Ryan C. Heller, Ph.D.

2006 Weill Cornell Medical College, New York, NY, United States 
Biochemistry, Molecular Biology
"Ryan Heller"
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Kenneth J. Marians grad student 2006 Weill Cornell Medical College
 (Mechanisms of replisome assembly and stalled fork reactivation at DNA replication blocks.)
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Heller RC, Kang S, Lam WM, et al. (2011) Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases. Cell. 146: 80-91
Randell JCW, Fan A, Chan C, et al. (2010) Mec1 Is One of Multiple Kinases that Prime the Mcm2-7 Helicase for Phosphorylation by Cdc7 Molecular Cell. 40: 353-363
Heller RC, Marians KJ. (2007) Non-replicative helicases at the replication fork. Dna Repair. 6: 945-52
Heller RC, Marians KJ. (2006) Replisome assembly and the direct restart of stalled replication forks. Nature Reviews. Molecular Cell Biology. 7: 932-43
Heller RC, Marians KJ. (2006) Replication fork reactivation downstream of a blocked nascent leading strand. Nature. 439: 557-62
Heller RC, Marians KJ. (2005) Unwinding of the nascent lagging strand by Rep and PriA enables the direct restart of stalled replication forks. The Journal of Biological Chemistry. 280: 34143-51
Heller RC, Marians KJ. (2005) The disposition of nascent strands at stalled replication forks dictates the pathway of replisome loading during restart. Molecular Cell. 17: 733-43
Sutton A, Heller RC, Landry J, et al. (2001) A novel form of transcriptional silencing by Sum1-1 requires Hst1 and the origin recognition complex Molecular and Cellular Biology. 21: 3514-3522
Landry J, Sutton A, Tafrov ST, et al. (2000) The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases Proceedings of the National Academy of Sciences of the United States of America. 97: 5807-5811
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