| Year |
Citation |
Score |
| 2024 |
Lai J, Yang C, Shang C, Chen W, Chu MP, Brandwein J, Lai R, Wang P. ULK2 Is a Key Pro-Autophagy Protein That Contributes to the High Chemoresistance and Disease Relapse in FLT3-Mutated Acute Myeloid Leukemia. International Journal of Molecular Sciences. 25. PMID 38203816 DOI: 10.3390/ijms25010646 |
0.391 |
|
| 2023 |
Lai J, Shang C, Chen W, Izevbaye I, Chu MP, Sandhu I, Brandwein J, Lai R, Wang P. An In Vitro Model for Acute Myeloid Leukemia Relapse Using the SORE6 Reporter. International Journal of Molecular Sciences. 25. PMID 38203669 DOI: 10.3390/ijms25010496 |
0.39 |
|
| 2023 |
Shang C, Lai J, Haque M, Chen W, Wang P, Lai R. Nuclear NPM-ALK Protects Myc from Proteasomal Degradation and Contributes to Its High Expression in Cancer Stem-Like Cells in ALK-Positive Anaplastic Large Cell Lymphoma. International Journal of Molecular Sciences. 24. PMID 37762644 DOI: 10.3390/ijms241814337 |
0.356 |
|
| 2022 |
Jafari S, Heydarian S, Lai R, Mehdizadeh Aghdam E, Molavi O. Silibinin induces immunogenic cell death in cancer cells and enhances the induced immunogenicity by chemotherapy. Bioimpacts : Bi. 13: 51-61. PMID 36816998 DOI: 10.34172/bi.2022.23698 |
0.309 |
|
| 2021 |
Garland GD, Ducray SP, Jahangiri L, Pucci P, Amos Burke GA, Monahan J, Lai R, Merkel O, Schiefer AI, Kenner L, Bannister AJ, Turner SD. BRG1 and NPM-ALK Are Co-Regulated in Anaplastic Large-Cell Lymphoma; BRG1 Is a Potential Therapeutic Target in ALCL. Cancers. 14. PMID 35008316 DOI: 10.3390/cancers14010151 |
0.426 |
|
| 2021 |
Li J, Haque M, Shang C, Hassan B, Liu D, Chen W, Lai R. Identification and Characterization of Cancer Stem-Like Cells in ALK-Positive Anaplastic Large Cell Lymphoma Using the SORE6 Reporter. Current Issues in Molecular Biology. 43: 543-557. PMID 34287231 DOI: 10.3390/cimb43020041 |
0.383 |
|
| 2021 |
Alshareef A, Peters AC, Gélébart P, Chen W, Lai R. Gene Methylation and Silencing of WIF1 Is a Frequent Genetic Abnormality in Mantle Cell Lymphoma. International Journal of Molecular Sciences. 22. PMID 33477402 DOI: 10.3390/ijms22020893 |
0.35 |
|
| 2021 |
Shang C, Hassan B, Haque M, Song Y, Li J, Liu D, Lipke E, Chen W, Giuriato S, Lai R. Crizotinib Resistance Mediated by Autophagy Is Higher in the Stem-Like Cell Subset in ALK-Positive Anaplastic Large Cell Lymphoma, and This Effect Is MYC-Dependent. Cancers. 13. PMID 33430343 DOI: 10.3390/cancers13020181 |
0.346 |
|
| 2019 |
Haque M, Li J, Huang YH, Almowaled M, Barger CJ, Karpf AR, Wang P, Chen W, Turner SD, Lai R. NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma. Cancers. 11. PMID 31390744 DOI: 10.3390/Cancers11081119 |
0.537 |
|
| 2019 |
Mackey JR, Beauchamp E, Yap MC, Iyer A, Perinpanayagam MA, Vincent KM, Al-Momany AM, Heit RJ, Sim JY, Lai R, Dong W, Lakshmanan M, Raju A, Tergaonkar V, Tan SY, et al. Abstract 3046: Targeting N-myristoylation in B cell lymphomas as a therapeutic strategy Cancer Research. 79: 3046-3046. DOI: 10.1158/1538-7445.Am2019-3046 |
0.476 |
|
| 2018 |
Soleymani Abyaneh H, Gupta N, Alshareef A, Gopal K, Lavasanifar A, Lai R. Hypoxia Induces the Acquisition of Cancer Stem-like Phenotype Via Upregulation and Activation of Signal Transducer and Activator of Transcription-3 (STAT3) in MDA-MB-231, a Triple Negative Breast Cancer Cell Line. Cancer Microenvironment : Official Journal of the International Cancer Microenvironment Society. PMID 30255421 DOI: 10.1007/S12307-018-0218-0 |
0.458 |
|
| 2018 |
Bigras G, Mairs S, Swanson PE, Morel D, Lai R, Izevbaye I. Small Biopsies Misclassify up to 35% of PD-L1 Assessments in Advanced Lung Non-Small Cell Lung Carcinomas. Applied Immunohistochemistry & Molecular Morphology : Aimm. PMID 30095468 DOI: 10.1097/Pai.0000000000000698 |
0.31 |
|
| 2018 |
Siegers GM, Dutta I, Lai R, Postovit LM. Functional Plasticity of Gamma Delta T Cells and Breast Tumor Targets in Hypoxia. Frontiers in Immunology. 9: 1367. PMID 29963058 DOI: 10.3389/Fimmu.2018.01367 |
0.395 |
|
| 2018 |
Huang YH, Molavi O, Alshareef A, Haque M, Wang Q, Chu MP, Venner CP, Sandhu I, Peters AC, Lavasanifar A, Lai R. Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model. Cancers. 10. PMID 29914181 DOI: 10.3390/Cancers10060206 |
0.326 |
|
| 2018 |
Zhang Y, Chen Y, Liu Z, Lai R. ERK is a negative feedback regulator for IFN-γ/STAT1 signaling by promoting STAT1 ubiquitination. Bmc Cancer. 18: 613. PMID 29855346 DOI: 10.1186/S12885-018-4539-7 |
0.392 |
|
| 2018 |
Wu C, Gupta N, Huang YH, Zhang HF, Alshareef A, Chow A, Lai R. Oxidative stress enhances tumorigenicity and stem-like features via the activation of the Wnt/β-catenin/MYC/Sox2 axis in ALK-positive anaplastic large-cell lymphoma. Bmc Cancer. 18: 361. PMID 29609590 DOI: 10.1186/S12885-018-4300-2 |
0.444 |
|
| 2018 |
Alshareef A, Irwin MS, Gupta N, Zhang HF, Haque M, Findlay SD, Seong BKA, Lai J, Rayis M, Al-Dandan S, Lai R. The absence of a novel intron 19-retainingtranscript (-I19) andamplification correlates with an excellent clinical outcome in neuroblastoma patients. Oncotarget. 9: 10698-10713. PMID 29535836 DOI: 10.18632/Oncotarget.24216 |
0.432 |
|
| 2018 |
Gupta N, Gopal K, Wu C, Alshareef A, Chow A, Wu F, Wang P, Ye X, Bigras G, Lai R. Phosphorylation of Sox2 at Threonine 116 is a Potential Marker to Identify a Subset of Breast Cancer Cells with High Tumorigenecity and Stem-Like Features. Cancers. 10. PMID 29401647 DOI: 10.3390/Cancers10020041 |
0.379 |
|
| 2017 |
Alshareef A, Gupta N, Zhang HF, Wu C, Haque M, Lai R. High expression of β-catenin contributes to the crizotinib resistant phenotype in the stem-like cell population in neuroblastoma. Scientific Reports. 7: 16863. PMID 29203817 DOI: 10.1038/S41598-017-17319-9 |
0.414 |
|
| 2017 |
Soleymani Abyaneh H, Gupta N, Radziwon-Balicka A, Jurasz P, Seubert J, Lai R, Lavasanifar A. STAT3 but Not HIF-1α Is Important in Mediating Hypoxia-Induced Chemoresistance in MDA-MB-231, a Triple Negative Breast Cancer Cell Line. Cancers. 9. PMID 29036915 DOI: 10.3390/Cancers9100137 |
0.39 |
|
| 2017 |
Zhang Y, Chen Y, Yun H, Liu Z, Su M, Lai R. STAT1β enhances STAT1 function by protecting STAT1α from degradation in esophageal squamous cell carcinoma. Cell Death & Disease. 8: e3077. PMID 28981100 DOI: 10.1038/Cddis.2017.481 |
0.438 |
|
| 2017 |
Gupta N, Jung K, Wu C, Alshareef A, Alqahtani H, Damaraju S, Mackey JR, Ghosh S, Sabri S, Abdulkarim BS, Bigras G, Lai R. High Myc expression and transcription activity underlies intra-tumoral heterogeneity in triple-negative breast cancer. Oncotarget. PMID 28427212 DOI: 10.18632/Oncotarget.15891 |
0.498 |
|
| 2017 |
Soleimani AH, Garg SM, Paiva IM, Vakili MR, Alshareef A, Huang YH, Molavi O, Lai R, Lavasanifar A. Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma. Drug Delivery and Translational Research. PMID 28290050 DOI: 10.1007/S13346-017-0369-4 |
0.304 |
|
| 2017 |
Molavi O, Narimani F, Asiaee F, Sharifi S, Tarhriz V, Shayanfar A, Hejazi M, Lai R. Silibinin sensitizes chemo-resistant breast cancer cells to chemotherapy. Pharmaceutical Biology. 55: 729-739. PMID 28027688 DOI: 10.1080/13880209.2016.1270972 |
0.309 |
|
| 2016 |
Wu C, Zhang HF, Gupta N, Alshareef A, Wang Q, Huang YH, Lewis JT, Douglas DN, Kneteman NM, Lai R. A positive feedback loop involving the Wnt/β-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma. Journal of Hematology & Oncology. 9: 120. PMID 27821172 DOI: 10.1186/S13045-016-0349-Z |
0.462 |
|
| 2016 |
Lopez-Campistrous A, Adewuyi EE, Benesch MG, Ko YM, Lai R, Thiesen A, Dewald J, Wang P, Chu K, Ghosh S, Williams DC, Vos LJ, Brindley DN, McMullen TP. PDGFRα Regulates Follicular Cell Differentiation Driving Treatment Resistance and Disease Recurrence in Papillary Thyroid Cancer. Ebiomedicine. PMID 27682510 DOI: 10.1016/J.Ebiom.2016.09.007 |
0.39 |
|
| 2016 |
Alshareef A, Zhang HF, Huang YH, Wu C, Zhang JD, Wang P, El-Sehemy A, Fares M, Lai R. The use of cellular thermal shift assay (CETSA) to study Crizotinib resistance in ALK-expressing human cancers. Scientific Reports. 6: 33710. PMID 27641368 DOI: 10.1038/Srep33710 |
0.367 |
|
| 2016 |
Zhang HF, Alshareef A, Wu C, Jiao JW, Sorensen PH, Lai R, Xu LY, Li EM. miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma. Carcinogenesis. PMID 27496804 DOI: 10.1093/Carcin/Bgw079 |
0.333 |
|
| 2016 |
Zhang HF, Wu C, Alshareef A, Gupta N, Zhao Q, Xu XE, Jiao JW, Li EM, Xu LY, Lai R. The PI3K/AKT/c-MYC axis promotes the acquisition of cancer stem-like features in esophageal squamous cell carcinoma. Stem Cells (Dayton, Ohio). PMID 27144349 DOI: 10.1002/Stem.2395 |
0.448 |
|
| 2016 |
Stubbins RJ, Zhu J, Lai R, Owen CJ, Preiksaitis J, Peters AC. CD3 T-Cell Infiltrates at Diagnosis Predicts Overall Survival in Solid Organ Transplant Recipients with Post-Transplant Lymphoproliferative Disorders (PTLD) Blood. 128: 1873-1873. DOI: 10.1182/Blood.V128.22.1873.1873 |
0.307 |
|
| 2016 |
Wu C, Zhang H, Gupta N, Abdulraheem A, Wang Q, Huang Y, Lai R. Abstract 3335: The high cMyc expression characterizes a small cell subpopulation in ALK-positive anaplastic large cell lymphoma that carry cancer stem-like properties Cancer Research. 76: 3335-3335. DOI: 10.1158/1538-7445.Am2016-3335 |
0.526 |
|
| 2015 |
Gopal K, Gupta N, Zhang H, Alshareef A, Alqahtani H, Bigras G, Lewis J, Douglas D, Kneteman N, Lavasanifar A, Lai R. Oxidative stress induces the acquisition of cancer stem-like phenotype in breast cancer detectable by using a Sox2 regulatory region-2 (SRR2) reporter. Oncotarget. PMID 26683522 DOI: 10.18632/Oncotarget.6630 |
0.395 |
|
| 2015 |
Alqahtani H, Gopal K, Gupta N, Jung K, Alshareef A, Ye X, Wu F, Li L, Lai R. DDX17 (P72), a Sox2 binding partner, promotes stem-like features conferred by Sox2 in a small cell population in estrogen receptor-positive breast cancer. Cellular Signalling. PMID 26569340 DOI: 10.1016/J.Cellsig.2015.11.004 |
0.442 |
|
| 2015 |
Zhang HF, Chen Y, Wu C, Wu Z, Tweardy DJ, Alshareef A, Liao LD, Xue YJ, Wu JY, Chen B, Xu XE, Gopal K, Gupta N, Li EM, Xu LY, ... Lai R, et al. The opposing function of STAT3 as an oncoprotein and tumor suppressor is dictated by the expression status of STAT3β in esophageal squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26405196 DOI: 10.1158/1078-0432.Ccr-15-1253 |
0.38 |
|
| 2015 |
Zhang HF, Alshareef A, Wu C, Li S, Jiao JW, Cao HH, Lai R, Xu LY, Li EM. Loss of miR-200b promotes invasion via activating the Kindlin-2/integrin β1/AKT pathway in esophageal squamous cell carcinoma: An E-cadherin-independent mechanism. Oncotarget. PMID 26334393 DOI: 10.18632/Oncotarget.5027 |
0.326 |
|
| 2015 |
Molavi O, Samadi N, Wu C, Lavasanifar A, Lai R. Silibinin suppresses NPM-ALK, potently induces apoptosis and enhances chemosensitivity in ALK-positive anaplastic large cell lymphoma. Leukemia & Lymphoma. 1-27. PMID 26133723 DOI: 10.3109/10428194.2015.1068306 |
0.517 |
|
| 2015 |
Benesch MG, Ko YM, Tang X, Dewald J, Lopez-Campistrous A, Zhao YY, Lai R, Curtis JM, Brindley DN, McMullen TP. Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer. Endocrine-Related Cancer. 22: 593-607. PMID 26037280 DOI: 10.1530/Erc-15-0045 |
0.313 |
|
| 2015 |
Bone KM, Wang P, Wu F, Wu C, Li L, Bacani JT, Andrew SE, Lai R. NPM-ALK mediates phosphorylation of MSH2 at tyrosine 238, creating a functional deficiency in MSH2 and the loss of mismatch repair. Blood Cancer Journal. 5: e311. PMID 25978431 DOI: 10.1038/Bcj.2015.35 |
0.46 |
|
| 2015 |
Wu C, Molavi O, Zhang H, Gupta N, Alshareef A, Bone KM, Gopal K, Wu F, Lewis JT, Douglas DN, Kneteman NM, Lai R. STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma. Blood. 126: 336-45. PMID 25921060 DOI: 10.1182/Blood-2014-10-603738 |
0.475 |
|
| 2015 |
Jung K, Gupta N, Wang P, Lewis JT, Gopal K, Wu F, Ye X, Alshareef A, Abdulkarim BS, Douglas DN, Kneteman NM, Lai R. Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter. Oncotarget. 6: 10366-73. PMID 25868977 DOI: 10.18632/Oncotarget.3590 |
0.446 |
|
| 2014 |
Zhang Y, Zhang Y, Yun H, Lai R, Su M. Correlation of STAT1 with apoptosis and cell-cycle markers in esophageal squamous cell carcinoma. Plos One. 9: e113928. PMID 25438156 DOI: 10.1371/Journal.Pone.0113928 |
0.417 |
|
| 2014 |
Jung K, Wang P, Gupta N, Gopal K, Wu F, Ye X, Alshareef A, Bigras G, McMullen TP, Abdulkarim BS, Lai R. Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays. Breast Cancer Research : Bcr. 16: 470. PMID 25380620 DOI: 10.1186/S13058-014-0470-2 |
0.419 |
|
| 2014 |
Zhang Y, Molavi O, Su M, Lai R. The clinical and biological significance of STAT1 in esophageal squamous cell carcinoma. Bmc Cancer. 14: 791. PMID 25355139 DOI: 10.1186/1471-2407-14-791 |
0.355 |
|
| 2014 |
Yim RL, Wong KY, Kwong YL, Loong F, Leung CY, Chu R, Lam WW, Hui PK, Lai R, Chim CS. Methylation of miR-155-3p in mantle cell lymphoma and other non-Hodgkin's lymphomas. Oncotarget. 5: 9770-82. PMID 25211095 DOI: 10.18632/Oncotarget.2390 |
0.31 |
|
| 2014 |
Zhang HF, Lai R. STAT3 in Cancer-Friend or Foe? Cancers. 6: 1408-40. PMID 24995504 DOI: 10.3390/Cancers6031408 |
0.39 |
|
| 2014 |
Jung K, Wu F, Wang P, Ye X, Abdulkarim BS, Lai R. YB-1 regulates Sox2 to coordinately sustain stemness and tumorigenic properties in a phenotypically distinct subset of breast cancer cells. Bmc Cancer. 14: 328. PMID 24885403 DOI: 10.1186/1471-2407-14-328 |
0.358 |
|
| 2014 |
Han M, Vakili MR, Soleymani Abyaneh H, Molavi O, Lai R, Lavasanifar A. Mitochondrial delivery of doxorubicin via triphenylphosphine modification for overcoming drug resistance in MDA-MB-435/DOX cells. Molecular Pharmaceutics. 11: 2640-9. PMID 24811541 DOI: 10.1021/Mp500038G |
0.365 |
|
| 2014 |
Ye X, Wu F, Wu C, Wang P, Jung K, Gopal K, Ma Y, Li L, Lai R. β-Catenin, a Sox2 binding partner, regulates the DNA binding and transcriptional activity of Sox2 in breast cancer cells Cellular Signalling. 26: 492-501. PMID 24291232 DOI: 10.1016/J.Cellsig.2013.11.023 |
0.459 |
|
| 2014 |
Zhang HF, Zhang K, Liao LD, Li LY, Du ZP, Wu BL, Wu JY, Xu XE, Zeng FM, Chen B, Cao HH, Zhu MX, Dai LH, Long L, Wu ZY, ... Lai R, et al. miR-200b suppresses invasiveness and modulates the cytoskeletal and adhesive machinery in esophageal squamous cell carcinoma cells via targeting Kindlin-2. Carcinogenesis. 35: 292-301. PMID 24064224 DOI: 10.1093/Carcin/Bgt320 |
0.315 |
|
| 2014 |
North S, El-Gehani F, Santos C, Ghosh S, Lai R, Cass CE, Mackey JR. Expression of nucleoside transporters and deoxycytidine kinase proteins in muscle invasive urothelial carcinoma of the bladder: correlation with pathological response to neoadjuvant platinum/gemcitabine combination chemotherapy. The Journal of Urology. 191: 35-9. PMID 23851183 DOI: 10.1016/J.Juro.2013.07.006 |
0.347 |
|
| 2014 |
Zhang H, Lai R, Li E, Xu L. Abstract 3507: STAT3beta suppresses tumorigenesis via modulating the phosphorylation dynamics and transcription activity of STAT3alpha in esophageal squamous cell carcinoma Cancer Research. 74: 3507-3507. DOI: 10.1158/1538-7445.Am2014-3507 |
0.447 |
|
| 2013 |
Molavi O, Xiong XB, Douglas D, Kneteman N, Nagata S, Pastan I, Chu Q, Lavasanifar A, Lai R. Anti-CD30 antibody conjugated liposomal doxorubicin with significantly improved therapeutic efficacy against anaplastic large cell lymphoma. Biomaterials. 34: 8718-25. PMID 23942212 DOI: 10.1016/J.Biomaterials.2013.07.068 |
0.325 |
|
| 2013 |
Tang Y, Mackey J, Lai R, Ghosh S, Santos C, Graham K, Damaraju S, Pasdar M, Li L. Quantitative proteomic analysis of HER2 normal and overexpressing MCF-7 breast cancer cells revealed proteomic changes accompanied with HER2 gene amplification. Journal of Proteomics. 91: 200-9. PMID 23851309 DOI: 10.1016/J.Jprot.2013.06.034 |
0.379 |
|
| 2013 |
Goswami RS, Atenafu EG, Xuan Y, Waldron L, Reis PP, Sun T, Datti A, Xu W, Kuruvilla J, Good DJ, Lai R, Church AJ, Lam WS, Baetz T, Lebrun DP, et al. MicroRNA signature obtained from the comparison of aggressive with indolent non-Hodgkin lymphomas: potential prognostic value in mantle-cell lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2903-11. PMID 23835716 DOI: 10.1200/Jco.2012.45.3050 |
0.35 |
|
| 2013 |
Wu F, Ye X, Wang P, Jung K, Wu C, Douglas D, Kneteman N, Bigras G, Ma Y, Lai R. Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity. Bmc Cancer. 13: 317. PMID 23815808 DOI: 10.1186/1471-2407-13-317 |
0.378 |
|
| 2013 |
Molavi O, Wang P, Zak Z, Gelebart P, Belch A, Lai R. Gene methylation and silencing of SOCS3 in mantle cell lymphoma. British Journal of Haematology. 161: 348-56. PMID 23432547 DOI: 10.1111/Bjh.12262 |
0.457 |
|
| 2013 |
Sapkota Y, Ghosh S, Lai R, Coe BP, Cass CE, Yasui Y, Mackey JR, Damaraju S. Germline DNA copy number aberrations identified as potential prognostic factors for breast cancer recurrence. Plos One. 8: e53850. PMID 23342018 DOI: 10.1371/Journal.Pone.0053850 |
0.319 |
|
| 2013 |
Armanious H, Gelebart P, Anand M, Lai R. Identification of a novel crosstalk between casein kinase 2α and NPM-ALK in ALK-positive anaplastic large cell lymphoma. Cellular Signalling. 25: 381-8. PMID 23153582 DOI: 10.1016/J.Cellsig.2012.11.005 |
0.455 |
|
| 2013 |
Hegazy SA, Alshareef A, Gelebart P, Anand M, Armanious H, Ingham RJ, Lai R. Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma. Cellular Signalling. 25: 295-307. PMID 23022960 DOI: 10.1016/J.Cellsig.2012.09.027 |
0.793 |
|
| 2013 |
Hegazy SA, Alshareef A, Gelebart P, Anand M, Armanious H, Ingham RJ, Lai R. Corrigendum to "Disheveled proteins promote cell growth and tumorigenicity in ALK-positive anaplastic large cell lymphoma" [Cell. Signal. 2013; 25:295-307] Cellular Signalling. 25: 580. DOI: 10.1016/J.Cellsig.2012.11.013 |
0.785 |
|
| 2012 |
Mereniuk TR, Maranchuk RA, Schindler A, Penner-Chea J, Freschauf GK, Hegazy S, Lai R, Foley E, Weinfeld M. Genetic screening for synthetic lethal partners of polynucleotide kinase/phosphatase: potential for targeting SHP-1-depleted cancers. Cancer Research. 72: 5934-44. PMID 22962271 DOI: 10.1158/0008-5472.Can-12-0939 |
0.77 |
|
| 2012 |
Gelebart P, Hegazy SA, Wang P, Bone KM, Anand M, Sharon D, Hitt M, Pearson JD, Ingham RJ, Ma Y, Lai R. Aberrant expression and biological significance of Sox2, an embryonic stem cell transcriptional factor, in ALK-positive anaplastic large cell lymphoma. Blood Cancer Journal. 2: e82. PMID 22885405 DOI: 10.1038/Bcj.2012.27 |
0.802 |
|
| 2012 |
Pearson JD, Lee JK, Bacani JT, Lai R, Ingham RJ. NPM-ALK: The Prototypic Member of a Family of Oncogenic Fusion Tyrosine Kinases. Journal of Signal Transduction. 2012: 123253. PMID 22852078 DOI: 10.1155/2012/123253 |
0.445 |
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| 2012 |
Wu F, Zhang J, Wang P, Ye X, Jung K, Bone KM, Pearson JD, Ingham RJ, McMullen TP, Ma Y, Lai R. Identification of two novel phenotypically distinct breast cancer cell subsets based on Sox2 transcription activity. Cellular Signalling. 24: 1989-98. PMID 22800865 DOI: 10.1016/J.Cellsig.2012.07.008 |
0.476 |
|
| 2012 |
Zhang J, Wang P, Dykstra M, Gelebart P, Williams D, Ingham R, Adewuyi EE, Lai R, McMullen T. Platelet-derived growth factor receptor-α promotes lymphatic metastases in papillary thyroid cancer Journal of Pathology. 228: 241-250. PMID 22744707 DOI: 10.1002/Path.4069 |
0.336 |
|
| 2012 |
Wang P, Zhang JD, Wu F, Ye X, Sharon D, Hitt M, McMullen TP, Hegazy SA, Gelebart P, Yang J, Ma Y, Lai R. The expression and oncogenic effects of the embryonic stem cell marker SALL4 in ALK-positive anaplastic large cell lymphoma. Cellular Signalling. 24: 1955-63. PMID 22743134 DOI: 10.1016/J.Cellsig.2012.06.005 |
0.799 |
|
| 2012 |
Pearson JD, Mohammed Z, Bacani JT, Lai R, Ingham RJ. The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein. Bmc Cancer. 12: 229. PMID 22681779 DOI: 10.1186/1471-2407-12-229 |
0.444 |
|
| 2012 |
Zhang J, Gill AJ, Issacs JD, Atmore B, Johns A, Delbridge LW, Lai R, McMullen TP. The Wnt/β-catenin pathway drives increased cyclin D1 levels in lymph node metastasis in papillary thyroid cancer. Human Pathology. 43: 1044-50. PMID 22204713 DOI: 10.1016/J.Humpath.2011.08.013 |
0.312 |
|
| 2012 |
Zhang J, Wang P, Wu F, Li M, Sharon D, Ingham RJ, Hitt M, McMullen TP, Lai R. Aberrant expression of the transcriptional factor Twist1 promotes invasiveness in ALK-positive anaplastic large cell lymphoma. Cellular Signalling. 24: 852-8. PMID 22155737 DOI: 10.1016/j.cellsig.2011.11.020 |
0.419 |
|
| 2012 |
Borbath I, Verbrugghe L, Lai R, Gigot J, Humblet Y, Piessevaux H, Sempoux C. Human equilibrative nucleoside transporter 1 (hENT1) expression is a potential predictive tool for response to gemcitabine in patients with advanced cholangiocarcinoma. European Journal of Cancer. 48: 990-996. PMID 22137164 DOI: 10.1016/J.Ejca.2011.11.006 |
0.338 |
|
| 2012 |
Wilson WH, Jung SH, Porcu P, Hurd D, Johnson J, Martin SE, Czuczman M, Lai R, Said J, Chadburn A, Jones D, Dunleavy K, Canellos G, Zelenetz AD, Cheson BD, et al. A Cancer and Leukemia Group B multi-center study of DA-EPOCH-rituximab in untreated diffuse large B-cell lymphoma with analysis of outcome by molecular subtype. Haematologica. 97: 758-65. PMID 22133772 DOI: 10.3324/Haematol.2011.056531 |
0.332 |
|
| 2012 |
Reiman T, Lai R, Veillard AS, Paris E, Soria JC, Rosell R, Taron M, Graziano S, Kratzke R, Seymour L, Shepherd FA, Pignon JP, Sève P. Cross-validation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: Analysis of four randomized trials Annals of Oncology. 23: 86-93. PMID 21471564 DOI: 10.1093/Annonc/Mdr033 |
0.349 |
|
| 2012 |
Goswami RS, Xuan Y, Waldron L, Sukhai MA, Reis PP, Sun T, Datti A, Xu W, Kuruvilla J, Good D, Lai R, Lam W, Church A, LeBrun D, Sehn LH, et al. A 7-Gene Microrna Signature Characteristic of Mantle Cell Lymphoma Reveals Focal Adhesion and Integrin Signalling, Proteasome-Mediated Degradation, and the PI3K Signalling Cascade As Important to MCL Pathogenesis Blood. 120: 1586-1586. DOI: 10.1182/Blood.V120.21.1586.1586 |
0.338 |
|
| 2012 |
Goswami RS, Atenafu EG, Waldron L, Xuan Y, Xu W, Reis PP, Kuruvilla J, Good DJ, Bailey DJ, Lai R, Church A, Lam WS, LeBrun DP, Sehn LH, Farinha P, et al. Identification of a Novel Prognostic microRNA Signature in Mantle Cell Lymphoma Laboratory Investigation. DOI: 10.1038/Labinvest.2012.38 |
0.412 |
|
| 2012 |
Farrell JJ, Moughan J, Wong JL, Regine WF, Scaefer P, Benson AB, Macdonald JS, Liu X, Yen Y, Lai R, Zheng Z, Bepler G, Guha C, Elsaleh H. 559 Predictive Markers of Gemcitabine Treatment Response in Pancreas Cancer: A Pharmacogenomic Pathway Approach Gastroenterology. 142: S-113. DOI: 10.1016/S0016-5085(12)60424-7 |
0.309 |
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| 2011 |
Yang J, Aguila JR, Alipio Z, Lai R, Fink LM, Ma Y. Enhanced self-renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene Sall4. Journal of Hematology & Oncology. 4: 38. PMID 21943195 DOI: 10.1186/1756-8722-4-38 |
0.331 |
|
| 2011 |
Evans RP, Dueck G, Sidhu R, Ghosh S, Toman I, Loree J, Bahlis N, Klimowicz AC, Fung J, Jung M, Lai R, Pilarski LM, Belch AR, Reiman T. Expression, adverse prognostic significance and therapeutic small molecule inhibition of Polo-like kinase 1 in multiple myeloma. Leukemia Research. 35: 1637-43. PMID 21816470 DOI: 10.1016/j.leukres.2011.07.016 |
0.322 |
|
| 2011 |
Young LC, Bone KM, Wang P, Wu F, Adam BA, Hegazy S, Gelebart P, Holovati J, Li L, Andrew SE, Lai R. Fusion tyrosine kinase NPM-ALK deregulates MSH2 and suppresses DNA mismatch repair function: Novel insights into a potent oncoprotein American Journal of Pathology. 179: 411-421. PMID 21703420 DOI: 10.1016/J.Ajpath.2011.03.045 |
0.778 |
|
| 2011 |
Armanious H, Gelebart P, Anand M, Belch A, Lai R. Constitutive activation of metalloproteinase ADAM10 in mantle cell lymphoma promotes cell growth and activates the TNFα/NFκB pathway. Blood. 117: 6237-46. PMID 21441465 DOI: 10.1182/Blood-2010-10-313940 |
0.479 |
|
| 2011 |
Toman I, Loree J, Klimowicz AC, Bahlis N, Lai R, Belch A, Pilarski L, Reiman T. Expression and prognostic significance of Oct2 and Bob1 in multiple myeloma: implications for targeted therapeutics. Leukemia & Lymphoma. 52: 659-67. PMID 21438833 DOI: 10.3109/10428194.2010.548535 |
0.384 |
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| 2011 |
Pearson JD, Lee JK, Bacani JT, Lai R, Ingham RJ. NPM-ALK and the JunB transcription factor regulate the expression of cytotoxic molecules in ALK-positive, anaplastic large cell lymphoma. International Journal of Clinical and Experimental Pathology. 4: 124-33. PMID 21326808 |
0.382 |
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| 2011 |
Gelebart P, Zak Z, Dien-Bard J, Anand M, Lai R. Interleukin 22 signaling promotes cell growth in mantle cell lymphoma. Translational Oncology. 4: 9-19. PMID 21286373 DOI: 10.1593/Tlo.10172 |
0.366 |
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| 2011 |
Wang P, Wu F, Zhang J, McMullen T, Young LC, Ingham RJ, Li L, Lai R. Serine phosphorylation of NPM-ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential Carcinogenesis. 32: 146-153. PMID 21045017 DOI: 10.1093/Carcin/Bgq229 |
0.372 |
|
| 2011 |
Anand M, Lai R, Gelebart P. β-catenin is constitutively active and increases STAT3 expression/activation in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Haematologica. 96: 253-61. PMID 20971814 DOI: 10.3324/Haematol.2010.027086 |
0.486 |
|
| 2010 |
Advani AS, Gundacker HM, Sala-Torra O, Radich JP, Lai R, Slovak ML, Lancet JE, Coutre SE, Stuart RK, Mims MP, Stiff PJ, Appelbaum FR. Southwest Oncology Group Study S0530: A phase 2 trial of clofarabine and cytarabine for relapsed or refractory acute lymphocytic leukaemia British Journal of Haematology. 151: 430-434. PMID 21113977 DOI: 10.1111/J.1365-2141.2010.08387.X |
0.309 |
|
| 2010 |
Perrone G, Morini S, Santini D, Rabitti C, Vincenzi B, Alloni R, Antinori A, Magistrelli P, Lai R, Cass C, Mackey JR, Coppola R, Tonini G, Muda AO. Human equilibrative nucleoside transporter 1 and carcinoma of the ampulla of Vater: expression differences in tumour histotypes European Journal of Histochemistry. 54: 38. PMID 20839414 DOI: 10.4081/Ejh.2010.E38 |
0.341 |
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| 2010 |
Armanious H, Deschenes J, Gelebart P, Ghosh S, Mackey J, Lai R. Clinical and biological significance of GSK-3β inactivation in breast cancer-an immunohistochemical study. Human Pathology. 41: 1657-63. PMID 20709358 DOI: 10.1016/J.Humpath.2010.04.015 |
0.328 |
|
| 2010 |
Maréchal R, Mackey JR, Lai R, Demetter P, Peeters M, Polus M, Cass CE, Salmon I, Devière J, Van Laethem JL. Deoxycitidine kinase is associated with prolonged survival after adjuvant gemcitabine for resected pancreatic adenocarcinoma. Cancer. 116: 5200-6. PMID 20669326 DOI: 10.1002/Cncr.25303 |
0.359 |
|
| 2010 |
Craik AC, Veldhoen RA, Czernick M, Buckland TW, Kyselytzia K, Ghosh S, Lai R, Damaraju S, Underhill DA, Mackey JR, Goping IS. The BH3-only protein Bad confers breast cancer taxane sensitivity through a nonapoptotic mechanism. Oncogene. 29: 5381-5391. PMID 20603619 DOI: 10.1038/Onc.2010.272 |
0.398 |
|
| 2010 |
Zak Z, Gelebart P, Lai R. Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNFα/NF-κB signaling axis Leukemia. 24: 1476-1486. PMID 20520642 DOI: 10.1038/Leu.2010.117 |
0.348 |
|
| 2010 |
Hegazy SA, Wang P, Anand M, Ingham RJ, Gelebart P, Lai R. The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions Journal of Biological Chemistry. 285: 19813-19820. PMID 20424160 DOI: 10.1074/Jbc.M110.121988 |
0.753 |
|
| 2010 |
Wu F, Wang P, Zhang J, Young LC, Lai R, Li L. Studies of phosphoproteomic changes induced by nucleophosmin-anaplastic lymphoma kinase (ALK) highlight deregulation of tumor necrosis factor (TNF)/Fas/TNF-related apoptosis-induced ligand signaling pathway in ALK-positive anaplastic large cell lymphoma Molecular and Cellular Proteomics. 9: 1616-1632. PMID 20393185 DOI: 10.1074/Mcp.M000153-Mcp201 |
0.372 |
|
| 2010 |
Santini D, Vincenzi B, Fratto ME, Perrone G, Lai R, Catalano V, Cass C, Ruffini PA, Spoto C, Muretto P, Rizzo S, Muda AO, Mackey JR, Russo A, Tonini G, et al. Prognostic role of human equilibrative transporter 1 (hENT1) in patients with resected gastric cancer. Journal of Cellular Physiology. 223: 384-8. PMID 20082300 DOI: 10.1002/Jcp.22045 |
0.355 |
|
| 2010 |
Molavi O, Mahmud A, Hamdy S, Hung RW, Lai R, Samuel J, Lavasanifar A. Development of a poly(D,L-lactic-co-glycolic acid) nanoparticle formulation of STAT3 inhibitor JSI-124: Implication for cancer immunotherapy Molecular Pharmaceutics. 7: 364-374. PMID 20030320 DOI: 10.1021/Mp900145G |
0.311 |
|
| 2010 |
Wang P, Wu F, Ma Y, Li L, Lai R, Young LC. Functional characterization of the kinase activation loop in nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) using tandem affinity purification and liquid chromatography-mass spectrometry Journal of Biological Chemistry. 285: 95-103. PMID 19887368 DOI: 10.1074/Jbc.M109.059758 |
0.377 |
|
| 2010 |
Shi P, Chandra J, Sun X, Gergely M, Cortes JE, Garcia-Manero G, Arlinghaus RB, Lai R, Amin HM. Inhibition of IGF-IR tyrosine kinase induces apoptosis and cell cycle arrest in imatinib-resistant chronic myeloid leukaemia cells. Journal of Cellular and Molecular Medicine. 14: 1777-92. PMID 19508387 DOI: 10.1111/J.1582-4934.2009.00795.X |
0.415 |
|
| 2010 |
Goswami RS, Waldron L, Reis PP, Xuan Y, Xu W, Kuruvilla J, Good D, Bailey D, Church A, Baetz T, LeBrun D, Lai R, Sehn L, Farinha P, Gascoyne RD, et al. Comparing MicroRNA Expression In Aggressive and Indolent Non-Hodgkin Lymphomas Identifies a Prognostic Signature for Mantle Cell Lymphoma Blood. 116: 800-800. DOI: 10.1182/Blood.V116.21.800.800 |
0.332 |
|
| 2010 |
Armanious H, Deschenes J, Gelebart P, Ghosh S, Mackey J, Lai R. Abstract A1: Clinical and biological significance of GSK-3β inactivation in breast cancer: An immunohistochemical study Clinical Cancer Research. 16. DOI: 10.1158/1078-0432.Tcmusa10-A1 |
0.304 |
|
| 2009 |
Alinari L, White VL, Earl CT, Ryan TP, Johnston JS, Dalton JT, Ferketich AK, Lai R, Lucas DM, Porcu P, Blum KA, Byrd JC, Baiocchi RA. Combination bortezomib and rituximab treatment affects multiple survival and death pathways to promote apoptosis in mantle cell lymphoma. Mabs. 1: 31-40. PMID 20046572 DOI: 10.4161/Mabs.1.1.7472 |
0.46 |
|
| 2009 |
Lesniak D, Xu Y, Deschenes J, Lai R, Thoms J, Murray D, Gosh S, Mackey JR, Sabri S, Abdulkarim B. Beta1-integrin circumvents the antiproliferative effects of trastuzumab in human epidermal growth factor receptor-2-positive breast cancer. Cancer Research. 69: 8620-8. PMID 19887601 DOI: 10.1158/0008-5472.Can-09-1591 |
0.377 |
|
| 2009 |
Dien Bard J, Gelebart P, Anand M, Zak Z, Hegazy SA, Amin HM, Lai R. IL-21 contributes to JAK3/STAT3 activation and promotes cell growth in ALK-positive anaplastic large cell lymphoma. The American Journal of Pathology. 175: 825-34. PMID 19608866 DOI: 10.2353/Ajpath.2009.080982 |
0.759 |
|
| 2009 |
Gelebart P, Zak Z, Anand M, Dien-Bard J, Amin HM, Lai R. Interleukin-21 effectively induces apoptosis in mantle cell lymphoma through a STAT1-dependent mechanism Leukemia. 23: 1836-1846. PMID 19494838 DOI: 10.1038/Leu.2009.100 |
0.387 |
|
| 2009 |
Wang P, Lo A, Young JB, Song JH, Lai R, Kneteman NM, Hao C, Li L. Targeted quantitative mass spectrometric identification of differentially expressed proteins between Bax-expressing and deficient colorectal carcinoma cells. Journal of Proteome Research. 8: 3403-14. PMID 19425606 DOI: 10.1021/Pr9000477 |
0.335 |
|
| 2009 |
Shi P, Lai R, Lin Q, Iqbal AS, Young LC, Kwak LW, Ford RJ, Amin HM. IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK+ anaplastic large-cell lymphoma cells. Blood. 114: 360-70. PMID 19423729 DOI: 10.1182/Blood-2007-11-125658 |
0.454 |
|
| 2009 |
Maréchal R, Mackey JR, Lai R, Demetter P, Peeters M, Polus M, Cass CE, Young J, Salmon I, Devière J, Van Laethem JL. Human equilibrative nucleoside transporter 1 and human concentrative nucleoside transporter 3 predict survival after adjuvant gemcitabine therapy in resected pancreatic adenocarcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 2913-9. PMID 19318496 DOI: 10.1158/1078-0432.Ccr-08-2080 |
0.333 |
|
| 2009 |
Carlotti E, Wrench D, Matthews J, Iqbal S, Davies A, Norton A, Hart J, Lai R, Montoto S, Gribben JG, Lister TA, Fitzgibbon J. Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone. Blood. 113: 3553-7. PMID 19202129 DOI: 10.1182/Blood-2008-08-174839 |
0.33 |
|
| 2009 |
Dien Bard J, Gelebart P, Amin HM, Young LC, Ma Y, Lai R. Signal transducer and activator of transcription 3 is a transcriptional factor regulating the gene expression of SALL4 Faseb Journal. 23: 1405-1414. PMID 19151334 DOI: 10.1096/Fj.08-117721 |
0.368 |
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| 2009 |
Sen F, Lai R, Albitar M. Chronic lymphocytic leukemia with t(14;18) and trisomy 12. Archives of Pathology & Laboratory Medicine. 126: 1543-1546. PMID 12456221 DOI: 10.1043/0003-9985(2002)126<1543:Cllwta>2.0.Co;2 |
0.317 |
|
| 2009 |
Toman I, Loree J, Klimowicz A, Bahlis NJ, Lai R, Belch A, Pilarski LM, Reiman T. High Oct-2 Protein Expression Is Associated with Decreased Overall Survival, While High Bob-1 Protein Expression Is Associated with Improved Overall Survival in Myeloma Patients. Blood. 114: 2822-2822. DOI: 10.1182/Blood.V114.22.2822.2822 |
0.351 |
|
| 2008 |
Hsi E, Jung S, Lai R, Johnson J, Cook J, Jones D, DeVos S, Cheson BD, Damon LE, Said J. Ki67 and PIM1 expression in aggressively treated mantle cell lymphoma (MCL): A Cancer and Leukemia Group B (CALGB) 59909 correlative science study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 8560. PMID 27951218 DOI: 10.1200/Jco.2008.26.15_Suppl.8560 |
0.4 |
|
| 2008 |
Hsi ED, Jung SH, Lai R, Johnson JL, Cook JR, Jones D, Devos S, Cheson B, Damon LE, Said J. Ki67 and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: A Cancer and Leukemia Group B 59909 correlative science study Leukemia and Lymphoma. 49: 2081-2090. PMID 19021050 DOI: 10.1080/10428190802419640 |
0.437 |
|
| 2008 |
Gelebart P, Anand M, Armanious H, Peters AC, Dien Bard J, Amin HM, Lai R. Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma. Blood. 112: 5171-9. PMID 18787224 DOI: 10.1182/Blood-2008-02-139212 |
0.481 |
|
| 2008 |
Bard JD, Gelebart P, Anand M, Amin H, Lai R. Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma. Leukemia. 22: 1595-1603. PMID 18509351 DOI: 10.1038/Leu.2008.129 |
0.31 |
|
| 2008 |
Lai R, Bartlett NL, Mackey JR, Jung SH, Johnson JL, Cook JR, Jones D, Cass CE, Young JD, Said J, Cheson B, Hsi ED. High expression of nucleoside transporter protein hENT1 in Reed-Sternberg cells is associated with treatment failure in relapsed/ refractory Hodgkin lymphoma patients treated with gemcitabine, vinorelbine and liposomal doxorubicin - A CALGB 59804 correlative study Leukemia and Lymphoma. 49: 1202-1205. PMID 18452103 DOI: 10.1080/10428190802094237 |
0.386 |
|
| 2008 |
Rizzatti EG, Mora-Jensen H, Weniger MA, Gibellini F, Lee E, Daibata M, Lai R, Wiestner A. Noxa mediates bortezomib induced apoptosis in both sensitive and intrinsically resistant mantle cell lymphoma cells and this effect is independent of constitutive activity of the AKT and NF-kappaB pathways. Leukemia & Lymphoma. 49: 798-808. PMID 18398749 DOI: 10.1080/10428190801910912 |
0.391 |
|
| 2008 |
Evans RP, Naber C, Steffler T, Checkland T, Maxwell CA, Keats JJ, Belch AR, Pilarski LM, Lai R, Reiman T. The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma. British Journal of Haematology. 140: 295-302. PMID 18076711 DOI: 10.1111/j.1365-2141.2007.06913.x |
0.334 |
|
| 2008 |
Hsi ED, Said J, Johnson JL, Jung S, Lai R, Jones D, Chadburn A, Cheson BD, Wilson WH. Biologic Prognostic Markers in Diffuse Large B-Cell Lymphoma Patients Treated with Dose Adjusted EPOCH-R: a CALGB 50103 Correlative Science Study Blood. 112: 476-476. DOI: 10.1182/Blood.V112.11.476.476 |
0.351 |
|
| 2008 |
Peters AC, Chung R, Wong CS, Young LC, Reiman T, Lai R. Epigenetic Regulation of the WNT Canonical Pathway in Mantle Cell Lymphoma. Blood. 112: 3340-3340. DOI: 10.1182/Blood.V112.11.3340.3340 |
0.42 |
|
| 2007 |
Santini D, Perrone G, Vincenzi B, Lai R, Cass C, Alloni R, Rabitti C, Antinori A, Vecchio F, Morini S, Magistrelli P, Coppola R, Mackey JR, Tonini G. Human equilibrative nucleoside transporter 1 (hENT1) protein is associated with short survival in resected ampullary cancer Annals of Oncology. 19: 724-728. PMID 18187485 DOI: 10.1093/Annonc/Mdm576 |
0.366 |
|
| 2007 |
Young LC, Keuling AM, Lai R, Nation PN, Tron VA, Andrew SE. The associated contributions of p53 and the DNA mismatch repair protein Msh6 to spontaneous tumorigenesis. Carcinogenesis. 28: 2131-8. PMID 17615258 DOI: 10.1093/Carcin/Bgm153 |
0.332 |
|
| 2007 |
Amin HM, Lai R. Pathobiology of ALK+ anaplastic large-cell lymphoma Blood. 110: 2259-2267. PMID 17519389 DOI: 10.1182/blood-2007-04-060715 |
0.361 |
|
| 2007 |
Amin H, Hoshino K, Yang H, Lin Q, Lai R, Garcia-Manero G. Decreased expression level of SH2 domain-containing protein tyrosine phosphatase-1 (Shp1) is associated with progression of chronic myeloid leukaemia. The Journal of Pathology. 212: 402-410. PMID 17503411 DOI: 10.1002/Path.2178 |
0.398 |
|
| 2007 |
Lwin T, Hazlehurst LA, Dessureault S, Lai R, Bai W, Sotomayor E, Moscinski LC, Dalton WS, Tao J. Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas. Blood. 110: 1631-8. PMID 17502456 DOI: 10.1182/Blood-2006-11-060350 |
0.468 |
|
| 2007 |
Chung R, Lai R, Wei P, Lee J, Hanson J, Belch AR, Turner AR, Reiman T. Concordant but not discordant bone marrow involvement in diffuse large B-cell lymphoma predicts a poor clinical outcome independent of the International Prognostic Index. Blood. 110: 1278-82. PMID 17475910 DOI: 10.1182/Blood-2007-01-070300 |
0.353 |
|
| 2007 |
Horne G, Medlicott SA, Mansoor A, Lategan J, Lai R, Beck P. A definitive diagnosis of primary Hodgkin lymphoma on endoscopic biopsy material utilizing in-depth immunohistochemical analysis. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 21: 185-8. PMID 17377648 DOI: 10.1155/2007/362360 |
0.32 |
|
| 2007 |
Mansoor A, Akbari M, Auer I, Lai R. Cyclin D1 and t(11;14)-positive B-cell neoplasms resembling marginal zone B-cell lymphoma: a morphological variant of mantle cell lymphoma. Human Pathology. 38: 797-802. PMID 17316759 DOI: 10.1016/J.Humpath.2006.10.017 |
0.418 |
|
| 2007 |
Slack GW, Wizniak J, Dabbagh L, Shi X, Gelebart P, Lai R. Flow cytometric detection of ZAP-70 in chronic lymphocytic leukemia: correlation with immunocytochemistry and Western blot analysis. Archives of Pathology & Laboratory Medicine. 131: 50-56. PMID 17227123 DOI: 10.1043/1543-2165(2007)131[50:Fcdozi]2.0.Co;2 |
0.378 |
|
| 2007 |
Kaptan MA, Hui D, Dabbagh L, Reiman T, Lai R. Enteropathy type T cell lymphoma with an unusually late relapse: a case report. Journal of Clinical Pathology. 60: 108-108. PMID 17213361 DOI: 10.1136/Jcp.2005.036517 |
0.35 |
|
| 2007 |
Carlotti E, Wrench D, Iqbal S, O’Shea D, Davies A, Virappane P, Hart J, Lai R, Gribben JG, Lister AT, Fitzgibbon J. Determining the Mechanism of Transformation of Follicular Lymphoma into Diffuse Large B Cell Lymphoma. Blood. 110: 181-181. DOI: 10.1182/Blood.V110.11.181.181 |
0.364 |
|
| 2006 |
Johnson L, Lai R, Santos C, Dabbagh L, Mackey J. Unexpected immunohistochemical localization of deoxycytidine kinase. Clinical Cancer Research. 12: 6863-6863. PMID 17121908 DOI: 10.1158/1078-0432.Ccr-06-1590 |
0.3 |
|
| 2006 |
Rosen DG, Mercado-Uribe I, Yang G, Bast RC, Amin HM, Lai R, Liu J. The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis. Cancer. 107: 2730-40. PMID 17063503 DOI: 10.1002/Cncr.22293 |
0.402 |
|
| 2006 |
Cui W, Kong NR, Ma Y, Amin HM, Lai R, Chai L. Differential expression of the novel oncogene, SALL4, in lymphoma, plasma cell myeloma, and acute lymphoblastic leukemia. Modern Pathology. 19: 1585-1592. PMID 16998462 DOI: 10.1038/Modpathol.3800694 |
0.445 |
|
| 2006 |
Lai R, Lefresne SV, Franko B, Hui D, Mirza I, Mansoor A, Amin HM, Ma Y. Immunoglobulin VH somatic hypermutation in mantle cell lymphoma: mutated genotype correlates with better clinical outcome. Modern Pathology. 19: 1498-1505. PMID 16980950 DOI: 10.1038/Modpathol.3800677 |
0.321 |
|
| 2006 |
Shi X, Franko B, Frantz C, Amin HM, Lai R. JSI-124 (cucurbitacin I) inhibits Janus kinase-3/signal transducer and activator of transcription-3 signalling, downregulates nucleophosmin-anaplastic lymphoma kinase (ALK), and induces apoptosis in ALK-positive anaplastic large cell lymphoma cells. British Journal of Haematology. 135: 26-32. PMID 16939498 DOI: 10.1111/J.1365-2141.2006.06259.X |
0.475 |
|
| 2006 |
Hui D, Dabbagh L, Hanson J, Amin H, Lai R. High ZAP-70 expression correlates with worse clinical outcome in mantle cell lymphoma. Leukemia. 20: 1905-1908. PMID 16932342 DOI: 10.1038/Sj.Leu.2404362 |
0.369 |
|
| 2006 |
Dien J, Amin HM, Chiu N, Wong W, Frantz C, Chiu B, Mackey JR, Lai R. Signal transducers and activators of transcription-3 up-regulates tissue inhibitor of metalloproteinase-1 expression and decreases invasiveness of breast cancer. The American Journal of Pathology. 169: 633-42. PMID 16877361 DOI: 10.2353/Ajpath.2006.051109 |
0.379 |
|
| 2006 |
Han Y, Amin HM, Frantz C, Franko B, Lee J, Lin Q, Lai R. Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma Leukemia. 20: 1602-1609. PMID 16871283 DOI: 10.1038/Sj.Leu.2404323 |
0.441 |
|
| 2006 |
Han Y, Amin HM, Franko B, Frantz C, Shi X, Lai R. Loss of SHP1 enhances JAK3/STAT3 signaling and decreases proteosome degradation of JAK3 and NPM-ALK in ALK+ anaplastic large-cell lymphoma. Blood. 108: 2796-803. PMID 16825495 DOI: 10.1182/blood-2006-04-017434 |
0.407 |
|
| 2006 |
Hui D, Satkunam N, Kaptan MA, Reiman T, Lai R. Pathway-specific apoptotic gene expression profiling in chronic lymphocytic leukemia and follicular lymphoma Modern Pathology. 19: 1192-1202. PMID 16763612 DOI: 10.1038/Modpathol.3800632 |
0.351 |
|
| 2006 |
Qiu L, Lai R, Lin Q, Lau E, Thomazy DM, Calame D, Ford RJ, Kwak LW, Kirken RA, Amin HM. Autocrine release of interleukin-9 promotes Jak3-dependent survival of ALK+ anaplastic large-cell lymphoma cells. Blood. 108: 2407-15. PMID 16763206 DOI: 10.1182/Blood-2006-04-020305 |
0.417 |
|
| 2006 |
Marzec M, Kasprzycka M, Lai R, Gladden AB, Wlodarski P, Tomczak E, Nowell P, Deprimo SE, Sadis S, Eck S, Schuster SJ, Diehl JA, Wasik MA. Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity. Blood. 108: 1744-50. PMID 16690963 DOI: 10.1182/Blood-2006-04-016634 |
0.456 |
|
| 2006 |
Chai L, Yang J, Di C, Cui W, Kawakami K, Lai R, Ma Y. Transcriptional Activation of the SALL1 by the Human SIX1 Homeodomain during Kidney Development Journal of Biological Chemistry. 281: 18918-18926. PMID 16670092 DOI: 10.1074/Jbc.M600180200 |
0.328 |
|
| 2006 |
Amin HM, Lin Q, Lai R. Jak3 contributes to the activation of ALK and Stat3 in ALK(+) anaplastic large cell lymphoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 417-9; author reply . PMID 16554750 DOI: 10.1038/Labinvest.3700393 |
0.452 |
|
| 2006 |
Lai R, Navid F, Rodriguez-Galindo C, Liu T, Fuller CE, Ganti R, Dien J, Dalton J, Billups C, Khoury JD. STAT3 is activated in a subset of the Ewing sarcoma family of tumours. The Journal of Pathology. 208: 624-32. PMID 16463269 DOI: 10.1002/Path.1941 |
0.371 |
|
| 2006 |
Lai R, Hsi ED, Mackey J, Jung S, Johnson JL, Cook JR, Jones D, Said JW, Cheson BD, Bartlett NL. High expression of nucleoside transporter hENT1 predicts a worse event-free survival in relapsed/refractory Hodgkin lymphoma patients treated with gemcitabine, vinorelbine, and liposomal doxorubicin—A CALGB 59804 correlative study Journal of Clinical Oncology. 24: 7581-7581. DOI: 10.1200/Jco.2006.24.18_Suppl.7581 |
0.369 |
|
| 2006 |
Reiman T, Lai R, Ding K, Winton T, Butts C, Mackey J, Dabbagh L, Seymour L, Tsao M, Shepherd F, Seve P. Class III beta tubulin expression and benefit from adjuvant cisplatin/vinorelbine chemotherapy in operable non-small cell lung cancer: Analysis of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) study JBR.10 Journal of Clinical Oncology. 24: 7051-7051. DOI: 10.1200/Jco.2006.24.18_Suppl.7051 |
0.342 |
|
| 2006 |
Rizzatti EG, Mora-Jensen H, Lai R, Daibata M, White T, Dunleavy K, Wilson W, Wiestner A. Bortezomib Induces an Antioxidant and ER-Stress Response Gene Expression Signature in Mantle Cell Lymphoma: Implications for Response Prediction and Optimized Chemotherapy Regimens. Blood. 108: 830-830. DOI: 10.1182/Blood.V108.11.830.830 |
0.421 |
|
| 2006 |
Rizzatti EG, Mora-Jensen H, Lee E, Miura Y, Lai R, Daibata M, Wiestner A. Bortezomib Activity Against Mantle Cell Lymphoma Overcomes Classic Mechanisms of Drug Resistance and Targets Cell Cycle Control. Blood. 108: 4393-4393. DOI: 10.1182/Blood.V108.11.4393.4393 |
0.399 |
|
| 2006 |
Hart J, Turner AR, Larratt LM, Russell JA, Franko B, Frantz C, Paonessa T, Mansoor A, Lai R. Transmission of a Follicular Lymphoma by Allogeneic Bone Marrow Tranplantation — Evidence to Support the Existence of a Lymphoma Progenitor Cell. Blood. 108: 2415-2415. DOI: 10.1182/Blood.V108.11.2415.2415 |
0.408 |
|
| 2005 |
Lin Q, Lai R, Chirieac LR, Li C, Thomazy VA, Grammatikakis I, Rassidakis GZ, Zhang W, Fujio Y, Kunisada K, Hamilton SR, Amin HM. Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells. The American Journal of Pathology. 167: 969-80. PMID 16192633 DOI: 10.1016/S0002-9440(10)61187-X |
0.35 |
|
| 2005 |
Lai R, Leventaki V, Rassidakis GZ. Re: Rust et al. TIMP-1 expression in anaplastic large cell lymphoma is usually restricted to macrophages and only seldom observed in tumour cells. J Pathol 2005;206:445-450. The Journal of Pathology. 207: 372-373. PMID 16161018 DOI: 10.1002/Path.1842 |
0.358 |
|
| 2005 |
Lai R, Rassidakis GZ, Lin Q, Atwell C, Medeiros LJ, Amin HM. Jak3 activation is significantly associated with ALK expression in anaplastic large cell lymphoma. Human Pathology. 36: 939-44. PMID 16153455 DOI: 10.1016/j.humpath.2005.07.011 |
0.331 |
|
| 2005 |
Yared MA, Khoury JD, Medeiros LJ, Rassidakis GZ, Lai R. Activation status of the JAK/STAT3 pathway in mantle cell lymphoma. Archives of Pathology & Laboratory Medicine. 129: 990-6. PMID 16048411 DOI: 10.5858/2005-129-990-ASOTSP |
0.353 |
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| 2005 |
Hui D, Reiman T, Hanson J, Linford R, Wong W, Belch A, Lai R. Immunohistochemical detection of cdc2 is useful in predicting survival in patients with mantle cell lymphoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 18: 1223-31. PMID 15933757 DOI: 10.1038/Modpathol.3800409 |
0.36 |
|
| 2005 |
Drakos E, Rassidakis GZ, Tsioli P, Lai R, Jones D, Medeiros LJ. Differential expression of WT1 gene product in non-Hodgkin lymphomas. Applied Immunohistochemistry & Molecular Morphology : Aimm. 13: 132-7. PMID 15894924 DOI: 10.1097/01.pai.0000143786.62974.66 |
0.36 |
|
| 2005 |
Mackey JR, Galmarini CM, Graham KA, Joy AA, Delmer A, Dabbagh L, Glubrecht D, Jewell LD, Lai R, Lang T, Hanson J, Young JD, Merle-Béral H, Binet JL, Cass CE, et al. Quantitative analysis of nucleoside transporter and metabolism gene expression in chronic lymphocytic leukemia (CLL): identification of fludarabine-sensitive and -insensitive populations. Blood. 105: 767-74. PMID 15454483 DOI: 10.1182/Blood-2004-03-1046 |
0.33 |
|
| 2005 |
Rassidakis GZ, Feretzaki M, Atwell C, Grammatikakis I, Lin Q, Lai R, Claret FX, Medeiros LJ, Amin HM. Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma. Blood. 105: 827-9. PMID 15374880 DOI: 10.1182/Blood-2004-06-2125 |
0.438 |
|
| 2005 |
Lin Q, Prudkin ML, Kantarjian HM, Cortes JE, Lau E, Grammatikakis I, Thomazy VA, Lai R, Amin HM. Role of Jak3 in Chronic Myeloid Leukemia: Evidence To Identify Jak3 as a Potential Therapeutic Target. Blood. 106: 2870-2870. DOI: 10.1182/Blood.V106.11.2870.2870 |
0.443 |
|
| 2005 |
Rizzatti EG, Mora-Jensen HI, Billings E, Lai R, Wiestner A. Gene Expression Analysis Uncovers Possible Resistance Mechanisms to Bortezomib in Mantle Cell Lymphoma That Differ from Mechanisms Identified in Other Lymphoid Malignancies. Blood. 106: 2412-2412. DOI: 10.1182/Blood.V106.11.2412.2412 |
0.402 |
|
| 2005 |
Wadehra N, Lin T, Ryan T, Schneider A, Pepple A, Johnston J, Dalton J, Banks A, Eisenbeis CF, Lai R, Byrd JC, Blum K, Baiocchi RA. Combination Bortezomib (PS341, Velcade) and Rituximab Treatment Affects Multiple Survival and Death Pathways To Promote Apoptosis in Mantle Cell Lymphoma. Blood. 106: 2407-2407. DOI: 10.1182/Blood.V106.11.2407.2407 |
0.411 |
|
| 2004 |
Khoury JD, Rassidakis GZ, Medeiros LJ, Amin HM, Lai R. Methylation of SHP1 gene and loss of SHP1 protein expression are frequent in systemic anaplastic large cell lymphoma. Blood. 104: 1580-1581. PMID 15317731 DOI: 10.1182/Blood-2004-03-1151 |
0.473 |
|
| 2004 |
Amin HM, McDonnell TJ, Ma Y, Lin Q, Fujio Y, Kunisada K, Leventaki V, Das P, Rassidakis GZ, Cutler C, Medeiros LJ, Lai R. Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma. Oncogene. 23: 5426-34. PMID 15184887 DOI: 10.1038/Sj.Onc.1207703 |
0.423 |
|
| 2004 |
Rassidakis GZ, Lai R, Herling M, Cromwell C, Schmitt-Graeff A, Medeiros LJ. Retinoblastoma protein is frequently absent or phosphorylated in anaplastic large-cell lymphoma. The American Journal of Pathology. 164: 2259-67. PMID 15161658 DOI: 10.1016/S0002-9440(10)63782-0 |
0.326 |
|
| 2004 |
Lai R, Rassidakis GZ, Medeiros LJ, Ramdas L, Goy AH, Cutler C, Fujio Y, Kunisada K, Amin HM, Gilles F. Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. The American Journal of Pathology. 164: 2251-8. PMID 15161657 DOI: 10.1016/S0002-9440(10)63781-9 |
0.385 |
|
| 2004 |
Schlette EJ, Medeiros LJ, Goy A, Lai R, Rassidakis GZ. Survivin expression predicts poorer prognosis in anaplastic large-cell lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 1682-8. PMID 15117990 DOI: 10.1200/JCO.2004.10.172 |
0.306 |
|
| 2004 |
Drakos E, Rassidakis GZ, Lai R, Herling M, O'Connor SL, Schmitt-Graeff A, McDonnell TJ, Medeiros LJ. Caspase-3 activation in systemic anaplastic large-cell lymphoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 17: 109-16. PMID 14657946 DOI: 10.1038/Modpathol.3800039 |
0.34 |
|
| 2004 |
Khoury JD, Medeiros LJ, Rassidakis GZ, Yared MA, Tsioli P, Leventaki V, Schmitt-Graeff A, Herling M, Amin HM, Lai R. Differential expression and clinical significance of tyrosine-phosphorylated STAT3 in ALK+ and ALK- anaplastic large cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 3692-9. PMID 14506160 |
0.391 |
|
| 2004 |
Wiestner A, Chiorazzi M, Lai R, Rosenwald A, Muller-Hermelink HK, Ott G, Chan WC, Greiner TC, Weisenburger DD, Vose J, Armitage JO, Gascoyne RD, Connors JM, Campo E, Montserrat E, et al. High Cyclin D1 Expression Is Associated with Increased Proliferation Rate and Decreased Survival in Mantle Cell Lymphoma (MCL) and Is Caused by Genomic Deletions and Mutations that Enhance Stability of Cyclin D1 mRNA. Blood. 104: 697-697. DOI: 10.1182/Blood.V104.11.697.697 |
0.36 |
|
| 2003 |
Amin HM, Medeiros LJ, Ma Y, Feretzaki M, Das P, Leventaki V, Rassidakis GZ, O'Connor SL, McDonnell TJ, Lai R. Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma. Oncogene. 22: 5399-407. PMID 12934099 DOI: 10.1038/Sj.Onc.1206849 |
0.36 |
|
| 2003 |
Amin HM, McDonnell TJ, Medeiros LJ, Rassidakis GZ, Leventaki V, O'Connor SL, Keating MJ, Lai R. Characterization of 4 mantle cell lymphoma cell lines. Archives of Pathology & Laboratory Medicine. 127: 424-31. PMID 12683869 DOI: 10.1043/0003-9985(2003)127<0424:Comclc>2.0.Co;2 |
0.317 |
|
| 2003 |
Rassidakis GZ, Claret FX, Lai R, Zhang Q, Sarris AH, McDonnell TJ, Medeiros LJ. Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1121-8. PMID 12631617 |
0.321 |
|
| 2003 |
Chan JA, Olvera M, Lai R, Naing W, Rezk SA, Brynes RK. Immunohistochemical expression of the transcription factor DP-1 and its heterodimeric partner E2F-1 in non-Hodgkin lymphoma. Applied Immunohistochemistry & Molecular Morphology : Aimm. 10: 322-6. PMID 12607600 DOI: 10.1097/00129039-200212000-00006 |
0.373 |
|
| 2003 |
Khoury JD, Medeiros LJ, Rassidakis GZ, McDonnell TJ, Abruzzo LV, Lai R. Expression of Mcl-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression. The Journal of Pathology. 199: 90-7. PMID 12474231 DOI: 10.1002/Path.1254 |
0.37 |
|
| 2003 |
Lai R, Rassidakis GZ, Medeiros LJ, Leventaki V, Keating M, McDonnell TJ. Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours. The Journal of Pathology. 199: 84-9. PMID 12474230 DOI: 10.1002/Path.1253 |
0.36 |
|
| 2002 |
Rassidakis GZ, Lai R, McDonnell TJ, Cabanillas F, Sarris AH, Medeiros LJ. Overexpression of Mcl-1 in anaplastic large cell lymphoma cell lines and tumors. The American Journal of Pathology. 160: 2309-10. PMID 12057933 DOI: 10.1016/S0002-9440(10)61178-9 |
0.331 |
|
| 2001 |
Nagasaka T, Lai R, Kuno K, Nakashima T, Nakashima N. Localized amyloidosis and extramedullary plasmacytoma involving the larynx of a child. Human Pathology. 32: 132-134. PMID 11172308 DOI: 10.1053/Hupa.2001.20896 |
0.302 |
|
| 2000 |
Lai R, Juco J, Lee SF, Nahirniak S, Etches WS. Flow cytometric detection of CD79a expression in T-cell acute lymphoblastic leukemias. American Journal of Clinical Pathology. 113: 823-830. PMID 10874883 DOI: 10.1309/391R-93Yf-Db4D-1L35 |
0.365 |
|
| 2000 |
Lai R, Medeiros LJ, Dabbagh L, Formenti KS, Coupland RW. Sinusoidal CD30-positive large B-cell lymphoma: a morphologic mimic of anaplastic large cell lymphoma. Modern Pathology. 13: 223-228. PMID 10757332 DOI: 10.1038/Modpathol.3880041 |
0.423 |
|
| 2000 |
Lai R, Larratt LM, Etches W, Mortimer ST, Jewell LD, Dabbagh L, Coupland RW. Hepatosplenic T-cell lymphoma of αβ lineage in a 16-year-old boy presenting with hemolytic anemia and thrombocytopenia The American Journal of Surgical Pathology. 24: 459-463. PMID 10716161 DOI: 10.1097/00000478-200003000-00016 |
0.334 |
|
| 1998 |
Lai R, Redburn J, Nguyen G. Cytodiagnosis of metastatic amelanotic melanomas by fine‐needle aspiration biopsy Cancer. 84: 92-97. PMID 9570211 DOI: 10.1002/(Sici)1097-0142(19980425)84:2<92::Aid-Cncr4>3.0.Co;2-F |
0.355 |
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