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Spandan Chennamadhavuni - Publications

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Organic synthesis, Medicinal chemistry, Computational chemistry
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hatcher JM, Du G, Fontán L, Us I, Qiao Q, Chennamadhavuni S, Shao J, Wu H, Melnick A, Gray NS, Scott DA. Peptide-based covalent inhibitors of MALT1 paracaspase. Bioorganic & Medicinal Chemistry Letters. PMID 30954428 DOI: 10.1016/J.Bmcl.2019.03.046  0.632
2019 Trilles R, Beglov D, Chen Q, He H, Wireman R, Reed A, Chennamadhavuni S, Panek JS, Brown LE, Vajda S, Porco JA, Kelley MR, Georgiadis MM. Discovery of macrocyclic inhibitors of Apurinic/apyrimidinic endonuclease 1. Journal of Medicinal Chemistry. PMID 30653918 DOI: 10.1021/Acs.Jmedchem.8B01529  0.625
2018 Shoji M, Qian WP, Nagaraju GP, Brat DJ, Pessolano D, Luzietti R, Chennamadhavuni S, Yamaguchi M, Yang L, Liotta DC. Inhibition of breast cancer metastasis to the lungs with UBS109. Oncotarget. 9: 36102-36109. PMID 30546830 DOI: 10.18632/Oncotarget.26302  0.441
2018 Chennamadhavuni S, Panek JS, Porco JA, Brown LE. Diastereodivergent synthesis of chiral tetrahydropyrrolodiazepinediones via a one-pot intramolecular aza-Michael/lactamization sequence. The Journal of Organic Chemistry. PMID 30458107 DOI: 10.1021/Acs.Joc.8B02724  0.505
2018 Fontán L, Qiao Q, Hatcher JM, Casalena G, Us I, Teater M, Durant M, Du G, Xia M, Bilchuk N, Chennamadhavuni S, Palladino G, Inghirami G, Philippar U, Wu H, et al. Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth. The Journal of Clinical Investigation. PMID 30024860 DOI: 10.1172/Jci99436  0.645
2017 Fontan L, Scott D, Hatcher J, Qiao Q, Us I, Casalena G, Bekkers M, Philippar U, Durant M, Chennamadhavuni S, Wu H, Gray N, Melnick A. Abstract LB-303: Substrate-mimetic covalent inhibitor of MALT1 is most effective against CARD11 mutant ABC-DLBCL Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-303  0.711
2015 Yeo AT, Chennamadhavuni S, Whitty A, Porco JA, Gilmore TD. Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines. Molecules (Basel, Switzerland). 20: 7474-94. PMID 25915462 DOI: 10.3390/Molecules20057474  0.604
2014 Villar EA, Beglov D, Chennamadhavuni S, Porco JA, Kozakov D, Vajda S, Whitty A. How proteins bind macrocycles. Nature Chemical Biology. 10: 723-31. PMID 25038790 DOI: 10.1038/Nchembio.1584  0.536
2013 Chepiga KM, Qin C, Alford JS, Chennamadhavuni S, Gregg TM, Olson JP, Davies HM. Guide to Enantioselective Dirhodium(II)-Catalyzed Cyclopropanation with Aryldiazoacetates. Tetrahedron. 69. PMID 24273349 DOI: 10.1016/J.Tet.2013.04.075  0.62
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