Aaron Schimmer

Affiliations: 
Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
Cell Biology, Molecular Biology, Oncology
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"Aaron Schimmer"
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Publications

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Su Y, Carter JL, Li X, et al. (2024) The imipridone ONC213 targets α-ketoglutarate dehydrogenase to induce mitochondrial stress and suppress oxidative phosphorylation in acute myeloid leukemia. Cancer Research
Akiyama H, Zhao R, Ostermann LB, et al. (2023) Mitochondrial regulation of GPX4 inhibition-mediated ferroptosis in acute myeloid leukemia. Leukemia
Fazzari F, Chow S, Cheung M, et al. (2022) Combined Targeting of the Glutathione and Thioredoxin Antioxidant Systems in Pancreatic Cancer. Acs Pharmacology & Translational Science. 5: 1070-1078
Lee JB, Khan DH, Hurren R, et al. (2021) Venetoclax enhances T cell-mediated antileukemic activity by increasing ROS production. Blood. 138: 234-245
Feng Y, Nouri K, Schimmer AD. (2021) Mitochondrial ATP-Dependent Proteases-Biological Function and Potential Anti-Cancer Targets. Cancers. 13
Lee J, Khan DH, Hurren R, et al. (2021) Venetoclax enhances T cell-mediated anti-leukemic activity by increasing ROS production. Blood
Tcheng M, Roma A, Ahmed N, et al. (2021) Very long chain fatty acid metabolism is required in acute myeloid leukemia. Blood
Barghout SH, Aman A, Nouri K, et al. (2021) A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity. Jci Insight
Schimmer AD, Singh RP, Seneviratne AK, et al. (2020) Transduction of Primary AML Cells with Lentiviral Vector for Study or Engraftment. Star Protocols. 1: 100163
Nouri K, Feng Y, Schimmer AD. (2020) Mitochondrial ClpP serine protease-biological function and emerging target for cancer therapy. Cell Death & Disease. 11: 841
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