Jil C. Tardiff

Physiology and Biophysics Yeshiva University, New York, NY, United States 
Physiology Biology, General Biophysics
"Jil Tardiff"
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Abdullah S, Lynn ML, McConnell MT, et al. (2019) FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation. The Journal of Biological Chemistry
Szatkowski L, Lynn ML, Holeman T, et al. (2019) Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations. Acs Omega. 4: 6492-6501
Williams MR, Tardiff JC, Schwartz SD. (2018) The Mechanism of Cardiac Tropomyosin Transitions on Filamentous Actin as Revealed by all Atom Steered Molecular Dynamics Simulations. The Journal of Physical Chemistry Letters
McConnell M, Tal Grinspan L, Williams MR, et al. (2017) Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac Tropomyosin Overlap. Biochemistry
Jian Z, Chen YJ, Shimkunas R, et al. (2016) In Vivo Cannulation Methods for Cardiomyocytes Isolation from Heart Disease Models. Plos One. 11: e0160605
Behunin SM, Lopez-Pier MA, Mayfield RM, et al. (2016) Liver Kinase B 1 Complex Acts as a Novel Modifier of Myofilament Function and Localizes to the Z-Disk in Cardiac Myocytes. Archives of Biochemistry and Biophysics
Williams MR, Lehman SJ, Tardiff JC, et al. (2016) Atomic resolution probe for allostery in the regulatory thin filament. Proceedings of the National Academy of Sciences of the United States of America
Gollapudi SK, Tardiff JC, Chandra M. (2015) The functional effect of dilated cardiomyopathy mutation (R144W) in mouse cardiac troponin T is differently affected by α- and β-myosin heavy chain isoforms. American Journal of Physiology. Heart and Circulatory Physiology. 308: H884-93
Tardiff JC, Carrier L, Bers DM, et al. (2015) Targets for therapy in sarcomeric cardiomyopathies. Cardiovascular Research. 105: 457-70
van der Velden J, Ho CY, Tardiff JC, et al. (2015) Research priorities in sarcomeric cardiomyopathies. Cardiovascular Research. 105: 449-56
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