Roger Brent - Publications

Affiliations: 
Biology Fred Hutch Cancer Research Center 

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Pesce CG, Zdraljevic S, Peria WJ, Bush A, Repetto MV, Rockwell D, Yu RC, Colman-Lerner A, Brent R. Single-cell profiling screen identifies microtubule-dependent reduction of variability in signaling. Molecular Systems Biology. 14: e7390. PMID 29618636 DOI: 10.15252/Msb.20167390  0.685
2016 Andrews SS, Peria WJ, Yu RC, Colman-Lerner A, Brent R. Push-Pull and Feedback Mechanisms Can Align Signaling System Outputs with Inputs. Cell Systems. 3: 444-455.e2. PMID 27894998 DOI: 10.1016/J.Cels.2016.10.002  0.621
2013 Pincus D, Ryan CJ, Smith RD, Brent R, Resnekov O. Assigning quantitative function to post-translational modifications reveals multiple sites of phosphorylation that tune yeast pheromone signaling output. Plos One. 8: e56544. PMID 23554854 DOI: 10.1371/Journal.Pone.0056544  0.362
2011 Golemis EA, Serebriiskii I, Finley RL, Kolonin MG, Gyuris J, Brent R. Interaction trap/two-hybrid system to identify interacting proteins. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 17.3.. PMID 22161546 DOI: 10.1002/0471143030.Cb1703S53  0.357
2011 Thomson TM, Benjamin KR, Bush A, Love T, Pincus D, Resnekov O, Yu RC, Gordon A, Colman-Lerner A, Endy D, Brent R. Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range. Proceedings of the National Academy of Sciences of the United States of America. 108: 20265-70. PMID 22114196 DOI: 10.1073/Pnas.1004042108  0.669
2010 Andrews SS, Addy NJ, Brent R, Arkin AP. Detailed simulations of cell biology with Smoldyn 2.1. Plos Computational Biology. 6: e1000705. PMID 20300644 DOI: 10.1371/Journal.Pcbi.1000705  0.335
2009 Golemis EA, Serebriiskii I, Finley RL, Kolonin MG, Gyuris J, Brent R. Interaction trap/two-hybrid system to identify interacting proteins. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit19.2. PMID 19688737 DOI: 10.1002/0471140864.Ps1902S57  0.357
2008 Yu RC, Pesce CG, Colman-Lerner A, Lok L, Pincus D, Serra E, Holl M, Benjamin K, Gordon A, Brent R. Negative feedback that improves information transmission in yeast signalling. Nature. 456: 755-61. PMID 19079053 DOI: 10.1038/Nature07513  0.694
2008 Yu RC, Resnekov O, Abola AP, Andrews SS, Benjamin KR, Bruck J, Burbulis IE, Colman-Lerner A, Endy D, Gordon A, Holl M, Lok L, Pesce CG, Serra E, Smith RD, ... ... Brent R, et al. The Alpha Project: a model system for systems biology research. Iet Systems Biology. 2: 222-33. PMID 19045818 DOI: 10.1049/iet-syb:20080127  0.441
2008 Engebrecht J, Brent R, Kaderbhai MA. Minipreps of plasmid DNA. Current Protocols in Molecular Biology. Unit1.6. PMID 18265045 DOI: 10.1002/0471142727.Mb0106S15  0.313
2007 Burbulis I, Yamaguchi K, Yu R, Resnekov O, Brent R. Quantifying small numbers of antibodies with a 'near-universal' protein-DNA chimera. Nature Methods. 4: 1011-3. PMID 17982460 DOI: 10.1038/Nmeth1127  0.64
2007 Gordon A, Colman-Lerner A, Chin TE, Benjamin KR, Yu RC, Brent R. Single-cell quantification of molecules and rates using open-source microscope-based cytometry. Nature Methods. 4: 175-81. PMID 17237792 DOI: 10.1038/Nmeth1008  0.647
2006 Colman-Lerner A, Gordon A, Serra E, Chin T, Resnekov O, Endy D, Pesce CG, Brent R. Erratum: Regulated cell-to-cell variation in a cell-fate decision system Nature. 439: 502-502. DOI: 10.1038/Nature04476  0.491
2005 Colman-Lerner A, Gordon A, Serra E, Chin T, Resnekov O, Endy D, Pesce CG, Brent R. Regulated cell-to-cell variation in a cell-fate decision system. Nature. 437: 699-706. PMID 16170311 DOI: 10.1038/Nature03998  0.558
2005 Brent R, Lok L. Cell biology. A fishing buddy for hypothesis generators. Science (New York, N.Y.). 308: 504-6. PMID 15845840 DOI: 10.1126/Science.1110535  0.363
2005 Burbulis I, Yamaguchi K, Gordon A, Carlson R, Brent R. Using protein-DNA chimeras to detect and count small numbers of molecules. Nature Methods. 2: 31-7. PMID 15782158 DOI: 10.1038/Nmeth729  0.316
2001 Engebrecht J, Heilig JS, Brent R. Preparation of bacterial plasmid DNA. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 10.3. PMID 18432694 DOI: 10.1002/0471142735.Im1003S27  0.31
2001 Engebrecht J, Heilig JS, Brent R. Preparation of bacterial plasmid DNA. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Appendix 1J. PMID 18428441 DOI: 10.1002/0471142301.Nsa01Js10  0.31
2001 Heilig JS, Elbing KL, Brent R. Large-scale preparation of plasmid DNA. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit1.7. PMID 18265046 DOI: 10.1002/0471142727.Mb0107S41  0.307
2001 Colman-Lerner A, Chin TE, Brent R. Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates. Cell. 107: 739-750. PMID 11747810 DOI: 10.1016/S0092-8674(01)00596-7  0.332
2001 Elbing KL, Brent r. Molecular Biology Techniques Current Protocols in Protein Science. DOI: 10.1002/0471140864.Psa04S13  0.317
2000 Colas P, Cohen B, Ferrigno PK, Silver PA, Brent R. Targeted modification and transportation of cellular proteins Proceedings of the National Academy of Sciences of the United States of America. 97: 13720-13725. PMID 11106396 DOI: 10.1073/Pnas.97.25.13720  0.379
2000 Meroni G, Cairo S, Merla G, Messali S, Brent R, Ballabio A, Reymond A. Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway? Oncogene. 19: 3266-77. PMID 10918583 DOI: 10.1038/Sj.Onc.1203634  0.386
1999 Fabbrizio E, Le Cam L, Polanowska J, Kaczorek M, Lamb N, Brent R, Sardet C. Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity. Oncogene. 18: 4357-63. PMID 10439043 DOI: 10.1038/Sj.Onc.1202825  0.402
1999 Geyer CR, Colman-Lerner A, Brent R. “Mutagenesis” by peptide aptamers identifies genetic network members and pathway connections Proceedings of the National Academy of Sciences of the United States of America. 96: 8567-8572. PMID 10411916 DOI: 10.1073/Pnas.96.15.8567  0.359
1999 Mendelsohn AR, Brent R. Protein interaction methods--toward an endgame. Science (New York, N.Y.). 284: 1948-50. PMID 10400537 DOI: 10.1126/Science.284.5422.1948  0.354
1998 Brent R. Analysis of protein-protein interactions. Current Protocols in Protein Science. 14. PMID 18429143 DOI: 10.1002/0471140864.Ps1901S14  0.346
1998 Cohen BA, Colas P, Brent R. An artificial cell-cycle inhibitor isolated from a combinatorial library Proceedings of the National Academy of Sciences of the United States of America. 95: 14272-14277. PMID 9826690 DOI: 10.1073/Pnas.95.24.14272  0.358
1998 Marti F, Xu CW, Selvakumar A, Brent R, Dupont B, King PD. LCK-phosphorylated human killer cell-inhibitory receptors recruit and activate phosphatidylinositol 3-kinase. Proceedings of the National Academy of Sciences of the United States of America. 95: 11810-5. PMID 9751747 DOI: 10.1073/Pnas.95.20.11810  0.323
1998 Colas P, Brent R. The impact of two-hybrid and related methods on biotechnology Trends in Biotechnology. 16: 355-363. PMID 9720324 DOI: 10.1016/S0167-7799(98)01225-6  0.335
1998 Mendelsohn AR, Brent R. Postgenomic protein analysis: the next bend in the river. Nature Biotechnology. 16: 520-1. PMID 9624679 DOI: 10.1038/Nbt0698-520  0.322
1997 Brent R, Finley RL. Understanding gene and allele function with two-hybrid methods Annual Review of Genetics. 31: 663-704. PMID 9442911 DOI: 10.1146/Annurev.Genet.31.1.663  0.353
1997 Meroni G, Reymond A, Alcalay M, Borsani G, Tanigami A, Tonlorenzi R, Lo Nigro C, Messali S, Zollo M, Ledbetter DH, Brent R, Ballabio A, Carrozzo R. Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor. The Embo Journal. 16: 2892-906. PMID 9184233 DOI: 10.1093/Emboj/16.10.2892  0.405
1996 Finley RL, Thomas BJ, Zipursky SL, Brent R. Isolation of Drosophila cyclin D, a protein expressed in the morphogenetic furrow before entry into S phase. Proceedings of the National Academy of Sciences of the United States of America. 93: 3011-5. PMID 8610160 DOI: 10.1073/Pnas.93.7.3011  0.354
1996 Colas P, Cohen B, Jessen T, Grishina I, McCoy J, Brent R. Genetic selection of peptide aptamers that recognize and inhibit cyclin-dependent kinase 2 Nature. 380: 548-550. PMID 8606778 DOI: 10.1038/380548A0  0.326
1995 Clemens KE, Brent R, Gyuris J, Munger K. Dimerization of the human papillomavirus E7 oncoprotein in vivo Virology. 214: 289-293. PMID 8525630 DOI: 10.1006/Viro.1995.9926  0.305
1995 Lee JW, Choi HS, Gyuris J, Brent R, Moore DD. Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor. Molecular Endocrinology (Baltimore, Md.). 9: 243-54. PMID 7776974 DOI: 10.1210/Mend.9.2.7776974  0.364
1995 Khazak V, Sadhale PP, Woychik NA, Brent R, Golemis EA. Human RNA polymerase II subunit hsRPB7 functions in yeast and influences stress survival and cell morphology. Molecular Biology of the Cell. 6: 759-75. PMID 7579693 DOI: 10.1091/Mbc.6.7.759  0.303
1995 Estojak J, Brent R, Golemis EA. Correlation of two-hybrid affinity data with in vitro measurements. Molecular and Cellular Biology. 15: 5820-9. PMID 7565735 DOI: 10.1128/Mcb.15.10.5820  0.353
1995 Zervos AS, Faccio L, Gatto JP, Kyriakis JM, Brent R. Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein Proceedings of the National Academy of Sciences of the United States of America. 92: 10531-10534. PMID 7479834 DOI: 10.1073/Pnas.92.23.10531  0.372
1994 Cuomo CA, Kirch SA, Gyuris J, Brent R, Oettinger MA. Rch1, a protein that specifically interacts with the RAG-1 recombination-activating protein. Proceedings of the National Academy of Sciences of the United States of America. 91: 6156-60. PMID 8016130 DOI: 10.1073/Pnas.91.13.6156  0.394
1994 Paroush Z, Finley RL, Kidd T, Wainwright SM, Ingham PW, Brent R, Ish-Horowicz D. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell. 79: 805-15. PMID 8001118 DOI: 10.1016/0092-8674(94)90070-1  0.375
1994 Hanes SD, Riddihough G, Ish-Horowicz D, Brent R. Specific DNA recognition and intersite spacing are critical for action of the bicoid morphogen. Molecular and Cellular Biology. 14: 3364-75. PMID 7909358 DOI: 10.1128/Mcb.14.5.3364  0.349
1994 Finley RL, Brent R. Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators Proceedings of the National Academy of Sciences of the United States of America. 91: 12980-12984. PMID 7809159 DOI: 10.1073/Pnas.91.26.12980  0.38
1994 Mendelsohn AR, Brent R. Applications of interaction traps/two-hybrid systems to biotechnology research. Current Opinion in Biotechnology. 5: 482-6. PMID 7765460 DOI: 10.1016/0958-1669(94)90061-2  0.368
1993 Zervos AS, Gyuris J, Brent R. Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites Cell. 72: 223-232. PMID 8425219 DOI: 10.1016/0092-8674(93)90662-A  0.373
1993 Gyuris J, Golemis E, Chertkov H, Brent R. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell. 75: 791-803. PMID 8242750 DOI: 10.1016/0092-8674(93)90498-F  0.362
1992 Golemis EA, Brent R. Fused protein domains inhibit DNA binding by LexA. Molecular and Cellular Biology. 12: 3006-14. PMID 1620111 DOI: 10.1128/Mcb.12.7.3006  0.356
1991 Hanes SD, Brent R. A genetic model for interaction of the homeodomain recognition helix with DNA. Science (New York, N.Y.). 251: 426-30. PMID 1671176 DOI: 10.1126/Science.1671176  0.364
1990 Kamens J, Richardson P, Mosialos G, Brent R, Gilmore T. Oncogenic transformation by vrel requires an amino-terminal activation domain. Molecular and Cellular Biology. 10: 2840-2847. PMID 2111443 DOI: 10.1128/Mcb.10.6.2840  0.328
1989 Samson ML, Jackson-Grusby L, Brent R. Gene activation and DNA binding by Drosophila Ubx and abd-A proteins. Cell. 57: 1045-52. PMID 2567633 DOI: 10.1016/0092-8674(89)90342-5  0.4
1989 Hanes SD, Brent R. DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9. Cell. 57: 1275-83. PMID 2500253 DOI: 10.1016/0092-8674(89)90063-9  0.387
1988 Lech K, Anderson K, Brent R. DNA-bound Fos proteins activate transcription in yeast Cell. 52: 179-184. PMID 3124961 DOI: 10.1016/0092-8674(88)90506-5  0.395
1986 Silver PA, Brent R, Ptashne M. DNA binding is not sufficient for nuclear localization of regulatory proteins in Saccharomyces cerevisiae. Molecular and Cellular Biology. 6: 4763-6. PMID 3099172 DOI: 10.1128/Mcb.6.12.4763  0.365
1985 Brent R, Ptashne M. A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor Cell. 43: 729-736. PMID 3907859 DOI: 10.1016/0092-8674(85)90246-6  0.37
1984 Brent R, Ptashne M. A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene Nature. 312: 612-615. PMID 6390216 DOI: 10.1038/312612A0  0.32
1982 Kenyon CJ, Brent R, Ptashne M, Walker GC. Regulation of damage-inducible genes in Escherichia coli Journal of Molecular Biology. 160: 445-457. PMID 6818350 DOI: 10.1016/0022-2836(82)90307-2  0.357
1981 Brent R, Ptashne M. Mechanism of action of the lexA gene product Proceedings of the National Academy of Sciences of the United States of America. 78: 4204-4208. PMID 7027256 DOI: 10.1073/Pnas.78.7.4204  0.376
1980 Brent R, Ptashne M. The lexA gene product represses its own promoter Proceedings of the National Academy of Sciences of the United States of America. 77: 1932-1936. PMID 6990417 DOI: 10.1073/Pnas.77.4.1932  0.344
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