David M. Virshup

Affiliations: 
University of Utah, Salt Lake City, UT 
Area:
Biochemistry, Molecular Physics, Molecular Biology
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"David Virshup"
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Publications

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Philpott JM, Freeberg AM, Park J, et al. (2023) PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period. Molecular Cell. 83: 1677-1692.e8
Francisco JC, Virshup DM. (2022) Casein Kinase 1 and Human Disease: Insights From the Circadian Phosphoswitch. Frontiers in Molecular Biosciences. 9: 911764
Narasimamurthy R, Virshup DM. (2021) The phosphorylation switch that regulates ticking of the circadian clock. Molecular Cell
Masuda S, Narasimamurthy R, Yoshitane H, et al. (2020) Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch. Proceedings of the National Academy of Sciences of the United States of America
Philpott JM, Narasimamurthy R, Ricci CG, et al. (2020) Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch. Elife. 9
Philpott JM, Narasimamurthy R, Ricci CG, et al. (2020) Author response: Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch Elife
Ricci CG, Philpott JM, Narasimamurthy R, et al. (2020) Free Energy Landscape of Casein Kinase Delta and its Implications for Circadian Rhythm Biophysical Journal. 118: 207a-208a
Zhong Z, Virshup DM. (2019) Wnt signaling and drug resistance in cancer. Molecular Pharmacology
Idris M, Harmston N, Petretto EG, et al. (2019) Broad regulation of gene isoform expression by Wnt signaling in cancer. Rna (New York, N.Y.)
Zhong Z, Sepramaniam S, Chew XH, et al. (2019) PORCN inhibition synergizes with PI3K/mTOR inhibition in Wnt-addicted cancers. Oncogene
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