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Melissa E. Heard, Ph.D.

Affiliations: 
2014 Physiology and Biophysics University of Arkansas for Medical Sciences, United States 
Area:
Physiology Biology, Pathology
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"Melissa Heard"
Cross-listing: Cell Biology Tree

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Rosalia C. M. Simmen grad student 2014 UAMS
 (Analysis of Kruppel-like factors 9 and 13 in endometrial function and the pathogenesis of endometriosis.)

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Publications

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Heard ME, Melnyk SB, Simmen FA, et al. (2016) High-Fat Diet Promotion of Endometriosis in an Immunocompetent Mouse Model is Associated with Altered Peripheral and Ectopic Lesion Redox and Inflammatory Status. Endocrinology. en20161092
Heard ME, Besio R, Weis M, et al. (2016) Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation. Plos Genetics. 12: e1006002
Heard ME, Velarde MC, Giudice LC, et al. (2015) Krüppel-Like Factor 13 Deficiency in Uterine Endometrial Cells Contributes to Defective Steroid Hormone Receptor Signaling but Not Lesion Establishment in a Mouse Model of Endometriosis. Biology of Reproduction. 92: 140
Simmen RC, Heard ME, Simmen AM, et al. (2015) The Krüppel-like factors in female reproductive system pathologies. Journal of Molecular Endocrinology. 54: R89-R101
Heard ME, Simmons CD, Simmen FA, et al. (2014) Krüppel-like factor 9 deficiency in uterine endometrial cells promotes ectopic lesion establishment associated with activated notch and hedgehog signaling in a mouse model of endometriosis. Endocrinology. 155: 1532-46
Rahal OM, Machado HL, Montales MT, et al. (2013) Dietary suppression of the mammary CD29(hi)CD24(+) epithelial subpopulation and its cytokine/chemokine transcriptional signatures modifies mammary tumor risk in MMTV-Wnt1 transgenic mice. Stem Cell Research. 11: 1149-62
Heard ME, Pabona JM, Clayberger C, et al. (2012) The reproductive phenotype of mice null for transcription factor Krüppel-like factor 13 suggests compensatory function of family member Krüppel-like factor 9 in the peri-implantation uterus. Biology of Reproduction. 87: 115
Simmons CD, Pabona JM, Heard ME, et al. (2011) Krüppel-like factor 9 loss-of-expression in human endometrial carcinoma links altered expression of growth-regulatory genes with aberrant proliferative response to estrogen. Biology of Reproduction. 85: 378-85
Heard M, Pabona JM, Clayberger C, et al. (2011) The Reproductive Phenotype of Mice Null for Transcription Factor Krüppel-Like Factor 13 (KLF13) Reveals Functions Distinct from Its Family Member KLF9 in Normal Female Fertility. Biology of Reproduction. 85: 464-464
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