Thomas L. Ciardelli

Affiliations: 
Dartmouth College, Hanover, NH, United States 
Area:
Biochemistry, Pharmacology, General Biophysics
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Rao BM, Girvin AT, Ciardelli T, et al. (2003) Interleukin-2 mutants with enhanced alpha-receptor subunit binding affinity. Protein Engineering. 16: 1081-7
Liparoto SF, Myszka DG, Wu Z, et al. (2002) Analysis of the role of the interleukin-2 receptor gamma chain in ligand binding. Biochemistry. 41: 2543-51
Fallon EM, Liparoto SF, Lee KJ, et al. (2000) Increased endosomal sorting of ligand to recycling enhances potency of an interleukin-2 analog. The Journal of Biological Chemistry. 275: 6790-7
Liparoto SF, Ciardelli TL. (1999) Biosensor analysis of the interleukin-2 receptor complex. Journal of Molecular Recognition : Jmr. 12: 316-21
Wu Z, Goldstein B, Laue TM, et al. (1999) Solution assembly of the pseudo-high affinity and intermediate affinity interleukin-2 receptor complexes. Protein Science : a Publication of the Protein Society. 8: 482-9
Nielsen OH, Kirman I, Johnson K, et al. (1998) The circulating common gamma chain (CD132) in inflammatory bowel disease. The American Journal of Gastroenterology. 93: 323-8
Wang R, Ciardelli TL, Russell JH. (1997) Partial signaling by cytokines: cytokine regulation of cell cycle and Fas-dependent, activation-induced death in CD4+ subsets. Cellular Immunology. 182: 152-60
Lee BL, Ciardelli TL. (1997) Structural modifications of interleukin-2 at positions 47 and 65. Biochemical and Biophysical Research Communications. 233: 309-15
Buchli PJ, Wu Z, Ciardelli TL. (1997) The functional display of interleukin-2 on filamentous phage. Archives of Biochemistry and Biophysics. 339: 79-84
Myszka DG, Arulanantham PR, Sana T, et al. (1996) Kinetic analysis of ligand binding to interleukin-2 receptor complexes created on an optical biosensor surface. Protein Science : a Publication of the Protein Society. 5: 2468-78
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