Barbara A. Seaton

Affiliations: 
Physiology and Biophysics Boston University, Boston, MA, United States 
Area:
Medical Biophysics
Website:
http://www.bumc.bu.edu/phys-biophys/people/faculty/seaton/
Google:
"Barbara Ann Seaton"
Mean distance: (not calculated yet)
 

Parents

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Gregory A. Petsko grad student 1983 MIT (Chemistry Tree)
 (Biophysical studies of protein conformation.)
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Publications

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van Eijk M, Rynkiewicz MJ, Khatri K, et al. (2018) Lectin-mediated binding and sialoglycans of porcine surfactant protein D synergistically neutralize influenza A virus. The Journal of Biological Chemistry
Rynkiewicz MJ, Wu H, Cafarella TR, et al. (2017) Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop. Biochemistry
Goh BC, Wu H, Rynkiewicz MJ, et al. (2016) Elucidation of Lipid Binding Sites on Lung Surfactant Protein A Using X-ray Crystallography, Mutagenesis, and Molecular Dynamics Simulations. Biochemistry
Goh BC, Rynkiewicz MJ, McCormack FX, et al. (2015) Unraveling the Dual Role of Surfactant Protein a at Atomistic Detail Biophysical Journal. 108: 255a-256a
Goh BC, Zou X, Rynkiewicz MJ, et al. (2013) Effect of Two Point Mutations in Lung Surfactant Protein-D on Enhancing its Inhibition Activity Against Influenza a Virus Biophysical Journal. 104: 556a
van Eijk M, Rynkiewicz MJ, White MR, et al. (2012) A unique sugar-binding site mediates the distinct anti-influenza activity of pig surfactant protein D. The Journal of Biological Chemistry. 287: 26666-77
Yu P, Strug I, Cafarella TR, et al. (2012) Site-specific crosslinking of annexin proteins by 1,4-benzoquinone: a novel crosslinker for the formation of protein dimers and diverse protein conjugates. Organic & Biomolecular Chemistry. 10: 4500-4
Chong Goh B, Zou X, Rynkiewicz MJ, et al. (2012) Mechanism of Interaction Between Lung Surfactant Protein-D and Influenza A Virus Hemagglutinin Biophysical Journal. 102: 63a
Crouch E, Nikolaidis N, McCormack FX, et al. (2011) Mutagenesis of surfactant protein D informed by evolution and x-ray crystallography enhances defenses against influenza A virus in vivo. The Journal of Biological Chemistry. 286: 40681-92
van Eijk M, Bruinsma L, Hartshorn KL, et al. (2011) Introduction of N-linked glycans in the lectin domain of surfactant protein D: impact on interactions with influenza A viruses. The Journal of Biological Chemistry. 286: 20137-51
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