George R. Dubyak

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Zhang Q, Liu W, Wang H, et al. (2022) TH17 cells promote CNS inflammation by sensing danger signals via Mincle. Nature Communications. 13: 2406
Fort BP, Dubyak GR, Greenfield EM. (2020) Lysosomal disruption by orthopaedic wear particles induces activation of the NLRP3 inflammasome and macrophage cell death by distinct mechanisms. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Bulek K, Zhao J, Liao Y, et al. (2020) Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis. The Journal of Clinical Investigation
Karmakar M, Minns M, Greenberg EN, et al. (2020) N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis. Nature Communications. 11: 2212
Dubyak GR. (2019) Luciferase-assisted detection of extracellular ATP and ATP metabolites during immunogenic death of cancer cells. Methods in Enzymology. 629: 81-102
Portillo JC, Van Grol J, Saffo S, et al. (2019) CD40 in endothelial cells restricts neural tissue invasion by . Infection and Immunity
Manzano GW, Fort BP, Dubyak GR, et al. (2018) Wear Particle-induced Priming of the NLRP3 Inflammasome Depends on Adherent Pathogen-associated Molecular Patterns and Their Cognate Toll-like Receptors: An In Vitro Study. Clinical Orthopaedics and Related Research. 476: 2442-2453
Zhang CJ, Jiang M, Zhou H, et al. (2018) TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation. The Journal of Clinical Investigation
Rathkey JK, Zhao J, Liu Z, et al. (2018) Chemical disruption of the pyroptotic pore-forming protein gasdermin D inhibits inflammatory cell death and sepsis. Science Immunology. 3
Yang J, Liu Z, Wang C, et al. (2018) Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor. Proceedings of the National Academy of Sciences of the United States of America