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Aaron Klug

Affiliations: 
MRC Laboratory of Molecular Biology University of Cambridge, Cambridge, England, United Kingdom 
Area:
Transcription factors, Biochemistry, structural chemistry
Website:
http://nobelprize.org/nobel_prizes/chemistry/laureates/1982/klug.html
Google:
"Aaron Klug"
Bio:

http://www.nasonline.org/member-directory/members/45989.html
The Nobel Prize in Chemistry 1982 was awarded to Aaron Klug "for his development of crystallographic electron microscopy and his structural elucidation of biologically important nucleic acid-protein complexes".

Mean distance: 7.93 (cluster 32)
 
SNBCP
Cross-listing: Chemistry Tree

Children

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Leonid A. Turkevich research assistant 1971-1973 Cambridge
Daniela Rhodes grad student (Chemistry Tree)
Kenneth C. Holmes grad student 1959 Birkbeck (Computational Biology Tree)
Linda A. Amos grad student 1975 Cambridge (Chemistry Tree)
Alfonso Mondragón grad student 1981-1984 MRC-LMB (Chemistry Tree)
Alfonso Mondragón grad student 1981-1984 MRC-LMB (Chemistry Tree)
Gérard Bricogne post-doc MRC-LMB (Chemistry Tree)
Roger D. Kornberg post-doc MRC-LMB (Chemistry Tree)
Wesley I. Sundquist post-doc (Chemistry Tree)
Jonathan A. King post-doc 1970 MRC-LMB (Chemistry Tree)
Michael Levitt post-doc 1971-1972 MRC-LMB (Chemistry Tree)
Jon D. Robertus post-doc 1972-1974 MRC-LMB (Chemistry Tree)
Timothy J. Richmond post-doc 1978-1980 MRC-LMB (Chemistry Tree)
Raúl Padrón post-doc 1980-1980 MRC-LMB (Cell Biology Tree)
Clarence E. Schutt post-doc 1985 MRC-LMB (Chemistry Tree)
William Gregory Scott post-doc 1993-1996 MRC-LMB (Chemistry Tree)
Venkat Gopalan post-doc 1998 MRC-LMB (Chemistry Tree)
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Publications

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Klug A. (2010) The discovery of zinc fingers and their development for practical applications in gene regulation and genome manipulation. Quarterly Reviews of Biophysics. 43: 1-21
Klug A. (2010) The discovery of zinc fingers and their applications in gene regulation and genome manipulation. Annual Review of Biochemistry. 79: 213-31
Klug A. (2010) From virus structure to chromatin: X-ray diffraction to three-dimensional electron microscopy. Annual Review of Biochemistry. 79: 1-35
Minczuk M, Papworth MA, Miller JC, et al. (2008) Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA. Nucleic Acids Research. 36: 3926-38
Santiago Y, Chan E, Liu PQ, et al. (2008) Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases. Proceedings of the National Academy of Sciences of the United States of America. 105: 5809-14
Shieh JC, Cheng YC, Su MC, et al. (2007) Tailor-made zinc-finger transcription factors activate FLO11 gene expression with phenotypic consequences in the yeast Saccharomyces cerevisiae. Plos One. 2: e746
Lu D, Klug A. (2007) Invariance of the zinc finger module: a comparison of the free structure with those in nucleic-acid complexes. Proteins. 67: 508-12
Minczuk M, Papworth MA, Kolasinska P, et al. (2006) Sequence-specific modification of mitochondrial DNA using a chimeric zinc finger methylase. Proceedings of the National Academy of Sciences of the United States of America. 103: 19689-94
Spillantini MG, Murrell JR, Goedert M, et al. (2006) Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD). Journal of Alzheimer's Disease : Jad. 9: 373-80
Goedert M, Klug A, Crowther RA. (2006) Tau protein, the paired helical filament and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 9: 195-207
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