JP, Weaver TE, Deutsch GH, Blackwell TS, McCormack FX. The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome. American Journal of Respiratory and Critical Care Medicine. 186: 1014-24. PMID 23043085 DOI: 10.1164/Rccm.201207-1206Oc  0.467
2012 Barham W, Sherrill T, Connelly L, Blackwell TS, Yull FE. Intraductal injection of LPS as a mouse model of mastitis: signaling visualized via an NF-κB reporter transgenic. Journal of Visualized Experiments : Jove. e4030. PMID 22971993 DOI: 10.3791/4030  0.397
2012 Tully JE, Nolin JD, Guala AS, Hoffman SM, Roberson EC, Lahue KG, Van Der Velden J, Anathy V, Blackwell TS, Janssen-Heininger YMW. Cooperation between classical and alternative NF-κB pathways regulates proinflammatory responses in epithelial cells American Journal of Respiratory Cell and Molecular Biology. 47: 497-508. PMID 22652196 DOI: 10.1165/Rcmb.2012-0014Oc  0.507
2012 Sun X, Icli B, Wara AK, Belkin N, He S, Kobzik L, Hunninghake GM, Vera MP, Blackwell TS, Baron RM, Feinberg MW. MicroRNA-181b regulates NF-κB-mediated vascular inflammation. The Journal of Clinical Investigation. 122: 1973-90. PMID 22622040 DOI: 10.1172/Jci61495  0.347
2012 Segal BH, Grimm MJ, Khan AN, Han W, Blackwell TS. Regulation of innate immunity by NADPH oxidase. Free Radical Biology & Medicine. 53: 72-80. PMID 22583699 DOI: 10.1016/J.Freeradbiomed.2012.04.022  0.395
2012 Karmouty-Quintana H, Zhong H, Acero L, Weng T, Melicoff E, West JD, Hemnes A, Grenz A, Eltzschig HK, Blackwell TS, Xia Y, Johnston RA, Zeng D, Belardinelli L, Blackburn MR. The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2546-57. PMID 22415303 DOI: 10.1096/Fj.11-200907  0.361
2012 Polosukhin VV, Degryse AL, Newcomb DC, Jones BR, Ware LB, Lee JW, Loyd JE, Blackwell TS, Lawson WE. Intratracheal bleomycin causes airway remodeling and airflow obstruction in mice. Experimental Lung Research. 38: 135-46. PMID 22394287 DOI: 10.3109/01902148.2012.658595  0.484
2012 Degryse AL, Xu XC, Newman JL, Mitchell DB, Tanjore H, Polosukhin VV, Jones BR, McMahon FB, Gleaves LA, Phillips JA, Cogan JD, Blackwell TS, Lawson WE. Telomerase deficiency does not alter bleomycin-induced fibrosis in mice. Experimental Lung Research. 38: 124-34. PMID 22394286 DOI: 10.3109/01902148.2012.658148  0.438
2012 Tanjore H, Blackwell TS, Lawson WE. Emerging evidence for endoplasmic reticulum stress in the pathogenesis of idiopathic pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L721-9. PMID 22287606 DOI: 10.1152/Ajplung.00410.2011  0.378
2012 Karabela SP, Psallidas I, Sherrill TP, Kairi CA, Zaynagetdinov R, Cheng DS, Vassiliou S, McMahon F, Gleaves LA, Han W, Stathopoulos I, Zakynthinos SG, Yull FE, Roussos C, Kalomenidis I, ... Blackwell TS, et al. Opposing effects of bortezomib-induced nuclear factor-κB inhibition on chemical lung carcinogenesis. Carcinogenesis. 33: 859-67. PMID 22287559 DOI: 10.1093/Carcin/Bgs024  0.543
2012 Torres-González E, Bueno M, Tanaka A, Krug LT, Cheng DS, Polosukhin VV, Sorescu D, Lawson WE, Blackwell TS, Rojas M, Mora AL. Role of endoplasmic reticulum stress in age-related susceptibility to lung fibrosis. American Journal of Respiratory Cell and Molecular Biology. 46: 748-56. PMID 22227563 DOI: 10.1165/Rcmb.2011-0224Oc  0.418
2012 Kropski JA, Lawson WE, Blackwell TS. Right place, right time: the evolving role of herpesvirus infection as a "second hit" in idiopathic pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L441-4. PMID 22180659 DOI: 10.1152/Ajplung.00335.2011  0.42
2012 Manni ML, Epperly MW, Han W, Blackwell TS, Duncan SR, Piganelli JD, Oury TD. Leukocyte-derived extracellular superoxide dismutase does not contribute to airspace EC-SOD after interstitial pulmonary injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L160-6. PMID 22003088 DOI: 10.1152/Ajplung.00360.2010  0.462
2012 Zaynagetdinov R, Stathopoulos GT, Sherrill TP, Cheng DS, McLoed AG, Ausborn JA, Polosukhin VV, Connelly L, Zhou W, Fingleton B, Peebles RS, Prince LS, Yull FE, Blackwell TS. Epithelial nuclear factor-κB signaling promotes lung carcinogenesis via recruitment of regulatory T lymphocytes. Oncogene. 31: 3164-76. PMID 22002309 DOI: 10.1038/onc.2011.480  0.452
2012 McLoed AG, Zaynagetdinov R, Sherrill T, Yull FE, Blackwell TS. Abstract 529: Impaired NF-κB signaling in myeloid cells enhances urethane-induced lung carcinogenesis Cancer Research. 72: 529-529. DOI: 10.1158/1538-7445.Am2012-529  0.56
2012 Onishko H, Barham W, Chen L, Cheng D, Tikhomirov O, Connelly L, Blackwell T, Yull FE. Abstract 5262: Disruption of alternative and classical NF-kappaB signaling patterns: Connections to branching morphogenesis and mammary tumorigenesis Cancer Research. 72: 5262-5262. DOI: 10.1158/1538-7445.Am2012-5262  0.371
2012 Ausborn JA, Sherrill T, Zaynagetdinov R, Polosukhin V, McMahon F, Yull F, Blackwell TS. Abstract 313: K-ras- and EGFR-mediated lung tumor formation require epithelial NF-κB signaling to modulate the inflammatory microenvironment Cancer Research. 72: 313-313. DOI: 10.1158/1538-7445.Am2012-313  0.505
2012 Zaynagetdinov R, Karabela SP, Psallidas I, Sherrill TP, Kairi CA, Cheng D, Vassiliou S, Gleaves LA, Han W, Zakynthinos SG, Yull FE, Roussos C, Kalomenidis I, Blackwell TS, Stathopoulos GT. Abstract 2873: Opposing effects of NF-κB inhibition during chemical lung carcinogenesis Cancer Research. 72: 2873-2873. DOI: 10.1158/1538-7445.Am2012-2873  0.537
2011 Vethanayagam RR, Almyroudis NG, Grimm MJ, Lewandowski DC, Pham CT, Blackwell TS, Petraitiene R, Petraitis V, Walsh TJ, Urban CF, Segal BH. Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense. Plos One. 6: e28149. PMID 22163282 DOI: 10.1371/Journal.Pone.0028149  0.357
2011 Zaynagetdinov R, Sherrill TP, Polosukhin VV, Han W, Ausborn JA, McLoed AG, McMahon FB, Gleaves LA, Degryse AL, Stathopoulos GT, Yull FE, Blackwell TS. A critical role for macrophages in promotion of urethane-induced lung carcinogenesis. Journal of Immunology (Baltimore, Md. : 1950). 187: 5703-11. PMID 22048774 DOI: 10.4049/Jimmunol.1100558  0.469
2011 Chung S, Sundar IK, Hwang JW, Yull FE, Blackwell TS, Kinnula VL, Bulger M, Yao H, Rahman I. NF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs. Plos One. 6: e23488. PMID 21887257 DOI: 10.1371/Journal.Pone.0023488  0.377
2011 Connelly L, Barham W, Onishko HM, Chen L, Sherrill TP, Zabuawala T, Ostrowski MC, Blackwell TS, Yull FE. NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model. Breast Cancer Research : Bcr. 13: R83. PMID 21884585 DOI: 10.1186/Bcr2935  0.496
2011 Chen AC, Arany PR, Huang YY, Tomkinson EM, Sharma SK, Kharkwal GB, Saleem T, Mooney D, Yull FE, Blackwell TS, Hamblin MR. Low-level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts. Plos One. 6: e22453. PMID 21814580 DOI: 10.1371/Journal.Pone.0022453  0.36
2011 Blackwell TS, Hipps AN, Yamamoto Y, Han W, Barham WJ, Ostrowski MC, Yull FE, Prince LS. NF-κB signaling in fetal lung macrophages disrupts airway morphogenesis. Journal of Immunology (Baltimore, Md. : 1950). 187: 2740-7. PMID 21775686 DOI: 10.4049/Jimmunol.1101495  0.55
2011 Zhou W, Dowell DR, Geraci MW, Blackwell TS, Collins RD, Polosukhin VV, Lawson WE, Wu P, Sussan T, Biswal S, Goleniewska K, O'Neal J, Newcomb DC, Toki S, Morrow JD, et al. PGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expression. American Journal of Physiology. Lung Cellular and Molecular Physiology. 301: L615-22. PMID 21764988 DOI: 10.1152/Ajplung.00224.2010  0.413
2011 Tanjore H, Cheng DS, Degryse AL, Zoz DF, Abdolrasulnia R, Lawson WE, Blackwell TS. Alveolar epithelial cells undergo epithelial-to-mesenchymal transition in response to endoplasmic reticulum stress. The Journal of Biological Chemistry. 286: 30972-80. PMID 21757695 DOI: 10.1074/Jbc.M110.181164  0.334
2011 Lawson WE, Cheng DS, Degryse AL, Tanjore H, Polosukhin VV, Xu XC, Newcomb DC, Jones BR, Roldan J, Lane KB, Morrisey EE, Beers MF, Yull FE, Blackwell TS. Endoplasmic reticulum stress enhances fibrotic remodeling in the lungs. Proceedings of the National Academy of Sciences of the United States of America. 108: 10562-7. PMID 21670280 DOI: 10.1073/Pnas.1107559108  0.459
2011 Zoz DF, Lawson WE, Blackwell TS. Idiopathic pulmonary fibrosis: a disorder of epithelial cell dysfunction. The American Journal of the Medical Sciences. 341: 435-8. PMID 21613930 DOI: 10.1097/Maj.0B013E31821A9D8E  0.433
2011 Dworski R, Han W, Blackwell TS, Hoskins A, Freeman ML. Vitamin E prevents NRF2 suppression by allergens in asthmatic alveolar macrophages in vivo. Free Radical Biology & Medicine. 51: 516-21. PMID 21605660 DOI: 10.1016/J.Freeradbiomed.2011.04.040  0.397
2011 Polosukhin VV, Cates JM, Lawson WE, Milstone AP, Matafonov AG, Massion PP, Lee JW, Randell SH, Blackwell TS. Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium. The Journal of Pathology. 224: 203-11. PMID 21557221 DOI: 10.1002/Path.2863  0.372
2011 Polosukhin VV, Cates JM, Lawson WE, Zaynagetdinov R, Milstone AP, Massion PP, Ocak S, Ware LB, Lee JW, Bowler RP, Kononov AV, Randell SH, Blackwell TS. Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 184: 317-27. PMID 21512171 DOI: 10.1164/Rccm.201010-1629Oc  0.35
2011 Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, Boomershine CS, Ortiz C, Sherrill TP, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE. TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L887-97. PMID 21441353 DOI: 10.1152/Ajplung.00397.2010  0.493
2011 Lawson WE, Blackwell TS, Gauldie J. Let It Be: microRNAs impact interstitial lung disease. American Journal of Respiratory and Critical Care Medicine. 183: 1-2. PMID 21193781 DOI: 10.1164/Rccm.201009-1482Ed  0.379
2011 Connelly L, Barham W, Onishko HM, Sherrill T, Chodosh LA, Blackwell TS, Yull FE. Inhibition of NF-kappa B activity in mammary epithelium increases tumor latency and decreases tumor burden Oncogene. 30: 1402-1412. PMID 21076466 DOI: 10.1038/Onc.2010.521  0.359
2011 Grimm MJ, Vethanayagam RR, Almyroudis NG, Lewandowski D, Rall N, Blackwell TS, Segal BH. Role of NADPH oxidase in host defense against aspergillosis. Medical Mycology. 49: S144-9. PMID 20560866 DOI: 10.3109/13693786.2010.487077  0.354
2011 Zaynagetdinov R, Sherrill TP, Polosukhin VV, Han W, McMahon FB, Gleaves LA, Ausborn JA, McLoed AG, Yull FE, Blackwell TS. Abstract 451: Macrophages are critical for promotion of urethane-induced lung carcinogenesis during early stages Cancer Research. 71: 451-451. DOI: 10.1158/1538-7445.Am2011-451  0.428
2011 Barham W, Connelly L, Onishko HM, Chen L, Sherrill T, Zabuawala T, Ostrowski M, Blackwell T, Yull F. Abstract 2841: Inducible modulation of NF-kappaB in macrophages reveals that timing of intervention may be critical to therapeutic outcome during mammary tumorigenesis Cancer Research. 71: 2841-2841. DOI: 10.1158/1538-7445.Am2011-2841  0.431
2011 Sevin C, Newcomb D, Huckabee M, Goleniewska K, Blackwell T, Peebles R. Attenuated Allergic Airway Inflammation in gp91phox KO Mice is Due to Altered Dendritic Cell Function Journal of Allergy and Clinical Immunology. 127: AB259-AB259. DOI: 10.1016/J.Jaci.2010.12.1033  0.377
2010 Lee HJ, Joo M, Abdolrasulnia R, Young DG, Choi I, Ware LB, Blackwell TS, Christman BW. Peptidylarginine deiminase 2 suppresses inhibitory {kappa}B kinase activity in lipopolysaccharide-stimulated RAW 264.7 macrophages. The Journal of Biological Chemistry. 285: 39655-62. PMID 20937835 DOI: 10.1074/Jbc.M110.170290  0.431
2010 Benjamin JT, Carver BJ, Plosa EJ, Yamamoto Y, Miller JD, Liu JH, van der Meer R, Blackwell TS, Prince LS. NF-kappaB activation limits airway branching through inhibition of Sp1-mediated fibroblast growth factor-10 expression. Journal of Immunology (Baltimore, Md. : 1950). 185: 4896-903. PMID 20861353 DOI: 10.4049/Jimmunol.1001857  0.511
2010 Doris K, Karabela SP, Kairi CA, Simoes DC, Roussos C, Zakynthinos SG, Kalomenidis I, Blackwell TS, Stathopoulos GT. Allergic inflammation does not impact chemical-induced carcinogenesis in the lungs of mice. Respiratory Research. 11: 118. PMID 20796309 DOI: 10.1186/1465-9921-11-118  0.466
2010 Williams BJ, Dehnbostel J, Blackwell TS. Pseudomonas aeruginosa: host defence in lung diseases. Respirology (Carlton, Vic.). 15: 1037-56. PMID 20723140 DOI: 10.1111/J.1440-1843.2010.01819.X  0.365
2010 Degryse AL, Tanjore H, Xu XC, Polosukhin VV, Jones BR, McMahon FB, Gleaves LA, Blackwell TS, Lawson WE. Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L442-52. PMID 20562227 DOI: 10.1152/Ajplung.00026.2010  0.473
2010 Crossno PF, Polosukhin VV, Blackwell TS, Johnson JE, Markin C, Moore PE, Worrell JA, Stahlman MT, Phillips JA, Loyd JE, Cogan JD, Lawson WE. Identification of early interstitial lung disease in an individual with genetic variations in ABCA3 and SFTPC. Chest. 137: 969-73. PMID 20371530 DOI: 10.1378/Chest.09-0790  0.305
2010 Segal BH, Han W, Bushey JJ, Joo M, Bhatti Z, Feminella J, Dennis CG, Vethanayagam RR, Yull FE, Capitano M, Wallace PK, Minderman H, Christman JW, Sporn MB, Chan J, ... ... Blackwell TS, et al. NADPH oxidase limits innate immune responses in the lungs in mice. Plos One. 5: e9631. PMID 20300512 DOI: 10.1371/Journal.Pone.0009631  0.411
2010 Kobayashi H, Huang J, Ye F, Shyr Y, Blackwell TS, Lin PC. Interleukin-32beta propagates vascular inflammation and exacerbates sepsis in a mouse model. Plos One. 5: e9458. PMID 20221440 DOI: 10.1371/Journal.Pone.0009458  0.334
2010 Psallidas I, Karabela SP, Moschos C, Sherrill TP, Kollintza A, Magkouta S, Theodoropoulou P, Roussos C, Blackwell TS, Kalomenidis I, Stathopoulos GT. Specific effects of bortezomib against experimental malignant pleural effusion: a preclinical study. Molecular Cancer. 9: 56. PMID 20219102 DOI: 10.1186/1476-4598-9-56  0.453
2010 Connelly L, Barham W, Pigg R, Saint-Jean L, Sherrill T, Cheng DS, Chodosh LA, Blackwell TS, Yull FE. Activation of nuclear factor kappa B in mammary epithelium promotes milk loss during mammary development and infection. Journal of Cellular Physiology. 222: 73-81. PMID 19746431 DOI: 10.1002/Jcp.21922  0.409
2010 Connelly L, Barham W, Onishko HM, Zabuawala T, Ostrowski MC, Blackwell TS, Yull FE. Abstract 1352: Macrophage specific regulation reveals both pro- and anti-tumor effects of NF-kappaB during mammary tumor progression Cancer Research. 70: 1352-1352. DOI: 10.1158/1538-7445.Am10-1352  0.454
2010 Sevin C, Newcomb D, Goleniewska K, Blackwell T, Peebles R. Lack of p47phox, the Active Subunit of the NADPH Oxidase Complex, Augments Ovalbumin-induced Allergic Airway Inflammation in Mice Journal of Allergy and Clinical Immunology. 125: AB105. DOI: 10.1016/J.Jaci.2009.12.413  0.382
2009 Garantziotis S, Li Z, Potts EN, Lindsey JY, Stober VP, Polosukhin VV, Blackwell TS, Schwartz DA, Foster WM, Hollingsworth JW. TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation. American Journal of Respiratory and Critical Care Medicine. 181: 666-75. PMID 20007931 DOI: 10.1164/Rccm.200903-0381Oc  0.361
2009 Sheller JR, Polosukhin VV, Mitchell D, Cheng DS, Peebles RS, Blackwell TS. Nuclear factor kappa B induction in airway epithelium increases lung inflammation in allergen-challenged mice Experimental Lung Research. 35: 883-895. PMID 19995280 DOI: 10.3109/01902140903019710  0.459
2009 Chiang SH, Bazuine M, Lumeng CN, Geletka LM, Mowers J, White NM, Ma JT, Zhou J, Qi N, Westcott D, Delproposto JB, Blackwell TS, Yull FE, Saltiel AR. The protein kinase IKKepsilon regulates energy balance in obese mice. Cell. 138: 961-75. PMID 19737522 DOI: 10.1016/J.Cell.2009.06.046  0.315
2009 Ma LL, Gao X, Liu L, Xiang Z, Blackwell TS, Williams P, Chari RS, Yin DP. CpG oligodeoxynucleotide triggers the liver inflammatory reaction and abrogates spontaneous tolerance. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 15: 915-23. PMID 19642135 DOI: 10.1002/Lt.21771  0.301
2009 Tanjore H, Xu XC, Polosukhin VV, Degryse AL, Li B, Han W, Sherrill TP, Plieth D, Neilson EG, Blackwell TS, Lawson WE. Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. American Journal of Respiratory and Critical Care Medicine. 180: 657-65. PMID 19556518 DOI: 10.1164/Rccm.200903-0322Oc  0.441
2009 Bastarache JA, Blackwell TS. Development of animal models for the acute respiratory distress syndrome. Disease Models & Mechanisms. 2: 218-23. PMID 19407329 DOI: 10.1242/Dmm.001677  0.345
2009 Singh MV, Kapoun A, Higgins L, Kutschke W, Thurman JM, Zhang R, Singh M, Yang J, Guan X, Lowe JS, Weiss RM, Zimmermann K, Yull FE, Blackwell TS, Mohler PJ, et al. Ca2+/calmodulin-dependent kinase II triggers cell membrane injury by inducing complement factor B gene expression in the mouse heart. The Journal of Clinical Investigation. 119: 986-96. PMID 19273909 DOI: 10.1172/Jci35814  0.35
2009 Joo M, Kwon M, Cho YJ, Hu N, Pedchenko TV, Sadikot RT, Blackwell TS, Christman JW. Lipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L771-9. PMID 19181746 DOI: 10.1152/Ajplung.90320.2008  0.375
2009 Han W, Joo M, Everhart MB, Christman JW, Yull FE, Blackwell TS. Myeloid cells control termination of lung inflammation through the NF-kappaB pathway. American Journal of Physiology. Lung Cellular and Molecular Physiology. 296: L320-7. PMID 19098124 DOI: 10.1152/Ajplung.90485.2008  0.824
2009 Sadikot RT, Blackwell TS. Bioluminescence: imaging modality for in vitro and in vivo gene expression. Methods in Molecular Biology (Clifton, N.J.). 477: 383-94. PMID 19082962 DOI: 10.1007/978-1-60327-517-0_29  0.315
2008 Jin RJ, Lho Y, Connelly L, Wang Y, Yu X, Saint Jean L, Case TC, Ellwood-Yen K, Sawyers CL, Bhowmick NA, Blackwell TS, Yull FE, Matusik RJ. The nuclear factor-kappaB pathway controls the progression of prostate cancer to androgen-independent growth. Cancer Research. 68: 6762-9. PMID 18701501 DOI: 10.1158/0008-5472.Can-08-0107  0.304
2008 Chen SM, Cheng DS, Williams BJ, Sherrill TP, Han W, Chont M, Saint-Jean L, Christman JW, Sadikot RT, Yull FE, Blackwell TS. The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection. Clinical and Experimental Immunology. 153: 420-8. PMID 18647324 DOI: 10.1111/J.1365-2249.2008.03707.X  0.515
2008 Musiek ES, Brooks JD, Joo M, Brunoldi E, Porta A, Zanoni G, Vidari G, Blackwell TS, Montine TJ, Milne GL, McLaughlin B, Morrow JD. Electrophilic cyclopentenone neuroprostanes are anti-inflammatory mediators formed from the peroxidation of the omega-3 polyunsaturated fatty acid docosahexaenoic acid. The Journal of Biological Chemistry. 283: 19927-35. PMID 18490445 DOI: 10.1074/Jbc.M803625200  0.312
2008 Joo M, Kwon M, Azim AC, Sadikot RT, Blackwell TS, Christman JW. Genetic determination of the role of PU.1 in macrophage gene expression. Biochemical and Biophysical Research Communications. 372: 97-102. PMID 18485892 DOI: 10.1016/J.Bbrc.2008.04.189  0.369
2008 Lawson WE, Crossno PF, Polosukhin VV, Roldan J, Cheng DS, Lane KB, Blackwell TR, Xu C, Markin C, Ware LB, Miller GG, Loyd JE, Blackwell TS. Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: Association with altered surfactant protein processing and herpesvirus infection American Journal of Physiology - Lung Cellular and Molecular Physiology. 294. PMID 18390830 DOI: 10.1152/Ajplung.00382.2007  0.404
2008 Ma L, Xiang Z, Sherrill TP, Wang L, Blackwell TS, Williams P, Chong A, Chari R, Yin DP. Bioluminescence imaging visualizes activation of nuclear factor-kappaB in mouse cardiac transplantation. Transplantation. 85: 903-10. PMID 18360274 DOI: 10.1097/Tp.0B013E318166Cde1  0.318
2008 Stathopoulos GT, Sherrill TP, Han W, Sadikot RT, Yull FE, Blackwell TS, Fingleton B. Host nuclear factor-kappaB activation potentiates lung cancer metastasis. Molecular Cancer Research : McR. 6: 364-71. PMID 18337446 DOI: 10.1158/1541-7786.Mcr-07-0309  0.507
2008 Tager AM, LaCamera P, Shea BS, Campanella GS, Selman M, Zhao Z, Polosukhin V, Wain J, Karimi-Shah BA, Kim ND, Hart WK, Pardo A, Blackwell TS, Xu Y, Chun J, et al. The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak. Nature Medicine. 14: 45-54. PMID 18066075 DOI: 10.1038/Nm1685  0.409
2008 Stathopoulos GT, Sherrill TP, Han W, Sadikot RT, Polosukhin VV, Fingleton B, Yull FE, Blackwell TS. Use of bioluminescent imaging to investigate the role of nuclear factor-κΒ in experimental non-small cell lung cancer metastasis Clinical & Experimental Metastasis. 25: 43-51. PMID 18008176 DOI: 10.1007/S10585-007-9100-Z  0.49
2007 Stathopoulos GT, Sherrill TP, Cheng DS, Scoggins RM, Han W, Polosukhin VV, Connelly L, Yull FE, Fingleton B, Blackwell TS. Epithelial NF-kappaB activation promotes urethane-induced lung carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 18514-9. PMID 18000061 DOI: 10.1073/Pnas.0705316104  0.557
2007 Stathopoulos GT, Kollintza A, Moschos C, Psallidas I, Sherrill TP, Pitsinos EN, Vassiliou S, Karatza M, Papiris SA, Graf D, Orphanidou D, Light RW, Roussos C, Blackwell TS, Kalomenidis I. Tumor necrosis factor-alpha promotes malignant pleural effusion. Cancer Research. 67: 9825-34. PMID 17942913 DOI: 10.1158/0008-5472.Can-07-1064  0.318
2007 Zhang H, Lawson WE, Polosukhin VV, Pozzi A, Blackwell TS, Litingtung Y, Chiang C. Inhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in mice. The American Journal of Pathology. 171: 1113-26. PMID 17717145 DOI: 10.2353/Ajpath.2007.070226  0.461
2007 Joo M, Kwon M, Sadikot RT, Kingsley PJ, Marnett LJ, Blackwell TS, Peebles RS, Urade Y, Christman JW. Induction and function of lipocalin prostaglandin D synthase in host immunity Journal of Immunology. 179: 2565-2575. PMID 17675519 DOI: 10.4049/Jimmunol.179.4.2565  0.417
2007 Polosukhin VV, Lawson WE, Milstone AP, Egunova SM, Kulipanov AG, Tchuvakin SG, Massion PP, Blackwell TS. Association of progressive structural changes in the bronchial epithelium with subepithelial fibrous remodeling: a potential role for hypoxia. Virchows Archiv : An International Journal of Pathology. 451: 793-803. PMID 17674038 DOI: 10.1007/S00428-007-0469-5  0.357
2007 Park GY, Hu N, Wang X, Sadikot RT, Yull FE, Joo M, Peebles RS, Blackwell TS, Christman JW. Conditional regulation of cyclooxygenase‐2 in tracheobronchial epithelial cells modulates pulmonary immunity Clinical and Experimental Immunology. 150: 245-254. PMID 17672868 DOI: 10.1111/J.1365-2249.2007.03478.X  0.481
2007 Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC. Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L491-6. PMID 17545492 DOI: 10.1152/Ajplung.00009.2007  0.383
2007 Cheng DS, Han W, Chen SM, Sherrill TP, Chont M, Park GY, Sheller JR, Polosukhin VV, Christman JW, Yull FE, Blackwell TS. Airway epithelium controls lung inflammation and injury through the NF-κB pathway Journal of Immunology. 178: 6504-6513. PMID 17475880 DOI: 10.4049/Jimmunol.178.10.6504  0.558
2007 Sadikot RT, Zeng H, Azim AC, Joo M, Dey SK, Breyer RM, Peebles RS, Blackwell TS, Christman JW. Bacterial clearance of Pseudomonas aeruginosa is enhanced by the inhibition of COX-2. European Journal of Immunology. 37: 1001-9. PMID 17330822 DOI: 10.1002/Eji.200636636  0.438
2007 Connelly L, Robinson-Benion C, Chont M, Saint-Jean L, Li H, Polosukhin VV, Blackwell TS, Yull FE. A transgenic model reveals important roles for the NF-kappa B alternative pathway (p100/p52) in mammary development and links to tumorigenesis. The Journal of Biological Chemistry. 282: 10028-35. PMID 17261585 DOI: 10.1074/Jbc.M611300200  0.361
2007 Joo M, Wright JG, Hu NN, Sadikot RT, Park GY, Blackwell TS, Christman JW. Yin Yang 1 enhances cyclooxygenase-2 gene expression in macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1219-26. PMID 17220375 DOI: 10.1152/Ajplung.00474.2006  0.409
2007 Zhou W, Hashimoto K, Goleniewska K, O'Neal JF, Ji S, Blackwell TS, Fitzgerald GA, Egan KM, Geraci MW, Peebles RS. Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 702-10. PMID 17202330 DOI: 10.4049/Jimmunol.178.2.702  0.372
2007 Zhou W, Blackwell TS, Goleniewska K, O'Neal JF, Fitzgerald GA, Lucitt M, Breyer RM, Peebles RS. Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells. Journal of Leukocyte Biology. 81: 809-17. PMID 17135575 DOI: 10.1189/Jlb.0606375  0.318
2006 Gray KD, Simovic MO, Blackwell TS, Christman JW, May AK, Parman KS, Chapman WC, Stain SC. Activation of nuclear factor kappa B and severe hepatic necrosis may mediate systemic inflammation in choline-deficient/ethionine-supplemented diet-induced pancreatitis. Pancreas. 33: 260-7. PMID 17003648 DOI: 10.1097/01.Mpa.0000240599.95817.34  0.405
2006 Chen JX, Zeng H, Lawrence ML, Blackwell TS, Meyrick B. Angiopoietin-1-induced angiogenesis is modulated by endothelial NADPH oxidase. American Journal of Physiology. Heart and Circulatory Physiology. 291: H1563-72. PMID 16679392 DOI: 10.1152/Ajpheart.01081.2005  0.315
2006 Park GY, Wang X, Hu N, Pedchenko TV, Blackwell TS, Christman JW. NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha. The Journal of Biological Chemistry. 281: 18684-90. PMID 16675465 DOI: 10.1074/Jbc.M600733200  0.349
2006 Everhart MB, Han W, Sherrill TP, Arutiunov M, Polosukhin VV, Burke JR, Sadikot RT, Christman JW, Yull FE, Blackwell TS. Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury. Journal of Immunology (Baltimore, Md. : 1950). 176: 4995-5005. PMID 16585596 DOI: 10.4049/Jimmunol.176.8.4995  0.827
2006 Sadikot RT, Zeng H, Joo M, Everhart MB, Sherrill TP, Li B, Cheng DS, Yull FE, Christman JW, Blackwell TS. Targeted immunomodulation of the NF-kappaB pathway in airway epithelium impacts host defense against Pseudomonas aeruginosa. Journal of Immunology (Baltimore, Md. : 1950). 176: 4923-30. PMID 16585588 DOI: 10.4049/Jimmunol.176.8.4923  0.818
2006 Maus UA, Janzen S, Wall G, Srivastava M, Blackwell TS, Christman JW, Seeger W, Welte T, Lohmeyer J. Resident alveolar macrophages are replaced by recruited monocytes in response to endotoxin-induced lung inflammation. American Journal of Respiratory Cell and Molecular Biology. 35: 227-35. PMID 16543608 DOI: 10.1165/Rcmb.2005-0241Oc  0.455
2006 Dieperink HI, Blackwell TS, Prince LS. Hyperoxia and apoptosis in developing mouse lung mesenchyme. Pediatric Research. 59: 185-90. PMID 16439576 DOI: 10.1203/01.Pdr.0000196371.85945.3A  0.475
2006 Stathopoulos GT, Zhu Z, Everhart MB, Kalomenidis I, Lawson WE, Bilaceroglu S, Peterson TE, Mitchell D, Yull FE, Light RW, Blackwell TS. Nuclear factor-kappaB affects tumor progression in a mouse model of malignant pleural effusion. American Journal of Respiratory Cell and Molecular Biology. 34: 142-50. PMID 16210694 DOI: 10.1165/Rcmb.2005-0130Oc  0.799
2006 Glasgow S, Ramachandran S, Blackwell T, Mohanakumar T, Chapman W. IL-1β short interfering RNA (siRNA) ameliorates lung inflammatory response following liver injury Journal of Surgical Research. 130: 198. DOI: 10.1016/J.Jss.2005.11.103  0.347
2005 Lawson WE, Polosukhin VV, Stathopoulos GT, Zoia O, Han W, Lane KB, Li B, Donnelly EF, Holburn GE, Lewis KG, Collins RD, Hull WM, Glasser SW, Whitsett JA, Blackwell TS. Increased and prolonged pulmonary fibrosis in surfactant protein C-deficient mice following intratracheal bleomycin. The American Journal of Pathology. 167: 1267-77. PMID 16251411 DOI: 10.1016/S0002-9440(10)61214-X  0.457
2005 O'Donnell SM, Hansberger MW, Connolly JL, Chappell JD, Watson MJ, Pierce JM, Wetzel JD, Han W, Barton ES, Forrest JC, Valyi-Nagy T, Yull FE, Blackwell TS, Rottman JN, Sherry B, et al. Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease. The Journal of Clinical Investigation. 115: 2341-50. PMID 16100570 DOI: 10.1172/Jci22428  0.385
2005 Musiek ES, Gao L, Milne GL, Han W, Everhart MB, Wang D, Backlund MG, DuBois RN, Zanoni G, Vidari G, Blackwell TS, Morrow JD. Cyclopentenone isoprostanes inhibit the inflammatory response in macrophages. The Journal of Biological Chemistry. 280: 35562-70. PMID 16100121 DOI: 10.1074/Jbc.M504785200  0.787
2005 Pedchenko TV, Park GY, Joo M, Blackwell TS, Christman JW. Inducible binding of PU.1 and interacting proteins to the Toll-like receptor 4 promoter during endotoxemia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L429-37. PMID 16093364 DOI: 10.1152/Ajplung.00046.2005  0.421
2005 Curran CL, Blackwell TS, Christman JW. NF-kappaB: a therapeutic target in inflammatory diseases. Expert Opinion On Therapeutic Targets. 5: 197-204. PMID 15992176 DOI: 10.1517/14728222.5.2.197  0.407
2005 Cheng Q, Zhao Y, Lawson WE, Polosukhin VV, Johnson JE, Blackwell TS, Gailani D. The effects of intrinsic pathway protease deficiencies on plasminogen-deficient mice. Blood. 106: 3055-7. PMID 15985536 DOI: 10.1182/Blood-2005-02-0577  0.402
2005 Polosukhin VV, Stathopoulos GT, Lawson WE, Blackwell TS. Variability of interalveolar septal remodeling after bleomycin treatment in mice. Ultrastructural Pathology. 29: 53-64. PMID 15934165 DOI: 10.1080/019131290882286  0.432
2005 Joo M, Hahn YS, Kwon M, Sadikot RT, Blackwell TS, Christman JW. Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta. Journal of Virology. 79: 7648-57. PMID 15919917 DOI: 10.1128/Jvi.79.12.7648-7657.2005  0.331
2005 Sadikot RT, Blackwell TS, Christman JW, Prince AS. Pathogen-host interactions in Pseudomonas aeruginosa pneumonia. American Journal of Respiratory and Critical Care Medicine. 171: 1209-23. PMID 15695491 DOI: 10.1164/Rccm.200408-1044So  0.333
2005 Everhart MB, Han W, Parman KS, Polosukhin VV, Zeng H, Sadikot RT, Li B, Yull FE, Christman JW, Blackwell TS. Intratracheal administration of liposomal clodronate accelerates alveolar macrophage reconstitution following fetal liver transplantation. Journal of Leukocyte Biology. 77: 173-80. PMID 15563581 DOI: 10.1189/Jlb.1203647  0.813
2005 Maus UA, Wellmann S, Hampl C, Kuziel WA, Srivastava M, Mack M, Everhart MB, Blackwell TS, Christman JW, Schlöndorff D, Bohle RM, Seeger W, Lohmeyer J. CCR2-positive monocytes recruited to inflamed lungs downregulate local CCL2 chemokine levels. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L350-8. PMID 15516494 DOI: 10.1152/Ajplung.00061.2004  0.815
2004 Lawson WE, Polosukhin VV, Zoia O, Stathopoulos GT, Han W, Plieth D, Loyd JE, Neilson EG, Blackwell TS. Characterization of fibroblast-specific protein 1 in pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine. 171: 899-907. PMID 15618458 DOI: 10.1164/Rccm.200311-1535Oc  0.466
2004 Lawson WE, Grant SW, Ambrosini V, Womble KE, Dawson EP, Lane KB, Markin C, Renzoni E, Lympany P, Thomas AQ, Roldan J, Scott TA, Blackwell TS, Phillips JA, Loyd JE, et al. Genetic mutations in surfactant protein C are a rare cause of sporadic cases of IPF. Thorax. 59: 977-80. PMID 15516475 DOI: 10.1136/Thx.2004.026336  0.321
2004 Sadikot RT, Christman JW, Blackwell TS. Molecular targets for modulating lung inflammation and injury. Current Drug Targets. 5: 581-8. PMID 15270205 DOI: 10.2174/1389450043345281  0.484
2004 Maus UA, Srivastava M, Paton JC, Mack M, Everhart MB, Blackwell TS, Christman JW, Schlöndorff D, Seeger W, Lohmeyer J. Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space. Journal of Immunology (Baltimore, Md. : 1950). 173: 1307-12. PMID 15240724 DOI: 10.4049/Jimmunol.173.2.1307  0.817
2004 Tager AM, Kradin RL, LaCamera P, Bercury SD, Campanella GS, Leary CP, Polosukhin V, Zhao LH, Sakamoto H, Blackwell TS, Luster AD. Inhibition of pulmonary fibrosis by the chemokine IP-10/CXCL10. American Journal of Respiratory Cell and Molecular Biology. 31: 395-404. PMID 15205180 DOI: 10.1165/Rcmb.2004-0175Oc  0.45
2004 Joo M, Park GY, Wright JG, Blackwell TS, Atchison ML, Christman JW. Transcriptional regulation of the cyclooxygenase-2 gene in macrophages by PU.1. The Journal of Biological Chemistry. 279: 6658-65. PMID 14966110 DOI: 10.1074/Jbc.M306267200  0.326
2004 Sadikot RT, Zeng H, Yull FE, Li B, Cheng DS, Kernodle DS, Jansen ED, Contag CH, Segal BH, Holland SM, Blackwell TS, Christman JW. p47phox deficiency impairs NF-kappa B activation and host defense in Pseudomonas pneumonia. Journal of Immunology (Baltimore, Md. : 1950). 172: 1801-8. PMID 14734763 DOI: 10.4049/Jimmunol.172.3.1801  0.456
2004 Lee YC, Lane KB, Zoia O, Thompson PJ, Light RW, Blackwell TS. Transforming growth factor-beta induces collagen synthesis without inducing IL-8 production in mesothelial cells. The European Respiratory Journal. 22: 197-202. PMID 12952247 DOI: 10.1183/09031936.03.00086202  0.306
2003 Park GY, Joo M, Pedchenko T, Blackwell TS, Christman JW. Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L956-62. PMID 14672923 DOI: 10.1152/Ajplung.00338.2003  0.334
2003 Gray KD, Simovic MO, Chapman WC, Blackwell TS, Christman JW, May AK, Parman KS, Stain SC. Endotoxin potentiates lung injury in cerulein-induced pancreatitis. American Journal of Surgery. 186: 526-30. PMID 14599619 DOI: 10.1016/J.Amjsurg.2003.07.010  0.383
2003 Yull FE, Han W, Jansen ED, Everhart MB, Sadikot RT, Christman JW, Blackwell TS. Bioluminescent detection of endotoxin effects on HIV-1 LTR-driven transcription in vivo. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 51: 741-9. PMID 12754285 DOI: 10.1177/002215540305100605  0.796
2003 Gray KD, Simovic MO, Chapman WC, Blackwell TS, Christman JW, Washington MK, Yull FE, Jaffal N, Jansen ED, Gautman S, Stain SC. Systemic nf-kappaB activation in a transgenic mouse model of acute pancreatitis. The Journal of Surgical Research. 110: 310-4. PMID 12697416 DOI: 10.1016/S0022-4804(03)00024-6  0.441
2003 Maus UA, Waelsch K, Kuziel WA, Delbeck T, Mack M, Blackwell TS, Christman JW, Schlöndorff D, Seeger W, Lohmeyer J. Monocytes are potent facilitators of alveolar neutrophil emigration during lung inflammation: role of the CCL2-CCR2 axis. Journal of Immunology (Baltimore, Md. : 1950). 170: 3273-8. PMID 12626586 DOI: 10.4049/Jimmunol.170.6.3273  0.499
2003 Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS. Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation. Journal of Immunology (Baltimore, Md. : 1950). 170: 1091-8. PMID 12517978 DOI: 10.4049/Jimmunol.170.2.1091  0.821
2003 Gray KD, Simovic MO, Christman JW, Blackwell TS, May AK, Chapman WC, Stain SC. Pancreatitis-induced lung injury: mechanism of injury involves hepatic NF-KB and cytokine mediated pathways Journal of Surgical Research. 114: 292. DOI: 10.1016/J.Jss.2003.08.070  0.516
2002 Koay MA, Christman JW, Wudel LJ, Allos T, Cheng DS, Chapman WC, Blackwell TS. Modulation of endotoxin-induced NF-κB activation in lung and liver through TNF type 1 and IL-1 receptors American Journal of Physiology - Lung Cellular and Molecular Physiology. 283. PMID 12388356 DOI: 10.1152/Ajplung.00036.2002  0.462
2002 Maus UA, Koay MA, Delbeck T, Mack M, Ermert M, Ermert L, Blackwell TS, Christman JW, Schlöndorff D, Seeger W, Lohmeyer J. Role of resident alveolar macrophages in leukocyte traffic into the alveolar air space of intact mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L1245-52. PMID 12003780 DOI: 10.1152/Ajplung.00453.2001  0.532
2002 Sadikot RT, Wudel LJ, Jansen DE, Debelak JP, Yull FE, Christman JW, Blackwell TS, Chapman WC. Hepatic cryoablation-induced multisystem injury: bioluminescent detection of NF-kappaB activation in a transgenic mouse model. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 6: 264-70. PMID 11992813 DOI: 10.1016/S1091-255X(01)00064-6  0.461
2002 Koay MA, Gao X, Washington MK, Parman KS, Sadikot RT, Blackwell TS, Christman JW. Macrophages Are Necessary for Maximal Nuclear Factor- κ B Activation in Response to Endotoxin American Journal of Respiratory Cell and Molecular Biology. 26: 572-578. PMID 11970909 DOI: 10.1165/Ajrcmb.26.5.4748  0.535
2001 Koay MA, Christman JW, Segal BH, Venkatakrishnan A, Blackwell TR, Holland SM, Blackwell TS. Impaired pulmonary NF-kappaB activation in response to lipopolysaccharide in NADPH oxidase-deficient mice. Infection and Immunity. 69: 5991-6. PMID 11553535 DOI: 10.1128/Iai.69.10.5991-5996.2001  0.521
2001 Sadikot RT, Jansen ED, Blackwell TR, Zoia O, Yull F, Christman JW, Blackwell TS. High-dose dexamethasone accentuates nuclear factor-kappa b activation in endotoxin-treated mice. American Journal of Respiratory and Critical Care Medicine. 164: 873-8. PMID 11549548 DOI: 10.1164/Ajrccm.164.5.2008059  0.52
2001 Blackwell TS, Stecenko AA, Christman JW. Dysregulated NF-kappaB activation in cystic fibrosis: evidence for a primary inflammatory disorder. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L69-70. PMID 11404247 DOI: 10.1152/Ajplung.2001.281.1.L69  0.414
2001 Stecenko AA, King G, Torii K, Breyer RM, Dworski R, Blackwell TS, Christman JW, Brigham KL. Dysregulated cytokine production in human cystic fibrosis bronchial epithelial cells. Inflammation. 25: 145-55. PMID 11403205 DOI: 10.1023/A:1011080229374  0.311
2001 Blackwell TS, Christman JW. Defining the lung's response to endotoxin. American Journal of Respiratory and Critical Care Medicine. 163: 1516-7. PMID 11401864 DOI: 10.1164/Ajrccm.163.7.2103055D  0.392
2001 Lancaster LH, Christman JW, Blackwell TR, Koay MA, Blackwell TS. Suppression of lung inflammation in rats by prevention of NF-kappaB activation in the liver. Inflammation. 25: 25-31. PMID 11293663 DOI: 10.1023/A:1007071527408  0.412
2001 Cruz-Gervis RA, Stecenko AA, Blackwell TS, Sealy L, Loyd JE, King G, Brigham KL. Regulation of CCAAT/Enhancer-Binding Protein-β Is Altered in Primary Lung Fibroblasts Obtained From Patients With Idiopathic Pulmonary Fibrosis Chest. 120: S9. DOI: 10.1016/S0012-3692(15)38674-8  0.383
2000 Blackwell TS, Christman JW, Hagan T, Price P, Edens T, Morris PE, Wolff SN, Goodman SA, Christman BW. Oxidative stress and NF-kappaB activation: correlation in patients following allogeneic bone marrow transplantation. Antioxidants & Redox Signaling. 2: 93-102. PMID 11232605 DOI: 10.1089/Ars.2000.2.1-93  0.394
2000 Hao CM, Yull F, Blackwell T, Kömhoff M, Davis LS, Breyer MD. Dehydration activates an NF-kappaB-driven, COX2-dependent survival mechanism in renal medullary interstitial cells. The Journal of Clinical Investigation. 106: 973-82. PMID 11032857 DOI: 10.1172/Jci9956  0.372
2000 Blackwell TS, Yull FE, Chen CL, Venkatakrishnan A, Blackwell TR, Hicks DJ, Lancaster LH, Christman JW, Kerr LD. Multiorgan nuclear factor kappa B activation in a transgenic mouse model of systemic inflammation American Journal of Respiratory and Critical Care Medicine. 162: 1095-1101. PMID 10988136 DOI: 10.1164/Ajrccm.162.3.9906129  0.488
2000 Venkatakrishnan A, Stecenko AA, King G, Blackwell TR, Brigham KL, Christman JW, Blackwell TS. Exaggerated activation of nuclear factor-κB and altered IκB-β processing in cystic fibrosis bronchial epithelial cells American Journal of Respiratory Cell and Molecular Biology. 23: 396-403. PMID 10970832 DOI: 10.1165/Ajrcmb.23.3.3949  0.425
2000 Chapman WC, Debelak JP, Blackwell TS, Gainer KA, Christman JW, Pinson CW, Brigham KL, Parker RE. Hepatic cryoablation-induced acute lung injury: Pulmonary hemodynamic and permeability effects in a sheep model Archives of Surgery. 135: 667-673. PMID 10843362 DOI: 10.1001/Archsurg.135.6.667  0.414
2000 Christman JW, Sadikot RT, Blackwell TS. The Role of Nuclear Factor-κ B in Pulmonary Diseases Chest. 117: 1482-1487. PMID 10807839 DOI: 10.1378/Chest.117.5.1482  0.326
2000 Chapman WC, Debelak JP, Wright Pinson C, Washington MK, Atkinson JB, Venkatakrishnan A, Blackwell TS, Christman JW. Hepatic cryoablation, but not radiofrequency ablation, results in lung inflammation. Annals of Surgery. 231: 752-61. PMID 10767797 DOI: 10.1097/00000658-200005000-00016  0.49
2000 Christman JW, Blackwell TS, Juurlink BH. Redox regulation of nuclear factor kappa B: therapeutic potential for attenuating inflammatory responses. Brain Pathology (Zurich, Switzerland). 10: 153-62. PMID 10668905 DOI: 10.1111/J.1750-3639.2000.Tb00252.X  0.392
2000 Christman JW, Venkatakrishnan A, Wheeler AP, Bernard GR, Blackwell TS. NF-κB binding activity in mixed bal cells from patients with SIRS and ARDS Sepsis. 4: 35-41. DOI: 10.1023/A:1009848917526  0.431
1999 Blackwell TS, Lancaster LH, Blackwell TR, Venkatakrishnan A, Christman JW. Differential NF-κB activation after intratracheal endotoxin. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L823-L830. PMID 29592130 DOI: 10.1152/ajplung.1999.277.4.L823  0.377
1999 Blackwell TS, Lancaster LH, Blackwell TR, Venkatakrishnan A, Christman JW. Differential NF-κB activation after intratracheal endotoxin American Journal of Physiology - Lung Cellular and Molecular Physiology. 277: L823-L830. PMID 10516225 DOI: 10.1152/Ajplung.1999.277.4.L823  0.478
1999 Blackwell TS, Debelak JP, Venkatakrishnan A, Schot DJ, Harley DH, Pinson CW, Williams P, Washington K, Christman JW, Chapman WC. Acute lung injury after hepatic cryoablation: Correlation with NF-κB activation and cytokine production Surgery. 126: 518-526. PMID 10486604 DOI: 10.1016/S0039-6060(99)70093-0  0.459
1999 Blackwell TS, Yull FE, Chen CL, Venkatakrishnan A, Blackwell TR, Hicks DJ, Lancaster LH, Christman JW, Kerr LD. Use of genetically altered mice to investigate the role of nuclear factor-kappa B activation and cytokine gene expression in sepsis-induced ARDS Chest. 116: 73S-74S. PMID 10424600 DOI: 10.1378/Chest.116.Suppl_1.73S  0.39
1999 Blackwell TS, Lancaster LH, Blackwell TR, Venkatakrishnan A, Christman JW. Chemotactic gradients predict neutrophilic alveolitis in endotoxin- treated rats American Journal of Respiratory and Critical Care Medicine. 159: 1644-1652. PMID 10228139 DOI: 10.1164/Ajrccm.159.5.9806166  0.389
1999 Christman JW, Lancaster LH, Blackwell TS. Nuclear factor kappa B: a pivotal role in the systemic inflammatory response syndrome and new target for therapy. Intensive Care Medicine. 24: 1131-8. PMID 9876974 DOI: 10.1007/S001340050735  0.44
1998 Debelak J, Schot D, Blackwell T, Christman J, Pinson C, Williams P, Washington K, Chapman W. Hepatic cryoablation induces NF-kB activation, cytokine production, and lung injury in a rat model Gastroenterology. 114: A1232. DOI: 10.1016/S0016-5085(98)84999-8  0.319
1997 Blackwell TS, Blackwell TR, Christman JW. Induction of endotoxin tolerance depletes nuclear factor-kappaB and suppresses its activation in rat alveolar macrophages. Journal of Leukocyte Biology. 62: 885-91. PMID 9400831 DOI: 10.1002/Jlb.62.6.885  0.47
1997 Blackwell TS, Christman JW. The role of nuclear factor-kappa B in cytokine gene regulation. American Journal of Respiratory Cell and Molecular Biology. 17: 3-9. PMID 9224203 DOI: 10.1165/Ajrcmb.17.1.F132  0.395
1996 Blackwell TS, Christman JW. Sepsis and cytokines: current status. British Journal of Anaesthesia. 77: 110-7. PMID 8703620 DOI: 10.1093/Bja/77.1.110  0.341
1994 Blackwell TS, Holden EP, Blackwell TR, DeLarco JE, Christman JW. Cytokine-induced neutrophil chemoattractant mediates neutrophilic alveolitis in rats: association with nuclear factor kappa B activation. American Journal of Respiratory Cell and Molecular Biology. 11: 464-72. PMID 7917314 DOI: 10.1165/Ajrcmb.11.4.7917314  0.459
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