Jil C. Tardiff

Affiliations: 
Physiology and Biophysics Yeshiva University, New York, NY, United States 
Area:
Physiology Biology, General Biophysics
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"Jil Tardiff"
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Publications

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Lynn ML, Jimenez J, Castillo RL, et al. (2023) The HCM - Linked Mutation Arg92Leu in TNNT2 Allosterically Alters the cTnC - cTnI Interface and Disrupts the PKA-mediated Regulation of Myofilament Relaxation. Biorxiv : the Preprint Server For Biology
Lehman SJ, Meller A, Solieva SO, et al. (2023) Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies. Biorxiv : the Preprint Server For Biology
Chakraborti A, Tardiff JC, Schwartz SD. (2022) Insights into the Mechanism of the Cardiac Drug Omecamtiv Mecarbil─A Computational Study. The Journal of Physical Chemistry. B
Keyt LK, Duran JM, Bui QM, et al. (2022) Thin filament cardiomyopathies: A review of genetics, disease mechanisms, and emerging therapeutics. Frontiers in Cardiovascular Medicine. 9: 972301
Deranek AE, Baldo AP, Lynn ML, et al. (2022) Structure and Dynamics of the Flexible Cardiac Troponin T Linker Domain in a Fully Reconstituted Thin Filament. Biochemistry
Pioner JM, Vitale G, Gentile F, et al. (2022) Genotype-Driven Pathogenesis of Atrial Fibrillation in Hypertrophic Cardiomyopathy: The Case of Different Mutations. Frontiers in Physiology. 13: 864547
Mason AB, Lynn ML, Baldo AP, et al. (2021) Computational and biophysical determination of pathogenicity of variants of unknown significance in cardiac thin filament. Jci Insight
Chakraborti A, Baldo AP, Tardiff JC, et al. (2021) Investigation of the Recovery Stroke and ATP Hydrolysis and Changes Caused Due to the Cardiomyopathic Point Mutations in Human Cardiac β Myosin. The Journal of Physical Chemistry. B
Greenberg MJ, Tardiff JC. (2021) Complexity in genetic cardiomyopathies and new approaches for mechanism-based precision medicine. The Journal of General Physiology. 153
Powers JD, Kooiker KB, Mason AB, et al. (2020) Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts. Jci Insight
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