Year |
Citation |
Score |
2020 |
Montalbán-López M, Scott TA, Ramesh S, Rahman IR, van Heel AJ, Viel JH, Bandarian V, Dittmann E, Genilloud O, Goto Y, Grande Burgos MJ, Hill C, Kim S, Koehnke J, Latham JA, ... ... Piel J, et al. New developments in RiPP discovery, enzymology and engineering. Natural Product Reports. PMID 32935693 DOI: 10.1039/D0Np00027B |
0.303 |
|
2020 |
Mordhorst S, Morinaka BI, Vagstad AL, Piel J. Posttranslationally Acting Arginases Provide a Ribosomal Route to Non-proteinogenic Ornithine Residues in Diverse Peptide Sequences. Angewandte Chemie (International Ed. in English). PMID 32780902 DOI: 10.1002/Anie.202008990 |
0.722 |
|
2020 |
Rust M, Helfrich EJN, Freeman MF, Nanudorn P, Field CM, Rückert C, Kündig T, Page MJ, Webb VL, Kalinowski J, Sunagawa S, Piel J. A multiproducer microbiome generates chemical diversity in the marine sponge . Proceedings of the National Academy of Sciences of the United States of America. PMID 32291345 DOI: 10.1073/Pnas.1919245117 |
0.626 |
|
2020 |
Bösch NM, Borsa M, Greczmiel U, Morinaka BI, Gugger M, Oxenius A, Vagstad AL, Piel J. Landornamides: Antiviral Ornithine-Containing Ribosomal Peptides Discovered through Genome Mining. Angewandte Chemie (International Ed. in English). PMID 32163654 DOI: 10.1002/Anie.201916321 |
0.748 |
|
2019 |
Scott TA, Piel J. The hidden enzymology of bacterial natural product biosynthesis. Nature Reviews. Chemistry. 3: 404-425. PMID 32232178 DOI: 10.1038/s41570-019-0107-1 |
0.356 |
|
2019 |
Bhushan A, Egli PJ, Peters EE, Freeman MF, Piel J. Genome mining- and synthetic biology-enabled production of hypermodified peptides. Nature Chemistry. PMID 31501509 DOI: 10.1038/S41557-019-0323-9 |
0.678 |
|
2019 |
Reiter S, Cahn JKB, Wiebach V, Ueoka R, Piel J. Characterization of an Orphan Type III Polyketide Synthase Conserved in Uncultivated "Entotheonella" Sponge Symbionts. Chembiochem : a European Journal of Chemical Biology. 21: 564-571. PMID 31430416 DOI: 10.1002/cbic.201900352 |
0.305 |
|
2019 |
Helfrich EJN, Ueoka R, Dolev A, Rust M, Meoded RA, Bhushan A, Califano G, Costa R, Gugger M, Steinbeck C, Moreno P, Piel J. Automated structure prediction of trans-acyltransferase polyketide synthase products. Nature Chemical Biology. PMID 31308532 DOI: 10.1038/S41589-019-0313-7 |
0.627 |
|
2019 |
Stöckli M, Morinaka BI, Lackner G, Kombrink A, Sieber R, Margot C, Stanley CE, deMello AJ, Piel J, Künzler M. Bacteria-induced production of the antibacterial sesquiterpene lagopodin B in Coprinopsis cinerea. Molecular Microbiology. PMID 31087720 DOI: 10.1111/Mmi.14277 |
0.676 |
|
2019 |
Helf MJ, Freeman MF, Piel J. Investigations into PoyH, a promiscuous protease from polytheonamide biosynthesis. Journal of Industrial Microbiology & Biotechnology. PMID 30627933 DOI: 10.1007/S10295-018-02129-3 |
0.82 |
|
2018 |
Vagstad AL, Kuranaga T, Püntener S, Pattabiraman VR, Bode JW, Piel J. Introduction of D-Amino Acids in Minimalistic Peptide Substrates by an S-Adenosyl-L-Methionine Radical Epimerase. Angewandte Chemie (International Ed. in English). PMID 30521081 DOI: 10.1002/Anie.201809508 |
0.37 |
|
2018 |
Moosmann P, Ueoka R, Gugger M, Piel J. Aranazoles: Extensively Chlorinated Nonribosomal Peptide-Polyketide Hybrids from the Cyanobacterium Fischerella sp. PCC 9339. Organic Letters. 20: 5238-5241. PMID 30141631 DOI: 10.1021/acs.orglett.8b02193 |
0.389 |
|
2018 |
Helfrich EJN, Vogel CM, Ueoka R, Schäfer M, Ryffel F, Müller DB, Probst S, Kreuzer M, Piel J, Vorholt JA. Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome. Nature Microbiology. 3: 909-919. PMID 30038309 DOI: 10.1038/S41564-018-0200-0 |
0.304 |
|
2018 |
Ueoka R, Bhushan A, Probst SI, Bray WM, Lokey RS, Linington RG, Piel J. Genome-based identification of a plant-associated marine bacterium as a rich natural product source. Angewandte Chemie (International Ed. in English). PMID 30025185 DOI: 10.1002/Anie.201805673 |
0.349 |
|
2018 |
Uria AR, Piel J, Wakimoto T. Biosynthetic Insights of Calyculin- and Misakinolide-Type Compounds in "Candidatus Entotheonella sp." Methods in Enzymology. 604: 287-330. PMID 29779656 DOI: 10.1016/bs.mie.2018.02.017 |
0.34 |
|
2018 |
Morinaka BI, Vagstad AL, Piel J. Radical S-Adenosylmethionine Peptide Epimerases: Detection of Activity and Characterization of d-Amino Acid Products. Methods in Enzymology. 604: 237-257. PMID 29779654 DOI: 10.1016/Bs.Mie.2018.01.033 |
0.721 |
|
2018 |
Morinaka BI, Lakis E, Verest M, Helf MJ, Scalvenzi T, Vagstad AL, Sims J, Sunagawa S, Gugger M, Piel J. Natural noncanonical protein splicing yields products with diverse β-amino acid residues. Science (New York, N.Y.). 359: 779-782. PMID 29449488 DOI: 10.1126/Science.Aao0157 |
0.78 |
|
2018 |
Mori T, Cahn JKB, Wilson MC, Meoded RA, Wiebach V, Martinez AFC, Helfrich EJN, Albersmeier A, Wibberg D, Dätwyler S, Keren R, Lavy A, Rückert C, Ilan M, Kalinowski J, ... ... Piel J, et al. Single-bacterial genomics validates rich and varied specialized metabolism of uncultivatedsponge symbionts. Proceedings of the National Academy of Sciences of the United States of America. PMID 29439203 DOI: 10.1073/Pnas.1715496115 |
0.742 |
|
2018 |
Puri AW, Mevers E, Ramadhar TR, Petras D, Liu D, Piel J, Dorrestein PC, Greenberg P, Lidstrom ME, Clardy J. Tundrenone: An Atypical Secondary Metabolite from Bacteria with Highly Restricted Primary Metabolism. Journal of the American Chemical Society. PMID 29361220 DOI: 10.1021/Jacs.7B12240 |
0.423 |
|
2018 |
Crüsemann M, Reher R, Schamari I, Brachmann AO, Ohbayashi T, Kuschak M, Malfacini D, Seidinger A, Pinto-Carbó M, Richarz R, Reuter T, Kehraus S, Hallab A, Attwood M, Schiöth HB, ... ... Piel J, et al. Heterologous Expression, Biosynthetic Studies, and Ecological Function of the Selective Gq-Signaling Inhibitor FR900359. Angewandte Chemie (International Ed. in English). 57: 836-840. PMID 29194875 DOI: 10.1002/Anie.201707996 |
0.331 |
|
2017 |
Ueoka R, Bortfeld-Miller M, Morinaka BI, Vorholt JA, Piel J. Toblerols: Cyclopropanol-Containing Polyketide Modulators of Antibiosis in Methylobacteria. Angewandte Chemie (International Ed. in English). PMID 29112783 DOI: 10.1002/Anie.201709056 |
0.695 |
|
2017 |
van der Velden NS, Kälin N, Helf MJ, Piel J, Freeman MF, Künzler M. Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products. Nature Chemical Biology. 13: 833-835. PMID 28581484 DOI: 10.1038/Nchembio.2393 |
0.795 |
|
2017 |
Moosmann P, Ueoka R, Grauso L, Mangoni A, Morinaka BI, Gugger M, Piel J. Cyanobacterial ent-Sterol-Like Natural Products from a Deviated Ubiquinone Pathway. Angewandte Chemie (International Ed. in English). PMID 28370791 DOI: 10.1002/Anie.201611617 |
0.714 |
|
2017 |
Freeman MF, Helf MJ, Bhushan A, Morinaka BI, Piel J. Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium. Nature Chemistry. 9: 387-395. PMID 28338684 DOI: 10.1038/Nchem.2666 |
0.8 |
|
2017 |
Smith DR, Uria AR, Helfrich EJ, Milbredt D, van-Pee KH, Piel J, Goss RJ. An unusual flavin-dependent halogenase from the metagenome of the marine sponge Theonella swinhoei WA. Acs Chemical Biology. PMID 28198609 DOI: 10.1021/acschembio.6b01115 |
0.366 |
|
2017 |
Pancrace C, Barny MA, Ueoka R, Calteau A, Scalvenzi T, Pédron J, Barbe V, Piel J, Humbert JF, Gugger M. Insights into the Planktothrix genus: Genomic and metabolic comparison of benthic and planktic strains. Scientific Reports. 7: 41181. PMID 28117406 DOI: 10.1038/Srep41181 |
0.334 |
|
2017 |
Helf MJ, Jud A, Piel J. Enzyme from an Uncultivated Sponge Bacterium Catalyzes S-Methylation in a Ribosomal Peptide. Chembiochem : a European Journal of Chemical Biology. 18: 444-450. PMID 27966282 DOI: 10.1002/Cbic.201600594 |
0.806 |
|
2016 |
Aranda M, Li Y, Liew YJ, Baumgarten S, Simakov O, Wilson MC, Piel J, Ashoor H, Bougouffa S, Bajic VB, Ryu T, Ravasi T, Bayer T, Micklem G, Kim H, et al. Genomes of coral dinoflagellate symbionts highlight evolutionary adaptations conducive to a symbiotic lifestyle. Scientific Reports. 6: 39734. PMID 28004835 DOI: 10.1038/Srep39734 |
0.639 |
|
2016 |
Morinaka BI, Verest M, Freeman MF, Gugger M, Piel J. An Orthogonal D2 O-Based Induction System that Provides Insights into d-Amino Acid Pattern Formation by Radical S-Adenosylmethionine Peptide Epimerases. Angewandte Chemie (International Ed. in English). PMID 27958669 DOI: 10.1002/Anie.201609469 |
0.778 |
|
2016 |
Fuchs SW, Lackner G, Morinaka BI, Morishita Y, Asai T, Riniker S, Piel J. A Lanthipeptide-like N-Terminal Leader Region Guides Peptide Epimerization by Radical SAM Epimerases: Implications for RiPP Evolution. Angewandte Chemie (International Ed. in English). PMID 27584723 DOI: 10.1002/Anie.201602863 |
0.706 |
|
2016 |
Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, ... ... Piel J, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/Nbt.3597 |
0.734 |
|
2015 |
Freeman MF, Vagstad AL, Piel J. Polytheonamide biosynthesis showcasing the metabolic potential of sponge-associated uncultivated 'Entotheonella' bacteria. Current Opinion in Chemical Biology. 31: 8-14. PMID 26625171 DOI: 10.1016/J.Cbpa.2015.11.002 |
0.643 |
|
2015 |
Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, ... ... Piel J, et al. Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology. 11: 625-31. PMID 26284661 DOI: 10.1038/Nchembio.1890 |
0.759 |
|
2015 |
Ueoka R, Uria AR, Reiter S, Mori T, Karbaum P, Peters EE, Helfrich EJ, Morinaka BI, Gugger M, Takeyama H, Matsunaga S, Piel J. Metabolic and evolutionary origin of actin-binding polyketides from diverse organisms. Nature Chemical Biology. 11: 705-12. PMID 26236936 DOI: 10.1038/Nchembio.1870 |
0.694 |
|
2014 |
Fahad AA, Abood A, Fisch KM, Osipow A, Davison J, Avramovi? M, Butts CP, Piel J, Simpson TJ, Cox RJ. Oxidative dearomatisation: the key step of sorbicillinoid biosynthesis†Electronic supplementary information (ESI) available: Containing all experimental details. See DOI: 10.1039/c3sc52911hClick here for additional data file. Chemical Science (Royal Society of Chemistry : 2010). 5: 523-527. PMID 25580210 DOI: 10.1039/C3Sc52911H |
0.387 |
|
2014 |
Calteau A, Fewer DP, Latifi A, Coursin T, Laurent T, Jokela J, Kerfeld CA, Sivonen K, Piel J, Gugger M. Phylum-wide comparative genomics unravel the diversity of secondary metabolism in Cyanobacteria. Bmc Genomics. 15: 977. PMID 25404466 DOI: 10.1186/1471-2164-15-977 |
0.368 |
|
2014 |
Morinaka BI, Vagstad AL, Helf MJ, Gugger M, Kegler C, Freeman MF, Bode HB, Piel J. Radical S-adenosyl methionine epimerases: regioselective introduction of diverse D-amino acid patterns into peptide natural products. Angewandte Chemie (International Ed. in English). 53: 8503-7. PMID 24943072 DOI: 10.1002/Anie.201400478 |
0.802 |
|
2014 |
Gay DC, Gay G, Axelrod AJ, Jenner M, Kohlhaas C, Kampa A, Oldham NJ, Piel J, Keatinge-Clay AT. A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase. Structure (London, England : 1993). 22: 444-51. PMID 24508341 DOI: 10.1016/J.Str.2013.12.016 |
0.382 |
|
2014 |
Wilson MC, Mori T, Rückert C, Uria AR, Helf MJ, Takada K, Gernert C, Steffens UA, Heycke N, Schmitt S, Rinke C, Helfrich EJ, Brachmann AO, Gurgui C, Wakimoto T, ... ... Piel J, et al. An environmental bacterial taxon with a large and distinct metabolic repertoire. Nature. 506: 58-62. PMID 24476823 DOI: 10.1038/Nature12959 |
0.815 |
|
2014 |
Wilson MC, Mori T, Rückert C, Uria AR, Helf MJ, Takada K, Gernert C, Steffens UAE, Heycke N, Schmitt S, Rinke C, Helfrich EJN, Brachmann AO, Gurgui C, Wakimoto T, ... ... Piel J, et al. Erratum: Corrigendum: An environmental bacterial taxon with a large and distinct metabolic repertoire Nature. 507: 262-262. DOI: 10.1038/Nature13126 |
0.765 |
|
2013 |
Pöplau P, Frank S, Morinaka BI, Piel J. An enzymatic domain for the formation of cyclic ethers in complex polyketides Angewandte Chemie - International Edition. 52: 13215-13218. PMID 24307486 DOI: 10.1002/Anie.201307406 |
0.618 |
|
2013 |
Kampa A, Gagunashvili AN, Gulder TAM, Morinaka BI, Daolio C, Godejohann M, Miao VPW, Piel J, Andrésson OS. Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways in diverse symbioses Proceedings of the National Academy of Sciences of the United States of America. 110: E3129-E3137. PMID 23898213 DOI: 10.1073/Pnas.1305867110 |
0.726 |
|
2013 |
Cai X, Teta R, Kohlhaas C, Crüsemann M, Ueoka R, Mangoni A, Freeman MF, Piel J. Manipulation of regulatory genes reveals complexity and fidelity in hormaomycin biosynthesis. Chemistry & Biology. 20: 839-46. PMID 23790494 DOI: 10.1016/J.Chembiol.2013.04.018 |
0.655 |
|
2013 |
Wilson MC, Piel J. Metagenomic approaches for exploiting uncultivated bacteria as a resource for novel biosynthetic enzymology. Chemistry & Biology. 20: 636-47. PMID 23706630 DOI: 10.1016/J.Chembiol.2013.04.011 |
0.685 |
|
2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Piel J, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/C2Np20085F |
0.789 |
|
2013 |
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Piel J, et al. Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) Natural Product Reports. 30: 1568-1568. DOI: 10.1039/C3Np90040A |
0.787 |
|
2013 |
Pöplau P, Frank S, Morinaka BI, Piel J. Eine enzymatische Domäne für die Erzeugung cyclischer Ether in komplexen Polyketiden Angewandte Chemie. 125: 13457-13460. DOI: 10.1002/Ange.201307406 |
0.598 |
|
2012 |
Freeman MF, Gurgui C, Helf MJ, Morinaka BI, Uria AR, Oldham NJ, Sahl HG, Matsunaga S, Piel J. Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides. Science (New York, N.Y.). 338: 387-90. PMID 22983711 DOI: 10.1126/Science.1226121 |
0.81 |
|
2012 |
Jensen K, Niederkrüger H, Zimmermann K, Vagstad AL, Moldenhauer J, Brendel N, Frank S, Pöplau P, Kohlhaas C, Townsend CA, Oldiges M, Hertweck C, Piel J. Polyketide proofreading by an acyltransferase-like enzyme. Chemistry & Biology. 19: 329-39. PMID 22444588 DOI: 10.1016/J.Chembiol.2012.01.005 |
0.62 |
|
2012 |
Freeman MF, Gurgui C, Helf MJ, Morinaka BI, Uria AR, Oldham NJ, Sahl HG, Matsunaga S, Piel J. Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides Science. 338: 387-390. DOI: 10.1126/science.1226521 |
0.757 |
|
2012 |
Piel J, Freeman M, Gurgui C, Helf M, Morinaka B, Wilson M, Mori T, Rueckert C, Steffens U, Takada K, Gernert C, Uria A, Wakimoto T, Abe I, Hentschel U, et al. Chemical surprises from an uncultivated sponge symbiont Planta Medica. 78. DOI: 10.1055/S-0032-1320225 |
0.797 |
|
2011 |
Donia MS, Fricke WF, Partensky F, Cox J, Elshahawi SI, White JR, Phillippy AM, Schatz MC, Piel J, Haygood MG, Ravel J, Schmidt EW. Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis. Proceedings of the National Academy of Sciences of the United States of America. 108: E1423-32. PMID 22123943 DOI: 10.1073/Pnas.1111712108 |
0.393 |
|
2011 |
Herzner AM, Dischinger J, Szekat C, Josten M, Schmitz S, Yakéléba A, Reinartz R, Jansen A, Sahl HG, Piel J, Bierbaum G. Expression of the lantibiotic mersacidin in Bacillus amyloliquefaciens FZB42 Plos One. 6. PMID 21811596 DOI: 10.1371/journal.pone.0022389 |
0.359 |
|
2011 |
Piel J. Approaches to capturing and designing biologically active small molecules produced by uncultured microbes Annual Review of Microbiology. 65: 431-453. PMID 21682647 DOI: 10.1146/annurev-micro-090110-102805 |
0.334 |
|
2011 |
Höfer I, Crüsemann M, Radzom M, Geers B, Flachshaar D, Cai X, Zeeck A, Piel J. Insights into the biosynthesis of hormaomycin, an exceptionally complex bacterial signaling metabolite Chemistry and Biology. 18: 381-391. PMID 21439483 DOI: 10.1016/J.Chembiol.2010.12.018 |
0.428 |
|
2011 |
Gulder TA, Freeman MF, Piel J. The Catalytic Diversity of Multimodular Polyketide Synthases: Natural Product Biosynthesis Beyond Textbook Assembly Rules. Topics in Current Chemistry. PMID 21360321 DOI: 10.1007/128_2010_113 |
0.778 |
|
2011 |
Jaspars M, Moore B, Piel J, Cox R. Editorial: Marine Natural Products themed issue Natural Product Reports. 28: 181. PMID 21229158 DOI: 10.1039/c0np90037k |
0.611 |
|
2010 |
Hochmuth T, Niederkrüger H, Gernert C, Siegl A, Taudien S, Platzer M, Crews P, Hentschel U, Piel J. Linking chemical and microbial diversity in marine sponges: Possible role for poribacteria as producers of methyl-branched fatty acids Chembiochem. 11: 2572-2578. PMID 21077090 DOI: 10.1002/Cbic.201000510 |
0.313 |
|
2010 |
Gurgui C, Piel J. Metagenomic approaches to identify and isolate bioactive natural products from microbiota of marine sponges. Methods in Molecular Biology (Clifton, N.J.). 668: 247-264. PMID 20830569 |
0.311 |
|
2010 |
Irschik H, Kopp M, Weissman KJ, Buntin K, Piel J, Müller R. Analysis of the sorangicin gene cluster reinforces the utility of a combined phylogenetic/retrobiosynthetic analysis for deciphering natural product assembly by trans-AT PKS Chembiochem. 11: 1840-1849. PMID 20715267 DOI: 10.1002/Cbic.201000313 |
0.418 |
|
2010 |
Erol O, Schäberle TF, Schmitz A, Rachid S, Gurgui C, El Omari M, Lohr F, Kehraus S, Piel J, Müller R, Königd GM. Biosynthesis of the myxobacterial antibiotic corallopyronin A Chembiochem. 11: 1253-1265. PMID 20503218 DOI: 10.1002/Cbic.201000085 |
0.438 |
|
2010 |
PIEL J, BOLAND W. ChemInform Abstract: Highly Efficient and Versatile Synthesis of Isotopically Labelled 1- Deoxy-D-xylulose. Cheminform. 28: no-no. DOI: 10.1002/chin.199749227 |
0.372 |
|
2009 |
Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J. Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting. Nature Chemical Biology. 5: 494-501. PMID 19448639 DOI: 10.1038/Nchembio.176 |
0.319 |
|
2009 |
Hochmuth T, Piel J. Polyketide synthases of bacterial symbionts in sponges - Evolution-based applications in natural products research Phytochemistry. 70: 1841-1849. PMID 19443000 DOI: 10.1016/j.phytochem.2009.04.010 |
0.369 |
|
2009 |
Chen XH, Koumoutsi A, Scholz R, Schneider K, Vater J, Süssmuth R, Piel J, Borriss R. Genome analysis of Bacillus amyloliquefaciens FZB42 reveals its potential for biocontrol of plant pathogens. Journal of Biotechnology. 140: 27-37. PMID 19041913 DOI: 10.1016/J.Jbiotec.2008.10.011 |
0.338 |
|
2008 |
Nguyen T, Ishida K, Jenke-Kodama H, Dittmann E, Gurgui C, Hochmuth T, Taudien S, Platzer M, Hertweck C, Piel J. Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection Nature Biotechnology. 26: 225-233. PMID 18223641 DOI: 10.1038/Nbt1379 |
0.517 |
|
2008 |
Van der Sar S, Fisch K, Gurgui C, Nguyen T, Piel J, Webb V. Targeting secondary metabolite biosynthetic genes from the metagenome of the sponge Mycale sp Planta Medica. 74. DOI: 10.1055/S-0028-1084798 |
0.309 |
|
2007 |
Lackner G, Schenk A, Xu Z, Reinhardt K, Yunt ZS, Piel J, Hertweck C. Biosynthesis of pentangular polyphenols: deductions from the benastatin and griseorhodin pathways. Journal of the American Chemical Society. 129: 9306-12. PMID 17625850 DOI: 10.1021/Ja0718624 |
0.495 |
|
2007 |
Ping L, Büchler R, Mithöfer A, Svatos A, Spiteller D, Dettner K, Gmeiner S, Piel J, Schlott B, Boland W. A novel Dps-type protein from insect gut bacteria catalyses hydrolysis and synthesis of N-acyl amino acids. Environmental Microbiology. 9: 1572-83. PMID 17504494 DOI: 10.1111/J.1462-2920.2007.01279.X |
0.457 |
|
2007 |
Fieseler L, Hentschel U, Grozdanov L, Schirmer A, Wen G, Platzer M, Hrvatin S, Butzke D, Zimmermann K, Piel J. Widespread occurrence and genomic context of unusually small polyketide synthase genes in microbial consortia associated with marine sponges. Applied and Environmental Microbiology. 73: 2144-55. PMID 17293531 DOI: 10.1128/Aem.02260-06 |
0.349 |
|
2006 |
Piel J. Bacterial symbionts: prospects for the sustainable production of invertebrate-derived pharmaceuticals. Current Medicinal Chemistry. 13: 39-50. PMID 16457638 DOI: 10.2174/092986706775197971 |
0.346 |
|
2005 |
Piel J, Butzke D, Fusetani N, Hui D, Platzer M, Wen G, Matsunaga S. Exploring the chemistry of uncultivated bacterial symbionts: antitumor polyketides of the pederin family. Journal of Natural Products. 68: 472-9. PMID 15787465 DOI: 10.1021/np049612d |
0.341 |
|
2004 |
Piel J, Hui D, Wen G, Butzke D, Platzer M, Fusetani N, Matsunaga S. Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei. Proceedings of the National Academy of Sciences of the United States of America. 101: 16222-7. PMID 15520376 DOI: 10.1073/pnas.0405976101 |
0.356 |
|
2004 |
Piel J, Wen G, Platzer M, Hui D. Unprecedented diversity of catalytic domains in the first four modules of the putative pederin polyketide synthase. Chembiochem : a European Journal of Chemical Biology. 5: 93-8. PMID 14695518 DOI: 10.1002/cbic.200300782 |
0.312 |
|
2002 |
Moore BS, Hertweck C, Hopke JN, Izumikawa M, Kalaitzis JA, Nilsen G, O'Hare T, Piel J, Shipley PR, Xiang L, Austin MB, Noel JP. Plant-like biosynthetic pathways in bacteria: from benzoic acid to chalcone. Journal of Natural Products. 65: 1956-62. PMID 12502351 DOI: 10.1021/Np020230M |
0.712 |
|
2002 |
Spiteller D, Jux A, Piel J, Boland W. Feeding of [5,5-2H(2)]-1-desoxy-D-xylulose and [4,4,6,6,6-2H(5)]-mevalolactone to a geosmin-producing Streptomyces sp. and Fossombronia pusilla. Phytochemistry. 61: 827-34. PMID 12453575 DOI: 10.1016/S0031-9422(02)00282-0 |
0.389 |
|
2002 |
Piel J. A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles. Proceedings of the National Academy of Sciences of the United States of America. 99: 14002-7. PMID 12381784 DOI: 10.1073/pnas.222481399 |
0.351 |
|
2000 |
Moore BS, Piel J. Engineering biodiversity with type II polyketide synthase genes. Antonie Van Leeuwenhoek. 78: 391-8. PMID 11386362 DOI: 10.1023/A:1010273224820 |
0.625 |
|
2000 |
Piel J, Hertweck C, Shipley PR, Hunt DM, Newman MS, Moore BS. Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase. Chemistry & Biology. 7: 943-55. PMID 11137817 DOI: 10.1016/S1074-5521(00)00044-2 |
0.723 |
|
2000 |
Piel J, Hoang K, Moore BS. Natural metabolic diversity encoded by the enterocin biosynthesis gene cluster [15] Journal of the American Chemical Society. 122: 5415-5416. DOI: 10.1021/Ja000445N |
0.631 |
|
1999 |
Boland W, Koch T, Krumm T, Piel J, Jux A. Induced biosynthesis of insect semiochemicals in plants. Novartis Foundation Symposium. 223: 110-26; discussion 1. PMID 10549551 DOI: 10.1002/9780470515679.Ch8 |
0.448 |
|
1999 |
Stanjek V, Piel J, Boland W. Biosynthesis of furanocoumarins: Mevalonate-independent prenylation of umbelliferone in Apium graveolens (Apiaceae) Phytochemistry. 50: 1141-1145. DOI: 10.1016/S0031-9422(98)00650-5 |
0.4 |
|
1998 |
Piel J, Donath J, Bandemer K, Boland W. Mevalonate-independent biosynthesis of terpenoid volatiles in plants: Induced and constitutive emission of volatiles Angewandte Chemie - International Edition. 37: 2478-2481. DOI: 10.1002/(SICI)1521-3773(19981002)37:18<2478::AID-ANIE2478>3.0.CO;2-Q |
0.339 |
|
1998 |
Piel J, Donath J, Bandemer K, Boland W. Induzierte und konstitutiv emittierte Pflanzendüfte: Mevalonat-unabhängige Biosynthese terpenoider Duftstoffe Angewandte Chemie. 110: 2622-2625. DOI: 10.1002/(Sici)1521-3757(19980918)110:18<2622::Aid-Ange2622>3.0.Co;2-F |
0.333 |
|
1997 |
Piel J, Atzorn R, Gäbler R, Kühnemann F, Boland W. Cellulysin from the plant parasitic fungus Trichoderma viride elicits volatile biosynthesis in higher plants via the octadecanoid signalling cascade. Febs Letters. 416: 143-8. PMID 9369200 DOI: 10.1016/S0014-5793(97)01169-1 |
0.378 |
|
1997 |
Piel J, Boland W. Highly efficient and versatile synthesis of isotopically labelled 1-deoxy-D-xylulose Tetrahedron Letters. 38: 6387-6390. DOI: 10.1016/S0040-4039(97)01448-2 |
0.396 |
|
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