Annie A. Lumen, Ph.D.

Affiliations: 
2011 Drexel University, Philadelphia, PA, United States 
Area:
Molecular Biology, Biochemistry, Pharmacology
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Joe Bentz grad student 2011 Drexel
 (Mechanistic Understanding of P-gp Mediated Transport and Inhibition Kinetics across a Confluent monolayer of MDCKII-hMDR1 cells using a Mass Action Kinetic Model.)
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Publications

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Lumen AA, Li L, Li J, et al. (2013) Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp. Plos One. 8: e69394
Lumen AA, Acharya P, Polli JW, et al. (2010) If the KI is defined by the free energy of binding to P-glycoprotein, which kinetic parameters define the IC50 for the Madin-Darby canine kidney II cell line overexpressing human multidrug resistance 1 confluent cell monolayer? Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 260-9
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