Christopher Y Park - Publications

Affiliations: 
2004-2009 Pathology New York University School of Medicine, New York, NY, United States 
Area:
Hematopathology
Website:
https://nyulangone.org/doctors/1386786317/christopher-y-park

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Chakraborty S, Park CY. Pathogenic Mechanisms in Acute Myeloid Leukemia. Current Treatment Options in Oncology. PMID 36190670 DOI: 10.1007/s11864-022-01021-8  0.339
2022 Stranahan AW, Berezniuk I, Chakraborty S, Feller F, Khalaj M, Park CY. Leukotrienes promote stem cell self-renewal and chemoresistance in acute myeloid leukemia. Leukemia. PMID 35461365 DOI: 10.1038/s41375-022-01579-0  0.797
2021 Zhan D, Park CY. Stem Cells in the Myelodysplastic Syndromes. Frontiers in Aging. 2: 719010. PMID 35822030 DOI: 10.3389/fragi.2021.719010  0.325
2020 Spevak CC, Elias HK, Kannan L, Ali MAE, Martin GH, Selvaraj S, Eng WS, Ernlund A, Rajasekhar VK, Woolthuis CM, Zhao G, Ha CJ, Schneider RJ, Park CY. Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms. Cell Stem Cell. 26: 755-765.e7. PMID 32386556 DOI: 10.1016/J.Stem.2019.12.006  0.435
2020 Ramalingam P, Poulos MG, Lazzari E, Gutkin MC, Lopez D, Kloss CC, Crowley MJ, Katsnelson L, Freire AG, Greenblatt MB, Park CY, Butler JM. Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF. Nature Communications. 11: 666. PMID 32015345 DOI: 10.1038/S41467-020-14478-8  0.373
2019 Guillamot M, Ouazia D, Dolgalev I, Yeung ST, Kourtis N, Dai Y, Corrigan K, Zea-Redondo L, Saraf A, Florens L, Washburn MP, Tikhonova AN, Malumbres M, Gong Y, Tsirigos A, ... Park C, et al. The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation. Nature Immunology. PMID 31406379 DOI: 10.1038/S41590-019-0454-6  0.362
2019 Martin GH, Roy N, Chakraborty S, Desrichard A, Chung SS, Woolthuis CM, Hu W, Berezniuk I, Garrett-Bakelman FE, Hamann J, Devlin SM, Chan TA, Park CY. CD97 is a critical regulator of acute myeloid leukemia stem cell function. The Journal of Experimental Medicine. PMID 31371381 DOI: 10.1084/Jem.20190598  0.492
2019 Del Rey Gonzalez M, Park CY. Deconstructing myelodysplastic syndromes. Blood. 134: 106-107. PMID 31296543 DOI: 10.1182/Blood.2019001179  0.396
2019 Spevak CC, Park CY. Novel Mechanism Regulates c-Myc Expression in Diffuse Large B-cell Lymphoma. Journal of the National Cancer Institute. PMID 31114884 DOI: 10.1093/Jnci/Djz104  0.308
2019 Pang WW, Czechowicz A, Logan AC, Bhardwaj R, Poyser J, Park CY, Weissman IL, Shizuru JA. Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice. Blood. PMID 30745302 DOI: 10.1182/Blood-2018-06-858159  0.828
2019 Ha CJ, Hu W, Elias HK, Chakraborty S, Park CY. Mir-29 Maintains the Acute Myeloid Leukemia Epigenome By Regulating CBX2 Blood. 134: 1236-1236. DOI: 10.1182/Blood-2019-131518  0.454
2019 Elias HK, Spevak C, Kannan L, Ali MA, Martin GH, Selvaraj S, Eng WS, Zhao G, Ernlund A, Rajasekhar V, Woolthuis CM, Schneider RJ, Park CY. Unique Regulatory Pathways Dictate the Translational Program in Hematopoietic Stem and Progenitor Cells Blood. 134: 1180-1180. DOI: 10.1182/Blood-2019-131333  0.37
2019 Elias HK, Shin JY, Ali MA, Chakraborty S, Ha CJ, Dolgalev I, Konishi C, Beerman I, Park CY. Identification of Old HSCs with Preserved Self-Renewal and Long-Term Reconstitution Potential Blood. 134: 2479-2479. DOI: 10.1182/Blood-2019-129508  0.346
2019 Park C, Martin G, Roy N, Chakraborty S, Desrichard A, chung S, Woolthuis C, Hu W, berezniuk I, Garrett-Bakelman F, Hamann J, Devlin s, chan T. 1018 - CD97 IS A CRITICAL REGULATOR OF ACUTE MYELOID LEUKEMIA STEM CELL FUNCTION Experimental Hematology. 76: S31. DOI: 10.1016/J.Exphem.2019.06.256  0.512
2018 Tavakkoli M, Chung SS, Park CY. Do preclinical studies suggest that CD99 is a potential therapeutic target in acute myeloid leukemia and the myelodysplastic syndromes? Expert Opinion On Therapeutic Targets. PMID 29637789 DOI: 10.1080/14728222.2018.1464140  0.547
2018 Martin GH, Park CY. Meddling with METTLs in Normal and Leukemia Stem Cells. Cell Stem Cell. 22: 139-141. PMID 29395048 DOI: 10.1016/J.Stem.2018.01.013  0.469
2018 Spevak C, Elias H, Kannan L, Martin G, Selvaraj S, Eng W, Ernlund A, Rajasekhar V, Woolthuis C, Schneider R, Park CY. Mtor-Independent Translation in Early Hematopoietic Development Blood. 132: 3827-3827. DOI: 10.1182/Blood-2018-99-120191  0.352
2018 Chung S, Hu W, Guo L, Park C. CD99 Regulates Normal and Malignant Hematopoietic Stem Cell Function by Restricting Protein Translation Experimental Hematology. 64: S58-S59. DOI: 10.1016/J.Exphem.2018.06.203  0.512
2018 Pang WW, Czechowicz A, Poyser J, Park CY, Weissman IL, Shizuru JA. Anti-Human CD117 Antibodies Mediate Clearance of Myelodysplastic Syndrome Hematopoietic Stem Cells and Facilitate Establishment of Normal Hematopoiesis in Transplantation Biology of Blood and Marrow Transplantation. 24: S230-S231. DOI: 10.1016/J.Bbmt.2017.12.211  0.823
2017 Chung SS, Park CY. Aging, hematopoiesis, and the myelodysplastic syndromes. Blood Advances. 1: 2572-2578. PMID 29296910 DOI: 10.1182/Bloodadvances.2017009852  0.385
2017 Chung SS, Park CY. Aging, hematopoiesis, and the myelodysplastic syndromes. Hematology. American Society of Hematology. Education Program. 2017: 73-78. PMID 29222239 DOI: 10.1182/Asheducation-2017.1.73  0.385
2017 Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, Ng V, Xia B, Witkowski MT, Mitchell-Flack M, Grillo I, Bakogianni S, Ndiaye-Lobry D, Martín MT, Guillamot M, ... ... Park CY, et al. Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. Cell. PMID 28823558 DOI: 10.1016/J.Cell.2017.07.032  0.439
2017 Khalaj M, Woolthuis CM, Hu W, Durham BH, Chu SH, Qamar S, Armstrong SA, Park CY. miR-99 regulates normal and malignant hematopoietic stem cell self-renewal. The Journal of Experimental Medicine. PMID 28733386 DOI: 10.1084/Jem.20161595  0.797
2017 Khalaj M, Park CY. snoRNAs contribute to myeloid leukaemogenesis. Nature Cell Biology. 19: 758-760. PMID 28659642 DOI: 10.1038/Ncb3566  0.763
2017 Martin GH, Park CY. EPCR: a novel marker of cultured cord blood HSCs. Blood. 129: 3279-3280. PMID 28642358 DOI: 10.1182/Blood-2017-05-780007  0.37
2017 Durham BH, Roos-Weil D, Baillou C, Cohen-Aubart F, Yoshimi A, Miyara M, Papo M, Hélias-Rodzewicz Z, Terrones N, Ozkaya N, Dogan A, Rampal R, Urbain F, Le Fèvre L, Diamond EL, ... Park CY, et al. Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells. Blood. PMID 28566492 DOI: 10.1182/Blood-2016-12-757377  0.49
2017 Chung SS, Eng WS, Hu W, Khalaj M, Garrett-Bakelman FE, Tavakkoli M, Levine RL, Carroll M, Klimek VM, Melnick AM, Park CY. CD99 is a therapeutic target on disease stem cells in myeloid malignancies. Science Translational Medicine. 9. PMID 28123069 DOI: 10.1126/Scitranslmed.Aaj2025  0.833
2017 Elias HK, Bryder D, Park CY. Molecular mechanisms underlying lineage bias in aging hematopoiesis. Seminars in Hematology. 54: 4-11. PMID 28088987 DOI: 10.1053/J.Seminhematol.2016.11.002  0.661
2017 Chung S, Vijay P, Klimek V, Mason C, Park C. An Analysis of the Transcriptional Response of Myelodysplastic Syndrome Stem Cells to Therapy at Single-Cell Resolution Leukemia Research. 55: S6-S7. DOI: 10.1182/Blood.V128.22.960.960  0.444
2017 Chung S, Vijay P, Klimek V, Mason C, Park C. An analysis of the transcriptional response of myelodysplastic syndrome stem cells to therapy at single-cell resolution Experimental Hematology. 53: S115. DOI: 10.1016/J.Exphem.2017.06.287  0.427
2016 Elias HK, Khalaj M, Park CY. Divergent roles of in normal and malignant stem cells. Translational Cancer Research. 5: S328-S331. PMID 33088733 DOI: 10.21037/tcr.2016.07.15  0.804
2016 Xu H, Valerio DG, Eisold ME, Sinha A, Koche RP, Hu W, Chen CW, Chu SH, Brien GL, Park CY, Hsieh JJ, Ernst P, Armstrong SA. NUP98 Fusion Proteins Interact with the NSL and MLL1 Complexes to Drive Leukemogenesis. Cancer Cell. PMID 27889185 DOI: 10.1016/J.Ccell.2016.10.019  0.313
2016 Ye H, Adane B, Khan N, Sullivan T, Minhajuddin M, Gasparetto M, Stevens B, Pei S, Balys M, Ashton JM, Klemm DJ, Woolthuis CM, Stranahan AW, Park CY, Jordan CT. Leukemic Stem Cells Evade Chemotherapy by Metabolic Adaptation to an Adipose Tissue Niche. Cell Stem Cell. PMID 27374788 DOI: 10.1016/J.Stem.2016.06.001  0.475
2016 Li S, Garrett-Bakelman FE, Chung SS, Sanders MA, Hricik T, Rapaport F, Patel J, Dillon R, Vijay P, Brown AL, Perl AE, Cannon J, Bullinger L, Luger S, Becker M, ... ... Park CY, et al. Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia. Nature Medicine. PMID 27322744 DOI: 10.1038/Nm.4125  0.31
2016 Woolthuis CM, Park CY. Hematopoietic stem/progenitor cell commitment to the megakaryocyte lineage. Blood. PMID 26787736 DOI: 10.1182/Blood-2015-07-607945  0.439
2016 Elias HK, Khalaj M, Park CY. Divergent roles of miR-126 in normal and malignant stem cells Translational Cancer Research. 5. DOI: 10.21037/8804  0.819
2016 Durham BH, Yoshimi A, Papo M, Chung YR, Ozkaya N, Ganzel C, Dogan A, Hyman DM, Park CY, Rampal RK, Roos Weil D, Lemoine FM, Amoura Z, Bernard OA, Diamond EL, et al. Frequent Clinical Overlap of Histiocytic Neoplasms and WHO-Classified Myeloid Malignancies Leads to Functional Insights into the Cell-of-Origin of Histiocytoses Blood. 128: 951-951. DOI: 10.1182/Blood.V128.22.951.951  0.414
2016 Rapaport F, de Massy MR, al Hinai A, Sanders MA, Hricik T, Sheridan C, Lee TC, Neelamraju Y, Patel J, Chung SS, Becker MW, Lewis ID, D'Andrea R, Bullinger L, Döhner K, ... ... Park CY, et al. Changes of the Mutational Landscape in Relapsed Acute Myeloid Leukemia Blood. 128: 599-599. DOI: 10.1182/Blood.V128.22.599.599  0.311
2016 Samaraweera SE, Garrett-Bakelman FE, Neelamraju Y, Perugini M, Casolari DA, Iarossi D, Bray SC, Sheridan C, Lee TC, Tiong IS, Danner S, Cummings N, Guzman ML, Roboz GJ, To LB, ... ... Park CY, et al. Hypermethylation of GADD45A Defines a Methylation Profile Distinct to Mutant IDH1/2, and Correlates with More Aggressive AML Blood. 128: 2877-2877. DOI: 10.1182/Blood.V128.22.2877.2877  0.312
2016 Khalaj M, Woolthuis C, Hu W, Durham BH, Park CY. Mir-99 Regulates Normal and Leukemic Stem Cell Function Blood. 128: 1469-1469. DOI: 10.1182/Blood.V128.22.1469.1469  0.791
2015 Mulero-Navarro S, Sevilla A, Roman AC, Lee DF, D'Souza SL, Pardo S, Riess I, Su J, Cohen N, Schaniel C, Rodriguez NA, Baccarini A, Brown BD, Cavé H, Caye A, ... ... Park CY, et al. Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia. Cell Reports. 13: 504-515. PMID 26456833 DOI: 10.1016/J.Celrep.2015.09.019  0.45
2015 Ke S, Alemu EA, Mertens C, Gantman EC, Fak JJ, Mele A, Haripal B, Zucker-Scharff I, Moore MJ, Park CY, Vågbø CB, Kuśnierczyk A, Klungland A, Darnell JE, Darnell RB. A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes & Development. PMID 26404942 DOI: 10.1101/Gad.269415.115  0.387
2015 Tiacci E, Park JH, De Carolis L, Chung SS, Broccoli A, Scott S, Zaja F, Devlin S, Pulsoni A, Chung YR, Cimminiello M, Kim E, Rossi D, Stone RM, Motta G, ... ... Park CY, et al. Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia. The New England Journal of Medicine. PMID 26352686 DOI: 10.1056/Nejmoa1506583  0.353
2015 Raval A, Behbehani GK, Nguyen le XT, Thomas D, Kusler B, Garbuzov A, Ramunas J, Holbrook C, Park CY, Blau H, Nolan GP, Artandi SE, Mitchell BS. Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice. Plos One. 10: e0131722. PMID 26133370 DOI: 10.1371/Journal.Pone.0131722  0.449
2015 Hu W, Dooley J, Chung SS, Chandramohan D, Cimmino L, Mukherjee S, Mason CE, de Strooper B, Liston A, Park CY. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 125: 2206-16. PMID 25634742 DOI: 10.1182/Blood-2014-06-585273  0.375
2015 Poulos MG, Gutkin M, Park CY, Butler JM. Rejuvenation of Aged Vascular Niches to Enhance Hematopoietic Function Blood. 126: 781-781. DOI: 10.1182/Blood.V126.23.781.781  0.422
2015 Chung SS, Vijay P, Stern DL, O'Sullivan D, Klimek VM, Mason C, Park CY. Analysis of Myelodysplastic Syndrome Stem Cells at Single Cell Resolution during DNA Methyltransferase Inhibitor Therapy Blood. 126: 4101-4101. DOI: 10.1182/Blood.V126.23.4101.4101  0.411
2015 Khalaj M, Hu W, Park CY. Mir-99 Is a Regulator of Hematopoietic and Leukemic Stem Cell Differentiation Blood. 126: 3063-3063. DOI: 10.1182/Blood.V126.23.3063.3063  0.802
2015 Garrett-Bakelman FE, Li S, Chung SS, Hricik T, Franck R, Patel J, Dillon R, Vijay P, Brown AL, Perl AE, Cannon BJ, Sanders MA, Valk PJM, Bullinger L, Luger S, ... ... Park CY, et al. Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia Blood. 126: 306-306. DOI: 10.1182/Blood.V126.23.306.306  0.335
2015 Tavakkoli M, Lee DH, Durham B, Chung SS, Park CY. Targeting CD99 in T-Cell Neoplasms with Monoclonal Antibodies Blood. 126: 2749-2749. DOI: 10.1182/Blood.V126.23.2749.2749  0.458
2015 Hu W, Park CY. Desuppressed Expressionsof MiR-29 targetsdisturb the Leukemeugenesis of MLL-AF9 Blood. 126: 1228-1228. DOI: 10.1182/Blood.V126.23.1228.1228  0.396
2015 Tavakkoli M, Lee DH, Chung SS, Park CY. Abstract 3566: Targeting CD99 in T-cell neoplasms Cancer Research. 75: 3566-3566. DOI: 10.1158/1538-7445.Am2015-3566  0.435
2015 Park CY, Vijay P, Chung SS, Stern D, Klimek V, Mason CE. Declined presentation single-cell analysis of myelodysplastic sydrome stem cells during therapy and disease progression Experimental Hematology. 43: S88. DOI: 10.1016/J.Exphem.2015.06.224  0.425
2014 Rampal R, Ahn J, Abdel-Wahab O, Nahas M, Wang K, Lipson D, Otto GA, Yelensky R, Hricik T, McKenney AS, Chiosis G, Chung YR, Pandey S, van den Brink MR, Armstrong SA, ... ... Park CY, et al. Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms. Proceedings of the National Academy of Sciences of the United States of America. 111: E5401-10. PMID 25516983 DOI: 10.1073/Pnas.1407792111  0.365
2014 Abdel-Wahab O, Park CY. BRAF-mutant hematopoietic malignancies. Oncotarget. 5: 7980-1. PMID 25478626 DOI: 10.18632/Oncotarget.2448  0.441
2014 Khalaj M, Tavakkoli M, Stranahan AW, Park CY. Pathogenic microRNA's in myeloid malignancies. Frontiers in Genetics. 5: 361. PMID 25477897 DOI: 10.3389/Fgene.2014.00361  0.77
2014 Hu W, Park CY. Measuring microRNA expression in mouse hematopoietic stem cells. Methods in Molecular Biology (Clifton, N.J.). 1185: 121-40. PMID 25062625 DOI: 10.1007/978-1-4939-1133-2_8  0.359
2014 Khalaj M, Park CY. Notch one up to stroma: endothelial notch prevents inflammation and myeloproliferation. Cell Stem Cell. 15: 1-2. PMID 24996160 DOI: 10.1016/J.Stem.2014.06.010  0.793
2014 Chung SS, Kim E, Park JH, Chung YR, Lito P, Teruya-Feldstein J, Hu W, Beguelin W, Monette S, Duy C, Rampal R, Telis L, Patel M, Kim MK, Huberman K, ... ... Park CY, et al. Hematopoietic stem cell origin of BRAFV600E mutations in hairy cell leukemia. Science Translational Medicine. 6: 238ra71. PMID 24871132 DOI: 10.1126/Scitranslmed.3008004  0.483
2014 Shin JY, Hu W, Naramura M, Park CY. High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias. The Journal of Experimental Medicine. 211: 217-31. PMID 24446491 DOI: 10.1084/Jem.20131128  0.325
2014 Yoo M, Lee GA, Park C, Cohen RI, Schachner M. Analysis of human embryonic stem cells with regulatable expression of the cell adhesion molecule l1 in regeneration after spinal cord injury. Journal of Neurotrauma. 31: 553-64. PMID 24125017 DOI: 10.1089/neu.2013.2886  0.305
2014 Perugini M, Samaraweera SE, Brown AL, Cummings N, Danner S, Tiong IS, Garrett-Bakelman FE, Carroll MP, Becker MW, Chung SS, Park CY, Mason CE, Guzman ML, Levine RL, Melnick AM, et al. The Significance of GADD45A Promoter DNA Hypermethylation in AML: Association with IDH1/2 and TET2 Mutation Blood. 124: 69-69. DOI: 10.1182/Blood.V124.21.69.69  0.326
2014 Yalcin S, Carty M, Shin JY, Miller RA, Leslie C, Park CY. Microrna Mediated Regulation of Hematopoietic Stem Cell Aging Blood. 124: 602-602. DOI: 10.1182/Blood.V124.21.602.602  0.473
2014 Hu W, Dooley J, Cimmino L, Liston A, Park CY. MiR-29a is Essential in Leukemic Transformation and Maintaining Hematopoietic Stem Cell Self-Renewal Blood. 124: 4792-4792. DOI: 10.1182/Blood.V124.21.4792.4792  0.374
2014 Chung SS, Tavakkoli M, Klimek VM, Park CY. CD99 Is a Therapeutic Target on Disease Initiating Stem Cells in Acute Myeloid Leukemia and the Myelodysplastic Syndromes Blood. 124: 3760-3760. DOI: 10.1182/BLOOD.V124.21.3760.3760  0.393
2014 Kim E, Chung SS, Park JH, Chung YR, Lito P, Feldstein J, Hu W, Beguilin W, Monette S, Duy C, Rampal R, Telis L, Patel M, Kim MK, Melnick AM, ... ... Park CY, et al. Abstract 3140: Context specific effects of the BRAFV600E mutation on hematopoiesis identifies novel models of BRAF mutant hematopoietic disorders Cancer Research. 74: 3140-3140. DOI: 10.1158/1538-7445.Am2014-3140  0.454
2014 Chung S, Kim E, Park J, Chung YR, Tallman M, Abdel-Wahab O, Park C. BRAFV600E mutations occur in hematopoietic stem cells in hairy cell leukemia Experimental Hematology. 42: S29. DOI: 10.1016/J.Exphem.2014.07.102  0.45
2014 Park C, Yalcin S, Carty M, Shin J, Miller R, Leslie C. Anti-aging interventions reverse hematopoietic stem cell aging via regulation of micrornas Experimental Hematology. 42: S21. DOI: 10.1016/J.Exphem.2014.07.074  0.388
2014 Chung S, Klimek V, Park C. CD99 is a therapeutic target on disease stem cells in acute myeloid leukemia and the myelodysplastic syndromes Experimental Hematology. 42: S20. DOI: 10.1016/J.Exphem.2014.07.071  0.491
2014 Chung SS, Devlin S, Park CY. CD99 Identifies Disease Stem Cells in Acute Myeloid Leukemia (AML) and the Myelodysplastic Syndromes (MDS) Clinical Lymphoma Myeloma and Leukemia. 14: S121. DOI: 10.1016/J.Clml.2014.06.041  0.499
2014 Yalcin S, Chung SS, Park CY. The role of MicroRNAs in hematopoietic stem cells and leukemia development Microrna in Development and in the Progression of Cancer. 139-157. DOI: 10.1007/978-1-4899-8065-6_8  0.381
2014 Chung SS, Park CY. Acute Myeloid Leukemia Stem Cells-Updates and Controversies Cancer Stem Cells. 143-160. DOI: 10.1002/9781118356203.ch11  0.358
2013 Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, Kuscu C, Hricik T, Ndiaye-Lobry D, Lafave LM, Koche R, Shih AH, Guryanova OA, Kim E, Li S, ... ... Park CY, et al. Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo. The Journal of Experimental Medicine. 210: 2641-59. PMID 24218140 DOI: 10.1084/Jem.20131141  0.462
2013 Deshpande S, Bosbach B, Yozgat Y, Park CY, Moore MA, Besmer P. KIT receptor gain-of-function in hematopoiesis enhances stem cell self-renewal and promotes progenitor cell expansion. Stem Cells (Dayton, Ohio). 31: 1683-95. PMID 23681919 DOI: 10.1002/Stem.1419  0.43
2013 Pang WW, Pluvinage JV, Price EA, Sridhar K, Arber DA, Greenberg PL, Schrier SL, Park CY, Weissman IL. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes. Proceedings of the National Academy of Sciences of the United States of America. 110: 3011-6. PMID 23388639 DOI: 10.1073/Pnas.1222861110  0.812
2013 Lobry C, Ntziachristos P, Ndiaye-Lobry D, Oh P, Cimmino L, Zhu N, Araldi E, Hu W, Freund J, Abdel-Wahab O, Ibrahim S, Skokos D, Armstrong SA, Levine RL, Park CY, et al. Notch pathway activation targets AML-initiating cell homeostasis and differentiation. The Journal of Experimental Medicine. 210: 301-19. PMID 23359070 DOI: 10.1084/Jem.20121484  0.37
2013 Chung SS, Park JH, Kim E, Chung YR, Hu W, Lito P, Feldstein JT, Rampal RK, Telis L, Patel M, Rosen N, Park CY, Tallman MS, Abdel-Wahab O. BRAFV600E Mutations Occur In The Hematopoietic Stem Cell Compartment In Hairy Cell Leukemia Blood. 122: 816-816. DOI: 10.1182/Blood.V122.21.816.816  0.529
2013 Garrett-Bakelman FE, Li S, Hricik T, Chung SS, Bar H, Brown AL, Patel JP, Rapoport F, Liu L, Sheridan C, Ishii J, Zumbo P, Gandara J, Lewis ID, To LB, ... ... Park CY, et al. Epigenetic Deregulation In Relapsed Acute Myeloid Leukemia Blood. 122: 2499-2499. DOI: 10.1182/Blood.V122.21.2499.2499  0.338
2013 Hu W, Dooley J, Chung SS, Yalcin S, Shin YS, De Strooper B, Liston A, Park CY. MiR-29a Maintains Hematopoietic Stem Cell Self-Renewal and Is Required For Myeloid Leukemogenesis Blood. 122: 1190-1190. DOI: 10.1182/Blood.V122.21.1190.1190  0.379
2013 Yalcin S, Hu W, Miller RA, Shin Y, Park CY. Longevity Promoting Interventions Inhibit Molecular and Functional Changes In Aging Hematopoietic Stem Cells Blood. 122: 1168-1168. DOI: 10.1182/Blood.V122.21.1168.1168  0.379
2013 Park C, Pang W, Chung S, Pluvinage J, Price E, Sridhar K, Arber D, Greenberg P, Schrier S, Weissman I. O-009 Evaluation of hematopoietic stem/progenitor cells in MDS reveals novel pathogenic mechanisms Leukemia Research. 37: S12-S13. DOI: 10.1016/S0145-2126(13)70031-6  0.767
2013 Park C, Shin J, Yalcin S, Hu W. Low c-Kit expression identifies hematopoietic stem cells with enhanced self-renewal potential Experimental Hematology. 41: S43. DOI: 10.1016/J.Exphem.2013.05.171  0.429
2013 Park C, Hu W, Dooley J, Chung S, Shin YS, De Strooper B, Liston A. miR-29a maintains hematopoietic stem cell self-renewal and is required for leukemic transformation Experimental Hematology. 41: S43. DOI: 10.1016/J.Exphem.2013.05.170  0.415
2013 Chung S, Pang W, Jan M, Klimek V, Weissman I, Majeti R, Park C. CD99 identifies disease stem cells in acute myeloid leukemia (AML) and the myelodysplastic syndromes (MDS) Experimental Hematology. 41: S16. DOI: 10.1016/J.Exphem.2013.05.060  0.83
2012 Kim D, Park CY, Medeiros BC, Weissman IL. CD19-CD45 low/- CD38 high/CD138+ plasma cells enrich for human tumorigenic myeloma cells. Leukemia. 26: 2530-7. PMID 22733078 DOI: 10.1038/Leu.2012.140  0.631
2012 Raval A, Kusler B, Pang WW, Weissman IL, Mitchell BS, Park CY. Effect of nucleophosmin1 haploinsufficiency on hematopoietic stem cells. Leukemia. 26: 853-5. PMID 21979879 DOI: 10.1038/Leu.2011.270  0.774
2012 Rampal RK, Pandey S, Abdel-Wahab O, Tsai JJ, Manshouri T, Park CY, Verstovsek S, Levine RL. Development of a Murine Model for Leukemic Transformation of Myeloproliferative Neoplasms for Preclinical Therapeutic Studies Blood. 120: 808-808. DOI: 10.1182/Blood.V120.21.808.808  0.416
2012 Levine RL, Koppikar P, Marubayashi S, Bhagwat N, Taldone T, Park CY, Chiosis G. Combination Therapy Using JAK2 and HSP90 Inhibitors Increased Efficacy in Myelofibrosis in Vivo Blood. 120: 805-805. DOI: 10.1182/Blood.V120.21.805.805  0.305
2012 Abdel-Wahab O, Gao J, Adli M, Chung YR, Koche R, Shih AH, Pandey S, La-Fave LM, Ndiaye-Lobry D, Shin YS, Bhatt PK, Patel JP, Zhao X, Park CY, Jaffe JD, et al. Conditional Deletion of Asxl1 Results in Myelodysplasia Blood. 120: 308-308. DOI: 10.1182/Blood.V120.21.308.308  0.361
2012 Shin JY, Hu W, Park CY. Differential Expression of c-Kit Identifies Hematopoietic Stem Cells with Variable Self-Renewal Potential. Blood. 120: 2325-2325. DOI: 10.1182/Blood.V120.21.2325.2325  0.375
2012 Chung SS, Pang WW, In GK, Jan M, Klimek VM, Melnick A, Weissman IL, Majeti R, Park CY. CD99 Identifies Disease Stem Cells in Acute Myeloid Leukemia and the Myelodysplastic Syndromes Blood. 120: 210-210. DOI: 10.1182/Blood.V120.21.210.210  0.8
2011 Chung SS, Hu W, Park CY. The Role of MicroRNAs in Hematopoietic Stem Cell and Leukemic Stem Cell Function. Therapeutic Advances in Hematology. 2: 317-34. PMID 23556099 DOI: 10.1177/2040620711410772  0.479
2011 Amrani YM, Gill J, Matevossian A, Alonzo ES, Yang C, Shieh JH, Moore MA, Park CY, Sant'Angelo DB, Denzin LK. The Paf oncogene is essential for hematopoietic stem cell function and development. The Journal of Experimental Medicine. 208: 1757-65. PMID 21844206 DOI: 10.1084/Jem.20102170  0.461
2011 McGowan KA, Pang WW, Bhardwaj R, Perez MG, Pluvinage JV, Glader BE, Malek R, Mendrysa SM, Weissman IL, Park CY, Barsh GS. Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome. Blood. 118: 3622-33. PMID 21788341 DOI: 10.1182/Blood-2010-11-318584  0.742
2011 Chao MP, Alizadeh AA, Tang C, Jan M, Weissman-Tsukamoto R, Zhao F, Park CY, Weissman IL, Majeti R. Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia. Cancer Research. 71: 1374-84. PMID 21177380 DOI: 10.1158/0008-5472.Can-10-2238  0.726
2011 Park CY, Pang WW, Price E, Pluvinage JA, Schrier SL, Weissman IL. Hematopoietic Stem Cells Are the Disease-Initiating Cells in the Myelodysplastic Syndromes Blood. 118: 789-789. DOI: 10.1182/Blood.V118.21.789.789  0.812
2011 Hu W, Park CY. Leukemogenic MicroRNA-29a Causes Myeloproliferation by Inhibiting Apoptosis and Inducing Aberrant Self-Renewal in a Developmental Stage Specific Manner Blood. 118: 2556-2556. DOI: 10.1182/Blood.V118.21.2556.2556  0.422
2011 Czechowicz A, Bhardwaj R, Pang W, Park C, Weissman I. Targeted Clearance of Human Hematopoietic Stem Cell Niches Via Inhibition of SCF Signaling Using Monoclonal Antibody SR-1 Biology of Blood and Marrow Transplantation. 17: S187-S188. DOI: 10.1182/Blood.V116.21.74.74  0.826
2010 Chao MP, Jaiswal S, Weissman-Tsukamoto R, Alizadeh AA, Gentles AJ, Volkmer J, Weiskopf K, Willingham SB, Raveh T, Park CY, Majeti R, Weissman IL. Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47. Science Translational Medicine. 2: 63ra94. PMID 21178137 DOI: 10.1126/Scitranslmed.3001375  0.804
2010 Ooi AG, Sahoo D, Adorno M, Wang Y, Weissman IL, Park CY. MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. Proceedings of the National Academy of Sciences of the United States of America. 107: 21505-10. PMID 21118986 DOI: 10.1073/Pnas.1016218107  0.758
2010 Chao MP, Alizadeh AA, Tang C, Myklebust JH, Varghese B, Gill S, Jan M, Cha AC, Chan CK, Tan BT, Park CY, Zhao F, Kohrt HE, Malumbres R, Briones J, et al. Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma. Cell. 142: 699-713. PMID 20813259 DOI: 10.1016/J.Cell.2010.07.044  0.797
2010 Han YC, Park CY, Bhagat G, Zhang J, Wang Y, Fan JB, Liu M, Zou Y, Weissman IL, Gu H. MicroRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia Journal of Experimental Medicine. 207: 475-489. PMID 20212066 DOI: 10.1084/Jem.20090831  0.612
2010 Czechowicz A, Bhardwaj R, Park CY, Weissman IL. Targeted Clearance of Human Hematopoietic Stem Cell Niches Via Inhibition of SCF Signaling Using Monoclonal Antibody SR-1 Blood. 116: 74-74. DOI: 10.1182/BLOOD.V116.21.74.74  0.629
2010 Park CY, McGowan KA, Glader B, Barsh GS, Weissman IL. Haploinsufficiency of Ribosomal Protein S6 In Mice Mimics Bone Marrow Failure Syndromes In Humans Blood. 116: 194-194. DOI: 10.1182/Blood.V116.21.194.194  0.587
2010 Chao MP, Alizadeh AA, Tang CZ, Myklebust JH, Varghese B, Jan M, Cha AC, Tan BT, Park CY, Levy R, Weissman IL, Majeti R. Abstract 2440: CD47 is a prognostic factor and an antibody target that synergizes with rituximab to eradicate non-Hodgkin lymphoma Cancer Research. 70: 2440-2440. DOI: 10.1158/1538-7445.Am10-2440  0.721
2009 Jaiswal S, Jamieson CH, Pang WW, Park CY, Chao MP, Majeti R, Traver D, van Rooijen N, Weissman IL. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell. 138: 271-85. PMID 19632178 DOI: 10.1016/J.Cell.2009.05.046  0.819
2009 Park CY, Tseng D, Weissman IL. Cancer stem cell-directed therapies: Recent data from the laboratory and clinic Molecular Therapy. 17: 219-230. PMID 19066601 DOI: 10.1038/Mt.2008.254  0.794
2009 Raval A, Park CY, Pang WW, Kusler B, Sridhar KJ, Gotlib JR, Greenberg PL, Weissman IL, Mitchell BS. NPM1 Haploinsufficiency Results in Increased Numbers of Hematopoietic Stem Cells and Progenitor Cells. Blood. 114: 738-738. DOI: 10.1182/Blood.V114.22.738.738  0.803
2009 Park CY, Pang WW, Greenberg PL, Weissman IL. Myelodysplastic Syndromes Are Characterized by Gene Expression Changes in Hematopoietic Stem Cells and Alterations in Hematopoietic Stem Cell and Myeloid Progenitor Composition. Blood. 114: 1762-1762. DOI: 10.1182/Blood.V114.22.1762.1762  0.811
2008 Park CY, Majeti R, Weissman IL. In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood. Nature Protocols. 3: 1932-40. PMID 19180077 DOI: 10.1038/Nprot.2008.194  0.736
2008 Dulai MS, Park CY, Howell WD, Smyth LT, Desai M, Carter DM, Vogel H. CNS T-cell lymphoma: an under-recognized entity? Acta Neuropathologica. 115: 345-56. PMID 18196250 DOI: 10.1007/S00401-007-0338-Y  0.31
2008 Chao MP, Weissman IL, Park CY. Cancer stem cells: On the verge of clinical translation Laboratory Medicine. 39: 679-686. DOI: 10.1309/Lmtddrgly374Wscq  0.609
2008 Park CY, Han Y, Bhagat G, Fan J, Weissman IL, Gu H. MicroRNA-29a Is An Oncogene in Acute Myeloid Leukemia Blood. 112: 683-683. DOI: 10.1182/Blood.V112.11.683.683  0.622
2007 Majeti R, Park CY, Weissman IL. Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood. Cell Stem Cell. 1: 635-45. PMID 18371405 DOI: 10.1016/j.stem.2007.10.001  0.732
2007 Zhao W, Cha EN, Lee C, Park CY, Schindler C. Stat2-dependent regulation of MHC class II expression. Journal of Immunology (Baltimore, Md. : 1950). 179: 463-71. PMID 17579067 DOI: 10.4049/Jimmunol.179.1.463  0.69
2007 Hosen N, Park CY, Tatsumi N, Oji Y, Sugiyama H, Gramatzki M, Krensky AM, Weissman IL. CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia Proceedings of the National Academy of Sciences of the United States of America. 104: 11008-11013. PMID 17576927 DOI: 10.1073/Pnas.0704271104  0.764
2007 Park CY, Wang Y, Prohaska S, Tseng D, Weissman IL. MicroRNA Profiling of Human Acute Myeloid Leukemia and Normal Hematopoietic Stem/Progenitor Cells Reveals a Leukemia Stem Cell Signature. Blood. 110: 779-779. DOI: 10.1182/Blood.V110.11.779.779  0.791
2006 Tan BT, Park CY, Ailles LE, Weissman IL. The cancer stem cell hypothesis: a work in progress. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 1203-7. PMID 17075578 DOI: 10.1038/Labinvest.3700488  0.628
2006 Park CY, Majeti R, Tan BT, Weissman IL. Development of a Novel Xenotransplantation System for Studying Human Acute Myeloid Leukemia. Blood. 108: 1947-1947. DOI: 10.1182/Blood.V108.11.1947.1947  0.76
2004 Park CY, Bohen SP, Levy R, Warnke RA, Natkunam Y. The Number of CD25+ Tumor-Infiltrating Cells May Predict Clinical Response to Rituximab in Follicular Lymphoma Patients. Blood. 104: 748-748. DOI: 10.1182/Blood.V104.11.748.748  0.414
2000 Park C, Li S, Cha E, Schindler C. Immune response in Stat2 knockout mice Immunity. 13: 795-804. PMID 11163195 DOI: 10.1016/S1074-7613(00)00077-7  0.69
1999 Park C, Lecomte M, Schindler C. Murine Stat2 is uncharacteristically divergent Nucleic Acids Research. 27: 4191-4199. PMID 10518610 DOI: 10.1093/Nar/27.21.4191  0.465
1998 Park C, Schindler C. Protein-DNA interactions in interferon-gamma signaling. Methods. 15: 175-188. PMID 9735303 DOI: 10.1006/Meth.1998.0622  0.442
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