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Shawn H. Pfeil, Ph.D.

Affiliations: 
2009 Physics University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
Experimental Biological Physics
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"Shawn Pfeil"
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Everett A. Lipman grad student 2009 UC Santa Barbara
 (Microfluidic mixing for non-equilibrium single-molecule optical spectroscopy.)

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Publications

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Hofmann H, Hillger F, Delley C, et al. (2014) Role of denatured-state properties in chaperonin action probed by single-molecule spectroscopy. Biophysical Journal. 107: 2891-2902
Lawrence C, Vallée-Bélisle A, Pfeil SH, et al. (2014) A comparison of the folding kinetics of a small, artificially selected DNA aptamer with those of equivalently simple naturally occurring proteins. Protein Science : a Publication of the Protein Society. 23: 56-66
Wunderlich B, Nettels D, Benke S, et al. (2013) Microfluidic mixer designed for performing single-molecule kinetics with confocal detection on timescales from milliseconds to minutes. Nature Protocols. 8: 1459-74
Borgia A, Wensley BG, Soranno A, et al. (2012) Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy. Nature Communications. 3: 1195
Soranno A, Buchli B, Nettels D, et al. (2012) Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 109: 17800-6
Doerr D, Kuenemuth R, Pfeil SH, et al. (2011) Maximizing Photon Counts and Time Resolution for Single Molecule Fluorescence Studies in Micro Fluidic Mixing System Biophysical Journal. 100: 137a
Hofmann H, Hillger F, Pfeil SH, et al. (2010) Single-molecule spectroscopy of protein folding in a chaperonin cage. Proceedings of the National Academy of Sciences of the United States of America. 107: 11793-8
Wickersham CE, Cash KJ, Pfeil SH, et al. (2010) Tracking a molecular motor with a nanoscale optical encoder. Nano Letters. 10: 1022-7
Wickersham CE, Kerr DH, Cash KJ, et al. (2010) Synthesis of Extended Single-Molecule Optical Encoders Biophysical Journal. 98: 623a
Pfeil SH, Wickersham CE, Hoffmann A, et al. (2009) A microfluidic mixing system for single-molecule measurements. The Review of Scientific Instruments. 80: 055105
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