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Kelly M. Knee, Ph.D.

Affiliations: 
2007 Wesleyan University, Middletown, CT, United States 
Area:
General Biophysics
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Parents

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Ishita Mukerji grad student 2007 Wesleyan
 (Kinetic and structural studies of Hb S fiber formation monitored by UV resonance Raman spectroscopy.)
Jonathan A. King post-doc 2007-2011 MIT (Chemistry Tree)

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Publications

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Sergeeva OA, Yang J, King JA, et al. (2014) Group II archaeal chaperonin recognition of partially folded human γD-crystallin mutants. Protein Science : a Publication of the Protein Society. 23: 693-702
Knee KM, Sergeeva OA, King JA. (2013) Human TRiC complex purified from HeLa cells contains all eight CCT subunits and is active in vitro. Cell Stress & Chaperones. 18: 137-44
Pereira JH, Ralston CY, Douglas NR, et al. (2012) Mechanism of nucleotide sensing in group II chaperonins. The Embo Journal. 31: 731-40
Goulet DR, Knee KM, King JA. (2011) Inhibition of unfolding and aggregation of lens protein human gamma D crystallin by sodium citrate. Experimental Eye Research. 93: 371-81
Knee KM, Goulet DR, Zhang J, et al. (2011) The group II chaperonin Mm-Cpn binds and refolds human γD crystallin. Protein Science : a Publication of the Protein Society. 20: 30-41
Pereira JH, Ralston CY, Douglas NR, et al. (2010) Crystal structures of a group II chaperonin reveal the open and closed states associated with the protein folding cycle. The Journal of Biological Chemistry. 285: 27958-66
Knee KM, Mukerji I. (2009) Real time monitoring of sickle cell hemoglobin fiber formation by UV resonance Raman spectroscopy. Biochemistry. 48: 9903-11
Knee KM, Dixit SB, Aitken CE, et al. (2008) Spectroscopic and molecular dynamics evidence for a sequential mechanism for the A-to-B transition in DNA. Biophysical Journal. 95: 257-72
Knee KM, Roden CK, Flory MR, et al. (2007) The role of beta93 Cys in the inhibition of Hb S fiber formation. Biophysical Chemistry. 127: 181-93
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