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Wenying Yu, Ph.D. - Publications

Affiliations: 
2013 Pharmacy Ohio State University, Columbus, Columbus, OH 
Area:
Pharmacology
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Liu Z, Ma L, Sun Y, Yu W, Wang X. Targeting STAT3 signaling overcomes gefitinib resistance in non-small cell lung cancer. Cell Death & Disease. 12: 561. PMID 34059647 DOI: 10.1038/s41419-021-03844-z  0.321
2021 Ren Y, Li S, Zhu R, Wan C, Song D, Zhu J, Cai G, Long S, Kong L, Yu W. Discovery of STAT3 and Histone Deacetylase (HDAC) Dual-Pathway Inhibitors for the Treatment of Solid Cancer. Journal of Medicinal Chemistry. PMID 34043359 DOI: 10.1021/acs.jmedchem.1c00136  0.406
2021 Chen RL, Wang Z, Huang P, Sun CH, Yu WY, Zhang HH, Yu CH, He JQ. Isovitexin potentiated the antitumor activity of cisplatin by inhibiting the glucose metabolism of lung cancer cells and reduced cisplatin-induced immunotoxicity in mice. International Immunopharmacology. 107357. PMID 33715980 DOI: 10.1016/j.intimp.2020.107357  0.324
2020 Song D, Yu W, Ren Y, Zhu J, Wan C, Cai G, Guo J, Zhang W, Kong L. Discovery of bazedoxifene analogues targeting glycoprotein 130. European Journal of Medicinal Chemistry. 199: 112375. PMID 32388278 DOI: 10.1016/J.Ejmech.2020.112375  0.431
2020 Xu G, Zhang Y, Wang H, Guo Z, Wang X, Li X, Chang S, Sun T, Yu Z, Xu T, Zhao L, Wang Y, Yu W. Synthesis and biological evaluation of 4-(pyridin-4-oxy)-3-(3,3-difluorocyclobutyl)-pyrazole derivatives as novel potent transforming growth factor-β type 1 receptor inhibitors. European Journal of Medicinal Chemistry. 198: 112354. PMID 32387837 DOI: 10.1016/J.Ejmech.2020.112354  0.318
2020 Pan L, Chen X, Fu S, Yu W, Li C, Wang T, Lo HW, Lin J. LLY17, a novel small molecule STAT3 inhibitor induces apoptosis and suppresses cell migration and tumor growth in triple-negative breast cancer. Breast Cancer Research and Treatment. PMID 32240456 DOI: 10.1007/S10549-020-05613-6  0.556
2020 Wang H, Liu Z, Guan L, Li J, Chen S, Yu W, Lai M. LYW-6, a Novel Cryptotanshinone Derived STAT3 Targeting Inhibitor, Suppresses Colorectal Cancer Growth and Metastasis. Pharmacological Research. 104661. PMID 31982491 DOI: 10.1016/j.phrs.2020.104661  0.438
2019 Zhu J, Chen J, Song D, Zhang W, Guo J, Cai G, Ren Y, Wan C, Kong L, Yu W. Real-time monitoring of etoposide prodrug activated by hydrogen peroxide with improved safety. Journal of Materials Chemistry. B. PMID 31720667 DOI: 10.1039/C9Tb02041A  0.35
2019 Liu Z, Wang H, Guan L, Lai C, Yu W, Lai M. LL1, a novel specific STAT3 inhibitor, displays anti-colorectal cancer activities in vitro and in vivo. British Journal of Pharmacology. PMID 31499589 DOI: 10.1111/bph.14863  0.412
2019 Li Y, Wang Y, Shi Z, Liu J, Zheng S, Yang J, Liu Y, Yang Y, Chang F, Yu W. Clinicopathological and Prognostic Role of STAT3/p-STAT3 in Breast Cancer Patients in China: A Meta-Analysis. Scientific Reports. 9: 11243. PMID 31375715 DOI: 10.1038/S41598-019-47556-Z  0.341
2019 Cai G, Yu W, Song D, Zhang W, Guo J, Zhu J, Ren Y, Kong L. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors. European Journal of Medicinal Chemistry. 174: 236-251. PMID 31048139 DOI: 10.1016/J.Ejmech.2019.04.024  0.461
2018 Zhang W, Yu W, Cai G, Zhu J, Zhang C, Li S, Guo J, Yin G, Chen C, Kong L. A new synthetic derivative of cryptotanshinone KYZ3 as STAT3 inhibitor for triple-negative breast cancer therapy. Cell Death & Disease. 9: 1098. PMID 30368518 DOI: 10.1038/S41419-018-1139-Z  0.519
2018 Guo J, Yu W, Cai G, Zhang W, Li S, Zhu J, Song D, Kong L. Discovery of new benzensulfonamide derivatives as tripedal STAT3 inhibitors. European Journal of Medicinal Chemistry. 151: 752-764. PMID 29674294 DOI: 10.1016/J.Ejmech.2018.03.053  0.55
2017 Zhang W, Liu F, Zhang C, Luo JG, Luo J, Yu W, Kong L. Near-infrared Fluorescent Probe with Remarkable Large Stokes Shift and Favorable Water Solubility for Real-time Tracking Leucine Aminopeptidase In Living Cells and In Vivo. Analytical Chemistry. PMID 29048879 DOI: 10.1021/Acs.Analchem.7B03332  0.362
2017 Zhang W, Guo J, Li S, Ma T, Xu D, Han C, Liu F, Yu W, Kong L. Discovery of monocarbonyl curcumin-BTP hybrids as STAT3 inhibitors for drug-sensitive and drug-resistant breast cancer therapy. Scientific Reports. 7: 46352. PMID 28397855 DOI: 10.1038/Srep46352  0.518
2017 Yu W, Li C, Zhang W, Xia Y, Li S, Lin J, Yu K, Liu M, Yang L, Luo JG, Chen Y, Sun H, Kong LY. Discovery of an Orally Selective Inhibitor of Signal Transducer and Activator of Transcription 3 Using Advanced Multiple Ligand Simultaneous Docking. Journal of Medicinal Chemistry. PMID 28245116 DOI: 10.1021/Acs.Jmedchem.6B01489  0.584
2016 Li S, Zhang W, Yang Y, Ma T, Guo J, Wang S, Yu W, Kong L. Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein. European Journal of Medicinal Chemistry. 124: 1006-1018. PMID 27783972 DOI: 10.1016/J.Ejmech.2016.10.028  0.536
2016 Zhang W, Ma T, Li S, Yang Y, Guo J, Yu W, Kong L. Antagonizing STAT3 activation with benzo[b]thiophene 1, 1-dioxide based small molecules. European Journal of Medicinal Chemistry. 125: 538-550. PMID 27718470 DOI: 10.1016/J.Ejmech.2016.09.068  0.546
2015 Che XH, Chen CL, Ye XL, Weng GB, Guo XZ, Yu WY, Tao J, Chen YC, Chen X. Dual inhibition of COX-2/5-LOX blocks colon cancer proliferation, migration and invasion in vitro. Oncology Reports. PMID 26707712 DOI: 10.3892/or.2015.4506  0.329
2015 Xie SS, Wang X, Jiang N, Yu W, Wang KD, Lan JS, Li ZR, Kong LY. Multi-target tacrine-coumarin hybrids: Cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease. European Journal of Medicinal Chemistry. 95: 153-65. PMID 25812965 DOI: 10.1016/J.Ejmech.2015.03.040  0.372
2015 Xiao H, Bid HK, Jou D, Wu X, Yu W, Li C, Houghton PJ, Lin J. A novel small molecular STAT3 inhibitor, LY5, inhibits cell viability, cell migration, and angiogenesis in medulloblastoma cells. The Journal of Biological Chemistry. 290: 3418-29. PMID 25313399 DOI: 10.1074/Jbc.M114.616748  0.615
2014 Xu ZC, Wang XB, Yu WY, Xie SS, Li SY, Kong LY. Design, synthesis and biological evaluation of benzylisoquinoline derivatives as multifunctional agents against Alzheimer's disease. Bioorganic & Medicinal Chemistry Letters. 24: 2368-73. PMID 24726809 DOI: 10.1016/J.Bmcl.2014.03.058  0.321
2014 Yu W, Li C. Regioselective one-pot C-N coupling of substituted naphthoquinones: Selective intramolecular ring fusion of sulfonamides Tetrahedron. 70: 459-464. DOI: 10.1016/J.Tet.2013.11.041  0.402
2013 Yu W, Xiao H, Lin J, Li C. Discovery of novel STAT3 small molecule inhibitors via in silico site-directed fragment-based drug design. Journal of Medicinal Chemistry. 56: 4402-12. PMID 23651330 DOI: 10.1021/Jm400080C  0.577
2013 Yu W, Li C. 4-Nitro-phenyl N-(2-sulfamoylphen-yl)carbamate. Acta Crystallographica. Section E, Structure Reports Online. 69: o355. PMID 23476546 DOI: 10.1107/S1600536813003310  0.328
2013 Xiao H, Yu W, Olson VR, Li C, Houghton P, Lin J. Abstract 3252: A novel small molecule, LY5, selectively inhibits STAT3 phosphorylation and activities and exhibits potent growth suppressive activity in cancer cells. Cancer Research. 73: 3252-3252. DOI: 10.1158/1538-7445.Am2013-3252  0.629
2011 Liu A, Liu Y, Xu Z, Yu W, Wang H, Li C, Lin J. Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells. Cancer Science. 102: 1381-7. PMID 21435102 DOI: 10.1111/J.1349-7006.2011.01932.X  0.614
2011 Liu Y, Liu A, Xu Z, Yu W, Wang H, Li C, Lin J. XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells. Apoptosis : An International Journal On Programmed Cell Death. 16: 502-10. PMID 21311975 DOI: 10.1007/S10495-011-0578-0  0.552
2011 Liu A, Liu Y, Xu Z, Yu W, Wang H, Li C, Lin J. Abstract 5345: A novel small molecule, XZH-5 inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells Cancer Research. 71: 5345-5345. DOI: 10.1158/1538-7445.Am2011-5345  0.629
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