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Ke Ding, Ph.D - Publications

Affiliations: 
1991-1998 China Pharmaceutical University 
 1998-2001 Fudan university, Shanghai, Shanghai Shi, China 
 2006-2016 Guangzhou Institutes Biomedicine and Health,CAS 
 2016- Jinan University 
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Liu W, Bai Y, Zhou L, Jin J, Zhang M, Wang Y, Lin R, Huang W, Ren X, Ma N, Zhou F, Wang Z, Ding K. Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia. European Journal of Medicinal Chemistry. 264: 115974. PMID 38007910 DOI: 10.1016/j.ejmech.2023.115974  0.524
2023 Zhang H, Lin G, Jia S, Zhang Y, Wu J, Tao Y, Huang W, Song M, Ding K, Ma D, Fan M. Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7. European Journal of Medicinal Chemistry. 263: 115955. PMID 38000213 DOI: 10.1016/j.ejmech.2023.115955  0.498
2023 Li C, Qiao Y, Jiang X, Liu L, Zheng Y, Qiu Y, Cheng C, Zhou F, Zhou Y, Huang W, Ren X, Wang Y, Wang Z, Chinnaiyan AM, Ding K. Discovery of a First-in-Class Degrader for the Lipid Kinase PIKfyve. Journal of Medicinal Chemistry. PMID 37605297 DOI: 10.1021/acs.jmedchem.3c00912  0.501
2023 Wei Y, Xu X, Jiang M, Wang Y, Zhou Y, Wang Z, Zhang Z, Zhou F, Ding K. Discovery of new Lenalidomide derivatives as potent and selective GSPT1 degraders. European Journal of Medicinal Chemistry. 258: 115580. PMID 37418973 DOI: 10.1016/j.ejmech.2023.115580  0.514
2023 He R, Song Z, Bai Y, He S, Huang J, Wang Y, Zhou F, Huang W, Guo J, Wang Z, Tu ZC, Ren X, Zhang Z, Xu J, Ding K. Discovery of AXL Degraders with Improved Potencies in Triple-Negative Breast Cancer (TNBC) Cells. Journal of Medicinal Chemistry. PMID 36695404 DOI: 10.1021/acs.jmedchem.2c01682  0.537
2022 Chan S, Zhang Y, Wang J, Yu Q, Peng X, Zou J, Zhou L, Tan L, Duan Y, Zhou Y, Hur H, Ai J, Wang Z, Ren X, Zhang Z, ... Ding K, et al. Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors. Journal of Medicinal Chemistry. PMID 36358010 DOI: 10.1021/acs.jmedchem.2c01346  0.438
2022 Zhang Y, Chan S, He R, Liu Y, Song X, Tu ZC, Ren X, Zhou Y, Zhang Z, Wang Z, Zhou F, Ding K. 1-Methyl-3-((4-(quinolin-4-yloxy)phenyl)amino)-1H-pyrazole-4-carboxamide derivatives as new rearranged during Transfection (RET) kinase inhibitors capable of suppressing resistant mutants in solvent-front regions. European Journal of Medicinal Chemistry. 244: 114862. PMID 36308779 DOI: 10.1016/j.ejmech.2022.114862  0.541
2022 Li S, Zhang P, Xu F, Hu S, Liu J, Tan Y, Tu Z, Sun H, Zhang ZM, He QY, Sun P, Ding K, Li Z. Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. Journal of Medicinal Chemistry. PMID 35880853 DOI: 10.1021/acs.jmedchem.2c00272  0.305
2022 Lu J, Huang Y, Huang J, He R, Huang M, Lu X, Xu Y, Zhou F, Zhang Z, Ding K. Discovery of the First Examples of Threonine Tyrosine Kinase PROTAC Degraders. Journal of Medicinal Chemistry. PMID 35084180 DOI: 10.1021/acs.jmedchem.1c01768  0.528
2020 Zhang YH, Li YF, Wang Y, Tan L, Cao ZQ, Xie C, Xie G, Gong HB, Sun WY, Ouyang SH, Duan WJ, Lu X, Ding K, Kurihara H, Hu D, et al. Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea. Nature Communications. 11: 1473. PMID 32193380 DOI: 10.1038/s41467-020-15324-7  0.346
2019 Tan L, Zhang Z, Gao D, Chan S, Luo J, Tu ZC, Zhang ZM, Ding K, Ren X, Lu X. Quinolone antibiotic derivatives as new selective Axl kinase inhibitors. European Journal of Medicinal Chemistry. 166: 318-327. PMID 30731400 DOI: 10.1016/j.ejmech.2019.01.065  0.427
2016 Lu QP, Chen WD, Peng JR, Xu YD, Cai Q, Feng GK, Ding K, Zhu XF, Guan Z. Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells. Oncology Letters. 12: 3598-3608. PMID 27900042 DOI: 10.3892/ol.2016.5088  0.442
2016 Tan L, Zhang Z, Gao D, Luo J, Tu ZC, Li Z, Peng L, Ren X, Ding K. 4-Oxo-1, 4-Dihydroquinoline-3-Carboxamide Derivatives as New Axl Kinase Inhibitors. Journal of Medicinal Chemistry. PMID 27379978 DOI: 10.1021/Acs.Jmedchem.6B00608  0.427
2016 Li X, Shen J, Tan L, Zhang Z, Gao D, Luo J, Cheng H, Zhou X, Ma J, Ding K, Lu X. Design and synthesis of N-(4-aminopyridin-2-yl)amides as B-Raf(V600E) inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27155899 DOI: 10.1016/j.bmcl.2016.04.076  0.403
2014 Wang W, Kong D, Cheng H, Tan L, Zhang Z, Zhuang X, Long H, Zhou Y, Xu Y, Yang X, Ding K. New benzimidazole-2-urea derivates as tubulin inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 4250-3. PMID 25091926 DOI: 10.1016/j.bmcl.2014.07.035  0.397
2013 Xu T, Zhang L, Xu S, Yang CY, Luo J, Ding F, Lu X, Liu Y, Tu Z, Li S, Pei D, Cai Q, Li H, Ren X, Wang S, ... Ding K, et al. Pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives as selective inhibitors of EGFR threonine790 to methionine790 (T790M) mutants. Angewandte Chemie (International Ed. in English). 52: 8387-90. PMID 23804305 DOI: 10.1002/Anie.201302313  0.406
2012 Zhou F, Guo J, Liu J, Ding K, Yu S, Cai Q. Copper-catalyzed desymmetric intramolecular Ullmann C-N coupling: an enantioselective preparation of indolines. Journal of the American Chemical Society. 134: 14326-9. PMID 22913611 DOI: 10.1021/Ja306631Z  0.693
2012 Cai Q, Yan J, Ding K. A CuAAC/Ullmann C-C coupling tandem reaction: copper-catalyzed reactions of organic azides with N-(2-iodoaryl)propiolamides or 2-iodo-N-(prop-2-ynyl)benzenamines. Organic Letters. 14: 3332-5. PMID 22724380 DOI: 10.1021/Ol301307X  0.457
2012 Yan J, Zhou F, Qin D, Cai T, Ding K, Cai Q. Synthesis of [1,2,3]triazolo[1,5-a]quinoxalin-4(5H)-ones through copper-catalyzed tandem reactions of N-(2-haloaryl)propiolamides with sodium azide. Organic Letters. 14: 1262-5. PMID 22335274 DOI: 10.1021/Ol300114W  0.621
2011 Zhou F, Ding K, Cai Q. Palladium-catalyzed amidation of N-tosylhydrazones with isocyanides. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 12268-71. PMID 21938752 DOI: 10.1002/Chem.201102459  0.586
2011 Zhou F, Liu J, Ding K, Liu J, Cai Q. Copper-catalyzed tandem reaction of isocyanides with N-(2-haloaryl)propiolamides for the synthesis of pyrrolo[3,2-c]quinolin-4-ones. The Journal of Organic Chemistry. 76: 5346-53. PMID 21591728 DOI: 10.1021/Jo2006939  0.618
2011 Wang D, Zhang Z, Lu X, Feng Y, Luo K, Gan J, Yingxue L, Wan J, Li X, Zhang F, Tu Z, Cai Q, Ren X, Ding K. Hybrid compounds as new Bcr/Abl inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 1965-8. PMID 21376587 DOI: 10.1016/J.Bmcl.2011.02.029  0.489
2011 Cai Q, Zhou F, Xu T, Fu L, Ding K. Copper-catalyzed tandem reactions of 1-(2-iodoary)-2-yn-1-ones with isocyanides for the synthesis of 4-oxo-indeno[1,2-b]pyrroles. Organic Letters. 13: 340-343. PMID 21162591 DOI: 10.1021/Ol102826F  0.605
2010 Cai Q, Li Z, Wei J, Fu L, Ha C, Pei D, Ding K. Synthesis of aza-fused polycyclic quinolines through copper-catalyzed cascade reactions. Organic Letters. 12: 1500-3. PMID 20196570 DOI: 10.1021/Ol1002225  0.503
2010 Ding K, Zhang X, Ma D, Wang B. Synthesis and biological activity of l-aminoindan-l,3-dicarboxylic acid, a benzo-analogue of (1S, 3R)-ACPD Chinese Journal of Chemistry. 19: 1232-1238. DOI: 10.1002/Cjoc.20010191212  0.49
2009 Cai Q, Li Z, Wei J, Ha C, Pei D, Ding K. Assembly of indole-2-carboxylic acid esters through a ligand-free copper-catalysed cascade process. Chemical Communications (Cambridge, England). 7581-3. PMID 20024286 DOI: 10.1039/B918345K  0.469
2009 Zhou J, Duan L, Chen H, Ren X, Zhang Z, Zhou F, Liu J, Pei D, Ding K. Atovaquone derivatives as potent cytotoxic and apoptosis inducing agents. Bioorganic & Medicinal Chemistry Letters. 19: 5091-4. PMID 19632833 DOI: 10.1016/J.Bmcl.2009.07.044  0.488
2006 Ma D, Jiang Y, Chen F, Gong LK, Ding K, Xu Y, Wang R, Ge A, Ren J, Li J, Li J, Ye Q. Selective inhibition of matrix metalloproteinase isozymes and in vivo protection against emphysema by substituted gamma-keto carboxylic acids. Journal of Medicinal Chemistry. 49: 456-8. PMID 16420030 DOI: 10.1021/Jm051101G  0.595
2002 Ma D, Ding K, Tian H, Wang B, Cheng D. Asymmetric synthesis of (S)-1-aminoindan-1,5-dicarboxylic acid and related analogues via intramolecular acylation of enantiopure α,α-disubstituted amino acids Tetrahedron: Asymmetry. 13: 961-969. DOI: 10.1016/S0957-4166(02)00224-0  0.669
2001 Ding K, Ma D. Asymmetric synthesis of α,α-disubstituted amino acids by diastereoselective functionalization of enantiopure phenyloxazinones, derivatives of asymmetric Strecker reaction products of aldehydes Tetrahedron. 57: 6361-6366. DOI: 10.1016/S0040-4020(01)00502-6  0.519
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