William J Lehman
Affiliations: | Boston University, Boston, MA, United States |
Area:
General BiophysicsWebsite:
https://www.bumc.bu.edu/busm/profile/william-lehman/Google:
"William Jeffrey Lehman" OR "William J Lehman"Mean distance: (not calculated yet)
Parents
Sign in to add mentorLionel Israel Rebhun | grad student | 1966-1969 | Princeton (Neurotree) | |
(The structural elements responsible for contraction in the ciliate Spirostomum) | ||||
Andrew G. Szent-Györgyi | post-doc | 1969-1972 | Brandeis (Cell Biology Tree) | |
Richard T. Tregear | research scientist | 1973-1973 | Oxford (Physiology Academic Tree) | |
Kenneth C. Holmes | research scientist | 1975-1975 | MPI for Medical Research (Computational Biology Tree) |
Children
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Publications
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Lehman W, Rynkiewicz MJ. (2023) Troponin-I-induced tropomyosin pivoting defines thin-filament function in relaxed and active muscle. The Journal of General Physiology. 155 |
Halder SS, Rynkiewicz MJ, Creso JG, et al. (2023) Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TPM1 variant S215L. Pnas Nexus. 2: pgad011 |
Doran MH, Rynkiewicz MJ, Rassici D, et al. (2023) Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. The Journal of General Physiology. 155 |
Doran MH, Rynkiewicz MJ, Pavadai E, et al. (2022) Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. The Journal of General Physiology. 155 |
Rynkiewicz MJ, Pavadai E, Lehman W. (2022) Modeling Human Cardiac Thin Filament Structures. Frontiers in Physiology. 13: 932333 |
Suphamungmee W, Lehman W, Morgan KG. (2022) Functional Remodeling of the Contractile Smooth Muscle Cell Cortex, a Provocative Concept, Supported by Direct Visualization of Cortical Remodeling. Biology. 11 |
Pavadai E, Rynkiewicz MJ, Yang Z, et al. (2022) Modulation of cardiac thin filament structure by phosphorylated troponin-I analyzed by protein-protein docking and molecular dynamics simulation. Archives of Biochemistry and Biophysics. 725: 109282 |
Teekakirikul P, Zhu W, Xu X, et al. (2022) Genetic resiliency associated with dominant lethal mutation causing atrial septal defect with high heritability. Cell Reports. Medicine. 3: 100501 |
Doran MH, Lehman W. (2021) The Central Role of the F-Actin Surface in Myosin Force Generation. Biology. 10 |
Sewanan LR, Park J, Rynkiewicz MJ, et al. (2021) Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation. The Journal of General Physiology. 153 |