Edward P. Cheng, Ph.D.

Affiliations: 
2012 Physiology and Biophysics University of Washington, Seattle, Seattle, WA 
Area:
Physiology Biology, General Biophysics
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Luis F. Santana grad student 2012 University of Washington
 (The role of coupled gating of L-type calcium channels in arrhythmogenesis in Timothy syndrome (LQT8).)
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Drum BM, Dixon RE, Yuan C, et al. (2014) Cellular mechanisms of ventricular arrhythmias in a mouse model of Timothy syndrome (long QT syndrome 8). Journal of Molecular and Cellular Cardiology. 66: 63-71
Dixon RE, Cheng EP, Mercado JL, et al. (2012) L-type Ca2+ channel function during Timothy syndrome. Trends in Cardiovascular Medicine. 22: 72-6
Dixon RE, Yuan C, Cheng EP, et al. (2012) Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels. Proceedings of the National Academy of Sciences of the United States of America. 109: 1749-54
Cheng EP, Yuan C, Navedo MF, et al. (2011) Restoration of normal L-type Ca2+ channel function during Timothy syndrome by ablation of an anchoring protein. Circulation Research. 109: 255-61
Santana LF, Cheng EP, Lederer WJ. (2010) How does the shape of the cardiac action potential control calcium signaling and contraction in the heart? Journal of Molecular and Cellular Cardiology. 49: 901-3
Navedo MF, Cheng EP, Yuan C, et al. (2010) Increased coupled gating of L-type Ca2+ channels during hypertension and Timothy syndrome. Circulation Research. 106: 748-56
Cheng EP, Yuan C, Navedo MF, et al. (2010) Activation of PKC-Alpha Increases Ca2+ Sparklet Activity in Cardiac Myocytes Biophysical Journal. 98: 15a-16a
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