David Spaner

Affiliations: 
Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
Medical Biophysics, Cell Biology, Biochemistry, Oncology, Immunology
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"David Spaner"
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Publications

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Spaner DE, McCaw L, Wang G, et al. (2019) Persistent janus kinase-signaling in chronic lymphocytic leukemia patients on ibrutinib: Results of a phase I trial. Cancer Medicine
Liu T, Xia L, Yao Y, et al. (2019) Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis. Cell Death & Disease. 10: 117
Shi Y, Wang G, Muhowski EM, et al. (2019) Ibrutinib reprograms the glucocorticoid receptor in chronic lymphocytic leukemia cells. Leukemia
Song J, Yuan C, Yang J, et al. (2018) Novel flavagline-like compounds with potent Fli-1 inhibitory activity suppress diverse types of leukemia. The Febs Journal
Spaner DE, Venema R, Huang J, et al. (2018) Association of blood IgG with tumor necrosis factor-alpha and clinical course of chronic lymphocytic leukemia. Ebiomedicine
Zhu F, McCaw L, Spaner DE, et al. (2018) Targeting the IL-17/IL-6 axis can alter growth of Chronic Lymphocytic Leukemia in vivo/in vitro. Leukemia Research. 66: 28-38
McCaw L, Shi Y, Wang G, et al. (2016) Low Density Lipoproteins Amplify Cytokine-signaling in Chronic Lymphocytic Leukemia Cells. Ebiomedicine
Oppermann S, Lam AJ, Tung S, et al. (2016) Janus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells. Oncotarget
Oppermann S, Ylanko J, Shi Y, et al. (2016) Identification of kinase inhibitors that overcome venetoclax resistance in activated CLL cells by high-content screening. Blood
Duran CL, Lee DW, Jung JU, et al. (2016) NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-κB pathway. Oncogenesis. 5: e231
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